Zuhier Awan, Ph.D. - Publications

Affiliations: 
2014 Medicine Université de Montréal, Montréal, Canada 
Area:
Genetics

37 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Alzahrani SH, Bima A, Algethami MR, Awan Z. Assessment of medical intern's knowledge, awareness and practice of familial hypercholesterolemia at academic institutes in Jeddah, Saudi Arabia. Lipids in Health and Disease. 19: 101. PMID 32438925 DOI: 10.1186/S12944-020-01266-Y  0.386
2019 Momtazi-Borojeni AA, Sabouri-Rad S, Gotto AM, Pirro M, Banach M, Awan Z, Barreto GE, Sahebkar A. PCSK9 and inflammation: a review of experimental and clinical evidence. European Heart Journal. Cardiovascular Pharmacotherapy. PMID 31236571 DOI: 10.1093/Ehjcvp/Pvz022  0.39
2018 Ruel I, Brisson D, Aljenedil S, Awan Z, Baass A, Bélanger A, Bergeron J, Bewick D, Brophy JM, Brunham LR, Couture P, Dufour R, Francis GA, Frohlich J, Gagné C, et al. Simplified Canadian Definition for Familial Hypercholesterolemia. The Canadian Journal of Cardiology. PMID 30093300 DOI: 10.1016/J.Cjca.2018.05.015  0.4
2018 Gauthier MS, Awan Z, Bouchard A, Champagne J, Tessier S, Faubert D, Chabot K, Garneau PY, Rabasa-Lhoret R, Seidah NG, Ridker PM, Genest J, Coulombe B. Posttranslational modification of proprotein convertase subtilisin/kexin type 9 is differentially regulated in response to distinct cardiometabolic treatments as revealed by targeted proteomics. Journal of Clinical Lipidology. PMID 29699916 DOI: 10.1016/J.Jacl.2018.03.092  0.522
2017 Rashidi OM, H Nazar FA, Alama MN, Awan ZA. Interpreting the Mechanism of APOE (p.Leu167del) Mutation in the Incidence of Familial Hypercholesterolemia; An In-silico Approach. The Open Cardiovascular Medicine Journal. 11: 84-93. PMID 29204218 DOI: 10.2174/1874192401711010084  0.315
2017 Morad FA, Rashidi OM, Sadath SS, Al-Allaf FA, Athar M, Alama MN, Edris SE, Bondagji NS, Shaik NA, Banaganapalli B, Awan Z. In Silico Approach to Investigate the Structural and Functional Attributes of Familial Hypercholesterolemia Variants Reported in the Saudi Population. Journal of Computational Biology : a Journal of Computational Molecular Cell Biology. PMID 29172679 DOI: 10.1089/Cmb.2017.0018  0.345
2017 Alallaf F, H Nazar FA, Alnefaie M, Almaymuni A, Rashidi OM, Alhabib K, Alnouri F, Alama MN, Athar M, Awan Z. The Spectrum of Familial Hypercholesterolemia (FH) in Saudi Arabia: Prime Time for Patient FH Registry. The Open Cardiovascular Medicine Journal. 11: 66-75. PMID 28868092 DOI: 10.2174/1874192401711010066  0.412
2017 Essalmani R, Susan-Resiga D, Guillemot J, Kim W, Sachan V, Awan Z, Chamberland A, Asselin MC, Ly K, Desjardins R, Day R, Prat A, Seidah NG. Thrombin activation of protein C requires prior processing by a liver proprotein convertase. The Journal of Biological Chemistry. 292: 13565. PMID 28821605 DOI: 10.1074/jbc.A116.77040  0.33
2017 Essalmani R, Susan-Resiga D, Guillemot J, WooJin K, Sachan V, Awan Z, Chamberland A, Asselin MC, Ly K, Desjardins R, Day R, Prat A, Seidah NG. Thrombin Activation of Protein C Requires Prior Processing by a Liver Proprotein Convertase. The Journal of Biological Chemistry. PMID 28468828 DOI: 10.1074/Jbc.M116.770040  0.431
2017 Al Kindi M, Bélanger AM, Sayegh K, Senouci S, Aljenedil S, Sivakumaran L, Ruel I, Al Rasadi K, Al Waili K, Awan Z, Valenti D, Genest J. Aortic Calcification Progression in Heterozygote Familial Hypercholesterolemia. The Canadian Journal of Cardiology. 33: 658-665. PMID 28449836 DOI: 10.1016/J.Cjca.2017.02.001  0.312
2016 Susan-Resiga D, Girard E, Kiss RS, Essalmani R, Hamelin J, Asselin MC, Awan Z, Butkinaree C, Fleury A, Soldera A, Dory YL, Baass A, Seidah NG. A novel mechanism causing familial hypercholesterolemia: The proprotein convertase subtilisin/kexin type 9-resistant Arg410Ser LDL receptor mutation. The Journal of Biological Chemistry. PMID 27998977 DOI: 10.1074/Jbc.M116.769430  0.543
