Audrey Claing, Ph.D - Publications

Affiliations: 
Pharmacologie Université de Montréal, Montréal, Canada 
Area:
GPCRs
Website:
http://www.pharmacologie.umontreal.ca/professeurs_chercheurs/claing/index.html

73 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Giubilaro J, Schuetz DA, Stepniewski TM, Namkung Y, Khoury E, Lara-Márquez M, Campbell S, Beautrait A, Armando S, Radresa O, Duchaine J, Lamarche-Vane N, Claing A, Selent J, Bouvier M, et al. Discovery of a dual Ras and ARF6 inhibitor from a GPCR endocytosis screen. Nature Communications. 12: 4688. PMID 34344896 DOI: 10.1038/s41467-021-24968-y  1
2021 Zhao X, Campbell S, El-Khoury PZ, Jia Y, Wallace GQ, Claing A, Bazuin CG, Masson JF. Surface-Enhanced Raman Scattering Optophysiology Nanofibers for the Detection of Heavy Metals in Single Breast Cancer Cells. Acs Sensors. 6: 1649-1662. PMID 33847111 DOI: 10.1021/acssensors.1c00332  1
2020 Zhao X, Campbell S, Wallace G, Claing A, Bazuin CG, Masson JF. Branched Au Nanoparticles on Nanofibers for Surface-Enhanced Raman Scattering Sensing of Intracellular pH and Extracellular pH Gradients. Acs Sensors. PMID 32515184 DOI: 10.1021/Acssensors.0C00784  1
2019 Charles R, Bourmoum M, Campbell S, Claing A. Methods to Investigate the β-Arrestin-Mediated Control of ARF6 Activation to Regulate Trafficking and Actin Cytoskeleton Remodeling. Methods in Molecular Biology (Clifton, N.J.). 1957: 159-168. PMID 30919353 DOI: 10.1007/978-1-4939-9158-7_10  1
2019 Rajchgot T, Thomas SC, Wang JC, Ahmadi M, Balood M, Crosson T, Dias JP, Couture R, Claing A, Talbot S. Neurons and Microglia; A Sickly-Sweet Duo in Diabetic Pain Neuropathy. Frontiers in Neuroscience. 13: 25. PMID 30766472 DOI: 10.3389/Fnins.2019.00025  0.01
2018 Bourmoum M, Charles R, Claing A. ARF6 protects sister chromatid cohesion to ensure the formation of stable kinetochore-microtubule attachments. Journal of Cell Science. PMID 29724911 DOI: 10.1242/Jcs.216598  1
2018 Charles R, Bourmoum M, Claing A. ARF GTPases control phenotypic switching of vascular smooth muscle cells through the regulation of actin function and actin dependent gene expression. Cellular Signalling. PMID 29499306 DOI: 10.1016/J.Cellsig.2018.02.012  1
2017 Sadekova N, Iulita MF, Vallerand D, Muhire G, Bourmoum M, Claing A, Girouard H. Arterial stiffness induced by carotid calcification leads to cerebral gliosis mediated by oxidative stress. Journal of Hypertension. PMID 28938336 DOI: 10.1097/Hjh.0000000000001557  1
2017 Aubé A, Campbell S, Schmitzer AR, Claing A, Masson JF. Correction: Ultra-low fouling alkylimidazolium modified surfaces for the detection of HER2 in breast cancer cell lysates. The Analyst. PMID 28748975 DOI: 10.1039/C7An90058A  1
2017 Aubé A, Campbell S, Schmitzer AR, Claing A, Masson JF. Ultra-low fouling methylimidazolium modified surfaces for the detection of HER2 in breast cancer cell lysates. The Analyst. PMID 28560368 DOI: 10.1039/C7An00056A  1
2017 Bourmoum M, Claing A. The GTPase ARF6 Regulates Mitotic Exit and Cell Cycle Progression Journal of Pharmacological and Toxicological Methods. 88: 169. DOI: 10.1016/J.Vascn.2017.09.008  1
2016 Chingle R, Ratni S, Claing A, Lubell WD. Application of constrained aza-valine analogs for Smac mimicry. Biopolymers. PMID 27087660 DOI: 10.1002/Bip.22851  1
