X. William Yang - Publications

University of California, Los Angeles, Los Angeles, CA 
Neurodegenerative Disorder/Basal Ganglia Circuitry

72 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Gu X, Richman J, Langfelder P, Wang N, Zhang S, Bañez-Coronel M, Wang HB, Yang L, Ramanathan L, Deng L, Park CS, Choi CR, Cantle JP, Gao F, Gray M, ... ... Yang XW, et al. Uninterrupted CAG repeat drives striatum-selective transcriptionopathy and nuclear pathogenesis in human Huntingtin BAC mice. Neuron. PMID 35114102 DOI: 10.1016/j.neuron.2022.01.006  0.57
2020 Victor MB, Richner M, Olsen HE, Lee SW, Monteys AM, Ma C, Huh CJ, Zhang B, Davidson BL, Yang XW, Yoo AS. Author Correction: Striatal neurons directly converted from Huntington's disease patient fibroblasts recapitulate age-associated disease phenotypes. Nature Neuroscience. PMID 32879483 DOI: 10.1038/S41593-020-00714-3  0.38
2020 Veldman MB, Park CS, Eyermann CM, Zhang JY, Zuniga-Sanchez E, Hirano AA, Daigle TL, Foster NN, Zhu M, Langfelder P, Lopez IA, Brecha NC, Zipursky SL, Zeng H, Dong HW, ... Yang XW, et al. Brainwide Genetic Sparse Cell Labeling to Illuminate the Morphology of Neurons and Glia with Cre-Dependent MORF Mice. Neuron. PMID 32795398 DOI: 10.1016/J.Neuron.2020.07.019  0.445
2020 Lee CYD, Yang XW. Huntington's Disease: Genome-wide Neuroprotection Screening Goes Viral. Neuron. 106: 4-6. PMID 32272066 DOI: 10.1016/J.Neuron.2020.03.020  0.374
2019 Li HL, Li XY, Dong Y, Zhang YB, Cheng HR, Gan SR, Liu ZJ, Ni W, Burgunder JM, Yang XW, Wu ZY. Clinical and Genetic Profiles in Chinese Patients with Huntington's Disease: A Ten-year Multicenter Study in China. Aging and Disease. 10: 1003-1011. PMID 31595198 DOI: 10.14336/Ad.2018.0911  0.306
2019 Tian X, Richard A, El-Saadi MW, Bhandari A, Latimer B, Van Savage I, Holmes K, Klein RL, Dwyer D, Goeders NE, Yang XW, Lu XH. Dosage sensitivity intolerance of VIPR2 microduplication is disease causative to manifest schizophrenia-like phenotypes in a novel BAC transgenic mouse model. Molecular Psychiatry. PMID 31444475 DOI: 10.1038/S41380-019-0492-3  0.725
2019 Li R, Zhu M, Li J, Bienkowski MS, Foster NN, Xu H, Ard T, Bowman I, Zhou C, Veldman MB, Yang XW, Hintiryan H, Zhang J, Dong HW. Precise segmentation of densely interweaving neuron clusters using G-Cut. Nature Communications. 10: 1549. PMID 30948706 DOI: 10.1038/S41467-019-09515-0  0.353
2019 Wang N, Yang XW. Huntington Disease's Glial Progenitor Cells Hit the Pause Button in the Mouse Brain. Cell Stem Cell. 24: 3-4. PMID 30609397 DOI: 10.1016/J.Stem.2018.12.004  0.331
2018 Lee CYD, Daggett A, Gu X, Jiang LL, Langfelder P, Li X, Wang N, Zhao Y, Park CS, Cooper Y, Ferando I, Mody I, Coppola G, Xu H, Yang XW. Elevated TREM2 Gene Dosage Reprograms Microglia Responsivity and Ameliorates Pathological Phenotypes in Alzheimer's Disease Models. Neuron. 97: 1032-1048.e5. PMID 29518357 DOI: 10.1016/J.Neuron.2018.02.002  0.452
