| Year |
Citation |
Score |
| 2019 |
Almeida TMd, Danielli LJ, Apel MA, Cassel E, Vargas RM, Von Poser GL, Müller LG, Rates SM. A valepotriate-enriched fraction from Valeriana glechomifolia Meyer inhibits leukocytes migration and nociception in formalin test in rodents Revista Brasileira De Farmacognosia. 29: 477-482. DOI: 10.1016/J.Bjp.2019.02.004 |
0.381 |
|
| 2016 |
Betti AH, Antonio CB, Pompeu TE, Martins TS, Herzfeldt V, Stolz ED, Fraga CA, Barreiro E, Noël F, Rates SM. LASSBio-1422: a new molecular scaffold with efficacy in animal models of schizophrenia and disorders of attention and cognition. Behavioural Pharmacology. PMID 27755061 DOI: 10.1097/Fbp.0000000000000267 |
0.658 |
|
| 2016 |
Stolz ED, da Costa PF, Medeiros LF, Souza A, Battastini AM, von Poser GL, Bonan C, Torres IL, Rates SM. Uliginosin B, a Possible New Analgesic Drug, Acts by Modulating the Adenosinergic System. Evidence-Based Complementary and Alternative Medicine : Ecam. 2016: 5890590. PMID 27087824 DOI: 10.1155/2016/5890590 |
0.355 |
|
| 2016 |
Bridi H, Ccana-Ccapatinta GV, Stolz ED, Meirelles GC, Bordignon SA, Rates SM, von Poser GL. Dimeric acylphloroglucinols from Hypericum austrobrasiliense exhibiting antinociceptive activity in mice. Phytochemistry. 122: 178-83. PMID 26723883 DOI: 10.1016/J.Phytochem.2015.12.012 |
0.398 |
|
| 2016 |
Antonio CB, Betti AH, Herzfeldt V, Barreiro EJ, Fraga CA, Rates SM. LASSBio-579, a prototype antipsychotic drug, and clozapine are effective in novel object recognition task, a recognition memory model. Behavioural Pharmacology. 27: 339-49. PMID 26513177 DOI: 10.1097/Fbp.0000000000000200 |
0.363 |
|
| 2016 |
Stein AC, Müller LG, Ferreira AG, Braga A, Betti AH, Centurião FB, Scherer EB, Kolling J, von Poser GL, Wyse AT, Rates SM. Uliginosin B, a natural phloroglucinol derivative with antidepressant-like activity, increases Na+,K+-ATPase activity in mice cerebral cortex Revista Brasileira De Farmacognosia. 26: 611-618. DOI: 10.1016/J.Bjp.2016.04.005 |
0.36 |
|
| 2015 |
Müller LG, Borsoi M, Stolz ED, Herzfeldt V, Viana AF, Ravazzolo AP, Rates SM. Diene Valepotriates from Valeriana glechomifolia Prevent Lipopolysaccharide-Induced Sickness and Depressive-Like Behavior in Mice. Evidence-Based Complementary and Alternative Medicine : Ecam. 2015: 145914. PMID 26170871 DOI: 10.1155/2015/145914 |
0.317 |
|
| 2015 |
Valli M, Betti AH, Danuello A, Pivatto M, Centurião F, Antonio CB, Rates SM, Bolzani Vda S. Pyridinic analog of the natural product (-)-spectaline as potential adjuvant for the treatment of central nervous system disorders. Bioorganic & Medicinal Chemistry Letters. 25: 2247-50. PMID 25900218 DOI: 10.1016/J.Bmcl.2015.02.050 |
0.435 |
|
| 2015 |
Müller LG, Stolz ED, Betti AH, Herzfeldt V, Rates SM. Synergistic interaction between diene valepotriates from Valeriana glechomifolia Meyer (Valerianaceae) and classical antidepressants: an isobolographic analysis. The Journal of Pharmacy and Pharmacology. 67: 1008-16. PMID 25880123 DOI: 10.1111/Jphp.12396 |
0.319 |
|
| 2015 |
Müller LG, Salles L, Lins HA, Feijó PR, Cassel E, Vargas R, von Poser GL, Noël F, Quintas LE, Rates SM. Effects of diene valepotriates from valeriana glechomifolia on Na+/K+-ATPase activity in the cortex and hippocampus of mice. Planta Medica. 81: 200-7. PMID 25615276 DOI: 10.1055/S-0034-1396200 |
0.587 |
|
| 2015 |
Borsoi M, Antonio CB, Müller LG, Viana AF, Hertzfeldt V, Lunardi PS, Zanotto C, Nardin P, Ravazzolo AP, Rates SM, Gonçalves CA. Repeated forced swimming impairs prepulse inhibition and alters brain-derived neurotrophic factor and astroglial parameters in rats. Pharmacology, Biochemistry, and Behavior. 128: 50-61. PMID 25444867 DOI: 10.1016/J.Pbb.2014.11.012 |