2016 Schlienger S, Campbell S, Pasquin S, Gaboury L, Claing A. ADP-ribosylation factor 1 expression regulates epithelial-mesenchymal transition and predicts poor clinical outcome in triple-negative breast cancer. Oncotarget. PMID 26908458 DOI: 10.18632/Oncotarget.7515  1
2016 Bourmoum M, Charles R, Claing A. The GTPase ARF6 Controls ROS Production to Mediate Angiotensin II-Induced Vascular Smooth Muscle Cell Proliferation. Plos One. 11: e0148097. PMID 26824355 DOI: 10.1371/Journal.Pone.0148097  1
2015 Charles R, Namkung Y, Cotton M, Laporte SA, Claing A. βarrestin-Mediated Angiotensin II Signaling Controls the Activation of ARF6 and Endocytosis in Migration of Vascular Smooth Muscle Cells. The Journal of Biological Chemistry. PMID 26703465 DOI: 10.1074/Jbc.M115.684357  1
2015 Haines E, Schlienger S, Claing A. The small GTPase ADP-Ribosylation Factor 1 mediates the sensitivity of triple negative breast cancer cells to EGFR tyrosine kinase inhibitors. Cancer Biology & Therapy. 0. PMID 26176330 DOI: 10.1080/15384047.2015.1071737  1
2015 Boukanoun MK, Hou X, Nikolajev L, Ratni S, Olson D, Claing A, Laporte SA, Chemtob S, Lubell WD. Investigation of the active turn geometry for the labour delaying activity of indolizidinone and azapeptide modulators of the prostaglandin F2α receptor. Organic & Biomolecular Chemistry. PMID 26090777 DOI: 10.1039/C5Ob00962F  1
2015 Schlienger S, Ramirez RA, Claing A. ARF1 regulates adhesion of MDA-MB-231 invasive breast cancer cells through formation of focal adhesions. Cellular Signalling. 27: 403-15. PMID 25530216 DOI: 10.1016/J.Cellsig.2014.11.032  1
2014 Bourguet CB, Boulay PL, Claing A, Lubell WD. Design and synthesis of novel azapeptide activators of apoptosis mediated by caspase-9 in cancer cells. Bioorganic & Medicinal Chemistry Letters. 24: 3361-5. PMID 24986663 DOI: 10.1016/J.Bmcl.2014.05.095  1
2014 Haines E, Saucier C, Claing A. The adaptor proteins p66Shc and Grb2 regulate the activation of the GTPases ARF1 and ARF6 in invasive breast cancer cells. The Journal of Biological Chemistry. 289: 5687-703. PMID 24407288 DOI: 10.1074/Jbc.M113.516047  1
2014 Schlienger S, Campbell S, Claing A. ARF1 regulates the Rho/MLC pathway to control EGF-dependent breast cancer cell invasion. Molecular Biology of the Cell. 25: 17-29. PMID 24196838 DOI: 10.1091/Mbc.E13-06-0335  1
2014 Bourguet CB, Claing A, Laporte SA, Hébert TE, Chemtob S, Lubell WD. Synthesis of azabicycloalkanone amino acid and azapeptide mimics and their application as modulators of the prostaglandin F2α receptor for delaying preterm birth Canadian Journal of Chemistry. 92: 1031-1040. DOI: 10.1139/cjc-2014-0289  1
2014 Vidal M, Elie CR, Campbell S, Claing A, Schmitzer AR. Biologically active binaphthol-scaffolded imidazolium salts Medchemcomm. 5: 436-440. DOI: 10.1039/C3Md00293D  1
2013 Claing A. β-Arrestins: modulators of small GTPase activation and function. Progress in Molecular Biology and Translational Science. 118: 149-74. PMID 23764053 DOI: 10.1016/B978-0-12-394440-5.00006-1  1
2013 Lewis-Saravalli S, Campbell S, Claing A. ARF1 controls Rac1 signaling to regulate migration of MDA-MB-231 invasive breast cancer cells. Cellular Signalling. 25: 1813-9. PMID 23707487 DOI: 10.1016/J.Cellsig.2013.05.011  1
