| Year |
Citation |
Score |
| 2023 |
Maltais JS, Lord-Dufour S, Morasse A, Stuible M, Loignon M, Durocher Y. Repressing expression of difficult-to-express recombinant proteins during the selection process increases productivity of CHO stable pools. Biotechnology and Bioengineering. PMID 37232536 DOI: 10.1002/bit.28435 |
0.327 |
|
| 2020 |
Abe KT, Li Z, Samson R, Samavarchi-Tehrani P, Valcourt EJ, Wood H, Budylowski P, Dupuis Ii AP, Girardin RC, Rathod B, Wang J, Barrios-Rodiles M, Colwill K, McGeer A, Mubareka S, ... ... Durocher Y, et al. A simple protein-based surrogate neutralization assay for SARS-CoV-2. Jci Insight. PMID 32870820 DOI: 10.1172/Jci.Insight.142362 |
0.335 |
|
| 2020 |
Srirangan K, Loignon M, Durocher Y. The use of site-specific recombination and cassette exchange technologies for monoclonal antibody production in Chinese Hamster ovary cells: retrospective analysis and future directions. Critical Reviews in Biotechnology. 1-19. PMID 32456474 DOI: 10.1080/07388551.2020.1768043 |
0.397 |
|
| 2019 |
Lalonde ME, Koyuturk I, Brochu D, Jabbour J, Gilbert M, Durocher Y. Production of α2,6-sialylated and non-fucosylated recombinant alpha-1-antitrypsin in CHO cells. Journal of Biotechnology. PMID 31697975 DOI: 10.1016/J.Jbiotec.2019.10.021 |
0.378 |
|
| 2019 |
Mellahi K, Brochu D, Gilbert M, Perrier M, Ansorge S, Durocher Y, Henry O. Assessment of Fed-batch Cultivation Strategies for an Inducible CHO Cell Line. Journal of Biotechnology. PMID 30959136 DOI: 10.1016/J.Jbiotec.2019.04.005 |
0.392 |
|
| 2019 |
Poulain A, Mullick A, Massie B, Durocher Y. Reducing recombinant protein expression during CHO pool selection enhances frequency of high-producing cells. Journal of Biotechnology. PMID 30885656 DOI: 10.1016/J.Jbiotec.2019.03.009 |
0.422 |
|
| 2019 |
Cambay F, Henry O, Durocher Y, De Crescenzo G. Impact of N-glycosylation on Fcγ receptor / IgG interactions: unravelling differences with an enhanced surface plasmon resonance biosensor assay based on coiled-coil interactions. Mabs. PMID 30822189 DOI: 10.1080/19420862.2019.1581017 |
0.336 |
|
| 2019 |
D'Eall C, Pon RA, Rossotti MA, Krahn N, Spearman M, Callaghan D, van Faassen H, Hussack G, Stetefeld J, Butler M, Durocher Y, Zhang J, Henry KA, Tanha J. Modulation of antibody-dependent cellular cytotoxicity of EGFR-specific heavy-chain antibodies through hinge engineering. Immunology and Cell Biology. PMID 30680791 DOI: 10.1111/Imcb.12238 |
0.338 |
|
| 2019 |
Mellahi K, Brochu D, Gilbert M, Perrier M, Ansorge S, Durocher Y, Henry O. Process intensification for the production of rituximab by an inducible CHO cell line. Bioprocess and Biosystems Engineering. PMID 30673843 DOI: 10.1007/S00449-019-02075-Z |
0.403 |
|
| 2018 |
Bouvette J, Korkut DN, Fouillen A, Amellah S, Nanci A, Durocher Y, Omichinski JG, Legault P. High-yield production of human Dicer by transfection of human HEK293-EBNA1 cells grown in suspension. Bmc Biotechnology. 18: 76. PMID 30522464 DOI: 10.1186/S12896-018-0485-3 |
0.347 |
|
| 2018 |
Vaniotis G, Moffett S, Sulea T, Wang N, Elahi SM, Lessard E, Baardsnes J, Perrino S, Durocher Y, Frystyk J, Massie B, Brodt P. Enhanced anti-metastatic bioactivity of an IGF-TRAP re-engineered to improve physicochemical properties. Scientific Reports. 8: 17361. PMID 30478273 DOI: 10.1038/S41598-018-35407-2 |
0.311 |
|
| 2018 |
Mellahi K, Cambay F, Brochu D, Gilbert M, Perrier M, Ansorge S, Durocher Y, Henry O. Process Development for an Inducible Rituximab-Expressing CHO Cell Line. Biotechnology Progress. PMID 30414355 DOI: 10.1002/Btpr.2742 |
0.404 |
|
| 2018 |
L'Abbé D, Bisson L, Gervais C, Grazzini E, Durocher Y. Transient Gene Expression in Suspension HEK293-EBNA1 Cells. Methods in Molecular Biology (Clifton, N.J.). 1850: 1-16. PMID 30242676 DOI: 10.1007/978-1-4939-8730-6_1 |
0.436 |
|
| 2018 |
