Diego Sepulveda-Falla, M.D. - Publications

Affiliations: 
Institute of Neuropathology UKE Hamburg 
Area:
Alzheimer

36 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Wasilewski D, Villalba-Moreno ND, Stange I, Glatzel M, Sepulveda-Falla D, Krasemann S. Reactive Astrocytes Contribute to Alzheimer's Disease-Related Neurotoxicity and Synaptotoxicity in a Neuron-Astrocyte Co-culture Assay. Frontiers in Cellular Neuroscience. 15: 739411. PMID 35126055 DOI: 10.3389/fncel.2021.739411  0.509
2022 Krasemann S, Haferkamp U, Pfefferle S, Woo MS, Heinrich F, Schweizer M, Appelt-Menzel A, Cubukova A, Barenberg J, Leu J, Hartmann K, Thies E, Littau JL, Sepulveda-Falla D, Zhang L, et al. The blood-brain barrier is dysregulated in COVID-19 and serves as a CNS entry route for SARS-CoV-2. Stem Cell Reports. PMID 35063125 DOI: 10.1016/j.stemcr.2021.12.011  0.448
2021 Kalaria RN, Sepulveda-Falla D. Cerebral Small Vessel Disease in Sporadic and Familial Alzheimer Disease. The American Journal of Pathology. PMID 34331941 DOI: 10.1016/j.ajpath.2021.07.004  0.396
2021 O'Hare M, Amarnani D, Whitmore HAB, An M, Marino C, Ramos L, Delgado-Tirado S, Hu X, Chmielewska N, Chandrahas A, Fitzek A, Heinrich F, Steurer S, Ondruschka B, Glatzel M, ... ... Sepulveda-Falla D, et al. Targeting RUNX1 prevents pulmonary fibrosis and reduces expression of SARS-CoV-2 host mediators. The American Journal of Pathology. PMID 33894177 DOI: 10.1016/j.ajpath.2021.04.006  0.413
2020 Sepulveda-Falla D, Chavez-Gutierrez L, Portelius E, Vélez JI, Dujardin S, Barrera-Ocampo A, Dinkel F, Hagel C, Puig B, Mastronardi C, Lopera F, Hyman BT, Blennow K, Arcos-Burgos M, de Strooper B, et al. A multifactorial model of pathology for age of onset heterogeneity in familial Alzheimer's disease. Acta Neuropathologica. PMID 33319314 DOI: 10.1007/s00401-020-02249-0  0.783
2020 Podlesniy P, Llorens F, Puigròs M, Serra N, Sepúlveda-Falla D, Schmidt C, Hermann P, Zerr I, Trullas R. Cerebrospinal Fluid Mitochondrial DNA in Rapid and Slow Progressive Forms of Alzheimer's Disease. International Journal of Molecular Sciences. 21. PMID 32878083 DOI: 10.3390/Ijms21176298  0.451
2020 Dinkel F, Trujillo-Rodriguez D, Villegas A, Streffer J, Mercken M, Lopera F, Glatzel M, Sepulveda-Falla D. Decreased Deposition of Beta-Amyloid 1-38 and Increased Deposition of Beta-Amyloid 1-42 in Brain Tissue of Presenilin-1 E280A Familial Alzheimer's Disease Patients. Frontiers in Aging Neuroscience. 12: 220. PMID 32848702 DOI: 10.3389/Fnagi.2020.00220  0.663
2020 Palmqvist S, Janelidze S, Quiroz YT, Zetterberg H, Lopera F, Stomrud E, Su Y, Chen Y, Serrano GE, Leuzy A, Mattsson-Carlgren N, Strandberg O, Smith R, Villegas A, Sepulveda-Falla D, et al. Discriminative Accuracy of Plasma Phospho-tau217 for Alzheimer Disease vs Other Neurodegenerative Disorders. Jama. PMID 32722745 DOI: 10.1001/Jama.2020.12134  0.603
2020 Quiroz YT, Zetterberg H, Reiman EM, Chen Y, Su Y, Fox-Fuller JT, Garcia G, Villegas A, Sepulveda-Falla D, Villada M, Arboleda-Velasquez JF, Guzmán-Vélez E, Vila-Castelar C, Gordon BA, Schultz SA, et al. Plasma neurofilament light chain in the presenilin 1 E280A autosomal dominant Alzheimer's disease kindred: a cross-sectional and longitudinal cohort study. The Lancet. Neurology. 19: 513-521. PMID 32470423 DOI: 10.1016/S1474-4422(20)30137-X  0.55
