Michael M. White, PhD - Related publications

Affiliations: 
Biochemistry & Molecular Biology Drexel University College of Medicine, Philadelphia, PA, United States 
Area:
ligand gated ion channels
NOTE: We are testing a new system for identifying relevant work based on semantic analysis that identifies similarities between recently published papers and the current author's publications. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches.
50 most relevant papers in past 60 days:
Year Citation  Score
2020 Salazar H, Mischke S, Plested AJR. Measurements of the Timescale and Conformational Space of AMPA Receptor Desensitization. Biophysical Journal. PMID 32559412 DOI: 10.1016/j.bpj.2020.05.029   
2020 Chou TH, Tajima N, Romero-Hernandez A, Furukawa H. Structural Basis of Functional Transitions in Mammalian NMDA Receptors. Cell. PMID 32610085 DOI: 10.1016/j.cell.2020.05.052   
2020 Oliveira ASF, Ibarra AA, Bermudez I, Casalino L, Gaieb Z, Shoemark DK, Gallagher T, Sessions RB, Amaro RE, Mulholland AJ. Simulations support the interaction of the SARS-CoV-2 spike protein with nicotinic acetylcholine receptors and suggest subtype specificity. Biorxiv : the Preprint Server For Biology. PMID 32743575 DOI: 10.1101/2020.07.16.206680   
2020 Changeux JP. Golden Anniversary of the Nicotinic Receptor. Neuron. 107: 14-16. PMID 32645305 DOI: 10.1016/j.neuron.2020.05.026   
2020 Corrie LW, Stokes C, Wilkerson JL, Carroll FI, McMahon LR, Papke RL. Nicotinic Acetylcholine Receptor Accessory Subunits Determine the Activity Profile of Epibatidine Derivatives. Molecular Pharmacology. PMID 32690626 DOI: 10.1124/molpharm.120.000037   
2020 Che C, Zeng Y, Xu Y, Lu H, Xu Y, Zhang X, Xiao Y, Li JQ, Qin Z. APAn, a Class of ABA Receptor Agonism/antagonism Switching Probes. Journal of Agricultural and Food Chemistry. PMID 32687337 DOI: 10.1021/acs.jafc.0c02154   
2020 Rufener L, Kaur K, Sarr A, Aaen SM, Horsberg TE. Nicotinic acetylcholine receptors: Ex-vivo expression of functional, non-hybrid, heteropentameric receptors from a marine arthropod, Lepeophtheirus salmonis. Plos Pathogens. 16: e1008715. PMID 32716968 DOI: 10.1371/journal.ppat.1008715   
2020 Marcovich I, Moglie MJ, Carpaneto Freixas AE, Trigila AP, Franchini LF, Plazas PV, Lipovsek M, Elgoyhen AB. Distinct Evolutionary Trajectories of Neuronal and Hair Cell Nicotinic Acetylcholine Receptors. Molecular Biology and Evolution. 37: 1070-1089. PMID 31821508 DOI: 10.1093/molbev/msz290   
2020 Stephens BS, Ngo T, Kufareva I, Handel TM. Functional anatomy of the full-length CXCR4-CXCL12 complex systematically dissected by quantitative model-guided mutagenesis. Science Signaling. 13. PMID 32665413 DOI: 10.1126/scisignal.aay5024   
2020 Zaccor NW, Sumner CJ, Snyder SH. The nonselective cation channel TRPV4 inhibits angiotensin II receptors. The Journal of Biological Chemistry. PMID 32493776 DOI: 10.1074/jbc.RA120.014325   
2020 Friedman S, Tauber M, Ben-Chaim Y. Sodium ions allosterically modulate the M2 muscarinic receptor. Scientific Reports. 10: 11177. PMID 32636499 DOI: 10.1038/s41598-020-68133-9   
2020 Mattedi G, Acosta-Gutiérrez S, Clark T, Gervasio FL. A combined activation mechanism for the glucagon receptor. Proceedings of the National Academy of Sciences of the United States of America. PMID 32571939 DOI: 10.1073/pnas.1921851117   
2020 Yu Liao VW, Kusay AS, Balle T, Ahring PK. Heterologous expression of concatenated nicotine acetylcholine receptors: pros and cons of subunit concatenation and recommendations for construct designs. British Journal of Pharmacology. PMID 32627170 DOI: 10.1111/bph.15188   
