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Feng Zhang, Ph.D. - Publications

Affiliations: 
2011- Biological Engineering Massachusetts Institute of Technology, Cambridge, MA, United States 
Website:
https://be.mit.edu/directory/feng-zhang

239 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Kannan S, Altae-Tran H, Jin X, Madigan VJ, Oshiro R, Makarova KS, Koonin EV, Zhang F. Compact RNA editors with small Cas13 proteins. Nature Biotechnology. PMID 34462587 DOI: 10.1038/s41587-021-01030-2  0.343
2021 Segel M, Lash B, Song J, Ladha A, Liu CC, Jin X, Mekhedov SL, Macrae RK, Koonin EV, Zhang F. Mammalian retrovirus-like protein PEG10 packages its own mRNA and can be pseudotyped for mRNA delivery. Science (New York, N.Y.). 373: 882-889. PMID 34413232 DOI: 10.1126/science.abg6155  0.363
2021 McCabe SD, Hammershaimb EA, Cheng D, Shi A, Shyr D, Shen S, Cole LD, Cataldi JR, Allen W, Probasco R, Silbermann B, Zhang F, Marsh R, Travassos MA, Lin X. Unraveling Attributes of COVID-19 Vaccine Hesitancy in the U.S.: A Large Nationwide Study. Medrxiv : the Preprint Server For Health Sciences. PMID 33851172 DOI: 10.1101/2021.04.05.21254918  0.415
2021 Qiu M, Glass Z, Chen J, Haas M, Jin X, Zhao X, Rui X, Ye Z, Li Y, Zhang F, Xu Q. Lipid nanoparticle-mediated codelivery of Cas9 mRNA and single-guide RNA achieves liver-specific in vivo genome editing of . Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 33649229 DOI: 10.1073/pnas.2020401118  0.47
2021 Madison JM, Duong K, Vieux EF, Udeshi ND, Iqbal S, Requadt E, Fereshetian S, Lewis MC, Gomes AS, Pierce KA, Platt RJ, Zhang F, Campbell AJ, Lal D, Wagner FF, et al. Regulation of purine metabolism connects KCTD13 to a metabolic disorder with autistic features. Iscience. 24: 101935. PMID 33409479 DOI: 10.1016/j.isci.2020.101935  0.692
2020 Jin X, Simmons SK, Guo A, Shetty AS, Ko M, Nguyen L, Jokhi V, Robinson E, Oyler P, Curry N, Deangeli G, Lodato S, Levin JZ, Regev A, Zhang F, et al. In vivo Perturb-Seq reveals neuronal and glial abnormalities associated with autism risk genes. Science (New York, N.Y.). 370. PMID 33243861 DOI: 10.1126/science.aaz6063  0.651
2020 Angrist M, Barrangou R, Baylis F, Brokowski C, Burgio G, Caplan A, Chapman CR, Church GM, Cook-Deegan R, Cwik B, Doudna JA, Evans JH, Greely HT, Hercher L, Hurlbut JB, ... ... Zhang F, et al. Reactions to the National Academies/Royal Society Report on . The Crispr Journal. 3: 332-349. PMID 33095048 DOI: 10.1089/crispr.2020.29106.man  0.509
2020 Gao L, Altae-Tran H, Böhning F, Makarova KS, Segel M, Schmid-Burgk JL, Koob J, Wolf YI, Koonin EV, Zhang F. Diverse enzymatic activities mediate antiviral immunity in prokaryotes. Science (New York, N.Y.). 369: 1077-1084. PMID 32855333 DOI: 10.1126/Science.Aba0372  0.337
2020 Allen WE, Altae-Tran H, Briggs J, Jin X, McGee G, Shi A, Raghavan R, Kamariza M, Nova N, Pereta A, Danford C, Kamel A, Gothe P, Milam E, Aurambault J, ... ... Zhang F, et al. Population-scale longitudinal mapping of COVID-19 symptoms, behaviour and testing. Nature Human Behaviour. PMID 32848231 DOI: 10.1038/S41562-020-00944-2  0.555
