Servio H. Ramirez, Ph.D - Publications

Pathology and Laboratory Medicine Temple University School of Medicine, Philadelphia, PA, United States 
blood-brain barrier, neuroinflammation

61 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Cannella LA, Andrews A, Tran F, Razmpour R, McGary HM, Collie C, Tsegaye T, Maynard M, Kaufman MJ, Rawls SM, Ramirez SH. Experimental Traumatic Brain Injury during Adolescence Enhances Cocaine Rewarding Efficacy and Dysregulates Dopamine and Neuroimmune Systems in Brain Reward Substrates. Journal of Neurotrauma. PMID 31347447 DOI: 10.1089/neu.2019.6472  0.92
2019 Vagnozzi AN, Li JG, Chiu J, Razmpour R, Warfield R, Ramirez SH, Praticò D. VPS35 regulates tau phosphorylation and neuropathology in tauopathy. Molecular Psychiatry. PMID 31289348 DOI: 10.1038/s41380-019-0453-x  0.92
2019 Lutton EM, Farney SK, Andrews AM, Shuvaev VV, Chuang GY, Muzykantov VR, Ramirez SH. Endothelial Targeted Strategies to Combat Oxidative Stress: Improving Outcomes in Traumatic Brain Injury. Frontiers in Neurology. 10: 582. PMID 31275220 DOI: 10.3389/fneur.2019.00582  0.92
2019 Kotredes KP, Razmpour R, Lutton E, Alfonso-Prieto M, Ramirez SH, Gamero AM. Characterization of cancer-associated IDH2 mutations that differ in tumorigenicity, chemosensitivity and 2-hydroxyglutarate production. Oncotarget. 10: 2675-2692. PMID 31105869 DOI: 10.18632/oncotarget.26848  0.92
2019 Tomar D, Jaña F, Dong Z, Quinn WJ, Jadiya P, Breves SL, Daw CC, Srikantan S, Shanmughapriya S, Nemani N, Carvalho E, Tripathi A, Worth AM, Zhang X, Razmpour R, ... ... Ramirez SH, et al. Blockade of MCU-Mediated Ca Uptake Perturbs Lipid Metabolism via PP4-Dependent AMPK Dephosphorylation. Cell Reports. 26: 3709-3725.e7. PMID 30917323 DOI: 10.1016/j.celrep.2019.02.107  0.92
2019 Cannella LA, McGary H, Ramirez SH. Brain interrupted: Early life traumatic brain injury and addiction vulnerability. Experimental Neurology. PMID 30862466 DOI: 10.1016/j.expneurol.2019.03.003  0.92
2018 Ramirez SH, Andrews AM, Paul D, Pachter JS. Extracellular vesicles: mediators and biomarkers of pathology along CNS barriers. Fluids and Barriers of the Cns. 15: 19. PMID 29960602 DOI: 10.1186/s12987-018-0104-7  0.92
2018 Brailoiu E, Barlow CL, Ramirez SH, Abood ME, Brailoiu GC. Effects of Platelet-Activating Factor on brain microvascular endothelial cells. Neuroscience. PMID 29522856 DOI: 10.1016/j.neuroscience.2018.02.039  0.32
2017 Merkel SF, Andrews AM, Lutton EM, Razmpour R, Cannella LA, Ramirez SH. Dexamethasone Attenuates the Enhanced Rewarding Effects of Cocaine Following Experimental Traumatic Brain Injury. Cell Transplantation. 26: 1178-1192. PMID 28933216 DOI: 10.1177/0963689717714341  0.92
2017 Lutton EM, Razmpour R, Andrews AM, Cannella LA, Son YJ, Shuvaev VV, Muzykantov VR, Ramirez SH. Acute administration of catalase targeted to ICAM-1 attenuates neuropathology in experimental traumatic brain injury. Scientific Reports. 7: 3846. PMID 28630485 DOI: 10.1038/s41598-017-03309-4  0.92
