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Francis V. Chisari, M.D. - Publications

Affiliations: 
Scripps Research Institute, La Jolla, La Jolla, CA, United States 
Area:
Immunobiology and Pathogenesis of Hepatitis B and C Virus Infection
Website:
https://www.scripps.edu/research/faculty/chisari
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256 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Fumagalli V, Di Lucia P, Venzin V, Bono EB, Jordan R, Frey CR, Delaney W, Chisari FV, Guidotti LG, Iannacone M. Serum HBsAg clearance has minimal impact on CD8+ T cell responses in mouse models of HBV infection. The Journal of Experimental Medicine. 217. PMID 32761167 DOI: 10.1084/Jem.20200298  0.51
2019 Revill PA, Chisari FV, Block JM, Dandri M, Gehring AJ, Guo H, Hu J, Kramvis A, Lampertico P, Janssen HLA, Levrero M, Li W, Liang TJ, Lim SG, Lu F, et al. A global scientific strategy to cure hepatitis B. The Lancet. Gastroenterology & Hepatology. PMID 30981686 DOI: 10.1016/S2468-1253(19)30119-0  0.536
2018 Alter HJ, Chisari FV. Is Elimination of Hepatitis B and C a Pipe Dream or Reality? Gastroenterology. PMID 30593797 DOI: 10.1053/j.gastro.2018.12.015  0.316
2018 Alter HJ, Chisari FV. Is Elimination of Hepatitis B and C a Pipe Dream or Reality? Gastroenterology. PMID 30593764 DOI: 10.1053/J.Gastro.2018.12.015  0.427
2017 Alter H, Block TM, Brown N, Brownstein A, Brosgart C, Chang KM, Chen PJ, Chisari FV, Cohen C, El-Serag H, Feld J, Gish R, Glenn J, Greten T, Guo H, et al. A Research Agenda for Curing Chronic Hepatitis B Virus Infection. Hepatology (Baltimore, Md.). PMID 28877549 DOI: 10.1002/Hep.29509  0.526
2017 Fioravanti J, Di Lucia P, Magini D, Moalli F, Boni C, Benechet AP, Fumagalli V, Inverso D, Vecchi A, Fiocchi A, Wieland S, Purcell R, Ferrari C, Chisari FV, Guidotti LG, et al. Effector CD8(+) T cell-derived interleukin-10 enhances acute liver immunopathology. Journal of Hepatology. PMID 28483675 DOI: 10.1016/J.Jhep.2017.04.020  0.477
2015 Guidotti LG, Isogawa M, Chisari FV. Host-virus interactions in hepatitis B virus infection. Current Opinion in Immunology. 36: 61-6. PMID 26186123 DOI: 10.1016/J.Coi.2015.06.016  0.59
2015 Guidotti LG, Inverso D, Sironi L, Di Lucia P, Fioravanti J, Ganzer L, Fiocchi A, Vacca M, Aiolfi R, Sammicheli S, Mainetti M, Cataudella T, Raimondi A, Gonzalez-Aseguinolaza G, Protzer U, ... ... Chisari FV, et al. Immunosurveillance of the liver by intravascular effector CD8(+) T cells. Cell. 161: 486-500. PMID 25892224 DOI: 10.1016/J.Cell.2015.03.005  0.43
2015 Longatti A, Boyd B, Chisari FV. Virion-independent transfer of replication-competent hepatitis C virus RNA between permissive cells. Journal of Virology. 89: 2956-61. PMID 25505060 DOI: 10.1128/Jvi.02721-14  0.482
2014 Chisari FV, Mason WS, Seeger C. Virology. Comment on "Specific and nonhepatotoxic degradation of nuclear hepatitis B virus cccDNA". Science (New York, N.Y.). 344: 1237. PMID 24926010 DOI: 10.1126/Science.1254082  0.523
2014 Wieland SF, Asabe S, Engle RE, Purcell RH, Chisari FV. Limited hepatitis B virus replication space in the chronically hepatitis C virus-infected liver. Journal of Virology. 88: 5184-8. PMID 24522924 DOI: 10.1128/Jvi.03553-13  0.568
2014 Wieland SF, Takahashi K, Boyd B, Whitten-Bauer C, Ngo N, de la Torre JC, Chisari FV. Human plasmacytoid dendritic cells sense lymphocytic choriomeningitis virus-infected cells in vitro. Journal of Virology. 88: 752-7. PMID 24155390 DOI: 10.1128/Jvi.01714-13  0.484
2014 Wieland S, Makowska Z, Campana B, Calabrese D, Dill MT, Chung J, Chisari FV, Heim MH. Simultaneous detection of hepatitis C virus and interferon stimulated gene expression in infected human liver. Hepatology (Baltimore, Md.). 59: 2121-30. PMID 24122862 DOI: 10.1002/Hep.26770  0.513
2013 Isogawa M, Chung J, Murata Y, Kakimi K, Chisari FV. CD40 activation rescues antiviral CD8⁺ T cells from PD-1-mediated exhaustion. Plos Pathogens. 9: e1003490. PMID 23853599 DOI: 10.1371/Journal.Ppat.1003490  0.462
2013 Friesland M, Mingorance L, Chung J, Chisari FV, Gastaminza P. Sigma-1 receptor regulates early steps of viral RNA replication at the onset of hepatitis C virus infection. Journal of Virology. 87: 6377-90. PMID 23536676 DOI: 10.1128/Jvi.03557-12  0.46
2012 Dreux M, Garaigorta U, Boyd B, Décembre E, Chung J, Whitten-Bauer C, Wieland S, Chisari FV. Short-range exosomal transfer of viral RNA from infected cells to plasmacytoid dendritic cells triggers innate immunity. Cell Host & Microbe. 12: 558-70. PMID 23084922 DOI: 10.1016/J.Chom.2012.08.010  0.455
2012 Garaigorta U, Heim MH, Boyd B, Wieland S, Chisari FV. Hepatitis C virus (HCV) induces formation of stress granules whose proteins regulate HCV RNA replication and virus assembly and egress. Journal of Virology. 86: 11043-56. PMID 22855484 DOI: 10.1128/Jvi.07101-11  0.488
2012 Sitia G, Aiolfi R, Di Lucia P, Mainetti M, Fiocchi A, Mingozzi F, Esposito A, Ruggeri ZM, Chisari FV, Iannacone M, Guidotti LG. Antiplatelet therapy prevents hepatocellular carcinoma and improves survival in a mouse model of chronic hepatitis B. Proceedings of the National Academy of Sciences of the United States of America. 109: E2165-72. PMID 22753481 DOI: 10.1073/Pnas.1209182109  0.496
2011 Montero A, Gastaminza P, Law M, Cheng G, Chisari FV, Ghadiri MR. Self-assembling peptide nanotubes with antiviral activity against hepatitis C virus. Chemistry & Biology. 18: 1453-62. PMID 22118679 DOI: 10.1016/J.Chembiol.2011.08.017  0.442
2011 MacPherson JI, Sidders B, Wieland S, Zhong J, Targett-Adams P, Lohmann V, Backes P, Delpuech-Adams O, Chisari F, Lewis M, Parkinson T, Robertson DL. An integrated transcriptomic and meta-analysis of hepatoma cells reveals factors that influence susceptibility to HCV infection. Plos One. 6: e25584. PMID 22046242 DOI: 10.1371/Journal.Pone.0025584  0.451
2011 Dreux M, Chisari FV. Impact of the autophagy machinery on hepatitis C virus infection. Viruses. 3: 1342-57. PMID 21994783 DOI: 10.3390/V3081342  0.465
2011 Sitia G, Iannacone M, Aiolfi R, Isogawa M, van Rooijen N, Scozzesi C, Bianchi ME, von Andrian UH, Chisari FV, Guidotti LG. Kupffer cells hasten resolution of liver immunopathology in mouse models of viral hepatitis. Plos Pathogens. 7: e1002061. PMID 21655107 DOI: 10.1371/Journal.Ppat.1002061  0.547
2011 Gastaminza P, Pitram SM, Dreux M, Krasnova LB, Whitten-Bauer C, Dong J, Chung J, Fokin VV, Sharpless KB, Chisari FV. Antiviral stilbene 1,2-diamines prevent initiation of hepatitis C virus RNA replication at the outset of infection. Journal of Virology. 85: 5513-23. PMID 21430055 DOI: 10.1128/Jvi.02116-10  0.45
2010 Gastaminza P, Dryden KA, Boyd B, Wood MR, Law M, Yeager M, Chisari FV. Ultrastructural and biophysical characterization of hepatitis C virus particles produced in cell culture. Journal of Virology. 84: 10999-1009. PMID 20686033 DOI: 10.1128/Jvi.00526-10  0.385
2010 Chatterji U, Lim P, Bobardt MD, Wieland S, Cordek DG, Vuagniaux G, Chisari F, Cameron CE, Targett-Adams P, Parkinson T, Gallay PA. HCV resistance to cyclosporin A does not correlate with a resistance of the NS5A-cyclophilin A interaction to cyclophilin inhibitors. Journal of Hepatology. 53: 50-6. PMID 20451281 DOI: 10.1016/J.Jhep.2010.01.041  0.365
2010 Dreux M, Chisari FV. Viruses and the autophagy machinery. Cell Cycle (Georgetown, Tex.). 9: 1295-1307. PMID 20305376 DOI: 10.4161/Cc.9.7.11109  0.369
2010 Takahashi K, Asabe S, Wieland S, Garaigorta U, Gastaminza P, Isogawa M, Chisari FV. Plasmacytoid dendritic cells sense hepatitis C virus-infected cells, produce interferon, and inhibit infection. Proceedings of the National Academy of Sciences of the United States of America. 107: 7431-6. PMID 20231459 DOI: 10.1073/Pnas.1002301107  0.537
2010 Bissig KD, Wieland SF, Tran P, Isogawa M, Le TT, Chisari FV, Verma IM. Human liver chimeric mice provide a model for hepatitis B and C virus infection and treatment. The Journal of Clinical Investigation. 120: 924-30. PMID 20179355 DOI: 10.1172/Jci40094  0.543
2010 Chisari FV, Isogawa M, Wieland SF. Pathogenesis of hepatitis B virus infection. Pathologie-Biologie. 58: 258-66. PMID 20116937 DOI: 10.1016/J.Patbio.2009.11.001  0.6
2010 Yang PL, Althage A, Chung J, Maier H, Wieland S, Isogawa M, Chisari FV. Immune effectors required for hepatitis B virus clearance. Proceedings of the National Academy of Sciences of the United States of America. 107: 798-802. PMID 20080755 DOI: 10.1073/Pnas.0913498107  0.697