2020 Patchsung M, Jantarug K, Pattama A, Aphicho K, Suraritdechachai S, Meesawat P, Sappakhaw K, Leelahakorn N, Ruenkam T, Wongsatit T, Athipanyasilp N, Eiamthong B, Lakkanasirorat B, Phoodokmai T, Niljianskul N, ... ... Zhang F, et al. Clinical validation of a Cas13-based assay for the detection of SARS-CoV-2 RNA. Nature Biomedical Engineering. PMID 32848209 DOI: 10.1038/S41551-020-00603-X  0.382
2020 MacKay MJ, Hooker AC, Afshinnekoo E, Salit M, Kelly J, Feldstein JV, Haft N, Schenkel D, Nambi S, Cai Y, Zhang F, Church G, Dai J, Wang CL, Levy S, et al. The COVID-19 XPRIZE and the need for scalable, fast, and widespread testing. Nature Biotechnology. PMID 32820257 DOI: 10.1038/S41587-020-0655-4  0.528
2020 Weiss T, Wang C, Kang X, Zhao H, Gamo ME, Starker CG, Crisp PA, Zhou P, Springer NM, Voytas DF, Zhang F. Optimization of multiplexed CRISPR/Cas9 system for highly efficient genome editing in Setaria viridis. The Plant Journal : For Cell and Molecular Biology. PMID 32786122 DOI: 10.1111/Tpj.14949  0.344
2020 Jin S, Fei H, Zhu Z, Luo Y, Liu J, Gao S, Zhang F, Chen YH, Wang Y, Gao C. Rationally Designed APOBEC3B Cytosine Base Editors with Improved Specificity. Molecular Cell. PMID 32721385 DOI: 10.1016/J.Molcel.2020.07.005  0.35
2020 Segal E, Zhang F, Lin X, King G, Shalem O, Shilo S, Allen WE, Alquaddoomi F, Altae-Tran H, Anders S, Balicer R, Bauman T, Bonilla X, Booman G, Chan AT, et al. Publisher Correction: Building an international consortium for tracking coronavirus health status. Nature Medicine. PMID 32591764 DOI: 10.1038/S41591-020-0983-4  0.64
2020 Allen WE, Altae-Tran H, Briggs J, Jin X, McGee G, Raghavan R, Shi A, Kamariza M, Nova N, Pereta A, Danford C, Kamel A, Gothe P, Milam E, Aurambault J, ... ... Zhang F, et al. Population-scale Longitudinal Mapping of COVID-19 Symptoms, Behavior, and Testing Identifies Contributors to Continued Disease Spread in the United States. Medrxiv : the Preprint Server For Health Sciences. PMID 32577674 DOI: 10.1101/2020.06.09.20126813  0.515
2020 Segal E, Zhang F, Lin X, King G, Shalem O, Shilo S, Allen WE, Alquaddoomi F, Altae-Tran H, Anders S, Balicer R, Bauman T, Bonilla X, Booman G, Chan AT, et al. Building an international consortium for tracking coronavirus health status. Nature Medicine. PMID 32488218 DOI: 10.1038/S41591-020-0929-X  0.646
2020 Wang D, Zhang F, Gao G. CRISPR-Based Therapeutic Genome Editing: Strategies and In Vivo Delivery by AAV Vectors. Cell. 181: 136-150. PMID 32243786 DOI: 10.1016/J.Cell.2020.03.023  0.311
2020 Schmid-Burgk JL, Gao L, Li D, Gardner Z, Strecker J, Lash B, Zhang F. Highly Parallel Profiling of Cas9 Variant Specificity. Molecular Cell. PMID 32187529 DOI: 10.1016/J.Molcel.2020.02.023  0.361
2020 Sun X, Ding Y, Orr MC, Zhang F. Streamlining universal single-copy ortholog and ultraconserved element design: a case study in Collembola. Molecular Ecology Resources. PMID 32065730 DOI: 10.1111/1755-0998.13146  0.348
2019 Makarova KS, Wolf YI, Iranzo J, Shmakov SA, Alkhnbashi OS, Brouns SJJ, Charpentier E, Cheng D, Haft DH, Horvath P, Moineau S, Mojica FJM, Scott D, Shah SA, Siksnys V, ... ... Zhang F, et al. Evolutionary classification of CRISPR-Cas systems: a burst of class 2 and derived variants. Nature Reviews. Microbiology. PMID 31857715 DOI: 10.1038/S41579-019-0299-X  0.398
