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Lei Zhou - Publications

Affiliations: 
Virginia Commonwealth University, Richmond, VA, United States 
Area:
CNG channels, HCN channels
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36 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Wei F, Wang Q, Han J, Goswamee P, Gupta A, McQuiston AR, Liu Q, Zhou L. Photodynamic modification of native HCN channels expressed in thalamocortical neurons. Acs Chemical Neuroscience. PMID 32078767 DOI: 10.1021/Acschemneuro.9B00475  0.343
2019 Li H, Zhu H, Sarbeng EB, Liu Q, Tian X, Yang Y, Lyons C, Zhou L, Liu Q. An unexpected second binding site for polypeptide substrates is essential for Hsp70 chaperone activity. The Journal of Biological Chemistry. PMID 31806707 DOI: 10.1074/Jbc.Ra119.009686  0.302
2019 Wei F, Wang Q, Gupta A, Liu Q, Zhou L. Photodynamic Modification of Native HCN Channels in Thalamocortical Neurons Biophysical Journal. 116. DOI: 10.1016/J.Bpj.2018.11.1354  0.338
2018 Idikuda V, Gao W, Su Z, Liu Q, Zhou L. cAMP binds to closed, inactivated, and open sea urchin HCN channels in a state-dependent manner. The Journal of General Physiology. PMID 30541772 DOI: 10.1085/Jgp.201812019  0.45
2018 Idikuda V, Gao W, Grant K, Su Z, Liu Q, Zhou L. Singlet oxygen modification abolishes voltage-dependent inactivation of the sea urchin spHCN channel. The Journal of General Physiology. PMID 30042141 DOI: 10.1085/Jgp.201711961  0.346
2017 Yang J, Zong Y, Su J, Li H, Zhu H, Columbus L, Zhou L, Liu Q. Conformation transitions of the polypeptide-binding pocket support an active substrate release from Hsp70s. Nature Communications. 8: 1201. PMID 29084938 DOI: 10.1038/S41467-017-01310-Z  0.319
2016 Liu C, Xie C, Grant K, Su Z, Gao W, Liu Q, Zhou L. Patch-clamp fluorometry-based channel counting to determine HCN channel conductance. The Journal of General Physiology. 148: 65-76. PMID 27353446 DOI: 10.1085/Jgp.201511559  0.423
2016 Grant KL, Liu C, Zhou L. Patch-Clamp Fluorometry based Determination of Relative Ion Permeability for HCN Channels Biophysical Journal. 110. DOI: 10.1016/J.Bpj.2015.11.614  0.37
2015 Yang J, Nune M, Zong Y, Zhou L, Liu Q. Close and Allosteric Opening of the Polypeptide-Binding Site in a Human Hsp70 Chaperone BiP. Structure (London, England : 1993). 23: 2191-2203. PMID 26655470 DOI: 10.1016/J.Str.2015.10.012  0.326
2015 Idikuda VK, Gao W, Su Z(, Zhou L. Photodynamic Modification of Sea Urchin spHCN Channel Biophysical Journal. 108. DOI: 10.1016/J.Bpj.2014.11.1582  0.405
2014 Gao W, Su Z, Liu Q, Zhou L. State-dependent and site-directed photodynamic transformation of HCN2 channel by singlet oxygen. The Journal of General Physiology. 143: 633-44. PMID 24733837 DOI: 10.1085/Jgp.201311112  0.388
2014 Gao W, Su Z, Liu Q, Zhou L. Two Separate Sites Compete for Singlet Oxygen in the Photodynamic Modification of HCN Channels Biophysical Journal. 106. DOI: 10.1016/J.Bpj.2013.11.4170  0.375
2014 Liu Q, Qi R, Sarbeng E, Liu Q, Le K, Xu X, Xu H, Yang J, Wong J, Vorvis C, Hendrickson W, Zhou L. Allosteric Opening of the Polypeptide-Binding Site When an Hsp70 Binds ATP Biophysical Journal. 106: 2-7. DOI: 10.1016/J.Bpj.2013.11.1446  0.32
2013 Qi R, Sarbeng EB, Liu Q, Le KQ, Xu X, Xu H, Yang J, Wong JL, Vorvis C, Hendrickson WA, Zhou L, Liu Q. Allosteric opening of the polypeptide-binding site when an Hsp70 binds ATP. Nature Structural & Molecular Biology. 20: 900-7. PMID 23708608 DOI: 10.1038/Nsmb.2583  0.336
2013 Zhou L, Logothetis DE. The where and how of PIP regulation of cone photoreceptor CNG channels. The Journal of General Physiology. 141: 403-7. PMID 23530135 DOI: 10.1085/Jgp.201310981  0.38
2013 Su Z, Gao W, Xu H, Xie C, Liu Q, Zhou L. Counting of Ion Channels on a Membrane Patch Aided by Patch-Clamp Fluorometry Biophysical Journal. 104. DOI: 10.1016/J.Bpj.2012.11.1562  0.406
2013 Gao W, Su Z, Liu Q, Zhou L. Inactivated spHCN Channel has a Decreased Binding Affinity for Camp Biophysical Journal. 104. DOI: 10.1016/J.Bpj.2012.11.1561  0.438
2012 Xu X, Marni F, Wu S, Su Z, Musayev F, Shrestha S, Xie C, Gao W, Liu Q, Zhou L. Local and global interpretations of a disease-causing mutation near the ligand entry path in hyperpolarization-activated cAMP-gated channel. Structure (London, England : 1993). 20: 2116-23. PMID 23103389 DOI: 10.1016/J.Str.2012.09.017  0.444
