Garret A. FitzGerald, M.D. - Publications

University of Pennsylvania, Philadelphia, PA, United States 

277 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Hermida RC, Smolensky MH, Balan H, Castriotta RJ, Crespo JJ, Dagan Y, El-Toukhy S, Fernández JR, FitzGerald GA, Fujimura A, Geng YJ, Hermida-Ayala RG, Machado AP, Menna-Barreto L, Mojón A, et al. Guidelines for the design and conduct of human clinical trials on ingestion-time differences - chronopharmacology and chronotherapy - of hypertension medications. Chronobiology International. 1-26. PMID 33342316 DOI: 10.1080/07420528.2020.1850468  0.56
2020 Lordan R, FitzGerald GA, Grosser T. Reopening schools during COVID-19. Science (New York, N.Y.). 369: 1146. PMID 32883837 DOI: 10.1126/science.abe5765  0.56
2019 Sarantopoulou D, Tang SY, Ricciotti E, Lahens NF, Lekkas D, Schug J, Guo XS, Paschos GK, FitzGerald GA, Pack AI, Grant GR. Comparative evaluation of RNA-Seq library preparation methods for strand-specificity and low input. Scientific Reports. 9: 13477. PMID 31530843 DOI: 10.1038/s41598-019-49889-1  0.72
2019 Ruben MD, Smith DF, FitzGerald GA, Hogenesch JB. Dosing time matters. Science (New York, N.Y.). 365: 547-549. PMID 31395773 DOI: 10.1126/science.aax7621  0.92
2019 Sacco A, Bruno A, Contursi A, Dovizio M, Tacconelli S, Ricciotti E, Guillem-Llobat P, Salvatore T, Di Francesco L, Fullone R, Ballerini P, Arena V, Alberti S, Liu G, Gong Y, ... ... FitzGerald G, et al. Platelet-specific deletion of cyclooxygenase-1 ameliorates dextran sulfate sodium-induced colitis in mice. The Journal of Pharmacology and Experimental Therapeutics. PMID 31248980 DOI: 10.1124/jpet.119.259382  0.52
2019 Markosyan N, Li J, Sun YH, Richman LP, Lin JH, Yan F, Quinones L, Sela Y, Yamazoe T, Gordon N, Tobias JW, Byrne KT, Rech AJ, FitzGerald GA, Stanger BZ, et al. Tumor cell-intrinsic EPHA2 suppresses anti-tumor immunity by regulating PTGS2 (COX-2). The Journal of Clinical Investigation. 130. PMID 31162144 DOI: 10.1172/JCI127755  0.36
2019 Zhu L, Xu C, Huo X, Hao H, Wan Q, Chen H, Zhang X, Breyer RM, Huang Y, Cao X, Liu DP, FitzGerald GA, Wang M. The cyclooxygenase-1/mPGES-1/endothelial prostaglandin EP4 receptor pathway constrains myocardial ischemia-reperfusion injury. Nature Communications. 10: 1888. PMID 31015404 DOI: 10.1038/s41467-019-09492-4  0.52
2019 Chen L, Yang G, Jiang T, Tang SY, Wang T, Wan Q, Wang M, FitzGerald GA. Myeloid cell mPges-1 depletion attenuates mortality without affecting remodeling after acute myocardial infarction in mice. The Journal of Pharmacology and Experimental Therapeutics. PMID 30992314 DOI: 10.1124/jpet.118.256057  0.52
2019 Theken KN, Hersh EV, Lahens NF, Lee HM, Li X, Granquist EJ, Giannakopoulos H, Levin LM, Secreto SA, Grant GR, Detre JA, FitzGerald GA, Grosser T, Farrar JT. Variability in the Analgesic Response to Ibuprofen is Associated with Cyclooxygenase Activation in Inflammatory Pain. Clinical Pharmacology and Therapeutics. PMID 30929268 DOI: 10.1002/cpt.1446  0.56
2018 Song WL, Ricciotti E, Liang X, Grosser T, Grant GR, FitzGerald GA. L-Pgds but not H-Pgds deletion causes hypertension and accelerates thrombogenesis in mice. The Journal of Pharmacology and Experimental Therapeutics. PMID 30305427 DOI: 10.1124/jpet.118.250936  0.56
2018 Paschos GK, Tang SY, Theken KN, Li X, Verginadis I, Lekkas D, Herman L, Yan W, Lawson J, FitzGerald GA. Cold-Induced Browning of Inguinal White Adipose Tissue Is Independent of Adipose Tissue Cyclooxygenase-2. Cell Reports. 24: 809-814. PMID 30044978 DOI: 10.1016/j.celrep.2018.06.082  0.72
2018 Hao H, Hu S, Wan Q, Xu C, Chen H, Zhu L, Xu Z, Meng J, Breyer RM, Li N, Liu DP, FitzGerald GA, Wang M. Protective Role of mPGES-1 (Microsomal Prostaglandin E Synthase-1)-Derived PGE(Prostaglandin E2) and the Endothelial EP4 (Prostaglandin E Receptor) in Vascular Responses to Injury. Arteriosclerosis, Thrombosis, and Vascular Biology. PMID 29599139 DOI: 10.1161/ATVBAHA.118.310713  0.52
2018 Grosser T, Naji A, FitzGerald GA. Urinary Prostaglandin Metabolites: An Incomplete Reckoning and a Flush to Judgment. Circulation Research. 122: 537-539. PMID 29449357 DOI: 10.1161/CIRCRESAHA.118.312616  0.56
2017 Skarke C, Lahens NF, Rhoades SD, Campbell A, Bittinger K, Bailey A, Hoffmann C, Olson RS, Chen L, Yang G, Price TS, Moore JH, Bushman FD, Greene CS, Grant GR, ... ... FitzGerald GA, et al. A Pilot Characterization of the Human Chronobiome. Scientific Reports. 7: 17141. PMID 29215023 DOI: 10.1038/s41598-017-17362-6  0.92
2017 Hughes ME, Abruzzi KC, Allada R, Anafi R, Arpat AB, Asher G, Baldi P, de Bekker C, Bell-Pedersen D, Blau J, Brown S, Ceriani MF, Chen Z, Chiu JC, Cox J, ... ... FitzGerald GA, et al. Guidelines for Genome-Scale Analysis of Biological Rhythms. Journal of Biological Rhythms. 748730417728663. PMID 29098954 DOI: 10.1177/0748730417728663  0.92
2017 Paschos GK, FitzGerald GA. Circadian Clocks and Metabolism: Implications for Microbiome and Aging. Trends in Genetics : Tig. PMID 28844699 DOI: 10.1016/j.tig.2017.07.010  0.72
2017 Grosser T, Theken KN, FitzGerald GA. Cyclooxygenase inhibition: Pain, inflammation and the cardiovascular system. Clinical Pharmacology and Therapeutics. PMID 28710775 DOI: 10.1002/cpt.794  0.56
2017 Grosser T, Ricciotti E, FitzGerald GA. The Cardiovascular Pharmacology of Nonsteroidal Anti-Inflammatory Drugs. Trends in Pharmacological Sciences. PMID 28651847 DOI: 10.1016/  0.56
2017 Grosser T, Woolf CJ, FitzGerald GA. Time for nonaddictive relief of pain. Science (New York, N.Y.). 355: 1026-1027. PMID 28280170 DOI: 10.1126/science.aan0088  0.56
2016 Mazaleuskaya LL, Lawson JA, Li X, Grant G, Mesaros C, Grosser T, Blair IA, Ricciotti E, FitzGerald GA. A broad-spectrum lipidomics screen of antiinflammatory drug combinations in human blood. Jci Insight. 1. PMID 27547824 DOI: 10.1172/jci.insight.87031  0.56
2016 Yang G, Chen L, Grant GR, Paschos G, Song WL, Musiek ES, Lee V, McLoughlin SC, Grosser T, Cotsarelis G, FitzGerald GA. Timing of expression of the core clock gene Bmal1 influences its effects on aging and survival. Science Translational Medicine. 8: 324ra16. PMID 26843191 DOI: 10.1126/scitranslmed.aad3305  0.56
2015 Fitzgerald GA, Yang G, Paschos GK, Liang X, Skarke C. Molecular clocks and the human condition: approaching their characterization in human physiology and disease. Diabetes, Obesity & Metabolism. 17: 139-42. PMID 26332979 DOI: 10.1111/dom.12526  0.72
2015 Skarke C, Alamuddin N, Lawson JA, Li X, Ferguson JF, Reilly MP, FitzGerald GA. Bioactive products formed in humans from fish oils. Journal of Lipid Research. 56: 1808-20. PMID 26180051 DOI: 10.1194/jlr.M060392  1
2015 Curtis AM, Fagundes CT, Yang G, Palsson-McDermott EM, Wochal P, McGettrick AF, Foley NH, Early JO, Chen L, Zhang H, Xue C, Geiger SS, Hokamp K, Reilly MP, Coogan AN, ... ... FitzGerald GA, et al. Circadian control of innate immunity in macrophages by miR-155 targeting Bmal1. Proceedings of the National Academy of Sciences of the United States of America. 112: 7231-6. PMID 25995365 DOI: 10.1073/pnas.1501327112  1
2015 Greene CS, Krishnan A, Wong AK, Ricciotti E, Zelaya RA, Himmelstein DS, Zhang R, Hartmann BM, Zaslavsky E, Sealfon SC, Chasman DI, FitzGerald GA, Dolinski K, Grosser T, Troyanskaya OG. Understanding multicellular function and disease with human tissue-specific networks. Nature Genetics. 47: 569-76. PMID 25915600 DOI: 10.1038/ng.3259  0.56
2015 Castro C, Briggs W, Paschos GK, FitzGerald GA, Griffin JL. A metabolomic study of adipose tissue in mice with a disruption of the circadian system. Molecular Biosystems. 11: 1897-906. PMID 25907923 DOI: 10.1039/c5mb00032g  0.72
2015 McLoughlin SC, Haines P, FitzGerald GA. Clocks and cardiovascular function. Methods in Enzymology. 552: 211-28. PMID 25707279 DOI: 10.1016/bs.mie.2014.11.029  1
2014 Li X, Fries S, Li R, Lawson JA, Propert KJ, Diamond SL, Blair IA, FitzGerald GA, Grosser T. Differential impairment of aspirin-dependent platelet cyclooxygenase acetylation by nonsteroidal antiinflammatory drugs. Proceedings of the National Academy of Sciences of the United States of America. 111: 16830-5. PMID 25385584 DOI: 10.1073/pnas.1406997111  1
2014 Chen L, Yang G, Monslow J, Todd L, Cormode DP, Tang J, Grant GR, DeLong JH, Tang SY, Lawson JA, Pure E, Fitzgerald GA. Myeloid cell microsomal prostaglandin E synthase-1 fosters atherogenesis in mice. Proceedings of the National Academy of Sciences of the United States of America. 111: 6828-33. PMID 24753592 DOI: 10.1073/pnas.1401797111  0.44
2014 Yan S, Zhang Q, Zhong X, Tang J, Wang Y, Yu J, Zhou Y, Zhang J, Guo F, Liu Y, FitzGerald GA, Yu Y. I prostanoid receptor-mediated inflammatory pathway promotes hepatic gluconeogenesis through activation of PKA and inhibition of AKT. Diabetes. 63: 2911-23. PMID 24722246 DOI: 10.2337/db13-1893  0.52