2018 Victor MB, Richner M, Olsen HE, Lee SW, Monteys AM, Ma C, Huh CJ, Zhang B, Davidson BL, Yang XW, Yoo AS. Striatal neurons directly converted from Huntington's disease patient fibroblasts recapitulate age-associated disease phenotypes. Nature Neuroscience. PMID 29403030 DOI: 10.1038/S41593-018-0075-7  0.457
2018 Langfelder P, Gao F, Wang N, Howland D, Kwak S, Vogt TF, Aaronson JS, Rosinski J, Coppola G, Horvath S, Yang XW. MicroRNA signatures of endogenous Huntingtin CAG repeat expansion in mice. Plos One. 13: e0190550. PMID 29324753 DOI: 10.1371/Journal.Pone.0190550  0.388
2017 Veldman MB, Yang XW. Molecular insights into cortico-striatal miscommunications in Huntington's disease. Current Opinion in Neurobiology. 48: 79-89. PMID 29125980 DOI: 10.1016/J.Conb.2017.10.019  0.451
2017 Veldman MB, Yang XW. Huntington's Disease: Nuclear Gatekeepers Under Attack. Neuron. 94: 1-4. PMID 28384467 DOI: 10.1016/J.Neuron.2017.03.032  0.347
2017 Lu XH, Yang XW. Genetically-directed Sparse Neuronal Labeling in BAC Transgenic Mice through Mononucleotide Repeat Frameshift. Scientific Reports. 7: 43915. PMID 28272512 DOI: 10.1038/Srep43915  0.751
2016 Yang XW. Life and death rest on a bivalent chromatin state. Nature Neuroscience. 19: 1271-1273. PMID 27669984 DOI: 10.1038/Nn.4396  0.416
2016 Xu J, Bernstein AM, Wong A, Lu XH, Khoja S, Yang XW, Davies DL, Micevych P, Sofroniew MV, Khakh BS. P2X4 Receptor Reporter Mice: Sparse Brain Expression and Feeding-Related Presynaptic Facilitation in the Arcuate Nucleus. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 8902-20. PMID 27559172 DOI: 10.1523/Jneurosci.1496-16.2016  0.732
2016 Kratter IH, Zahed H, Lau A, Tsvetkov AS, Daub AC, Weiberth KF, Gu X, Saudou F, Humbert S, Yang XW, Osmand A, Steffan JS, Masliah E, Finkbeiner S. Serine 421 regulates mutant huntingtin toxicity and clearance in mice. The Journal of Clinical Investigation. PMID 27525439 DOI: 10.1172/Jci80339  0.462
2016 Hintiryan H, Foster NN, Bowman I, Bay M, Song MY, Gou L, Yamashita S, Bienkowski MS, Zingg B, Zhu M, Yang XW, Shih JC, Toga AW, Dong HW. The mouse cortico-striatal projectome. Nature Neuroscience. PMID 27322419 DOI: 10.1038/Nn.4332  0.315
2016 Chandra A, Sharma A, Calingasan NY, White JM, Shurubor Y, Yang XW, Beal MF, Johri A. Enhanced Mitochondrial Biogenesis Ameliorates Disease Phenotype in a Full-Length Mouse Model of Huntington's Disease. Human Molecular Genetics. PMID 27008868 DOI: 10.1093/Hmg/Ddw095  0.461
2016 Langfelder P, Cantle JP, Chatzopoulou D, Wang N, Gao F, Al-Ramahi I, Lu XH, Ramos EM, El-Zein K, Zhao Y, Deverasetty S, Tebbe A, Schaab C, Lavery DJ, Howland D, ... ... Yang XW, et al. Integrated genomics and proteomics define huntingtin CAG length-dependent networks in mice. Nature Neuroscience. PMID 26900923 DOI: 10.1038/Nn.4256  0.726
2015 Veldman MB, Rios-Galdamez Y, Lu XH, Gu X, Qin W, Li S, Yang XW, Lin S. The N17 domain mitigates nuclear toxicity in a novel zebrafish Huntington's disease model. Molecular Neurodegeneration. 10: 67. PMID 26645399 DOI: 10.1186/S13024-015-0063-2  0.72
