Sachin Patel, M.D., Ph.D. - Publications

Affiliations: 
Vanderbilt University, Nashville, TN 

67 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Kingsley PJ, Rouzer CA, Morgan AJ, Patel S, Marnett LJ. Aspects of Prostaglandin Glycerol Ester Biology. Advances in Experimental Medicine and Biology. 1161: 77-88. PMID 31562623 DOI: 10.1007/978-3-030-21735-8_8  0.68
2019 Morgan A, Kondev V, Bedse G, Baldi R, Marcus D, Patel S. Cyclooxygenase-2 inhibition reduces anxiety-like behavior and normalizes enhanced amygdala glutamatergic transmission following chronic oral corticosterone treatment. Neurobiology of Stress. 11: 100190. PMID 31467944 DOI: 10.1016/j.ynstr.2019.100190  0.76
2019 Centanni SW, Bedse G, Patel S, Winder DG. Driving the Downward Spiral: Alcohol-Induced Dysregulation of Extended Amygdala Circuits and Negative Affect. Alcoholism, Clinical and Experimental Research. PMID 31403699 DOI: 10.1111/acer.14178  0.92
2019 Bedse G, Centanni SW, Winder DG, Patel S. Endocannabinoid Signaling in the Central Amygdala and Bed Nucleus of the Stria Terminalis: Implications for the Pathophysiology and Treatment of Alcohol Use Disorder. Alcoholism, Clinical and Experimental Research. PMID 31373708 DOI: 10.1111/acer.14159  0.92
2018 Bruehl S, Burns JW, Morgan A, Koltyn K, Gupta R, Buvanendran A, Edwards D, Chont M, Kingsley PJ, Marnett L, Stone A, Patel S. The association between endogenous opioid function and morphine responsiveness: a moderating role for endocannabinoids. Pain. PMID 30562268 DOI: 10.1097/j.pain.0000000000001447  0.64
2018 Centanni SW, Morris BD, Luchsinger JR, Bedse G, Fetterly TL, Patel S, Winder DG. Endocannabinoid control of the insular-bed nucleus of the stria terminalis circuit regulates negative affective behavior associated with alcohol abstinence. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 30390064 DOI: 10.1038/s41386-018-0257-8  0.92
2018 Cavener VS, Gaulden A, Pennipede D, Jagasia P, Uddin J, Marnett LJ, Patel S. Inhibition of Diacylglycerol Lipase Impairs Fear Extinction in Mice. Frontiers in Neuroscience. 12: 479. PMID 30108473 DOI: 10.3389/fnins.2018.00479  0.68
2018 Morgan A, Kingsley PJ, Mitchener MM, Altemus M, Patrick T, Gaulden A, Marnett LJ, Patel S. Detection of cyclooxygenase-2-derived oxygenation products of the endogenous cannabinoid 2-arachidonoylglycerol in mouse brain. Acs Chemical Neuroscience. PMID 29722963 DOI: 10.1021/acschemneuro.7b00499  0.68
2018 Bedse G, Bluett RJ, Patrick TA, Romness NK, Gaulden AD, Kingsley PJ, Plath N, Marnett LJ, Patel S. Therapeutic endocannabinoid augmentation for mood and anxiety disorders: comparative profiling of FAAH, MAGL and dual inhibitors. Translational Psychiatry. 8: 92. PMID 29695817 DOI: 10.1038/s41398-018-0141-7  0.8
2018 Wenzel JM, Oleson EB, Gove WN, Cole AB, Gyawali U, Dantrassy HM, Bluett RJ, Dryanovski DI, Stuber GD, Deisseroth K, Mathur BN, Patel S, Lupica CR, Cheer JF. Phasic Dopamine Signals in the Nucleus Accumbens that Cause Active Avoidance Require Endocannabinoid Mobilization in the Midbrain. Current Biology : Cb. PMID 29681476 DOI: 10.1016/j.cub.2018.03.037  0.8