2014 Chen EP, Markosyan N, Connolly E, Lawson JA, Li X, Grant GR, Grosser T, FitzGerald GA, Smyth EM. Myeloid Cell COX-2 deletion reduces mammary tumor growth through enhanced cytotoxic T-lymphocyte function. Carcinogenesis. 35: 1788-97. PMID 24590894 DOI: 10.1093/carcin/bgu053  1
2014 Holmes MV, Lange LA, Palmer T, Lanktree MB, North KE, Almoguera B, Buxbaum S, Chandrupatla HR, Elbers CC, Guo Y, Hoogeveen RC, Li J, Li YR, Swerdlow DI, Cushman M, ... ... FitzGerald GA, et al. Causal effects of body mass index on cardiometabolic traits and events: a Mendelian randomization analysis. American Journal of Human Genetics. 94: 198-208. PMID 24462370 DOI: 10.1016/j.ajhg.2013.12.014  0.92
2014 Daham K, James A, Balgoma D, Kupczyk M, Billing B, Lindeberg A, Henriksson E, FitzGerald GA, Wheelock CE, Dahlén SE, Dahlén B. Effects of selective COX-2 inhibition on allergen-induced bronchoconstriction and airway inflammation in asthma. The Journal of Allergy and Clinical Immunology. 134: 306-13. PMID 24461582 DOI: 10.1016/j.jaci.2013.12.002  1
2013 Paschos GK, FitzGerald GA. Insulin Tolerance Test and Hyperinsulinemic-Euglycemic Clamp. Bio-Protocol. 3. PMID 27446975  0.72
2013 Musiek ES, Lim MM, Yang G, Bauer AQ, Qi L, Lee Y, Roh JH, Ortiz-Gonzalez X, Dearborn JT, Culver JP, Herzog ED, Hogenesch JB, Wozniak DF, Dikranian K, Giasson BI, ... ... Fitzgerald GA, et al. Circadian clock proteins regulate neuronal redox homeostasis and neurodegeneration. The Journal of Clinical Investigation. 123: 5389-400. PMID 24270424 DOI: 10.1172/JCI70317  0.92
2013 Yang G, Paschos G, Curtis AM, Musiek ES, McLoughlin SC, FitzGerald GA. Knitting up the raveled sleave of care. Science Translational Medicine. 5: 212rv3. PMID 24259052 DOI: 10.1126/scitranslmed.3007225  1
2013 Grosser T, Fries S, Lawson JA, Kapoor SC, Grant GR, Fitzgerald GA. Response to letters regarding article, "Drug resistance and pseudoresistance: an unintended consequence of enteric coating aspirin". Circulation. 128: e191. PMID 24043153 DOI: 10.1161/CIRCULATIONAHA.113.004750  1
2013 FitzGerald GA. Anecdotes from ITMAT: building capacity for translational science. Clinical Pharmacology and Therapeutics. 94: 291-6. PMID 23963214 DOI: 10.1038/clpt.2013.84  1
2013 Song WL, FitzGerald GA. Niacin, an old drug with a new twist. Journal of Lipid Research. 54: 2586-94. PMID 23948546 DOI: 10.1194/jlr.R040592  1
2013 Bhala N, Emberson J, Merhi A, Abramson S, Arber N, Baron JA, Bombardier C, Cannon C, Farkouh ME, FitzGerald GA, Goss P, Halls H, Hawk E, Hawkey C, et al. Vascular and upper gastrointestinal effects of non-steroidal anti-inflammatory drugs: meta-analyses of individual participant data from randomised trials. Lancet. 382: 769-79. PMID 23726390 DOI: 10.1016/S0140-6736(13)60900-9  1
2013 Toki S, Goleniewska K, Huckabee MM, Zhou W, Newcomb DC, Fitzgerald GA, Lawson WE, Peebles RS. PGIâ‚‚ signaling inhibits antigen uptake and increases migration of immature dendritic cells. Journal of Leukocyte Biology. 94: 77-88. PMID 23625201 DOI: 10.1189/jlb.1112559  1
2013 Curtis AM, FitzGerald GA. Platelet microRNAs: Novy Mir* or mired in human complexity? Circulation Research. 112: 576-8. PMID 23410874 DOI: 10.1161/CIRCRESAHA.113.300859  0.6
2013 Ricciotti E, Yu Y, Grosser T, Fitzgerald GA. COX-2, the dominant source of prostacyclin. Proceedings of the National Academy of Sciences of the United States of America. 110: E183. PMID 23292931 DOI: 10.1073/pnas.1219073110  1
2013 Fitzgerald DJ, Fitzgerald GA. Historical lessons in translational medicine: cyclooxygenase inhibition and P2Y12 antagonism. Circulation Research. 112: 174-94. PMID 23287454 DOI: 10.1161/CIRCRESAHA.111.300271  1
2013 Yu Z, Ricciotti E, Miwa T, Liu S, Ihida-Stansbury K, Landersberg G, Jones PL, Scalia R, Song WC, Assoian RK, FitzGerald GA. Myeloid cell 5-lipoxygenase activating protein modulates the response to vascular injury. Circulation Research. 112: 432-40. PMID 23250985 DOI: 10.1161/CIRCRESAHA.112.300755  1
2013 Grosser T, Fries S, Lawson JA, Kapoor SC, Grant GR, FitzGerald GA. Drug resistance and pseudoresistance: an unintended consequence of enteric coating aspirin. Circulation. 127: 377-85. PMID 23212718 DOI: 10.1161/CIRCULATIONAHA.112.117283  1
2013 Chen L, Yang G, Xu X, Grant G, Lawson JA, Bohlooly-Y M, FitzGerald GA. Cell selective cardiovascular biology of microsomal prostaglandin E synthase-1. Circulation. 127: 233-43. PMID 23204105 DOI: 10.1161/CIRCULATIONAHA.112.119479  0.44
2013 Nelson AM, Loy DE, Lawson JA, Katseff AS, Fitzgerald GA, Garza LA. Prostaglandin D2 inhibits wound-induced hair follicle neogenesis through the receptor, Gpr44. The Journal of Investigative Dermatology. 133: 881-9. PMID 23190891 DOI: 10.1038/jid.2012.398  0.44
2013 Funk CD, Song WC, FitzGerald GA. Prostaglandins and Other Lipid Mediators in Reproductive Medicine Yen and Jaffe's Reproductive Endocrinology: Seventh Edition. 108-123. DOI: 10.1016/B978-1-4557-2758-2.00006-8  1
2013 Hirankarn S, Barrett JS, Alamuddin N, Fitzgerald GA, Skarke C. GCG100649, a novel cyclooxygenase-2 inhibitor, exhibits a drug disposition profile in healthy volunteers compatible with high affinity to carbonic anhydrase-i/ii: Preliminary dose-exposure relationships to define clinical development strategies Clinical Pharmacology in Drug Development. 2: 379-386. DOI: 10.1002/cpdd.47  1
2012 Paschos GK, Ibrahim S, Song WL, Kunieda T, Grant G, Reyes TM, Bradfield CA, Vaughan CH, Eiden M, Masoodi M, Griffin JL, Wang F, Lawson JA, Fitzgerald GA. Obesity in mice with adipocyte-specific deletion of clock component Arntl. Nature Medicine. 18: 1768-77. PMID 23142819 DOI: 10.1038/nm.2979  0.72
2012 Lowell AN, Qiao H, Liu T, Ishikawa T, Zhang H, Oriana S, Wang M, Ricciotti E, FitzGerald GA, Zhou R, Yamakoshi Y. Functionalized low-density lipoprotein nanoparticles for in vivo enhancement of atherosclerosis on magnetic resonance images. Bioconjugate Chemistry. 23: 2313-9. PMID 23075169 DOI: 10.1021/bc300561e  0.52
2012 Olson MT, Kickler TS, Lawson JA, McLean RC, Jani J, FitzGerald GA, Rade JJ. Effect of assay specificity on the association of urine 11-dehydro thromboxane B2 determination with cardiovascular risk. Journal of Thrombosis and Haemostasis : Jth. 10: 2462-9. PMID 23072449 DOI: 10.1111/jth.12026  0.44
2012 Zhou W, Dowell DR, Huckabee MM, Newcomb DC, Boswell MG, Goleniewska K, Lotz MT, Toki S, Yin H, Yao S, Natarajan C, Wu P, Sriram S, Breyer RM, Fitzgerald GA, et al. Prostaglandin I2 signaling drives Th17 differentiation and exacerbates experimental autoimmune encephalomyelitis. Plos One. 7: e33518. PMID 22590492 DOI: 10.1371/journal.pone.0033518  1
2012 Yu Y, Ricciotti E, Scalia R, Tang SY, Grant G, Yu Z, Landesberg G, Crichton I, Wu W, Puré E, Funk CD, FitzGerald GA. Vascular COX-2 modulates blood pressure and thrombosis in mice. Science Translational Medicine. 4: 132ra54. PMID 22553252 DOI: 10.1126/scitranslmed.3003787  1
2012 Yu Z, Crichton I, Tang SY, Hui Y, Ricciotti E, Levin MD, Lawson JA, Puré E, FitzGerald GA. Disruption of the 5-lipoxygenase pathway attenuates atherogenesis consequent to COX-2 deletion in mice. Proceedings of the National Academy of Sciences of the United States of America. 109: 6727-32. PMID 22493243 DOI: 10.1073/pnas.1115313109  1
2012 Garza LA, Liu Y, Yang Z, Alagesan B, Lawson JA, Norberg SM, Loy DE, Zhao T, Blatt HB, Stanton DC, Carrasco L, Ahluwalia G, Fischer SM, FitzGerald GA, Cotsarelis G. Prostaglandin D2 inhibits hair growth and is elevated in bald scalp of men with androgenetic alopecia. Science Translational Medicine. 4: 126ra34. PMID 22440736 DOI: 10.1126/scitranslmed.3003122  1
2012 Song WL, Stubbe J, Ricciotti E, Alamuddin N, Ibrahim S, Crichton I, Prempeh M, Lawson JA, Wilensky RL, Rasmussen LM, Puré E, FitzGerald GA. Niacin and biosynthesis of PGDâ‚‚by platelet COX-1 in mice and humans. The Journal of Clinical Investigation. 122: 1459-68. PMID 22406532 DOI: 10.1172/JCI59262  1
2012 Bubela T, FitzGerald GA, Gold ER. Recalibrating intellectual property rights to enhance translational research collaborations. Science Translational Medicine. 4: 122cm3. PMID 22357536 DOI: 10.1126/scitranslmed.3003490  1
2012 Saxena R, Elbers CC, Guo Y, Peter I, Gaunt TR, Mega JL, Lanktree MB, Tare A, Castillo BA, Li YR, Johnson T, Bruinenberg M, Gilbert-Diamond D, Rajagopalan R, Voight BF, ... ... FitzGerald GA, et al. Large-scale gene-centric meta-analysis across 39 studies identifies type 2 diabetes loci. American Journal of Human Genetics. 90: 410-25. PMID 22325160 DOI: 10.1016/j.ajhg.2011.12.022  0.56
2012 Skarke C, Alamuddin N, Lawson JA, Cen L, Propert KJ, Fitzgerald GA. Comparative impact on prostanoid biosynthesis of celecoxib and the novel nonsteroidal anti-inflammatory drug CG100649. Clinical Pharmacology and Therapeutics. 91: 986-93. PMID 22278334 DOI: 10.1038/clpt.2012.3  1