2017 Sagar D, Singh NP, Ginwala R, Huang X, Philip R, Nagarkatti M, Nagarkatti P, Neumann K, Ruland J, Andrews AM, Ramirez SH, Khan ZK, Jain P. Antibody blockade of CLEC12A delays EAE onset and attenuates disease severity by impairing myeloid cell CNS infiltration and restoring positive immunity. Scientific Reports. 7: 2707. PMID 28578388 DOI: 10.1038/s41598-017-03027-x  0.92
2017 Andrews AM, Lutton EM, Cannella LA, Reichenbach N, Razmpour R, Seasock MJ, Kaspin SJ, Merkel SF, Langford D, Persidsky Y, Ramirez SH. Characterization of human fetal brain endothelial cells reveals barrier properties suitable for in vitro modeling of the BBB with syngenic co-cultures. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 271678X17708690. PMID 28534661 DOI: 10.1177/0271678X17708690  0.92
2017 Merkel SF, Cannella LA, Razmpour R, Lutton E, Raghupathi R, Rawls SM, Ramirez SH. Factors Affecting Increased Risk for Substance Use Disorders Following Traumatic Brain Injury: What We Can Learn from Animal Models. Neuroscience and Biobehavioral Reviews. PMID 28359860 DOI: 10.1016/j.neubiorev.2017.03.015  0.92
2016 Merkel SF, Andrews AM, Lutton EM, Mu D, Hudry E, Hyman BT, Maguire CA, Ramirez SH. Trafficking of AAV vectors across a model of the blood-brain barrier; a comparative study of transcytosis and transduction using primary human brain endothelial cells. Journal of Neurochemistry. PMID 27718541 DOI: 10.1111/jnc.13861  0.92
2016 Kawata K, Liu CY, Merkel SF, Ramirez SH, Tierney RT, Langford D. Blood Biomarkers for Brain Injury: What Are We Measuring? Neuroscience and Biobehavioral Reviews. PMID 27181909 DOI: 10.1016/j.neubiorev.2016.05.009  0.92
2016 Fernandes NC, Sriram U, Gofman L, Cenna JM, Ramirez SH, Potula R. Methamphetamine alters microglial immune function through P2X7R signaling. Journal of Neuroinflammation. 13: 91. PMID 27117066 DOI: 10.1186/s12974-016-0553-3  0.92
2016 Merkel SF, Razmpour R, Lutton EM, Tallarida CS, Heldt NA, Cannella LA, Persidsky Y, Rawls SM, Ramirez SH. Adolescent Traumatic Brain Injury Induces Chronic Mesolimbic Neuroinflammation with Concurrent Enhancement in the Rewarding Effects of Cocaine in Mice during Adulthood. Journal of Neurotrauma. PMID 27026056 DOI: 10.1089/neu.2015.4275  0.92
2016 Andrews AM, Lutton EM, Merkel SF, Razmpour R, Ramirez SH. Mechanical Injury Induces Brain Endothelial-Derived Microvesicle Release: Implications for Cerebral Vascular Injury during Traumatic Brain Injury. Frontiers in Cellular Neuroscience. 10: 43. PMID 26973460 DOI: 10.3389/fncel.2016.00043  0.92
2016 Hudry E, Martin C, Gandhi S, György B, Scheffer DI, Mu D, Merkel SF, Mingozzi F, Fitzpatrick Z, Dimant H, Masek M, Ragan T, Tan S, Brisson AR, Ramirez SH, et al. Exosome-associated AAV vector as a robust and convenient neuroscience tool. Gene Therapy. PMID 26836117 DOI: 10.1038/gt.2016.11  0.92
2015 Persidsky Y, Hill J, Zhang M, Dykstra H, Winfield M, Reichenbach NL, Potula R, Mukherjee A, Ramirez SH, Rom S. Dysfunction of brain pericytes in chronic neuroinflammation. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. PMID 26661157 DOI: 10.1177/0271678X15606149  0.92