Stuible M, Burlacu A, Perret S, Brochu D, Paul-Roc B, Baardsnes J, Loignon M, Grazzini E, Durocher Y. OPTIMIZATION OF A HIGH-CELL-DENSITY POLYETHYLENIMINE TRANSFECTION METHOD FOR RAPID PROTEIN PRODUCTION IN CHO-EBNA1 CELLS. Journal of Biotechnology. PMID 29886030 DOI: 10.1016/J.Jbiotec.2018.06.307 |
0.452 |
|
| 2018 |
Karengera E, Robotham A, Kelly J, Durocher Y, De Crescenzo G, Henry O. Concomitant reduction of lactate and ammonia accumulation in fed-batch cultures: Impact on glycoprotein production and quality. Biotechnology Progress. PMID 29314777 DOI: 10.1002/Btpr.2607 |
0.361 |
|
| 2018 |
Stuible M, Lier Fv, Croughan MS, Durocher Y. Beyond preclinical research: production of CHO-derived biotherapeutics for toxicology and early-phase trials by transient gene expression or stable pools Current Opinion in Chemical Engineering. 22: 145-151. DOI: 10.1016/J.Coche.2018.09.010 |
0.374 |
|
| 2017 |
Escobar-Cabrera E, Lario P, Baardsnes J, Schrag J, Durocher Y, Dixit S. Asymmetric Fc Engineering for Bispecific Antibodies with Reduced Effector Function Antibodies. 6: 7. PMID 31548523 DOI: 10.3390/Antib6020007 |
0.323 |
|
| 2017 |
Karengera E, Durocher Y, De Crescenzo G, Henry O. Combining metabolic and process engineering strategies to improve recombinant glycoprotein production and quality. Applied Microbiology and Biotechnology. PMID 28924963 DOI: 10.1007/S00253-017-8513-0 |
0.421 |
|
| 2017 |
Henry KA, Kandalaft H, Lowden MJ, Rossotti MA, van Faassen H, Hussack G, Durocher Y, Kim DY, Tanha J. A disulfide-stabilized human VL single-domain antibody library is a source of soluble and highly thermostable binders. Molecular Immunology. 90: 190-196. PMID 28820969 DOI: 10.1016/J.Molimm.2017.07.006 |
0.358 |
|
| 2017 |
Vivcharuk V, Baardsnes J, Deprez C, Sulea T, Jaramillo M, Corbeil CR, Mullick A, Magoon J, Marcil A, Durocher Y, O'Connor-McCourt MD, Purisima EO. Assisted Design of Antibody and Protein Therapeutics (ADAPT). Plos One. 12: e0181490. PMID 28750054 DOI: 10.1371/Journal.Pone.0181490 |
0.336 |
|
| 2017 |
Manceur AP, Zou W, Marcil A, Paquet E, Gadoury C, Jaentschke B, Li X, Petiot E, Durocher Y, Baardsnes J, Rosa-Calatrava M, Ansorge S, Kamen AA. Generation of monoclonal pan-hemagglutinin antibodies for the quantification of multiple strains of influenza. Plos One. 12: e0180314. PMID 28662134 DOI: 10.1371/Journal.Pone.0180314 |
0.303 |
|
| 2017 |
Poulain A, Perret S, Malenfant F, Mullick A, Massie B, Durocher Y. Rapid protein production from stable CHO cell pools using plasmid vector and the cumate gene-switch. Journal of Biotechnology. 255: 16-27. PMID 28625678 DOI: 10.1016/J.Jbiotec.2017.06.009 |
0.439 |
|
| 2017 |
Madadkar P, Sadavarte R, Butler M, Durocher Y, Ghosh R. Preparative separation of monoclonal antibody aggregates by cation-exchange laterally-fed membrane chromatography. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. 1055: 158-164. PMID 28477519 DOI: 10.1016/J.Jchromb.2017.04.036 |
0.328 |
|
| 2017 |
Lalonde M, Durocher Y. Therapeutic glycoprotein production in mammalian cells Journal of Biotechnology. 251: 128-140. PMID 28465209 DOI: 10.1016/J.Jbiotec.2017.04.028 |
0.403 |
|
| 2017 |
Riahi N, Murschel F, Lerouge S, Durocher Y, Henry O, De Crescenzo G. Bioavailability of immobilized epidermal growth factor: Covalent versus noncovalent grafting. Biointerphases. 12: 010501. PMID 28325051 DOI: 10.1116/1.4978871 |
0.302 |
|
| 2017 |
Dorion-Thibaudeau J, Durocher Y, Crescenzo GD. Quantification and simultaneous evaluation of the bioactivity of antibody produced in CHO cell culture-The use of the ectodomain of FcγRI and surface plasmon resonance-based biosensor. Molecular Immunology. 82: 46-49. PMID 28012362 DOI: 10.1016/J.Molimm.2016.12.017 |
0.38 |
|
| 2016 |
Karengera E, Robotham A, Kelly J, Durocher Y, De Crescenzo G, Henry O. Altering the central carbon metabolism of HEK293 cells: Impact on recombinant glycoprotein quality. Journal of Biotechnology. PMID 27940295 DOI: 10.1016/J.Jbiotec.2016.12.003 |
0.4 |
|
| 2016 |