2019 Zetsche B, Strecker J, Abudayyeh OO, Gootenberg JS, Scott DA, Zhang F. A Survey of Genome Editing Activity for 16 Cas12a Orthologs. The Keio Journal of Medicine. PMID 31723075 DOI: 10.2302/Kjm.2019-0009-Oa  0.493
2019 Huo X, Ji L, Zhang Y, Lv P, Cao X, Wang Q, Yan Z, Dong S, Du D, Zhang F, Wei G, Liu Y, Wen B. The Nuclear Matrix Protein SAFB Cooperates with Major Satellite RNAs to Stabilize Heterochromatin Architecture Partially through Phase Separation. Molecular Cell. PMID 31677973 DOI: 10.1016/J.Molcel.2019.10.001  0.312
2019 Feldman D, Singh A, Schmid-Burgk JL, Carlson RJ, Mezger A, Garrity AJ, Zhang F, Blainey PC. Optical Pooled Screens in Human Cells. Cell. 179: 787-799.e17. PMID 31626775 DOI: 10.1016/J.Cell.2019.09.016  0.306
2019 Yang X, Zhang X, Jiao J, Zhang F, Pan Y, Wang Q, Chen Q, Cai B, Tang S, Zhou Z, Chen S, Yin H, Fu W, Luo Y, Li D, et al. Rare variants in FANCA induce premature ovarian insufficiency. Human Genetics. PMID 31535215 DOI: 10.1007/S00439-019-02059-9  0.301
2019 Hijazi H, Coelho FS, Gonzaga-Jauregui C, Bernardini L, Mar SS, Manning MA, Hanson-Kahn A, Naidu S, Srivastava S, Lee JA, Jones JR, Friez MJ, Alberico T, Torres B, Fang P, ... Zhang F, et al. Xq22 deletions and correlation with distinct neurological disease traits in females: further evidence for a contiguous gene syndrome. Human Mutation. PMID 31448840 DOI: 10.1002/Humu.23902  0.324
2019 Engreitz J, Abudayyeh O, Gootenberg J, Zhang F. CRISPR Tools for Systematic Studies of RNA Regulation. Cold Spring Harbor Perspectives in Biology. 11. PMID 31371352 DOI: 10.1101/Cshperspect.A035386  0.316
2019 Strecker J, Ladha A, Gardner Z, Schmid-Burgk JL, Makarova KS, Koonin EV, Zhang F. RNA-guided DNA insertion with CRISPR-associated transposases. Science (New York, N.Y.). PMID 31171706 DOI: 10.1126/Science.Aax9181  0.308
2019 Hirano S, Abudayyeh OO, Gootenberg JS, Horii T, Ishitani R, Hatada I, Zhang F, Nishimasu H, Nureki O. Structural basis for the promiscuous PAM recognition by Corynebacterium diphtheriae Cas9. Nature Communications. 10: 1968. PMID 31036811 DOI: 10.1038/s41467-019-09741-6  0.31
2019 Jin S, Zong Y, Gao Q, Zhu Z, Wang Y, Qin P, Liang C, Wang D, Qiu JL, Zhang F, Gao C. Cytosine, but not adenine, base editors induce genome-wide off-target mutations in rice. Science (New York, N.Y.). PMID 30819931 DOI: 10.1126/Science.Aaw7166  0.362
2019 Strecker J, Jones S, Koopal B, Schmid-Burgk J, Zetsche B, Gao L, Makarova KS, Koonin EV, Zhang F. Engineering of CRISPR-Cas12b for human genome editing. Nature Communications. 10: 212. PMID 30670702 DOI: 10.1038/S41467-018-08224-4  0.365
2019 Zhang F, Ding Y, Zhou QS, Wu J, Luo A, Zhu CD. A high-quality draft genome assembly of Sinella curviseta, a soil model organism (Collembola). Genome Biology and Evolution. PMID 30668671 DOI: 10.1093/Gbe/Evz013  0.321
2019 Wang Q, Li D, Cai B, Chen Q, Li C, Wu Y, Jin L, Wang X, Zhang X, Zhang F. Whole-exome sequencing reveals SALL4 variants in premature ovarian insufficiency: an update on genotype-phenotype correlations. Human Genetics. PMID 30603774 DOI: 10.1007/S00439-018-1962-4  0.31
2019 Zhang F. Biology and Application of Genome Editing Blood. 134. DOI: 10.1182/Blood-2019-121282  0.319