2012 Dovizio M, Tacconelli S, Ricciotti E, Bruno A, Maier TJ, Anzellotti P, Di Francesco L, Sala P, Signoroni S, Bertario L, Dixon DA, Lawson JA, Steinhilber D, FitzGerald GA, Patrignani P. Effects of celecoxib on prostanoid biosynthesis and circulating angiogenesis proteins in familial adenomatous polyposis. The Journal of Pharmacology and Experimental Therapeutics. 341: 242-50. PMID 22262921 DOI: 10.1124/jpet.111.190785  1
2011 Meagher EA, Fitzgerald GA. Efficient drug approval and monitoring must rely on sound regulatory science. Nature Medicine. 17: 1535. PMID 22146443 DOI: 10.1038/nm1211-1535  1
2011 FitzGerald GA. Re-engineering drug discovery and development. Ldi Issue Brief. 17: 1-4. PMID 22049582  1
2011 Serrano GE, Lelutiu N, Rojas A, Cochi S, Shaw R, Makinson CD, Wang D, FitzGerald GA, Dingledine R. Ablation of cyclooxygenase-2 in forebrain neurons is neuroprotective and dampens brain inflammation after status epilepticus. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 14850-60. PMID 22016518 DOI: 10.1523/JNEUROSCI.3922-11.2011  1
2011 Edelman ER, FitzGerald GA. A rattle bag of science and the art of translation. Science Translational Medicine. 3: 104ed3. PMID 21998406 DOI: 10.1126/scitranslmed.3002131  1
2011 Jaffar Z, Ferrini ME, Shaw PK, FitzGerald GA, Roberts K. Prostaglandin Iâ‚‚promotes the development of IL-17-producing γδ T cells that associate with the epithelium during allergic lung inflammation. Journal of Immunology (Baltimore, Md. : 1950). 187: 5380-91. PMID 21976777 DOI: 10.4049/jimmunol.1101261  1
2011 Markosyan N, Chen EP, Ndong VN, Yao Y, Sterner CJ, Chodosh LA, Lawson JA, Fitzgerald GA, Smyth EM. Deletion of cyclooxygenase 2 in mouse mammary epithelial cells delays breast cancer onset through augmentation of type 1 immune responses in tumors. Carcinogenesis. 32: 1441-9. PMID 21771729 DOI: 10.1093/carcin/bgr134  1
2011 FitzGerald GA. NCATS purrs: emerging signs of form and function. Science Translational Medicine. 3: 83ed2. PMID 21593398 DOI: 10.1126/scitranslmed.3002232  1
2011 Ricciotti E, FitzGerald GA. Prostaglandins and inflammation. Arteriosclerosis, Thrombosis, and Vascular Biology. 31: 986-1000. PMID 21508345 DOI: 10.1161/ATVBAHA.110.207449  1
2011 Winnik S, Lohmann C, Richter EK, Schäfer N, Song WL, Leiber F, Mocharla P, Hofmann J, Klingenberg R, Borén J, Becher B, Fitzgerald GA, Lüscher TF, Matter CM, Beer JH. Dietary α-linolenic acid diminishes experimental atherogenesis and restricts T cell-driven inflammation. European Heart Journal. 32: 2573-84. PMID 21285075 DOI: 10.1093/eurheartj/ehq501  1
2011 Wang M, Ihida-Stansbury K, Kothapalli D, Tamby MC, Yu Z, Chen L, Grant G, Cheng Y, Lawson JA, Assoian RK, Jones PL, Fitzgerald GA. Microsomal prostaglandin e2 synthase-1 modulates the response to vascular injury. Circulation. 123: 631-9. PMID 21282500 DOI: 10.1161/CIRCULATIONAHA.110.973685  1
2011 FitzGerald GA. Regulatory science: what it is and why we need it. Clinical Pharmacology and Therapeutics. 89: 291-4. PMID 21160470 DOI: 10.1038/clpt.2010.276  1
2011 Daham K, Song WL, Lawson JA, Kupczyk M, Gülich A, Dahlén SE, FitzGerald GA, Dahlén B. Effects of celecoxib on major prostaglandins in asthma. Clinical and Experimental Allergy : Journal of the British Society For Allergy and Clinical Immunology. 41: 36-45. PMID 20880055 DOI: 10.1111/j.1365-2222.2010.03617.x  1
2010 Wang M, FitzGerald GA. Cardiovascular biology of microsomal prostaglandin E synthase-1. Trends in Cardiovascular Medicine. 20: 189-95. PMID 22137640 DOI: 10.1016/j.tcm.2011.04.002  1
2010 Fitzgerald G. Drug development needs a new brand of science Nature. 468: 869. PMID 21164436 DOI: 10.1038/468869a  1
2010 Piano MR, Benowitz NL, Fitzgerald GA, Corbridge S, Heath J, Hahn E, Pechacek TF, Howard G. Impact of smokeless tobacco products on cardiovascular disease: implications for policy, prevention, and treatment: a policy statement from the American Heart Association. Circulation. 122: 1520-44. PMID 20837898 DOI: 10.1161/CIR.0b013e3181f432c3  1
2010 FitzGerald GA. Perestroika in pharma: evolution or revolution in drug development? The Mount Sinai Journal of Medicine, New York. 77: 327-32. PMID 20687177 DOI: 10.1002/msj.20198  1
2010 Hui Y, Ricciotti E, Crichton I, Yu Z, Wang D, Stubbe J, Wang M, Puré E, FitzGerald GA. Targeted deletions of cyclooxygenase-2 and atherogenesis in mice. Circulation. 121: 2654-60. PMID 20530000 DOI: 10.1161/CIRCULATIONAHA.109.910687  1
2010 Skarke C, FitzGerald GA. Training translators for smart drug discovery. Science Translational Medicine. 2: 26cm12. PMID 20375362 DOI: 10.1126/scitranslmed.3000890  1
2010 Wang M, Cooper PR, Jiang M, Zhao H, Hui Y, Yao Y, Tate JC, Damera G, Lawson JA, Jester WF, Haczku A, Panettieri RA, FitzGerald GA. Deletion of microsomal prostaglandin E synthase-1 does not alter ozone-induced airway hyper-responsiveness. The Journal of Pharmacology and Experimental Therapeutics. 334: 63-8. PMID 20371706 DOI: 10.1124/jpet.110.166678  1
2010 Paschos GK, FitzGerald GA. Circadian clocks and vascular function. Circulation Research. 106: 833-41. PMID 20299673 DOI: 10.1161/CIRCRESAHA.109.211706  1
2010 Reis SE, Berglund L, Bernard GR, Califf RM, Fitzgerald GA, Johnson PC. Reengineering the national clinical and translational research enterprise: the strategic plan of the National Clinical and Translational Science Awards Consortium. Academic Medicine : Journal of the Association of American Medical Colleges. 85: 463-9. PMID 20182119 DOI: 10.1097/ACM.0b013e3181ccc877  1
2010 Grosser T, Yu Y, Fitzgerald GA. Emotion recollected in tranquility: lessons learned from the COX-2 saga. Annual Review of Medicine. 61: 17-33. PMID 20059330 DOI: 10.1146/annurev-med-011209-153129  1
2010 Paschos GK, Baggs JE, Hogenesch JB, FitzGerald GA. The role of clock genes in pharmacology. Annual Review of Pharmacology and Toxicology. 50: 187-214. PMID 20055702 DOI: 10.1146/annurev.pharmtox.010909.105621  1
2010 Yu Y, Stubbe J, Ibrahim S, Song WL, Smyth EM, Symth EM, Funk CD, FitzGerald GA. Cyclooxygenase-2-dependent prostacyclin formation and blood pressure homeostasis: targeted exchange of cyclooxygenase isoforms in mice. Circulation Research. 106: 337-45. PMID 19940265 DOI: 10.1161/CIRCRESAHA.109.204529  1
2010 Smyth EM, FitzGerald GA. Prostaglandin mediators Handbook of Cell Signaling, 2/E. 2: 1219-1228. DOI: 10.1016/B978-0-12-374145-5.00150-9  1
2010 Paschos GK, FitzGerald GA. Biological clocks: A cardiovascular perspective Dialogues in Cardiovascular Medicine. 15: 7-24.  1
2009 Chang CT, Patel P, Gore V, Song WL, Lawson JA, Powell WS, Fitzgerald GA, Rokach J. A new approach to the synthesis of polyunsaturated deuterated isoprostanes: total synthesis of d4-5-epi-8,12-iso-iPF3alpha-VI and d4-8,12-iso-iPF3alpha-VI. Bioorganic & Medicinal Chemistry Letters. 19: 6755-8. PMID 19846297 DOI: 10.1016/j.bmcl.2009.09.099  1
2009 Maree AO, Fitzgerald GA. A roadmap for the twilight zone: navigating United States cardiovascular career development for international trainees. Circulation. 120: 1542-9. PMID 19822817 DOI: 10.1161/CIRCULATIONAHA.108.811646  1
2009 Greenbaum DC, FitzGerald GA. Platelets, pyrexia, and plasmodia. The New England Journal of Medicine. 361: 526-8. PMID 19641212 DOI: 10.1056/NEJMcibr0903050  1
2009 Yu Y, Ricciotti E, Grosser T, Fitzgerald GA. The translational therapeutics of prostaglandin inhibition in atherothrombosis. Journal of Thrombosis and Haemostasis : Jth. 7: 222-6. PMID 19630805 DOI: 10.1111/j.1538-7836.2009.03439.x  1
2009 Grad E, Golomb M, Koroukhov N, Lawson JA, Lotan C, Fitzgerald GA, Danenberg HD. Aspirin reduces the prothrombotic activity of C-reactive protein. Journal of Thrombosis and Haemostasis : Jth. 7: 1393-400. PMID 19522741 DOI: 10.1111/j.1538-7836.2009.03511.x  1
2009 Song WL, Paschos G, Fries S, Reilly MP, Yu Y, Rokach J, Chang CT, Patel P, Lawson JA, Fitzgerald GA. Novel eicosapentaenoic acid-derived F3-isoprostanes as biomarkers of lipid peroxidation. The Journal of Biological Chemistry. 284: 23636-43. PMID 19520854 DOI: 10.1074/jbc.M109.024075  1
2009 Yu Y, Lucitt MB, Stubbe J, Cheng Y, Friis UG, Hansen PB, Jensen BL, Smyth EM, FitzGerald GA. Prostaglandin F2alpha elevates blood pressure and promotes atherosclerosis. Proceedings of the National Academy of Sciences of the United States of America. 106: 7985-90. PMID 19416858 DOI: 10.1073/pnas.0811834106  1
2009 Wang D, Patel VV, Ricciotti E, Zhou R, Levin MD, Gao E, Yu Z, Ferrari VA, Lu MM, Xu J, Zhang H, Hui Y, Cheng Y, Petrenko N, Yu Y, ... FitzGerald GA, et al. Cardiomyocyte cyclooxygenase-2 influences cardiac rhythm and function. Proceedings of the National Academy of Sciences of the United States of America. 106: 7548-52. PMID 19376970 DOI: 10.1073/pnas.0805806106  1
2009 Baggs JE, Price TS, DiTacchio L, Panda S, Fitzgerald GA, Hogenesch JB. Network features of the mammalian circadian clock. Plos Biology. 7: e52. PMID 19278294 DOI: 10.1371/journal.pbio.1000052  1
