| Year |
Citation |
Score |
| 2004 |
Kamchonwongpaisan S, Quarrell R, Charoensetakul N, Ponsinet R, Vilaivan T, Vanichtanankul J, Tarnchompoo B, Sirawaraporn W, Lowe G, Yuthavong Y. Inhibitors of multiple mutants of Plasmodium falciparum dihydrofolate reductase and their antimalarial activities. Journal of Medicinal Chemistry. 47: 673-80. PMID 14736247 DOI: 10.1021/Jm030165T |
0.654 |
|
| 2003 |
Vilaivan T, Suparpprom C, Duanglaor P, Harnyuttanakorn P, Lowe G. Synthesis and nucleic acid binding studies of novel pyrrolidinyl PNA carrying an N-amino-N-methylglycine spacer Tetrahedron Letters. 44: 1663-1666. DOI: 10.1016/S0040-4039(03)00033-9 |
0.573 |
|
| 2002 |
Vilaivan T, Lowe G. A novel pyrrolidinyl PNA showing high sequence specificity and preferential binding to DNA over RNA. Journal of the American Chemical Society. 124: 9326-7. PMID 12166999 DOI: 10.1021/Ja012543U |
0.558 |
|
| 2001 |
Becker K, Herold-Mende C, Park JJ, Lowe G, Schirmer RH. Human thioredoxin reductase is efficiently inhibited by (2,2':6',2' '-terpyridine)platinum(II) complexes. Possible implications for a novel antitumor strategy. Journal of Medicinal Chemistry. 44: 2784-92. PMID 11495589 DOI: 10.1021/Jm001014I |
0.3 |
|
| 2001 |
Vilaivan T, Suparpprom C, Harnyuttanakorn P, Lowe G. Synthesis and properties of novel pyrrolidinyl PNA carrying β-amino acid spacers Tetrahedron Letters. 42: 5533-5536. DOI: 10.1016/S0040-4039(01)01020-6 |
0.578 |
|
| 2000 |
Vilaivan T, Khongdeesameor C, Harnyuttanakorn P, Westwell MS, Lowe G. Synthesis and properties of chiral peptide nucleic acids with a N-aminoethyl-D-proline backbone. Bioorganic & Medicinal Chemistry Letters. 10: 2541-5. PMID 11086725 DOI: 10.1016/S0960-894X(00)00507-2 |
0.583 |
|
| 2000 |
Yuthavong Y, Vilaivan T, Chareonsethakul N, Kamchonwongpaisan S, Sirawaraporn W, Quarrell R, Lowe G. Development of a lead inhibitor for the A16V+S108T mutant of dihydrofolate reductase from the cycloguanil-resistant strain (T9/94) of Plasmodium falciparum. Journal of Medicinal Chemistry. 43: 2738-44. PMID 10893311 DOI: 10.1021/Jm0009181 |
0.641 |
|
| 2000 |
Rastelli G, Sirawaraporn W, Sompornpisut P, Vilaivan T, Kamchonwongpaisan S, Quarrell R, Lowe G, Thebtaranonth Y, Yuthavong Y. Interaction of pyrimethamine, cycloguanil, WR99210 and their analogues with Plasmodium falciparum dihydrofolate reductase: structural basis of antifolate resistance. Bioorganic & Medicinal Chemistry. 8: 1117-28. PMID 10882022 DOI: 10.1016/S0968-0896(00)00022-5 |
0.656 |
|
| 1999 |
Lowe G, Droz AS, Vilaivan T, Weaver GW, Park JJ, Pratt JM, Tweedale L, Kelland LR. Cytotoxicity of 2,2':6',2-terpyridineplatinum(II) complexes against human ovarian carcinoma Journal of Medicinal Chemistry. 42: 3167-3174. PMID 10447962 DOI: 10.1021/Jm991053Y |
0.519 |
|
| 1999 |
Lowe G, Droz AS, Vilaivan T, Weaver GW, Tweedale L, Pratt JM, Rock P, Yardley V, Croft SL. Cytotoxicity of (2,2':6',2-terpyridine)platinum(II) complexes to Leishmania donovani, Trypanosoma cruzi, and Trypanosoma brucei Journal of Medicinal Chemistry. 42: 999-1006. PMID 10090783 DOI: 10.1021/Jm981074C |
0.537 |
|
| 1998 |
Millington CR, Quarrell R, Lowe G. Aryl hydrazides as linkers for solid phase synthesis which are cleavable under mild oxidative conditions Tetrahedron Letters. 39: 7201-7204. DOI: 10.1016/S0040-4039(98)01543-3 |
0.318 |
|
| 1997 |