2010 Gastaminza P, Whitten-Bauer C, Chisari FV. Unbiased probing of the entire hepatitis C virus life cycle identifies clinical compounds that target multiple aspects of the infection. Proceedings of the National Academy of Sciences of the United States of America. 107: 291-6. PMID 19995961 DOI: 10.1073/Pnas.0912966107  0.471
2010 Bandi P, Garcia ML, Booth CJ, Chisari FV, Robek MD. Bortezomib inhibits hepatitis B virus replication in transgenic mice. Antimicrobial Agents and Chemotherapy. 54: 749-56. PMID 19949053 DOI: 10.1128/Aac.01101-09  0.537
2009 Garaigorta U, Chisari FV. Hepatitis C virus blocks interferon effector function by inducing protein kinase R phosphorylation. Cell Host & Microbe. 6: 513-22. PMID 20006840 DOI: 10.1016/J.Chom.2009.11.004  0.492
2009 Dreux M, Chisari FV. Autophagy proteins promote hepatitis C virus replication. Autophagy. 5: 1224-5. PMID 19844160 DOI: 10.4161/Auto.5.8.10219  0.481
2009 Dreux M, Gastaminza P, Wieland SF, Chisari FV. The autophagy machinery is required to initiate hepatitis C virus replication. Proceedings of the National Academy of Sciences of the United States of America. 106: 14046-51. PMID 19666601 DOI: 10.1073/Pnas.0907344106  0.491
2009 Asabe S, Wieland SF, Chattopadhyay PK, Roederer M, Engle RE, Purcell RH, Chisari FV. The size of the viral inoculum contributes to the outcome of hepatitis B virus infection. Journal of Virology. 83: 9652-62. PMID 19625407 DOI: 10.1128/Jvi.00867-09  0.507
2008 Bukh J, Thimme R, Meunier JC, Faulk K, Spangenberg HC, Chang KM, Satterfield W, Chisari FV, Purcell RH. Previously infected chimpanzees are not consistently protected against reinfection or persistent infection after reexposure to the identical hepatitis C virus strain. Journal of Virology. 82: 8183-95. PMID 18550671 DOI: 10.1128/Jvi.00142-08  0.505
2008 Bobardt MD, Cheng G, de Witte L, Selvarajah S, Chatterji U, Sanders-Beer BE, Geijtenbeek TB, Chisari FV, Gallay PA. Hepatitis C virus NS5A anchor peptide disrupts human immunodeficiency virus. Proceedings of the National Academy of Sciences of the United States of America. 105: 5525-30. PMID 18378908 DOI: 10.1073/Pnas.0801388105  0.436
2008 Cheng G, Montero A, Gastaminza P, Whitten-Bauer C, Wieland SF, Isogawa M, Fredericksen B, Selvarajah S, Gallay PA, Ghadiri MR, Chisari FV. A virocidal amphipathic {alpha}-helical peptide that inhibits hepatitis C virus infection in vitro. Proceedings of the National Academy of Sciences of the United States of America. 105: 3088-93. PMID 18287023 DOI: 10.1073/Pnas.0712380105  0.442
2008 Iannacone M, Sitia G, Isogawa M, Whitmire JK, Marchese P, Chisari FV, Ruggeri ZM, Guidotti LG. Platelets prevent IFN-alpha/beta-induced lethal hemorrhage promoting CTL-dependent clearance of lymphocytic choriomeningitis virus. Proceedings of the National Academy of Sciences of the United States of America. 105: 629-34. PMID 18184798 DOI: 10.1073/Pnas.0711200105  0.377
2008 Gastaminza P, Cheng G, Wieland S, Zhong J, Liao W, Chisari FV. Cellular determinants of hepatitis C virus assembly, maturation, degradation, and secretion. Journal of Virology. 82: 2120-9. PMID 18077707 DOI: 10.1128/Jvi.02053-07  0.432
2008 Law M, Maruyama T, Lewis J, Giang E, Tarr AW, Stamataki Z, Gastaminza P, Chisari FV, Jones IM, Fox RI, Ball JK, McKeating JA, Kneteman NM, Burton DR. Broadly neutralizing antibodies protect against hepatitis C virus quasispecies challenge. Nature Medicine. 14: 25-7. PMID 18064037 DOI: 10.1038/Nm1698  0.471
2007 Pedersen IM, Cheng G, Wieland S, Volinia S, Croce CM, Chisari FV, David M. Interferon modulation of cellular microRNAs as an antiviral mechanism. Nature. 449: 919-22. PMID 17943132 DOI: 10.1038/Nature06205  0.341
2007 Cheng G, Zhong J, Chung J, Chisari FV. Double-stranded DNA and double-stranded RNA induce a common antiviral signaling pathway in human cells. Proceedings of the National Academy of Sciences of the United States of America. 104: 9035-40. PMID 17517627 DOI: 10.1073/Pnas.0703285104  0.447
2007 Sakai A, Takikawa S, Thimme R, Meunier JC, Spangenberg HC, Govindarajan S, Farci P, Emerson SU, Chisari FV, Purcell RH, Bukh J. In vivo study of the HC-TN strain of hepatitis C virus recovered from a patient with fulminant hepatitis: RNA transcripts of a molecular clone (pHC-TN) are infectious in chimpanzees but not in Huh7.5 cells. Journal of Virology. 81: 7208-19. PMID 17409145 DOI: 10.1128/Jvi.01774-06  0.428
2007 Maier H, Isogawa M, Freeman GJ, Chisari FV. PD-1:PD-L1 interactions contribute to the functional suppression of virus-specific CD8+ T lymphocytes in the liver. Journal of Immunology (Baltimore, Md. : 1950). 178: 2714-20. PMID 17312113 DOI: 10.4049/Jimmunol.178.5.2714  0.405
2007 Robek MD, Garcia ML, Boyd BS, Chisari FV. Role of immunoproteasome catalytic subunits in the immune response to hepatitis B virus. Journal of Virology. 81: 483-91. PMID 17079320 DOI: 10.1128/Jvi.01779-06  0.557
2007 Kapadia SB, Barth H, Baumert T, McKeating JA, Chisari FV. Initiation of hepatitis C virus infection is dependent on cholesterol and cooperativity between CD81 and scavenger receptor B type I. Journal of Virology. 81: 374-83. PMID 17050612 DOI: 10.1128/Jvi.01134-06  0.453
2006 Guidotti LG, Chisari FV. Immunobiology and pathogenesis of viral hepatitis. Annual Review of Pathology. 1: 23-61. PMID 18039107 DOI: 10.1146/Annurev.Pathol.1.110304.100230  0.597
2006 Uprichard SL, Chung J, Chisari FV, Wakita T. Replication of a hepatitis C virus replicon clone in mouse cells. Virology Journal. 3: 89. PMID 17069661 DOI: 10.1186/1743-422X-3-89  0.483
2006 Sainz B, Chisari FV. Production of infectious hepatitis C virus by well-differentiated, growth-arrested human hepatoma-derived cells. Journal of Virology. 80: 10253-7. PMID 17005703 DOI: 10.1128/Jvi.01059-06  0.483
2006 Gastaminza P, Kapadia SB, Chisari FV. Differential biophysical properties of infectious intracellular and secreted hepatitis C virus particles. Journal of Virology. 80: 11074-81. PMID 16956946 DOI: 10.1128/Jvi.01150-06  0.424
2006 Zhong J, Gastaminza P, Chung J, Stamataki Z, Isogawa M, Cheng G, McKeating JA, Chisari FV. Persistent hepatitis C virus infection in vitro: coevolution of virus and host. Journal of Virology. 80: 11082-93. PMID 16956932 DOI: 10.1128/Jvi.01307-06  0.517
2006 Dryden KA, Wieland SF, Whitten-Bauer C, Gerin JL, Chisari FV, Yeager M. Native hepatitis B virions and capsids visualized by electron cryomicroscopy. Molecular Cell. 22: 843-50. PMID 16793552 DOI: 10.1016/J.Molcel.2006.04.025  0.514
2006 Sidney J, Asabe S, Peters B, Purton KA, Chung J, Pencille TJ, Purcell R, Walker CM, Chisari FV, Sette A. Detailed characterization of the peptide binding specificity of five common Patr class I MHC molecules. Immunogenetics. 58: 559-70. PMID 16791621 DOI: 10.1007/S00251-006-0131-4  0.353
2006 Cheng G, Zhong J, Chisari FV. Inhibition of dsRNA-induced signaling in hepatitis C virus-infected cells by NS3 protease-dependent and -independent mechanisms. Proceedings of the National Academy of Sciences of the United States of America. 103: 8499-504. PMID 16707574 DOI: 10.1073/Pnas.0602957103  0.446
2006 Kimura K, Moriwaki H, Nagaki M, Saio M, Nakamoto Y, Naito M, Kuwata K, Chisari FV. Pathogenic role of B cells in anti-CD40-induced necroinflammatory liver disease. The American Journal of Pathology. 168: 786-95. PMID 16507894 DOI: 10.2353/Ajpath.2006.050314  0.429
2006 Iannacone M, Sitia G, Isogawa M, Whitmire JK, Marchese P, Chisari FV, Ruggeri ZM, Guidotti LG. Platelets Mediate Clearance of Lymphocytic Choriomeningitis Virus Infection Preventing Lethal Hemorrhage. Blood. 108: 1089-1089. DOI: 10.1182/Blood.V108.11.1089.1089  0.449
2006 Chisari F. O.068 Robust hepatitis C virus infection in vitro: coevolution of virus and host Journal of Clinical Virology. 36: S21. DOI: 10.1016/S1386-6532(06)80073-9  0.391
2005 Murray JM, Wieland SF, Purcell RH, Chisari FV. Dynamics of hepatitis B virus clearance in chimpanzees. Proceedings of the National Academy of Sciences of the United States of America. 102: 17780-5. PMID 16306261 DOI: 10.1073/Pnas.0508913102  0.563
2005 Iannacone M, Sitia G, Isogawa M, Marchese P, Castro MG, Lowenstein PR, Chisari FV, Ruggeri ZM, Guidotti LG. Platelets mediate cytotoxic T lymphocyte-induced liver damage. Nature Medicine. 11: 1167-9. PMID 16258538 DOI: 10.1038/nm1317  0.394
2005 Gilbert RJ, Beales L, Blond D, Simon MN, Lin BY, Chisari FV, Stuart DI, Rowlands DJ. Hepatitis B small surface antigen particles are octahedral. Proceedings of the National Academy of Sciences of the United States of America. 102: 14783-8. PMID 16203986 DOI: 10.1073/Pnas.0505062102  0.358