2015 Wu L, Ramirez SH, Andrews AM, Leung W, Itoh K, Wu J, Arai K, Lo EH, Lok J. Neuregulin1-β decreases IL-1β induced RhoA activation, myosin light chain phosphorylation, and endothelial hyper-permeability. Journal of Neurochemistry. PMID 26438054 DOI: 10.1111/jnc.13374  0.92
2015 Sriram U, Cenna JM, Haldar B, Fernandes NC, Razmpour R, Fan S, Ramirez SH, Potula R. Methamphetamine induces trace amine-associated receptor 1 (TAAR1) expression in human T lymphocytes: role in immunomodulation. Journal of Leukocyte Biology. PMID 26302754 DOI: 10.1189/jlb.4A0814-395RR  0.92
2015 Watters AK, Rom S, Hill JD, Dematatis MK, Zhou Y, Merkel SF, Andrews AM, Cena J, Potula R, Skuba A, Son YJ, Persidsky Y, Ramirez SH. Identification and dynamic regulation of tight junction protein expression in human neural stem cells. Stem Cells and Development. 24: 1377-89. PMID 25892136 DOI: 10.1089/scd.2014.0497  0.92
2015 Persidsky Y, Fan S, Dykstra H, Reichenbach NL, Rom S, Ramirez SH. Activation of Cannabinoid Type Two Receptors (CB2) Diminish Inflammatory Responses in Macrophages and Brain Endothelium. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. 10: 302-8. PMID 25666933 DOI: 10.1007/s11481-015-9591-3  0.92
2015 Rom S, Zuluaga-Ramirez V, Dykstra H, Reichenbach NL, Ramirez SH, Persidsky Y. Poly(ADP-ribose) polymerase-1 inhibition in brain endothelium protects the blood-brain barrier under physiologic and neuroinflammatory conditions. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 35: 28-36. PMID 25248836 DOI: 10.1038/jcbfm.2014.167  0.92
2014 Maguire CA, Ramirez SH, Merkel SF, Sena-Esteves M, Breakefield XO. Gene therapy for the nervous system: challenges and new strategies. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. 11: 817-39. PMID 25159276 DOI: 10.1007/s13311-014-0299-5  0.92
2014 Hill J, Rom S, Ramirez SH, Persidsky Y. Emerging roles of pericytes in the regulation of the neurovascular unit in health and disease. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. 9: 591-605. PMID 25119834 DOI: 10.1007/s11481-014-9557-x  0.92
2014 Singh MV, Davidson DC, Jackson JW, Singh VB, Silva J, Ramirez SH, Maggirwar SB. Characterization of platelet-monocyte complexes in HIV-1-infected individuals: possible role in HIV-associated neuroinflammation. Journal of Immunology (Baltimore, Md. : 1950). 192: 4674-84. PMID 24729609 DOI: 10.4049/jimmunol.1302318  0.92
2013 Shuvaev VV, Han J, Tliba S, Arguiri E, Christofidou-Solomidou M, Ramirez SH, Dykstra H, Persidsky Y, Atochin DN, Huang PL, Muzykantov VR. Anti-inflammatory effect of targeted delivery of SOD to endothelium: mechanism, synergism with NO donors and protective effects in vitro and in vivo. Plos One. 8: e77002. PMID 24146950 DOI: 10.1371/journal.pone.0077002  0.92
2013 Ramirez SH, Reichenbach NL, Fan S, Rom S, Merkel SF, Wang X, Ho WZ, Persidsky Y. Attenuation of HIV-1 replication in macrophages by cannabinoid receptor 2 agonists. Journal of Leukocyte Biology. 93: 801-10. PMID 23463725 DOI: 10.1189/jlb.1012523  0.92
2013 Ramirez SH, Fan S, Dykstra H, Rom S, Mercer A, Reichenbach NL, Gofman L, Persidsky Y. Inhibition of glycogen synthase kinase 3β promotes tight junction stability in brain endothelial cells by half-life extension of occludin and claudin-5. Plos One. 8: e55972. PMID 23418486 DOI: 10.1371/journal.pone.0055972  0.92
