Wen-Qiang Chen, Ph.D. - Related publications

Affiliations: 
2008-2011 New Drug Evaluations Beijing Institute of Pharmacology & Toxicology 
 2011-2016 Physiology The University of Hong Kong, San Francisco, Hong Kong Island, Hong Kong 
 2017-2019 Program in Cellular Molecular Medicine Harvard Medical School - Boston Children's Hospital 
Area:
Neurobiology, drug addiction, depression
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50 most relevant papers in past 60 days:
Year Citation  Score
2021 Liu XW, Ma B, Zi Y, Xiang LB, Han TY. Effects of rutin on osteoblast MC3T3-E1 differentiation, ALP activity and Runx2 protein expression. European Journal of Histochemistry : Ejh. 65. PMID 33478200 DOI: 10.4081/ejh.2021.3195   
2021 Lu LM, Fu Y, Li QY, He XW, Tang J, Li XW. [Chrysin inhibited epithelial-mesenchymal transition of type Ⅱ alveolar epithelial cell by regulating NF-κB/Twist 1 signaling pathway]. Zhongguo Zhong Yao Za Zhi = Zhongguo Zhongyao Zazhi = China Journal of Chinese Materia Medica. 46: 146-154. PMID 33645064 DOI: 10.19540/j.cnki.cjcmm.20200810.402   
2021 Park E, Kim KT, Choi M, Lee Y, Paik HD. In Vivo Evaluation of Immune-Enhancing Activity of Red Gamju Fermented by Probiotic KU15154 in Mice. Foods (Basel, Switzerland). 10. PMID 33530528 DOI: 10.3390/foods10020253   
2021 Li N, Jiang S, Fu R, Lv J, Yao J, Mai J, Hua X, Chen H, Liu J, Lu M. Cleavage and polyadenylation-specific factor 3 induces cell cycle arrest via PI3K/Akt/GSK-3β signaling pathways and predicts a negative prognosis in hepatocellular carcinoma. Biomarkers in Medicine. PMID 33666519 DOI: 10.2217/bmm-2021-0039   
2021 Heidarzadeh M, Avcı ÇB, Saberianpour S, Ahmadi M, Hassanpour M, Bagheri HS, Rezaie J, Talebi M, Roodbari F, Sokullu E, Darabi M, Rahbarghazi R. Activation of toll-like receptor signaling in endothelial progenitor cells dictates angiogenic potential: from hypothesis to actual state. Cell and Tissue Research. PMID 33459880 DOI: 10.1007/s00441-020-03405-4   
2021 Alazzouni AS, Mahmoud AA, Omran MM, Essawy EA, Abdalla MS, Abdelfattah MS. Inhibitory and ameliorative effect of heliomycin derived from actinomycete on induced hepatocellular carcinoma in rats. Naunyn-Schmiedeberg's Archives of Pharmacology. PMID 33416934 DOI: 10.1007/s00210-020-02043-5   
2021 Wu CJ, Fu FD, Qin F, Ma M, Li T, Wei SZ, Yu BT, Yang XZ, Yuan JH. Vacuum therapy ameliorates erectile dysfunction in bilateral cavernous nerve crush rats by inhibiting apoptosis and activating autophagy. Asian Journal of Andrology. PMID 33473012 DOI: 10.4103/aja.aja_79_20   
2021 Wu CJ, Fu FD, Qin F, Ma M, Li T, Wei SZ, Yu BT, Yang XZ, Yuan JH. Vacuum therapy ameliorates erectile dysfunction in bilateral cavernous nerve crush rats by inhibiting apoptosis and activating autophagy. Asian Journal of Andrology. PMID 33473012 DOI: 10.4103/aja.aja_79_20   
2021 Ghaffari K, Ahmadi R, Saberi B, Moulavi P. Anti-proliferative effects of Ziziphus spina-christi and Phlomis russeliana leaf extracts on HEK293 and MCF-7 Cell Lines and Evaluation of Bax and Bcl-2 Genes Expression Level in MCF-7 Cells. Asian Pacific Journal of Cancer Prevention : Apjcp. 22: 81-87. PMID 33576216 DOI: 10.31557/APJCP.2021.22.S1.81   
2021 Chen SM, Jahejo AR, Nabi F, Ahmed S, Zhao JF, Yu J, Zhang CL, Ning GB, Zhang D, Raza SHA, Tian WX. Janus kinase/signal transducer and activator of transcription signaling pathway-related genes STAT3, SOCS3 and their role in thiram induced tibial dyschondroplasia chickens. Research in Veterinary Science. 136: 25-31. PMID 33578291 DOI: 10.1016/j.rvsc.2021.01.024   