2012 Zimmerman B, Beautrait A, Aguila B, Charles R, Escher E, Claing A, Bouvier M, Laporte SA. Differential β-arrestin-dependent conformational signaling and cellular responses revealed by angiotensin analogs. Science Signaling. 5: ra33. PMID 22534132 DOI: 10.1126/Scisignal.2002522  1
2011 Bourguet CB, Goupil E, Tassy D, Hou X, Thouin E, Polyak F, Hébert TE, Claing A, Laporte SA, Chemtob S, Lubell WD. Targeting the prostaglandin F2α receptor for preventing preterm labor with azapeptide tocolytics. Journal of Medicinal Chemistry. 54: 6085-97. PMID 21774512 DOI: 10.1021/Jm200608K  1
2011 Boulay PL, Schlienger S, Lewis-Saravalli S, Vitale N, Ferbeyre G, Claing A. ARF1 controls proliferation of breast cancer cells by regulating the retinoblastoma protein. Oncogene. 30: 3846-61. PMID 21478909 DOI: 10.1038/Onc.2011.100  1
2010 Goupil E, Tassy D, Bourguet C, Quiniou C, Wisehart V, Pétrin D, Le Gouill C, Devost D, Zingg HH, Bouvier M, Saragovi HU, Chemtob S, Lubell WD, Claing A, Hébert TE, et al. A novel biased allosteric compound inhibitor of parturition selectively impedes the prostaglandin F2alpha-mediated Rho/ROCK signaling pathway. The Journal of Biological Chemistry. 285: 25624-36. PMID 20551320 DOI: 10.1074/Jbc.M110.115196  1
2010 Daher Z, Boulay PL, Desjardins F, Gratton JP, Claing A. Vascular endothelial growth factor receptor-2 activates ADP-ribosylation factor 1 to promote endothelial nitric-oxide synthase activation and nitric oxide release from endothelial cells. The Journal of Biological Chemistry. 285: 24591-9. PMID 20529868 DOI: 10.1074/Jbc.M110.115311  1
2009 Boulay PL, Claing A. [ARF proteins: molecular switches controlling tumour proliferation and metastasis]. Mã©Decine Sciences : M/S. 25: 783-5. PMID 19849973 DOI: 10.1051/Medsci/20092510783  1
2009 Cotton M, Claing A. G protein-coupled receptors stimulation and the control of cell migration. Cellular Signalling. 21: 1045-53. PMID 19249352 DOI: 10.1016/J.Cellsig.2009.02.008  1
2008 Boulay PL, Cotton M, Melançon P, Claing A. ADP-ribosylation factor 1 controls the activation of the phosphatidylinositol 3-kinase pathway to regulate epidermal growth factor-dependent growth and migration of breast cancer cells. The Journal of Biological Chemistry. 283: 36425-34. PMID 18990689 DOI: 10.1074/Jbc.M803603200  1
2008 Daher Z, Noël J, Claing A. Endothelin-1 promotes migration of endothelial cells through the activation of ARF6 and the regulation of FAK activity. Cellular Signalling. 20: 2256-65. PMID 18814847 DOI: 10.1016/J.Cellsig.2008.08.021  1
2007 Poupart ME, Fessart D, Cotton M, Laporte SA, Claing A. ARF6 regulates angiotensin II type 1 receptor endocytosis by controlling the recruitment of AP-2 and clathrin. Cellular Signalling. 19: 2370-8. PMID 17719203 DOI: 10.1016/J.Cellsig.2007.07.015  1
2007 Cotton M, Boulay PL, Houndolo T, Vitale N, Pitcher JA, Claing A. Endogenous ARF6 interacts with Rac1 upon angiotensin II stimulation to regulate membrane ruffling and cell migration. Molecular Biology of the Cell. 18: 501-11. PMID 17122362 DOI: 10.1091/Mbc.E06-06-0567  1
2006 Giguère P, Rochdi MD, Laroche G, Dupré E, Whorton MR, Sunahara RK, Claing A, Dupuis G, Parent JL. ARF6 activation by Galpha q signaling: Galpha q forms molecular complexes with ARNO and ARF6. Cellular Signalling. 18: 1988-94. PMID 16650966 DOI: 10.1016/J.Cellsig.2006.03.003  1
