Giulio M. Pasinetti, M.D., Ph.D. - Publications

Affiliations: 
Psychiatry Icahn School of Medicine at Mount Sinai, New York, NY, United States 
Area:
neurodegeneration, Alzheimer's disease
Website:
http://www.mountsinai.org/profiles/giulio-m-pasinetti

185 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Frolinger T, Sims S, Smith C, Wang J, Cheng H, Faith J, Ho L, Hao K, Pasinetti GM. The gut microbiota composition affects dietary polyphenols-mediated cognitive resilience in mice by modulating the bioavailability of phenolic acids. Scientific Reports. 9: 3546. PMID 30837576 DOI: 10.1038/s41598-019-39994-6  0.32
2018 Ho L, Zhao D, Ono K, Ruan K, Mogno I, Tsuji M, Carry E, Brathwaite J, Sims S, Frolinger T, Westfall S, Mazzola P, Wu Q, Hao K, Lloyd TE, ... ... Pasinetti GM, et al. Heterogeneity in gut microbiota drive polyphenol metabolism that influences α-synuclein misfolding and toxicity. The Journal of Nutritional Biochemistry. 64: 170-181. PMID 30530257 DOI: 10.1016/j.jnutbio.2018.10.019  0.32
2018 Zhao D, Yuan B, Carry E, Pasinetti GM, Ho L, Faith J, Mogno I, Simon J, Wu Q. Development and validation of an ultra-high performance liquid chromatography/triple quadrupole mass spectrometry method for analyzing microbial-derived grape polyphenol metabolites. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. 1099: 34-45. PMID 30241072 DOI: 10.1016/j.jchromb.2018.09.014  0.32
2018 Carry E, Zhao D, Mogno I, Faith J, Ho L, Villani T, Patel H, Pasinetti GM, Simon JE, Wu Q. Targeted analysis of microbial-generated phenolic acid metabolites derived from grape flavanols by gas chromatography-triple quadrupole mass spectrometry. Journal of Pharmaceutical and Biomedical Analysis. 159: 374-383. PMID 30032004 DOI: 10.1016/j.jpba.2018.06.034  0.32
2018 Wang J, Hodes GE, Zhang H, Zhang S, Zhao W, Golden SA, Bi W, Menard C, Kana V, Leboeuf M, Xie M, Bregman D, Pfau ML, Flanigan ME, Esteban-Fernández A, ... ... Pasinetti GM, et al. Epigenetic modulation of inflammation and synaptic plasticity promotes resilience against stress in mice. Nature Communications. 9: 477. PMID 29396460 DOI: 10.1038/s41467-017-02794-5  0.32
2017 Ho L, Ono K, Tsuji M, Mazzola P, Singh R, Pasinetti GM. Protective Roles of Intestinal Microbiota derived Short Chain Fatty Acids in Alzheimer's Disease-type Beta-Amyloid Neuropathological Mechanisms. Expert Review of Neurotherapeutics. PMID 29095058 DOI: 10.1080/14737175.2018.1400909  0.32
2017 Pasinetti GM, Ho L, Cheng H, Wang J, Simon JE, Wu QL, Zhao D, Carry E, Ferruzzi MG, Faith J, Valcarcel B, Hao K. A comprehensive database and analysis framework to incorporate multiscale data types and enable integrated analysis of bioactive polyphenols. Molecular Pharmaceutics. PMID 28665131 DOI: 10.1021/acs.molpharmaceut.7b00412  0.32
2017 Novotny JA, Chen TY, Terekhov AI, Gebauer SK, Baer DJ, Ho L, Pasinetti GM, Ferruzzi MG. The effect of obesity and repeated exposure on pharmacokinetic response to grape polyphenols in humans. Molecular Nutrition & Food Research. PMID 28654207 DOI: 10.1002/mnfr.201700043  0.32
2017 Chen TY, Ferruzzi MG, Wu QL, Simon JE, Talcott ST, Wang J, Ho L, Todd G, Cooper B, Pasinetti GM, Janle EM. Influence of diabetes on plasma pharmacokinetics and brain bioavailability of grape polyphenols and their phase ii metabolites in the Zucker diabetic fatty rat. Molecular Nutrition & Food Research. PMID 28568316 DOI: 10.1002/mnfr.201700111  0.32