2021 Chen X, Zhang W, Zhu H, Lin F. Development and Validation of a 5-Gene Autophagy-Based Prognostic Index in Endometrial Carcinoma. Medical Science Monitor : International Medical Journal of Experimental and Clinical Research. 27: e928949. PMID 33577492 DOI: 10.12659/MSM.928949   
2021 Que DH, Chen WH, Jiang FP, Pan F, Yang K. [Mechanism of Danggui Sini Decoction in treatment of primary dysmenorrhea based on network pharmacology and molecular docking]. Zhongguo Zhong Yao Za Zhi = Zhongguo Zhongyao Zazhi = China Journal of Chinese Materia Medica. 46: 855-864. PMID 33645090 DOI: 10.19540/j.cnki.cjcmm.20201104.401   
2021 Huang CC, Chou CH, Yang YS, Ho HN, Shun CT, Wen WF, Chen SU, Chen MJ. Metformin: a novel promising option for fertility preservation during cyclophosphamide-based chemotherapy. Molecular Human Reproduction. 27. PMID 33543290 DOI: 10.1093/molehr/gaaa084   
2021 Lopes F, Tholeti P, Adiga SK, Anderson RA, Mitchell RT, Spears N. Chemotherapy induced damage to spermatogonial stem cells in prepubertal mouse in vitro impairs long-term spermatogenesis. Toxicology Reports. 8: 114-123. PMID 33425685 DOI: 10.1016/j.toxrep.2020.12.023   
2021 Lim DR, Kang DH, Kuk JC, Kim TH, Shin EJ, Ahn TS, Kim HJ, Jeong DJ, Baek MJ, Kim NK. Prognostic impact of GPR56 in patients with colorectal cancer. Neoplasma. PMID 33618521 DOI: 10.4149/neo_2021_201209N1333   
2021 Zhao L, Lian T, Li J, Wei S, Li H, Li C, Wang H. NCR3LG1(B7-H6) is a potential prognostic factor for bladder cancer patients. Biomarkers : Biochemical Indicators of Exposure, Response, and Susceptibility to Chemicals. 1-20. PMID 33523715 DOI: 10.1080/1354750X.2021.1883110   
2021 Byun JM, Cho HJ, Park HY, Lee DS, Choi IH, Kim YN, Jeong CH, Kim DH, Hwa Im D, Min BJ, Lee KB, Sung MS, Jeong DH. The clinical significance of HERV-H LTR -associating 2 expression in cervical adenocarcinoma. Medicine. 100: e23691. PMID 33429737 DOI: 10.1097/MD.0000000000023691   
2021 Park MS, Lee YE, Kim HR, Shin JH, Cho HW, Lee JH, Shin MG. Phospholipase C Beta 2 Protein Overexpression Is a Favorable Prognostic Indicator in Newly Diagnosed Normal Karyotype Acute Myeloid Leukemia. Annals of Laboratory Medicine. 41: 409-413. PMID 33536360 DOI: 10.3343/alm.2021.41.4.409   
2021 Wang L, Yi JL, Chen HY, Wang PL, Shen YL. Level of Foxp3, DNMTs, methylation of Foxp3 promoter region, and CD4 + CD25 + CD127low regulatory T cells in vulvar lichen sclerosus. The Kaohsiung Journal of Medical Sciences. PMID 33438816 DOI: 10.1002/kjm2.12356   
2021 Kennedy E, Coulter EM, Halliwell E, Profitos-Peleja N, Walsby E, Clark B, Phillips EH, Burley TA, Mitchell S, Devereux S, Fegan C, Jones CI, Johnston R, Chevassut TJ, Schulz R, et al. TLR9 expression in Chronic Lymphocytic Leukemia identifies a pro-migratory subpopulation and novel therapeutic target. Blood. PMID 33512408 DOI: 10.1182/blood.2020005964   
2021 Bai Y, Gu CY, Pan R, Abid M, Zang HY, Yang X, Tan G, Chen Y. Activity of A Novel Succinate Dehydrogenase Inhibitor Fungicide Pydiflumetofen against Fusarium fujikuroi causing Rice Bakanae Disease. Plant Disease. PMID 33560887 DOI: 10.1094/PDIS-10-20-2274-RE   
2021 Zhu YT, Zhang YF, Jiang JF, Yang Y, Guo LX, Bao JJ, Zhong DF. Effects of rifampicin on the pharmacokinetics of alflutinib, a selective third-generation EGFR kinase inhibitor, and its metabolite AST5902 in healthy volunteers. Investigational New Drugs. PMID 33506323 DOI: 10.1007/s10637-021-01071-z   
2021 Cai Z, Wei J, Chen Z, Wang H. High expression predicts poor survival in non-M3 acute myeloid leukemia. Experimental Biology and Medicine (Maywood, N.J.). 1535370220988246. PMID 33541130 DOI: 10.1177/1535370220988246   
