Year |
Citation |
Score |
2013 |
Corbett BF, Leiser SC, Ling HP, Nagy R, Breysse N, Zhang X, Hazra A, Brown JT, Randall AD, Wood A, Pangalos MN, Reinhart PH, Chin J. Sodium channel cleavage is associated with aberrant neuronal activity and cognitive deficits in a mouse model of Alzheimer's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 7020-6. PMID 23595759 DOI: 10.1523/JNEUROSCI.2325-12.2013 |
1 |
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2011 |
Reinhart PH, Kelly JW. Treating the periphery to ameliorate neurodegenerative diseases. Cell. 145: 813-4. PMID 21663784 DOI: 10.1016/j.cell.2011.05.031 |
1 |
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2011 |
Reinhart PH, Kaltenbach LS, Essrich C, Dunn DE, Eudailey JA, DeMarco CT, Turmel GJ, Whaley JC, Wood A, Cho S, Lo DC. Identification of anti-inflammatory targets for Huntington's disease using a brain slice-based screening assay. Neurobiology of Disease. 43: 248-56. PMID 21458569 DOI: 10.1016/j.nbd.2011.03.017 |
1 |
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2010 |
Pungaliya PP, Bai Y, Lipinski K, Anand VS, Sen S, Brown EL, Bates B, Reinhart PH, West AB, Hirst WD, Braithwaite SP. Identification and characterization of a leucine-rich repeat kinase 2 (LRRK2) consensus phosphorylation motif. Plos One. 5: e13672. PMID 21060682 DOI: 10.1371/journal.pone.0013672 |
1 |
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2010 |
Hurko O, Boudonck K, Gonzales C, Hughes ZA, Jacobsen JS, Reinhart PH, Crowther D. Ablation of the locus coeruleus increases oxidative stress in tg-2576 transgenic but not wild-type mice. International Journal of Alzheimer's Disease. 2010: 864625. PMID 20981353 DOI: 10.4061/2010/864625 |
1 |
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2010 |
Braithwaite SP, Schmid RS, He DN, Sung ML, Cho S, Resnick L, Monaghan MM, Hirst WD, Essrich C, Reinhart PH, Lo DC. Inhibition of c-Jun kinase provides neuroprotection in a model of Alzheimer's disease. Neurobiology of Disease. 39: 311-7. PMID 20451607 DOI: 10.1016/j.nbd.2010.04.015 |
1 |
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2010 |
Zhou P, Li Y, Fan Y, Wang Z, Chopra R, Olland A, Hu Y, Magolda RL, Pangalos M, Reinhart PH, Turner MJ, Bard J, Malamas MS, Robichaud AJ. Pyridinyl aminohydantoins as small molecule BACE1 inhibitors. Bioorganic & Medicinal Chemistry Letters. 20: 2326-9. PMID 20202842 DOI: 10.1016/j.bmcl.2010.01.136 |
1 |
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2010 |
Monaghan MM, Leddy L, Sung ML, Albinson K, Kubek K, Pangalos MN, Reinhart PH, Zaleska MM, Comery TA. Social odor recognition: a novel behavioral model for cognitive dysfunction in Parkinson's disease. Neuro-Degenerative Diseases. 7: 153-9. PMID 20197696 DOI: 10.1159/000289227 |
1 |
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2009 |
Martone RL, Zhou H, Atchison K, Comery T, Xu JZ, Huang X, Gong X, Jin M, Kreft A, Harrison B, Mayer SC, Aschmies S, Gonzales C, Zaleska MM, Riddell DR, ... ... Reinhart PH, et al. Begacestat (GSI-953): a novel, selective thiophene sulfonamide inhibitor of amyloid precursor protein gamma-secretase for the treatment of Alzheimer's disease. The Journal of Pharmacology and Experimental Therapeutics. 331: 598-608. PMID 19671883 DOI: 10.1124/jpet.109.152975 |
1 |
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2009 |
Atkinson PJ, Dellovade T, Albers D, Von Schack D, Saraf K, Needle E, Reinhart PH, Hirst WD. Sonic Hedgehog signaling in astrocytes is dependent on p38 mitogen-activated protein kinase and G-protein receptor kinase 2. Journal of Neurochemistry. 108: 1539-49. PMID 19183261 DOI: 10.1111/j.1471-4159.2009.05900.x |
1 |
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2009 |