2018 Joung J, Konermann S, Gootenberg JS, Abudayyeh OO, Platt RJ, Brigham MD, Sanjana NE, Zhang F. Author Correction: Genome-scale CRISPR-Cas9 knockout and transcriptional activation screening. Nature Protocols. PMID 30349047 DOI: 10.1038/S41596-018-0063-0  0.708
2018 Tekin H, Simmons S, Cummings B, Gao L, Adiconis X, Hession CC, Ghoshal A, Dionne D, Choudhury SR, Yesilyurt V, Sanjana NE, Shi X, Lu C, Heidenreich M, Pan JQ, ... Zhang F, et al. Effects of 3D culturing conditions on the transcriptomic profile of stem-cell-derived neurons. Nature Biomedical Engineering. 2: 540-554. PMID 30271673 DOI: 10.1038/S41551-018-0219-9  0.31
2018 Nishimasu H, Shi X, Ishiguro S, Gao L, Hirano S, Okazaki S, Noda T, Abudayyeh OO, Gootenberg JS, Mori H, Oura S, Holmes B, Tanaka M, Seki M, Hirano H, ... Zhang F, et al. Engineered CRISPR-Cas9 nuclease with expanded targeting space. Science (New York, N.Y.). PMID 30166441 DOI: 10.1126/Science.Aas9129  0.352
2018 He A, Ning Y, Wen Y, Cai Y, Xu K, Cai Y, Han J, Liu L, Du Y, Liang X, Li P, Fan Q, Hao J, Wang X, Guo X, ... Zhang F, et al. Use of integrative epigenetic and mRNA expression analyses to identify significantly changed genes and functional pathways in osteoarthritic cartilage. Bone & Joint Research. 7: 343-350. PMID 29922454 DOI: 10.1302/2046-3758.75.Bjr-2017-0284.R1  0.318
2018 Ding M, Li P, Wen Y, Zhao Y, Cheng B, Zhang L, Ma M, Cheng S, Liu L, Du Y, Liang X, He A, Guo X, Zhang F. Integrative analysis of genome-wide association study and brain region related enhancer maps identifies biological pathways for insomnia. Progress in Neuro-Psychopharmacology & Biological Psychiatry. PMID 29883697 DOI: 10.1016/J.Pnpbp.2018.05.026  0.319
2018 Myers SA, Wright J, Peckner R, Kalish BT, Zhang F, Carr SA. Discovery of proteins associated with a predefined genomic locus via dCas9-APEX-mediated proximity labeling. Nature Methods. PMID 29735997 DOI: 10.1038/S41592-018-0007-1  0.35
2018 Canver MC, Haeussler M, Bauer DE, Orkin SH, Sanjana NE, Shalem O, Yuan GC, Zhang F, Concordet JP, Pinello L. Integrated design, execution, and analysis of arrayed and pooled CRISPR genome-editing experiments. Nature Protocols. 13: 946-986. PMID 29651054 DOI: 10.1038/Nprot.2018.005  0.319
2018 Wang G, Chow RD, Ye L, Guzman CD, Dai X, Dong MB, Zhang F, Sharp PA, Platt RJ, Chen S. Mapping a functional cancer genome atlas of tumor suppressors in mouse liver using AAV-CRISPR-mediated direct in vivo screening. Science Advances. 4: eaao5508. PMID 29503867 DOI: 10.1126/Sciadv.Aao5508  0.722
2018 Zhang F, Voytas DF. Modulating gene translational control through genome editing National Science Review. 6: 391-391. DOI: 10.1093/Nsr/Nwy123  0.34
2017 Fan H, Lv P, Huo X, Wu J, Wang Q, Cheng L, Liu Y, Tang Q, Zhang L, Zhang F, Zheng X, Wu H, Wen B. The nuclear matrix protein HNRNPU maintains 3D genome architecture globally in mouse hepatocytes. Genome Research. PMID 29273625 DOI: 10.1101/Gr.224576.117  0.327
2017 Cox DBT, Gootenberg JS, Abudayyeh OO, Franklin B, Kellner MJ, Joung J, Zhang F. RNA editing with CRISPR-Cas13. Science (New York, N.Y.). PMID 29070703 DOI: 10.1126/Science.Aaq0180  0.324
2017 Yang L, Briggs AW, Chew WL, Mali P, Guell M, Aach J, Goodman DB, Cox D, Kan Y, Lesha E, Soundararajan V, Zhang F, Church G. Corrigendum: Engineering and optimising deaminase fusions for genome editing. Nature Communications. 8: 16169. PMID 28991237 DOI: 10.1038/Ncomms16169  0.76
