| Year |
Citation |
Score |
| 2023 |
Gonçalves PFR, Nunes LED, Andrade BDS, Silva MOLD, Souza INO, Assunção-Miranda I, Castro NG, Neves GA. Age-dependent memory impairment induced by co-exposure to nicotine and a synthetic cannabinoid in mice. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 127: 110821. PMID 37442332 DOI: 10.1016/j.pnpbp.2023.110821 |
0.637 |
|
| 2020 |
de Freitas Silva M, Tardelli Lima E, Pruccoli L, Castro NG, Guimarães MJR, M R da Silva F, Fonseca Nadur N, de Azevedo LL, Kümmerle AE, Guedes IA, Dardenne LE, Gontijo VS, Tarozzi A, Viegas C. Design, Synthesis and Biological Evaluation of Novel Triazole -acylhydrazone Hybrids for Alzheimer's Disease. Molecules (Basel, Switzerland). 25. PMID 32664425 DOI: 10.3390/Molecules25143165 |
0.448 |
|
| 2020 |
Marques AM, Macena MV, Cardoso AR, Hammes CSO, Pinheiro FML, Castro NG, Neves GA. Effects of combined 5-HT and cannabinoid receptor modulation on a schizophrenia-related prepulse inhibition deficit in mice. Psychopharmacology. PMID 32095916 DOI: 10.1007/S00213-020-05485-0 |
0.701 |
|
| 2019 |
Figueiredo CP, Barros-Aragão FGQ, Neris RLS, Frost PS, Soares C, Souza INO, Zeidler JD, Zamberlan DC, de Sousa VL, Souza AS, Guimarães ALA, Bellio M, Marcondes de Souza J, Alves-Leon SV, Neves GA, ... ... Castro NG, et al. Zika virus replicates in adult human brain tissue and impairs synapses and memory in mice. Nature Communications. 10: 3890. PMID 31488835 DOI: 10.1038/S41467-019-11866-7 |
0.653 |
|
| 2019 |
Nunes LE, Neves G, Castro N, Andrade B, Cunha G, Cunha N, Lione T, Nazareth N, Marques A, Ferreira B, Diniz F, Ferreira G. Blockade of cannabinoid type 2 receptor inhibits a working memory impairment relevant for schizophrenia Ibro Reports. 6: S447. DOI: 10.1016/J.Ibror.2019.07.1413 |
0.699 |
|
| 2018 |
Guimarães MZP, De Vecchi R, Vitória G, Sochacki JK, Paulsen BS, Lima I, Rodrigues da Silva F, da Costa RFM, Castro NG, Breton L, Rehen SK. Generation of iPSC-Derived Human Peripheral Sensory Neurons Releasing Substance P Elicited by TRPV1 Agonists. Frontiers in Molecular Neuroscience. 11: 277. PMID 30186108 DOI: 10.3389/Fnmol.2018.00277 |
0.301 |
|
| 2018 |
Dias Viegas FP, de Freitas Silva M, Divino da Rocha M, Castelli MR, Riquiel MM, Machado RP, Vaz SM, Simões de Lima LM, Mancini KC, Marques de Oliveira PC, Morais ÉP, Gontijo VS, da Silva FMR, D'Alincourt da Fonseca Peçanha D, Castro NG, et al. Design, synthesis and pharmacological evaluation of N-benzyl-piperidinyl-aryl-acylhydrazone derivatives as donepezil hybrids: Discovery of novel multi-target anti-alzheimer prototype drug candidates. European Journal of Medicinal Chemistry. 147: 48-65. PMID 29421570 DOI: 10.1016/J.Ejmech.2018.01.066 |
0.721 |
|
| 2017 |
Dias KS, de Paula CT, Dos Santos T, Souza IN, Boni MS, Guimarães MJ, da Silva FM, Castro NG, Neves GA, Veloso CC, Coelho MM, de Melo IS, Giusti FC, Giusti-Paiva A, da Silva ML, et al. Design, synthesis and evaluation of novel feruloyl-donepezil hybrids as potential multitarget drugs for the treatment of Alzheimer's disease. European Journal of Medicinal Chemistry. 130: 440-457. PMID 28282613 DOI: 10.1016/J.Ejmech.2017.02.043 |
0.672 |
|
| 2016 |
Lemes LF, de Andrade Ramos G, de Oliveira AS, da Silva FM, de Castro Couto G, da Silva Boni M, Guimarães MJ, Souza IN, Bartolini M, Andrisano V, do Nascimento Nogueira PC, Silveira ER, Brand GD, Soukup O, Korábečný J, ... ... Castro NG, et al. Cardanol-derived AChE inhibitors: Towards the development of dual binding derivatives for Alzheimer's disease. European Journal of Medicinal Chemistry. 108: 687-700. PMID 26735910 DOI: 10.1016/J.Ejmech.2015.12.024 |
0.72 |
|
| 2015 |