Anand VS, Reichling LJ, Lipinski K, Stochaj W, Duan W, Kelleher K, Pungaliya P, Brown EL, Reinhart PH, Somberg R, Hirst WD, Riddle SM, Braithwaite SP. Investigation of leucine-rich repeat kinase 2 : enzymological properties and novel assays. The Febs Journal. 276: 466-78. PMID 19076219 DOI: 10.1111/j.1742-4658.2008.06789.x |
1 |
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2008 |
Riddell DR, Zhou H, Atchison K, Warwick HK, Atkinson PJ, Jefferson J, Xu L, Aschmies S, Kirksey Y, Hu Y, Wagner E, Parratt A, Xu J, Li Z, Zaleska MM, ... ... Reinhart PH, et al. Impact of apolipoprotein E (ApoE) polymorphism on brain ApoE levels. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 11445-53. PMID 18987181 DOI: 10.1523/JNEUROSCI.1972-08.2008 |
1 |
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2008 |
Jacobsen JS, Comery TA, Martone RL, Elokdah H, Crandall DL, Oganesian A, Aschmies S, Kirksey Y, Gonzales C, Xu J, Zhou H, Atchison K, Wagner E, Zaleska MM, Das I, ... ... Reinhart PH, et al. Enhanced clearance of Abeta in brain by sustaining the plasmin proteolysis cascade. Proceedings of the National Academy of Sciences of the United States of America. 105: 8754-9. PMID 18559859 DOI: 10.1073/pnas.0710823105 |
1 |
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2008 |
Liu F, Day M, Muñiz LC, Bitran D, Arias R, Revilla-Sanchez R, Grauer S, Zhang G, Kelley C, Pulito V, Sung A, Mervis RF, Navarra R, Hirst WD, Reinhart PH, et al. Activation of estrogen receptor-beta regulates hippocampal synaptic plasticity and improves memory. Nature Neuroscience. 11: 334-43. PMID 18297067 DOI: 10.1038/nn2057 |
1 |
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2008 |
Ruan B, Pong K, Jow F, Bowlby M, Crozier RA, Liu D, Liang S, Chen Y, Mercado ML, Feng X, Bennett F, von Schack D, McDonald L, Zaleska MM, Wood A, ... Reinhart PH, et al. Binding of rapamycin analogs to calcium channels and FKBP52 contributes to their neuroprotective activities. Proceedings of the National Academy of Sciences of the United States of America. 105: 33-8. PMID 18162540 DOI: 10.1073/pnas.0710424105 |
1 |
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2007 |
Riddell DR, Zhou H, Comery TA, Kouranova E, Lo CF, Warwick HK, Ring RH, Kirksey Y, Aschmies S, Xu J, Kubek K, Hirst WD, Gonzales C, Chen Y, Murphy E, ... ... Reinhart PH, et al. The LXR agonist TO901317 selectively lowers hippocampal Abeta42 and improves memory in the Tg2576 mouse model of Alzheimer's disease. Molecular and Cellular Neurosciences. 34: 621-8. PMID 17336088 DOI: 10.1016/j.mcn.2007.01.011 |
1 |
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2006 |
Jacobsen JS, Wu CC, Redwine JM, Comery TA, Arias R, Bowlby M, Martone R, Morrison JH, Pangalos MN, Reinhart PH, Bloom FE. Early-onset behavioral and synaptic deficits in a mouse model of Alzheimer's disease. Proceedings of the National Academy of Sciences of the United States of America. 103: 5161-6. PMID 16549764 DOI: 10.1073/pnas.0600948103 |
1 |
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2005 |
Pangalos MN, Jacobsen SJ, Reinhart PH. Disease modifying strategies for the treatment of Alzheimer's disease targeted at modulating levels of the beta-amyloid peptide. Biochemical Society Transactions. 33: 553-8. PMID 16042543 DOI: 10.1042/BST0330553 |
1 |
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2005 |
Lu G, Henderson D, Liu L, Reinhart PH, Simon SA. TRPV1b, a functional human vanilloid receptor splice variant. Molecular Pharmacology. 67: 1119-27. PMID 15644492 DOI: 10.1124/mol.104.009852 |
1 |
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2004 |
Khoshnan A, Ko J, Watkin EE, Paige LA, Reinhart PH, Patterson PH. Activation of the IkappaB kinase complex and nuclear factor-kappaB contributes to mutant huntingtin neurotoxicity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 7999-8008. PMID 15371500 DOI: 10.1523/JNEUROSCI.2675-04.2004 |