2005 Chisari FV. Unscrambling hepatitis C virus-host interactions. Nature. 436: 930-2. PMID 16107831 DOI: 10.1038/Nature04076  0.497
2005 Isogawa M, Furuichi Y, Chisari FV. Oscillating CD8+ T cell effector functions after antigen recognition in the liver Immunity. 23: 53-63. PMID 16039579 DOI: 10.1016/J.Immuni.2005.05.005  0.571
2005 Wieland SF, Chisari FV. Stealth and cunning: hepatitis B and hepatitis C viruses. Journal of Virology. 79: 9369-80. PMID 16014900 DOI: 10.1128/Jvi.79.15.9369-9380.2005  0.589
2005 Wieland SF, Eustaquio A, Whitten-Bauer C, Boyd B, Chisari FV. Interferon prevents formation of replication-competent hepatitis B virus RNA-containing nucleocapsids. Proceedings of the National Academy of Sciences of the United States of America. 102: 9913-7. PMID 15994231 DOI: 10.1073/Pnas.0504273102  0.517
2005 Zhong J, Gastaminza P, Cheng G, Kapadia S, Kato T, Burton DR, Wieland SF, Uprichard SL, Wakita T, Chisari FV. Robust hepatitis C virus infection in vitro. Proceedings of the National Academy of Sciences of the United States of America. 102: 9294-9. PMID 15939869 DOI: 10.1073/Pnas.0503596102  0.491
2005 Isogawa M, Robek MD, Furuichi Y, Chisari FV. Toll-like receptor signaling inhibits hepatitis B virus replication in vivo. Journal of Virology. 79: 7269-72. PMID 15890966 DOI: 10.1128/Jvi.79.11.7269-7272.2005  0.451
2005 Robek MD, Boyd BS, Chisari FV. Lambda interferon inhibits hepatitis B and C virus replication. Journal of Virology. 79: 3851-4. PMID 15731279 DOI: 10.1128/Jvi.79.6.3851-3854.2005  0.505
2005 Isogawa M, Kakimi K, Kamamoto H, Protzer U, Chisari FV. Differential dynamics of the peripheral and intrahepatic cytotoxic T lymphocyte response to hepatitis B surface antigen. Virology. 333: 293-300. PMID 15721363 DOI: 10.1016/J.Virol.2005.01.004  0.577
2005 Chen M, Sällberg M, Hughes J, Jones J, Guidotti LG, Chisari FV, Billaud JN, Milich DR. Immune tolerance split between hepatitis B virus precore and core proteins. Journal of Virology. 79: 3016-27. PMID 15709022 DOI: 10.1128/Jvi.79.5.3016-3027.2005  0.546
2005 Kapadia SB, Chisari FV. Hepatitis C virus RNA replication is regulated by host geranylgeranylation and fatty acids. Proceedings of the National Academy of Sciences of the United States of America. 102: 2561-6. PMID 15699349 DOI: 10.1073/Pnas.0409834102  0.469
2005 Neumann-Haefelin C, Blum HE, Chisari FV, Thimme R. T cell response in hepatitis C virus infection Journal of Clinical Virology. 32: 75-85. PMID 15653409 DOI: 10.1016/J.Jcv.2004.05.008  0.577
2005 Uprichard SL, Boyd B, Althage A, Chisari FV. Clearance of hepatitis B virus from the liver of transgenic mice by short hairpin RNAs. Proceedings of the National Academy of Sciences of the United States of America. 102: 773-8. PMID 15640346 DOI: 10.1073/Pnas.0409028102  0.547
2004 Chen MT, Billaud JN, Sällberg M, Guidotti LG, Chisari FV, Jones J, Hughes J, Milich DR. A function of the hepatitis B virus precore protein is to regulate the immune response to the core antigen. Proceedings of the National Academy of Sciences of the United States of America. 101: 14913-8. PMID 15469922 DOI: 10.1073/Pnas.0406282101  0.532
2004 Wieland S, Thimme R, Purcell RH, Chisari FV. Genomic analysis of the host response to hepatitis B virus infection. Proceedings of the National Academy of Sciences of the United States of America. 101: 6669-74. PMID 15100412 DOI: 10.1073/pnas.0401771101  0.498
2004 Sitia G, Isogawa M, Iannacone M, Campbell IL, Chisari FV, Guidotti LG. MMPs are required for recruitment of antigen-nonspecific mononuclear cells into the liver by CTLs. The Journal of Clinical Investigation. 113: 1158-67. PMID 15085195 DOI: 10.1172/Jci21087  0.508
2004 Wieland SF, Spangenberg HC, Thimme R, Purcell RH, Chisari FV. Expansion and contraction of the hepatitis B virus transcriptional template in infected chimpanzees. Proceedings of the National Academy of Sciences of the United States of America. 101: 2129-34. PMID 14764900 DOI: 10.1073/Pnas.0308478100  0.585
2004 Robek MD, Boyd BS, Wieland SF, Chisari FV. Signal transduction pathways that inhibit hepatitis B virus replication. Proceedings of the National Academy of Sciences of the United States of America. 101: 1743-7. PMID 14757813 DOI: 10.1073/Pnas.0308340100  0.463
2003 Kapadia SB, Brideau-Andersen A, Chisari FV. Interference of hepatitis C virus RNA replication by short interfering RNAs. Proceedings of the National Academy of Sciences of the United States of America. 100: 2014-8. PMID 12566571 DOI: 10.1073/Pnas.252783999  0.488
2003 Uprichard SL, Wieland SF, Althage A, Chisari FV. Transcriptional and posttranscriptional control of hepatitis B virus gene expression. Proceedings of the National Academy of Sciences of the United States of America. 100: 1310-5. PMID 12552098 DOI: 10.1073/Pnas.252773599  0.566
2003 Wieland SF, Vega RG, Müller R, Evans CF, Hilbush B, Guidotti LG, Sutcliffe JG, Schultz PG, Chisari FV. Searching for interferon-induced genes that inhibit hepatitis B virus replication in transgenic mouse hepatocytes. Journal of Virology. 77: 1227-36. PMID 12502840 DOI: 10.1128/Jvi.77.2.1227-1236.2003  0.579
2003 Thimme R, Wieland S, Steiger C, Ghrayeb J, Reimann KA, Purcell RH, Chisari FV. CD8(+) T cells mediate viral clearance and disease pathogenesis during acute hepatitis B virus infection. Journal of Virology. 77: 68-76. PMID 12477811 DOI: 10.1128/Jvi.77.1.68-76.2003  0.491
2003 Bukh J, Thimme R, Satterfield WC, Meunier J, Forms X, Yanagi M, Emerson SU, Spangenberg HC, Chang KM, Chisari FV, Purcell RH. Persistence of hepatitis C after homolgous monoclonal re-challenge associated with the emergence of new virus variants Gastroenterology. 124: A710. DOI: 10.1016/S0016-5085(03)83588-6  0.464
2002 Thimme R, Bukh J, Spangenberg HC, Wieland S, Pemberton J, Steiger C, Govindarajan S, Purcell RH, Chisari FV. Viral and immunological determinants of hepatitis C virus clearance, persistence, and disease. Proceedings of the National Academy of Sciences of the United States of America. 99: 15661-8. PMID 12441397 DOI: 10.1073/Pnas.202608299  0.561
2002 Su AI, Pezacki JP, Wodicka L, Brideau AD, Supekova L, Thimme R, Wieland S, Bukh J, Purcell RH, Schultz PG, Chisari FV. Genomic analysis of the host response to hepatitis C virus infection. Proceedings of the National Academy of Sciences of the United States of America. 99: 15669-74. PMID 12441396 DOI: 10.1073/Pnas.202608199  0.618
2002 Kimura K, Kakimi K, Wieland S, Guidotti LG, Chisari FV. Activated intrahepatic antigen-presenting cells inhibit hepatitis B virus replication in the liver of transgenic mice. Journal of Immunology (Baltimore, Md. : 1950). 169: 5188-95. PMID 12391236 DOI: 10.4049/Jimmunol.169.9.5188  0.513
2002 Yang PL, Althage A, Chung J, Chisari FV. Hydrodynamic injection of viral DNA: a mouse model of acute hepatitis B virus infection. Proceedings of the National Academy of Sciences of the United States of America. 99: 13825-30. PMID 12374864 DOI: 10.1073/Pnas.202398599  0.728
2002 Sitia G, Isogawa M, Kakimi K, Wieland SF, Chisari FV, Guidotti LG. Depletion of neutrophils blocks the recruitment of antigen-nonspecific cells into the liver without affecting the antiviral activity of hepatitis B virus-specific cytotoxic T lymphocytes. Proceedings of the National Academy of Sciences of the United States of America. 99: 13717-22. PMID 12368481 DOI: 10.1073/Pnas.172521999  0.561
2002 Kimura K, Kakimi K, Wieland S, Guidotti LG, Chisari FV. Interleukin-18 inhibits hepatitis B virus replication in the livers of transgenic mice. Journal of Virology. 76: 10702-7. PMID 12368312 DOI: 10.1128/Jvi.76.21.10702-10707.2002  0.482
2002 Su AI, Guidotti LG, Pezacki JP, Chisari FV, Schultz PG. Gene expression during the priming phase of liver regeneration after partial hepatectomy in mice. Proceedings of the National Academy of Sciences of the United States of America. 99: 11181-6. PMID 12177410 DOI: 10.1073/Pnas.122359899  0.507
2002 Kakimi K, Isogawa M, Chung J, Sette A, Chisari FV. Immunogenicity and tolerogenicity of hepatitis B virus structural and nonstructural proteins: implications for immunotherapy of persistent viral infections. Journal of Virology. 76: 8609-20. PMID 12163580 DOI: 10.1128/Jvi.76.17.8609-8620.2002  0.594
2002 Pasquetto V, Wieland SF, Uprichard SL, Tripodi M, Chisari FV. Cytokine-sensitive replication of hepatitis B virus in immortalized mouse hepatocyte cultures. Journal of Virology. 76: 5646-53. PMID 11991993 DOI: 10.1128/Jvi.76.11.5646-5653.2002  0.472