Petronilho ED, Rennó MD, Castro NG, da Silva FM, Pinto AD, Figueroa-Villar JD. Design, synthesis, and evaluation of guanylhydrazones as potential inhibitors or reactivators of acetylcholinesterase. Journal of Enzyme Inhibition and Medicinal Chemistry. 1-10. PMID 26558640 DOI: 10.3109/14756366.2015.1094468 |
0.441 |
|
| 2013 |
Setti-Perdigão P, Serrano MA, Flausino OA, Bolzani VS, Guimarães MZ, Castro NG. Erythrina mulungu alkaloids are potent inhibitors of neuronal nicotinic receptor currents in mammalian cells. Plos One. 8: e82726. PMID 24349349 DOI: 10.1371/Journal.Pone.0082726 |
0.364 |
|
| 2012 |
Diniz LP, Almeida JC, Tortelli V, Vargas Lopes C, Setti-Perdigão P, Stipursky J, Kahn SA, Romão LF, de Miranda J, Alves-Leon SV, de Souza JM, Castro NG, Panizzutti R, Gomes FC. Astrocyte-induced synaptogenesis is mediated by transforming growth factor β signaling through modulation of D-serine levels in cerebral cortex neurons. The Journal of Biological Chemistry. 287: 41432-45. PMID 23055518 DOI: 10.1074/Jbc.M112.380824 |
0.32 |
|
| 2012 |
Danuello A, Romeiro NC, Giesel GM, Pivatto M, Viegas C, Verli H, Barreiro EJ, Fraga CAM, Castro NG, Bolzani VS. Molecular docking and molecular dynamic studies of semi-synthetic piperidine alkaloids as acetylcholinesterase inhibitors Journal of the Brazilian Chemical Society. 23: 163-170. DOI: 10.1590/S0103-50532012000100023 |
0.306 |
|
| 2011 |
Marques-da-Silva C, Chaves MM, Castro NG, Coutinho-Silva R, Guimaraes MZ. Colchicine inhibits cationic dye uptake induced by ATP in P2X2 and P2X7 receptor-expressing cells: implications for its therapeutic action. British Journal of Pharmacology. 163: 912-26. PMID 21306580 DOI: 10.1111/J.1476-5381.2011.01254.X |
0.33 |
|
| 2010 |
Tributino JL, Santos ML, Mesquita CM, Lima CK, Silva LL, Maia RC, Duarte CD, Barreiro EJ, Fraga CA, Castro NG, Miranda AL, Guimaraes MZ. LASSBio-881: an N-acylhydrazone transient receptor potential vanilloid subfamily type 1 antagonist orally effective against the hypernociception induced by capsaicin or partial sciatic ligation. British Journal of Pharmacology. 159: 1716-23. PMID 20401963 DOI: 10.1111/J.1476-5381.2010.00672.X |
0.377 |
|
| 2009 |
Lima JA, Costa RS, Epifânio RA, Castro NG, Rocha MS, Pinto AC. Geissospermum vellosii stembark: anticholinesterase activity and improvement of scopolamine-induced memory deficits. Pharmacology, Biochemistry, and Behavior. 92: 508-13. PMID 19463267 DOI: 10.1016/J.Pbb.2009.01.024 |
0.371 |
|
| 2009 |
Tributino JL, Duarte CD, Corrêa RS, Doriguetto AC, Ellena J, Romeiro NC, Castro NG, Miranda AL, Barreiro EJ, Fraga CA. Novel 6-methanesulfonamide-3,4-methylenedioxyphenyl-N-acylhydrazones: orally effective anti-inflammatory drug candidates. Bioorganic & Medicinal Chemistry. 17: 1125-31. PMID 19135376 DOI: 10.1016/J.Bmc.2008.12.045 |
0.33 |
|
| 2008 |
Castro NG, Costa RS, Pimentel LS, Danuello A, Romeiro NC, Viegas C, Barreiro EJ, Fraga CA, Bolzani VS, Rocha MS. CNS-selective noncompetitive cholinesterase inhibitors derived from the natural piperidine alkaloid (-)-spectaline. European Journal of Pharmacology. 580: 339-49. PMID 18096154 DOI: 10.1016/J.Ejphar.2007.11.035 |
0.373 |
|
| 2006 |
Santos HR, Ribeiro HS, Setti-Perdigão P, Albuquerque EX, Castro NG. The magnitude of alpha7 nicotinic receptor currents in rat hippocampal neurons is dependent upon GABAergic activity and depolarization. The Journal of Pharmacology and Experimental Therapeutics. 319: 376-85. PMID 16837558 DOI: 10.1124/Jpet.106.106385 |
0.326 |
|
| 2005 |
Viegas C, Bolzani VS, Pimentel LS, Castro NG, Cabral RF, Costa RS, Floyd C, Rocha MS, Young MC, Barreiro EJ, Fraga CA. New selective acetylcholinesterase inhibitors designed from natural piperidine alkaloids. Bioorganic & Medicinal Chemistry. 13: 4184-90. PMID 15878668 DOI: 10.1016/J.Bmc.2005.04.030 |
0.423 |
|
| 2005 |