2015 Park CS, Yang XW. Probing the stress and depression circuits with a disease gene. Elife. 4. PMID 26371507 DOI: 10.7554/Elife.10829  0.325
2015 Estrada-Sánchez AM, Burroughs CL, Cavaliere S, Barton SJ, Chen S, Yang XW, Rebec GV. Cortical efferents lacking mutant huntingtin improve striatal neuronal activity and behavior in a conditional mouse model of Huntington's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 4440-51. PMID 25762686 DOI: 10.1523/JNEUROSCI.2812-14.2015  0.419
2015 Gu X, Cantle JP, Greiner ER, Lee CY, Barth AM, Gao F, Park CS, Zhang Z, Sandoval-Miller S, Zhang RL, Diamond M, Mody I, Coppola G, Yang XW. N17 Modifies mutant Huntingtin nuclear pathogenesis and severity of disease in HD BAC transgenic mice. Neuron. 85: 726-41. PMID 25661181 DOI: 10.1016/J.Neuron.2015.01.008  0.473
2015 Peñagarikano O, Lázaro MT, Lu XH, Gordon A, Dong H, Lam HA, Peles E, Maidment NT, Murphy NP, Yang XW, Golshani P, Geschwind DH. Exogenous and evoked oxytocin restores social behavior in the Cntnap2 mouse model of autism. Science Translational Medicine. 7: 271ra8. PMID 25609168 DOI: 10.1126/Scitranslmed.3010257  0.719
2014 Lu XH, Mattis VB, Wang N, Al-Ramahi I, van den Berg N, Fratantoni SA, Waldvogel H, Greiner E, Osmand A, Elzein K, Xiao J, Dijkstra S, de Pril R, Vinters HV, Faull R, ... ... Yang XW, et al. Targeting ATM ameliorates mutant Huntingtin toxicity in cell and animal models of Huntington's disease. Science Translational Medicine. 6: 268ra178. PMID 25540325 DOI: 10.1126/Scitranslmed.3010523  0.735
2014 Wang N, Gray M, Lu XH, Cantle JP, Holley SM, Greiner E, Gu X, Shirasaki D, Cepeda C, Li Y, Dong H, Levine MS, Yang XW. Neuronal targets for reducing mutant huntingtin expression to ameliorate disease in a mouse model of Huntington's disease. Nature Medicine. 20: 536-41. PMID 24784230 DOI: 10.1038/Nm.3514  0.789
2014 Haustein MD, Kracun S, Lu XH, Shih T, Jackson-Weaver O, Tong X, Xu J, Yang XW, O'Dell TJ, Marvin JS, Ellisman MH, Bushong EA, Looger LL, Khakh BS. Conditions and constraints for astrocyte calcium signaling in the hippocampal mossy fiber pathway. Neuron. 82: 413-29. PMID 24742463 DOI: 10.1016/J.Neuron.2014.02.041  0.644
2014 Cui Y, Ostlund SB, James AS, Park CS, Ge W, Roberts KW, Mittal N, Murphy NP, Cepeda C, Kieffer BL, Levine MS, Jentsch JD, Walwyn WM, Sun YE, Evans CJ, ... ... Yang XW, et al. Targeted expression of μ-opioid receptors in a subset of striatal direct-pathway neurons restores opiate reward. Nature Neuroscience. 17: 254-61. PMID 24413699 DOI: 10.1038/Nn.3622  0.786
2013 Wang N, Lu XH, Sandoval SV, Yang XW. An independent study of the preclinical efficacy of C2-8 in the R6/2 transgenic mouse model of Huntington's disease. Journal of Huntington's Disease. 2: 443-51. PMID 25062731 DOI: 10.3233/Jhd-130074  0.706
2013 Daggett A, Yang XW. Huntington's disease: easing the NMDAR traffic jam. Nature Medicine. 19: 971-3. PMID 23921742 DOI: 10.1038/Nm.3283  0.378