2017 Wang W, Huang S, Hou W, Liu Y, Fan Q, He A, Wen Y, Hao J, Guo X, Zhang F. Integrative analysis of GWAS, eQTLs and meQTLs data suggests that multiple gene sets are associated with bone mineral density. Bone & Joint Research. 6: 572-576. PMID 28978616 DOI: 10.1302/2046-3758.610.Bjr-2017-0113.R1  0.324
2017 Jain A, Zode G, Kasetti RB, Ran FA, Yan W, Sharma TP, Bugge K, Searby CC, Fingert JH, Zhang F, Clark AF, Sheffield VC. CRISPR-Cas9-based treatment of myocilin-associated glaucoma. Proceedings of the National Academy of Sciences of the United States of America. PMID 28973933 DOI: 10.1073/Pnas.1706193114  0.315
2017 Habib N, Avraham-Davidi I, Basu A, Burks T, Shekhar K, Hofree M, Choudhury SR, Aguet F, Gelfand E, Ardlie K, Weitz DA, Rozenblatt-Rosen O, Zhang F, Regev A. Massively parallel single-nucleus RNA-seq with DroNc-seq. Nature Methods. PMID 28846088 DOI: 10.1038/Nmeth.4407  0.303
2017 Chow RD, Guzman CD, Wang G, Schmidt F, Youngblood MW, Ye L, Errami Y, Dong MB, Martinez MA, Zhang S, Renauer P, Bilguvar K, Gunel M, Sharp PA, Zhang F, et al. AAV-mediated direct in vivo CRISPR screen identifies functional suppressors in glioblastoma. Nature Neuroscience. PMID 28805815 DOI: 10.1038/Nn.4620  0.716
2017 Joung J, Engreitz JM, Konermann S, Abudayyeh OO, Verdine VK, Aguet F, Gootenberg JS, Sanjana NE, Wright JB, Fulco CP, Tseng YY, Yoon CH, Boehm JS, Lander ES, Zhang F. Genome-scale activation screen identifies a lncRNA locus regulating a gene neighbourhood. Nature. PMID 28792927 DOI: 10.1038/Nature23451  0.362
2017 Patel SJ, Sanjana NE, Kishton RJ, Eidizadeh A, Vodnala SK, Cam M, Gartner JJ, Jia L, Steinberg SM, Yamamoto TN, Merchant AS, Mehta GU, Chichura A, Shalem O, Tran E, ... Zhang F, et al. Identification of essential genes for cancer immunotherapy. Nature. PMID 28783722 DOI: 10.1038/Nature23477  0.319
2017 Yamano T, Zetsche B, Ishitani R, Zhang F, Nishimasu H, Nureki O. Structural Basis for the Canonical and Non-canonical PAM Recognition by CRISPR-Cpf1. Molecular Cell. PMID 28781234 DOI: 10.1016/J.Molcel.2017.06.035  0.318
2017 Scott DA, Zhang F. Implications of human genetic variation in CRISPR-based therapeutic genome editing. Nature Medicine. PMID 28759051 DOI: 10.1038/Nm.4377  0.482
2017 Du Y, Wen Y, Guo X, Hao J, Wang W, He A, Fan Q, Li P, Liu L, Liang X, Zhang F. A Genome-wide Expression Association Analysis Identifies Genes and Pathways Associated with Amyotrophic Lateral Sclerosis. Cellular and Molecular Neurobiology. PMID 28639078 DOI: 10.1007/S10571-017-0512-2  0.31
2017 Nishimasu H, Yamano T, Gao L, Zhang F, Ishitani R, Nureki O. Structural Basis for the Altered PAM Recognition by Engineered CRISPR-Cpf1. Molecular Cell. PMID 28595896 DOI: 10.1016/J.Molcel.2017.04.019  0.355
2017 Gao L, Cox DBT, Yan WX, Manteiga JC, Schneider MW, Yamano T, Nishimasu H, Nureki O, Crosetto N, Zhang F. Engineered Cpf1 variants with altered PAM specificities. Nature Biotechnology. PMID 28581492 DOI: 10.1038/Nbt.3900  0.379