Lowe G, Vilaivan T. Solid-phase synthesis of novel peptide nucleic acids Journal of the Chemical Society - Perkin Transactions 1. 555-560. DOI: 10.1039/A603701A |
0.575 |
|
| 1997 |
Lowe G, Vilaivan T. Dipeptides bearing nucleobases for the synthesis of novel peptide nucleic acids Journal of the Chemical Society - Perkin Transactions 1. 547-554. DOI: 10.1039/A603696A |
0.566 |
|
| 1997 |
Lowe G, Vilaivan T, Westwell MS. Hybridization studies with chiral peptide nucleic acids Bioorganic Chemistry. 25: 321-329. DOI: 10.1006/Bioo.1997.1078 |
0.577 |
|
| 1996 |
Lowe G, McCloskey JA, Ni J, Vilaivan T. A mass spectrometric investigation of the reaction between 4,4'-vinylenedipyridine bis[2,2':6',2"-terpyridine platinum(II)] and the self-complementary oligonucleotide d(CpGpTpApCpG). Bioorganic & Medicinal Chemistry. 4: 1007-13. PMID 8831971 DOI: 10.1016/0968-0896(96)00095-8 |
0.529 |
|
| 1995 |
Chesshyre JA, Kraunsoe JAE, Lowe G. Production of bovine-pancreatic-trypsin-inhibitor homologues in Escherichia coli and their characterization Biotechnology and Applied Biochemistry. 22: 269-280. DOI: 10.1111/J.1470-8744.1995.Tb00351.X |
0.324 |
|
| 1994 |
Lowe G, Quarrell R. Screening Peptide Bead Libraries for Enzyme Inhibitors Methods. 6: 411-416. DOI: 10.1006/Meth.1994.1043 |
0.3 |
|
| 1992 |
Lumb KJ, Aplin RT, Radford SE, Archer DB, Jeenes DJ, Lambert N, MacKenzie DA, Dobson CM, Lowe G. A study of D52S hen lysozyme-GlcNAc oligosaccharide complexes by NMR spectroscopy and electrospray mass spectrometry. Febs Letters. 296: 153-7. PMID 1733771 DOI: 10.1016/0014-5793(92)80368-Q |
0.316 |
|
| 1992 |
Christina L, Lowe G. The mechanism and stereochemical course of sulfuryl transfer catalyzed by the aryl sulfotransferase from Eubacterium A-44 Bioorganic Chemistry. 20: 181-188. DOI: 10.1016/0045-2068(92)90011-Q |
0.325 |
|
| 1991 |
Lowe G. Mechanisms of Sulphate Activation and Transfer Philosophical Transactions of the Royal Society B. 332: 141-148. DOI: 10.1098/Rstb.1991.0042 |
0.355 |
|
| 1991 |
Lowe G. THE STEREOCHEMICAL COURSE OF SULPHURYL TRANSFER REACTIONS Phosphorus, Sulfur, and Silicon and the Related Elements. 59: 63-77. DOI: 10.1080/10426509108045701 |
0.315 |
|
| 1991 |
Lowe G. Stereochemical Analysis of the Enzymic Synthesis and Hydrolysis of Ap4A Nucleosides and Nucleotides. 10: 181-193. DOI: 10.1080/07328319108046445 |
0.328 |
|
| 1991 |
Chai CLL, Hepburn TW, Lowe G. Synthesis of phenyl [(R)16O,17O,18O]sulphate and the stereochemical course of a sulphuryl transfer reaction Journal of the Chemical Society, Chemical Communications. 1403-1405. DOI: 10.1039/C39910001403 |
0.304 |
|
| 1990 |
Hepburn TW, Lowe G. Synthesis of [18O]thionyl chloride Journal of Labelled Compounds and Radiopharmaceuticals. 28: 617-620. DOI: 10.1002/Jlcr.2580280512 |
0.315 |
|
| 1989 |
Lowe G, Potter BVL. Synthesis of inorganic P1-[(S)-16O, 17O, 18O]pyrophosphate Journal of Labelled Compounds and Radiopharmaceuticals. 27: 63-73. DOI: 10.1002/Jlcr.2580270110 |
0.307 |
|
| 1988 |
Bethell RC, Lowe G. The stereochemical course of d‐glyceraldehyde‐induced ATPase activity of glycerokinase from Escherichia coli Febs Journal. 174: 387-389. PMID 2838275 DOI: 10.1111/J.1432-1033.1988.Tb14109.X |
0.341 |
|
| 1988 |
Bethell RC, Lowe G, Hosseini MW, Lehn J. Mechanisms of the ATPase-like activity of the macrocyclic polyamine receptor molecule [24]N6O2 Bioorganic Chemistry. 16: 418-428. DOI: 10.1016/0045-2068(88)90027-2 |