2016 Ho L, Legere M, Li T, Levine S, Hao K, Valcarcel B, Pasinetti GM. Autonomic Nervous System Dysfunctions as a Basis for a Predictive Model of Risk of Neurological Disorders in Subjects with Prior History of Traumatic Brain Injury: Implications in Alzheimer's Disease. Journal of Alzheimer's Disease : Jad. PMID 27911325 DOI: 10.3233/JAD-160948  0.32
2016 Wang J, Bi W, Zhao W, Varghese M, Koch RJ, Walker RH, Chandraratna RA, Sanders ME, Janesick A, Blumberg B, Ward L, Ho L, Pasinetti GM. Selective brain penetrable Nurr1 transactivator for treating Parkinson's disease. Oncotarget. PMID 26862735 DOI: 10.18632/oncotarget.7191  1
2015 Dubner L, Wang J, Ho L, Ward L, Pasinetti GM. Recommendations for Development of New Standardized Forms of Cocoa Breeds and Cocoa Extract Processing for the Prevention of Alzheimer's Disease: Role of Cocoa in Promotion of Cognitive Resilience and Healthy Brain Aging. Journal of Alzheimer's Disease : Jad. PMID 26402120 DOI: 10.3233/JAD-150536  1
2015 Zhao W, Wang J, Bi W, Ferruzzi M, Yemul S, Freirea D, Mazzola P, Ho L, Dubner L, Pasinetti GM. Novel Application of Brain-Targeting Polyphenol Compounds in Sleep Deprivation-Induced Cognitive Dysfunction. Neurochemistry International. PMID 26235983 DOI: 10.1016/j.neuint.2015.07.023  1
2015 Hayden EY, Yamin G, Beroukhim S, Chen B, Kibalchenko M, Jiang L, Ho L, Wang J, Pasinetti GM, Teplow DB. Inhibiting amyloid β-protein assembly: Size-activity relationships among grape seed-derived polyphenols. Journal of Neurochemistry. PMID 26228682 DOI: 10.1111/jnc.13270  1
2015 Hao K, Di Narzo AF, Ho L, Luo W, Li S, Chen R, Li T, Dubner L, Pasinetti GM. Shared genetic etiology underlying alzheimer's Disease and type 2 Diabetes. Molecular Aspects of Medicine. PMID 26116273 DOI: 10.1016/j.mam.2015.06.006  1
2015 Xu Y, Simon JE, Welch C, Wightman JD, Ferruzzi MG, Ho L, Pasinetti GM, Wu Q. Correction to Survey of polyphenol constituents in grapes and grape-derived products. Journal of Agricultural and Food Chemistry. 63: 3804. PMID 25844621 DOI: 10.1021/acs.jafc.5b01552  1
2015 Zhao W, Wang J, Varghese M, Ho L, Mazzola P, Haroutunian V, Katsel PL, Gibson GE, Levine S, Dubner L, Pasinetti GM. Impaired mitochondrial energy metabolism as a novel risk factor for selective onset and progression of dementia in oldest-old subjects. Neuropsychiatric Disease and Treatment. 11: 565-74. PMID 25784811 DOI: 10.2147/NDT.S74898  1
2015 Pasinetti GM. Novel role of red wine-derived polyphenols in the prevention of Alzheimer's disease dementia and brain pathology: experimental approaches and clinical implications. Planta Medica. PMID 25760447 DOI: 10.1055/s-0035-1545846  1
2015 Wang D, Ho L, Faith J, Ono K, Janle EM, Lachcik PJ, Cooper BR, Jannasch AH, D'Arcy BR, Williams BA, Ferruzzi MG, Levine S, Zhao W, Dubner L, Pasinetti GM. Role of intestinal microbiota in the generation of polyphenol-derived phenolic acid mediated attenuation of Alzheimer's disease β-amyloid oligomerization. Molecular Nutrition & Food Research. 59: 1025-40. PMID 25689033 DOI: 10.1002/mnfr.201400544  1
2015 Blount JW, Redan BW, Ferruzzi MG, Reuhs BL, Cooper BR, Harwood JS, Shulaev V, Pasinetti G, Dixon RA. Synthesis and quantitative analysis of plasma-targeted metabolites of catechin and epicatechin. Journal of Agricultural and Food Chemistry. 63: 2233-40. PMID 25671729 DOI: 10.1021/jf505922b  1
