Year |
Citation |
Score |
2023 |
Sangadi DK, Sangadi A, Placeres-Uray F, Titus DJ, Johnstone T, Hogenkamp D, Gee KW, Atkins CM. Enhancing cognitive function in chronic TBI: The Role of α7 nicotinic acetylcholine receptor modulation. Experimental Neurology. 372: 114647. PMID 38070724 DOI: 10.1016/j.expneurol.2023.114647 |
0.602 |
|
2019 |
Titus DJ, Johnstone T, Johnson NH, London SH, Chapalamadugu M, Hogenkamp D, Gee KW, Atkins CM. Positive allosteric modulation of the α7 nicotinic acetylcholine receptor as a treatment for cognitive deficits after traumatic brain injury. Plos One. 14: e0223180. PMID 31581202 DOI: 10.1371/Journal.Pone.0223180 |
0.642 |
|
2018 |
Reddy DS, Yoshimura RF, Ramanathan G, Carver C, Johnstone TB, Hogenkamp DJ, Gee KW. Role of β-specific GABA-A receptor isoforms in the development of hippocampus kindling epileptogenesis. Epilepsy & Behavior : E&B. 82: 57-63. PMID 29587186 DOI: 10.1016/J.Yebeh.2018.02.020 |
0.805 |
|
2017 |
Yoshimura RF, Tran MB, Hogenkamp DJ, Ayala NL, Johnstone T, Dunnigan AJ, Gee TK, Gee KW. Allosteric modulation of nicotinic and GABAA receptor subtypes differentially modify autism-like behaviors in the BTBR mouse model. Neuropharmacology. PMID 28842344 DOI: 10.1016/J.Neuropharm.2017.08.029 |
0.785 |
|
2017 |
Gee KW, Olincy A, Kanner R, Johnson L, Hogenkamp D, Harris J, Tran M, Edmonds SA, Sauer W, Yoshimura R, Johnstone T, Freedman R. First in human trial of a type I positive allosteric modulator of alpha7-nicotinic acetylcholine receptors: Pharmacokinetics, safety, and evidence for neurocognitive effect of AVL-3288. Journal of Psychopharmacology (Oxford, England). 269881117691590. PMID 28196430 DOI: 10.1177/0269881117691590 |
0.782 |
|
2015 |
Dasse O, Bilcer G, Putman D, Ng R, Gee K, Stevens KE, Tran M, Johnstone T, Yoshimura RF, Koelsch G, Kelly TA. APN0417: A potent and efficacious α7 nAChR positive allosteric modulator Biochemical Pharmacology. 97: 636. DOI: 10.1016/J.Bcp.2015.08.043 |
0.781 |
|
2015 |
Titus DJ, Concepcion F, Johnstone T, Hogenkamp D, Gee KW, Atkins CM. Positive allosteric modulation of the α7 nicotinic acetylcholine receptor reverses chronic cognitive deficits after TBI Biochemical Pharmacology. 97: 635. DOI: 10.1016/J.Bcp.2015.08.041 |
0.683 |
|
2014 |
Hogenkamp DJ, Tran MB, Yoshimura RF, Johnstone TB, Kanner R, Gee KW. Pharmacological profile of a 17β-heteroaryl-substituted neuroactive steroid. Psychopharmacology. 231: 3517-24. PMID 24682501 DOI: 10.1007/S00213-014-3494-5 |
0.743 |
|
2014 |
Yoshimura RF, Tran MB, Hogenkamp DJ, Johnstone TB, Xie JY, Porreca F, Gee KW. Limited central side effects of a β-subunit subtype-selective GABAA receptor allosteric modulator. Journal of Psychopharmacology (Oxford, England). 28: 472-8. PMID 24108410 DOI: 10.1177/0269881113507643 |
0.807 |
|
2013 |