2020 Brimson JM, Akula KK, Abbas H, Ferry DR, Kulkarni SK, Russell ST, Tisdale MJ, Tencomnao T, Safrany ST. Simple ammonium salts acting on sigma-1 receptors yield potential treatments for cancer and depression. Scientific Reports. 10: 9251. PMID 32514120 DOI: 10.1038/s41598-020-65849-6   
2020 Dalby NO, Falk-Petersen CB, Leurs U, Scholze P, Krall J, Frølund B, Wellendorph P. Silencing of spontaneous activity at α4β1/3δ GABA receptors in hippocampal granule cells reveals different ligand pharmacology. British Journal of Pharmacology. PMID 32484592 DOI: 10.1111/bph.15146   
2020 Lillo A, Martínez-Pinilla E, Reyes-Resina I, Navarro G, Franco R. Adenosine A and A Receptors Are Able to Interact with Each Other. A Further Piece in the Puzzle of Adenosine Receptor-Mediated Signaling. International Journal of Molecular Sciences. 21. PMID 32709103 DOI: 10.3390/ijms21145070   
2020 Sun HS, Yang QR, Bai YY, Hu NW, Liu DX, Qin CY. Gene testing for osteonecrosis of the femoral head in systemic lupus erythematosus using targeted next-generation sequencing: A pilot study. World Journal of Clinical Cases. 8: 2530-2541. PMID 32607330 DOI: 10.12998/wjcc.v8.i12.2530   
2020 Spillmann M, Thurner L, Romantini N, Zimmermann M, Meger B, Behe M, Waldhoer M, Schertler GFX, Berger P. New Insights into Arrestin Recruitment to GPCRs. International Journal of Molecular Sciences. 21. PMID 32668755 DOI: 10.3390/ijms21144949   
2020 Fischer JP, Els-Heindl S, Beck-Sickinger AG. Adrenomedullin - Current Perspective on a Peptide Hormone with Significant Therapeutic Potential. Peptides. 170347. PMID 32569606 DOI: 10.1016/j.peptides.2020.170347   
2020 Gillet C, Kurth S, Kuenzel T. Muscarinic modulation of M and h currents in gerbil spherical bushy cells. Plos One. 15: e0226954. PMID 31940388 DOI: 10.1371/journal.pone.0226954   
2020 Rumpret M, Drylewicz J, Ackermans LJE, Borghans JAM, Medzhitov R, Meyaard L. Functional categories of immune inhibitory receptors. Nature Reviews. Immunology. PMID 32612208 DOI: 10.1038/s41577-020-0352-z   
2020 Al Noman MA, Kyzer J, Chung SSW, Wolgemuth DJ, Georg GI. Retinoic acid receptor antagonists for male contraception: Current status. Biology of Reproduction. PMID 32671394 DOI: 10.1093/biolre/ioaa122   
2020 Gutjahr A, Papagno L, Vernejoul F, Lioux T, Jospin F, Chanut B, Perouzel E, Rochereau N, Appay V, Verrier B, Paul S. New chimeric TLR7/NOD2 agonist is a potent adjuvant to induce mucosal immune responses. Ebiomedicine. 58: 102922. PMID 32739871 DOI: 10.1016/j.ebiom.2020.102922   
2020 Gutjahr A, Papagno L, Vernejoul F, Lioux T, Jospin F, Chanut B, Perouzel E, Rochereau N, Appay V, Verrier B, Paul S. New chimeric TLR7/NOD2 agonist is a potent adjuvant to induce mucosal immune responses. Ebiomedicine. 58: 102922. PMID 32739871 DOI: 10.1016/j.ebiom.2020.102922   
2020 Clark LJ, Krieger J, White AD, Bondarenko V, Lei S, Fang F, Lee JY, Doruker P, Böttke T, Jean-Alphonse F, Tang P, Gardella TJ, Xiao K, Sutkeviciute I, Coin I, et al. Allosteric interactions in the parathyroid hormone GPCR-arrestin complex formation. Nature Chemical Biology. PMID 32632293 DOI: 10.1038/s41589-020-0567-0   
2020 Gelfuso EA, Reis SL, Aguiar DSR, Faggion SA, Gomes FMM, Galan DT, Peigneur S, Pereira AMS, Mortari MR, Cunha AOS, Tytgat J, Beleboni RO. New insights in the mode of action of (+)-erythravine and (+)-11α-hydroxy-erythravine alkaloids. European Journal of Pharmacology. 173390. PMID 32735983 DOI: 10.1016/j.ejphar.2020.173390   