2015 Mazzola P, Anzuini A, Picone D, De Filippi F, Dubner L, Bellelli G, Zatti G, Pasinetti GM, Annoni G. Simultaneous bilateral femoral neck fracture and end-stage renal disease in a 76-year-old woman: a case report. Aging Clinical and Experimental Research. 27: 555-9. PMID 25576255 DOI: 10.1007/s40520-014-0312-1  1
2015 Wang J, Freire D, Knable L, Zhao W, Gong B, Mazzola P, Ho L, Levine S, Pasinetti GM. Childhood and adolescent obesity and long-term cognitive consequences during aging. The Journal of Comparative Neurology. 523: 757-68. PMID 25380530 DOI: 10.1002/cne.23708  1
2015 Pasinetti GM, Wang J, Ho L, Zhao W, Dubner L. Roles of resveratrol and other grape-derived polyphenols in Alzheimer's disease prevention and treatment. Biochimica Et Biophysica Acta. 1852: 1202-1208. PMID 25315300 DOI: 10.1016/j.bbadis.2014.10.006  1
2015 Villani TS, Reichert W, Ferruzzi MG, Pasinetti GM, Simon JE, Wu Q. Chemical investigation of commercial grape seed derived products to assess quality and detect adulteration. Food Chemistry. 170: 271-80. PMID 25306345 DOI: 10.1016/j.foodchem.2014.08.084  1
2014 Ho L, Lange G, Zhao W, Wang J, Rooney R, Patel DH, Fobler MM, Helmer DA, Elder G, Shaughness MC, Ahlers ST, Russo SJ, Pasinetti GM. Select small nucleolar RNAs in blood components as novel biomarkers for improved identification of comorbid traumatic brain injury and post-traumatic stress disorder in veterans of the conflicts in Afghanistan and Iraq. American Journal of Neurodegenerative Disease. 3: 170-81. PMID 25628968  0.32
2014 Blumberg JB, Ding EL, Dixon R, Pasinetti GM, Villarreal F. The science of cocoa flavanols: bioavailability, emerging evidence, and proposed mechanisms. Advances in Nutrition (Bethesda, Md.). 5: 547-9. PMID 25469389 DOI: 10.3945/an.114.006478  1
2014 Gong B, Levine S, Barnum SR, Pasinetti GM. Role of complement systems in IVIG mediated attenuation of cognitive deterioration in Alzheimer's disease. Current Alzheimer Research. 11: 637-44. PMID 25115545  1
2014 Wang J, Varghese M, Ono K, Yamada M, Levine S, Tzavaras N, Gong B, Hurst WJ, Blitzer RD, Pasinetti GM. Cocoa extracts reduce oligomerization of amyloid-β: implications for cognitive improvement in Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 41: 643-50. PMID 24957018 DOI: 10.3233/JAD-132231  0.32
2014 Vidaurre OG, Haines JD, Katz Sand I, Adula KP, Huynh JL, McGraw CA, Zhang F, Varghese M, Sotirchos E, Bhargava P, Bandaru VV, Pasinetti G, Zhang W, Inglese M, Calabresi PA, et al. Cerebrospinal fluid ceramides from patients with multiple sclerosis impair neuronal bioenergetics. Brain : a Journal of Neurology. 137: 2271-86. PMID 24893707 DOI: 10.1093/brain/awu139  1
2014 Wang J, Bi W, Cheng A, Freire D, Vempati P, Zhao W, Gong B, Janle EM, Chen TY, Ferruzzi MG, Schmeidler J, Ho L, Pasinetti GM. Targeting multiple pathogenic mechanisms with polyphenols for the treatment of Alzheimer's disease-experimental approach and therapeutic implications. Frontiers in Aging Neuroscience. 6: 42. PMID 24672477 DOI: 10.3389/fnagi.2014.00042  1
2014 Wang J, Land D, Ono K, Galvez J, Zhao W, Vempati P, Steele JW, Cheng A, Yamada M, Levine S, Mazzola P, Pasinetti GM. Molecular topology as novel strategy for discovery of drugs with aβ lowering and anti-aggregation dual activities for Alzheimer's disease. Plos One. 9: e92750. PMID 24671215 DOI: 10.1371/journal.pone.0092750  1