0.349 |
|
| 1988 |
Lowe G, Parratt MJ. A stereochemical analysis of chiral [16O, 17O, 18O]sulfate monoesters using Fourier transform infrared spectroscopy Bioorganic Chemistry. 16: 283-297. DOI: 10.1016/0045-2068(88)90016-8 |
0.308 |
|
| 1987 |
Arnold JRP, Bethell RC, Lowe G. Chiral inorganic [16O, 17O, 18O]thiophosphate: Synthesis and stereochemical analysis Bioorganic Chemistry. 15: 250-261. DOI: 10.1016/0045-2068(87)90023-X |
0.322 |
|
| 1987 |
Bethell RC, Lowe G. Synthesis of S-benzyl-[18O3]phosphorothioate and adenosine 5prime;-[18O3]phosphate Journal of Labelled Compounds and Radiopharmaceuticals. 24: 239-246. DOI: 10.1002/Jlcr.2580240303 |
0.323 |
|
| 1986 |
LOWE G, PARRATT MJ. Synthesis and Stereochemical Analysis of Chiral [16O,17O,18O]Sulfate Esters Annals of the New York Academy of Sciences. 471: 310-313. DOI: 10.1111/J.1749-6632.1986.Tb48051.X |
0.307 |
|
| 1984 |
Lowe G, Tansley G. An investigation of the mechanism of activation of tryptophan by tryptophanyl‐tRNA synthetase from beef pancreas Febs Journal. 138: 597-602. PMID 6692836 DOI: 10.1111/J.1432-1033.1984.Tb07956.X |
0.358 |
|
| 1984 |
Lowe G, Tansley G. A stereochemical and positional isotope exchange study of the mechanism of activation of tyrosine by tyrosyl-tRNA synthetase from Bacillus stearothermophilus Tetrahedron. 40: 113-117. DOI: 10.1016/0040-4020(84)85109-1 |
0.353 |
|
| 1983 |
Lowe G, Sproat BS, Tansley G. A stereochemical and positional isotope-exchange study of the mechanism of activation of methionine by methionyl-tRNA synthetase from Escherichia coli. Febs Journal. 130: 341-345. PMID 6337846 DOI: 10.1111/J.1432-1033.1983.Tb07158.X |
0.351 |
|
| 1983 |
Lowe G, Tansley G. The stereochemical course of nucleotidyl transfer catalysed by NAD pyrophosphorylase. Febs Journal. 132: 117-120. PMID 6301818 DOI: 10.1111/J.1432-1033.1983.Tb07334.X |
0.333 |
|
| 1982 |
Pollard-Knight D, Potter BV, Cullis PM, Lowe G, Cornish-Bowden A. The stereochemical course of phosphoryl transfer catalysed by glucokinase. The Biochemical Journal. 201: 421-3. PMID 6896275 DOI: 10.1042/Bj2010421 |
0.524 |
|
| 1982 |
Lowe G, Potter BV. The stereochemical course of phosphoryl transfer catalysed by glucose 6-phosphatase. The Biochemical Journal. 201: 665-8. PMID 6284126 DOI: 10.1042/Bj2010665 |
0.447 |
|
| 1981 |
Lowe G, Potter BV. The stereochemical course of yeast hexokinase-catalysed phosphoryl transfer by using adenosine 5'[gamma(S)-16O,17O,18O]triphosphate as substrate. The Biochemical Journal. 199: 227-33. PMID 7039616 DOI: 10.1042/Bj1990227 |
0.476 |
|
| 1981 |
Lowe G, Potter BV. A stereochemical investigation of phosphoryl transfer catalysed by phosphoglucomutase by the use of alpha-D-glucose 1-[(S)-16O,17O,18O]phosphate. The Biochemical Journal. 199: 693-8. PMID 6462135 DOI: 10.1042/Bj1990693 |
0.466 |
|
| 1981 |
Jarvest RL, Lowe G, Potter BV. The stereochemical course of phosphoryl transfer catalysed by Bacillus stearothermophilus and rabbit skeletal-muscle phosphofructokinase with a chiral [16O,17O,18O]phosphate ester. The Biochemical Journal. 199: 427-32. PMID 6462132 DOI: 10.1042/Bj1990427 |
0.457 |
|
| 1981 |
Rubio V, Britton HG, Grisolia S, Sproat BS, Lowe G. Mechanism of activation of bicarbonate ion by mitochondrial carbamoyl-phosphate synthetase: formation of enzyme-bound adenosine diphosphate from the adenosine triphosphate that yields inorganic phosphate. Biochemistry. 20: 1969-1974. PMID 6261808 DOI: 10.1021/Bi00510A036 |