2017 Shonesy BC, Parrish WP, Haddad HK, Stephenson JR, Báldi R, Bluett RJ, Marks CR, Centanni SW, Folkes OM, Spiess K, Augustin SM, Mackie K, Lovinger DM, Winder DG, Patel S, et al. Role of Striatal Direct Pathway 2-Arachidonoylglycerol Signaling in Sociability and Repetitive Behavior. Biological Psychiatry. PMID 29458998 DOI: 10.1016/j.biopsych.2017.11.036  0.92
2017 Hill MN, Campolongo P, Yehuda R, Patel S. Integrating Endocannabinoid Signaling and Cannabinoids into the Biology and Treatment of Posttraumatic Stress Disorder. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 28745306 DOI: 10.1038/npp.2017.162  0.92
2017 Bedse G, Hartley ND, Neale E, Gaulden AD, Patrick TA, Kingsley PJ, Uddin MJ, Plath N, Marnett LJ, Patel S. Functional Redundancy Between Canonical Endocannabinoid Signaling Systems in the Modulation of Anxiety. Biological Psychiatry. PMID 28438413 DOI: 10.1016/j.biopsych.2017.03.002  0.76
2017 Patel S, Hill MN, Cheer JF, Wotjak CT, Holmes A. The endocannabinoid system as a target for novel anxiolytic drugs. Neuroscience and Biobehavioral Reviews. 76: 56-66. PMID 28434588 DOI: 10.1016/j.neubiorev.2016.12.033  0.92
2017 Bluett RJ, Báldi R, Haymer A, Gaulden AD, Hartley ND, Parrish WP, Baechle J, Marcus DJ, Mardam-Bey R, Shonesy BC, Uddin MJ, Marnett LJ, Mackie K, Colbran RJ, Winder DG, ... Patel S, et al. Endocannabinoid signalling modulates susceptibility to traumatic stress exposure. Nature Communications. 8: 14782. PMID 28348378 DOI: 10.1038/ncomms14782  0.92
2016 Foster DJ, Wilson JM, Remke DH, Mahmood MS, Uddin MJ, Wess J, Patel S, Marnett LJ, Niswender CM, Jones CK, Xiang Z, Lindsley CW, Rook JM, Conn PJ. Antipsychotic-like Effects of M4 Positive Allosteric Modulators Are Mediated by CB2 Receptor-Dependent Inhibition of Dopamine Release. Neuron. PMID 27618677 DOI: 10.1016/j.neuron.2016.08.017  0.92
2016 Gamble-George JC, Baldi R, Halladay L, Kocharian A, Hartley N, Silva CG, Roberts H, Haymer A, Marnett LJ, Holmes A, Patel S. Cyclooxygenase-2 inhibition reduces stress-induced affective pathology. Elife. 5. PMID 27162170 DOI: 10.7554/eLife.14137  0.68
2016 Báldi R, Ghosh D, Grueter BA, Patel S. Electrophysiological Measurement of Cannabinoid-Mediated Synaptic Modulation in Acute Mouse Brain Slices. Current Protocols in Neuroscience / Editorial Board, Jacqueline N. Crawley ... [Et Al.]. 75: 6.29.1-6.29.19. PMID 27063786 DOI: 10.1002/cpns.8  0.84
2016 Gray JM, Wilson CD, Lee TT, Pittman QJ, Deussing JM, Hillard CJ, McEwen BS, Schulkin J, Karatsoreos IN, Patel S, Hill MN. Sustained glucocorticoid exposure recruits cortico-limbic CRH signaling to modulate endocannabinoid function. Psychoneuroendocrinology. 66: 151-158. PMID 26821211 DOI: 10.1016/j.psyneuen.2016.01.004  0.92
2016 Holleran KM, Wilson HH, Fetterly TL, Bluett RJ, Centanni SW, Gilfarb RA, Rocco LE, Patel S, Winder DG. Ketamine and MAG Lipase Inhibitor-Dependent Reversal of Evolving Depressive Behavior during Forced Abstinence from Alcohol Drinking. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 26751284 DOI: 10.1038/npp.2016.3  0.8
2015 Robinson SL, Alexander NJ, Bluett RJ, Patel S, McCool BA. Acute and Chronic Ethanol Exposure Differentially Regulate CB1 Receptor Function at Glutamatergic Synapses in the Rat Basolateral Amygdala. Neuropharmacology. PMID 26707595 DOI: 10.1016/j.neuropharm.2015.12.005  0.92