0.313 |
|
| 2014 |
Borsoi M, Antonio CB, Viana AF, Nardin P, Gonçalves CA, Rates SM. Immobility behavior during the forced swim test correlates with BNDF levels in the frontal cortex, but not with cognitive impairments. Physiology & Behavior. 140: 79-88. PMID 25496978 DOI: 10.1016/J.Physbeh.2014.12.024 |
0.304 |
|
| 2014 |
Ccana-Ccapatinta GV, Stolz ED, da Costa PF, Rates SM, von Poser GL. Acylphloroglucinol derivatives from Hypericum andinum: antidepressant-like activity of andinin A. Journal of Natural Products. 77: 2321-5. PMID 25264905 DOI: 10.1021/Np500426M |
0.372 |
|
| 2014 |
Centurião FB, Braga A, Machado FR, Tagliari B, Müller LG, Kolling J, Poser Gv, Wyse AT, Rates SM. Study of antidepressant-like activity of an enriched phloroglucinol fraction obtained from Hypericum caprifoliatum. Pharmaceutical Biology. 52: 105-10. PMID 24102122 DOI: 10.3109/13880209.2013.816970 |
0.312 |
|
| 2013 |
Pompeu TE, Alves FR, Figueiredo CD, Antonio CB, Herzfeldt V, Moura BC, Rates SM, Barreiro EJ, Fraga CA, Noël F. Synthesis and pharmacological evaluation of new N-phenylpiperazine derivatives designed as homologues of the antipsychotic lead compound LASSBio-579. European Journal of Medicinal Chemistry. 66: 122-34. PMID 23792350 DOI: 10.1016/J.Ejmech.2013.05.027 |
0.627 |
|
| 2013 |
Gomes TF, Pompeu TE, Rodrigues DA, Noël F, Menegatti R, Andrade CH, Sabino JR, Gil ES, Dalla Costa T, Betti AH, Antonio CB, Rates SM, Fraga CA, Barreiro EJ, de Oliveira V. Biotransformation of LASSBio-579 and pharmacological evaluation of p-hydroxylated metabolite a N-phenylpiperazine antipsychotic lead compound. European Journal of Medicinal Chemistry. 62: 214-21. PMID 23353740 DOI: 10.1016/J.Ejmech.2012.08.011 |
0.634 |
|
| 2013 |
Neves G, Antonio CB, Betti AH, Pranke MA, Fraga CA, Barreiro EJ, Noël F, Rates SM. New insights into pharmacological profile of LASSBio-579, a multi-target N-phenylpiperazine derivative active on animal models of schizophrenia. Behavioural Brain Research. 237: 86-95. PMID 23000351 DOI: 10.1016/J.Bbr.2012.09.016 |
0.653 |
|
| 2013 |
Passos JJ, De Sousa FB, Mundim IM, Bonfim RR, Melo R, Viana AF, Stolz ED, Borsoi M, Rates SM, Sinisterra RD. Double continuous injection preparation method of cyclodextrin inclusion compounds by spray drying Chemical Engineering Journal. 228: 345-351. DOI: 10.1016/J.Cej.2013.04.074 |
0.325 |
|
| 2012 |
Passos JJ, De Sousa FB, Mundim IM, Bonfim RR, Melo R, Viana AF, Stolz ED, Borsoi M, Rates SM, Sinisterra RD. In vivo evaluation of the highly soluble oral β-cyclodextrin-Sertraline supramolecular complexes. International Journal of Pharmaceutics. 436: 478-85. PMID 22772486 DOI: 10.1016/J.Ijpharm.2012.06.061 |
0.336 |
|
| 2012 |
Socolsky C, Rates SM, Stein AC, Asakawa Y, Bardón A. Acylphloroglucinols from Elaphoglossum crassipes: antidepressant-like activity of crassipin A. Journal of Natural Products. 75: 1007-17. PMID 22686708 DOI: 10.1021/Np200436H |
0.38 |
|
| 2012 |
Stolz ED, Viana AF, Hasse DR, von Poser GL, do Rego JC, Rates SM. Uliginosin B presents antinociceptive effect mediated by dopaminergic and opioid systems in mice. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 39: 80-7. PMID 22627196 DOI: 10.1016/J.Pnpbp.2012.05.012 |
0.389 |
|
| 2012 |
Betti AH, Stein AC, Dallegrave E, Wouters AT, Watanabe TT, Driemeier D, Buffon A, Rates SM. Acute and repeated-doses (28 days) toxicity study of Hypericum polyanthemum Klotzsch ex Reichardt (Guttiferare) in mice. Food and Chemical Toxicology : An International Journal Published For the British Industrial Biological Research Association. 50: 2349-55. PMID 22525862 DOI: 10.1016/J.Fct.2012.04.012 |