2021 Gu J, Zhang S, He X, Chen S, Wang Y. High expression of PIG11 correlates with poor prognosis in gastric cancer. Experimental and Therapeutic Medicine. 21: 249. PMID 33603857 DOI: 10.3892/etm.2021.9680   
2021 Yang X, Li B, Guan Y, Jiang HM. Expressions and related mechanisms of miR-212 and KLF4 in rats with acute kidney injury. Molecular and Cellular Biochemistry. PMID 33428060 DOI: 10.1007/s11010-020-04016-x   
2021 Han K, Du SS, Wang H, Qiao JJ, Zhang X, Wang P, Shen FH. [Differential expression of PRDX4 in alveolar macrophages of patients with silicosis]. Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi = Zhonghua Laodong Weisheng Zhiyebing Zazhi = Chinese Journal of Industrial Hygiene and Occupational Diseases. 39: 17-19. PMID 33535333 DOI: 10.3760/cma.j.cn121094-20190417-00155   
2021 Xagoraris I, Vassilakopoulos TP, Drakos E, Angelopoulou MK, Panitsas F, Herold N, Medeiros LJ, Giakoumis X, Pangalis GA, Rassidakis GZ. Expression of the novel tumour suppressor sterile alpha motif and HD domain-containing protein 1 is an independent adverse prognostic factor in classical Hodgkin lymphoma. British Journal of Haematology. PMID 33528031 DOI: 10.1111/bjh.17352   
2021 Xagoraris I, Vassilakopoulos TP, Drakos E, Angelopoulou MK, Panitsas F, Herold N, Medeiros LJ, Giakoumis X, Pangalis GA, Rassidakis GZ. Expression of the novel tumour suppressor sterile alpha motif and HD domain-containing protein 1 is an independent adverse prognostic factor in classical Hodgkin lymphoma. British Journal of Haematology. PMID 33528031 DOI: 10.1111/bjh.17352   
2021 Molnár S, Vida B, Beke L, Méhes G, Póka R. The Prognostic Relevance of Poly (ADP-Ribose) Polymerase Expression in Ovarian Cancer Tissue of Wild Type and BRCA-Mutation Carrier Patients. Diagnostics (Basel, Switzerland). 11. PMID 33478135 DOI: 10.3390/diagnostics11010144   
2021 Mo M, Li Y, Hu X. Serum CXCL5 level is associated with tumor progression in penile cancer. Bioscience Reports. PMID 33458757 DOI: 10.1042/BSR20202133   
2021 Yu B, Zheng X, Sun Z, Cao P, Zhang J, Wang W. Can Be Used as a Biomarker for Diagnosis of Renal Cell Carcinoma and Prediction of Patient Survival. Frontiers in Genetics. 12: 599952. PMID 33659024 DOI: 10.3389/fgene.2021.599952   
2021 Kang ZP, Wang LX, Liu J, Ouyang H, Xie S, Tan Y. Expression of CEACAM1 and CD105 in Renal Cell Carcinoma and Its Correlation with Microvessel Density. Critical Reviews in Eukaryotic Gene Expression. 31: 1-9. PMID 33639050 DOI: 10.1615/CritRevEukaryotGeneExpr.2020037168   
2021 Li GZ, Shen D, Li GH, Wei M, Zheng LJ, Liu ZL, Sun RQ, Zhou SJ, Zhang ZL, Gao YC. Decreased expression of serum semaphorin 3B is associated with poor prognosis of patients with hepatocellular carcinoma. Experimental and Therapeutic Medicine. 21: 236. PMID 33603844 DOI: 10.3892/etm.2021.9667   
2021 Ahluwalia P, Ahluwalia M, Mondal AK, Sahajpal N, Kota V, Rojiani MV, Rojiani AM, Kolhe R. Immunogenomic Gene Signature of Cell-Death Associated Genes with Prognostic Implications in Lung Cancer. Cancers. 13. PMID 33466402 DOI: 10.3390/cancers13010155   
2021 Pillay Y, Ghazi T, Raghubeer S, Nagiah S, Chuturgoon AA. Patulin activates the NRF2 pathway by modulation of miR-144 expression in HEK293 cells. Mycotoxin Research. PMID 33403569 DOI: 10.1007/s12550-020-00418-4   
2021 Yang W, Li L, Zhang K, Ma K, Xie H, Gong Y, Zhou J, Gong K. ACE2 Correlated With Immune Infiltration Serves As A Novel Prognostic Biomarker In Clear Cell Renal Cell Carcinoma: Implication For COVID-19. International Journal of Biological Sciences. 17: 20-31. PMID 33390830 DOI: 10.7150/ijbs.51969   
2021 Leu M, Kitz J, Pilavakis Y, Hakroush S, Wolff HA, Canis M, Rieken S, Schirmer MA. Monocarboxylate transporter-1 (MCT1) protein expression in head and neck cancer affects clinical outcome. Scientific Reports. 11: 4578. PMID 33633176 DOI: 10.1038/s41598-021-84019-w   