2014 Fargali S, Garcia AL, Sadahiro M, Jiang C, Janssen WG, Lin WJ, Cogliani V, Elste A, Mortillo S, Cero C, Veitenheimer B, Graiani G, Pasinetti GM, Mahata SK, Osborn JW, et al. The granin VGF promotes genesis of secretory vesicles, and regulates circulating catecholamine levels and blood pressure. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 28: 2120-33. PMID 24497580 DOI: 10.1096/fj.13-239509  1
2014 Wang J, Gong B, Zhao W, Tang C, Varghese M, Nguyen T, Bi W, Bilski A, Begum S, Vempati P, Knable L, Ho L, Pasinetti GM. Epigenetic mechanisms linking diabetes and synaptic impairments. Diabetes. 63: 645-54. PMID 24154559 DOI: 10.2337/db13-1063  1
2014 Varghese M, Ho L, Wang J, Zhao W, Levine S, Ono K, Mannino S, Pasinetti GM. Green coffee as a novel agent for Alzheimer's disease prevention by attenuating diabetes Translational Neuroscience. 5: 111-116. DOI: 10.2478/s13380-014-0213-y  1
2013 Wang J, Tang C, Ferruzzi MG, Gong B, Song BJ, Janle EM, Chen TY, Cooper B, Varghese M, Cheng A, Freire D, Bilski A, Roman J, Nguyen T, Ho L, ... ... Pasinetti GM, et al. Role of standardized grape polyphenol preparation as a novel treatment to improve synaptic plasticity through attenuation of features of metabolic syndrome in a mouse model. Molecular Nutrition & Food Research. 57: 2091-102. PMID 23963661 DOI: 10.1002/mnfr.201300230  1
2013 Gong B, Pan Y, Zhao W, Knable L, Vempati P, Begum S, Ho L, Wang J, Yemul S, Barnum S, Bilski A, Gong BY, Pasinetti GM. IVIG immunotherapy protects against synaptic dysfunction in Alzheimer's disease through complement anaphylatoxin C5a-mediated AMPA-CREB-C/EBP signaling pathway. Molecular Immunology. 56: 619-29. PMID 23911420 DOI: 10.1016/j.molimm.2013.06.016  1
2013 Pasinetti GM, Bilski AE, Zhao W. Sirtuins as therapeutic targets of ALS. Cell Research. 23: 1073-4. PMID 23856645 DOI: 10.1038/cr.2013.94  1
2013 Wang J, Zhao Z, Lin E, Zhao W, Qian X, Freire D, Bilski AE, Cheng A, Vempati P, Ho L, Ono K, Yamada M, Pasinetti GM. Unintended effects of cardiovascular drugs on the pathogenesis of Alzheimer's disease. Plos One. 8: e65232. PMID 23762322 DOI: 10.1371/journal.pone.0065232  1
2013 Gong B, Pan Y, Vempati P, Zhao W, Knable L, Ho L, Wang J, Sastre M, Ono K, Sauve AA, Pasinetti GM. Nicotinamide riboside restores cognition through an upregulation of proliferator-activated receptor-γ coactivator 1α regulated β-secretase 1 degradation and mitochondrial gene expression in Alzheimer's mouse models. Neurobiology of Aging. 34: 1581-8. PMID 23312803 DOI: 10.1016/j.neurobiolaging.2012.12.005  1
2013 Zhao W, Ho L, Varghese M, Yemul S, Dams-O'Connor K, Gordon W, Knable L, Freire D, Haroutunian V, Pasinetti GM. Decreased level of olfactory receptors in blood cells following traumatic brain injury and potential association with tauopathy. Journal of Alzheimer's Disease : Jad. 34: 417-29. PMID 23241557 DOI: 10.3233/JAD-121894  1
2013 Wang J, Wright HM, Vempati P, Li H, Wangsa J, Dzhuan A, Habbu K, Knable LA, Ho L, Pasinetti GM. Investigation of nebivolol as a novel therapeutic agent for the treatment of Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 33: 1147-56. PMID 23128558 DOI: 10.3233/JAD-2012-120904  1
2013 Ho L, Ferruzzi MG, Janle EM, Wang J, Gong B, Chen TY, Lobo J, Cooper B, Wu QL, Talcott ST, Percival SS, Simon JE, Pasinetti GM. Identification of brain-targeted bioactive dietary quercetin-3-O-glucuronide as a novel intervention for Alzheimer's disease. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 27: 769-81. PMID 23097297 DOI: 10.1096/fj.12-212118  1