2013 Lee CY, Cantle JP, Yang XW. Genetic manipulations of mutant huntingtin in mice: new insights into Huntington's disease pathogenesis. The Febs Journal. 280: 4382-94. PMID 23829302 DOI: 10.1111/Febs.12418  0.492
2013 Yue Z, Yang XW. Dangerous duet: LRRK2 and α-synuclein jam at CMA. Nature Neuroscience. 16: 375-7. PMID 23528933 DOI: 10.1038/Nn.3361  0.307
2013 Southwell AL, Warby SC, Carroll JB, Doty CN, Skotte NH, Zhang W, Villanueva EB, Kovalik V, Xie Y, Pouladi MA, Collins JA, Yang XW, Franciosi S, Hayden MR. A fully humanized transgenic mouse model of Huntington disease. Human Molecular Genetics. 22: 18-34. PMID 23001568 DOI: 10.1093/Hmg/Dds397  0.442
2012 Yu-Taeger L, Petrasch-Parwez E, Osmand AP, Redensek A, Metzger S, Clemens LE, Park L, Howland D, Calaminus C, Gu X, Pichler B, Yang XW, Riess O, Nguyen HP. A novel BACHD transgenic rat exhibits characteristic neuropathological features of Huntington disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 15426-38. PMID 23115180 DOI: 10.1523/Jneurosci.1148-12.2012  0.428
2012 Shirasaki DI, Greiner ER, Al-Ramahi I, Gray M, Boontheung P, Geschwind DH, Botas J, Coppola G, Horvath S, Loo JA, Yang XW. Network organization of the huntingtin proteomic interactome in mammalian brain. Neuron. 75: 41-57. PMID 22794259 DOI: 10.1016/J.Neuron.2012.05.024  0.492
2012 Lu XH, Yang XW. "Huntingtin holiday": progress toward an antisense therapy for Huntington's disease. Neuron. 74: 964-6. PMID 22726826 DOI: 10.1016/J.Neuron.2012.06.001  0.701
2012 Gafni J, Papanikolaou T, Degiacomo F, Holcomb J, Chen S, Menalled L, Kudwa A, Fitzpatrick J, Miller S, Ramboz S, Tuunanen PI, Lehtimäki KK, Yang XW, Park L, Kwak S, et al. Caspase-6 activity in a BACHD mouse modulates steady-state levels of mutant huntingtin protein but is not necessary for production of a 586 amino acid proteolytic fragment. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 7454-65. PMID 22649225 DOI: 10.1523/Jneurosci.6379-11.2012  0.401
2012 Jiang M, Wang J, Fu J, Du L, Jeong H, West T, Xiang L, Peng Q, Hou Z, Cai H, Seredenina T, Arbez N, Zhu S, Sommers K, Qian J, ... ... Yang XW, et al. Neuroprotective role of Sirt1 in mammalian models of Huntington's disease through activation of multiple Sirt1 targets. Nature Medicine. 18: 153-8. PMID 22179319 DOI: 10.1038/Nm.2558  0.475
2012 Miller J, Arrasate M, Brooks E, Libeu CP, Legleiter J, Hatters D, Curtis J, Cheung K, Krishnan P, Mitra S, Widjaja K, Shaby BA, Lotz GP, Newhouse Y, Mitchell EJ, ... ... Yang XW, et al. Erratum: Corrigendum: Identifying polyglutamine protein species in situ that best predict neurodegeneration Nature Chemical Biology. 8: 318-318. DOI: 10.1038/Nchembio0312-318A  0.429
2012 Cantle JP, Lu XH, Gu X, Yang XW. Cellular and molecular mechanisms implicated in pathogenesis of selective neurodegeneration in Huntington's disease Frontiers in Biology. 7: 459-476. DOI: 10.1007/S11515-012-1246-7  0.736