1 |
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2004 |
Neylon CB, D'Souza T, Reinhart PH. Protein kinase A inhibits intermediate conductance Ca2+-activated K+ channels expressed in Xenopus oocytes. PflüGers Archiv : European Journal of Physiology. 448: 613-20. PMID 15243742 DOI: 10.1007/s00424-004-1302-5 |
1 |
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2003 |
Edgerton JR, Reinhart PH. Distinct contributions of small and large conductance Ca2+-activated K+ channels to rat Purkinje neuron function. The Journal of Physiology. 548: 53-69. PMID 12576503 DOI: 10.1113/jphysiol.2002.027854 |
1 |
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2002 |
Liu X, Chang Y, Reinhart PH, Sontheimer H, Chang Y. Cloning and characterization of glioma BK, a novel BK channel isoform highly expressed in human glioma cells. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 1840-9. PMID 11880513 |
1 |
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2001 |
Quirk JC, Reinhart PH. Identification of a novel tetramerization domain in large conductance K(ca) channels. Neuron. 32: 13-23. PMID 11604135 DOI: 10.1016/S0896-6273(01)00444-5 |
1 |
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2000 |
Welch JM, Simon SA, Reinhart PH. The activation mechanism of rat vanilloid receptor 1 by capsaicin involves the pore domain and differs from the activation by either acid or heat Proceedings of the National Academy of Sciences of the United States of America. 97: 13889-13894. PMID 11095706 DOI: 10.1073/pnas.230146497 |
1 |
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2000 |
Liu L, Welch JM, Erickson RP, Reinhart PH, Simon SA. Different responses to repeated applications of zingerone in behavioral studies, recordings from intact and cultured TG neurons, and from VR1 receptors. Physiology & Behavior. 69: 177-86. PMID 10854928 DOI: 10.1016/S0031-9384(00)00200-6 |
1 |
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1999 |
Neylon CB, Lang RJ, Fu Y, Bobik A, Reinhart PH. Molecular cloning and characterization of the intermediate-conductance Ca(2+)-activated K(+) channel in vascular smooth muscle: relationship between K(Ca) channel diversity and smooth muscle cell function Circulation Research. 85: e33-43. PMID 10532960 |
1 |
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1998 |
Rhodes N, D'Souza T, Foster CD, Ziv Y, Kirsch DG, Shiloh Y, Kastan MB, Reinhart PH, Gilmer TM. Defective potassium currents in ataxia telangiectasia fibroblasts Genes and Development. 12: 3686-3692. PMID 9851975 |
1 |
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1997 |
DiChiara TJ, Reinhart PH. Redox modulation of hslo Ca2+-activated K+ channels Journal of Neuroscience. 17: 4942-4955. PMID 9185532 |
1 |
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1997 |
Koschak A, Koch RO, Liu J, Kaczorowski GJ, Reinhart PH, Garcia ML, Knaus HG. [125I]iberiotoxin-D19Y/Y36F, the first selective, high specific activity radioligand for high-conductance calcium-activated potassium channels Biochemistry. 36: 1943-1952. PMID 9048582 DOI: 10.1021/bi962074m |
1 |
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1996 |
Krause JD, Foster CD, Reinhart PH. Xenopus laevis oocytes contain endogenous large conductance Ca2(+)-activated K+ channels. Neuropharmacology. 35: 1017-22. PMID 8938732 DOI: 10.1016/0028-3908(96)00134-7 |
1 |
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1996 |
Tseng-Crank J, Godinot N, Johansen TE, Ahring PK, Strøbaek D, Mertz R, Foster CD, Olesen SP, Reinhart PH. Cloning, expression, and distribution of a Ca(2+)-activated K+ channel beta-subunit from human brain. Proceedings of the National Academy of Sciences of the United States of America. 93: 9200-5. PMID 8799178 |