0.387 |
|
| 2012 |
Stein AC, Viana AF, Müller LG, Nunes JM, Stolz ED, Do Rego JC, Costentin J, von Poser GL, Rates SM. Uliginosin B, a phloroglucinol derivative from Hypericum polyanthemum: a promising new molecular pattern for the development of antidepressant drugs. Behavioural Brain Research. 228: 66-73. PMID 22155486 DOI: 10.1016/J.Bbr.2011.11.031 |
0.457 |
|
| 2012 |
Müller LG, Salles LA, Stein AC, Betti AH, Sakamoto S, Cassel E, Vargas RF, von Poser GL, Rates SM. Antidepressant-like effect of Valeriana glechomifolia Meyer (Valerianaceae) in mice. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 36: 101-9. PMID 21889562 DOI: 10.1016/J.Pnpbp.2011.08.015 |
0.464 |
|
| 2011 |
Bettero GM, Salles L, Rosário Figueira RM, Poser Gv, Rates SM, Noël F, Quintas LE, Quintas LE. In vitro effect of valepotriates isolated from Valeriana glechomifolia on rat P-type ATPases. Planta Medica. 77: 1702-6. PMID 21567360 DOI: 10.1055/S-0030-1271084 |
0.591 |
|
| 2011 |
Haas JS, Stolz ED, Betti AH, Stein AC, Schripsema J, Poser GL, Rates SM. The anti-immobility effect of hyperoside on the forced swimming test in rats is mediated by the D2-like receptors activation. Planta Medica. 77: 334-9. PMID 20945276 DOI: 10.1055/S-0030-1250386 |
0.474 |
|
| 2010 |
Pazini F, Menegatti R, Sabino JR, Andrade CH, Neves G, Rates SM, Noël F, Fraga CA, Barreiro EJ, de Oliveira V. Design of new dopamine D2 receptor ligands: biosynthesis and pharmacological evaluation of the hydroxylated metabolite of LASSBio-581. Bioorganic & Medicinal Chemistry Letters. 20: 2888-91. PMID 20363131 DOI: 10.1016/J.Bmcl.2010.03.034 |
0.59 |
|
| 2010 |
Haas JS, Viana AF, Heckler AP, von Poser GL, Rates SM. The antinociceptive effect of a benzopyran (HP1) isolated from Hypericum polyanthemum in mice hot-plate test is blocked by naloxone. Planta Medica. 76: 1419-23. PMID 20309796 DOI: 10.1055/S-0029-1240942 |
0.431 |
|
| 2010 |
Neves G, Menegatti R, Antonio CB, Grazziottin LR, Vieira RO, Rates SM, Noël F, Barreiro EJ, Fraga CA. Searching for multi-target antipsychotics: Discovery of orally active heterocyclic N-phenylpiperazine ligands of D2-like and 5-HT1A receptors. Bioorganic & Medicinal Chemistry. 18: 1925-35. PMID 20153652 DOI: 10.1016/J.Bmc.2010.01.040 |
0.591 |
|
| 2010 |
Boeira JM, Fenner R, Betti AH, Provensi G, Lacerda Lde A, Barbosa PR, González FH, Corrêa AM, Driemeier D, Dall'Alba MP, Pedroso AP, Gosmann G, da Silva J, Rates SM. Toxicity and genotoxicity evaluation of Passiflora alata Curtis (Passifloraceae). Journal of Ethnopharmacology. 128: 526-32. PMID 19799991 DOI: 10.1016/J.Jep.2009.09.037 |
0.41 |
|
| 2008 |
Conrado DJ, Verli H, Neves G, Fraga CA, Barreiro EJ, Rates SM, Dalla Costa T. Pharmacokinetic evaluation of LASSBio-579: an N-phenylpiperazine antipsychotic prototype. The Journal of Pharmacy and Pharmacology. 60: 699-707. PMID 18498705 DOI: 10.1211/Jpp.60.6.0004 |
0.613 |
|
| 2008 |
Viana A, Rates S, Naudin B, Janin F, Costentin J, do Rego JC. Effects of acute or 3-day treatments of Hypericum caprifoliatum Cham. & Schltdt. (Guttiferae) extract or of two established antidepressants on basal and stress-induced increase in serum and brain corticosterone levels. Journal of Psychopharmacology (Oxford, England). 22: 681-90. PMID 18308787 DOI: 10.1177/0269881107082898 |
0.367 |
|
| 2008 |