2005 Claing A, Laporte SA. Novel roles for arrestins in G protein-coupled receptor biology and drug discovery. Current Opinion in Drug Discovery & Development. 8: 585-9. PMID 16159020  1
2005 Houndolo T, Boulay PL, Claing A. G protein-coupled receptor endocytosis in ADP-ribosylation factor 6-depleted cells. The Journal of Biological Chemistry. 280: 5598-604. PMID 15590645 DOI: 10.1074/Jbc.M411456200  1
2004 Claing A. Regulation of G protein-coupled receptor endocytosis by ARF6 GTP-binding proteins. Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire. 82: 610-7. PMID 15674428 DOI: 10.1139/O04-113  1
2004 Premont RT, Perry SJ, Schmalzigaug R, Roseman JT, Xing Y, Claing A. The GIT/PIX complex: an oligomeric assembly of GIT family ARF GTPase-activating proteins and PIX family Rac1/Cdc42 guanine nucleotide exchange factors. Cellular Signalling. 16: 1001-11. PMID 15212761 DOI: 10.1016/J.Cellsig.2004.02.002  1
2002 Freeman JL, Gonzalo P, Pitcher JA, Claing A, Lavergne JP, Reboud JP, Lefkowitz RJ. Beta 2-adrenergic receptor stimulated, G protein-coupled receptor kinase 2 mediated, phosphorylation of ribosomal protein P2. Biochemistry. 41: 12850-7. PMID 12379128 DOI: 10.1021/Bi020145D  1
2002 Claing A, Laporte SA, Caron MG, Lefkowitz RJ. Endocytosis of G protein-coupled receptors: roles of G protein-coupled receptor kinases and beta-arrestin proteins. Progress in Neurobiology. 66: 61-79. PMID 11900882 DOI: 10.1016/S0301-0082(01)00023-5  1
2002 Claing A, Shbaklo H, Plante M, Bkaily G, D'Orléans-Juste P. Comparison of the contractile and calcium-increasing properties of platelet-activating factor and endothelin-1 in the rat mesenteric artery and vein. British Journal of Pharmacology. 135: 433-43. PMID 11815379 DOI: 10.1038/Sj.Bjp.0704441  1
2001 Cong M, Perry SJ, Hu LA, Hanson PI, Claing A, Lefkowitz RJ. Binding of the beta2 adrenergic receptor to N-ethylmaleimide-sensitive factor regulates receptor recycling. The Journal of Biological Chemistry. 276: 45145-52. PMID 11577089 DOI: 10.1074/Jbc.M106087200  1
2001 Claing A, Chen W, Miller WE, Vitale N, Moss J, Premont RT, Lefkowitz RJ. beta-Arrestin-mediated ADP-ribosylation factor 6 activation and beta 2-adrenergic receptor endocytosis. The Journal of Biological Chemistry. 276: 42509-13. PMID 11533043 DOI: 10.1074/Jbc.M108399200  1
2000 Premont RT, Claing A, Vitale N, Perry SJ, Lefkowitz RJ. The GIT family of ADP-ribosylation factor GTPase-activating proteins. Functional diversity of GIT2 through alternative splicing. The Journal of Biological Chemistry. 275: 22373-80. PMID 10896954 DOI: 10.1074/Jbc.275.29.22373  1
2000 Claing A, Perry SJ, Achiriloaie M, Walker JK, Albanesi JP, Lefkowitz RJ, Premont RT. Multiple endocytic pathways of G protein-coupled receptors delineated by GIT1 sensitivity. Proceedings of the National Academy of Sciences of the United States of America. 97: 1119-24. PMID 10655494 DOI: 10.1073/Pnas.97.3.1119  1
1998 Premont RT, Claing A, Vitale N, Freeman JL, Pitcher JA, Patton WA, Moss J, Vaughan M, Lefkowitz RJ. beta2-Adrenergic receptor regulation by GIT1, a G protein-coupled receptor kinase-associated ADP ribosylation factor GTPase-activating protein. Proceedings of the National Academy of Sciences of the United States of America. 95: 14082-7. PMID 9826657 DOI: 10.1073/Pnas.95.24.14082  1