Krahn N, Spearman M, Meier M, Dorion-Thibaudeau J, McDougall M, Patel TR, De Crescenzo G, Durocher Y, Stetefeld J, Butler M. Inhibition of glycosylation on a camelid antibody uniquely affects its FcγRI binding activity. European Journal of Pharmaceutical Sciences : Official Journal of the European Federation For Pharmaceutical Sciences. PMID 27721040 DOI: 10.1016/J.Ejps.2016.09.040 |
0.345 |
|
| 2016 |
Blondeel EJ, Ho R, Schulze S, Sokolenko S, Guillemette SR, Slivac I, Durocher Y, Guillemette JG, McConkey BJ, Chang D, Aucoin MG. An Omics Approach to Rational Feed: Enhancing Growth in CHO Cultures with NMR Metabolomics and 2D-DIGE Proteomics. Journal of Biotechnology. PMID 27496566 DOI: 10.1016/J.Jbiotec.2016.07.027 |
0.398 |
|
| 2016 |
Delafosse L, Xu P, Durocher Y. Data on physicochemical properties of LPEI 25 kDa, PEI"Max" 40 kDa and PEIpro™. Data in Brief. 8: 456-60. PMID 27331123 DOI: 10.1016/J.Dib.2016.05.062 |
0.305 |
|
| 2016 |
Delafosse L, Xu P, Durocher Y. Comparative study of polyethylenimines for transient gene expression in mammalian HEK293 and CHO cells. Journal of Biotechnology. PMID 27085888 DOI: 10.1016/J.Jbiotec.2016.04.028 |
0.382 |
|
| 2016 |
Dorion-Thibaudeau J, St-Laurent G, Raymond C, De Crescenzo G, Durocher Y. Biotinylation of the Fcγ receptor ectodomains by mammalian cell co-transfection: application to the development of a surface plasmon resonance-based assay. Journal of Molecular Recognition : Jmr. 29: 60-9. PMID 26762306 DOI: 10.1002/Jmr.2495 |
0.366 |
|
| 2016 |
Toussaint C, Henry O, Durocher Y. Metabolic engineering of CHO cells to alter lactate metabolism during fed-batch cultures. Journal of Biotechnology. 217: 122-31. PMID 26603123 DOI: 10.1016/J.Jbiotec.2015.11.010 |
0.391 |
|
| 2016 |
O'Connor-McCourt MD, Lenferink AEG, Zwaagstra J, Sulea T, Baardsnes J, Collins C, Cantin C, Couture L, Tao L, Durocher Y, Singh R, Koropatnick J. Abstract B058: Development of AVID200, a novel and highly potent TGF-beta neutralizing immunotherapy Cancer Immunology Research. 4. DOI: 10.1158/2326-6066.Imm2016-B058 |
0.307 |
|
| 2016 |
O’Connor-McCourt MD, Lenferink AEG, Zwaagstra J, Sulea T, Baardsnes J, Collins C, Cantin C, Durocher Y, Singh R, Koropatnick J. Abstract 560: Development of a novel class of traps that potently block transforming growth factor-beta (TGF-beta) thereby counteracting TGF-beta mediated immunosuppression and promoting T-cell infiltration into tumors Cancer Research. 76: 560-560. DOI: 10.1158/1538-7445.Am2016-560 |
0.31 |
|
| 2015 |
Bodnar E, Raymond C, Lopez PG, Villacrés C, Butler M, Schoenhofen IC, Durocher Y, Perreault H. Mass spectrometric analysis of products of metabolic glycan engineering with azido-modification of sialic acids. Analytical and Bioanalytical Chemistry. PMID 26362153 DOI: 10.1007/S00216-015-9010-X |
0.37 |
|
| 2015 |
Fortier C, Louvier E, Durocher Y, De Crescenzo G. Tailoring the Surface of a Gene Delivery Vector with Carboxymethylated Dextran: A Systematic Analysis. Biomacromolecules. 16: 1671-81. PMID 25876439 DOI: 10.1021/Acs.Biomac.5B00221 |
0.313 |
|
| 2015 |
Raymond C, Robotham A, Spearman M, Butler M, Kelly J, Durocher Y. Production of α2,6-sialylated IgG1 in CHO cells. Mabs. 7: 571-83. PMID 25875452 DOI: 10.1080/19420862.2015.1029215 |
0.344 |
|
| 2015 |
Wang N, Rayes RF, Elahi SM, Lu Y, Hancock MA, Massie B, Rowe GE, Aomari H, Hossain S, Durocher Y, Pinard M, Tabariès S, Siegel PM, Brodt P. The IGF-Trap: Novel Inhibitor of Carcinoma Growth and Metastasis. Molecular Cancer Therapeutics. 14: 982-93. PMID 25673819 DOI: 10.1158/1535-7163.Mct-14-0751 |
0.354 |
|
| 2015 |
Khazaei MR, Montcalm S, Di Polo A, Fournier AE, Durocher Y, Ong Tone S. Development of a cell permeable competitive antagonist of RhoA and CRMP4 binding, TAT-C4RIP, to promote neurite outgrowth. Journal of Molecular Neuroscience : Mn. 55: 406-15. PMID 25015230 DOI: 10.1007/S12031-014-0350-3 |
0.4 |
|
| 2014 |