2012 Rom S, Fan S, Reichenbach N, Dykstra H, Ramirez SH, Persidsky Y. Glycogen synthase kinase 3β inhibition prevents monocyte migration across brain endothelial cells via Rac1-GTPase suppression and down-regulation of active integrin conformation. The American Journal of Pathology. 181: 1414-25. PMID 22863953 DOI: 10.1016/j.ajpath.2012.06.018  0.92
2012 Ramirez SH, Haskó J, Skuba A, Fan S, Dykstra H, McCormick R, Reichenbach N, Krizbai I, Mahadevan A, Zhang M, Tuma R, Son YJ, Persidsky Y. Activation of cannabinoid receptor 2 attenuates leukocyte-endothelial cell interactions and blood-brain barrier dysfunction under inflammatory conditions. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 4004-16. PMID 22442067 DOI: 10.1523/JNEUROSCI.4628-11.2012  0.92
2012 Ye L, Wang X, Li J, Liu J, Ramirez SH, Wu J, Ho W. Tetherin has negligible activity in restricting hepatitis C virus in hepatocytes. Innate Immunity. 18: 398-405. PMID 21940748 DOI: 10.1177/1753425911412984  0.92
2011 Persidsky Y, Ho W, Ramirez SH, Potula R, Abood ME, Unterwald E, Tuma R. HIV-1 infection and alcohol abuse: neurocognitive impairment, mechanisms of neurodegeneration and therapeutic interventions. Brain, Behavior, and Immunity. 25: S61-70. PMID 21397004 DOI: 10.1016/j.bbi.2011.03.001  0.92
2010 Zhang M, Mao Y, Ramirez SH, Tuma RF, Chabrashvili T. Angiotensin II induced cerebral microvascular inflammation and increased blood-brain barrier permeability via oxidative stress. Neuroscience. 171: 852-8. PMID 20870012 DOI: 10.1016/j.neuroscience.2010.09.029  0.92
2010 Potula R, Hawkins BJ, Cenna JM, Fan S, Dykstra H, Ramirez SH, Morsey B, Brodie MR, Persidsky Y. Methamphetamine causes mitrochondrial oxidative damage in human T lymphocytes leading to functional impairment. Journal of Immunology (Baltimore, Md. : 1950). 185: 2867-76. PMID 20668216 DOI: 10.4049/jimmunol.0903691  0.92
2010 Ramirez SH, Fan S, Dykstra H, Reichenbach N, Del Valle L, Potula R, Phipps RP, Maggirwar SB, Persidsky Y. Dyad of CD40/CD40 ligand fosters neuroinflammation at the blood-brain barrier and is regulated via JNK signaling: implications for HIV-1 encephalitis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 9454-64. PMID 20631174 DOI: 10.1523/JNEUROSCI.5796-09.2010  0.92
2010 Bernas MJ, Cardoso FL, Daley SK, Weinand ME, Campos AR, Ferreira AJ, Hoying JB, Witte MH, Brites D, Persidsky Y, Ramirez SH, Brito MA. Establishment of primary cultures of human brain microvascular endothelial cells to provide an in vitro cellular model of the blood-brain barrier. Nature Protocols. 5: 1265-72. PMID 20595955 DOI: 10.1038/nprot.2010.76  0.92
2010 Ramirez SH, Fan S, Zhang M, Papugani A, Reichenbach N, Dykstra H, Mercer AJ, Tuma RF, Persidsky Y. Inhibition of glycogen synthase kinase 3beta (GSK3beta) decreases inflammatory responses in brain endothelial cells. The American Journal of Pathology. 176: 881-92. PMID 20056834 DOI: 10.2353/ajpath.2010.090671  0.92