1998 Hall RA, Premont RT, Chow CW, Blitzer JT, Pitcher JA, Claing A, Stoffel RH, Barak LS, Shenolikar S, Weinman EJ, Grinstein S, Lefkowitz RJ. The beta2-adrenergic receptor interacts with the Na+/H+-exchanger regulatory factor to control Na+/H+ exchange. Nature. 392: 626-30. PMID 9560162 DOI: 10.1038/33458  1
1998 Krueger KM, Claing A, Lefkowitz RJ. Mutagenesis of acidic residues in the β2-adrenergic receptor abolishes the requirement of low pH for receptor dephosphorylation Faseb Journal. 12: A742.  1
1996 D'Orléans-Juste P, Claing A, Regoli D, Sirois P, Plante GE. Endothelial and smooth muscle pharmacology of pre- and post-capillary microcirculation: correlation with plasma extravasation. Prostaglandins, Leukotrienes, and Essential Fatty Acids. 54: 31-7. PMID 8992491 DOI: 10.1016/S0952-3278(96)90078-2  1
1996 D'Orléans-Juste P, Berthiaume N, Plante GE, Bkaily G, Claing A. Comparison of the pre- and post-capillary vascular reactivity in the rat and guinea pig perfused mesenteric bed. Canadian Journal of Physiology and Pharmacology. 74: 811-7. PMID 8946067 DOI: 10.1139/cjpp-74-7-811  1
1996 D'orleans-Juste P, Gratton J-, Leduc R, Bkaily G, Claing A. L'endothéline : pharmacologie cardiovasculaire et considérations physio-pathologiques M S-Medecine Sciences. 12: 563-574. DOI: 10.4267/10608/785  1
1996 D'Orléans-Juste P, Gratton JP, Leduc R, Bkaily G, Claing A. Endothelin cardiovascular pharmacology and pathophysiology | L'ENDOTHELINE: PHARMACOLOGIE CARDIOVASCULAIRE ET CONSIDERATIONS PHYSIOPATHOLOGIQUES Medecine/Sciences. 12: 563-574.  1
1995 Berthiaume N, Claing A, Lippton H, Cadieux A, D'Orléans-Juste P. Rat adrenomedullin induces a selective arterial vasodilation via CGRP1 receptors in the double-perfused mesenteric bed of the rat. Canadian Journal of Physiology and Pharmacology. 73: 1080-3. PMID 8846405 DOI: 10.1139/Y95-154  1
1995 Claing A, Neugebauer W, Yano M, Rae GA, D'Orléans-Juste P. [Phe22]-big endothelin-1[19-37]: a new and potent inhibitor of the endothelin-converting enzyme. Journal of Cardiovascular Pharmacology. 26: S72-4. PMID 8587472 DOI: 10.1097/00005344-199506263-00023  1
1995 Berthiaume N, Claing A, Yano M, D'Orléans-Juste P. Characterization of receptors for endothelins in the guinea pig mesenteric vasculature. Journal of Cardiovascular Pharmacology. 26: S317-9. PMID 8587400 DOI: 10.1097/00005344-199506263-00095  1
1995 Gratton JP, Rae GA, Claing A, Télémaque S, D'Orléans-Juste P. Different pressor and bronchoconstrictor properties of human big-endothelin-1, 2 (1-38) and 3 in ketamine/xylazine-anaesthetized guinea-pigs. British Journal of Pharmacology. 114: 720-6. PMID 7735698 DOI: 10.1111/J.1476-5381.1995.Tb17198.X  1
1995 Denault JB, Claing A, D'Orléans-Juste P, Sawamura T, Kido T, Masaki T, Leduc R. Processing of proendothelin-1 by human furin convertase. Febs Letters. 362: 276-80. PMID 7729512 DOI: 10.1016/0014-5793(95)00249-9  1
1995 Morris JL, Gibbins IL, Kadowitz PJ, Herzog H, Kreulen DL, Toda N, Claing A. Roles of peptides and other substances in cotransmission from vascular autonomic and sensory neurons. Canadian Journal of Physiology and Pharmacology. 73: 521-32. PMID 7585317  1
1995 Berthiaume N, Claing A, Regoli D, Warner TD, D'Orléans-Juste P. Characterization of receptors for kinins and neurokinins in the arterial and venous mesenteric vasculatures of the guinea-pig. British Journal of Pharmacology. 115: 1319-25. PMID 7582563 DOI: 10.1111/J.1476-5381.1995.Tb15043.X  1