Dorion-Thibaudeau J, Raymond C, Lattová E, Perreault H, Durocher Y, De Crescenzo G. Towards the development of a surface plasmon resonance assay to evaluate the glycosylation pattern of monoclonal antibodies using the extracellular domains of CD16a and CD64. Journal of Immunological Methods. 408: 24-34. PMID 24810583 DOI: 10.1016/J.Jim.2014.04.010 |
0.349 |
|
| 2014 |
LeBlanc PM, Doggett TA, Choi J, Hancock MA, Durocher Y, Frank F, Nagar B, Ferguson TA, Saleh M. An immunogenic peptide in the A-box of HMGB1 protein reverses apoptosis-induced tolerance through RAGE receptor. The Journal of Biological Chemistry. 289: 7777-86. PMID 24474694 DOI: 10.1074/Jbc.M113.541474 |
0.325 |
|
| 2014 |
Vallée C, Durocher Y, Henry O. Exploiting the metabolism of PYC expressing HEK293 cells in fed-batch cultures. Journal of Biotechnology. 169: 63-70. PMID 24246270 DOI: 10.1016/J.Jbiotec.2013.11.002 |
0.409 |
|
| 2013 |
Mignaqui AC, Ruiz V, Perret S, St-Laurent G, Singh Chahal P, Transfiguracion J, Sammarruco A, Gnazzo V, Durocher Y, Wigdorovitz A. Transient gene expression in serum-free suspension-growing mammalian cells for the production of foot-and-mouth disease virus empty capsids. Plos One. 8: e72800. PMID 23977353 DOI: 10.1371/Journal.Pone.0072800 |
0.321 |
|
| 2013 |
Von Kreudenstein TS, Escobar-Carbrera E, Lario PI, D'Angelo I, Brault K, Kelly J, Durocher Y, Baardsnes J, Woods RJ, Xie MH, Girod PA, Suits MD, Boulanger MJ, Poon DK, Ng GY, et al. Improving biophysical properties of a bispecific antibody scaffold to aid developability: quality by molecular design. Mabs. 5: 646-54. PMID 23924797 DOI: 10.4161/Mabs.25632 |
0.337 |
|
| 2013 |
Moreno MJ, Ball M, Rukhlova M, Slinn J, L'abbe D, Iqbal U, Monette R, Hagedorn M, O'Connor-McCourt MD, Durocher Y, Stanimirovic DB. IGFBP-4 anti-angiogenic and anti-tumorigenic effects are associated with anti-cathepsin B activity. Neoplasia (New York, N.Y.). 15: 554-67. PMID 23633927 DOI: 10.1593/Neo.13212 |
0.348 |
|
| 2013 |
Murschel F, Liberelle B, St-Laurent G, Jolicoeur M, Durocher Y, De Crescenzo G. Coiled-coil-mediated grafting of bioactive vascular endothelial growth factor. Acta Biomaterialia. 9: 6806-13. PMID 23485856 DOI: 10.1016/J.Actbio.2013.02.032 |
0.344 |
|
| 2013 |
Fortier C, De Crescenzo G, Durocher Y. A versatile coiled-coil tethering system for the oriented display of ligands on nanocarriers for targeted gene delivery. Biomaterials. 34: 1344-53. PMID 23137397 DOI: 10.1016/J.Biomaterials.2012.10.047 |
0.346 |
|
| 2013 |
Srivastava A, Durocher Y, Gamain B. Expressing full-length functional PfEMP1 proteins in the HEK293 expression system. Methods in Molecular Biology (Clifton, N.J.). 923: 307-19. PMID 22990788 DOI: 10.1007/978-1-62703-026-7_22 |
0.341 |
|
| 2013 |
Jaramillo ML, Marcil A, Durocher Y, Gilbert R, Mullick A, Kelly J, O'Connor-McCourt M, Massie B. Abstract A248: Integrated therapeutic antibody development at the National Research Council of Canada. Molecular Cancer Therapeutics. 12. DOI: 10.1158/1535-7163.Targ-13-A248 |
0.377 |
|
| 2012 |
Agrawal V, Slivac I, Perret S, Bisson L, St-Laurent G, Murad Y, Zhang J, Durocher Y. Stable expression of chimeric heavy chain antibodies in CHO cells. Methods in Molecular Biology (Clifton, N.J.). 911: 287-303. PMID 22886259 DOI: 10.1007/978-1-61779-968-6_18 |
0.392 |
|
| 2012 |
Zwaagstra JC, Sulea T, Baardsnes J, Lenferink AE, Collins C, Cantin C, Paul-Roc B, Grothe S, Hossain S, Richer LP, L'Abbé D, Tom R, Cass B, Durocher Y, O'Connor-McCourt MD. Engineering and therapeutic application of single-chain bivalent TGF-β family traps. Molecular Cancer Therapeutics. 11: 1477-87. PMID 22562986 DOI: 10.1158/1535-7163.Mct-12-0060 |
0.334 |
|
| 2011 |
Swiech K, Kamen A, Ansorge S, Durocher Y, Picanço-Castro V, Russo-Carbolante EM, Neto MS, Covas DT. Transient transfection of serum-free suspension HEK 293 cell culture for efficient production of human rFVIII. Bmc Biotechnology. 11: 114. PMID 22115125 DOI: 10.1186/1472-6750-11-114 |
0.375 |
|
| 2011 |