2009 Ramirez SH, Potula R, Fan S, Eidem T, Papugani A, Reichenbach N, Dykstra H, Weksler BB, Romero IA, Couraud PO, Persidsky Y. Methamphetamine disrupts blood-brain barrier function by induction of oxidative stress in brain endothelial cells. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 29: 1933-45. PMID 19654589 DOI: 10.1038/jcbfm.2009.112  0.92
2009 Gendelman HE, Ding S, Gong N, Liu J, Ramirez SH, Persidsky Y, Mosley RL, Wang T, Volsky DJ, Xiong H. Monocyte chemotactic protein-1 regulates voltage-gated K+ channels and macrophage transmigration. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. 4: 47-59. PMID 19034671 DOI: 10.1007/s11481-008-9135-1  0.92
2008 Haorah J, Ramirez SH, Floreani N, Gorantla S, Morsey B, Persidsky Y. Mechanism of alcohol-induced oxidative stress and neuronal injury. Free Radical Biology & Medicine. 45: 1542-50. PMID 18845238 DOI: 10.1016/j.freeradbiomed.2008.08.030  0.92
2008 Potula R, Ramirez SH, Knipe B, Leibhart J, Schall K, Heilman D, Morsey B, Mercer A, Papugani A, Dou H, Persidsky Y. Peroxisome proliferator-activated receptor-gamma activation suppresses HIV-1 replication in an animal model of encephalitis. Aids (London, England). 22: 1539-49. PMID 18670212 DOI: 10.1097/QAD.0b013e3283081e08  0.92
2008 Ramirez SH, Heilman D, Morsey B, Potula R, Haorah J, Persidsky Y. Activation of peroxisome proliferator-activated receptor gamma (PPARgamma) suppresses Rho GTPases in human brain microvascular endothelial cells and inhibits adhesion and transendothelial migration of HIV-1 infected monocytes. Journal of Immunology (Baltimore, Md. : 1950). 180: 1854-65. PMID 18209083  0.92
2008 Yamamoto M, Ramirez SH, Sato S, Kiyota T, Cerny RL, Kaibuchi K, Persidsky Y, Ikezu T. Phosphorylation of claudin-5 and occludin by rho kinase in brain endothelial cells. The American Journal of Pathology. 172: 521-33. PMID 18187566 DOI: 10.2353/ajpath.2008.070076  0.92
2008 Haorah J, Schall K, Ramirez SH, Persidsky Y. Activation of protein tyrosine kinases and matrix metalloproteinases causes blood-brain barrier injury: Novel mechanism for neurodegeneration associated with alcohol abuse. Glia. 56: 78-88. PMID 17943953 DOI: 10.1002/glia.20596  0.92
2007 Liu J, Johnson TV, Lin J, Ramirez SH, Bronich TK, Caplan S, Persidsky Y, Gendelman HE, Kipnis J. T cell independent mechanism for copolymer-1-induced neuroprotection. European Journal of Immunology. 37: 3143-54. PMID 17948266 DOI: 10.1002/eji.200737398  0.92
2007 Haorah J, Ramirez SH, Schall K, Smith D, Pandya R, Persidsky Y. Oxidative stress activates protein tyrosine kinase and matrix metalloproteinases leading to blood-brain barrier dysfunction. Journal of Neurochemistry. 101: 566-76. PMID 17250680 DOI: 10.1111/j.1471-4159.2006.04393.x  0.92
2006 Persidsky Y, Ramirez SH, Haorah J, Kanmogne GD. Blood-brain barrier: structural components and function under physiologic and pathologic conditions. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. 1: 223-36. PMID 18040800 DOI: 10.1007/s11481-006-9025-3  0.92
2006 Maguire CA, Sapinoro R, Girgis N, Rodriguez-Colon SM, Ramirez SH, Williams J, Dewhurst S. Recombinant adenovirus type 5 vectors that target DC-SIGN, ChemR23 and alpha(v)beta3 integrin efficiently transduce human dendritic cells and enhance presentation of vectored antigens. Vaccine. 24: 671-82. PMID 16154247 DOI: 10.1016/j.vaccine.2005.08.038  0.92