2016 Al Sayed N, Al Waili K, Alawadi F, Al-Ghamdi S, Al Mahmeed W, Al-Nouri F, Al Rukhaimi M, Al-Rasadi K, Awan Z, Farghaly M, Hassanein M, Sabbour H, Zubaid M, Barter P. Consensus clinical recommendations for the management of plasma lipid disorders in the Middle East. International Journal of Cardiology. 225: 268-283. PMID 27741487 DOI: 10.1016/J.Ijcard.2016.09.081  0.321
2016 Al Rasadi K, Almahmeed W, AlHabib KF, Abifadel M, Farhan HA, AlSifri S, Jambart S, Zubaid M, Awan Z, Al-Waili K, Barter P. Dyslipidaemia in the Middle East: Current status and a call for action. Atherosclerosis. PMID 27522462 DOI: 10.1016/J.Atherosclerosis.2016.07.925  0.339
2016 Awan Z, Denis M, Roubtsova A, Essalmani R, Marcinkiewicz J, Awan A, Gram H, Seidah NG, Genest J. Reducing Vascular Calcification by Anti-IL-1β Monoclonal Antibody in a Mouse Model of Familial Hypercholesterolemia. Angiology. 67: 157-67. PMID 25904765 DOI: 10.1177/0003319715583205  0.492
2015 Bhat M, Skill N, Marcus V, Deschenes M, Tan X, Bouteaud J, Negi S, Awan Z, Aikin R, Kwan J, Amre R, Tabaries S, Hassanain M, Seidah NG, Maluccio M, et al. Decreased PCSK9 expression in human hepatocellular carcinoma. Bmc Gastroenterology. 15: 176. PMID 26674961 DOI: 10.1186/S12876-015-0371-6  0.443
2015 Bamimore MA, Zaid A, Banerjee Y, Al-Sarraf A, Abifadel M, Seidah NG, Al-Waili K, Al-Rasadi K, Awan Z. Familial hypercholesterolemia mutations in the Middle Eastern and North African region: a need for a national registry. Journal of Clinical Lipidology. 9: 187-94. PMID 25911074 DOI: 10.1016/J.Jacl.2014.11.008  0.465
2015 Gauthier MS, Pérusse JR, Awan Z, Bouchard A, Tessier S, Champagne J, Krastins B, Byram G, Chabot K, Garneau P, Rabasa-Lhoret R, Faubert D, Lopez MF, Seidah NG, Coulombe B. A semi-automated mass spectrometric immunoassay coupled to selected reaction monitoring (MSIA-SRM) reveals novel relationships between circulating PCSK9 and metabolic phenotypes in patient cohorts. Methods (San Diego, Calif.). 81: 66-73. PMID 25770357 DOI: 10.1016/J.Ymeth.2015.03.003  0.485
2014 Awan Z, Aljenedil S, Rosenblatt DS, Cusson J, Gilfix BM, Genest J. Severe hyperhomocysteinemia due to cystathionine β-synthase deficiency, and Factor V Leiden mutation in a patient with recurrent venous thrombosis. Thrombosis Journal. 12: 30. PMID 25516723 DOI: 10.1186/S12959-014-0030-0  0.301
2014 Awan Z, Baass A, Genest J. Proprotein convertase subtilisin/kexin type 9 (PCSK9): lessons learned from patients with hypercholesterolemia. Clinical Chemistry. 60: 1380-9. PMID 25248569 DOI: 10.1373/Clinchem.2014.225946  0.306
2014 Iatan I, Choi HY, Ruel I, Reddy MV, Kil H, Lee J, Odeh MA, Salah Z, Abu-Remaileh M, Weissglas-Volkov D, Nikkola E, Civelek M, Awan Z, Croce CM, Aqeilan RI, et al. The WWOX gene modulates high-density lipoprotein and lipid metabolism. Circulation. Cardiovascular Genetics. 7: 491-504. PMID 24871327 DOI: 10.1161/Circgenetics.113.000248  0.419
2014 Awan Z, Dubuc G, Faraj M, Dufour R, Seidah NG, Davignon J, Rabasa-Lhoret R, Baass A. The effect of insulin on circulating PCSK9 in postmenopausal obese women. Clinical Biochemistry. 47: 1033-9. PMID 24721682 DOI: 10.1016/J.Clinbiochem.2014.03.022  0.499
2014 Seidah NG, Awan Z, Chrétien M, Mbikay M. PCSK9: a key modulator of cardiovascular health. Circulation Research. 114: 1022-36. PMID 24625727 DOI: 10.1161/Circresaha.114.301621  0.549
2014 Awan Z, Dubuc G, Faraj M, Dufour R, Seidah N, Davignon J, Rabasa-Lhoret R, Baass A. Insulin Infusion Acutely Downregulates Circulating PCSK9 in Human* Journal of Clinical Lipidology. 8: 302. DOI: 10.1016/J.Jacl.2014.02.022  0.389