Pen A, Durocher Y, Slinn J, Rukhlova M, Charlebois C, Stanimirovic DB, Moreno MJ. Insulin-like growth factor binding protein 7 exhibits tumor suppressive and vessel stabilization properties in U87MG and T98G glioblastoma cell lines. Cancer Biology & Therapy. 12: 634-46. PMID 21795858 DOI: 10.4161/Cbt.12.7.17171 |
0.365 |
|
| 2011 |
Henry O, Durocher Y. Enhanced glycoprotein production in HEK-293 cells expressing pyruvate carboxylase. Metabolic Engineering. 13: 499-507. PMID 21624497 DOI: 10.1016/J.Ymben.2011.05.004 |
0.399 |
|
| 2011 |
Raymond C, Tom R, Perret S, Moussouami P, L'Abbé D, St-Laurent G, Durocher Y. A simplified polyethylenimine-mediated transfection process for large-scale and high-throughput applications. Methods (San Diego, Calif.). 55: 44-51. PMID 21539918 DOI: 10.1016/J.Ymeth.2011.04.002 |
0.411 |
|
| 2011 |
Cass B, Pham PL, Kamen A, Durocher Y. Reprint of: Purification of recombinant proteins from mammalian cell culture using a generic double-affinity chromatography scheme Protein Expression and Purification. DOI: 10.1016/J.Pep.2011.08.012 |
0.425 |
|
| 2010 |
Liberelle B, Boucher C, Chen J, Jolicoeur M, Durocher Y, De Crescenzo G. Impact of epidermal growth factor tethering strategy on cellular response. Bioconjugate Chemistry. 21: 2257-66. PMID 21058714 DOI: 10.1021/Bc1002604 |
0.37 |
|
| 2010 |
Afkhami F, Durocher Y, Prakash S. Investigation of antiangiogenic tumor therapy potential of microencapsulated HEK293 VEGF165b producing cells. Journal of Biomedicine & Biotechnology. 2010: 645610. PMID 20976076 DOI: 10.1155/2010/645610 |
0.345 |
|
| 2010 |
Liberelle B, Bartholin L, Boucher C, Murschel F, Jolicoeur M, Durocher Y, Merzouki A, De Crescenzo G. New ELISA approach based on coiled-coil interactions. Journal of Immunological Methods. 362: 161-7. PMID 20869967 DOI: 10.1016/J.Jim.2010.09.027 |
0.327 |
|
| 2010 |
Male KB, Tom R, Durocher Y, Greer C, Luong JH. Noninvasive probing of inhibitory effects of cylindrospermopsin and microcystin-LR using cell-based impedance spectroscopy. Environmental Science & Technology. 44: 6775-81. PMID 20701281 DOI: 10.1021/Es101206T |
0.33 |
|
| 2010 |
Boucher C, Ruiz JC, Thibault M, Buschmann MD, Wertheimer MR, Jolicoeur M, Durocher Y, De Crescenzo G. Human corneal epithelial cell response to epidermal growth factor tethered via coiled-coil interactions. Biomaterials. 31: 7021-31. PMID 20579729 DOI: 10.1016/J.Biomaterials.2010.05.072 |
0.353 |
|
| 2010 |
Segura MM, Garnier A, Durocher Y, Ansorge S, Kamen A. New protocol for lentiviral vector mass production. Methods in Molecular Biology (Clifton, N.J.). 614: 39-52. PMID 20225034 DOI: 10.1007/978-1-60761-533-0_2 |
0.349 |
|
| 2010 |
Boucher C, St-Laurent G, Jolicoeur M, Crescenzo GD, Durocher Y. Protein detection by Western blot via coiled-coil interactions. Analytical Biochemistry. 399: 138-40. PMID 20005863 DOI: 10.1016/J.Ab.2009.12.007 |
0.313 |
|
| 2010 |
Lenferink AEG, Cantin C, Nantel A, Wang E, Durocher Y, Banville M, Paul-Roc B, Marcil A, Wilson MR, O'Connor-Mccourt MD. Transcriptome profiling of a TGF-Β-induced epithelial-to-mesenchymal transition reveals extracellular clusterin as a target for therapeutic antibodies Oncogene. 29: 831-844. PMID 19935703 DOI: 10.1038/Onc.2009.399 |
0.307 |
|
| 2010 |
Bell A, Wang ZJ, Arbabi-Ghahroudi M, Chang TA, Durocher Y, Trojahn U, Baardsnes J, Jaramillo ML, Li S, Baral TN, O'Connor-McCourt M, Mackenzie R, Zhang J. Differential tumor-targeting abilities of three single-domain antibody formats. Cancer Letters. 289: 81-90. PMID 19716651 DOI: 10.1016/J.Canlet.2009.08.003 |
0.347 |
|
| 2010 |
Henry O, Durocher Y. Engineering of the human cell line HEK-293 to enhance recombinant protein production Ifac Proceedings Volumes (Ifac-Papersonline). 11: 473-478. DOI: 10.3182/20100707-3-Be-2012.0110 |
0.401 |
|
| 2009 |
Durocher Y, Butler M. Expression systems for therapeutic glycoprotein production. Current Opinion in Biotechnology. 20: 700-7. PMID 19889531 DOI: 10.1016/J.Copbio.2009.10.008 |