2020 Sabogal-Guáqueta AM, Arias-Londoño JD, Gutierrez-Vargas J, Sepulveda-Falla D, Glatzel M, Villegas-Lanau A, Cardona-Gómez GP. Common disbalance in the brain parenchyma of dementias: Phospholipid profile analysis between CADASIL and sporadic Alzheimer's disease. Biochimica Et Biophysica Acta. Molecular Basis of Disease. 1866: 165797. PMID 32302650 DOI: 10.1016/J.Bbadis.2020.165797  0.572
2020 Rojas-Charry L, Calero-Martinez S, Morganti C, Morciano G, Park K, Hagel C, Marciniak SJ, Glatzel M, Pinton P, Sepulveda-Falla D. Susceptibility to cellular stress in PS1 mutant N2a cells is associated with mitochondrial defects and altered calcium homeostasis. Scientific Reports. 10: 6455. PMID 32296078 DOI: 10.1038/S41598-020-63254-7  0.53
2019 Hermann M, Reumann R, Schostak K, Kement D, Gelderblom M, Bernreuther C, Frischknecht R, Schipanski A, Marik S, Krasemann S, Sepulveda-Falla D, Schweizer M, Magnus T, Glatzel M, Galliciotti G. Deficits in developmental neurogenesis and dendritic spine maturation in mice lacking the serine protease inhibitor neuroserpin. Molecular and Cellular Neurosciences. 102: 103420. PMID 31805346 DOI: 10.1016/J.Mcn.2019.103420  0.511
2019 Muth C, Hartmann A, Sepulveda-Falla D, Glatzel M, Krasemann S. Phagocytosis of Apoptotic Cells Is Specifically Upregulated in ApoE4 Expressing Microglia . Frontiers in Cellular Neuroscience. 13: 181. PMID 31130847 DOI: 10.3389/Fncel.2019.00181  0.634
2019 Hartmann K, Sepulveda-Falla D, Rose IVL, Madore C, Muth C, Matschke J, Butovsky O, Liddelow S, Glatzel M, Krasemann S. Complement 3-astrocytes are highly abundant in prion diseases, but their abolishment led to an accelerated disease course and early dysregulation of microglia. Acta Neuropathologica Communications. 7: 83. PMID 31118110 DOI: 10.1186/S40478-019-0735-1  0.546
2019 Arcos-Burgos M, Lopera F, Sepulveda-Falla D, Mastronardi C. Neural Plasticity during Aging. Neural Plasticity. 2019: 6042132. PMID 31049053 DOI: 10.1155/2019/6042132  0.491
2019 Sepulveda-Falla D, Villegas A, Lopera F, Glatzel M. The Colombian-German network for neurodegenerative research: UndoAD. The Lancet. Neurology. 18: 29. PMID 30563680 DOI: 10.1016/S1474-4422(18)30458-7  0.568
2018 Krbot K, Hermann P, Skorić MK, Zerr I, Sepulveda-Falla D, Goebel S, Matschke J, Krasemann S, Glatzel M. Distinct microglia profile in Creutzfeldt-Jakob disease and Alzheimer's disease is independent of disease kinetics. Neuropathology : Official Journal of the Japanese Society of Neuropathology. PMID 30318820 DOI: 10.1111/Neup.12517  0.605
2017 Rasmussen J, Mahler J, Beschorner N, Kaeser SA, Häsler LM, Baumann F, Nyström S, Portelius E, Blennow K, Lashley T, Fox NC, Sepulveda-Falla D, Glatzel M, Oblak AL, Ghetti B, et al. Amyloid polymorphisms constitute distinct clouds of conformational variants in different etiological subtypes of Alzheimer's disease. Proceedings of the National Academy of Sciences of the United States of America. PMID 29158413 DOI: 10.1073/Pnas.1713215114  0.639