Neves G, Kliemann M, Betti AH, Conrado DJ, Tasso L, Fraga CA, Barreiro EJ, Teresa Dalla Costa, Rates SM. Serotonergic neurotransmission mediates hypothermia induced by the N-phenylpiperazine antipsychotic prototypes LASSBio-579 and LASSBio-581. Pharmacology, Biochemistry, and Behavior. 89: 23-30. PMID 18082872 DOI: 10.1016/J.Pbb.2007.10.018 |
0.642 |
|
| 2006 |
Viana AF, do Rego JC, Munari L, Dourmap N, Heckler AP, Costa TD, von Poser GL, Costentin J, Rates SM. Hypericum caprifoliatum (Guttiferae) Cham. & Schltdl.: a species native to South Brazil with antidepressant-like activity. Fundamental & Clinical Pharmacology. 20: 507-14. PMID 17109644 DOI: 10.1111/J.1472-8206.2006.00440.X |
0.413 |
|
| 2005 |
Tasso L, Neves G, Menegatti R, Fraga CA, Barreiro E, Eifler-Lima V, Rates SM, Costa TD. Pharmacokinetics and tissue distribution of a new heterocyclic N-phenylpiperazine derivative (LASSBio-581) in rats. European Journal of Pharmaceutical Sciences : Official Journal of the European Federation For Pharmaceutical Sciences. 26: 194-202. PMID 16076552 DOI: 10.1016/J.Ejps.2005.06.002 |
0.626 |
|
| 2003 |
Tasso L, Neves G, Menegatti R, Fraga CA, Barreiro EJ, Eifler-Lima VL, Rates SM, Dalla Costa T. Validated HPLC method for determination of LASSBio-581, a new heterocyclic N-phenylpiperazine derivative, in rat plasma. Journal of Pharmaceutical and Biomedical Analysis. 33: 1127-33. PMID 14656603 DOI: 10.1016/S0731-7085(03)00407-2 |
0.545 |
|
| 2003 |
Menegatti R, Cunha AC, Ferreira VF, Perreira EF, El-Nabawi A, Eldefrawi AT, Albuquerque EX, Neves G, Rates SM, Fraga CA, Barreiro EJ. Design, synthesis and pharmacological profile of novel dopamine D2 receptor ligands. Bioorganic & Medicinal Chemistry. 11: 4807-13. PMID 14556797 DOI: 10.1016/S0968-0896(03)00487-5 |
0.592 |
|
| 2003 |
Viana AF, Heckler AP, Fenner R, Rates SM. Antinociceptive activity of Hypericum caprifoliatum and Hypericum polyanthemum (Guttiferae). Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas Medicas E Biologicas. 36: 631-4. PMID 12715083 DOI: 10.1590/S0100-879X2003000500011 |
0.346 |
|
| 2003 |
Neves G, Fenner R, Heckler AP, Viana AF, Tasso L, Menegatti R, Fraga CA, Barreiro EJ, Dalla-Costa T, Rates SM. Dopaminergic profile of new heterocyclic N-phenylpiperazine derivatives. Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas Mã©Dicas E Biolã³Gicas / Sociedade Brasileira De BiofãSica ... [Et Al.]. 36: 625-9. PMID 12715082 DOI: 10.1590/S0100-879X2003000500010 |
0.647 |
|
| 2000 |
Daudt R, von Poser GL, Neves G, Rates SM. R. Daudt, G. L. Von poser, G. Neves and S. M. K. Rates, 'Screening for the antidepressant activity of some species of hypericum from south Brazil'. Phytotherapy research14(5) 2000, 344-346 Phytotherapy Research : Ptr. 14: 661. PMID 11114012 DOI: 10.1002/1099-1573(200012)14:8<661::Aid-Ptr806>3.0.Co;2-V |
0.529 |
|
| 2000 |
de-Paris F, Neves G, Salgueiro JB, Quevedo J, Izquierdo I, Rates SM. Psychopharmacological screening of Pfaffia glomerata Spreng. (Amarathanceae) in rodents. Journal of Ethnopharmacology. 73: 261-9. PMID 11025164 DOI: 10.1016/S0378-8741(00)00329-9 |
0.597 |
|
| 2000 |
Daudt R, von Poser GL, Neves G, Rates SM. Screening for the antidepressant activity of some species of Hypericum from South Brazil. Phytotherapy Research : Ptr. 14: 344-6. PMID 10925399 DOI: 10.1002/1099-1573(200008)14:5<344::Aid-Ptr586>3.0.Co;2-3 |
0.597 |
|
| 1998 |
Goloubkova TD, Heckler E, Rates SM, Henriques JA, Henriques AT. Inhibition of cytochrome P450-dependent monooxygenases by an alkaloid fraction from Helietta apiculata markedly potentiate the hypnotic action of pentobarbital. Journal of Ethnopharmacology. 60: 141-8. PMID 9582004 DOI: 10.1016/S0378-8741(97)00139-6 |
0.417 |
|
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