2009 Vardeh D, Wang D, Costigan M, Lazarus M, Saper CB, Woolf CJ, Fitzgerald GA, Samad TA. COX2 in CNS neural cells mediates mechanical inflammatory pain hypersensitivity in mice. The Journal of Clinical Investigation. 119: 287-94. PMID 19127021 DOI: 10.1172/JCI37098  1
2009 Smyth EM, Grosser T, Wang M, Yu Y, FitzGerald GA. Prostanoids in health and disease. Journal of Lipid Research. 50: S423-8. PMID 19095631 DOI: 10.1194/jlr.R800094-JLR200  1
2009 FitzGerald GA. Moving clinical research in academic medical centres up the value chain Nature Reviews Drug Discovery. 8: 597. DOI: 10.1038/nrd2954  1
2009 FitzGerald GA. Foreword Clinical and Translational Science. xiii. DOI: 10.1016/B978-0-12-373639-0.00001-7  1
2008 Keating BJ, Tischfield S, Murray SS, Bhangale T, Price TS, Glessner JT, Galver L, Barrett JC, Grant SF, Farlow DN, Chandrupatla HR, Hansen M, Ajmal S, Papanicolaou GJ, Guo Y, ... ... Fitzgerald GA, et al. Concept, design and implementation of a cardiovascular gene-centric 50 k SNP array for large-scale genomic association studies. Plos One. 3: e3583. PMID 18974833 DOI: 10.1371/journal.pone.0003583  1
2008 Price TS, Baggs JE, Curtis AM, Fitzgerald GA, Hogenesch JB. WAVECLOCK: wavelet analysis of circadian oscillation. Bioinformatics (Oxford, England). 24: 2794-5. PMID 18931366 DOI: 10.1093/bioinformatics/btn521  1
2008 Parastatidis I, Thomson L, Burke A, Chernysh I, Nagaswami C, Visser J, Stamer S, Liebler DC, Koliakos G, Heijnen HF, Fitzgerald GA, Weisel JW, Ischiropoulos H. Fibrinogen beta-chain tyrosine nitration is a prothrombotic risk factor. The Journal of Biological Chemistry. 283: 33846-53. PMID 18818200 DOI: 10.1074/jbc.M805522200  1
2008 Chang CT, Patel P, Kang N, Lawson JA, Song WL, Powell WS, FitzGerald GA, Rokach J. Eicosapentaenoic-acid-derived isoprostanes: synthesis and discovery of two major isoprostanes. Bioorganic & Medicinal Chemistry Letters. 18: 5523-7. PMID 18804370 DOI: 10.1016/j.bmcl.2008.09.008  1
2008 FitzGerald GA. Guest authorship, mortality reporting, and integrity in rofecoxib studies. Jama. 300: 900-1; author reply . PMID 18728254 DOI: 10.1001/jama.300.8.900-b  1
2008 Fitzgerald GA. Drugs, industry, and academia. Science (New York, N.Y.). 320: 1563. PMID 18566251 DOI: 10.1126/science.1161006  1
2008 Chen M, Boilard E, Nigrovic PA, Clark P, Xu D, Fitzgerald GA, Audoly LP, Lee DM. Predominance of cyclooxygenase 1 over cyclooxygenase 2 in the generation of proinflammatory prostaglandins in autoantibody-driven K/BxN serum-transfer arthritis. Arthritis and Rheumatism. 58: 1354-65. PMID 18438856 DOI: 10.1002/art.23453  1
2008 Ky B, Burke A, Tsimikas S, Wolfe ML, Tadesse MG, Szapary PO, Witztum JL, FitzGerald GA, Rader DJ. The influence of pravastatin and atorvastatin on markers of oxidative stress in hypercholesterolemic humans. Journal of the American College of Cardiology. 51: 1653-62. PMID 18436117 DOI: 10.1016/j.jacc.2008.01.026  1
2008 Westgate EJ, Cheng Y, Reilly DF, Price TS, Walisser JA, Bradfield CA, FitzGerald GA. Genetic components of the circadian clock regulate thrombogenesis in vivo. Circulation. 117: 2087-95. PMID 18413500 DOI: 10.1161/CIRCULATIONAHA.107.739227  1
2008 Wang M, Song WL, Cheng Y, Fitzgerald GA. Microsomal prostaglandin E synthase-1 inhibition in cardiovascular inflammatory disease. Journal of Internal Medicine. 263: 500-5. PMID 18410593 DOI: 10.1111/j.1365-2796.2008.01938.x  1
2008 FitzGerald GA. Translational therapeutics at the platelet vascular interface. Summary. Arteriosclerosis, Thrombosis, and Vascular Biology. 28: s51-2. PMID 18296588 DOI: 10.1161/ATVBAHA.108.162206  1
2008 FitzGerald GA. Translational therapeutics at the platelet vascular interface. Introduction. Arteriosclerosis, Thrombosis, and Vascular Biology. 28: s3-4. PMID 18296587 DOI: 10.1161/ATVBAHA.108.162198  1
2008 Wang M, Lee E, Song W, Ricciotti E, Rader DJ, Lawson JA, Puré E, FitzGerald GA. Microsomal prostaglandin E synthase-1 deletion suppresses oxidative stress and angiotensin II-induced abdominal aortic aneurysm formation. Circulation. 117: 1302-9. PMID 18285567 DOI: 10.1161/CIRCULATIONAHA.107.731398  1
2008 Kunieda T, Minamino T, Miura K, Katsuno T, Tateno K, Miyauchi H, Kaneko S, Bradfield CA, FitzGerald GA, Komuro I. Reduced nitric oxide causes age-associated impairment of circadian rhythmicity. Circulation Research. 102: 607-14. PMID 18218984 DOI: 10.1161/CIRCRESAHA.107.162230  1
2008 Lucitt MB, Price TS, Pizarro A, Wu W, Yocum AK, Seiler C, Pack MA, Blair IA, Fitzgerald GA, Grosser T. Analysis of the zebrafish proteome during embryonic development. Molecular & Cellular Proteomics : McP. 7: 981-94. PMID 18212345 DOI: 10.1074/mcp.M700382-MCP200  1
2008 Song WL, Wang M, Ricciotti E, Fries S, Yu Y, Grosser T, Reilly M, Lawson JA, FitzGerald GA. Tetranor PGDM, an abundant urinary metabolite reflects biosynthesis of prostaglandin D2 in mice and humans. The Journal of Biological Chemistry. 283: 1179-88. PMID 17993463 DOI: 10.1074/jbc.M706839200  1
2008 Reilly DF, Curtis AM, Cheng Y, Westgate EJ, Rudic RD, Paschos G, Morris J, Ouyang M, Thomas SA, FitzGerald GA. Peripheral circadian clock rhythmicity is retained in the absence of adrenergic signaling. Arteriosclerosis, Thrombosis, and Vascular Biology. 28: 121-6. PMID 17975121 DOI: 10.1161/ATVBAHA.107.152538  1
2008 Song WL, Lawson JA, Reilly D, Rokach J, Chang CT, Giasson B, FitzGerald GA. Neurofurans, novel indices of oxidant stress derived from docosahexaenoic acid. The Journal of Biological Chemistry. 283: 6-16. PMID 17921521 DOI: 10.1074/jbc.M706124200  1
2007 Funk CD, FitzGerald GA. COX-2 inhibitors and cardiovascular risk. Journal of Cardiovascular Pharmacology. 50: 470-9. PMID 18030055 DOI: 10.1097/FJC.0b013e318157f72d  1
2007 Song WL, Lawson JA, Wang M, Zou H, FitzGerald GA. Noninvasive assessment of the role of cyclooxygenases in cardiovascular health: a detailed HPLC/MS/MS method. Methods in Enzymology. 433: 51-72. PMID 17954228 DOI: 10.1016/S0076-6879(07)33003-6  1
2007 Jaffar Z, Ferrini ME, Buford MC, Fitzgerald GA, Roberts K. Prostaglandin I2-IP signaling blocks allergic pulmonary inflammation by preventing recruitment of CD4+ Th2 cells into the airways in a mouse model of asthma. Journal of Immunology (Baltimore, Md. : 1950). 179: 6193-203. PMID 17947695  1
2007 Huang JC, Wun WS, Goldsby JS, Egan K, FitzGerald GA, Wu KK. Prostacyclin receptor signaling and early embryo development in the mouse. Human Reproduction (Oxford, England). 22: 2851-6. PMID 17905746 DOI: 10.1093/humrep/dem304  1
2007 North TE, Goessling W, Walkley CR, Lengerke C, Kopani KR, Lord AM, Weber GJ, Bowman TV, Jang IH, Grosser T, Fitzgerald GA, Daley GQ, Orkin SH, Zon LI. Prostaglandin E2 regulates vertebrate haematopoietic stem cell homeostasis. Nature. 447: 1007-11. PMID 17581586 DOI: 10.1038/nature05883  1
2007 FitzGerald GA. COX-2 in play at the AHA and the FDA. Trends in Pharmacological Sciences. 28: 303-7. PMID 17573128 DOI: 10.1016/  1
2007 Reilly DF, Westgate EJ, FitzGerald GA. Peripheral circadian clocks in the vasculature. Arteriosclerosis, Thrombosis, and Vascular Biology. 27: 1694-705. PMID 17541024 DOI: 10.1161/ATVBAHA.107.144923  1
2007 Wada M, DeLong CJ, Hong YH, Rieke CJ, Song I, Sidhu RS, Yuan C, Warnock M, Schmaier AH, Yokoyama C, Smyth EM, Wilson SJ, FitzGerald GA, Garavito RM, Sui de X, et al. Enzymes and receptors of prostaglandin pathways with arachidonic acid-derived versus eicosapentaenoic acid-derived substrates and products. The Journal of Biological Chemistry. 282: 22254-66. PMID 17519235 DOI: 10.1074/jbc.M703169200  1
2007 García Rodríguez LA, Egan K, FitzGerald GA. Traditional nonsteroidal anti-inflammatory drugs and postmenopausal hormone therapy: a drug-drug interaction? Plos Medicine. 4: e157. PMID 17518513 DOI: 10.1371/journal.pmed.0040157  1
2007 Chou WL, Chuang LM, Chou CC, Wang AH, Lawson JA, FitzGerald GA, Chang ZF. Identification of a novel prostaglandin reductase reveals the involvement of prostaglandin E2 catabolism in regulation of peroxisome proliferator-activated receptor gamma activation. The Journal of Biological Chemistry. 282: 18162-72. PMID 17449869 DOI: 10.1074/jbc.M702289200  1
2007 Curtis AM, Cheng Y, Kapoor S, Reilly D, Price TS, Fitzgerald GA. Circadian variation of blood pressure and the vascular response to asynchronous stress. Proceedings of the National Academy of Sciences of the United States of America. 104: 3450-5. PMID 17360665 DOI: 10.1073/pnas.0611680104  1
2007 Zhou W, Hashimoto K, Goleniewska K, O'Neal JF, Ji S, Blackwell TS, Fitzgerald GA, Egan KM, Geraci MW, Peebles RS. Prostaglandin I2 analogs inhibit proinflammatory cytokine production and T cell stimulatory function of dendritic cells. Journal of Immunology (Baltimore, Md. : 1950). 178: 702-10. PMID 17202330 DOI: 10.4049/JIMMUNOL.178.2.702  1
2007 Fitzgerald GA. Clinical pharmacology or translational medicine and therapeutics: reinvent or rebrand and expand? Clinical Pharmacology and Therapeutics. 81: 19-20. PMID 17185991 DOI: 10.1038/sj.clpt.6100044  1