2005 Fan S, Maguire CA, Ramirez SH, Bradel-Tretheway B, Sapinoro R, Sui Z, Chakraborty-Sett S, Dewhurst S. Valproic acid enhances gene expression from viral gene transfer vectors. Journal of Virological Methods. 125: 23-33. PMID 15737413 DOI: 10.1016/j.jviromet.2004.11.023  0.92
2004 Fan S, Ramirez SH, Garcia TM, Dewhurst S. Dishevelled promotes neurite outgrowth in neuronal differentiating neuroblastoma 2A cells, via a DIX-domain dependent pathway. Brain Research. Molecular Brain Research. 132: 38-50. PMID 15548427 DOI: 10.1016/j.molbrainres.2004.09.003  0.92
2004 Kovács AD, Chakraborty-Sett S, Ramirez SH, Sniderhan LF, Williamson AL, Maggirwar SB. Mechanism of NF-kappaB inactivation induced by survival signal withdrawal in cerebellar granule neurons. The European Journal of Neuroscience. 20: 345-52. PMID 15233744 DOI: 10.1111/j.1460-9568.2004.03493.x  0.92
2004 Ramirez SH, Fan S, Maguire CA, Perry S, Hardiek K, Ramkumar V, Gelbard HA, Dewhurst S, Maggirwar SB. Activation of adenosine A2A receptor protects sympathetic neurons against nerve growth factor withdrawal. Journal of Neuroscience Research. 77: 258-69. PMID 15211592 DOI: 10.1002/jnr.20150  0.92
2001 Ramirez SH, Sanchez JF, Dimitri CA, Gelbard HA, Dewhurst S, Maggirwar SB. Neurotrophins prevent HIV Tat-induced neuronal apoptosis via a nuclear factor-kappaB (NF-kappaB)-dependent mechanism. Journal of Neurochemistry. 78: 874-89. PMID 11520908 DOI: 10.1046/j.1471-4159.2001.00467.x  0.92
2001 Tong N, Sanchez JF, Maggirwar SB, Ramirez SH, Guo H, Dewhurst S, Gelbard HA. Activation of glycogen synthase kinase 3 beta (GSK-3beta) by platelet activating factor mediates migration and cell death in cerebellar granule neurons. The European Journal of Neuroscience. 13: 1913-22. PMID 11403684 DOI: 10.1046/j.0953-816X.2001.01572.x  0.92
2000 Maggirwar SB, Ramirez S, Tong N, Gelbard HA, Dewhurst S. Functional interplay between nuclear factor-kappaB and c-Jun integrated by coactivator p300 determines the survival of nerve growth factor-dependent PC12 cells. Journal of Neurochemistry. 74: 527-39. PMID 10646503 DOI: 10.1046/j.1471-4159.2000.740527.x  0.92
1999 Maggirwar SB, Tong N, Ramirez S, Gelbard HA, Dewhurst S. HIV-1 Tat-mediated activation of glycogen synthase kinase-3beta contributes to Tat-mediated neurotoxicity. Journal of Neurochemistry. 73: 578-86. PMID 10428053 DOI: 10.1046/j.1471-4159.1999.0730578.x  0.92
1996 Spilich GJ, Wannenmacher W, Duarte A, Buendia R, Gomez JT, Ramirez S, Anaya A, Otero E. Efficacy of pyritinol versus hydergine upon cognitive performance in patients with senile dementia of the Alzheimer's type: A double-blind multi-center trial Alzheimer's Research. 2: 79-84.  0.92
1992 Hanlon RE, Dobkin BH, Hadler B, Ramirez S, Cheska Y. Neurorehabilitation following right thalamic infarct: Effects of cognitive retraining on functional performance Journal of Clinical and Experimental Neuropsychology. 14: 433-447. PMID 1400910  0.92
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