2017 Fan Q, Wang W, Hao J, He A, Wen Y, Guo X, Wu C, Ning Y, Wang X, Wang S, Zhang F. Integrating genome-wide association study and expression quantitative trait loci data identifies multiple genes and gene set associated with neuroticism. Progress in Neuro-Psychopharmacology & Biological Psychiatry. PMID 28552732 DOI: 10.1016/J.Pnpbp.2017.05.017  0.303
2017 Tang S, Wang X, Li W, Yang X, Li Z, Liu W, Li C, Zhu Z, Wang L, Wang J, Zhang L, Sun X, Zhi E, Wang H, Li H, ... Zhang F, et al. Biallelic Mutations in CFAP43 and CFAP44 Cause Male Infertility with Multiple Morphological Abnormalities of the Sperm Flagella. American Journal of Human Genetics. PMID 28552195 DOI: 10.1016/J.Ajhg.2017.04.012  0.304
2017 Yan WX, Mirzazadeh R, Garnerone S, Scott D, Schneider MW, Kallas T, Custodio J, Wernersson E, Li Y, Gao L, Federova Y, Zetsche B, Zhang F, Bienko M, Crosetto N. BLISS is a versatile and quantitative method for genome-wide profiling of DNA double-strand breaks. Nature Communications. 8: 15058. PMID 28497783 DOI: 10.1038/Ncomms15058  0.484
2017 Platt RJ, Zhou Y, Slaymaker IM, Shetty AS, Weisbach NR, Kim JA, Sharma J, Desai M, Sood S, Kempton HR, Crabtree GR, Feng G, Zhang F. Chd8 Mutation Leads to Autistic-like Behaviors and Impaired Striatal Circuits. Cell Reports. 19: 335-350. PMID 28402856 DOI: 10.1016/J.Celrep.2017.03.052  0.717
2017 Zhang L, Wang J, Zhang C, Li D, Carvalho CM, Ji H, Xiao J, Wu Y, Zhou W, Wang H, Jin L, Luo Y, Wu X, Lupski JR, Zhang F, et al. Efficient CNV breakpoint analysis reveals unexpected structural complexity and correlation of dosage-sensitive genes with clinical severity in genomic disorders. Human Molecular Genetics. PMID 28334874 DOI: 10.1093/Hmg/Ddx102  0.346
2017 Joung J, Konermann S, Gootenberg JS, Abudayyeh OO, Platt RJ, Brigham MD, Sanjana NE, Zhang F. Genome-scale CRISPR-Cas9 knockout and transcriptional activation screening. Nature Protocols. 12: 828-863. PMID 28333914 DOI: 10.1038/Nprot.2017.016  0.723
2017 Yamada M, Watanabe Y, Gootenberg JS, Hirano H, Ran FA, Nakane T, Ishitani R, Zhang F, Nishimasu H, Nureki O. Crystal Structure of the Minimal Cas9 from Campylobacter jejuni Reveals the Molecular Diversity in the CRISPR-Cas9 Systems. Molecular Cell. 65: 1109-1121.e3. PMID 28306506 DOI: 10.1016/J.Molcel.2017.02.007  0.326
2017 Erb MA, Scott TG, Li BE, Xie H, Paulk J, Seo HS, Souza A, Roberts JM, Dastjerdi S, Buckley DL, Sanjana NE, Shalem O, Nabet B, Zeid R, Offei-Addo NK, ... Zhang F, et al. Transcription control by the ENL YEATS domain in acute leukaemia. Nature. PMID 28241139 DOI: 10.1038/Nature21688  0.359
2017 Liu P, Yuan B, Carvalho CM, Wuster A, Walter K, Zhang L, Gambin T, Chong Z, Campbell IM, Coban Akdemir Z, Gelowani V, Writzl K, Bacino CA, Lindsay SJ, Withers M, ... Zhang F, et al. An Organismal CNV Mutator Phenotype Restricted to Early Human Development. Cell. 168: 830-842.e7. PMID 28235197 DOI: 10.1016/J.Cell.2017.01.037  0.311
2017 Zetsche B, Heidenreich M, Mohanraju P, Fedorova I, Kneppers J, DeGennaro EM, Winblad N, Choudhury SR, Abudayyeh OO, Gootenberg JS, Wu WY, Scott DA, Severinov K, van der Oost J, Zhang F. Erratum: Multiplex gene editing by CRISPR-Cpf1 using a single crRNA array. Nature Biotechnology. 35: 178. PMID 28178246 DOI: 10.1038/Nbt0217-178B  0.407
