Mohamed Abu-Farha, Ph.D. - Publications

Affiliations: 
2011 University of Ottawa, Ottawa, ON, Canada 
Area:
Biochemistry

46 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Hebbar P, Abubaker JA, Abu-Farha M, Alsmadi O, Elkum N, Alkayal F, John SE, Channanath A, Iqbal R, Pitkaniemi J, Tuomilehto J, Sladek R, Al-Mulla F, Thanaraj TA. Genome-wide landscape establishes novel association signals for metabolic traits in the Arab population. Human Genetics. PMID 32902719 DOI: 10.1007/S00439-020-02222-7  0.305
2020 Jamal MH, Abu-Farha M, Al-Khaledi G, Al-Sabah S, Ali H, Cherian P, Al-Khairi I, AlOtaibi F, Al-Ali W, Bosso M, Dsouza C, Abubaker J, Al-Mulla F. Effect of sleeve gastrectomy on the expression of meteorin-like (METRNL) and Irisin (FNDC5) in muscle and brown adipose tissue and its impact on uncoupling proteins in diet-induced obesity rats. Surgery For Obesity and Related Diseases : Official Journal of the American Society For Bariatric Surgery. PMID 32861644 DOI: 10.1016/J.Soard.2020.07.022  0.41
2020 Abdel-Halim SM, Al Madhoun A, Nizam R, Melhem M, Cherian P, Al-Khairi I, Haddad D, Abu-Farha M, Abubaker J, Bitar MS, Al-Mulla F. Increased Plasma Levels of Adenylate Cyclase 8 and cAMP Are Associated with Obesity and Type 2 Diabetes: Results from a Cross-Sectional Study. Biology. 9. PMID 32847122 DOI: 10.3390/Biology9090244  0.383
2020 Hammad MM, Abu-Farha M, Hebbar P, Cherian P, Al Khairi I, Melhem M, Alkayal F, Alsmadi O, Thanaraj TA, Al-Mulla F, Abubaker J. Variant rs17782313 Associates With Increased Levels of DNAJC27, Ghrelin, and Visfatin and Correlates With Obesity and Hypertension in a Kuwaiti Cohort. Frontiers in Endocrinology. 11: 437. PMID 32733386 DOI: 10.3389/Fendo.2020.00437  0.382
2020 Hammad MM, Abu-Farha M, Al-Taiar A, Alam-Eldin N, Al-Sabah R, Shaban L, Al-Mulla F, Abubaker J, Rahman A. Correlation of circulating ANGPTL5 levels with obesity, high sensitivity C-reactive protein and oxidized low-density lipoprotein in adolescents. Scientific Reports. 10: 6330. PMID 32286392 DOI: 10.1038/S41598-020-63076-7  0.396
2020 Qaddoumi MG, Alanbaei M, Hammad MM, Al Khairi I, Cherian P, Channanath A, Thanaraj TA, Al-Mulla F, Abu-Farha M, Abubaker J. Investigating the Role of Myeloperoxidase and Angiopoietin-like Protein 6 in Obesity and Diabetes. Scientific Reports. 10: 6170. PMID 32277104 DOI: 10.1038/S41598-020-63149-7  0.408
2019 Hebbar P, Abu-Farha M, Mohammad A, Alkayal F, Melhem M, Abubaker J, Al-Mulla F, Thanaraj TA. Variant rs1421085 Associates With Increased Body Weight, Soft Lean Mass, and Total Body Water Through Interaction With Ghrelin and Apolipoproteins in Arab Population. Frontiers in Genetics. 10: 1411. PMID 32076432 DOI: 10.3389/Fgene.2019.01411  0.342
2019 Al Shawaf E, Abu-Farha M, Devarajan S, Alsairafi Z, Al-Khairi I, Cherian P, Ali H, Mathur A, Al-Mulla F, Al Attar A, Abubaker J. ANGPTL4: A Predictive Marker for Diabetic Nephropathy. Journal of Diabetes Research. 2019: 4943191. PMID 31772941 DOI: 10.1155/2019/4943191  0.357
2019 Sindhu S, Thomas R, Kochumon S, Wilson A, Abu-Farha M, Bennakhi A, Al-Mulla F, Ahmad R. Increased Adipose Tissue Expression of Interferon Regulatory Factor (IRF)-5 in Obesity: Association with Metabolic Inflammation. Cells. 8. PMID 31718015 DOI: 10.3390/Cells8111418  0.381
2019 AlKhairi I, Cherian P, Abu-Farha M, Madhoun AA, Nizam R, Melhem M, Jamal M, Al-Sabah S, Ali H, Tuomilehto J, Al-Mulla F, Abubaker J. Increased Expression of Meteorin-Like Hormone in Type 2 Diabetes and Obesity and Its Association with Irisin. Cells. 8. PMID 31635130 DOI: 10.3390/Cells8101283  0.421