2002 Robek MD, Wieland SF, Chisari FV. Inhibition of hepatitis B virus replication by interferon requires proteasome activity. Journal of Virology. 76: 3570-4. PMID 11884582 DOI: 10.1128/Jvi.76.7.3570-3574.2002  0.507
2002 Guidotti LG, Morris A, Mendez H, Koch R, Silverman RH, Williams BR, Chisari FV. Interferon-regulated pathways that control hepatitis B virus replication in transgenic mice. Journal of Virology. 76: 2617-21. PMID 11861827 DOI: 10.1128/Jvi.76.6.2617-2621.2002  0.468
2002 Mosier DE, Chisari FV. GB virus C and mortality from HIV infection. The New England Journal of Medicine. 346: 377-9. PMID 11821521 DOI: 10.1056/Nejm200201313460518  0.331
2001 Kakimi K, Lane TE, Wieland S, Asensio VC, Campbell IL, Chisari FV, Guidotti LG. Blocking chemokine responsive to gamma-2/interferon (IFN)-gamma inducible protein and monokine induced by IFN-gamma activity in vivo reduces the pathogenetic but not the antiviral potential of hepatitis B virus-specific cytotoxic T lymphocytes. The Journal of Experimental Medicine. 194: 1755-66. PMID 11748277 DOI: 10.1084/Jem.194.12.1755  0.548
2001 Kakimi K, Lane TE, Chisari FV, Guidotti LG. Cutting edge: Inhibition of hepatitis B virus replication by activated NK T cells does not require inflammatory cell recruitment to the liver Journal of Immunology. 167: 6701-6705. PMID 11739482 DOI: 10.4049/Jimmunol.167.12.6701  0.492
2001 Thimme R, Oldach D, Chang KM, Steiger C, Ray SC, Chisari FV. Determinants of viral clearance and persistence during acute hepatitis C virus infection Journal of Experimental Medicine. 194: 1395-1406. PMID 11714747 DOI: 10.1084/Jem.194.10.1395  0.523
2001 Heise T, Guidotti LG, Chisari FV. Characterization of nuclear RNases that cleave hepatitis B virus RNA near the La protein binding site Journal of Virology. 75: 6874-6883. PMID 11435567 DOI: 10.1128/Jvi.75.15.6874-6883.2001  0.474
2001 Thimme R, Chang KM, Pemberton J, Sette A, Chisari FV. Degenerate immunogenicity of an HLA-A2-restricted hepatitis B virus nucleocapsid cytotoxic T-lymphocyte epitope that is also presented by HLA-B51 Journal of Virology. 75: 3984-3987. PMID 11264388 DOI: 10.1128/Jvi.75.8.3984-3987.2001  0.463
2001 Guidotti LG, Chisari FV. Noncytolytic control of viral infections by the innate and adaptive immune response Annual Review of Immunology. 19: 65-91. PMID 11244031 DOI: 10.1146/Annurev.Immunol.19.1.65  0.479
2001 Schirmbeck R, Zheng X, Roggendorf M, Geissler M, Chisari FV, Reimann J, Lu M. Targeting murine immune responses to selected T cell- or antibody-defined determinants of the hepatitis B surface antigen by plasmid DNA vaccines encoding chimeric antigen Journal of Immunology. 166: 1405-1413. PMID 11145726 DOI: 10.4049/Jimmunol.166.2.1405  0.452
2001 Sette AD, Oseroff C, Sidney J, Alexander J, Chesnut RW, Kakimi K, Guidotti LG, Chisari FV. Overcoming T cell tolerance to the hepatitis B virus surface antigen in hepatitis B virus-transgenic mice Journal of Immunology. 166: 1389-1397. PMID 11145724 DOI: 10.4049/Jimmunol.166.2.1389  0.604
2001 Chang KM, Thimme R, Melpolder JJ, Oldach D, Pemberton J, Moorhead-Loudis J, McHutchison JG, Alter HJ, Chisari FV. Differential CD4+ and CD8+ T-cell responsiveness in hepatitis C virus infection Hepatology. 33: 267-276. PMID 11124845 DOI: 10.1053/Jhep.2001.21162  0.457
2000 Forns X, Thimme R, Govindarajan S, Emerson SU, Purcell RH, Chisari FV, Bukh J. Hepatitis C virus lacking the hypervariable region 1 of the second envelope protein is infectious and causes acute resolving or persistent infection in chimpanzees. Proceedings of the National Academy of Sciences of the United States of America. 97: 13318-23. PMID 11078521 DOI: 10.1073/Pnas.230453597  0.54
2000 McKinney DM, Erickson AL, Walker CM, Thimme R, Chisari FV, Sidney J, Sette A. Identification of five different Patr class I molecules that bind HLA supertype peptides and definition of their peptide binding motifs Journal of Immunology. 165: 4414-4422. PMID 11035079 DOI: 10.4049/Jimmunol.165.8.4414  0.339
2000 Kakimi K, Guidotti LG, Koezuka Y, Chisari FV. Natural killer T cell activation inhibits hepatitis B virus replication in vivo Journal of Experimental Medicine. 192: 921-930. PMID 11015434 DOI: 10.1084/Jem.192.7.921  0.541
2000 Pasquetto V, Wieland S, Chisari FV. Intracellular hepatitis B virus nucleocapsids survive cytotoxic T-lymphocyte-induced apoptosis. Journal of Virology. 74: 9792-6. PMID 11000256 DOI: 10.1128/Jvi.74.20.9792-9796.2000  0.584
2000 Pasquetto V, Guidotti LG, Kakimi K, Tsuji M, Chisari FV. Host-virus interactions during malaria infection in hepatitis B virus transgenic mice Journal of Experimental Medicine. 192: 529-535. PMID 10952722 DOI: 10.1084/Jem.192.4.529  0.588
2000 Voehringer D, Blaser C, Grawitz AB, Chisari FV, Buerki K, Pircher H. Break of T cell ignorance to a viral antigen in the liver induces hepatitis Journal of Immunology. 165: 2415-2422. PMID 10946266 DOI: 10.4049/Jimmunol.165.5.2415  0.469
2000 Guidotti LG, Chisari FV. Cytokine-mediated control of viral infections Virology. 273: 221-227. PMID 10915592 DOI: 10.1006/Viro.2000.0442  0.391
2000 McClary H, Koch R, Chisari FV, Guidotti LG. Inhibition of hepatitis B virus replication during Schistosoma mansoni infection in transgenic mice Journal of Experimental Medicine. 192: 289-294. PMID 10899915 DOI: 10.1084/Jem.192.2.289  0.514
2000 Wieland SF, Guidotti LG, Chisari FV. Intrahepatic induction of alpha/beta interferon eliminates viral RNA-containing capsids in hepatitis B virus transgenic mice. Journal of Virology. 74: 4165-73. PMID 10756029 DOI: 10.1128/Jvi.74.9.4165-4173.2000  0.508
2000 Schirmbeck R, Wild J, Stober D, Blum HE, Chisari FV, Geissler M, Reimann J. Ongoing murine T1 or T2 immune responses to the hepatitis B surface antigen are excluded from the liver that expresses transgene-encoded hepatitis B surface antigen Journal of Immunology. 164: 4235-4243. PMID 10754320 DOI: 10.4049/Jimmunol.164.8.4235  0.483
2000 Chisari FV. Rous-Whipple Award Lecture. Viruses, immunity, and cancer: lessons from hepatitis B American Journal of Pathology. 156: 1117-1132. PMID 10751335 DOI: 10.1016/S0002-9440(10)64980-2  0.529
2000 Guidotti LG, McClary H, Loudis JM, Chisari FV. Nitric oxide inhibits hepatitis B virus replication in the livers of transgenic mice Journal of Experimental Medicine. 191: 1247-1252. PMID 10748242 DOI: 10.1084/Jem.191.7.1247  0.505
2000 Mcclary H, Koch R, Chisari FV, Guidotti LG. Relative sensitivity of hepatitis B virus and other hepatotropic viruses to the antiviral effects of cytokines Journal of Virology. 74: 2255-2264. PMID 10666256 DOI: 10.1128/Jvi.74.5.2255-2264.2000  0.526
2000 Chisari FV. Viruses, immunity, and cancer: Lessons from hepatitis B American Journal of Pathology. 156: 1118-1132.  0.469
1999 Rehermann B, Chisari FV. Cell mediated immune response to the hepatitis C virus. Current Topics in Microbiology and Immunology. 242: 299-325. PMID 10592666 DOI: 10.1007/978-3-642-59605-6_14  0.556
1999 Reifenberg K, Wilts H, Löhler J, Nusser P, Hanano R, Guidotti LG, Chisari FV, Schlicht HJ. The hepatitis B virus X protein transactivates viral core gene expression in vivo Journal of Virology. 73: 10399-10405. PMID 10559358 DOI: 10.1128/Jvi.73.12.10399-10405.1999  0.373
1999 Lauvau G, Kakimi K, Niedermann G, Ostankovitch M, Yotnda P, Firat H, Chisari FV, Van Endert PM. Human transporters associated with antigen processing (TAPs) select epitope precursor peptides for processing in the endoplasmic reticulum and presentation to T cells Journal of Experimental Medicine. 190: 1227-1239. PMID 10544195 DOI: 10.1084/Jem.190.9.1227  0.325
1999 Guidotti LG, Chisari FV. Cytokine-induced viral purging - Role in viral pathogenesis Current Opinion in Microbiology. 2: 388-391. PMID 10490351 DOI: 10.1016/S1369-5274(99)80068-X  0.48
1999 Cerny A, Chisari FV. Pathogenesis of chronic hepatitis C: Immunological features of hepatic injury and viral persistence Hepatology. 30: 595-601. PMID 10462362 DOI: 10.1002/hep.510300312  0.49
1999 Heise T, Guidotti LG, Chisari FV. La autoantigen specifically recognizes a predicted stem-loop in hepatitis B virus RNA Journal of Virology. 73: 5767-5776. PMID 10364328 DOI: 10.1128/Jvi.73.7.5767-5776.1999  0.373
1999 Schultz U, Summers J, Staeheli P, Chisari FV. Elimination of duck hepatitis B virus RNA-containing capsids in duck interferon-alpha-treated hepatocytes Journal of Virology. 73: 5459-5465. PMID 10364293 DOI: 10.1128/Jvi.73.7.5459-5465.1999  0.505