2007 Price TS, Lucitt MB, Wu W, Austin DJ, Pizarro A, Yocum AK, Blair IA, FitzGerald GA, Grosser T. EBP, a program for protein identification using multiple tandem mass spectrometry datasets. Molecular & Cellular Proteomics : McP. 6: 527-36. PMID 17164401 DOI: 10.1074/mcp.T600049-MCP200  1
2007 Zhou W, Blackwell TS, Goleniewska K, O'Neal JF, Fitzgerald GA, Lucitt M, Breyer RM, Peebles RS. Prostaglandin I2 analogs inhibit Th1 and Th2 effector cytokine production by CD4 T cells. Journal of Leukocyte Biology. 81: 809-17. PMID 17135575 DOI: 10.1189/jlb.0606375  1
2007 Yu Y, Fan J, Hui Y, Rouzer CA, Marnett LJ, Klein-Szanto AJ, FitzGerald GA, Funk CD. Targeted cyclooxygenase gene (ptgs) exchange reveals discriminant isoform functionality. The Journal of Biological Chemistry. 282: 1498-506. PMID 17110378 DOI: 10.1074/jbc.M609930200  1
2006 Curtis AM, Fitzgerald GA. Central and peripheral clocks in cardiovascular and metabolic function. Annals of Medicine. 38: 552-9. PMID 17438670 DOI: 10.1080/07853890600995010  1
2006 Cannon CP, Curtis SP, FitzGerald GA, Krum H, Kaur A, Bolognese JA, Reicin AS, Bombardier C, Weinblatt ME, van der Heijde D, Erdmann E, Laine L. Cardiovascular outcomes with etoricoxib and diclofenac in patients with osteoarthritis and rheumatoid arthritis in the Multinational Etoricoxib and Diclofenac Arthritis Long-term (MEDAL) programme: a randomised comparison. Lancet. 368: 1771-81. PMID 17113426 DOI: 10.1016/S0140-6736(06)69666-9  1
2006 Egan K, FitzGerald GA. Eicosanoids and the vascular endothelium. Handbook of Experimental Pharmacology. 189-211. PMID 16999220 DOI: 10.1007/3-540-32967-6-6  1
2006 Wang M, Zukas AM, Hui Y, Ricciotti E, Puré E, FitzGerald GA. Deletion of microsomal prostaglandin E synthase-1 augments prostacyclin and retards atherogenesis. Proceedings of the National Academy of Sciences of the United States of America. 103: 14507-12. PMID 16973753 DOI: 10.1073/pnas.0606586103  1
2006 Lawson JA, Kim S, Powell WS, FitzGerald GA, Rokach J. Oxidized derivatives of omega-3 fatty acids: identification of IPF3 alpha-VI in human urine. Journal of Lipid Research. 47: 2515-24. PMID 16943517 DOI: 10.1194/jlr.M600327-JLR200  1
2006 Yu Y, Fan J, Chen XS, Wang D, Klein-Szanto AJ, Campbell RL, FitzGerald GA, Funk CD. Genetic model of selective COX2 inhibition reveals novel heterodimer signaling. Nature Medicine. 12: 699-704. PMID 16732282 DOI: 10.1038/nm1412  1
2006 Crofford LJ, Breyer MD, Strand CV, Rushitzka F, Brune K, Farkouh ME, Simon LS, FitzGerald GA, Patrono C. Cardiovascular effects of selective COX-2 inhibition: Is there a class effect? The international COX-2 study group Journal of Rheumatology. 33: 1403-1408. PMID 16724374  1
2006 Cheng Y, Wang M, Yu Y, Lawson J, Funk CD, Fitzgerald GA. Cyclooxygenases, microsomal prostaglandin E synthase-1, and cardiovascular function. The Journal of Clinical Investigation. 116: 1391-9. PMID 16614756 DOI: 10.1172/JCI27540  1
2006 Lovgren AK, Jania LA, Hartney JM, Parsons KK, Audoly LP, Fitzgerald GA, Tilley SL, Koller BH. COX-2-derived prostacyclin protects against bleomycin-induced pulmonary fibrosis. American Journal of Physiology. Lung Cellular and Molecular Physiology. 291: L144-56. PMID 16473862 DOI: 10.1152/ajplung.00492.2005  1
2006 Jacobo SH, Chang CT, Lee GJ, Lawson JA, Powell WS, Pratico D, FitzGerald GA, Rokach J. Total synthesis of 8,12-iso-iPF3alpha-VI, an EPA-derived isoprostane: stereoselective introduction of the fifth asymmetric center. The Journal of Organic Chemistry. 71: 1370-9. PMID 16468784 DOI: 10.1021/jo051916x  1
2006 Fries S, Grosser T, Price TS, Lawson JA, Kapoor S, DeMarco S, Pletcher MT, Wiltshire T, FitzGerald GA. Marked interindividual variability in the response to selective inhibitors of cyclooxygenase-2. Gastroenterology. 130: 55-64. PMID 16401468 DOI: 10.1053/j.gastro.2005.10.002  1
2006 Grosser T, Fries S, FitzGerald GA. Biological basis for the cardiovascular consequences of COX-2 inhibition: therapeutic challenges and opportunities. The Journal of Clinical Investigation. 116: 4-15. PMID 16395396 DOI: 10.1172/JCI27291  1
2006 Woon PY, Curtis AM, Kaisaki PJ, Argoud K, Wallace KJ, Bihoreau MT, FitzGerald GA, Gauguier D. Genomic organization of the rat Clock gene and sequence analysis in inbred rat strains. Genomics. 87: 208-17. PMID 16376516 DOI: 10.1016/j.ygeno.2005.10.006  1
2006 Ali FY, Egan K, FitzGerald GA, Desvergne B, Wahli W, Bishop-Bailey D, Warner TD, Mitchell JA. Role of prostacyclin versus peroxisome proliferator-activated receptor beta receptors in prostacyclin sensing by lung fibroblasts. American Journal of Respiratory Cell and Molecular Biology. 34: 242-6. PMID 16239641 DOI: 10.1165/rcmb.2005-0289OC  1
2005 Rudic RD, McNamara P, Reilly D, Grosser T, Curtis AM, Price TS, Panda S, Hogenesch JB, FitzGerald GA. Bioinformatic analysis of circadian gene oscillation in mouse aorta. Circulation. 112: 2716-24. PMID 16230482 DOI: 10.1161/CIRCULATIONAHA.105.568626  1
2005 Francois H, Athirakul K, Howell D, Dash R, Mao L, Kim HS, Rockman HA, Fitzgerald GA, Koller BH, Coffman TM. Prostacyclin protects against elevated blood pressure and cardiac fibrosis. Cell Metabolism. 2: 201-7. PMID 16154102 DOI: 10.1016/j.cmet.2005.08.005  1
2005 Westgate EJ, Fitzgerald GA. Pulmonary embolism in a woman taking oral contraceptives and valdecoxib. Plos Medicine. 2: e197. PMID 16013893 DOI: 10.1371/journal.pmed.0020197  1
2005 Rudic RD, Brinster D, Cheng Y, Fries S, Song WL, Austin S, Coffman TM, FitzGerald GA. COX-2-derived prostacyclin modulates vascular remodeling. Circulation Research. 96: 1240-7. PMID 15905461 DOI: 10.1161/01.RES.0000170888.11669.28  1
2005 Rudic RD, Curtis AM, Cheng Y, FitzGerald G. Peripheral clocks and the regulation of cardiovascular and metabolic function Methods in Enzymology. 393: 524-539. PMID 15817310 DOI: 10.1016/S0076-6879(05)93027-9  1
2005 Wang D, Wong D, Wang M, Cheng Y, Fitzgerald GA. Cardiovascular hazard and non-steroidal anti-inflammatory drugs. Current Opinion in Pharmacology. 5: 204-10. PMID 15780832 DOI: 10.1016/j.coph.2005.02.001  1
2005 Yu Y, Cheng Y, Fan J, Chen XS, Klein-Szanto A, Fitzgerald GA, Funk CD. Differential impact of prostaglandin H synthase 1 knockdown on platelets and parturition. The Journal of Clinical Investigation. 115: 986-95. PMID 15776109 DOI: 10.1172/JCI23683  1
2005 Kim S, Powell WS, Lawson JA, Jacobo SH, Pratico D, FitzGerald GA, Maxey K, Rokach J. iPF2alpha-III-17,18,19,20-d4: total synthesis and metabolism. Bioorganic & Medicinal Chemistry Letters. 15: 1613-7. PMID 15745808 DOI: 10.1016/j.bmcl.2005.01.062  1
2005 Kadiiska MB, Gladen BC, Baird DD, Graham LB, Parker CE, Ames BN, Basu S, Fitzgerald GA, Lawson JA, Marnett LJ, Morrow JD, Murray DM, Plastaras J, Roberts LJ, Rokach J, et al. Biomarkers of oxidative stress study III. Effects of the nonsteroidal anti-inflammatory agents indomethacin and meclofenamic acid on measurements of oxidative products of lipids in CCl4 poisoning. Free Radical Biology & Medicine. 38: 711-8. PMID 15721981 DOI: 10.1016/j.freeradbiomed.2004.10.024  1
2005 Kadiiska MB, Gladen BC, Baird DD, Germolec D, Graham LB, Parker CE, Nyska A, Wachsman JT, Ames BN, Basu S, Brot N, Fitzgerald GA, Floyd RA, George M, Heinecke JW, et al. Biomarkers of oxidative stress study II: are oxidation products of lipids, proteins, and DNA markers of CCl4 poisoning? Free Radical Biology & Medicine. 38: 698-710. PMID 15721980 DOI: 10.1016/j.freeradbiomed.2004.09.017  1
2005 Egan KM, Wang M, Fries S, Lucitt MB, Zukas AM, Puré E, Lawson JA, FitzGerald GA. Cyclooxygenases, thromboxane, and atherosclerosis: plaque destabilization by cyclooxygenase-2 inhibition combined with thromboxane receptor antagonism. Circulation. 111: 334-42. PMID 15655126 DOI: 10.1161/01.CIR.0000153386.95356.78  1
2005 Furberg CD, Psaty BM, FitzGerald GA. Parecoxib, valdecoxib, and cardiovascular risk. Circulation. 111: 249. PMID 15655125 DOI: 10.1161/01.CIR.0000155081.76164.17  1
2005 Pini B, Grosser T, Lawson JA, Price TS, Pack MA, FitzGerald GA. Prostaglandin E synthases in zebrafish. Arteriosclerosis, Thrombosis, and Vascular Biology. 25: 315-20. PMID 15576635 DOI: 10.1161/01.ATV.0000152355.97808.10  1
2005 Chang CT, Jacobo SH, Powell WS, Lawson JA, FitzGerald GA, Pratico D, Rokach J. A new synthetic approach for 4(S)-hydroxycyclopent-2-enone: A precursor to prostanoid synthesis Tetrahedron Letters. 46: 6325-6328. DOI: 10.1016/j.tetlet.2005.07.035  1
2005 Francois H, Athirakul K, Howell D, Dash R, Mao L, Kim HS, Rockman HA, FitzGerald GA, Koller BH, Coffman TM. NSAIDs and cardiovascular risk - Reply [2] Cell Metabolism. 2: 339-340. DOI: 10.1016/j.cmet.2005.11.009  1
2005 Patrono C, Coller B, Fitzgerald GA, Hirsh J, Roth G. VI. Antiplatelet treatments | VI. Traitements antiplaquettaires Journal Des Maladies Vasculaires. 30: 2S44-2S49.  1