1 |
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1995 |
DiChiara TJ, Reinhart PH. Distinct effects of Ca2+ and voltage on the activation and deactivation of cloned Ca(2+)‐activated K+ channels The Journal of Physiology. 489: 403-418. PMID 8847636 DOI: 10.1113/jphysiol.1995.sp021061 |
1 |
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1995 |
Reinhart PH, Levitan IB. Kinase and phosphatase activities intimately associated with a reconstituted calcium-dependent potassium channel. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 15: 4572-9. PMID 7790924 |
1 |
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1994 |
McKay MC, Dworetzky SI, Meanwell NA, Olesen SP, Reinhart PH, Levitan IB, Adelman JP, Gribkoff VK. Opening of large-conductance calcium-activated potassium channels by the substituted benzimidazolone NS004. Journal of Neurophysiology. 71: 1873-82. PMID 8064354 |
1 |
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1991 |
Chung SK, Reinhart PH, Martin BL, Brautigan D, Levitan IB. Protein kinase activity closely associated with a reconstituted calcium-activated potassium channel. Science (New York, N.Y.). 253: 560-2. PMID 1857986 |
1 |
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1991 |
Reinhart PH, Chung S, Martin BL, Brautigan DL, Levitan IB. Modulation of calcium-activated potassium channels from rat brain by protein kinase A and phosphatase 2A. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 11: 1627-35. PMID 1646298 |
1 |
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1990 |
Pfeiffer B, Elmer K, Roggendorf W, Reinhart PH, Hamprecht B. Immunohistochemical demonstration of glycogen phosphorylase in rat brain slices. Histochemistry. 94: 73-80. PMID 2351562 DOI: 10.1007/BF00266792 |
1 |
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1990 |
Levitan IB, Chung S, Reinhart PH. Modulation of a single ion channel by several different protein kinases. Advances in Second Messenger and Phosphoprotein Research. 24: 36-40. PMID 1698410 |
1 |
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1990 |
Reinhart PH, Pfeiffer B, Spengler S, Hamprecht B. Purification of glycogen phosphorylase from bovine brain and immunocytochemical examination of rat glial primary cultures using monoclonal antibodies raised against this enzyme. Journal of Neurochemistry. 54: 1474-83. PMID 1691273 DOI: 10.1111/j.1471-4159.1990.tb01194.x |
1 |
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1989 |
Reinhart PH, Chung S, Levitan IB. A family of calcium-dependent potassium channels from rat brain. Neuron. 2: 1031-41. PMID 2624739 DOI: 10.1016/0896-6273(89)90227-4 |
1 |
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1988 |
MacKinnon R, Reinhart PH, White MM. Charybdotoxin block of Shaker K+ channels suggests that different types of K+ channels share common structural features. Neuron. 1: 997-1001. PMID 2483094 DOI: 10.1016/0896-6273(88)90156-0 |
1 |
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1985 |
Taylor WM, van de Pol E, van Helden DF, Reinhart PH, Bygrave FL. Effect of depolarizing concentrations of potassium on calcium uptake and metabolism in rat liver. Febs Letters. 183: 70-4. PMID 3979569 DOI: 10.1016/0014-5793(85)80956-X |
1 |
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1984 |
Reinhart PH, Taylor WM, Bygrave FL. The action of alpha-adrenergic agonists on plasma-membrane calcium fluxes in perfused rat liver. The Biochemical Journal. 220: 43-50. PMID 6743272 |
1 |
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1984 |
Reinhart PH, Taylor WM, Bygrave FL. The contribution of both extracellular and intracellular calcium to the action of alpha-adrenergic agonists in perfused rat liver. The Biochemical Journal. 220: 35-42. PMID 6743271 |
1 |