1999 Guidotti LG, Borrow P, Brown A, McClary H, Koch R, Chisari FV. Noncytopathic clearance of lymphocytic choriomeningitis virus from the hepatocyte Journal of Experimental Medicine. 189: 1555-1564. PMID 10330434 DOI: 10.1084/Jem.189.10.1555  0.584
1999 Guidotti LG, Rochford R, Chung J, Shapiro M, Purcell R, Chisari FV. Viral clearance without destruction of infected cells during acute HBV infection Science. 284: 825-829. PMID 10221919 DOI: 10.1126/Science.284.5415.825  0.568
1999 Chemin I, Ohgaki H, Chisari FV, Wild CP. Altered expression of hepatic carcinogen metabolizing enzymes with liver injury in HBV transgenic mouse lineages expressing various amounts of hepatitis B surface antigen. Liver. 19: 81-7. PMID 10220736 DOI: 10.1111/J.1478-3231.1999.Tb00015.X  0.497
1999 Schultz U, Chisari FV. Recombinant duck interferon gamma inhibits duck hepatitis B virus replication in primary hepatocytes Journal of Virology. 73: 3162-3168. PMID 10074168 DOI: 10.1128/Jvi.73.4.3162-3168.1999  0.532
1999 Livingston BD, Alexander J, Crimi C, Oseroff C, Celis E, Daly K, Guidotti LG, Chisari FV, Fikes J, Chesnut RW, Sette A. Altered helper T lymphocyte function associated with chronic hepatitis B virus infection and its role in response to therapeutic vaccination in humans Journal of Immunology. 162: 3088-3095. PMID 10072562  0.429
1999 Chang KM, Gruener NH, Southwood S, Sidney J, Pape GR, Chisari FV, Sette A. Identification of HLA-A3 and -B7-restricted CTL response to hepatitis C virus in patients with acute and chronic hepatitis C Journal of Immunology. 162: 1156-1164. PMID 9916747  0.361
1999 Heise T, Guidotti LG, Cavanaugh VJ, Chisari FV. Hepatitis B virus RNA-binding proteins associated with cytokine-induced clearance of viral RNA from the liver of transgenic mice Journal of Virology. 73: 474-481. PMID 9847353 DOI: 10.1128/Jvi.73.1.474-481.1999  0.448
1998 Alexander J, Fikes J, Hoffman S, Franke E, Sacci J, Appella E, Chisari FV, Guidotti LG, Chesnut RW, Livingston B, Sette A. The optimization of helper T lymphocyte (HTL) function in vaccine development Immunologic Research. 18: 79-92. PMID 9844827 DOI: 10.1007/Bf02788751  0.365
1998 Ishikawa T, Kono D, Chung J, Fowler P, Theofilopoulos A, Kakumu S, Chisari FV. Polyclonality and multispecificity of the CTL response to a single viral epitope Journal of Immunology. 161: 5842-5850. PMID 9834062  0.384
1998 Alexander J, Del Guercio MF, Fikes JD, Chesnut RW, Chisari FV, Chang KM, Appella E, Sette A. Recognition of a novel naturally processed, A2 restricted, HCV-NS4 epitope triggers IFN-gamma release in absence of detectable cytopathicity Human Immunology. 59: 776-782. PMID 9831133 DOI: 10.1016/S0198-8859(98)00080-9  0.395
1998 Shimizu Y, Guidotti LG, Fowler P, Chisari FV. Dendritic cell immunization breaks cytotoxic T lymphocyte tolerance in hepatitis B virus transgenic mice Journal of Immunology. 161: 4520-4529. PMID 9794377  0.424
1998 Lemon SM, Chisari FV, Lai MMC, Nishioka K, Mishiro S, Johnson L. The nineteenth United States-Japan Joint Hepatitis Panel Meeting Hepatology. 28: 881-887. PMID 9731586 DOI: 10.1002/Hep.510280340  0.495
1998 Nakamoto Y, Guidotti LG, Kuhlen CV, Fowler P, Chisari FV. Immune pathogenesis of hepatocellular carcinoma Journal of Experimental Medicine. 188: 341-350. PMID 9670046 DOI: 10.1084/Jem.188.2.341  0.473
1998 Cavanaugh VJ, Guidotti LG, Chisari FV. Inhibition of hepatitis B virus replication during adenovirus and cytomegalovirus infections in transgenic mice Journal of Virology. 72: 2630-2637. PMID 9525579 DOI: 10.1128/Jvi.72.4.2630-2637.1998  0.592
1998 Chisari FV. Intracellular Inactivation of the Hepatitis B Virus by Inflammatory Cytokines Kanzo. 39: 57-57. DOI: 10.2957/Kanzo.39.Supl2_57  0.504
1997 Hu JF, Cheng Z, Chisari FV, Vu TH, Hoffman AR, Campbell TC. Repression of hepatitis B virus (HBV) transgene and HBV-induced liver injury by low protein diet Oncogene. 15: 2795-2801. PMID 9419970  0.385
1997 Chang KM, Rehermann B, McHutchison JG, Pasquinelli C, Southwood S, Sette A, Chisari FV. Immunological significance of cytotoxic T lymphocyte epitope variants in patients chronically infected by the hepatitis C virus Journal of Clinical Investigation. 100: 2376-2385. PMID 9410918 DOI: 10.1172/Jci119778  0.498
1997 Jakubczak JL, Chisari FV, Merlino G. Synergy between transforming growth factor α and hepatitis B virus surface antigen in hepatocellular proliferation and carcinogenesis Cancer Research. 57: 3606-3611. PMID 9270035  0.377
1997 Chang KM, Rehermann B, Chisari FV. Immunopathology of hepatitis C Springer Seminars in Immunopathology. 19: 57-68. PMID 9266631 DOI: 10.1007/Bf00945025  0.576
1997 Kuhröber A, Wild J, Pudollek HP, Chisari FV, Reimann J. DNA vaccination with plasmids encoding the intracellular (HBcAg) or secreted (HBeAg) form of the core protein of hepatitis B virus primes T cell responses to two overlapping Kb- and K(d)-restricted epitopes International Immunology. 9: 1203-1212. PMID 9263018 DOI: 10.1093/Intimm/9.8.1203  0.43
1997 Franco A, Guidotti LG, Hobbs MV, Pasquetto V, Chisari FV. Pathogenetic Effector Function of CD4-Positive T Helper 1 Cells in Hepatitis B Virus Transgenic Mice Journal of Immunology. 159: 2001-2008. PMID 9257867  0.498
1997 Bertoni R, Sidney J, Fowler P, Chesnut RW, Chisari FV, Sette A. Human histocompatibility leukocyte antigen-binding supermotifs predict broadly cross-reactive cytotoxic T lymphocyte responses in patients with acute hepatitis Journal of Clinical Investigation. 100: 503-513. PMID 9239396 DOI: 10.1172/Jci119559  0.449
1997 Livingston BD, Crimi C, Grey H, Ishioka G, Chisari FV, Fikes J, Chesnut RW, Sette A. The Hepatitis B Virus-Specific CTL Responses Induced in Humans by Lipopeptide Vaccination Are Comparable to Those Elicited by Acute Viral Infection Journal of Immunology. 159: 1383-1392. PMID 9233635  0.363
1997 Nakamoto Y, Guidotti LG, Pasquetto V, Schreiber RD, Chisari FV. Differential Target Cell Sensitivity to CTL-Activated Death Pathways In Hepatitis B Virus Transgenic Mice Journal of Immunology. 158: 5692-5697. PMID 9190918  0.404
1997 Guidotti LG, Matzke B, Chisari FV. Hepatitis B virus replication is cell cycle independent during liver regeneration in transgenic mice Journal of Virology. 71: 4804-4808. PMID 9151875 DOI: 10.1128/Jvi.71.6.4804-4808.1997  0.553
1997 Kaplanski C, Chisari FV, Wild CP. Minisatellite rearrangements are increased in liver tumours induced by transplacental aflatoxin B1 treatment of hepatitis B virus transgenic mice, but not in spontaneously arising tumours Carcinogenesis. 18: 633-639. PMID 9111192 DOI: 10.1093/Carcin/18.4.633  0.457
1997 Cavanaugh VJ, Guidotti LG, Chisari FV. Interleukin-12 inhibits hepatitis B virus replication in transgenic mice Journal of Virology. 71: 3236-3243. PMID 9060687 DOI: 10.1128/Jvi.71.4.3236-3243.1997  0.463
1997 Pasquinelli C, Shoenberger JM, Chung J, Chang KMI, Guidotti LG, Selby M, Berger K, Lesniewski R, Houghton M, Chisari FV. Hepatitis C virus core and E2 protein expression in transgenic mice Hepatology. 25: 719-727. PMID 9049225 DOI: 10.1002/Hep.510250338  0.51
1997 Chisari FV. Cytotoxic T cells and viral hepatitis Journal of Clinical Investigation. 100.  0.426
1996 Rehermann B, Ferrari C, Pasquinelli C, Chisari FV. The hepatitis B virus persists for decades after patients' recovery from acute viral hepatitis despite active maintenance of a cytotoxic T-lymphocyte response Nature Medicine. 2: 1104-1108. PMID 8837608 DOI: 10.1038/Nm1096-1104  0.574
1996 Rehermann B, Chang KM, McHutchison JG, Kokka R, Houghton M, Chisari FV. Quantitative analysis of the peripheral blood cytotoxic T lymphocyte response in patients with chronic hepatitis C virus infection Journal of Clinical Investigation. 98: 1432-1440. PMID 8823309 DOI: 10.1172/Jci118931  0.522
1996 Rehermann B, Chang KM, McHutchison J, Kokka R, Houghton M, Rice CM, Chisari FV. Differential cytotoxic T-lymphocyte responsiveness to the hepatitis B and C viruses in chronically infected patients Journal of Virology. 70: 7092-7102. PMID 8794355 DOI: 10.1128/Jvi.70.10.7092-7102.1996  0.522
1996 Guidotti LG, Matzke B, Pasquinelli C, Shoenberger JM, Rogler CE, Chisari FV. The hepatitis B virus (HBV) precore protein inhibits HBV replication in transgenic mice? Journal of Virology. 70: 7056-7061. PMID 8794350 DOI: 10.1128/Jvi.70.10.7056-7061.1996  0.552