2019 Abu-Farha M, Cherian P, Al-Khairi I, Nizam R, Alkandari A, Arefanian H, Tuomilehto J, Al-Mulla F, Abubaker J. Reduced miR-181d level in obesity and its role in lipid metabolism via regulation of ANGPTL3. Scientific Reports. 9: 11866. PMID 31413305 DOI: 10.1038/S41598-019-48371-2  0.346
2019 Alghanim G, Qaddoumi MG, Alhasawi N, Cherian P, Al-Khairi I, Nizam R, Alkayal F, Alanbaei M, Tuomilehto J, Abubaker J, Abu-Farha M, Al-Mulla F. Higher Levels of ANGPTL5 in the Circulation of Subjects With Obesity and Type 2 Diabetes Are Associated With Insulin Resistance. Frontiers in Endocrinology. 10: 495. PMID 31396158 DOI: 10.3389/Fendo.2019.00495  0.401
2019 Al-Temaimi R, Cherian P, Abu-Farha M, Alroughani R. Angiopoietin-like proteins in multiple sclerosis. Journal of Neuroimmunology. 330: 31-34. PMID 30784773 DOI: 10.1016/J.Jneuroim.2019.02.006  0.302
2019 Abu-Farha M, Cherian PT, Khairi IA, Jamal M, Al-Sabah S, Ali H, Dsouza C, Alotaibi FK, Al-Ali W, Al-Khaledi GM, Abubaker J, Al-Mulla F. 312-LB: Irisin, Meteorin-Like Protein, and Bone Remodeling Markers in T2D and Obesity Diabetes. 68. DOI: 10.2337/Db19-312-Lb  0.377
2019 Qaddoumi MG, Abu-Farha M, Cherian PT, Khairi IA, Channanath AM, Alanbaei M, Abubaker J, Al-Mulla F. 268-LB: Investigating the Role of MPO and ANGPTL6 in Obesity and Diabetes and Their Potential Role in Wound Healing Diabetes. 68. DOI: 10.2337/Db19-268-Lb  0.396
2019 Abu-Farha M, Cherian PT, Khairi IA, Al-Mulla F, Abubaker J. 1871-P: Mir 103/107 Regulates Lipid Metabolism by Inhibiting Betatrophin/ANGPTL8 Diabetes. 68. DOI: 10.2337/Db19-1871-P  0.315
2018 Kochumon S, Al-Rashed F, Abu-Farha M, Devarajan S, Tuomilehto J, Ahmad R. Adipose tissue expression of CCL19 is positively associated with insulin resistance. Diabetes/Metabolism Research and Reviews. e3087. PMID 30339734 DOI: 10.1002/Dmrr.3087  0.346
2018 Cherian PT, Al-Khairi I, Sriraman D, Al-Enezi A, Al-Sultan D, AlOtaibi M, Al-Enezi S, Tuomilehto J, Al-Mulla F, Abubaker JA, Abu-Farha M. Increased Circulation and Adipose Tissue Levels of DNAJC27/RBJ in Obesity and Type 2-Diabetes. Frontiers in Endocrinology. 9: 423. PMID 30131766 DOI: 10.3389/Fendo.2018.00423  0.425
2018 Abu-Farha M, Cherian P, Qaddoumi MG, AlKhairi I, Sriraman D, Alanbaei M, Abubaker J. Increased plasma and adipose tissue levels of ANGPTL8/Betatrophin and ANGPTL4 in people with hypertension. Lipids in Health and Disease. 17: 35. PMID 29490644 DOI: 10.1186/S12944-018-0681-0  0.342
2018 Abu-Farha M, Alhasawi N, Qaddoumi M, Almulla F, Tuomilehto J, Alanbaei M, Abubaker J. Elevated ANGPTL5 Level in the Circulation of Obese and Type 2 Diabetic People Diabetes. 67. DOI: 10.2337/Db18-301-Lb  0.364
2017 Abu-Farha M, Abubaker J, Tuomilehto J. ANGPTL8 (Betatrophin) Role in Diabetes and Metabolic Diseases. Diabetes/Metabolism Research and Reviews. PMID 28722798 DOI: 10.1002/Dmrr.2919  0.394
2017 Abu-Farha M, Cherian P, Al-Khairi I, Madhu D, Tiss A, Warsam S, Alhubail A, Sriraman D, Al-Refaei F, Abubaker J. Plasma and adipose tissue level of angiopoietin-like 7 (ANGPTL7) are increased in obesity and reduced after physical exercise. Plos One. 12: e0173024. PMID 28264047 DOI: 10.1371/Journal.Pone.0173024  0.422
2016 Abu-Farha M, Al-Khairi I, Cherian P, Chandy B, Sriraman D, Alhubail A, Al-Refaei F, AlTerki A, Abubaker J. Increased ANGPTL3, 4 and ANGPTL8/betatrophin expression levels in obesity and T2D. Lipids in Health and Disease. 15: 181. PMID 27733177 DOI: 10.1186/S12944-016-0337-X  0.405