2021 Song Y, Cui Y, Hao L, Zhu J, Yi J, Kang Q, Huang J, Lu J. Wound-healing activity of glycoproteins from white jade snail (Achatina fulica) on experimentally burned mice. International Journal of Biological Macromolecules. PMID 33539960 DOI: 10.1016/j.ijbiomac.2021.01.193   
2021 Lv Z, Yue Z, Shao Y, Li C, Zhao X, Guo M. mTORC2/Rictor is essential for coelomocyte endocytosis in Apostichopus japonicus. Developmental and Comparative Immunology. 104000. PMID 33444645 DOI: 10.1016/j.dci.2021.104000   
2021 Meng L, Li Y, Xue C, Ding C, Wang X, Fu R, Li Y, Li X, Dong Z. Compound danshen dripping pills affect the pharmacokinetics of azisartan by regulating the expression of cytochrome P450 2B1, 2C6, and 2C11 in rats. Journal of Pharmaceutical and Biomedical Analysis. 195: 113887. PMID 33418444 DOI: 10.1016/j.jpba.2020.113887   
2021 Dai Y, Li TH, He X, Yan SB, Gao Y, Chen Y. The Effect and Mechanism of Asymmetric Dimethylarginine Regulating Trophoblastic Autophagy on Fetal Growth Restriction. Reproductive Sciences (Thousand Oaks, Calif.). PMID 33428125 DOI: 10.1007/s43032-020-00442-w   
2021 Wen Y, Chun Y, Lian ZQ, Yong ZW, Lan YM, Huan L, Xi CY, Juan LS, Qing ZW, Jia C, Ji ZH. circRNA‑0006896‑miR1264‑DNMT1 axis plays an important role in carotid plaque destabilization by regulating the behavior of endothelial cells in atherosclerosis. Molecular Medicine Reports. 23. PMID 33649864 DOI: 10.3892/mmr.2021.11950   
2021 Zhang X, Zhang X, Li X, Bao H, Li G, Li N, Li H, Dou J. Acts as a Promising Novel Biomarker for the Prognosis of Patients with Hepatocellular Carcinoma. Cancer Biotherapy & Radiopharmaceuticals. PMID 33601927 DOI: 10.1089/cbr.2020.4226   
2021 Jia H, Wang X, Sun Z. Screening and validation of plasma long non-coding RNAs as biomarkers for the early diagnosis and staging of oral squamous cell carcinoma. Oncology Letters. 21: 172. PMID 33552289 DOI: 10.3892/ol.2021.12433   
2021 Xie J, Peng Y, Chen X, Li Q, Jian B, Wen Z, Liu S. LACTB mRNA expression is increased in pancreatic adenocarcinoma and high expression indicates a poor prognosis. Plos One. 16: e0245908. PMID 33507917 DOI: 10.1371/journal.pone.0245908   
2021 Zhong B, Shen J, Zhang C, Zhou G, Yu Y, Qin E, Tang J, Wu D, Liang X. Plasma Heat Shock Protein 90 Alpha: A Valuable Predictor of Early Chemotherapy Effectiveness in Advanced Non-Small-Cell Lung Cancer. Medical Science Monitor : International Medical Journal of Experimental and Clinical Research. 27: e924778. PMID 33419959 DOI: 10.12659/MSM.924778   
2021 Yang HH, Jhang JF, Hsu YH, Jiang YH, Zhai WJ, Kuo HC. Smaller bladder capacity and stronger bladder contractility in patients with ketamine cystitis are associated with elevated TRPV1 and TRPV4. Scientific Reports. 11: 5200. PMID 33664402 DOI: 10.1038/s41598-021-84734-4   
2021 Wu ZH, Tang Y, Zhou Y. Alternative splicing events implicated in carcinogenesis and prognosis of thyroid gland cancer. Scientific Reports. 11: 4841. PMID 33649373 DOI: 10.1038/s41598-021-84403-6   
2021 Coelho-Silva JL, Silveira DRA, Pereira-Martins DA, Rojas CAO, Lucena-Araujo AR, Rego EM, Machado-Neto JA, Bendit I, Rocha V, Traina F. Molecular-Based Score inspired on metabolic signature improves prognostic stratification for myelodysplastic syndrome. Scientific Reports. 11: 1675. PMID 33462268 DOI: 10.1038/s41598-020-80918-6   
2021 Ding Z, Bai Z, Zhang M, Sun B, He Y. cIAP2 expression and clinical significance in pigmented villonodular synovitis. Journal of Molecular Histology. PMID 33599891 DOI: 10.1007/s10735-021-09961-5