1996 Guidotti LG, Chisari FV. To kill or to cure: Options in host defense against viral infection Current Opinion in Immunology. 8: 478-483. PMID 8794011 DOI: 10.1016/S0952-7915(96)80034-3  0.586
1996 Penna A, Artini M, Cavalli A, Levrero M, Bertoletti A, Pilli M, Chisari FV, Rehermann B, Del Prete G, Fiaccadori F, Ferrari C. Long-lasting memory T cell responses following self-limited acute hepatitis B. The Journal of Clinical Investigation. 98: 1185-94. PMID 8787682 DOI: 10.1172/Jci118902  0.537
1996 Chemin I, Takahashi S, Belloc C, Lang MA, Ando K, Guidotti LG, Chisari FV, Wild CP. Differential induction of carcinogen metabolizing enzymes in a transgenic mouse model of fulminant hepatitis Hepatology. 24: 649-656. PMID 8781338 DOI: 10.1002/Hep.510240330  0.461
1996 Wentworth PA, Sette A, Celis E, Sidney J, Southwood S, Crimi C, Stitely S, Keogh E, Wong NC, Livingston B, Alazard D, Vitiello A, Grey HM, Chisari FV, Chesnut RW, et al. Identification of A2-restricted hepatitis C virus-specific cytotoxic T lymphocyte epitopes from conserved regions of the viral genome. International Immunology. 8: 651-9. PMID 8671652 DOI: 10.1093/Intimm/8.5.651  0.389
1996 Fernandes CL, Dong JH, Roebuck BD, Chisari FV, Montali JA, Schmidt DE, Prochaska HJ. Elevations of hepatic quinone reductase, glutathione, and α- and μ- class glutathione S-transferase isoforms in mice with chronic hepatitis: A compensatory response to injury Archives of Biochemistry and Biophysics. 331: 104-116. PMID 8660689 DOI: 10.1006/Abbi.1996.0288  0.406
1996 Guidotti LG, Borrow P, Hobbs MV, Matzke B, Gresser I, Oldstone MB, Chisari FV. Viral cross talk: intracellular inactivation of the hepatitis B virus during an unrelated viral infection of the liver. Proceedings of the National Academy of Sciences of the United States of America. 93: 4589-94. PMID 8643448 DOI: 10.1073/Pnas.93.10.4589  0.578
1996 Kuhöber A, Pudollek HP, Reifenberg K, Chisari FV, Schlicht HJ, Reimann J, Schirmbeck R. DNA immunization induces antibody and cytotoxic T cell responses to hepatitis B core antigen in H-2b mice Journal of Immunology. 156: 3687-3695. PMID 8621903  0.31
1996 Chisari FV. Hepatitis B virus transgenic mice: Models of viral immunobiology and pathogenesis Current Topics in Microbiology and Immunology. 206: 148-173. PMID 8608715 DOI: 10.1007/978-3-642-85208-4_9  0.525
1996 Rehermann B, Lau D, Hoofnagle JH, Chisari FV. Cytotoxic T lymphocyte responsiveness after resolution of chronic hepatitis B virus infection Journal of Clinical Investigation. 97: 1655-1665. PMID 8601631 DOI: 10.1172/Jci118592  0.578
1996 Guidotti LG, Ishikawa T, Hobbs MV, Matzke B, Schreiber R, Chisari FV. Intracellular inactivation of the hepatitis B virus by cytotoxic T lymphocytes Immunity. 4: 25-36. PMID 8574849 DOI: 10.1016/S1074-7613(00)80295-2  0.573
1996 Ferrari C, Bertoletti A, Fiaccadori F, Chisari FV. Is antigenic variability a strategy adopted by hepatitis B virus to escape cytotoxic T-lymphocyte surveillance? Seminars in Virology. 7: 23-30. DOI: 10.1006/Smvy.1996.0004  0.519
1996 Guidotti LG, Chisari FV. The transgenic mouse model of hepatitis B virus infection Forum - Trends in Experimental and Clinical Medicine. 6: 189-200.  0.51
1995 Tsui LV, Guidotti LG, Ishikawa T, Chisari FV. Posttranscriptional clearance of hepatitis B virus RNA by cytotoxic T lymphocyte-activated hepatocytes Proceedings of the National Academy of Sciences of the United States of America. 92: 12398-12402. PMID 8618909 DOI: 10.1073/Pnas.92.26.12398  0.558
1995 Chisari FV, Ferrari C. Hepatitis B virus immunopathology Springer Seminars in Immunopathology. 17: 261-281. PMID 8571172 DOI: 10.1007/Bf00196169  0.592
1995 Huang SN, Chisari FV. Strong, sustained hepatocellular proliferation precedes hepatocarcinogenesis in hepatitis B surface antigen transgenic mice. Hepatology (Baltimore, Md.). 21: 620-6. PMID 7875658 DOI: 10.1002/Hep.1840210303  0.468
1995 Cerny A, Fowler P, Brothers MA, Houghton M, Schlicht HJ, Chisari FV. Induction in vitro of a primary human antiviral cytotoxic T cell response. European Journal of Immunology. 25: 627-30. PMID 7875224 DOI: 10.1002/Eji.1830250248  0.468
1995 Wirth S, Guidotti LG, Ando K, Schlicht HJ, Chisari FV. Breaking tolerance leads to autoantibody production but not autoimmune liver disease in hepatitis B virus envelope transgenic mice Journal of Immunology. 154: 2504-2515. PMID 7868916  0.479
1995 Cerny A, McHutchison JG, Pasquinelli C, Brown ME, Brothers MA, Grabscheid B, Fowler P, Houghton M, Chisari FV. Cytotoxic T lymphocyte response to hepatitis C virus-derived peptides containing the HLA A2.1 binding motif. The Journal of Clinical Investigation. 95: 521-30. PMID 7860734 DOI: 10.1172/Jci117694  0.506
1995 Vitiello A, Ishioka G, Grey HM, Rose R, Farness P, LaFond R, Yuan L, Chisari FV, Furze J, Bartholomeuz R. Development of a lipopeptide-based therapeutic vaccine to treat chronic HBV infection. I. Induction of a primary cytotoxic T lymphocyte response in humans. The Journal of Clinical Investigation. 95: 341-9. PMID 7814635 DOI: 10.1172/Jci117662  0.412
1995 Guidotti LG, Matzke B, Schaller H, Chisari FV. High-level hepatitis B virus replication in transgenic mice Journal of Virology. 69: 6158-6169. PMID 7666518 DOI: 10.1128/Jvi.69.10.6158-6169.1995  0.546
1995 Schirmbeck R, Bohm W, Ando K, Chisari FV, Reimann J. Nucleic acid vaccination primes hepatitis B virus surface antigen-specific cytotoxic T lymphocytes in nonresponder mice Journal of Virology. 69: 5929-5934. PMID 7666497 DOI: 10.1128/Jvi.69.10.5929-5934.1995  0.475
1995 Wentworth PA, Celis E, Crimi C, Stitely S, Hale L, Tsai V, Serra HM, Del Guercio MF, Livingston B, Alazard D, Fikes J, Kubo RT, Grey HM, Chesnut RW, Chisari FV, et al. In vitro induction of primary, antigen-specific CTL from human peripheral blood mononuclear cells stimulated with synthetic peptides. Molecular Immunology. 32: 603-12. PMID 7643853 DOI: 10.1016/0161-5890(95)00037-F  0.354
1995 Chisari FV, Ferrari C. Hepatitis B virus immunopathogenesis Annual Review of Immunology. 13: 29-60. PMID 7612225 DOI: 10.1146/Annurev.Iy.13.040195.000333  0.59
1995 Chisari FV. Hepatitis B virus transgenic mice: Insights into the virus and the disease Hepatology. 22: 1316-1325. PMID 7557887 DOI: 10.1002/Hep.1840220443  0.555
1995 Rehermann B, Pasquinelli C, Mosier SM, Chisari FV. Hepatitis B virus (HBV) sequence variation in cytotoxic T lymphocyte epitopes is not common in patients with chronic HBV infection Journal of Clinical Investigation. 96: 1527-1534. PMID 7544809 DOI: 10.1172/Jci118191  0.579
1995 Rehermann B, Fowler P, Sidney J, Person J, Redeker A, Brown M, Moss B, Sette A, Chisari FV. The cytotoxic T lymphocyte response to multiple hepatitis B virus polymerase epitopes during and after acute viral hepatitis Journal of Experimental Medicine. 181: 1047-1058. PMID 7532675 DOI: 10.1084/Jem.181.3.1047  0.571
1995 Franco A, Ferrari C, Sette A, Chisari FV. Viral mutations, TCR antagonism and escape from the immune response Current Opinion in Immunology. 7: 524-531. PMID 7495517 DOI: 10.1016/0952-7915(95)80098-0  0.341
1995 Lanford RE, Chavez D, Chisari FV, Sureau C. Lack of detection of negative-strand hepatitis C virus RNA in peripheral blood mononuclear cells and other extrahepatic tissues by the highly strand-specific rTth reverse transcriptase PCR Journal of Virology. 69: 8079-8083. PMID 7494326 DOI: 10.1128/Jvi.69.12.8079-8083.1995  0.443
1994 Guilhot S, Huang SN, Xia YP, La Monica N, Lai MM, Chisari FV. Expression of the hepatitis delta virus large and small antigens in transgenic mice. Journal of Virology. 68: 1052-8. PMID 8289334 DOI: 10.1128/Jvi.68.2.1052-1058.1994  0.589
1994 Michalak TI, Pasquinelli C, Guilhot S, Chisari FV. Hepatitis B virus persistence after recovery from acute viral hepatitis. The Journal of Clinical Investigation. 93: 230-9. PMID 8282792 DOI: 10.1172/Jci116950  0.553
1994 Bertoletti A, Sette A, Chisari FV, Penna A, Levrero M, De Carli M, Fiaccadori F, Ferrari C. Natural variants of cytotoxic epitopes are T-cell receptor antagonists for antiviral cytotoxic T cells. Nature. 369: 407-10. PMID 8196768 DOI: 10.1038/369407A0  0.468
1994 Guidotti LG, Ando K, Hobbs MV, Ishikawa T, Runkel L, Schreiberu RD, Chisari FV. Cytotoxic T lymphocytes inhibit hepatitis B virus gene expression by a noncytolytic mechanism in transgenic mice Proceedings of the National Academy of Sciences of the United States of America. 91: 3764-3768. PMID 8170985 DOI: 10.1073/Pnas.91.9.3764  0.595