2020 Motawe ZY, Abdelmaboud SS, Cuevas J, Breslin JW. PRE-084 as a tool to uncover potential therapeutic applications for selective sigma-1 receptor activation. The International Journal of Biochemistry & Cell Biology. 126: 105803. PMID 32668330 DOI: 10.1016/j.biocel.2020.105803   
2020 Ortega G, Mariottini D, Troina A, Dahlquist FW, Ricci F, Plaxco KW. Rational design to control the trade-off between receptor affinity and cooperativity. Proceedings of the National Academy of Sciences of the United States of America. PMID 32727893 DOI: 10.1073/pnas.2006254117   
2020 Gao C, Zeng J, Jia N, Stavenhagen K, Matsumoto Y, Zhang H, Li J, Hume AJ, Mühlberger E, van Die I, Kwan J, Tantisira K, Emili A, Cummings RD. SARS-CoV-2 Spike Protein Interacts with Multiple Innate Immune Receptors. Biorxiv : the Preprint Server For Biology. PMID 32766577 DOI: 10.1101/2020.07.29.227462   
2020 Yang X, Dilweg MA, Osemwengie D, Burggraaff L, van der Es D, Heitman LH, IJzerman AP. Design and Pharmacological Profile of a Novel Covalent Partial Agonist for the Adenosine A Receptor. Biochemical Pharmacology. 114144. PMID 32653590 DOI: 10.1016/j.bcp.2020.114144   
2020 Krintel C, Dorosz J, Larsen AH, Seneca Thorsen T, Venskutonytė R, Mirza O, Gajhede M, Boesen T, Kastrup JS. Binding of a negative allosteric modulator and competitive antagonist can occur simultaneously at the ionotropic glutamate receptor GluA2. The Febs Journal. PMID 32543078 DOI: 10.1111/febs.15455   
2020 Chin AC, Yovanno RA, Wied TJ, Gershman A, Lau AY. D-Serine Potently Drives Ligand-Binding Domain Closure in the Ionotropic Glutamate Receptor GluD2. Structure (London, England : 1993). PMID 32735769 DOI: 10.1016/j.str.2020.07.005   
2020 Nirthanan S. Snake three-finger α-neurotoxins and nicotinic acetylcholine receptors: molecules, mechanisms and medicine. Biochemical Pharmacology. 114168. PMID 32710970 DOI: 10.1016/j.bcp.2020.114168   
2020 Xu Q, Tae HS, Wang Z, Jiang T, Adams DJ, Yu R. Rational Design of α-Conotoxin RegIIA Analogues Specifically Inhibiting the Human α3β2 Nicotinic Acetylcholine Receptor through Computational Scanning. Acs Chemical Neuroscience. PMID 32649832 DOI: 10.1021/acschemneuro.0c00293   
2020 Falk-Petersen CB, Tsonkov TM, Nielsen MS, Harpsøe K, Bundgaard C, Frølund B, Kristiansen U, Gloriam DE, Wellendorph P. Discovery of a new class of orthosteric antagonists with nanomolar potency at extrasynaptic GABA receptors. Scientific Reports. 10: 10078. PMID 32572053 DOI: 10.1038/s41598-020-66821-0   
2020 Intagliata S, Sharma A, King TI, Mesangeau C, Seminerio M, Chin FT, Wilson LL, Matsumoto RR, McLaughlin JP, Avery BA, McCurdy CR. Discovery of a Highly Selective Sigma-2 Receptor Ligand, 1-(4-(6,7-Dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)butyl)-3-methyl-1H-benzo[d]imidazol-2(3H)-one (CM398), with Drug-Like Properties and Antinociceptive Effects In Vivo. The Aaps Journal. 22: 94. PMID 32691179 DOI: 10.1208/s12248-020-00472-x   
2020 Germann AL, Reichert DE, Burbridge AB, Pierce SR, Evers AS, Steinbach JH, Akk G. Analysis of modulation of the ρ1 GABAA receptor by combinations of inhibitory and potentiating neurosteroids reveals shared and distinct binding sites. Molecular Pharmacology. PMID 32675382 DOI: 10.1124/mol.120.119842   
2020 McGrath M, Hoyt H, Pence A, Jayakar SS, Zhou X, Forman SA, Cohen JB, Miller KW, Raines DE. Competitive Antagonism of Etomidate Action by Diazepam: In Vitro GABAA Receptor and In Vivo Zebrafish Studies. Anesthesiology. PMID 32541553 DOI: 10.1097/ALN.0000000000003403   