0.431 |
|
| 2009 |
Ansorge S, Lanthier S, Transfiguracion J, Durocher Y, Henry O, Kamen A. Development of a scalable process for high-yield lentiviral vector production by transient transfection of HEK293 suspension cultures. The Journal of Gene Medicine. 11: 868-76. PMID 19618482 DOI: 10.1002/Jgm.1370 |
0.398 |
|
| 2009 |
Boucher C, Liberelle B, Jolicoeur M, Durocher Y, De Crescenzo G. Epidermal growth factor tethered through coiled-coil interactions induces cell surface receptor phosphorylation. Bioconjugate Chemistry. 20: 1569-77. PMID 19588921 DOI: 10.1021/Bc9001147 |
0.347 |
|
| 2009 |
Zhang J, MacKenzie R, Durocher Y. Production of chimeric heavy-chain antibodies. Methods in Molecular Biology (Clifton, N.J.). 525: 323-36, xv. PMID 19252853 DOI: 10.1007/978-1-59745-554-1_17 |
0.363 |
|
| 2009 |
Zhang J, Liu X, Bell A, To R, Baral TN, Azizi A, Li J, Cass B, Durocher Y. Transient expression and purification of chimeric heavy chain antibodies. Protein Expression and Purification. 65: 77-82. PMID 19007889 DOI: 10.1016/J.Pep.2008.10.011 |
0.367 |
|
| 2009 |
Dormond E, Meneses-Acosta A, Jacob D, Durocher Y, Gilbert R, Perrier M, Kamen A. An efficient and scalable process for helper-dependent adenoviral vector production using polyethylenimine-adenofection Biotechnology and Bioengineering. 102: 800-810. PMID 18821637 DOI: 10.1002/Bit.22113 |
0.379 |
|
| 2008 |
Tom R, Bisson L, Durocher Y. Purification of his-tagged proteins using fractogel-cobalt. Csh Protocols. 2008: pdb.prot4980. PMID 21356796 DOI: 10.1101/Pdb.Prot4980 |
0.358 |
|
| 2008 |
Tom R, Bisson L, Durocher Y. Transfection of HEK293-EBNA1 Cells in Suspension with 293fectin for Production of Recombinant Proteins. Csh Protocols. 2008: pdb.prot4979. PMID 21356795 |
0.304 |
|
| 2008 |
Tom R, Bisson L, Durocher Y. Transfection of Adherent HEK293-EBNA1 Cells in a Six-Well Plate with Branched PEI for Production of Recombinant Proteins. Csh Protocols. 2008: pdb.prot4978. PMID 21356794 DOI: 10.1101/Pdb.Prot4978 |
0.438 |
|
| 2008 |
Tom R, Bisson L, Durocher Y. Transfection of HEK293-EBNA1 Cells in Suspension with Linear PEI for Production of Recombinant Proteins. Csh Protocols. 2008: pdb.prot4977. PMID 21356793 DOI: 10.1101/Pdb.Prot4977 |
0.423 |
|
| 2008 |
Tom R, Bisson L, Durocher Y. Culture of HEK293-EBNA1 Cells for Production of Recombinant Proteins. Csh Protocols. 2008: pdb.prot4976. PMID 21356792 DOI: 10.1101/Pdb.Prot4976 |
0.425 |
|
| 2008 |
Loignon M, Perret S, Kelly J, Boulais D, Cass B, Bisson L, Afkhamizarreh F, Durocher Y. Stable high volumetric production of glycosylated human recombinant IFNalpha2b in HEK293 cells. Bmc Biotechnology. 8: 65. PMID 18752669 DOI: 10.1186/1472-6750-8-65 |
0.432 |
|
| 2008 |
Pen A, Moreno MJ, Durocher Y, Deb-Rinker P, Stanimirovic DB. Glioblastoma-secreted factors induce IGFBP7 and angiogenesis by modulating Smad-2-dependent TGF-beta signaling. Oncogene. 27: 6834-44. PMID 18711401 DOI: 10.1038/Onc.2008.287 |
0.348 |
|
| 2008 |
Demolliens A, Boucher C, Durocher Y, Jolicoeur M, Buschmann MD, De Crescenzo G. Tyrosinase-catalyzed synthesis of a universal coil-chitosan bioconjugate for protein immobilization. Bioconjugate Chemistry. 19: 1849-54. PMID 18700789 DOI: 10.1021/Bc800066B |
0.304 |
|
| 2008 |
Boucher C, St-Laurent G, Loignon M, Jolicoeur M, De Crescenzo G, Durocher Y. The bioactivity and receptor affinity of recombinant tagged EGF designed for tissue engineering applications is defined by the nature and position of the tags. Tissue Engineering. Part A. 14: 2069-77. PMID 18652537 DOI: 10.1089/Ten.Tea.2008.0037 |
0.377 |
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| 2008 |
Paris S, Burlacu A, Durocher Y. Opposing roles of syndecan-1 and syndecan-2 in polyethyleneimine-mediated gene delivery. The Journal of Biological Chemistry. 283: 7697-704. PMID 18216019 DOI: 10.1074/Jbc.M705424200 |
0.339 |
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| 2008 |