2017 Shmakov S, Smargon A, Scott D, Cox D, Pyzocha N, Yan W, Abudayyeh OO, Gootenberg JS, Makarova KS, Wolf YI, Severinov K, Zhang F, Koonin EV. Diversity and evolution of class 2 CRISPR-Cas systems. Nature Reviews. Microbiology. PMID 28111461 DOI: 10.1038/Nrmicro.2016.184  0.405
2017 Smargon AA, Cox DB, Pyzocha NK, Zheng K, Slaymaker IM, Gootenberg JS, Abudayyeh OA, Essletzbichler P, Shmakov S, Makarova KS, Koonin EV, Zhang F. Cas13b Is a Type VI-B CRISPR-Associated RNA-Guided RNase Differentially Regulated by Accessory Proteins Csx27 and Csx28. Molecular Cell. PMID 28065598 DOI: 10.1016/J.Molcel.2016.12.023  0.32
2016 Zetsche B, Heidenreich M, Mohanraju P, Fedorova I, Kneppers J, DeGennaro EM, Winblad N, Choudhury SR, Abudayyeh OO, Gootenberg JS, Wu WY, Scott DA, Severinov K, van der Oost J, Zhang F. Multiplex gene editing by CRISPR-Cpf1 using a single crRNA array. Nature Biotechnology. PMID 27918548 DOI: 10.1038/Nbt.3737  0.492
2016 Maji B, Moore CL, Zetsche B, Volz SE, Zhang F, Shoulders MD, Choudhary A. Multidimensional chemical control of CRISPR-Cas9. Nature Chemical Biology. PMID 27820801 DOI: 10.1038/Nchembio.2224  0.37
2016 Yang L, Briggs AW, Chew WL, Mali P, Guell M, Aach J, Goodman DB, Cox D, Kan Y, Lesha E, Soundararajan V, Zhang F, Church G. Engineering and optimising deaminase fusions for genome editing. Nature Communications. 7: 13330. PMID 27804970 DOI: 10.1038/Ncomms13330  0.786
2016 Sanjana NE, Wright J, Zheng K, Shalem O, Fontanillas P, Joung J, Cheng C, Regev A, Zhang F. High-resolution interrogation of functional elements in the noncoding genome. Science (New York, N.Y.). 353: 1545-1549. PMID 27708104 DOI: 10.1126/Science.Aaf7613  0.365
2016 Jennings CG, Landman R, Zhou Y, Sharma J, Hyman J, Movshon JA, Qiu Z, Roberts AC, Roe AW, Wang X, Zhou H, Wang L, Zhang F, Desimone R, Feng G. Opportunities and challenges in modeling human brain disorders in transgenic primates. Nature Neuroscience. 19: 1123-1130. PMID 27571191 DOI: 10.1038/Nn.4362  0.324
2016 Shi XW, Shi BH, Lyu AL, Zhang F, Zhou TT, Guo X. Exploring Genome-wide DNA Methylation Profiles Altered in Kashin-Beck Disease Using Infinium Human Methylation 450 Bead Chips. Biomedical and Environmental Sciences : Bes. 29: 539-43. PMID 27554126 DOI: 10.3967/Bes2016.072  0.301
2016 Habib N, Li Y, Heidenreich M, Swiech L, Avraham-Davidi I, Trombetta JJ, Hession C, Zhang F, Regev A. Div-Seq: Single-nucleus RNA-Seq reveals dynamics of rare adult newborn neurons. Science (New York, N.Y.). PMID 27471252 DOI: 10.1126/Science.Aad7038  0.301
2016 Dong X, Wang X, Zhang F, Tian W. Genome-wide identification of regulatory sequences undergoing accelerated evolution in the human genome. Molecular Biology and Evolution. PMID 27401230 DOI: 10.1093/Molbev/Msw128  0.438
2016 Guan J, Wang D, Cao W, Zhao Y, Du R, Yuan H, Liu Q, Lan L, Zong L, Yang J, Yin Z, Han B, Zhang F, Wang Q. SIX2 haploinsufficiency causes conductive hearing loss with ptosis in humans. Journal of Human Genetics. PMID 27383657 DOI: 10.1038/Jhg.2016.86  0.306
2016 Duan Y, Ma G, Huang X, D'Amore PA, Zhang F, Lei H. The CRISPR/Cas9-created MDM2 T309G enhances vitreous-induced expression of MDM2 and proliferation and survival of cells. The Journal of Biological Chemistry. PMID 27246850 DOI: 10.1074/Jbc.M116.729467  0.315