2012 Marni F, Wu S, Shah GM, Xu XP, Hackett AR, Xie C, Shrestha S, Liu L, Liu Q, Zhou L. Normal-mode-analysis-guided investigation of crucial intersubunit contacts in the cAMP-dependent gating in HCN channels Biophysical Journal. 103: 19-28. PMID 22828328 DOI: 10.1016/J.Bpj.2012.05.030  0.44
2012 Wu S, Gao W, Xie C, Xu X, Vorvis C, Marni F, Hackett AR, Liu Q, Zhou L. Inner activation gate in S6 contributes to the state-dependent binding of cAMP in full-length HCN2 channel. The Journal of General Physiology. 140: 29-39. PMID 22689828 DOI: 10.1085/Jgp.201110749  0.448
2012 Zhou L. Ion channels: Cooperativity in twin gatings Nature Chemical Biology. 8: 136-137. PMID 22257850 DOI: 10.1038/Nchembio.776  0.424
2011 Wu S, Vysotskaya ZV, Xu X, Xie C, Liu Q, Zhou L. State-dependent cAMP binding to functioning HCN channels studied by patch-clamp fluorometry. Biophysical Journal. 100: 1226-32. PMID 21354395 DOI: 10.1016/J.Bpj.2011.01.034  0.436
2011 Xu X, Vysotskaya ZV, Liu Q, Zhou L. Structural and Biochemical Study of CAMP-Dependent Regulation of Human HCN4 Channel Biophysical Journal. 100: 1-4. DOI: 10.1016/J.Bpj.2010.12.778  0.443
2010 Xu X, Vysotskaya ZV, Liu Q, Zhou L. Structural basis for the cAMP-dependent gating in the human HCN4 channel. The Journal of Biological Chemistry. 285: 37082-91. PMID 20829353 DOI: 10.1074/Jbc.M110.152033  0.433
2009 Bell DC, Turbendian HK, Valley MT, Zhou L, Riley JH, Siegelbaum SA, Tibbs GR. Probing S4 and S5 segment proximity in mammalian hyperpolarization-activated HCN channels by disulfide bridging and Cd2+ coordination. PflüGers Archiv : European Journal of Physiology. 458: 259-72. PMID 19034494 DOI: 10.1007/S00424-008-0613-3  0.6
2008 Zhou L, Siegelbaum SA. Pathway and endpoint free energy calculations for cyclic nucleotide binding to HCN channels. Biophysical Journal. 94: L90-2. PMID 18408037 DOI: 10.1529/Biophysj.108.130872  0.604
2008 Zhou L, Siegelbaum SA. Effects of surface water on protein dynamics studied by a novel coarse-grained normal mode approach. Biophysical Journal. 94: 3461-74. PMID 18212016 DOI: 10.1529/Biophysj.107.115956  0.499
2007 Zhou L, Siegelbaum SA. Gating of HCN channels by cyclic nucleotides: residue contacts that underlie ligand binding, selectivity, and efficacy. Structure (London, England : 1993). 15: 655-70. PMID 17562313 DOI: 10.1016/J.Str.2007.04.012  0.605
2007 Chen S, Wang J, Zhou L, George MS, Siegelbaum SA. Voltage sensor movement and cAMP binding allosterically regulate an inherently voltage-independent closed-open transition in HCN channels. The Journal of General Physiology. 129: 175-88. PMID 17261842 DOI: 10.1085/Jgp.200609585  0.678
2004 Zhou L, Olivier NB, Yao H, Young EC, Siegelbaum SA. A conserved tripeptide in CNG and HCN channels regulates ligand gating by controlling C-terminal oligomerization. Neuron. 44: 823-34. PMID 15572113 DOI: 10.1016/J.Neuron.2004.11.012  0.662
2002 McCormack K, Connor JX, Zhou L, Ho LL, Ganetzky B, Chiu SY, Messing A. Genetic analysis of the mammalian K+ channel beta subunit Kvbeta 2 (Kcnab2). The Journal of Biological Chemistry. 277: 13219-28. PMID 11825900 DOI: 10.1074/Jbc.M111465200  0.56
2000 Wrabetz L, Feltri ML, Quattrini A, Imperiale D, Previtali S, D'Antonio M, Martini R, Yin X, Trapp BD, Zhou L, Chiu SY, Messing A. P(0) glycoprotein overexpression causes congenital hypomyelination of peripheral nerves. The Journal of Cell Biology. 148: 1021-34. PMID 10704451 DOI: 10.1083/Jcb.148.5.1021  0.498
1999 Chiu SY, Zhou L, Zhang CL, Messing A. Analysis of potassium channel functions in mammalian axons by gene knockouts. Journal of Neurocytology. 28: 349-64. PMID 10739576 DOI: 10.1023/A:1007013731231  0.561
1999 Arroyo EJ, Xu YT, Zhou L, Messing A, Peles E, Chiu SY, Scherer SS. Myelinating Schwann cells determine the internodal localization of Kv1.1, Kv1.2, Kvbeta2, and Caspr. Journal of Neurocytology. 28: 333-47. PMID 10739575 DOI: 10.1023/A:1007009613484  0.538
1999 Zhou L, Messing A, Chiu SY. Determinants of excitability at transition zones in Kv1.1-deficient myelinated nerves. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 5768-81. PMID 10407018 DOI: 10.1523/Jneurosci.19-14-05768.1999  0.564
1998 Zhou L, Zhang CL, Messing A, Chiu SY. Temperature-sensitive neuromuscular transmission in Kv1.1 null mice: role of potassium channels under the myelin sheath in young nerves. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 7200-15. PMID 9736643 DOI: 10.1523/Jneurosci.18-18-07200.1998  0.58
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