2015 Gunduz-Cinar O, Flynn S, Brockway E, Kaugars K, Baldi R, Ramikie TS, Cinar R, Kunos G, Patel S, Holmes A. Fluoxetine Facilitates Fear Extinction through Amygdala Endocannabinoids. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 26514583 DOI: 10.1038/npp.2015.318  0.92
2015 Bukalo O, Pinard CR, Silverstein S, Brehm C, Hartley ND, Whittle N, Colacicco G, Busch E, Patel S, Singewald N, Holmes A. Prefrontal inputs to the amygdala instruct fear extinction memory formation. Science Advances. 1. PMID 26504902 DOI: 10.1126/sciadv.1500251  0.6
2015 Patel S, Shonesy BC, Bluett RJ, Winder DG, Colbran RJ. The Anxiolytic Actions of 2-Arachidonoylglycerol: Converging Evidence from Two Recent Genetic Endocannabinoid Deficiency Models. Biological Psychiatry. PMID 26212898 DOI: 10.1016/j.biopsych.2015.04.028  0.92
2015 Morena M, Patel S, Bains JS, Hill MN. Neurobiological Interactions Between Stress and the Endocannabinoid System. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 26068727 DOI: 10.1038/npp.2015.166  0.92
2015 Gray JM, Vecchiarelli HA, Morena M, Lee TT, Hermanson DJ, Kim AB, McLaughlin RJ, Hassan KI, Kühne C, Wotjak CT, Deussing JM, Patel S, Hill MN. Corticotropin-releasing hormone drives anandamide hydrolysis in the amygdala to promote anxiety. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 3879-92. PMID 25740517 DOI: 10.1523/JNEUROSCI.2737-14.2015  0.92
2015 Patel S, Cone RD. Neuroscience: a cellular basis for the munchies. Nature. 519: 38-40. PMID 25707800 DOI: 10.1038/nature14206  0.92
2015 Shonesy BC, Winder DG, Patel S, Colbran RJ. The initiation of synaptic 2-AG mobilization requires both an increased supply of diacylglycerol precursor and increased postsynaptic calcium. Neuropharmacology. 91: 57-62. PMID 25484252 DOI: 10.1016/j.neuropharm.2014.11.026  0.92
2014 Shonesy BC, Bluett RJ, Ramikie TS, Báldi R, Hermanson DJ, Kingsley PJ, Marnett LJ, Winder DG, Colbran RJ, Patel S. Genetic disruption of 2-arachidonoylglycerol synthesis reveals a key role for endocannabinoid signaling in anxiety modulation. Cell Reports. 9: 1644-53. PMID 25466252 DOI: 10.1016/j.celrep.2014.11.001  0.92
2014 Tchantchou F, Tucker LB, Fu AH, Bluett RJ, McCabe JT, Patel S, Zhang Y. The fatty acid amide hydrolase inhibitor PF-3845 promotes neuronal survival, attenuates inflammation and improves functional recovery in mice with traumatic brain injury. Neuropharmacology. 85: 427-39. PMID 24937045 DOI: 10.1016/j.neuropharm.2014.06.006  0.92
2014 Hermanson DJ, Gamble-George JC, Marnett LJ, Patel S. Substrate-selective COX-2 inhibition as a novel strategy for therapeutic endocannabinoid augmentation. Trends in Pharmacological Sciences. 35: 358-67. PMID 24845457 DOI: 10.1016/j.tips.2014.04.006  0.92
2014 Ramikie TS, Nyilas R, Bluett RJ, Gamble-George JC, Hartley ND, Mackie K, Watanabe M, Katona I, Patel S. Multiple mechanistically distinct modes of endocannabinoid mobilization at central amygdala glutamatergic synapses. Neuron. 81: 1111-25. PMID 24607231 DOI: 10.1016/j.neuron.2014.01.012  0.92
2014 Hamza B, Wong E, Patel S, Cho H, Martel J, Irimia D. Retrotaxis of human neutrophils during mechanical confinement inside microfluidic channels. Integrative Biology : Quantitative Biosciences From Nano to Macro. 6: 175-83. PMID 24419464 DOI: 10.1039/c3ib40175h  0.92