Hogenkamp DJ, Ford-Hutchinson TA, Li WY, Whittemore ER, Yoshimura RF, Tran MB, Johnstone TB, Bascom GD, Rollins H, Lu L, Gee KW. Design, synthesis, and activity of a series of arylpyrid-3-ylmethanones as type I positive allosteric modulators of α7 nicotinic acetylcholine receptors. Journal of Medicinal Chemistry. 56: 8352-65. PMID 24098954 DOI: 10.1021/Jm400704G |
0.804 |
|
2012 |
Chen S, Tusty M, Johnstone T, Hogenkamp D, Gee K, Brinton R. P2-395: Allopregnanolone analogues promote proliferation of neural progenitor cells Alzheimer's & Dementia. 8: P401-P401. DOI: 10.1016/J.Jalz.2012.05.1105 |
0.534 |
|
2011 |
Johnstone TB, Gu Z, Yoshimura RF, Villegier AS, Hogenkamp DJ, Whittemore ER, Huang JC, Tran MB, Belluzzi JD, Yakel JL, Gee KW. Allosteric modulation of related ligand-gated ion channels synergistically induces long-term potentiation in the hippocampus and enhances cognition. The Journal of Pharmacology and Experimental Therapeutics. 336: 908-15. PMID 21159751 DOI: 10.1124/Jpet.110.176255 |
0.79 |
|
2011 |
Carboni E, Ibba M, Cadeddu R, Hogenkamp D, Johnstone T, Gee K. The α7 nicotinic acetylcholine receptor (nAChR) allosteric modulator UCI-40083 differentially increases dopamine (DA) and norepinephrine (NE) release in adolescent rat brain Biochemical Pharmacology. 82: 1042-1043. DOI: 10.1016/J.Bcp.2011.07.051 |
0.371 |
|
2010 |
Gee KW, Tran MB, Hogenkamp DJ, Johnstone TB, Bagnera RE, Yoshimura RF, Huang JC, Belluzzi JD, Whittemore ER. Limiting activity at beta1-subunit-containing GABAA receptor subtypes reduces ataxia. The Journal of Pharmacology and Experimental Therapeutics. 332: 1040-53. PMID 19940102 DOI: 10.1124/Jpet.109.161885 |
0.698 |
|
2009 |
Gee K, Hogenkamp D, Johnstone T. Dual allosteric modulators of neuronal nicotinic-acetylcholine and GABAA receptors Biochemical Pharmacology. 78: 913-914. DOI: 10.1016/J.Bcp.2009.06.065 |
0.665 |
|
2007 |
Hogenkamp DJ, Johnstone TB, Huang JC, Li WY, Tran M, Whittemore ER, Bagnera RE, Gee KW. Enaminone amides as novel orally active GABAA receptor modulators. Journal of Medicinal Chemistry. 50: 3369-79. PMID 17571865 DOI: 10.1021/Jm070083V |
0.742 |
|
2007 |
Ng HJ, Whittemore ER, Tran MB, Hogenkamp DJ, Broide RS, Johnstone TB, Zheng L, Stevens KE, Gee KW. Nootropic alpha7 nicotinic receptor allosteric modulator derived from GABAA receptor modulators. Proceedings of the National Academy of Sciences of the United States of America. 104: 8059-64. PMID 17470817 DOI: 10.1073/Pnas.0701321104 |
0.768 |
|
2006 |
Wang J, Hogenkamp DJ, Tran M, Li WY, Yoshimura RF, Johnstone TB, Shen WC, Gee KW. Reversible lipidization for the oral delivery of leu-enkephalin. Journal of Drug Targeting. 14: 127-36. PMID 16753826 DOI: 10.1080/10611860600648221 |
0.738 |
|
2004 |
Johnstone TB, Hogenkamp DJ, Coyne L, Su J, Halliwell RF, Tran MB, Yoshimura RF, Li WY, Wang J, Gee KW. Modifying quinolone antibiotics yields new anxiolytics. Nature Medicine. 10: 31-2. PMID 14647497 DOI: 10.1038/Nm967 |
0.786 |
|
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