Martin L Duennwald, PhD - Publications

protein folding, Huntington's disease, aging

20 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Chung CZ, Jaramillo JE, Ellis MJ, Bour DYN, Seidl LE, Jo DHS, Turk MA, Mann MR, Bi Y, Haniford DB, Duennwald ML, Heinemann IU. RNA surveillance by uridylation-dependent RNA decay in Schizosaccharomyces pombe. Nucleic Acids Research. PMID 30715470 DOI: 10.1093/nar/gkz043  0.32
2013 Duennwald ML. Yeast as a platform to explore polyglutamine toxicity and aggregation. Methods in Molecular Biology (Clifton, N.J.). 1017: 153-61. PMID 23719914 DOI: 10.1007/978-1-62703-438-8_11  1
2012 Duennwald ML, Echeverria A, Shorter J. Small heat shock proteins potentiate amyloid dissolution by protein disaggregases from yeast and humans. Plos Biology. 10: e1001346. PMID 22723742 DOI: 10.1371/journal.pbio.1001346  1
2012 Chafekar SM, Wisén S, Thompson AD, Echeverria A, Walter GM, Evans CG, Makley LN, Gestwicki JE, Duennwald ML. Pharmacological tuning of heat shock protein 70 modulates polyglutamine toxicity and aggregation. Acs Chemical Biology. 7: 1556-64. PMID 22709427 DOI: 10.1021/cb300166p  1
2012 Chafekar SM, Duennwald ML. Impaired heat shock response in cells expressing full-length polyglutamine-expanded huntingtin. Plos One. 7: e37929. PMID 22649566 DOI: 10.1371/journal.pone.0037929  1
2012 Duennwald ML. Growth assays to assess polyglutamine toxicity in yeast. Journal of Visualized Experiments : Jove. e3461. PMID 22415521 DOI: 10.3791/3461  1
2012 Riva L, Koeva M, Yildirim F, Pirhaji L, Dinesh D, Mazor T, Duennwald ML, Fraenkel E. Polyglutamine expanded huntingtin dramatically alters the genome-wide binding of HSF1 Journal of Huntington's Disease. 1: 33-45. DOI: 10.3233/JHD-2012-120020  1
2011 Duennwald ML. Polyglutamine misfolding in yeast: toxic and protective aggregation. Prion. 5: 285-90. PMID 22052348 DOI: 10.4161/pri.18071  1
2011 Walter GM, Smith MC, Wisén S, Basrur V, Elenitoba-Johnson KS, Duennwald ML, Kumar A, Gestwicki JE. Ordered assembly of heat shock proteins, Hsp26, Hsp70, Hsp90, and Hsp104, on expanded polyglutamine fragments revealed by chemical probes. The Journal of Biological Chemistry. 286: 40486-93. PMID 21969373 DOI: 10.1074/jbc.M111.284448  1
2011 Duennwald ML. Monitoring polyglutamine toxicity in yeast. Methods (San Diego, Calif.). 53: 232-7. PMID 21144902 DOI: 10.1016/j.ymeth.2010.12.001  1
2010 Duennwald ML, Shorter J. Countering amyloid polymorphism and drug resistance with minimal drug cocktails. Prion. 4: 244-51. PMID 20935457 DOI: 10.4161/pri.4.4.13597  1
2009 Roberts BE, Duennwald ML, Wang H, Chung C, Lopreiato NP, Sweeny EA, Knight MN, Shorter J. A synergistic small-molecule combination directly eradicates diverse prion strain structures. Nature Chemical Biology. 5: 936-46. PMID 19915541 DOI: 10.1038/nchembio.246  1
2008 Duennwald ML, Lindquist S. Impaired ERAD and ER stress are early and specific events in polyglutamine toxicity. Genes & Development. 22: 3308-19. PMID 19015277 DOI: 10.1101/gad.1673408  1
2008 Wang H, Duennwald ML, Roberts BE, Rozeboom LM, Zhang YL, Steele AD, Krishnan R, Su LJ, Griffin D, Mukhopadhyay S, Hennessy EJ, Weigele P, Blanchard BJ, King J, Deniz AA, et al. Direct and selective elimination of specific prions and amyloids by 4,5-dianilinophthalimide and analogs. Proceedings of the National Academy of Sciences of the United States of America. 105: 7159-64. PMID 18480256 DOI: 10.1073/pnas.0801934105  1
2008 Douglas PM, Treusch S, Ren HY, Halfmann R, Duennwald ML, Lindquist S, Cyr DM. Chaperone-dependent amyloid assembly protects cells from prion toxicity. Proceedings of the National Academy of Sciences of the United States of America. 105: 7206-11. PMID 18480252 DOI: 10.1073/pnas.0802593105  1
2006 Ehrnhoefer DE, Duennwald M, Markovic P, Wacker JL, Engemann S, Roark M, Legleiter J, Marsh JL, Thompson LM, Lindquist S, Muchowski PJ, Wanker EE. Green tea (-)-epigallocatechin-gallate modulates early events in huntingtin misfolding and reduces toxicity in Huntington's disease models. Human Molecular Genetics. 15: 2743-51. PMID 16893904 DOI: 10.1093/hmg/ddl210  1
2006 Duennwald ML, Jagadish S, Muchowski PJ, Lindquist S. Flanking sequences profoundly alter polyglutamine toxicity in yeast. Proceedings of the National Academy of Sciences of the United States of America. 103: 11045-50. PMID 16832050 DOI: 10.1073/pnas.0604547103  1
2006 Duennwald ML, Jagadish S, Giorgini F, Muchowski PJ, Lindquist S. A network of protein interactions determines polyglutamine toxicity. Proceedings of the National Academy of Sciences of the United States of America. 103: 11051-6. PMID 16832049 DOI: 10.1073/pnas.0604548103  1
2005 Cashikar AG, Duennwald M, Lindquist SL. A chaperone pathway in protein disaggregation. Hsp26 alters the nature of protein aggregates to facilitate reactivation by Hsp104. The Journal of Biological Chemistry. 280: 23869-75. PMID 15845535 DOI: 10.1074/jbc.M502854200  1
2004 Colby DW, Chu Y, Cassady JP, Duennwald M, Zazulak H, Webster JM, Messer A, Lindquist S, Ingram VM, Wittrup KD. Potent inhibition of huntingtin aggregation and cytotoxicity by a disulfide bond-free single-domain intracellular antibody. Proceedings of the National Academy of Sciences of the United States of America. 101: 17616-21. PMID 15598740 DOI: 10.1073/pnas.0408134101  1
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