2004 Egan KM, Lawson JA, Fries S, Koller B, Rader DJ, Smyth EM, Fitzgerald GA. COX-2-derived prostacyclin confers atheroprotection on female mice. Science (New York, N.Y.). 306: 1954-7. PMID 15550624 DOI: 10.1126/science.1103333  1
2004 Hui Y, Cheng Y, Smalera I, Jian W, Goldhahn L, Fitzgerald GA, Funk CD. Directed vascular expression of human cysteinyl leukotriene 2 receptor modulates endothelial permeability and systemic blood pressure. Circulation. 110: 3360-6. PMID 15545522 DOI: 10.1161/01.CIR.0000147775.50954.AA  1
2004 Rudic RD, McNamara P, Curtis AM, Boston RC, Panda S, Hogenesch JB, Fitzgerald GA. BMAL1 and CLOCK, two essential components of the circadian clock, are involved in glucose homeostasis. Plos Biology. 2: e377. PMID 15523558 DOI: 10.1371/journal.pbio.0020377  1
2004 Fitzgerald GA. Coxibs and cardiovascular disease. The New England Journal of Medicine. 351: 1709-11. PMID 15470192 DOI: 10.1056/NEJMp048288  1
2004 Hashimoto K, Graham BS, Geraci MW, FitzGerald GA, Egan K, Zhou W, Goleniewska K, O'Neal JF, Morrow JD, Durbin RK, Wright PF, Collins RD, Suzutani T, Peebles RS. Signaling through the prostaglandin I2 receptor IP protects against respiratory syncytial virus-induced illness. Journal of Virology. 78: 10303-9. PMID 15367596 DOI: 10.1128/JVI.78.19.10303-10309.2004  1
2004 Sato TK, Panda S, Miraglia LJ, Reyes TM, Rudic RD, McNamara P, Naik KA, FitzGerald GA, Kay SA, Hogenesch JB. A functional genomics strategy reveals Rora as a component of the mammalian circadian clock. Neuron. 43: 527-37. PMID 15312651 DOI: 10.1016/j.neuron.2004.07.018  0.92
2004 Praticò D, Rokach J, Lawson J, FitzGerald GA. F2-isoprostanes as indices of lipid peroxidation in inflammatory diseases. Chemistry and Physics of Lipids. 128: 165-71. PMID 15037161 DOI: 10.1016/j.chemphyslip.2003.09.012  1
2004 Rokach J, Kim S, Bellone S, Lawson JA, Praticò D, Powell WS, FitzGerald GA. Total synthesis of isoprostanes: discovery and quantitation in biological systems. Chemistry and Physics of Lipids. 128: 35-56. PMID 15037151 DOI: 10.1016/j.chemphyslip.2003.09.011  1
2004 Kothapalli D, Fuki I, Ali K, Stewart SA, Zhao L, Yahil R, Kwiatkowski D, Hawthorne EA, FitzGerald GA, Phillips MC, Lund-Katz S, Puré E, Rader DJ, Assoian RK. Antimitogenic effects of HDL and APOE mediated by Cox-2-dependent IP activation. The Journal of Clinical Investigation. 113: 609-18. PMID 14966570 DOI: 10.1172/JCI19097  1
2004 Curtis AM, Seo SB, Westgate EJ, Rudic RD, Smyth EM, Chakravarti D, FitzGerald GA, McNamara P. Histone acetyltransferase-dependent chromatin remodeling and the vascular clock. The Journal of Biological Chemistry. 279: 7091-7. PMID 14645221 DOI: 10.1074/jbc.M311973200  1
2003 Ide T, Egan K, Bell-Parikh LC, FitzGerald GA. Activation of nuclear receptors by prostaglandins. Thrombosis Research. 110: 311-5. PMID 14592554 DOI: 10.1016/S0049-3848(03)00418-3  1
2003 Bell-Parikh LC, Ide T, Lawson JA, McNamara P, Reilly M, FitzGerald GA. Biosynthesis of 15-deoxy-delta12,14-PGJ2 and the ligation of PPARgamma. The Journal of Clinical Investigation. 112: 945-55. PMID 12975479 DOI: 10.1172/JCI18012  1
2003 Zhang Z, Vezza R, Plappert T, McNamara P, Lawson JA, Austin S, Praticò D, Sutton MS, FitzGerald GA. COX-2-dependent cardiac failure in Gh/tTG transgenic mice. Circulation Research. 92: 1153-61. PMID 12702643 DOI: 10.1161/01.RES.0000071749.22027.45  0.56
2003 FitzGerald GA. Parsing an enigma: the pharmacodynamics of aspirin resistance. Lancet. 361: 542-4. PMID 12598136 DOI: 10.1016/S0140-6736(03)12560-3  1
2002 McNamara P, Lawson JA, Rokach J, FitzGerald GA. Isoprostane activation of the nuclear hormone receptor PPAR. Advances in Experimental Medicine and Biology. 507: 351-5. PMID 12664609  0.56
2002 Smyth EM, Austin SC, FitzGerald GA. Activation-dependent internalization of the human prostacyclin receptor. Advances in Experimental Medicine and Biology. 507: 295-301. PMID 12664600  1
2002 Smyth EM, FitzGerald GA. Human prostacyclin receptor. Vitamins and Hormones. 65: 149-65. PMID 12481546  1
2002 Simon LS, Smolen JS, Abramson SB, Appel G, Bombardier C, Brater DC, Breedveld FC, Brune K, Burmester GR, Crofford LJ, Dougados M, DuBois RN, Fitzgerald GA, Frishman W, García Rodríguez LA, et al. Controversies in COX-2 selective inhibition. The Journal of Rheumatology. 29: 1501-10. PMID 12136912  1
2002 FitzGerald GA. The choreography of cyclooxygenases in the kidney. The Journal of Clinical Investigation. 110: 33-4. PMID 12093885 DOI: 10.1172/JCI16044  1
2002 Grosser T, Yusuff S, Cheskis E, Pack MA, FitzGerald GA. Developmental expression of functional cyclooxygenases in zebrafish. Proceedings of the National Academy of Sciences of the United States of America. 99: 8418-23. PMID 12011329 DOI: 10.1073/pnas.112217799  1
2002 Cheng Y, Austin SC, Rocca B, Koller BH, Coffman TM, Grosser T, Lawson JA, FitzGerald GA. Role of prostacyclin in the cardiovascular response to thromboxane A2. Science (New York, N.Y.). 296: 539-41. PMID 11964481 DOI: 10.1126/science.1068711  0.6
2002 FitzGerald GA. Cardiovascular pharmacology of nonselective nonsteroidal anti-inflammatory drugs and coxibs: clinical considerations. The American Journal of Cardiology. 89: 26D-32D. PMID 11909558  1
2002 FitzGerald GA. Nonsteroidal anti-inflammatory drugs, coxibs, and cardio-renal physiology: a mechanism-based approach. The American Journal of Cardiology. 89: 1D-2D. PMID 11909554  1
2002 Kim S, Lawson JA, Praticò D, FitzGerald GA, Rokach J. The first total synthesis of iPF4α-VI and its deuterated analog Tetrahedron Letters. 43: 2801-2805. DOI: 10.1016/S0040-4039(02)00398-2  1
2001 FitzGerald GA. Bioactive lipids and atherothrombosis. Haematologica. 86: 3-7. PMID 11926771  1
2001 Al-Abed Y, VanPatten S, Li H, Lawson JA, FitzGerald GA, Manogue KR, Bucala R. Characterization of a novel hemoglobin-glutathione adduct that is elevated in diabetic patients. Molecular Medicine (Cambridge, Mass.). 7: 619-23. PMID 11778651  1
2001 Catella-Lawson F, Reilly MP, Kapoor SC, Cucchiara AJ, DeMarco S, Tournier B, Vyas SN, FitzGerald GA. Cyclooxygenase inhibitors and the antiplatelet effects of aspirin. The New England Journal of Medicine. 345: 1809-17. PMID 11752357 DOI: 10.1056/NEJMoa003199  1
2001 FitzGerald GA, Cheng Y, Austin S. COX-2 inhibitors and the cardiovascular system. Clinical and Experimental Rheumatology. 19: S31-6. PMID 11695249  0.6
2001 Cyrus T, Tang LX, Rokach J, FitzGerald GA, Praticò D. Lipid peroxidation and platelet activation in murine atherosclerosis. Circulation. 104: 1940-5. PMID 11602498  1
2001 McNamara P, FitzGerald GA. Smoking-induced vascular disease: a new twist on an old theme. Circulation Research. 89: 563-5. PMID 11577020  1
2001 Regan CL, Levine RJ, Baird DD, Ewell MG, Martz KL, Sibai BM, Rokach J, Lawson JA, Fitzgerald GA. No evidence for lipid peroxidation in severe preeclampsia. American Journal of Obstetrics and Gynecology. 185: 572-8. PMID 11568780 DOI: 10.1067/mob.2001.116754  1
2001 Catella-Lawson F, Kapoor S, Moretti D, De Marco S, Vigilante GJ, Cucchiara AJ, Ramsey KE, Combe S, Rocca B, Theroux P, FitzGerald GA. Oral glycoprotein IIb/IIIa antagonism in patients with coronary artery disease. The American Journal of Cardiology. 88: 236-42. PMID 11472700 DOI: 10.1016/S0002-9149(01)01632-0  1
2001 Praticò D, Lawson JA, Rokach J, FitzGerald GA. The isoprostanes in biology and medicine. Trends in Endocrinology and Metabolism: Tem. 12: 243-7. PMID 11445440  1
2001 McNamara P, Seo SB, Rudic RD, Sehgal A, Chakravarti D, FitzGerald GA. Regulation of CLOCK and MOP4 by nuclear hormone receptors in the vasculature: a humoral mechanism to reset a peripheral clock. Cell. 105: 877-89. PMID 11439184 DOI: 10.1016/S0092-8674(01)00401-9  1
2001 Vezza R, Rokach J, FitzGerald GA. Prostaglandin F(2alpha) receptor-dependent regulation of prostaglandin transport. Molecular Pharmacology. 59: 1506-13. PMID 11353812 DOI: 10.1124/mol.59.6.1506  1
2001 Meagher EA, Barry OP, Lawson JA, Rokach J, FitzGerald GA. Effects of vitamin E on lipid peroxidation in healthy persons. Jama. 285: 1178-82. PMID 11231747  1
2001 Kim S, Jung YJ, Lawson JA, FitzGerald GA, Rokach J. iPF2α-III metabolism. First total synthesis of 2,3-dinor iPF2α-III, a primary β-oxidation metabolite Tetrahedron Letters. 42: 8277-8280. DOI: 10.1016/S0040-4039(01)01794-4  1
2000 FitzGerald GA, Austin S, Egan K, Cheng Y, Pratico D. Cyclo-oxygenase products and atherothrombosis. Annals of Medicine. 32: 21-6. PMID 11209977  1
2000 Praticó D, Cheng Y, FitzGerald GA. TP or not TP: primary mediators in a close runoff? Arteriosclerosis, Thrombosis, and Vascular Biology. 20: 1695-8. PMID 10894803  0.6
2000 Smyth EM, Austin SC, Reilly MP, FitzGerald GA. Internalization and sequestration of the human prostacyclin receptor. The Journal of Biological Chemistry. 275: 32037-45. PMID 10889200 DOI: 10.1074/jbc.M003873200  1