2013 Hill MN, Patel S. Translational evidence for the involvement of the endocannabinoid system in stress-related psychiatric illnesses. Biology of Mood & Anxiety Disorders. 3: 19. PMID 24286185 DOI: 10.1186/2045-5380-3-19  0.92
2013 Hermanson DJ, Hartley ND, Gamble-George J, Brown N, Shonesy BC, Kingsley PJ, Colbran RJ, Reese J, Marnett LJ, Patel S. Substrate-selective COX-2 inhibition decreases anxiety via endocannabinoid activation. Nature Neuroscience. 16: 1291-8. PMID 23912944 DOI: 10.1038/nn.3480  0.92
2013 Shonesy BC, Wang X, Rose KL, Ramikie TS, Cavener VS, Rentz T, Baucum AJ, Jalan-Sakrikar N, Mackie K, Winder DG, Patel S, Colbran RJ. CaMKII regulates diacylglycerol lipase-α and striatal endocannabinoid signaling. Nature Neuroscience. 16: 456-63. PMID 23502535 DOI: 10.1038/nn.3353  0.92
2013 Gamble-George JC, Conger JR, Hartley ND, Gupta P, Sumislawski JJ, Patel S. Dissociable effects of CB1 receptor blockade on anxiety-like and consummatory behaviors in the novelty-induced hypophagia test in mice. Psychopharmacology. 228: 401-9. PMID 23483200 DOI: 10.1007/s00213-013-3042-8  0.92
2012 Patel S. High times for low-frequency stimulation as endocannabinoids engage in hippocampal long-term depression. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 37: 583-5. PMID 22240538 DOI: 10.1038/npp.2011.275  0.92
2012 Patil SD, Patel MR, Patel SR, Surana SJ. Amaranthus spinosus Linn. inhibits mast cell-mediated anaphylactic reactions. Journal of Immunotoxicology. 9: 77-84. PMID 22145857 DOI: 10.3109/1547691X.2011.631609  0.92
2011 Sumislawski JJ, Ramikie TS, Patel S. Reversible gating of endocannabinoid plasticity in the amygdala by chronic stress: a potential role for monoacylglycerol lipase inhibition in the prevention of stress-induced behavioral adaptation. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 36: 2750-61. PMID 21849983 DOI: 10.1038/npp.2011.166  0.92
2010 Patel S, Winder DG. An odyssey of fear: Homer stresses new mechanisms. Biological Psychiatry. 68: 980-1. PMID 21075227 DOI: 10.1016/j.biopsych.2010.10.005  0.92
2010 Hill MN, Patel S, Campolongo P, Tasker JG, Wotjak CT, Bains JS. Functional interactions between stress and the endocannabinoid system: from synaptic signaling to behavioral output. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 14980-6. PMID 21068301 DOI: 10.1523/JNEUROSCI.4283-10.2010  0.92
2010 Mozhui K, Karlsson RM, Kash TL, Ihne J, Norcross M, Patel S, Farrell MR, Hill EE, Graybeal C, Martin KP, Camp M, Fitzgerald PJ, Ciobanu DC, Sprengel R, Mishina M, et al. Strain differences in stress responsivity are associated with divergent amygdala gene expression and glutamate-mediated neuronal excitability. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 5357-67. PMID 20392957 DOI: 10.1523/JNEUROSCI.5017-09.2010  0.92
2010 McElligott ZA, Klug JR, Nobis WP, Patel S, Grueter BA, Kash TL, Winder DG. Distinct forms of Gq-receptor-dependent plasticity of excitatory transmission in the BNST are differentially affected by stress. Proceedings of the National Academy of Sciences of the United States of America. 107: 2271-6. PMID 20133871 DOI: 10.1073/pnas.0905568107  0.92