1994 Ando K, Guidotti LG, Wirth S, Ishikawa T, Missale G, Moriyama T, Schreiber RD, Schlicht HJ, Huang SN, Chisari FV. Class I-restricted cytotoxic T lymphocytes are directly cytopathic for their target cells in vivo. Journal of Immunology (Baltimore, Md. : 1950). 152: 3245-53. PMID 8144915  0.316
1994 Guidotti LG, Guilhot S, Chisari FV. Interleukin-2 and alpha/beta interferon down-regulate hepatitis B virus gene expression in vivo by tumor necrosis factor-dependent and -independent pathways Journal of Virology. 68: 1265-1270. PMID 8107192 DOI: 10.1128/Jvi.68.3.1265-1270.1994  0.441
1994 Guidotti LG, Martinez V, Loh YT, Rogler CE, Chisari FV. Hepatitis B virus nucleocapsid particles do not cross the hepatocyte nuclear membrane in transgenic mice Journal of Virology. 68: 5469-5475. PMID 8057429 DOI: 10.1128/Jvi.68.9.5469-5475.1994  0.374
1994 Michalak TI, Pasquinelli C, Guilhot S, Chisari FV. Hepatitis B virus persistence after recovery from acute viral hepatitis Journal of Clinical Investigation. 94: 907. PMID 8040346  0.47
1994 Toshkov I, Chisari FV, Bannasch P. Hepatic preneoplasia in hepatitis B virus transgenic mice Hepatology. 20: 1162-1172. PMID 7927248 DOI: 10.1002/Hep.1840200510  0.473
1994 Kirby G, Chemin I, Montesano R, Chisari FV, Lang MA, Wild CP. Induction of specific cytochrome p450s involved in aflatoxin B1 metabolism in hepatitis B virus transgenic mice Molecular Carcinogenesis. 11: 74-80. PMID 7916995 DOI: 10.1002/Mc.2940110204  0.489
1994 Cerny A, Chisari FV. Immunological aspects of HCV infection Intervirology. 37: 119-125. PMID 7814241 DOI: 10.1159/000150366  0.503
1994 Hagen TM, Huang S, Curnutte J, Fowler P, Martinez V, Wehr CM, Ames BN, Chisari FV. Extensive oxidative DNA damage in hepatocytes of transgenic mice with chronic active hepatitis destined to develop hepatocellular carcinoma Proceedings of the National Academy of Sciences of the United States of America. 91: 12808-12812. PMID 7809125 DOI: 10.1073/Pnas.91.26.12808  0.457
1994 Huang JH, Getty RR, Chisari FV, Fowler P, Greenspan NS, Tykocinski ML. Protein transfer of preformed MHC-peptide complexes sensitizes target cells to T cell cytolysis Immunity. 1: 607-613. PMID 7600289 DOI: 10.1016/1074-7613(94)90050-7  0.375
1994 Cerny A, Ferrari C, Chisari FV. The class I-restricted cytotoxic T lymphocyte response to predetermined epitopes in the hepatitis B and C viruses Current Topics in Microbiology and Immunology. 189: 169-186. PMID 7523032 DOI: 10.1007/978-3-642-78530-6_10  0.496
1994 Bertoletti A, Costanzo A, Chisari FV, Levrero M, Artini M, Sette A, Penna A, Giuberti T, Fiaccadori F, Ferrari C. Cytotoxic T lymphocyte response to a wild type hepatitis B virus epitope in patients chronically infected by variant viruses carrying substitutions within the epitope. The Journal of Experimental Medicine. 180: 933-43. PMID 7520476 DOI: 10.1084/Jem.180.3.933  0.554
1993 Chisari FV. The role of cytotoxic T lymphocytes and inflammatory cytokines in the pathogenesis of acute viral hepatitis. Gastroenterologia Japonica. 2-6; discussion 17-9. PMID 8486226 DOI: 10.1007/Bf02782879  0.547
1993 Guilhot S, Guidotti LG, Chisari FV. Interleukin-2 downregulates hepatitis B virus gene expression in transgenic mice by a posttranscriptional mechanism. Journal of Virology. 67: 7444-9. PMID 8230465 DOI: 10.1128/Jvi.67.12.7444-7449.1993  0.45
1993 Ando K, Moriyama T, Guidotti LG, Wirth S, Schreiber RD, Schlicht HJ, Huang SN, Chisari FV. Mechanisms of class I restricted immunopathology. A transgenic mouse model of fulminant hepatitis. The Journal of Experimental Medicine. 178: 1541-54. PMID 8228807 DOI: 10.1084/Jem.178.5.1541  0.556
1993 Bertoletti A, Chisari FV, Penna A, Guilhot S, Galati L, Missale G, Fowler P, Schlicht HJ, Vitiello A, Chesnut RC. Definition of a minimal optimal cytotoxic T-cell epitope within the hepatitis B virus nucleocapsid protein. Journal of Virology. 67: 2376-80. PMID 7680391 DOI: 10.1128/Jvi.67.4.2376-2380.1993  0.531
1993 Missale G, Redeker A, Person J, Fowler P, Guilhot S, Schlicht HJ, Ferrari C, Chisari FV. HLA-A31- and HLA-Aw68-restricted cytotoxic T cell responses to a single hepatitis B virus nucleocapsid epitope during acute viral hepatitis. The Journal of Experimental Medicine. 177: 751-62. PMID 7679709 DOI: 10.1084/Jem.177.3.751  0.537
1993 Chisari FV. Hepatitis B virus biology and pathogenesis. Molecular Genetic Medicine. 2: 67-104. PMID 1333869 DOI: 10.1016/B978-0-12-462002-5.50008-X  0.541
1993 Missale G, Brems JJ, Takiff H, Pockros PJ, Chisari FV. Human leukocyte antigen class I-independent pathways may contribute to hepatitis B virus-induced liver disease after liver transplantation Hepatology. 18: 491-496. DOI: 10.1002/hep.1840180304  0.378
1992 Penna A, Fowler P, Bertoletti A, Guilhot S, Moss B, Margolskee RF, Cavalli A, Valli A, Fiaccadori F, Chisari FV. Hepatitis B virus (HBV)-specific cytotoxic T-cell (CTL) response in humans: characterization of HLA class II-restricted CTLs that recognize endogenously synthesized HBV envelope antigens. Journal of Virology. 66: 1193-8. PMID 1731098 DOI: 10.1128/Jvi.66.2.1193-1198.1992  0.56
1992 Gilles PN, Fey G, Chisari FV. Tumor necrosis factor alpha negatively regulates hepatitis B virus gene expression in transgenic mice. Journal of Virology. 66: 3955-60. PMID 1583737 DOI: 10.1128/Jvi.66.6.3955-3960.1992  0.465
1992 Gilles PN, Guerrette DL, Ulevitch RJ, Schreiber RD, Chisari FV. HBsAg retention sensitizes the hepatocyte to injury by physiological concentrations of interferon-γ Hepatology. 16: 655-663. PMID 1505908 DOI: 10.1002/Hep.1840160308  0.509
1992 Rogler CE, Chisari FV. Cellular and molecular mechanisms of hepatocarcinogenesis. Seminars in Liver Disease. 12: 265-78. PMID 1439879 DOI: 10.1055/S-2007-1007398  0.344
1992 Guilhot S, Fowler P, Portillo G, Margolskee RF, Ferrari C, Bertoletti A, Chisari FV. Hepatitis B virus (HBV)-specific cytotoxic T-cell response in humans: production of target cells by stable expression of HBV-encoded proteins in immortalized human B-cell lines. Journal of Virology. 66: 2670-8. PMID 1313893 DOI: 10.1128/Jvi.66.5.2670-2678.1992  0.563
1992 Penna A, Fowler P, Bertoletti A, Guilhot S, Moss B, Margolskee RF, Cavalli A, Valli A, Fiaccadori F, Chisari FV. Hepatitis B virus (HBV)-specific cytotoxic T-cell (CTL) response in humans: characterization of HLA class II-restricted CTLs that recognize endogenously synthesized HBV envelope antigens. Journal of Virology. 66: 1193-1198. DOI: 10.1128/jvi.66.2.1193-1198.1992  0.45
1991 Chisari FV. Analysis of hepadnavirus gene expression, biology, and pathogenesis in the transgenic mouse. Current Topics in Microbiology and Immunology. 168: 85-101. PMID 1893780 DOI: 10.1007/978-3-642-76015-0_5  0.536
1991 Penna A, Chisari FV, Bertoletti A, Missale G, Fowler P, Giuberti T, Fiaccadori F, Ferrari C. Cytotoxic T lymphocytes recognize an HLA-A2-restricted epitope within the hepatitis B virus nucleocapsid antigen. The Journal of Experimental Medicine. 174: 1565-70. PMID 1720813 DOI: 10.1084/Jem.174.6.1565  0.589
1991 Ferrari C, Bertoletti A, Penna A, Cavalli A, Valli A, Missale G, Pilli M, Fowler P, Giuberti T, Chisari FV. Identification of immunodominant T cell epitopes of the hepatitis B virus nucleocapsid antigen. The Journal of Clinical Investigation. 88: 214-22. PMID 1711541 DOI: 10.1172/Jci115280  0.409
1991 Bertoletti A, Ferrari C, Fiaccadori F, Penna A, Margolskee R, Schlicht HJ, Fowler P, Guilhot S, Chisari FV. HLA class I-restricted human cytotoxic T cells recognize endogenously synthesized hepatitis B virus nucleocapsid antigen. Proceedings of the National Academy of Sciences of the United States of America. 88: 10445-9. PMID 1660137 DOI: 10.1073/Pnas.88.23.10445  0.59
1991 Toshkov I, Chisari F, Bannasch P. Phenotypic patterns of preneoplastic and neoplastic hepatic lesions in hepatitis B virus transgenic mice European Journal of Cancer and Clinical Oncology. 27: S64. DOI: 10.1016/0277-5379(91)91440-T  0.395
1991 Penna A, Chisari F, Bertoletti A, Missale G, Giuberti T, Marchelli S, Galati L, Fiaccadori F, Ferrari C. Cytotoxic T lymphocytes recognize an HLA-A2 restricted epitope within the hepatitis B virus nucleocapsid antigen Journal of Hepatology. 13: S59. DOI: 10.1016/0168-8278(91)91223-4  0.484
1991 Bertolettl A, Ferrari C, Penna A, Flaccaduri F, Schlicht H, Fowler P, Gullhot S, Chisari F. HLA class I restricted cytotoxic T cells in acute viral hepatitis type B Journal of Hepatology. 13: S11. DOI: 10.1016/0168-8278(91)91031-B  0.485