2013 Awan Z, Choi HY, Stitziel N, Ruel I, Bamimore MA, Husa R, Gagnon MH, Wang RH, Peloso GM, Hegele RA, Seidah NG, Kathiresan S, Genest J. APOE p.Leu167del mutation in familial hypercholesterolemia. Atherosclerosis. 231: 218-22. PMID 24267230 DOI: 10.1016/J.Cjca.2013.07.652  0.5
2013 Awan Z, Delvin EE, Levy E, Genest J, Davignon J, Seidah NG, Baass A. Regional distribution and metabolic effect of PCSK9 insLEU and R46L gene mutations and apoE genotype. The Canadian Journal of Cardiology. 29: 927-33. PMID 23743349 DOI: 10.1016/J.Cjca.2013.03.004  0.491
2013 Fantus D, Awan Z, Seidah NG, Genest J. Aortic calcification: Novel insights from familial hypercholesterolemia and potential role for the low-density lipoprotein receptor. Atherosclerosis. 226: 9-15. PMID 23040868 DOI: 10.1016/J.Atherosclerosis.2012.08.026  0.532
2012 Awan Z, Seidah NG, MacFadyen JG, Benjannet S, Chasman DI, Ridker PM, Genest J. Rosuvastatin, proprotein convertase subtilisin/kexin type 9 concentrations, and LDL cholesterol response: the JUPITER trial. Clinical Chemistry. 58: 183-9. PMID 22065156 DOI: 10.1373/Clinchem.2011.172932  0.523
2012 Alwaili K, Bailey D, Awan Z, Bailey SD, Ruel I, Hafiane A, Krimbou L, Laboissiere S, Genest J. The HDL proteome in acute coronary syndromes shifts to an inflammatory profile. Biochimica Et Biophysica Acta. 1821: 405-15. PMID 21840418 DOI: 10.1016/J.Bbalip.2011.07.013  0.386
2011 Awan Z, Denis M, Bailey D, Giaid A, Prat A, Goltzman D, Seidah NG, Genest J. The LDLR deficient mouse as a model for aortic calcification and quantification by micro-computed tomography. Atherosclerosis. 219: 455-62. PMID 22051553 DOI: 10.1016/J.Atherosclerosis.2011.08.035  0.533
2011 Roubtsova A, Munkonda MN, Awan Z, Marcinkiewicz J, Chamberland A, Lazure C, Cianflone K, Seidah NG, Prat A. Circulating proprotein convertase subtilisin/kexin 9 (PCSK9) regulates VLDLR protein and triglyceride accumulation in visceral adipose tissue. Arteriosclerosis, Thrombosis, and Vascular Biology. 31: 785-91. PMID 21273557 DOI: 10.1161/Atvbaha.110.220988  0.504
2010 Awan Z, Alwaili K, Alshahrani A, Langsetmo L, Goltzman D, Genest J. Calcium homeostasis and skeletal integrity in individuals with familial hypercholesterolemia and aortic calcification. Clinical Chemistry. 56: 1599-607. PMID 20702785 DOI: 10.1373/Clinchem.2010.147066  0.381
2010 Alwaili K, Awan Z, Alshahrani A, Genest J. High-density lipoproteins and cardiovascular disease: 2010 update. Expert Review of Cardiovascular Therapy. 8: 413-23. PMID 20222819 DOI: 10.1586/Erc.10.4  0.434
2009 Alrasadi K, Alwaili K, Awan Z, Valenti D, Couture P, Genest J. Aortic calcifications in familial hypercholesterolemia: potential role of the low-density lipoprotein receptor gene. American Heart Journal. 157: 170-6. PMID 19081415 DOI: 10.1016/J.Ahj.2008.08.021  0.407
2008 Alrasadi K, Awan Z, Alwaili K, Ruel I, Hafiane A, Krimbou L, Genest J. Comparison of treatment of severe high-density lipoprotein cholesterol deficiency in men with daily atorvastatin (20 mg) versus fenofibrate (200 mg) versus extended-release niacin (2 g). The American Journal of Cardiology. 102: 1341-7. PMID 18993152 DOI: 10.1016/J.Amjcard.2008.07.010  0.418
2008 Awan Z, Alrasadi K, Francis GA, Hegele RA, McPherson R, Frohlich J, Valenti D, de Varennes B, Marcil M, Gagne C, Genest J, Couture P. Vascular calcifications in homozygote familial hypercholesterolemia. Arteriosclerosis, Thrombosis, and Vascular Biology. 28: 777-85. PMID 18239150 DOI: 10.1161/Atvbaha.107.160408  0.375
2008 Awan Z, Waili KA, Alrasadi K, Genest J. Treatment of low high-density lipoprotein cholesterol Canadian Journal of Cardiology. 24. DOI: 10.1016/S0828-282X(08)71035-3  0.416
1995 Awan ZA, Baseer A. A study on serum triglyceride and lipoproteins cholesterol in coronary heart disease patients Jpma. the Journal of the Pakistan Medical Association. 45: 263-266. PMID 8714621  0.32
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