2016 Khadir A, Kavalakatt S, Abubaker J, Cherian P, Madhu D, Al-Khairi I, Abu-Farha M, Warsame S, Elkum N, Dehbi M, Tiss A. Physical exercise alleviates ER stress in obese humans through reduction in the expression and release of GRP78 chaperone. Metabolism: Clinical and Experimental. 65: 1409-20. PMID 27506747 DOI: 10.1016/J.Metabol.2016.06.004  0.388
2016 Baothman OA, Zamzami MA, Taher I, Abubaker J, Abu-Farha M. The role of Gut Microbiota in the development of obesity and Diabetes. Lipids in Health and Disease. 15: 108. PMID 27317359 DOI: 10.1186/S12944-016-0278-4  0.378
2016 Abu-Farha M, Melhem M, Abubaker J, Behbehani K, Alsmadi O, Elkum N. ANGPTL8/Betatrophin R59W variant is associated with higher glucose level in non-diabetic Arabs living in Kuwaits. Lipids in Health and Disease. 15: 26. PMID 26864934 DOI: 10.1186/S12944-016-0195-6  0.314
2016 Abu-Farha M, Abubaker J, Al-Khairi I, Cherian P, Noronha F, Kavalakatt S, Khadir A, Behbehani K, Alarouj M, Bennakhi A, Elkum N. Circulating angiopoietin-like protein 8 (betatrophin) association with HsCRP and metabolic syndrome. Cardiovascular Diabetology. 15: 25. PMID 26850725 DOI: 10.1186/S12933-016-0346-0  0.366
2016 Abu-Farha M, Sriraman D, Cherian P, AlKhairi I, Elkum N, Behbehani K, Abubaker J. Circulating ANGPTL8/Betatrophin Is Increased in Obesity and Reduced after Exercise Training. Plos One. 11: e0147367. PMID 26784326 DOI: 10.1371/Journal.Pone.0147367  0.368
2015 Abu-Farha M, Cherian P, Al-Khairi I, Tiss A, Khadir A, Kavalakatt S, Warsame S, Dehbi M, Behbehani K, Abubaker J. DNAJB3/HSP-40 cochaperone improves insulin signaling and enhances glucose uptake in vitro through JNK repression. Scientific Reports. 5: 14448. PMID 26400768 DOI: 10.1038/Srep14448  0.365
2015 Abu-Farha M, Abubaker J, Al-Khairi I, Cherian P, Noronha F, Hu FB, Behbehani K, Elkum N. Higher plasma betatrophin/ANGPTL8 level in Type 2 Diabetes subjects does not correlate with blood glucose or insulin resistance. Scientific Reports. 5: 10949. PMID 26077345 DOI: 10.1038/Srep10949  0.337
2015 Khadir A, Tiss A, Abubaker J, Abu-Farha M, Al-Khairi I, Cherian P, John J, Kavalakatt S, Warsame S, Al-Madhoun A, Al-Ghimlas F, Elkum N, Behbehani K, Dermime S, Dehbi M. MAP kinase phosphatase DUSP1 is overexpressed in obese humans and modulated by physical exercise. American Journal of Physiology. Endocrinology and Metabolism. 308: E71-83. PMID 25370852 DOI: 10.1152/Ajpendo.00577.2013  0.4
2014 Tiss A, Khadir A, Abubaker J, Abu-Farha M, Al-Khairi I, Cherian P, John J, Kavalakatt S, Warsame S, Al-Ghimlas F, Elkum N, Behbehani K, Dermime S, Dehbi M. Immunohistochemical profiling of the heat shock response in obese non-diabetic subjects revealed impaired expression of heat shock proteins in the adipose tissue. Lipids in Health and Disease. 13: 106. PMID 24986468 DOI: 10.1186/1476-511X-13-106  0.408
2014 Baturcam E, Abubaker J, Tiss A, Abu-Farha M, Khadir A, Al-Ghimlas F, Al-Khairi I, Cherian P, Elkum N, Hammad M, John J, Kavalakatt S, Lehe C, Warsame S, Behbehani K, et al. Physical exercise reduces the expression of RANTES and its CCR5 receptor in the adipose tissue of obese humans. Mediators of Inflammation. 2014: 627150. PMID 24895488 DOI: 10.1155/2014/627150  0.373
2014 Abu-Farha M, Behbehani K, Elkum N. Comprehensive analysis of circulating adipokines and hsCRP association with cardiovascular disease risk factors and metabolic syndrome in Arabs. Cardiovascular Diabetology. 13: 76. PMID 24716628 DOI: 10.1186/1475-2840-13-76  0.3