0.315 |
|
| 1981 |
Lowe G, Cullis PM, Jarvest RL, Potter BV, Sproat BS. Stereochemistry of phosphoryl transfer. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 293: 75-92. PMID 6115426 DOI: 10.1098/Rstb.1981.0062 |
0.527 |
|
| 1980 |
Jones VT, Lowe G, Potter BV. Evidence against a step-wise mechanism for the fumarase-catalysed dehydration of (2S)-malate. European Journal of Biochemistry. 108: 433-7. PMID 7408860 DOI: 10.1111/J.1432-1033.1980.Tb04739.X |
0.427 |
|
| 1980 |
Lowe G, Potter BVL. Synthesis, absolute configuration, and circular dichroism of the enantiomers of fluorosuccinic acid Journal of the Chemical Society-Perkin Transactions 1. 1980: 2029-2032. DOI: 10.1039/P19800002029 |
0.319 |
|
| 1978 |
Clark PI, Lowe G. Conversion of the active-site cysteine residue of papain into a dehydro-serine, a serine and a glycine residue. European Journal of Biochemistry / Febs. 84: 293-9. PMID 25772 DOI: 10.1111/J.1432-1033.1978.Tb12168.X |
0.312 |
|
| 1978 |
Lowe G, Sproat BS. Evidence of a dissociative SN1(P) mechanism of phosphoryl transfer by rabbit muscle pyruvate kinase Journal of the Chemical Society-Perkin Transactions 1. 1622-1630. DOI: 10.1039/P19780001622 |
0.323 |
|
| 1977 |
Bendall MR, Cartwright IL, Clark PI, Lowe G, Nurse D. Inhibition of papain by N-acyl-aminoacetaldehydes and N-acyl-aminopropanones. Evidence for hemithioacetal formation by a cross-saturation technique in nuclear-magnetic resonance spectroscopy. European Journal of Biochemistry / Febs. 79: 201-9. PMID 913417 DOI: 10.1111/J.1432-1033.1977.Tb11798.X |
0.308 |
|
| 1977 |
Lewis DJ, Lowe G. Inhibition of fructose-1,6-biphosphate aldolase from rabbit muscle and Bacillus stearothermophilus European Journal of Biochemistry. 80: 119-133. PMID 562749 DOI: 10.1111/J.1432-1033.1977.Tb11864.X |
0.325 |
|
| 1975 |
Alecio MR, Dann ML, Lowe G. The specificity of the S1' subsite of papain. The Biochemical Journal. 141: 495-501. PMID 4455218 DOI: 10.1042/Bj1410495 |
0.359 |
|
| 1973 |
Lowe G, Yeung HW. Synthesis of a β-lactam related to the cephalosporins Journal of the Chemical Society-Perkin Transactions 1. 5: 2907-2910. DOI: 10.1039/P19730002907 |
0.321 |
|
| 1972 |
Lowe G, Yuthavong Y. pH-dependence and structure-activity relationships in the papain-catalysed hydrolysis of anilides. The Biochemical Journal. 124: 117-22. PMID 5126467 DOI: 10.1042/Bj1240117 |
0.523 |
|
| 1972 |
Lowe G, Yuthavong Y. Kinetic specificity in papain-catalysed hydrolyses. The Biochemical Journal. 124: 107-15. PMID 5126466 DOI: 10.1042/Bj1240107 |
0.588 |
|
| 1972 |
Lowe G. The structure and mechanism of action of papain. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 257: 237-48. PMID 4399048 DOI: 10.1098/Rstb.1970.0023 |
0.301 |
|
| 1966 |
Hodge P, Jones ER, Lowe G. Natural acetylenes. XXII. Trans-Dehydromatricaria ester as a biosynthetic precursor of some fungal polyacetylenes. Journal of the Chemical Society. Perkin Transactions 1. 14: 1216-9. PMID 5949256 |
0.713 |
|
| 1958 |
Lowe G, Torto FG, Weedon BCL. 377. Studies in the polyene series. Part LIII. The synthesis of pseudocumyl analogues of β-ionone and vitamin a acid Journal of the Chemical Society (Resumed). 1855-1861. DOI: 10.1039/JR9580001855 |
0.49 |
|
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