Broussau S, Jabbour N, Lachapelle G, Durocher Y, Tom R, Transfiguracion J, Gilbert R, Massie B. Inducible packaging cells for large-scale production of lentiviral vectors in serum-free suspension culture. Molecular Therapy : the Journal of the American Society of Gene Therapy. 16: 500-7. PMID 18180776 DOI: 10.1038/Sj.Mt.6300383 |
0.385 |
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| 2008 |
Meneses-Acosta A, Dormond E, Jacob D, Tom R, Bernier A, Perret S, St-Laurent G, Durocher Y, Gilbert R, Kamen A. Development of a suspension serum-free helper-dependent adenovirus production system and assessment of co-infection conditions. Journal of Virological Methods. 148: 106-14. PMID 18079009 DOI: 10.1016/J.Jviromet.2007.10.017 |
0.368 |
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| 2008 |
Jacquemart R, Chavane N, Durocher Y, Hoemann C, De Crescenzo G, Jolicoeur M. At-line monitoring of bioreactor protein production by Surface Plasmon Resonance. Biotechnology and Bioengineering. 100: 184-8. PMID 18023054 DOI: 10.1002/Bit.21725 |
0.352 |
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| 2008 |
Tom R, Bisson L, Durocher Y. Transfection of HEK293-EBNA1 cells in suspension with 293fectin for production of recombinant proteins Cold Spring Harbor Protocols. 3. DOI: 10.1101/pdb.prot4979 |
0.304 |
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| 2007 |
Durocher Y, Pham PL, St-Laurent G, Jacob D, Cass B, Chahal P, Lau CJ, Nalbantoglu J, Kamen A. Scalable serum-free production of recombinant adeno-associated virus type 2 by transfection of 293 suspension cells. Journal of Virological Methods. 144: 32-40. PMID 17467815 DOI: 10.1016/J.Jviromet.2007.03.014 |
0.409 |
|
| 2007 |
Segura MM, Garnier A, Durocher Y, Coelho H, Kamen A. Production of lentiviral vectors by large-scale transient transfection of suspension cultures and affinity chromatography purification. Biotechnology and Bioengineering. 98: 789-99. PMID 17461423 DOI: 10.1002/Bit.21467 |
0.349 |
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| 2007 |
Carpentier E, Paris S, Kamen AA, Durocher Y. Limiting factors governing protein expression following polyethylenimine-mediated gene transfer in HEK293-EBNA1 cells. Journal of Biotechnology. 128: 268-80. PMID 17118475 DOI: 10.1016/J.Jbiotec.2006.10.014 |
0.394 |
|
| 2006 |
Pham PL, Kamen A, Durocher Y. Large-scale transfection of mammalian cells for the fast production of recombinant protein. Molecular Biotechnology. 34: 225-37. PMID 17172668 DOI: 10.1385/Mb:34:2:225 |
0.381 |
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| 2006 |
Daviau A, Proulx R, Robitaille K, Di Fruscio M, Tanguay RM, Landry J, Patterson C, Durocher Y, Blouin R. Down-regulation of the mixed-lineage dual leucine zipper-bearing kinase by heat shock protein 70 and its co-chaperone CHIP. The Journal of Biological Chemistry. 281: 31467-77. PMID 16931512 DOI: 10.1074/Jbc.M607612200 |
0.319 |
|
| 2005 |
Shi C, Shin YO, Hanson J, Cass B, Loewen MC, Durocher Y. Purification and characterization of a recombinant G-protein-coupled receptor, Saccharomyces cerevisiae Ste2p, transiently expressed in HEK293 EBNA1 cells. Biochemistry. 44: 15705-14. PMID 16313173 DOI: 10.1021/Bi051292P |
0.398 |
|
| 2005 |
Pham PL, Perret S, Cass B, Carpentier E, St-Laurent G, Bisson L, Kamen A, Durocher Y. Transient gene expression in HEK293 cells: peptone addition posttransfection improves recombinant protein synthesis. Biotechnology and Bioengineering. 90: 332-44. PMID 15803471 DOI: 10.1002/Bit.20428 |
0.417 |
|
| 2005 |
Cass B, Pham PL, Kamen A, Durocher Y. Purification of recombinant proteins from mammalian cell culture using a generic double-affinity chromatography scheme. Protein Expression and Purification. 40: 77-85. PMID 15721774 DOI: 10.1016/J.Pep.2004.10.023 |
0.425 |
|
| 2005 |