2011 Miller J, Arrasate M, Brooks E, Libeu CP, Legleiter J, Hatters D, Curtis J, Cheung K, Krishnan P, Mitra S, Widjaja K, Shaby BA, Lotz GP, Newhouse Y, Mitchell EJ, ... ... Yang XW, et al. Identifying polyglutamine protein species in situ that best predict neurodegeneration. Nature Chemical Biology. 7: 925-34. PMID 22037470 DOI: 10.1038/Nchembio.694  0.504
2011 Greiner ER, Yang XW. Huntington's disease: flipping a switch on huntingtin. Nature Chemical Biology. 7: 412-4. PMID 21685885 DOI: 10.1038/Nchembio.604  0.353
2011 Tao J, Wu H, Lin Q, Wei W, Lu XH, Cantle JP, Ao Y, Olsen RW, Yang XW, Mody I, Sofroniew MV, Sun YE. Deletion of astroglial Dicer causes non-cell-autonomous neuronal dysfunction and degeneration. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 8306-19. PMID 21632951 DOI: 10.1523/Jneurosci.0567-11.2011  0.716
2011 Wilburn B, Rudnicki DD, Zhao J, Weitz TM, Cheng Y, Gu X, Greiner E, Park CS, Wang N, Sopher BL, La Spada AR, Osmand A, Margolis RL, Sun YE, Yang XW. An antisense CAG repeat transcript at JPH3 locus mediates expanded polyglutamine protein toxicity in Huntington's disease-like 2 mice. Neuron. 70: 427-40. PMID 21555070 DOI: 10.1016/J.Neuron.2011.03.021  0.757
2011 Yang XW, Lu XH. Molecular and cellular basis of obsessive-compulsive disorder-like behaviors: emerging view from mouse models. Current Opinion in Neurology. 24: 114-8. PMID 21386675 DOI: 10.1097/Wco.0B013E32834451Fb  0.699
2011 André VM, Cepeda C, Fisher YE, Huynh M, Bardakjian N, Singh S, Yang XW, Levine MS. Differential electrophysiological changes in striatal output neurons in Huntington's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 1170-82. PMID 21273402 DOI: 10.1523/Jneurosci.3539-10.2011  0.42
2011 Yang Z, Jiang H, Chaichanasakul T, Gong S, Yang XW, Heintz N, Lin S. Corrigendum to " Modified bacterial artificial chromosomes for zebrafish transgenesis" Methods 39 (2006) 183-188 Methods. 53: 327. DOI: 10.1016/J.Ymeth.2010.11.001  0.397
2010 Graham RK, Deng Y, Carroll J, Vaid K, Cowan C, Pouladi MA, Metzler M, Bissada N, Wang L, Faull RL, Gray M, Yang XW, Raymond LA, Hayden MR. Cleavage at the 586 amino acid caspase-6 site in mutant huntingtin influences caspase-6 activation in vivo. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 15019-29. PMID 21068307 DOI: 10.1523/Jneurosci.2071-10.2010  0.548
2010 Pouladi MA, Xie Y, Skotte NH, Ehrnhoefer DE, Graham RK, Kim JE, Bissada N, Yang XW, Paganetti P, Friedlander RM, Leavitt BR, Hayden MR. Full-length huntingtin levels modulate body weight by influencing insulin-like growth factor 1 expression. Human Molecular Genetics. 19: 1528-38. PMID 20097678 DOI: 10.1093/Hmg/Ddq026  0.365
2010 Karsten SL, Parfenova L, Lau K, Vi N, Hui M, Gray M, Yang XW, Hui K, Kudo LC. P1-369: Overexpression of puromycin sensitive aminopeptidase (PSA/NPEPPS) reduces soluble tau and delays development of neuropathology in PSA/TAU-P301L double transgenic mice Alzheimer's & Dementia. 6: S280-S280. DOI: 10.1016/J.Jalz.2010.05.923  0.485