2009 Patel S, Hillard CJ. Role of endocannabinoid signaling in anxiety and depression. Current Topics in Behavioral Neurosciences. 1: 347-71. PMID 21104391 DOI: 10.1007/978-3-540-88955-7_14  0.92
2009 Hill MN, Hillard CJ, Bambico FR, Patel S, Gorzalka BB, Gobbi G. The therapeutic potential of the endocannabinoid system for the development of a novel class of antidepressants. Trends in Pharmacological Sciences. 30: 484-93. PMID 19732971 DOI: 10.1016/j.tips.2009.06.006  0.92
2009 Patel S, Kingsley PJ, Mackie K, Marnett LJ, Winder DG. Repeated homotypic stress elevates 2-arachidonoylglycerol levels and enhances short-term endocannabinoid signaling at inhibitory synapses in basolateral amygdala. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 34: 2699-709. PMID 19675536 DOI: 10.1038/npp.2009.101  0.92
2008 Patel S, Hillard CJ. Adaptations in endocannabinoid signaling in response to repeated homotypic stress: a novel mechanism for stress habituation. The European Journal of Neuroscience. 27: 2821-9. PMID 18588527 DOI: 10.1111/j.1460-9568.2008.06266.x  0.92
2008 Hill MN, Carrier EJ, Ho WS, Shi L, Patel S, Gorzalka BB, Hillard CJ. Prolonged glucocorticoid treatment decreases cannabinoid CB1 receptor density in the hippocampus. Hippocampus. 18: 221-6. PMID 18058925 DOI: 10.1002/hipo.20386  0.92
2006 Patel S, Benaknin J, Tsao C. Ritualistic excoriation and blood-letting resulting in anemia in borderline personality disorder. General Hospital Psychiatry. 28: 539-40. PMID 17088171 DOI: 10.1016/j.genhosppsych.2006.07.008  0.92
2006 Patel S, Hillard CJ. Pharmacological evaluation of cannabinoid receptor ligands in a mouse model of anxiety: further evidence for an anxiolytic role for endogenous cannabinoid signaling. The Journal of Pharmacology and Experimental Therapeutics. 318: 304-11. PMID 16569753 DOI: 10.1124/jpet.106.101287  0.92
2005 Patel S, Roelke CT, Rademacher DJ, Hillard CJ. Inhibition of restraint stress-induced neural and behavioural activation by endogenous cannabinoid signalling. The European Journal of Neuroscience. 21: 1057-69. PMID 15787710 DOI: 10.1111/j.1460-9568.2005.03916.x  0.92
2005 Rademacher DJ, Patel S, Ho WS, Savoie AM, Rusch NJ, Gauthier KM, Hillard CJ. U-46619 but not serotonin increases endocannabinoid content in middle cerebral artery: evidence for functional relevance. American Journal of Physiology. Heart and Circulatory Physiology. 288: H2694-701. PMID 15695564 DOI: 10.1152/ajpheart.00978.2004  0.92
2005 Patel S, Carrier EJ, Ho WS, Rademacher DJ, Cunningham S, Reddy DS, Falck JR, Cravatt BF, Hillard CJ. The postmortal accumulation of brain N-arachidonylethanolamine (anandamide) is dependent upon fatty acid amide hydrolase activity. Journal of Lipid Research. 46: 342-9. PMID 15576840 DOI: 10.1194/jlr.M400377-JLR200  0.92
2005 Hill MN, Patel S, Carrier EJ, Rademacher DJ, Ormerod BK, Hillard CJ, Gorzalka BB. Downregulation of endocannabinoid signaling in the hippocampus following chronic unpredictable stress. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 30: 508-15. PMID 15525997 DOI: 10.1038/sj.npp.1300601  0.92
2005 Patel S, Cravatt BF, Hillard CJ. Synergistic interactions between cannabinoids and environmental stress in the activation of the central amygdala. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 30: 497-507. PMID 15280883 DOI: 10.1038/sj.npp.1300535  0.92