1994 Claing A, Bkaily G, Berthiaume N, Sirois P, Rola-Pleszczynski M, D'Orléans-Juste P. Role of R-type calcium channels in the response of the perfused arterial and venous mesenteric vasculature of the rat to platelet-activating factor. British Journal of Pharmacology. 112: 1202-8. PMID 7952882 DOI: 10.1111/J.1476-5381.1994.Tb13211.X  1
1994 D'Orléans-Juste P, Claing A, Télémaque S, Maurice MC, Yano M, Gratton JP. Block of endothelin-1-induced release of thromboxane A2 from the guinea pig lung and nitric oxide from the rabbit kidney by a selective ETB receptor antagonist, BQ-788. British Journal of Pharmacology. 113: 1257-62. PMID 7889281 DOI: 10.1111/J.1476-5381.1994.Tb17133.X  1
1993 Télémaque S, Gratton JP, Claing A, D'Orléans-Juste P. Endothelin-1 induces vasoconstriction and prostacyclin release via the activation of endothelin ETA receptors in the perfused rabbit kidney. European Journal of Pharmacology. 237: 275-81. PMID 8365455 DOI: 10.1016/0014-2999(93)90279-Q  1
1993 D'Orléans-Juste P, Claing A, Warner TD, Yano M, Télémaque S. Characterization of receptors for endothelins in the perfused arterial and venous mesenteric vasculatures of the rat. British Journal of Pharmacology. 110: 687-92. PMID 8242241 DOI: 10.1111/J.1476-5381.1993.Tb13866.X  1
1993 Rouissi N, Claing A, Nicolau M, Jukic D, D'Orléans-Juste P, Regoli D. Substance P (NK-1 receptor) antagonists: in vivo and in vitro activities in rats and guinea pigs. Life Sciences. 52: 1141-7. PMID 7680744 DOI: 10.1016/0024-3205(93)90436-7  1
1993 Télémaque S, Gratton JP, Claing A, D'Orléans-Juste P. Pharmacologic evidence for the specificity of the phosphoramidon-sensitive endothelin-converting enzyme for big endothelin-1. Journal of Cardiovascular Pharmacology. 22: S85-9. PMID 7510007 DOI: 10.1097/00005344-199322008-00024  1
1992 Télémaque S, Lemaire D, Claing A, D'Orléans-Juste P. Phosphoramidon-sensitive effects of big endothelins in the perfused rabbit kidney. Hypertension. 20: 518-23. PMID 1398887 DOI: 10.1161/01.Hyp.20.4.518  1
1992 Claing A, Télémaque S, Cadieux A, Fournier A, Regoli D, D'Orléans-Juste P. Nonadrenergic and noncholinergic arterial dilatation and venoconstriction are mediated by calcitonin gene-related peptide1 and neurokinin-1 receptors, respectively, in the mesenteric vasculature of the rat after perivascular nerve stimulation. The Journal of Pharmacology and Experimental Therapeutics. 263: 1226-32. PMID 1335059  1
1992 D'Orléans-Juste P, Télémaque S, Claing A, Ihara M, Yano M. Human big-endothelin-1 and endothelin-1 release prostacyclin via the activation of ET1 receptors in the rat perfused lung. British Journal of Pharmacology. 105: 773-5. PMID 1324048 DOI: 10.1111/J.1476-5381.1992.Tb09055.X  1
1991 D'Orléans-Juste P, Télémaque S, Claing A. Different pharmacological profiles of big-endothelin-3 and big-endothelin-1 in vivo and in vitro. British Journal of Pharmacology. 104: 440-4. PMID 1797310 DOI: 10.1111/J.1476-5381.1991.Tb12448.X  1
1991 D'Orléans-Juste P, Claing A, Télémaque S, Warner TD, Regoli D. Neurokinins produce selective venoconstriction via NK-3 receptors in the rat mesenteric vascular bed. European Journal of Pharmacology. 204: 329-34. PMID 1723050 DOI: 10.1016/0014-2999(91)90860-S  1
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