2000 McAdam BF, Mardini IA, Habib A, Burke A, Lawson JA, Kapoor S, FitzGerald GA. Effect of regulated expression of human cyclooxygenase isoforms on eicosanoid and isoeicosanoid production in inflammation. The Journal of Clinical Investigation. 105: 1473-82. PMID 10811855 DOI: 10.1172/JCI9523  1
2000 Weinstein EA, Li H, Lawson JA, Rokach J, FitzGerald GA, Axelsen PH. Prothrombinase acceleration by oxidatively damaged phospholipids. The Journal of Biological Chemistry. 275: 22925-30. PMID 10801844 DOI: 10.1074/jbc.M002438200  1
2000 Burke A, Lawson JA, Meagher EA, Rokach J, FitzGerald GA. Specific analysis in plasma and urine of 2,3-dinor-5, 6-dihydro-isoprostane F(2alpha)-III, a metabolite of isoprostane F(2alpha)-III and an oxidation product of gamma-linolenic acid. The Journal of Biological Chemistry. 275: 2499-504. PMID 10644705 DOI: 10.1074/jbc.275.4.2499  1
1999 Li H, Lawson JA, Reilly M, Adiyaman M, Hwang SW, Rokach J, FitzGerald GA. Quantitative high performance liquid chromatography/tandem mass spectrometric analysis of the four classes of F(2)-isoprostanes in human urine. Proceedings of the National Academy of Sciences of the United States of America. 96: 13381-6. PMID 10557329 DOI: 10.1073/pnas.96.23.13381  1
1999 Meagher EA, Barry OP, Burke A, Lucey MR, Lawson JA, Rokach J, FitzGerald GA. Alcohol-induced generation of lipid peroxidation products in humans. The Journal of Clinical Investigation. 104: 805-13. PMID 10491416 DOI: 10.1172/JCI5584  1
1999 Lawson JA, Rokach J, FitzGerald GA. Isoprostanes: formation, analysis and use as indices of lipid peroxidation in vivo. The Journal of Biological Chemistry. 274: 24441-4. PMID 10455102 DOI: 10.1074/jbc.274.35.24441  1
1999 Rocca B, Spain LM, Puré E, Langenbach R, Patrono C, FitzGerald GA. Distinct roles of prostaglandin H synthases 1 and 2 in T-cell development. The Journal of Clinical Investigation. 103: 1469-77. PMID 10330429 DOI: 10.1172/JCI6400  1
1999 Catella-Lawson F, McAdam B, Morrison BW, Kapoor S, Kujubu D, Antes L, Lasseter KC, Quan H, Gertz BJ, FitzGerald GA. Effects of specific inhibition of cyclooxygenase-2 on sodium balance, hemodynamics, and vasoactive eicosanoids. The Journal of Pharmacology and Experimental Therapeutics. 289: 735-41. PMID 10215647  1
1999 Rocca B, Spain LM, Ciabattoni G, Patrono C, FitzGerald GA. Differential expression and regulation of cyclooxygenase isozymes in thymic stromal cells. Journal of Immunology (Baltimore, Md. : 1950). 162: 4589-97. PMID 10201998  1
1999 Al-Abed Y, Mitsuhashi T, Li H, Lawson JA, FitzGerald GA, Founds H, Donnelly T, Cerami A, Ulrich P, Bucala R. Inhibition of advanced glycation endproduct formation by acetaldehyde: role in the cardioprotective effect of ethanol. Proceedings of the National Academy of Sciences of the United States of America. 96: 2385-90. PMID 10051651 DOI: 10.1073/pnas.96.5.2385  1
1999 McAdam BF, Catella-Lawson F, Mardini IA, Kapoor S, Lawson JA, FitzGerald GA. Systemic biosynthesis of prostacyclin by cyclooxygenase (COX)-2: the human pharmacology of a selective inhibitor of COX-2. Proceedings of the National Academy of Sciences of the United States of America. 96: 272-7. PMID 9874808 DOI: 10.1073/pnas.96.1.272  1
1999 Hwang SW, Adiyaman M, Lawson JA, FitzGerald GA, Rokach J. Synthesis of iPF(2α)-V: A new route Tetrahedron Letters. 40: 6167-6170. DOI: 10.1016/S0040-4039(99)01144-2  1
1998 Reilly MP, Praticò D, Delanty N, DiMinno G, Tremoli E, Rader D, Kapoor S, Rokach J, Lawson J, FitzGerald GA. Increased formation of distinct F2 isoprostanes in hypercholesterolemia. Circulation. 98: 2822-8. PMID 9860782 DOI: 10.1161/01.CIR.98.25.2822  0.52
1998 Praticò D, MY Lee V, Trojanowski JQ, Rokach J, Fitzgerald GA. Increased F2-isoprostanes in Alzheimer's disease: evidence for enhanced lipid peroxidation in vivo. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 12: 1777-83. PMID 9837868  1
1998 Lawson JA, Li H, Rokach J, Adiyaman M, Hwang SW, Khanapure SP, FitzGerald GA. Identification of two major F2 isoprostanes, 8,12-iso- and 5-epi-8, 12-iso-isoprostane F2alpha-VI, in human urine. The Journal of Biological Chemistry. 273: 29295-301. PMID 9792628 DOI: 10.1074/jbc.273.45.29295  1
1998 Baughman RA, Kapoor SC, Agarwal RK, Kisicki J, Catella-Lawson F, FitzGerald GA. Oral delivery of anticoagulant doses of heparin. A randomized, double-blind, controlled study in humans. Circulation. 98: 1610-5. PMID 9778325  1
1998 Praticò D, Tangirala RK, Rader DJ, Rokach J, FitzGerald GA. Vitamin E suppresses isoprostane generation in vivo and reduces atherosclerosis in ApoE-deficient mice. Nature Medicine. 4: 1189-92. PMID 9771755 DOI: 10.1038/2685  1
1998 Adiyaman M, Lawson JA, Khanapure SP, FitzGerald GA, Rokach J. Total synthesis of 17,17,18,18-d4-iPF2alpha-VI and quantification of iPF2alpha-VI in human urine by gas chromatography/mass spectrometry. Analytical Biochemistry. 262: 45-56. PMID 9735147 DOI: 10.1006/abio.1998.2767  1
1998 Smyth EM, Li WH, FitzGerald GA. Phosphorylation of the prostacyclin receptor during homologous desensitization. A critical role for protein kinase c. The Journal of Biological Chemistry. 273: 23258-66. PMID 9722557 DOI: 10.1074/jbc.273.36.23258  1
1998 Kunapuli P, Lawson JA, Rokach JA, Meinkoth JL, FitzGerald GA. Prostaglandin F2alpha (PGF2alpha) and the isoprostane, 8, 12-iso-isoprostane F2alpha-III, induce cardiomyocyte hypertrophy. Differential activation of downstream signaling pathways. The Journal of Biological Chemistry. 273: 22442-52. PMID 9712868 DOI: 10.1074/jbc.273.35.22442  1
1998 Rader DJ, FitzGerald GA. State of the art: atherosclerosis in a limited edition. Nature Medicine. 4: 899-900. PMID 9701240 DOI: 10.1038/nm0898-899  1
1998 Praticò D, Barry OP, Lawson JA, Adiyaman M, Hwang SW, Khanapure SP, Iuliano L, Rokach J, FitzGerald GA. IPF2alpha-I: an index of lipid peroxidation in humans. Proceedings of the National Academy of Sciences of the United States of America. 95: 3449-54. PMID 9520386 DOI: 10.1073/PNAS.95.7.3449  0.44
1998 Reilly MP, Lawson JA, FitzGerald GA. Eicosanoids and isoeicosanoids: indices of cellular function and oxidant stress. The Journal of Nutrition. 128: 434S-438S. PMID 9478043  1
1998 Seery LT, Nestor PV, FitzGerald GA. Molecular evolution of the aldo-keto reductase gene superfamily. Journal of Molecular Evolution. 46: 139-46. PMID 9452515  0.6
1998 Adiyaman M, Lawson JA, FitzGerald GA, Rokach J. Syntheses and identification of the most abundant urinary type VI isoprostanes Tetrahedron Letters. 39: 7039-7042. DOI: 10.1016/S0040-4039(98)01524-X  1
1997 Rokach J, Khanapure SP, Hwang SW, Adiyaman M, Lawson JA, FitzGerald GA. Nomenclature of isoprostanes: a proposal. Prostaglandins. 54: 853-73. PMID 9533181 DOI: 10.1016/S0090-6980(97)00184-6  1
1997 Rokach J, Khanapure SP, Hwang SW, Adiyaman M, Lawson JA, FitzGerald GA. The isoprostanes: a perspective. Prostaglandins. 54: 823-51. PMID 9533180 DOI: 10.1016/S0090-6980(97)00183-4  1
1997 Reilly MP, Delanty N, Roy L, Rokach J, Callaghan PO, Crean P, Lawson JA, FitzGerald GA. Increased formation of the isoprostanes IPF2alpha-I and 8-epi-prostaglandin F2alpha in acute coronary angioplasty: evidence for oxidant stress during coronary reperfusion in humans. Circulation. 96: 3314-20. PMID 9396422 DOI: 10.1161/01.CIR.96.10.3314  0.52
1997 Kunapuli P, Lawson JA, Rokach J, FitzGerald GA. Functional characterization of the ocular prostaglandin f2alpha (PGF2alpha) receptor. Activation by the isoprostane, 12-iso-PGF2alpha. The Journal of Biological Chemistry. 272: 27147-54. PMID 9341156 DOI: 10.1074/jbc.272.43.27147  1
1997 Praticò D, Iuliano L, Mauriello A, Spagnoli L, Lawson JA, Rokach J, Maclouf J, Violi F, FitzGerald GA. Localization of distinct F2-isoprostanes in human atherosclerotic lesions. The Journal of Clinical Investigation. 100: 2028-34. PMID 9329967 DOI: 10.1172/JCI119735  1
1997 FitzGerald GA, Tigges J, Barry P, Lawson JA. Markers of platelet activation and oxidant stress in atherothrombotic disease. Thrombosis and Haemostasis. 78: 280-4. PMID 9198167  1
1997 Delanty N, Reilly MP, Pratico D, Lawson JA, McCarthy JF, Wood AE, Ohnishi ST, Fitzgerald DJ, FitzGerald GA. 8-epi PGF2 alpha generation during coronary reperfusion. A potential quantitative marker of oxidant stress in vivo. Circulation. 95: 2492-9. PMID 9184579 DOI: 10.1161/01.CIR.95.11.2492  0.52
1997 Praticò D, Reilly M, Lawson JA, FitzGerald GA. Novel indices of oxidant stress in cardiovascular disease: specific analysis of F2-isoprostanes. Agents and Actions. Supplements. 48: 25-41. PMID 9177098  1
1997 Barry OP, Pratico D, Lawson JA, FitzGerald GA. Transcellular activation of platelets and endothelial cells by bioactive lipids in platelet microparticles. The Journal of Clinical Investigation. 99: 2118-27. PMID 9151784 DOI: 10.1172/JCI119385  1