2012 Tang CY, Eaves E, Dams-O'Connor K, Ho L, Leung E, Wong E, Carpenter D, Ng J, Gordon W, Pasinetti G. Diffuse Disconnectivity in tBi: a resting state fMri anD Dti stuDy. Translational Neuroscience. 3: 9-14. PMID 23459252 DOI: 10.2478/s13380-012-0003-3  1
2012 Zhao W, Varghese M, Vempati P, Dzhun A, Cheng A, Wang J, Lange D, Bilski A, Faravelli I, Pasinetti GM. Caprylic triglyceride as a novel therapeutic approach to effectively improve the performance and attenuate the symptoms due to the motor neuron loss in ALS disease. Plos One. 7: e49191. PMID 23145119 DOI: 10.1371/journal.pone.0049191  1
2012 Pasinetti GM. Novel role of red wine-derived polyphenols in the prevention of Alzheimer's disease dementia and brain pathology: experimental approaches and clinical implications. Planta Medica. 78: 1614-9. PMID 23023952 DOI: 10.1055/s-0032-1315377  1
2012 Pasinetti GM, Ho L, Dooley C, Abbi B, Lange G. Select non-coding RNA in blood components provide novel clinically accessible biological surrogates for improved identification of traumatic brain injury in OEF/OIF Veterans. American Journal of Neurodegenerative Disease. 1: 88-98. PMID 22737634  0.32
2012 Ho L, Yemul S, Knable L, Katsel P, Zhao R, Haroutunian V, Pasinetti GM. Insulin receptor expression and activity in the brains of nondiabetic sporadic Alzheimer's disease cases. International Journal of Alzheimer's Disease. 2012: 321280. PMID 22666619 DOI: 10.1155/2012/321280  1
2012 Ho L, Zhao W, Dams-O'Connor K, Tang CY, Gordon W, Peskind ER, Yemul S, Haroutunian V, Pasinetti GM. Elevated plasma MCP-1 concentration following traumatic brain injury as a potential "predisposition" factor associated with an increased risk for subsequent development of Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 31: 301-13. PMID 22543850 DOI: 10.3233/JAD-2012-120598  1
2012 Wang J, Ferruzzi MG, Ho L, Blount J, Janle EM, Gong B, Pan Y, Gowda GA, Raftery D, Arrieta-Cruz I, Sharma V, Cooper B, Lobo J, Simon JE, Zhang C, ... ... Pasinetti GM, et al. Brain-targeted proanthocyanidin metabolites for Alzheimer's disease treatment. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 5144-50. PMID 22496560 DOI: 10.1523/JNEUROSCI.6437-11.2012  1
2012 Santa-Maria I, Varghese M, Ksiezak-Reding H, Dzhun A, Wang J, Pasinetti GM. Paired helical filaments from Alzheimer disease brain induce intracellular accumulation of Tau protein in aggresomes. The Journal of Biological Chemistry. 287: 20522-33. PMID 22496370 DOI: 10.1074/jbc.M111.323279  1
2012 Ho L, Varghese M, Wang J, Zhao W, Chen F, Knable LA, Ferruzzi M, Pasinetti GM. Dietary supplementation with decaffeinated green coffee improves diet-induced insulin resistance and brain energy metabolism in mice. Nutritional Neuroscience. 15: 37-45. PMID 22305652 DOI: 10.1179/1476830511Y.0000000027  1
2012 Blount JW, Ferruzzi M, Raftery D, Pasinetti GM, Dixon RA. Enzymatic synthesis of substituted epicatechins for bioactivity studies in neurological disorders. Biochemical and Biophysical Research Communications. 417: 457-61. PMID 22166210 DOI: 10.1016/j.bbrc.2011.11.139  1
2012 Santa-Maria I, Diaz-Ruiz C, Ksiezak-Reding H, Chen A, Ho L, Wang J, Pasinetti GM. GSPE interferes with tau aggregation in vivo: implication for treating tauopathy. Neurobiology of Aging. 33: 2072-81. PMID 22054871 DOI: 10.1016/j.neurobiolaging.2011.09.027  1