1991 Peters M, Vierling J, Gershwin ME, Milich D, Chisari FV, Hoofnagle JH. Immunology and the liver Hepatology. 13: 977-994. DOI: 10.1002/Hep.1840130529  0.353
1990 Mondelli MU, Chisari FV, Ferrari C. The cellular immune response to nucleocapsid antigens in hepatitis B virus infection. Springer Seminars in Immunopathology. 12: 25-31. PMID 2195679 DOI: 10.1007/Bf00192679  0.572
1990 Teeter LD, Becker FF, Chisari FV, Li DJ, Kuo MT. Overexpression of the multidrug resistance gene mdr3 in spontaneous and chemically induced mouse hepatocellular carcinomas. Molecular and Cellular Biology. 10: 5728-35. PMID 2122232 DOI: 10.1128/Mcb.10.11.5728  0.334
1990 Moriyama T, Guilhot S, Klopchin K, Moss B, Pinkert CA, Palmiter RD, Brinster RL, Kanagawa O, Chisari FV. Immunobiology and pathogenesis of hepatocellular injury in hepatitis B virus transgenic mice. Science (New York, N.Y.). 248: 361-4. PMID 1691527 DOI: 10.1126/Science.1691527  0.568
1989 Raney AK, Milich DR, Hughes JL, Sorge J, Chisari FV, Mondelli MU, McLachlan A. Retroviral-mediated transfer and expression of hepatitis B e antigen in human primary skin fibroblasts and Epstein-Barr virus-transformed B lymphocytes. Virology. 168: 31-9. PMID 2783354 DOI: 10.1016/0042-6822(89)90400-5  0.515
1989 Chisari FV, Ferrari C, Mondelli MU. Hepatitis B virus structure and biology. Microbial Pathogenesis. 6: 311-25. PMID 2671579 DOI: 10.1016/0882-4010(89)90073-9  0.582
1989 Chisari FV, Klopchin K, Moriyama T, Pasquinelli C, Dunsford HA, Sell S, Pinkert CA, Brinster RL, Palmiter RD. Molecular pathogenesis of hepatocellular carcinoma in hepatitis B virus transgenic mice. Cell. 59: 1145-56. PMID 2598264 DOI: 10.1016/0092-8674(89)90770-8  0.49
1987 McLachlan A, Milich DR, Raney AK, Riggs MG, Hughes JL, Sorge J, Chisari FV. Expression of hepatitis B virus surface and core antigens: influences of pre-S and precore sequences. Journal of Virology. 61: 683-92. PMID 3543403 DOI: 10.1128/Jvi.61.3.683-692.1987  0.436
1987 Chisari FV, Filippi P, Buras J, McLachlan A, Popper H, Pinkert CA, Palmiter RD, Brinster RL. Structural and pathological effects of synthesis of hepatitis B virus large envelope polypeptide in transgenic mice. Proceedings of the National Academy of Sciences of the United States of America. 84: 6909-13. PMID 3477814 DOI: 10.1073/Pnas.84.19.6909  0.536
1986 Chisari FV, Filippi P, McLachlan A, Milich DR, Riggs M, Lee S, Palmiter RD, Pinkert CA, Brinster RL. Expression of hepatitis B virus large envelope polypeptide inhibits hepatitis B surface antigen secretion in transgenic mice. Journal of Virology. 60: 880-7. PMID 3783819 DOI: 10.1128/Jvi.60.3.880-887.1986  0.511
1986 Milich DR, McLachlan A, Chisari FV, Thornton GB. Nonoverlapping T and B cell determinants on an hepatitis B surface antigen pre-S(2) region synthetic peptide. The Journal of Experimental Medicine. 164: 532-47. PMID 2425034 DOI: 10.1084/Jem.164.2.532  0.388
1986 Milich DR, McNamara MK, McLachlan A, Thornton GB, Chisari FV. Distinct H-2-linked regulation of T-cell responses to the pre-S and S regions of the same hepatitis B surface antigen polypeptide allows circumvention of nonresponsiveness to the S region. Proceedings of the National Academy of Sciences of the United States of America. 82: 8168-72. PMID 2415982 DOI: 10.1073/Pnas.82.23.8168  0.366
1985 Chisari FV, Pinkert CA, Milich DR, Filippi P, McLachlan A, Palmiter RD, Brinster RL. A transgenic mouse model of the chronic hepatitis B surface antigen carrier state. Science (New York, N.Y.). 230: 1157-60. PMID 3865369 DOI: 10.1126/Science.3865369  0.522
1985 Milich DR, Thornton GB, Neurath AR, Kent SB, Michel ML, Tiollais P, Chisari FV. Enhanced immunogenicity of the pre-S region of hepatitis B surface antigen. Science (New York, N.Y.). 228: 1195-9. PMID 2408336 DOI: 10.1126/Science.2408336  0.368
1985 Michel M, Pontisso P, Sobzack E, Malpiece Y, Streeck R, Milich D, Chisari F, Tiollais P. Synthesis in cho cells of hepatitis B surface antigen containing the PRE-S2 region expression product Annales De L'Institut Pasteur / Virologie. 136: 495-502. DOI: 10.1016/S0769-2617(85)80142-8  0.419
1984 Milich DR, Leroux-Roels GG, Louie RE, Chisari FV. Genetic regulation of the immune response to hepatitis B surface antigen (HBsAg). IV. Distinct H-2-linked Ir genes control antibody responses to different HBsAg determinants on the same molecule and map to the I-A and I-C subregions. The Journal of Experimental Medicine. 159: 41-56. PMID 6198427 DOI: 10.1084/Jem.159.1.41  0.362
1984 Kasahara Y, Leroux-Roels G, Nakamura R, Chisari F. Glycylprolyl-diaminopeptidase in human leukocytes: selective occurrence in T lymphocytes and influence on the total serum enzyme activity. Clinica Chimica Acta; International Journal of Clinical Chemistry. 139: 295-302. PMID 6146412 DOI: 10.1016/0009-8981(84)90275-4  0.325
1982 Pizzo C, Lee D, Chisari FV. Suppression of lymphocyte activation by a protein released from isolated perfused rat liver. Hepatology (Baltimore, Md.). 2: 295-303. PMID 6978837 DOI: 10.1002/Hep.1840020302  0.361
1982 Levy GA, Chisari FV. A proposed role for the immune system in the pathogenesis of hepatitis B virus induced liver disease. Critical Reviews in Clinical Laboratory Sciences. 15: 335-53. PMID 6459211 DOI: 10.3109/10408368109105874  0.514
1981 Chisari FV, Curtiss LK, Jensen FC. Physiologic concentrations of normal human plasma lipoproteins inhibit the immortalization of peripheral B lymphocytes by the Epstein-Barr virus. The Journal of Clinical Investigation. 68: 329-36. PMID 6267100 DOI: 10.1172/Jci110260  0.345
1981 Levy GA, Chisari FV. The immunopathogenesis of chronic HBV induced liver disease. Springer Seminars in Immunopathology. 3: 439-59. PMID 6168027 DOI: 10.1007/Bf01951492  0.572
1980 Chisari FV. Modulation of the in vivo immune response by human plasma very low-density lipoproteins. Cellular Immunology. 52: 223-8. PMID 7388956 DOI: 10.1016/0008-8749(80)90415-3  0.315
1980 Chisari FV. Liver-specific protein in perspective Gastroenterology. 78: 168-170. DOI: 10.1016/0016-5085(80)90207-3  0.336
1979 ROUTENBERG JA, DIENSTAG JL, HARRISON WO, KILPATRICK ME, HOOPER RR, CHISARI FV, PURCELL RH, FORNES MF. Foodborne outbreak of hepatitis A The American Journal of the Medical Sciences. 278: 123-138. DOI: 10.1097/00000441-197909000-00003  0.483
1978 Knecht GL, Chisari FV. Reversibility of hepatitis B virus-induced glomerulonephritis and chronic active hepatitis after spontaneous clearance of serum hepatitis B surface antigen Gastroenterology. 75: 1152-1156. DOI: 10.1016/0016-5085(78)90092-6  0.514
1977 Chisari FV, Gealy WJ, Edgington TS. Recovery of soluble sheep erythrocyte receptor from the T lymphocyte surface by proteolytic cleavage. Journal of Immunology (Baltimore, Md. : 1950). 118: 1138-42. PMID 300398  0.492
1977 Chisari FV, Routenberg JA, Fiala M, Edgington TS. Extrinsic modulation of human T-lymphocyte E rosette function associated with prolonged hepatocellular injury after viral hepatitis. The Journal of Clinical Investigation. 59: 134-42. PMID 187620 DOI: 10.1172/Jci108610  0.69
1976 Chisari FV, Routenberg JA, Edgington TS. Mechanisms responsible for defective human T-lymphocyte sheep erythrocyte rosette function associated with hepatitis B virus infections. The Journal of Clinical Investigation. 57: 1227-38. PMID 1083396 DOI: 10.1172/Jci108391  0.637
1976 Chisari FV, Edgington TS. Lymphocyte E rosette inhibitory factor: a regulatory serum lipoprotein. The Journal of Experimental Medicine. 142: 1092-1107. PMID 172585 DOI: 10.1084/Jem.142.5.1092  0.618
1975 Chisari FV, Edgington TS. Human T lymphocyte "E" rosette function. I. A process modulated by intracellular cyclic AMP. The Journal of Experimental Medicine. 140: 1122-6. PMID 4372291 DOI: 10.1084/Jem.140.4.1122  0.529
1975 Nakamura RM, Chisari FV, Edgington TS. Laboratory tests for diagnosis of autoimmune diseases. Progress in Clinical Pathology. 6: 177-203. PMID 1105671  0.569
1975 Edgington TS, Chisari FV. Immunological aspects of hepatitis B virus infection. The American Journal of the Medical Sciences. 270: 212-27. PMID 799469  0.663
1974 Chisari FV, Gerin JL, Edgington TS. Immunochemistry of the hepatitis B virus: 125I HB Ag ligand. Journal of Immunology (Baltimore, Md. : 1950). 113: 543-53. PMID 4845665  0.601
1971 Deal DR, Gerber P, Chisari FV. Hetérotransplantation of two human lymphoid cell lines transformed in vitro by epstein-barr virus Journal of the National Cancer Institute. 47: 771-780. PMID 4328947 DOI: 10.1093/Jnci/47.4.771  0.361
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