1997 Adiyaman M, Li H, Lawson JA, Hwang SW, Khanapure SP, FitzGerald GA, Rokach J. First total synthesis of isoprostane IPF(2α)-III Tetrahedron Letters. 38: 3339-3342. DOI: 10.1016/S0040-4039(97)00622-9  1
1996 FitzGerald GA. The human pharmacology of thrombin inhibition. Coronary Artery Disease. 7: 911-8. PMID 9116934  1
1996 Smyth EM, Nestor PV, FitzGerald GA. Agonist-dependent phosphorylation of an epitope-tagged human prostacyclin receptor. The Journal of Biological Chemistry. 271: 33698-704. PMID 8969241 DOI: 10.1074/jbc.271.52.33698  1
1996 Reilly M, Delanty N, Lawson JA, FitzGerald GA. Modulation of oxidant stress in vivo in chronic cigarette smokers. Circulation. 94: 19-25. PMID 8964113  0.44
1996 Vezza R, Habib A, Li H, Lawson JA, FitzGerald GA. Regulation of cyclooxygenases by protein kinase C. Evidence against the importance of direct enzyme phosphorylation. The Journal of Biological Chemistry. 271: 30028-33. PMID 8939949 DOI: 10.1074/jbc.271.47.30028  1
1996 Delanty N, Reilly M, Pratico D, FitzGerald DJ, Lawson JA, FitzGerald GA. 8-Epi PGF2 alpha: specific analysis of an isoeicosanoid as an index of oxidant stress in vivo. British Journal of Clinical Pharmacology. 42: 15-9. PMID 8807139 DOI: 10.1046/J.1365-2125.1996.03804.X  1
1996 Praticò D, Smyth EM, Violi F, FitzGerald GA. Local amplification of platelet function by 8-Epi prostaglandin F2alpha is not mediated by thromboxane receptor isoforms. The Journal of Biological Chemistry. 271: 14916-24. PMID 8663015  1
1996 Adiyaman M, Lawson JA, Hwang SW, Khanapure SP, FitzGerald GA, Rokach J. Total synthesis of a novel isoprostane IPF(2α)-I and its identification in biological fluids Tetrahedron Letters. 37: 4849-4852. DOI: 10.1016/0040-4039(96)00973-2  1
1995 Catella F, Reilly MP, Delanty N, Lawson JA, Moran N, Meagher E, FitzGerald GA. Physiological formation of 8-epi-PGF2 alpha in vivo is not affected by cyclooxygenase inhibition. Advances in Prostaglandin, Thromboxane, and Leukotriene Research. 23: 233-6. PMID 7732842  1
1995 Pratico D, Lawson JA, Fitzgerald GA. Cyclooxygenase dependent formation of 8-iso-prostaglandin F2 alpha by human platelets. Advances in Prostaglandin, Thromboxane, and Leukotriene Research. 23: 229-31. PMID 7732840  1
1995 Pratico D, Lawson JA, FitzGerald GA. Cyclooxygenase-dependent formation of the isoprostane, 8-epi prostaglandin F2 alpha. The Journal of Biological Chemistry. 270: 9800-8. PMID 7730359 DOI: 10.1074/JBC.270.17.9800  1
1994 Nordøy A, Hatcher L, Goodnight S, Fitzgerald GA, Conner WE. Effects of dietary fat content, saturated fatty acids, and fish oil on eicosanoid production and hemostatic parameters in normal men. The Journal of Laboratory and Clinical Medicine. 123: 914-20. PMID 8201271  1
1994 Kinsella BT, O'Mahony D, Lawson JA, Pratico D, Fitzgerald GA. Cellular activation of thromboxane receptors. Annals of the New York Academy of Sciences. 714: 270-8. PMID 8017778 DOI: 10.1111/j.1749-6632.1994.tb12054.x  1
1994 Pratico D, Lawson JA, Fitzgerald GA. Cyclooxygenase-dependent formation of the isoprostane 8-epi prostaglandin F2 alpha. Annals of the New York Academy of Sciences. 744: 139-45. PMID 7825834 DOI: 10.1111/j.1749-6632.1994.tb52730.x  1
1993 Sorensen JD, Olsen SF, Pedersen AK, Boris J, Secher NJ, FitzGerald GA. Effects of fish oil supplementation in the third trimester of pregnancy on prostacyclin and thromboxane production American Journal of Obstetrics and Gynecology. 168: 915-922. PMID 8456902 DOI: 10.1016/S0002-9378(12)90845-5  1
1993 Harker LA, Kelly AB, Hanson SR, Krupski W, Bass A, Osterud B, FitzGerald GA, Goodnight SH, Connor WE. Interruption of vascular thrombus formation and vascular lesion formation by dietary n-3 fatty acids in fish oil in nonhuman primates. Circulation. 87: 1017-29. PMID 8443878 DOI: 10.1161/01.CIR.87.3.1017  1
1991 FitzGerald GA. Mechanisms of platelet activation: Thromboxane A2 as an amplifying signal for other agonists The American Journal of Cardiology. 68. PMID 1892057 DOI: 10.1016/0002-9149(91)90379-Y  1
1991 Cotton RB, Haywood JL, FitzGerald GA. Symptomatic patent ductus arteriosus following prophylactic indomethacin. A clinical and biochemical appraisal. Biology of the Neonate. 60: 273-82. PMID 1790251 DOI: 10.1159/000243418  1
1990 Catella F, Lawson JA, FitzGerald DJ, Fitzgerald GA. Endogenous biosynthesis of arachidonic acid epoxides in humans: Increased formation in pregnancy-induced hypertension Proceedings of the National Academy of Sciences of the United States of America. 87: 5893-5897. PMID 2198572 DOI: 10.1073/pnas.87.15.5893  1
1990 FitzGerald GA. Ticlopidine in unstable angina. A more expensive aspirin? Circulation. 82: 296-298. PMID 2114237 DOI: 10.1161/01.CIR.82.1.296  1
1990 Braden GA, Knapp HR, Fitzgerald DJ, FitzGerald GA. Dietary fish oil accelerates the response to coronary thrombolysis with tissue-type plasminogen activator. Evidence for a modest platelet inhibitory effect in vivo Circulation. 82: 178-187. PMID 2114234 DOI: 10.1161/01.CIR.82.1.178  1
1989 Fitzgerald GA, Braden G, Fitzgerald DJ, Knapp HR. Fish oils in cardiovascular disease Journal of Internal Medicine. 225: 25-29. PMID 2650696 DOI: 10.1111/j.1365-2796.1989.tb01432.x  1
1988 Alessandrini P, McRae J, Feman S, FitzGerald GA. Thromboxane biosynthesis and platelet function in Type I diabetes mellitus New England Journal of Medicine. 319: 208-212. PMID 3292913 DOI: 10.1056/NEJM198807283190404  1
1986 Catella F, Healy D, Lawson JA, FitzGerald GA. 11-Dehydrothromboxane B2: A quantitative index of thromboxane A2 formation in the human circulation Proceedings of the National Academy of Sciences of the United States of America. 83: 5861-5865. PMID 3461463 DOI: 10.1073/PNAS.83.16.5861  1
1986 Lawson JA, Patrono C, Ciabattoni G, FitzGerald GA. Long-lived enzymatic metabolites of thromboxane B2 in the human circulation Analytical Biochemistry. 155: 198-205. PMID 3087234 DOI: 10.1016/0003-2697(86)90247-2  1
1986 Knapp HR, Reilly IAG, Alessandrini P, Fitzgerald GA. In vivo indexes of platelet and vascular function during fish-oil adminstration in patients with atherosclerosis New England Journal of Medicine. 314: 937-942. PMID 3007982 DOI: 10.1056/NEJM198604103141501  1
1985 Lawson JA, Brash AR, Doran J, FitzGerald GA. Measurement of urinary 2,3-dinor-thromboxane B2 and thromboxane B2 using bonded-phase phenylboronic acid columns and capillary gas chromatography-negative-ion chemical ionization mass spectrometry Analytical Biochemistry. 150: 463-470. PMID 4091270 DOI: 10.1016/0003-2697(85)90536-6  1
1984 Pedersen AK, Watson ML, Fitzgerald GA. Inhibition of thromboxane biosynthesis in serum: Limitations of the measurement of immunoreactive 6-KETO-PGF1α Thrombosis Research. 33: 99-103. PMID 6546456 DOI: 10.1016/0049-3848(84)90159-2  1
1984 Watson ML, Goodman RP, Gill JR, Branch RA, Brash AR, Fitzgerald GA. Endogenous prostacyclin synthesis is decreased during activation of the renin-angiotensin system in man Journal of Clinical Endocrinology and Metabolism. 58: 304-308. PMID 6363436 DOI: 10.1210/jcem-58-2-304  0.44
1983 FitzGerald GA, Brash AR, Oates JA, Pedersen AK. Endogenous prostacyclin biosynthesis and platelet function during selective inhibition of thromboxane synthase in man. The Journal of Clinical Investigation. 72: 1336-43. PMID 6355181 DOI: 10.1172/JCI111089  0.44
1981 Hossman V, Heinen A, Auel H, FitzGerald GA. A randomized, placebo controlled trial of prostacyclin (PGI2) in peripheral arterial disease. Thrombosis Research. 22: 481-90. PMID 7027528 DOI: 10.1016/0049-3848(81)90109-2  1
1981 FitzGerald GA, Watkins J, Dollery CT. Regulation of norepinephrine release by peripheral α2-receptor stimulation Clinical Pharmacology and Therapeutics. 29: 160-167. PMID 6257444 DOI: 10.1038/clpt.1981.26  1
1980 Fitzgerald GA, Hamilton CA, Jones DH, Reid JL. Erythrocyte catechol-O-methyltransferase activity and indices of sympathetic activity in man Clinical Science. 58: 423-425. PMID 7190087 DOI: 10.1042/CS0580423  1
1980 Fitzgerald GA, Barnes P, Hamilton CA, Dollery CT. Circulating adrenaline and blood pressure: The metabolic effects and kinetics of infused adrenaline in man European Journal of Clinical Investigation. 10: 401-406. PMID 6777175 DOI: 10.1111/j.1365-2362.1980.tb00052.x  1
1980 Watkins J, FitzGerald G, Zamboulis C, Brown MJ, Dollery CT. Absence of opiate and histamine H2 receptor-mediated effects of clonidine. Clinical Pharmacology and Therapeutics. 28: 605-10. PMID 6254720  1
1979 FitzGerald GA. Neurogenic aspects of essential hypertension in man Irish Journal of Medical Science. 148: 280-289. PMID 397206 DOI: 10.1007/BF02938100  1
1979 Fitzgerald G, Petrie A. ANALYSIS OF EFFICACY OF ANTIHYPERTENSIVE DRUGS The Lancet. 313: 874. PMID 86117 DOI: 10.1016/S0140-6736(79)91286-8  1
1978 Fitzgerald GA. HYPERTENSIVE RESPONSE TO LABETALOL IN PHÆOCHROMOCYTOMA The Lancet. 311: 1259. PMID 78019 DOI: 10.1016/S0140-6736(78)92491-1  1
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