2004 Lu H, Patel S, Luo F, Li SJ, Hillard CJ, Ward BD, Hyde JS. Spatial correlations of laminar BOLD and CBV responses to rat whisker stimulation with neuronal activity localized by Fos expression. Magnetic Resonance in Medicine. 52: 1060-8. PMID 15508149 DOI: 10.1002/mrm.20265  0.92
2004 Patel S, Roelke CT, Rademacher DJ, Cullinan WE, Hillard CJ. Endocannabinoid signaling negatively modulates stress-induced activation of the hypothalamic-pituitary-adrenal axis. Endocrinology. 145: 5431-8. PMID 15331569 DOI: 10.1210/en.2004-0638  0.92
2004 Patel S, Huang DL, Sagher O. Evidence for a central pathway in the cerebrovascular effects of spinal cord stimulation. Neurosurgery. 55: 201-6; discussion 20. PMID 15214990  0.92
2004 Rademacher DJ, Kearn CS, Carrier EJ, Patel S, Delgado MA, Barkmeier A, Klick DE, Breese NM, Pfister SL, Nithipatikom K, Campbell WB, Hillard CJ. Production of hydroxyeicosatetraenoic acids and prostaglandins by a novel rat microglial cell line. Journal of Neuroimmunology. 149: 130-41. PMID 15020073 DOI: 10.1016/j.jneuroim.2003.12.022  0.92
2004 Seagard JL, Dean C, Patel S, Rademacher DJ, Hopp FA, Schmeling WT, Hillard CJ. Anandamide content and interaction of endocannabinoid/GABA modulatory effects in the NTS on baroreflex-evoked sympathoinhibition. American Journal of Physiology. Heart and Circulatory Physiology. 286: H992-1000. PMID 14615281 DOI: 10.1152/ajpheart.00870.2003  0.92
2003 Patel S, Huang DL, Sagher O. Sympathetic mechanisms in cerebral blood flow alterations induced by spinal cord stimulation. Journal of Neurosurgery. 99: 754-61. PMID 14567612 DOI: 10.3171/jns.2003.99.4.0754  0.92
2003 Patel S, Wohlfeil ER, Rademacher DJ, Carrier EJ, Perry LJ, Kundu A, Falck JR, Nithipatikom K, Campbell WB, Hillard CJ. The general anesthetic propofol increases brain N-arachidonylethanolamine (anandamide) content and inhibits fatty acid amide hydrolase. British Journal of Pharmacology. 139: 1005-13. PMID 12839875 DOI: 10.1038/sj.bjp.0705334  0.92
2003 Patel S, Rademacher DJ, Hillard CJ. Differential regulation of the endocannabinoids anandamide and 2-arachidonylglycerol within the limbic forebrain by dopamine receptor activity. The Journal of Pharmacology and Experimental Therapeutics. 306: 880-8. PMID 12808005 DOI: 10.1124/jpet.103.054270  0.92
2003 Patel S, Hillard CJ. Cannabinoid-induced Fos expression within A10 dopaminergic neurons. Brain Research. 963: 15-25. PMID 12560108 DOI: 10.1016/S0006-8993(02)03797-6  0.92
2003 Rademacher DJ, Patel S, Hopp FA, Dean C, Hillard CJ, Seagard JL. Microinjection of a cannabinoid receptor antagonist into the NTS increases baroreflex duration in dogs. American Journal of Physiology. Heart and Circulatory Physiology. 284: H1570-6. PMID 12521935 DOI: 10.1152/ajpheart.00772.2002  0.92
2002 Patel S, Gerrits R, Muthian S, Greene AS, Hillard CJ. The CB1 receptor antagonist SR141716 enhances stimulus-induced activation of the primary somatosensory cortex of the rat. Neuroscience Letters. 335: 95-8. PMID 12459507 DOI: 10.1016/S0304-3940(02)01170-9  0.92
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