2016 Vélez JI, Lopera F, Patel HR, Johar AS, Cai Y, Rivera D, Tobón C, Villegas A, Sepulveda-Falla D, Lehmann SG, Easteal S, Mastronardi CA, Arcos-Burgos M. Mutations modifying sporadic Alzheimer's disease age of onset. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. PMID 27573710 DOI: 10.1002/Ajmg.B.32493  0.491
2016 Barrera-Ocampo A, Arlt S, Matschke J, Hartmann U, Puig B, Ferrer I, Zürbig P, Glatzel M, Sepulveda-Falla D, Jahn H. Amyloid-β Precursor Protein Modulates the Sorting of Testican-1 and Contributes to Its Accumulation in Brain Tissue and Cerebrospinal Fluid from Patients with Alzheimer Disease. Journal of Neuropathology and Experimental Neurology. PMID 27486134 DOI: 10.1093/Jnen/Nlw065  0.779
2016 Glatzel M, Sepulveda-Falla D. Losing sleep over mitochondria: A new player in the pathophysiology of Fatal Familial Insomnia. Brain Pathology (Zurich, Switzerland). PMID 27350067 DOI: 10.1111/Bpa.12410  0.51
2015 Friedrich C, von Bueren AO, Kolevatova L, Bernreuther C, Grob T, Sepulveda-Falla D, van den Boom L, Westphal M, Simon R, Glatzel M. Epidermal growth factor receptor overexpression is common and not correlated to gene copy number in ependymoma. Child's Nervous System : Chns : Official Journal of the International Society For Pediatric Neurosurgery. PMID 26686534 DOI: 10.1007/S00381-015-2981-2  0.458
2015 Vélez JI, Lopera F, Sepulveda-Falla D, Patel HR, Johar AS, Chuah A, Tobón C, Rivera D, Villegas A, Cai Y, Peng K, Arkell R, Castellanos FX, Andrews SJ, Silva Lara MF, et al. APOE*E2 allele delays age of onset in PSEN1 E280A Alzheimer's disease. Molecular Psychiatry. PMID 26619808 DOI: 10.1038/Mp.2015.177  0.582
2015 Szaruga M, Veugelen S, Benurwar M, Lismont S, Sepulveda-Falla D, Lleo A, Ryan NS, Lashley T, Fox NC, Murayama S, Gijsen H, De Strooper B, Chávez-Gutiérrez L. Qualitative changes in human γ-secretase underlie familial Alzheimer's disease. The Journal of Experimental Medicine. PMID 26481686 DOI: 10.1084/Jem.20150892  0.519
2014 Sepulveda-Falla D, Barrera-Ocampo A, Hagel C, Korwitz A, Vinueza-Veloz MF, Zhou K, Schonewille M, Zhou H, Velazquez-Perez L, Rodriguez-Labrada R, Villegas A, Ferrer I, Lopera F, Langer T, De Zeeuw CI, et al. Familial Alzheimer's disease-associated presenilin-1 alters cerebellar activity and calcium homeostasis. The Journal of Clinical Investigation. 124: 1552-67. PMID 24569455 DOI: 10.1172/Jci66407  0.758
2014 Dohler F, Sepulveda-Falla D, Krasemann S, Altmeppen H, Schlüter H, Hildebrand D, Zerr I, Matschke J, Glatzel M. High molecular mass assemblies of amyloid-β oligomers bind prion protein in patients with Alzheimer's disease. Brain : a Journal of Neurology. 137: 873-86. PMID 24519981 DOI: 10.1093/Brain/Awt375  0.609
2014 Bogner S, Bernreuther C, Matschke J, Barrera-Ocampo A, Sepulveda-Falla D, Leypoldt F, Magnus T, Haag F, Bergmann M, Brück W, Vogelgesang S, Glatzel M. Immune activation in amyloid-β-related angiitis correlates with decreased parenchymal amyloid-β plaque load. Neuro-Degenerative Diseases. 13: 38-44. PMID 24021982 DOI: 10.1159/000352020  0.744