2009 Gu X, Greiner ER, Mishra R, Kodali R, Osmand A, Finkbeiner S, Steffan JS, Thompson LM, Wetzel R, Yang XW. Serines 13 and 16 are critical determinants of full-length human mutant huntingtin induced disease pathogenesis in HD mice. Neuron. 64: 828-40. PMID 20064390 DOI: 10.1016/J.Neuron.2009.11.020  0.48
2009 Menalled L, El-Khodor BF, Patry M, Suárez-Fariñas M, Orenstein SJ, Zahasky B, Leahy C, Wheeler V, Yang XW, MacDonald M, Morton AJ, Bates G, Leeds J, Park L, Howland D, et al. Systematic behavioral evaluation of Huntington's disease transgenic and knock-in mouse models. Neurobiology of Disease. 35: 319-36. PMID 19464370 DOI: 10.1016/J.Nbd.2009.05.007  0.404
2009 Hutnick LK, Golshani P, Namihira M, Xue Z, Matynia A, Yang XW, Silva AJ, Schweizer FE, Fan G. DNA hypomethylation restricted to the murine forebrain induces cortical degeneration and impairs postnatal neuronal maturation. Human Molecular Genetics. 18: 2875-88. PMID 19433415 DOI: 10.1093/Hmg/Ddp222  0.624
2009 Lu XH, Fleming SM, Meurers B, Ackerson LC, Mortazavi F, Lo V, Hernandez D, Sulzer D, Jackson GR, Maidment NT, Chesselet MF, Yang XW. Bacterial artificial chromosome transgenic mice expressing a truncated mutant parkin exhibit age-dependent hypokinetic motor deficits, dopaminergic neuron degeneration, and accumulation of proteinase K-resistant alpha-synuclein. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 1962-76. PMID 19228951 DOI: 10.1523/Jneurosci.5351-08.2009  0.742
2009 Kudo LC, Vi N, Lau K, Parfenova L, Hui M, Gray M, Yang X, Wiedau-Pazos M, Hui K, Karsten S. P3-205: Effect of puromycin sensitive aminopeptidase overexpression on TAU protein metabolism in vivo Alzheimer's & Dementia. 5: P403-P403. DOI: 10.1016/J.Jalz.2009.04.978  0.451
2008 Spampanato J, Gu X, Yang XW, Mody I. Progressive synaptic pathology of motor cortical neurons in a BAC transgenic mouse model of Huntington's disease. Neuroscience. 157: 606-20. PMID 18854207 DOI: 10.1016/J.Neuroscience.2008.09.020  0.342
2008 Gray M, Shirasaki DI, Cepeda C, André VM, Wilburn B, Lu XH, Tao J, Yamazaki I, Li SH, Sun YE, Li XJ, Levine MS, Yang XW. Full-length human mutant huntingtin with a stable polyglutamine repeat can elicit progressive and selective neuropathogenesis in BACHD mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 6182-95. PMID 18550760 DOI: 10.1523/Jneurosci.0857-08.2008  0.788
2008 Lobo MK, Yeh C, Yang XW. Pivotal role of early B-cell factor 1 in development of striatonigral medium spiny neurons in the matrix compartment. Journal of Neuroscience Research. 86: 2134-46. PMID 18338816 DOI: 10.1002/Jnr.21666  0.677
2008 Yang XW, Lu XH. The Bac Transgenic Approach to Study Parkinson's Disease in Mice Parkinson's Disease. 247-268. DOI: 10.1016/B978-0-12-374028-1.00019-1  0.31
2007 Lobo MK, Cui Y, Ostlund SB, Balleine BW, Yang XW. Genetic control of instrumental conditioning by striatopallidal neuron-specific S1P receptor Gpr6. Nature Neuroscience. 10: 1395-7. PMID 17934457 DOI: 10.1038/Nn1987  0.775