2016 Zhu XB, Lu JQ, Zhi EL, Zhu Y, Zou SS, Zhu ZJ, Zhang F, Li Z. Association of a TDRD1 variant with spermatogenic failure susceptibility in the Han Chinese. Journal of Assisted Reproduction and Genetics. PMID 27233649 DOI: 10.1007/S10815-016-0738-9  0.323
2016 Wang S, Su JH, Zhang F, Zhuang X. An RNA-aptamer-based two-color CRISPR labeling system. Scientific Reports. 6: 26857. PMID 27229896 DOI: 10.1038/Srep26857  0.307
2016 Stoddard TJ, Clasen BM, Baltes NJ, Demorest ZL, Voytas DF, Zhang F, Luo S. Targeted Mutagenesis in Plant Cells through Transformation of Sequence-Specific Nuclease mRNA. Plos One. 11: e0154634. PMID 27176769 DOI: 10.1371/Journal.Pone.0154634  0.331
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2007 Hwang RY, Zhong L, Xu Y, Johnson T, Zhang F, Deisseroth K, Tracey WD. Nociceptive neurons protect Drosophila larvae from parasitoid wasps. Current Biology : Cb. 17: 2105-16. PMID 18060782 DOI: 10.1016/J.Cub.2007.11.029  0.478
2007 Adamantidis AR, Zhang F, Aravanis AM, Deisseroth K, de Lecea L. Neural substrates of awakening probed with optogenetic control of hypocretin neurons. Nature. 450: 420-4. PMID 17943086 DOI: 10.1038/Nature06310  0.492
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2007 Yang G, Zhang F, Hancock CN, Wessler SR. Transposition of the rice miniature inverted repeat transposable element mPing in Arabidopsis thaliana. Proceedings of the National Academy of Sciences of the United States of America. 104: 10962-7. PMID 17578919 DOI: 10.1073/Pnas.0702080104  0.324
2007 Wang H, Peca J, Matsuzaki M, Matsuzaki K, Noguchi J, Qiu L, Wang D, Zhang F, Boyden E, Deisseroth K, Kasai H, Hall WC, Feng G, Augustine GJ. High-speed mapping of synaptic connectivity using photostimulation in Channelrhodopsin-2 transgenic mice. Proceedings of the National Academy of Sciences of the United States of America. 104: 8143-8. PMID 17483470 DOI: 10.1073/Pnas.0700384104  0.525
2007 Zhang F, Wang LP, Brauner M, Liewald JF, Kay K, Watzke N, Wood PG, Bamberg E, Nagel G, Gottschalk A, Deisseroth K. Multimodal fast optical interrogation of neural circuitry. Nature. 446: 633-9. PMID 17410168 DOI: 10.1038/Nature05744  0.549
2007 Hwang RY, Zhong L, Xu Y, Johnson T, Zhang F, Deisseroth K, Tracey WD. Nociceptive Neurons Protect Drosophila Larvae from Parasitoid Wasps (DOI:10.1016/j.cub.2007.11.029) Current Biology. 17: 2183. DOI: 10.1016/J.Cub.2007.12.018  0.471
2006 Zhang J, Zhang F, Peterson T. Transposition of reversed Ac element ends generates novel chimeric genes in maize. Plos Genetics. 2: e164. PMID 17029561 DOI: 10.1371/Journal.Pgen.0020164  0.301
2006 Zhang F, Wang LP, Boyden ES, Deisseroth K. Channelrhodopsin-2 and optical control of excitable cells. Nature Methods. 3: 785-92. PMID 16990810 DOI: 10.1038/Nmeth936  0.538
2006 Zhang F, Peterson T. Gene conversion between direct noncoding repeats promotes genetic and phenotypic diversity at a regulatory locus of Zea mays (L.). Genetics. 174: 753-62. PMID 16816430 DOI: 10.1534/Genetics.105.053942  0.333
2005 Boyden ES, Zhang F, Bamberg E, Nagel G, Deisseroth K. Millisecond-timescale, genetically targeted optical control of neural activity. Nature Neuroscience. 8: 1263-8. PMID 16116447 DOI: 10.1038/Nn1525  0.554
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