2014 Trujillo-Rodríguez DM, Sepúlveda-Falla D, Arboleda H, Glatzel M, Lopera F. Neuropathological, Neuropsychological, And Imagenological Comparison Between Sporadic Alzheimer'S Disease And Ps1-E280A Alzheimers & Dementia. 10: 476. DOI: 10.1016/J.Jalz.2014.05.689  0.684
2013 Castro-Gomez S, Barrera-Ocampo A, Machado-Rodriguez G, Castro-Alvarez JF, Glatzel M, Giraldo M, Sepulveda-Falla D. Specific de-SUMOylation triggered by acquisition of spatial learning is related to epigenetic changes in the rat hippocampus. Neuroreport. 24: 976-81. PMID 24089016 DOI: 10.1097/Wnr.0000000000000025  0.713
2013 Pera M, Alcolea D, Sánchez-Valle R, Guardia-Laguarta C, Colom-Cadena M, Badiola N, Suárez-Calvet M, Lladó A, Barrera-Ocampo AA, Sepulveda-Falla D, Blesa R, Molinuevo JL, Clarimón J, Ferrer I, Gelpi E, et al. Distinct patterns of APP processing in the CNS in autosomal-dominant and sporadic Alzheimer disease. Acta Neuropathologica. 125: 201-13. PMID 23224319 DOI: 10.1007/S00401-012-1062-9  0.781
2012 Sepulveda-Falla D, Glatzel M, Lopera F. Phenotypic profile of early-onset familial Alzheimer's disease caused by presenilin-1 E280A mutation. Journal of Alzheimer's Disease : Jad. 32: 1-12. PMID 22766738 DOI: 10.3233/Jad-2012-120907  0.69
2011 Acosta-Baena N, Sepulveda-Falla D, Lopera-Gómez CM, Jaramillo-Elorza MC, Moreno S, Aguirre-Acevedo DC, Saldarriaga A, Lopera F. Pre-dementia clinical stages in presenilin 1 E280A familial early-onset Alzheimer's disease: a retrospective cohort study. The Lancet. Neurology. 10: 213-20. PMID 21296022 DOI: 10.1016/S1474-4422(10)70323-9  0.491
2011 Sepulveda-Falla D, Matschke J, Bernreuther C, Hagel C, Puig B, Villegas A, Garcia G, Zea J, Gomez-Mancilla B, Ferrer I, Lopera F, Glatzel M. Deposition of hyperphosphorylated tau in cerebellum of PS1 E280A Alzheimer's disease. Brain Pathology (Zurich, Switzerland). 21: 452-63. PMID 21159009 DOI: 10.1111/J.1750-3639.2010.00469.X  0.704
2010 Moreno S, Garcia G, Saldarriaga A, Sepulveda-Falla D, Arboleda J, Kosik K, Lopera F. Genotype - phenotype correlation in CADASIL. Cognitive performance in carriers of notch3 mutations R1031C and C455R International Journal of Psychological Research. 3: 109-122. DOI: 10.21500/20112084.817  0.491
2006 Pineda-Trujillo N, Apergi M, Moreno S, Arias W, Lesage S, Franco A, Sepulveda-Falla D, Cano D, Buriticá O, Pineda D, Uribe CS, de Yebenes JG, Lees AJ, Brice A, Bedoya G, et al. A genetic cluster of early onset Parkinson's disease in a Colombian population. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 141: 885-9. PMID 16941654 DOI: 10.1002/Ajmg.B.30375  0.523
2002 Arboleda-Velasquez JF, Lopera F, Lopez E, Frosch MP, Sepulveda-Falla D, Gutierrez JE, Vargas S, Medina M, Martinez De Arrieta C, Lebo RV, Slaugenhaupt SA, Betensky RA, Villegas A, Arcos-Burgos M, Rivera D, et al. C455R notch3 mutation in a Colombian CADASIL kindred with early onset of stroke. Neurology. 59: 277-9. PMID 12136071 DOI: 10.1212/Wnl.59.2.277  0.508
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