2007 Gu X, André VM, Cepeda C, Li SH, Li XJ, Levine MS, Yang XW. Pathological cell-cell interactions are necessary for striatal pathogenesis in a conditional mouse model of Huntington's disease. Molecular Neurodegeneration. 2: 8. PMID 17470275 DOI: 10.1186/1750-1326-2-8  0.475
2006 Yang Z, Jiang H, Chaichanasakul T, Chachainasakul T, Gong S, Yang XW, Heintz N, Lin S. Modified bacterial artificial chromosomes for zebrafish transgenesis. Methods (San Diego, Calif.). 39: 183-8. PMID 16828309 DOI: 10.1016/j.ymeth.2006.04.011  0.473
2006 Lobo MK, Karsten SL, Gray M, Geschwind DH, Yang XW. FACS-array profiling of striatal projection neuron subtypes in juvenile and adult mouse brains. Nature Neuroscience. 9: 443-52. PMID 16491081 DOI: 10.1038/Nn1654  0.709
2005 Gong S, Yang XW. Modification of bacterial artificial chromosomes (BACs) and preparation of intact BAC DNA for generation of transgenic mice. Current Protocols in Neuroscience / Editorial Board, Jacqueline N. Crawley ... [Et Al.]. Unit 5.21. PMID 18428623 DOI: 10.1002/0471142301.Ns0521S31  0.384
2005 Yang XW, Gong S. An overview on the generation of BAC transgenic mice for neuroscience research. Current Protocols in Neuroscience / Editorial Board, Jacqueline N. Crawley ... [Et Al.]. Unit 5.20. PMID 18428622 DOI: 10.1002/0471142301.Ns0520S31  0.453
2005 Gu X, Li C, Wei W, Lo V, Gong S, Li SH, Iwasato T, Itohara S, Li XJ, Mody I, Heintz N, Yang XW. Pathological cell-cell interactions elicited by a neuropathogenic form of mutant Huntingtin contribute to cortical pathogenesis in HD mice. Neuron. 46: 433-44. PMID 15882643 DOI: 10.1016/J.Neuron.2005.03.025  0.642
2002 Gong S, Yang XW, Li C, Heintz N. Highly efficient modification of bacterial artificial chromosomes (BACs) using novel shuttle vectors containing the R6Kgamma origin of replication. Genome Research. 12: 1992-8. PMID 12466304 DOI: 10.1101/Gr.476202  0.464
2001 Misulovin Z, Yang XW, Yu W, Heintz N, Meffre E. A rapid method for targeted modification and screening of recombinant bacterial artificial chromosome. Journal of Immunological Methods. 257: 99-105. PMID 11687243 DOI: 10.1016/S0022-1759(01)00452-5  0.45
1999 Yang XW, Wynder C, Doughty ML, Heintz N. BAC-mediated gene-dosage analysis reveals a role for Zipro1 (Ru49/Zfp38) in progenitor cell proliferation in cerebellum and skin. Nature Genetics. 22: 327-35. PMID 10431235 DOI: 10.1038/11896  0.537
1997 Yang XW, Model P, Heintz N. Homologous recombination based modification in Escherichia coli and germline transmission in transgenic mice of a bacterial artificial chromosome. Nature Biotechnology. 15: 859-65. PMID 9306400 DOI: 10.1038/Nbt0997-859  0.52
1996 Yang XW, Zhong R, Heintz N. Granule cell specification in the developing mouse brain as defined by expression of the zinc finger transcription factor RU49. Development (Cambridge, England). 122: 555-66. PMID 8625807  0.535
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