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1984 |
Reinhart PH, Taylor WM, Bygrave FL. Binding and uptake of [3H]adrenaline by perfused rat liver. The Biochemical Journal. 218: 765-73. PMID 6721833 |
1 |
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1984 |
Reinhart PH, van de Pol E, Taylor WM, Bygrave FL. An assessment of the calcium content of rat liver mitochondria in vivo. The Biochemical Journal. 218: 415-20. PMID 6201164 |
1 |
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1984 |
Bygrave FL, Epping RJ, Reinhart PH, Taylor WM, van de Pol E. Intracellular calcium and its regulation in liver. Progress in Clinical and Biological Research. 168: 109-16. PMID 6151186 |
1 |
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1984 |
Reinhart PH, Taylor WM, Bygrave FL. The mechanism of alpha-adrenergic agonist action in liver. Biological Reviews of the Cambridge Philosophical Society. 59: 511-57. PMID 6150731 |
1 |
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1984 |
Reinhart PH, Taylor WM, Bygrave FL. The role of calcium ions in the mechanism of action of alpha-adrenergic agonists in rat liver. The Biochemical Journal. 223: 1-13. PMID 6149742 |
1 |
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1983 |
Taylor WM, Reinhart PH, Bygrave FL. Stimulation by alpha-adrenergic agonists of Ca2+ fluxes, mitochondrial oxidation and gluconeogenesis in perfused rat liver. The Biochemical Journal. 212: 555-65. PMID 6882384 |
1 |
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1983 |
Reinhart PH, Taylor WM, Bygrave FL. The effect of ionophore A23187 on calcium ion fluxes and alpha-adrenergic-agonist action in perfused rat liver. The Biochemical Journal. 214: 405-12. PMID 6412701 |
1 |
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1983 |
Taylor WM, Reinhart PH, Bygrave FL. On the role of calcium in the mechanism of action of alpha-adrenergic agonists in rat liver. Pharmacology & Therapeutics. 21: 125-41. PMID 6137843 DOI: 10.1016/0163-7258(83)90070-0 |
1 |
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1982 |
Reinhart PH, Taylor WM, Bygrave FL. A procedure for the rapid preparation of mitochondria from rat liver. The Biochemical Journal. 204: 731-5. PMID 7126163 |
1 |
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1982 |
Reinhart PH, Taylor WM, Bygrave FL. Studies on alpha-adrenergic-induced respiration and glycogenolysis in perfused rat liver. The Journal of Biological Chemistry. 257: 1906-12. PMID 7056751 |
1 |
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1982 |
Reinhart PH, Taylor WM, Bygrave FL. Calcium ion fluxes induced by the action of alpha-adrenergic agonists in perfused rat liver. The Biochemical Journal. 208: 619-30. PMID 6131669 |
1 |
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1981 |
Reinhart PH, Bygrave FL. Glucagon stimulation of Ruthenium Red-insensitive calcium ion transport in developing rat liver Biochemical Journal. 194: 541-549. PMID 6171260 |
1 |
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1981 |
Reinhart PH, Taylor WM, Bygrave FL. Early metabolic responses to α-adrenergic agonists may involve calmodulin Biochemical Society Transactions. 9. |
1 |
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1981 |
Reinhart PH, Taylor WM, Bygrave FL. The action of anti-psychotic agents in inhibiting α-adrenergic agonist induced hepatic metabolic responses Biochemistry International. 2: 437-445. |
1 |
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1980 |
Reinhart PH, Taylor WM, Bygrave FL. Trifluoperazine, an inhibitor of calmodulin action, antagonises phenylephrine-induced metabolic responses and mitochondrial calcium fluxes in liver. Febs Letters. 120: 71-4. PMID 7439392 DOI: 10.1016/0014-5793(80)81049-0 |
1 |
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