Labrecque L, Lamy S, Chapus A, Mihoubi S, Durocher Y, Cass B, Bojanowski MW, Gingras D, Béliveau R. Combined inhibition of PDGF and VEGF receptors by ellagic acid, a dietary-derived phenolic compound. Carcinogenesis. 26: 821-6. PMID 15661805 DOI: 10.1093/Carcin/Bgi024 |
0.326 |
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| 2005 |
Durocher Y, Pham PL, St-Laurent G, Jacob D, Cass B, Nalbantoglu J, Kamen A. 518. Production of Recombinant Type 2 Adeno-Associated Virus in Bioreactors Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.07.058 |
0.368 |
|
| 2004 |
Petrova PS, Raibekas A, Pevsner J, Vigo N, Anafi M, Moore MK, Peaire A, Shridhar V, Smith DI, Kelly J, Durocher Y, Commissiong JW. Discovering novel phenotype-selective neurotrophic factors to treat neurodegenerative diseases. Progress in Brain Research. 146: 168-83. PMID 14699964 DOI: 10.1016/S0079-6123(03)46012-3 |
0.329 |
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| 2003 |
Pham PL, Perret S, Doan HC, Cass B, St-Laurent G, Kamen A, Durocher Y. Large-scale transient transfection of serum-free suspension-growing HEK293 EBNA1 cells: peptone additives improve cell growth and transfection efficiency. Biotechnology and Bioengineering. 84: 332-42. PMID 12968287 DOI: 10.1002/Bit.10774 |
0.436 |
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| 2003 |
Petrova P, Raibekas A, Pevsner J, Vigo N, Anafi M, Moore MK, Peaire AE, Shridhar V, Smith DI, Kelly J, Durocher Y, Commissiong JW. MANF: a new mesencephalic, astrocyte-derived neurotrophic factor with selectivity for dopaminergic neurons. Journal of Molecular Neuroscience : Mn. 20: 173-88. PMID 12794311 DOI: 10.1385/Jmn:20:2:173 |
0.301 |
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| 2003 |
Elias CB, Carpentier E, Durocher Y, Bisson L, Wagner R, Kamen A. Improving glucose and glutamine metabolism of human HEK 293 and Trichoplusia ni insect cells engineered to express a cytosolic pyruvate carboxylase enzyme. Biotechnology Progress. 19: 90-7. PMID 12573011 DOI: 10.1021/Bp025572X |
0.358 |
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| 2002 |
Durocher Y, Perret S, Kamen A. High-level and high-throughput recombinant protein production by transient transfection of suspension-growing human 293-EBNA1 cells. Nucleic Acids Research. 30: E9. PMID 11788735 DOI: 10.1093/Nar/30.2.E9 |
0.425 |
|
| 2002 |
Hamdan FF, Abramovitz M, Mousa A, Xie J, Durocher Y, Ribeiro P. A novel Schistosoma mansoni G protein-coupled receptor is responsive to histamine. Molecular and Biochemical Parasitology. 119: 75-86. PMID 11755188 DOI: 10.1016/S0166-6851(01)00400-5 |
0.334 |
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| 2001 |
Carpentier E, Lebesgue D, Kamen AA, Hogue M, Bouvier M, Durocher Y. Increased production of active human beta(2)-adrenergic/G(alphas) fusion receptor in Sf-9 cells using nutrient limiting conditions. Protein Expression and Purification. 23: 66-74. PMID 11570847 DOI: 10.1006/Prep.2001.1476 |
0.4 |
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| 2000 |
Durocher Y, Perret S, Thibaudeau E, Gaumond MH, Kamen A, Stocco R, Abramovitz M. A reporter gene assay for high-throughput screening of G-protein-coupled receptors stably or transiently expressed in HEK293 EBNA cells grown in suspension culture. Analytical Biochemistry. 284: 316-26. PMID 10964415 DOI: 10.1006/Abio.2000.4698 |
0.364 |
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| 1998 |
Bhattacharya M, Peri KG, Almazan G, Ribeiro-da-Silva A, Shichi H, Durocher Y, Abramovitz M, Hou X, Varma DR, Chemtob S. Nuclear localization of prostaglandin E2 receptors. Proceedings of the National Academy of Sciences of the United States of America. 95: 15792-7. PMID 9861049 DOI: 10.1073/Pnas.95.26.15792 |
0.346 |
|
| 1992 |
Nguyen LT, Durocher Y, Chapdelaine A, Chevalier S. The major form of protein tyrosine kinase in the dog prostate is expressed by a 50 kDa polypeptide. Febs Letters. 296: 215-8. PMID 1370804 DOI: 10.1016/0014-5793(92)80382-Q |
0.322 |
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