2020 Georges GJ, Dengl S, Bujotzek A, Hesse F, Fischer JAA, Gärtner A, Benz J, Lauer ME, Ringler P, Stahlberg H, Plath F, Brinkmann U, Imhof-Jung S. The Contorsbody, an antibody format for agonism: Design, structure, and function. Computational and Structural Biotechnology Journal. 18: 1210-1220. PMID 32542107 DOI: 10.1016/j.csbj.2020.05.007   
2020 Drimousis S, Markus I, Murphy TV, Perera DS, Phan-Thien KC, Zhang L, Liu L. Gender-related differences of tachykinin NK receptor expression and activity in human colonic smooth muscle. The Journal of Pharmacology and Experimental Therapeutics. PMID 32764152 DOI: 10.1124/jpet.120.265967   
2020 Richendrfer HA, Levy MM, Elsaid KA, Schmidt TA, Zhang L, Cabezas R, Jay GD. Recombinant Human Proteoglycan-4 Mediates Interleukin-6 Response in Both Human and Mouse Endothelial Cells Induced Into a Sepsis Phenotype. Critical Care Explorations. 2: e0126. PMID 32695993 DOI: 10.1097/CCE.0000000000000126   
2020 Li X, Shen L, Hua T, Liu ZJ. Structural and Functional Insights into Cannabinoid Receptors. Trends in Pharmacological Sciences. PMID 32739033 DOI: 10.1016/j.tips.2020.06.010   
2020 Kim HR, Xu J, Maeda S, Duc NM, Ahn D, Du Y, Chung KY. Structural mechanism underlying primary and secondary coupling between GPCRs and the Gi/o family. Nature Communications. 11: 3160. PMID 32572026 DOI: 10.1038/s41467-020-16975-2   
2020 Akk G, Germann AL, Sugasawa Y, Pierce SR, Evers AS, Steinbach JH. Enhancement of muscimol binding and gating by allosteric modulators of the GABA receptor: relating occupancy to state functions. Molecular Pharmacology. PMID 32723768 DOI: 10.1124/molpharm.120.000066   
2020 Roderer D, Bröcker F, Sitsel O, Kaplonek P, Leidreiter F, Seeberger PH, Raunser S. Glycan-dependent cell adhesion mechanism of Tc toxins. Nature Communications. 11: 2694. PMID 32483155 DOI: 10.1038/s41467-020-16536-7   
2020 Fujii N, McGarr GW, Ghassa R, Schmidt MD, McCormick JJ, Nishiyasu T, Kenny GP. Sex-differences in cholinergic, nicotinic, and β-adrenergic cutaneous vasodilation: Roles of nitric oxide synthase, cyclooxygenase, and K channels. Microvascular Research. 131: 104030. PMID 32531353 DOI: 10.1016/j.mvr.2020.104030   
2020 Magno AL, Leatherbarrow KM, Brown SJ, Wilson SG, Walsh JP, Ward BK. Functional Analysis of Calcium-Sensing Receptor Variants Identified in Families Provisionally Diagnosed with Familial Hypocalciuric Hypercalcaemia. Calcified Tissue International. PMID 32638038 DOI: 10.1007/s00223-020-00715-1   
2020 Tian J, He Y, Deuther-Conrad W, Fu H, Xie F, Zhang Y, Wang T, Zhang X, Zhang J, Brust P, Huang Y, Jia H. Synthesis and evaluation of new 1-oxa-8-azaspiro[4.5]decane derivatives as candidate radioligands for sigma-1 receptors. Bioorganic & Medicinal Chemistry. 28: 115560. PMID 32616183 DOI: 10.1016/j.bmc.2020.115560   
2020 He YC, Yan YM, Tong HB, Ren ZX, Wang JH, Zhang YB, Chao JB, Wang ML. Benzenebistriazole-strapped calix[4]pyrrole: a neutral anion receptor with CH and NH donor groups that exhibits high sulfate binding affinity and selectivity in aqueous solutions. Chemical Communications (Cambridge, England). PMID 32672309 DOI: 10.1039/d0cc03655b   
2020 Wasilko DJ, Johnson ZL, Ammirati M, Che Y, Griffor MC, Han S, Wu H. Structural basis for chemokine receptor CCR6 activation by the endogenous protein ligand CCL20. Nature Communications. 11: 3031. PMID 32541785 DOI: 10.1038/s41467-020-16820-6