Pessôa RF, Castro NG, Noël F. Binding of [3H]MK-801 in subcellular fractions of Schistosoma mansoni: Evidence for interaction with nicotinic receptors Biochemical Pharmacology. 69: 1509-1516. PMID 15857615 DOI: 10.1016/J.Bcp.2005.03.005 |
0.616 |
|
| 2004 |
Lima PG, Caruso RR, Alves SO, Pessôa RF, Mendonça-Silva DL, Nunes RJ, Noël F, Castro NG, Costa PR. Stereoselective synthesis and preliminary evaluation of new D-3-heteroarylcarbonylalanines as ligands of the NMDA receptor. Bioorganic & Medicinal Chemistry Letters. 14: 4399-403. PMID 15357961 DOI: 10.1016/J.Bmcl.2004.06.062 |
0.624 |
|
| 2004 |
Lopes DV, Caruso RR, Castro NG, Costa PR, da Silva AJ, Noël F. Characterization of a new synthetic isoflavonoid with inverse agonist activity at the central benzodiazepine receptor. European Journal of Pharmacology. 495: 87-96. PMID 15249156 DOI: 10.1016/J.Ejphar.2004.05.026 |
0.644 |
|
| 2004 |
Lopes DVS, Caruso RRB, Castro NG, Costa PRR, Silva AJMd, Noël F. Corrigendum to “Characterization of a new synthetic isoflavonoid with inverse agonist activity at the central benzodiazepine receptor” [Eur. J. Pharmacol. 495 (2004) 87–96] European Journal of Pharmacology. 502: 157. DOI: 10.1016/J.Ejphar.2004.08.029 |
0.589 |
|
| 2003 |
Barreiro EJ, Camara CA, Verli H, Brazil-Más L, Castro NG, Cintra WM, Aracava Y, Rodrigues CR, Fraga CA. Design, synthesis, and pharmacological profile of novel fused pyrazolo[4,3-d]pyridine and pyrazolo[3,4-b][1,8]naphthyridine isosteres: a new class of potent and selective acetylcholinesterase inhibitors. Journal of Medicinal Chemistry. 46: 1144-52. PMID 12646025 DOI: 10.1021/Jm020391N |
0.433 |
|
| 2003 |
Santos MD, Pereira EF, Aracava Y, Castro NG, Fawcett WP, Randall WR, Albuquerque EX. Low concentrations of pyridostigmine prevent soman-induced inhibition of GABAergic transmission in the central nervous system: involvement of muscarinic receptors. The Journal of Pharmacology and Experimental Therapeutics. 304: 254-65. PMID 12490599 DOI: 10.1124/Jpet.102.043109 |
0.353 |
|
| 2002 |
da Silva AJ, Buarque CD, Brito FV, Aurelian L, Macedo LF, Malkas LH, Hickey RJ, Lopes DV, Noël F, Murakami YL, Silva NM, Melo PA, Caruso RR, Castro NG, Costa PR. Synthesis and preliminary pharmacological evaluation of new (+/-) 1,4-naphthoquinones structurally related to lapachol. Bioorganic & Medicinal Chemistry. 10: 2731-8. PMID 12057662 DOI: 10.1016/S0968-0896(02)00100-1 |
0.627 |
|
| 2000 |
Mike A, Castro NG, Albuquerque EX. Choline and acetylcholine have similar kinetic properties of activation and desensitization on the alpha7 nicotinic receptors in rat hippocampal neurons. Brain Research. 882: 155-68. PMID 11056195 DOI: 10.1016/S0006-8993(00)02863-8 |
0.341 |
|
| 1999 |
Castro NG, de Mello MC, de Mello FG, Aracava Y. Direct inhibition of the N-methyl-D-aspartate receptor channel by dopamine and (+)-SKF38393. British Journal of Pharmacology. 126: 1847-55. PMID 10372829 DOI: 10.1038/Sj.Bjp.0702479 |
0.344 |
|
| 1995 |
Albuquerque EX, Pereira EF, Castro NG, Alkondon M, Reinhardt S, Schröder H, Maelicke A. Nicotinic receptor function in the mammalian central nervous system. Annals of the New York Academy of Sciences. 757: 48-72. PMID 7611705 DOI: 10.1111/J.1749-6632.1995.Tb17464.X |
0.335 |
|
| 1995 |
Albuquerque EX, Pereira EFR, Castro NG, Alkondon M. Neuronal nicotinic receptors: Function, modulation and structure Seminars in the Neurosciences. 7: 91-101. DOI: 10.1006/Smns.1995.0011 |
0.315 |
|
| 1994 |
Montes JG, Alkondon M, Pereira EFR, Castro NG, Albuquerque EX. Electrophysiological Methods for the Study of Neuronal Nicotinic Acetylcholine Receptor Ion Channels Methods in Neurosciences. 19: 121-147. DOI: 10.1016/B978-0-12-185287-0.50013-2 |
0.307 |
|
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