2014 Khadir A, Tiss A, Abubaker J, Abu-farha M, Dermime S, Dehbi M. Overexpression of the cancer-related DUSP1 gene in human obesity and its modulation by physical exercise Journal For Immunotherapy of Cancer. 2: 5. DOI: 10.1186/2051-1426-2-S1-P5  0.38
2013 Abu-Farha M, Tiss A, Abubaker J, Khadir A, Al-Ghimlas F, Al-Khairi I, Baturcam E, Cherian P, Elkum N, Hammad M, John J, Kavalakatt S, Warsame S, Behbehani K, Dermime S, et al. Proteomics analysis of human obesity reveals the epigenetic factor HDAC4 as a potential target for obesity. Plos One. 8: e75342. PMID 24086512 DOI: 10.1371/Journal.Pone.0075342  0.423
2013 Abubaker J, Tiss A, Abu-Farha M, Al-Ghimlas F, Al-Khairi I, Baturcam E, Cherian P, Elkum N, Hammad M, John J, Kavalakatt S, Khadir A, Warsame S, Dermime S, Behbehani K, et al. DNAJB3/HSP-40 cochaperone is downregulated in obese humans and is restored by physical exercise. Plos One. 8: e69217. PMID 23894433 DOI: 10.1371/Journal.Pone.0069217  0.415
2012 Zhou H, Ning Z, Starr AE, Abu-Farha M, Figeys D. Advancements in top-down proteomics. Analytical Chemistry. 84: 720-34. PMID 22047528 DOI: 10.1021/Ac202882Y  0.502
2012 Abubakr J, Abu-Farha M, Al-Arouj M, Al-Ghimlas F, Al-Khairi I, Al-Mudhaf D, Baturcam E, Bennakhi A, Cherian P, Hammad M, John J, Kavalakatt S, Khadir A, Tiss A, Warsame S, et al. Association of obesity with down-regulation of heat shock protein 40 expression and evidence that exercise retrieves its normal expression Bmc Proceedings. 6: 1-2. DOI: 10.1186/1753-6561-6-S3-P1  0.336
2012 Baturcam E, Abubakr J, Abu-Farha M, Al-Arouj M, Al-Ghimlas F, Al-Khairi I, Al-Mass A, Al-Mudhaf D, Bennakhi A, Cherian P, Hammad M, John J, Kavalakatt S, Khadir A, Tiss A, et al. P042 Multiplexed analysis of inflammatory, metabolic and stress markers in obese subjects before and after a defined exercise program Cytokine. 59: 532. DOI: 10.1016/J.Cyto.2012.06.126  0.397
2011 Abu-Farha M, Lanouette S, Elisma F, Tremblay V, Butson J, Figeys D, Couture JF. Proteomic analyses of the SMYD family interactomes identify HSP90 as a novel target for SMYD2. Journal of Molecular Cell Biology. 3: 301-8. PMID 22028380 DOI: 10.1093/Jmcb/Mjr025  0.529
2011 Ning Z, Zhou H, Wang F, Abu-Farha M, Figeys D. Analytical aspects of proteomics: 2009-2010. Analytical Chemistry. 83: 4407-26. PMID 21491952 DOI: 10.1021/Ac200857T  0.494
2009 Abu-Farha M, Elisma F, Zhou H, Tian R, Zhou H, Asmer MS, Figeys D. Proteomics: from technology developments to biological applications. Analytical Chemistry. 81: 4585-99. PMID 19371061 DOI: 10.1021/Ac900735J  0.474
2008 Abu-Farha M, Elisma F, Figeys D. Identification of protein-protein interactions by mass spectrometry coupled techniques. Advances in Biochemical Engineering/Biotechnology. 110: 67-80. PMID 18227982 DOI: 10.1007/10_2007_091  0.526
2008 Abu-Farha M, Lambert JP, Al-Madhoun AS, Elisma F, Skerjanc IS, Figeys D. The tale of two domains: proteomics and genomics analysis of SMYD2, a new histone methyltransferase. Molecular & Cellular Proteomics : McP. 7: 560-72. PMID 18065756 DOI: 10.1074/Mcp.M700271-Mcp200  0.512
2007 Ewing RM, Chu P, Elisma F, Li H, Taylor P, Climie S, McBroom-Cerajewski L, Robinson MD, O'Connor L, Li M, Taylor R, Dharsee M, Ho Y, Heilbut A, Moore L, ... ... Abu-Farha M, et al. Large-scale mapping of human protein-protein interactions by mass spectrometry. Molecular Systems Biology. 3: 89. PMID 17353931 DOI: 10.1038/Msb4100134  0.532
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