2012 Ksiezak-Reding H, Ho L, Santa-Maria I, Diaz-Ruiz C, Wang J, Pasinetti GM. Ultrastructural alterations of Alzheimer's disease paired helical filaments by grape seed-derived polyphenols. Neurobiology of Aging. 33: 1427-39. PMID 21196065 DOI: 10.1016/j.neurobiolaging.2010.11.006  1
2012 Xu Y, Simon JE, Ferruzzi MG, Ho L, Pasinetti GM, Wu Q. Quantification of anthocyanidins in the grapes and grape juice products with acid assisted hydrolysis using LC/MS Journal of Functional Foods. 4: 710-717. DOI: 10.1016/j.jff.2012.04.010  1
2011 Varghese M, Zhao W, Wang J, Cheng A, Qian X, Chaudhry A, Ho L, Pasinetti GM. Mitochondrial bioenergetics is defective in presymptomatic Tg2576 AD mice. Translational Neuroscience. 2. PMID 24286008 DOI: 10.2478/s13380-011-0011-8  1
2011 Pasinetti GM, Wang J, Marambaud P, Ferruzzi M, Gregor P, Knable LA, Ho L. Neuroprotective and metabolic effects of resveratrol: therapeutic implications for Huntington's disease and other neurodegenerative disorders. Experimental Neurology. 232: 1-6. PMID 21907197 DOI: 10.1016/j.expneurol.2011.08.014  1
2011 Pasinetti GM, Wang J, Porter S, Ho L. Caloric intake, dietary lifestyles, macronutrient composition, and alzheimer' disease dementia. International Journal of Alzheimer's Disease. 2011: 806293. PMID 21808725 DOI: 10.4061/2011/806293  1
2011 Zhao W, Varghese M, Yemul S, Pan Y, Cheng A, Marano P, Hassan S, Vempati P, Chen F, Qian X, Pasinetti GM. Peroxisome proliferator activator receptor gamma coactivator-1alpha (PGC-1α) improves motor performance and survival in a mouse model of amyotrophic lateral sclerosis. Molecular Neurodegeneration. 6: 51. PMID 21771318 DOI: 10.1186/1750-1326-6-51  1
2011 Liu P, Kemper LJ, Wang J, Zahs KR, Ashe KH, Pasinetti GM. Grape seed polyphenolic extract specifically decreases aβ*56 in the brains of Tg2576 mice. Journal of Alzheimer's Disease : Jad. 26: 657-66. PMID 21743132 DOI: 10.3233/JAD-2011-110383  1
2011 Wang J, Ferruzzi MG, Varghese M, Qian X, Cheng A, Xie M, Zhao W, Ho L, Pasinetti GM. Preclinical study of dimebon on β-amyloid-mediated neuropathology in Alzheimer's disease. Molecular Neurodegeneration. 6: 7. PMID 21247479 DOI: 10.1186/1750-1326-6-7  1
2011 Wang J, Ono K, Dickstein DL, Arrieta-Cruz I, Zhao W, Qian X, Lamparello A, Subnani R, Ferruzzi M, Pavlides C, Ho L, Hof PR, Teplow DB, Pasinetti GM. Carvedilol as a potential novel agent for the treatment of Alzheimer's disease. Neurobiology of Aging. 32: 2321.e1-12. PMID 20579773 DOI: 10.1016/j.neurobiolaging.2010.05.004  1
2011 Ho L, Chen LH, Wang J, Zhao W, Talcott ST, Ono K, Teplow D, Humala N, Cheng A, Percival SS, Ferruzzi M, Janle E, Dickstein DL, Pasinetti GM. Heterogeneity in red wine polyphenolic contents differentially influences Alzheimer's disease-type neuropathology and cognitive deterioration Advances in Alzheimer's Disease. 1: 263-275. DOI: 10.3233/978-1-60750-733-8-263  1
2011 Fivecoat HC, Pasinetti GM. Caloric intake, dietary lifestyles, macronutrient composition and dementia Lifetime Nutritional Influences On Cognition, Behaviour and Psychiatric Illness. 439-463. DOI: 10.1533/9780857092922.3.439  1
2011 Bartolomucci A, Pasinetti GM, Salton SRJ. Corrigendum to "Granins as disease-biomarkers: Translational potential for psychiatric and neurological disorders,". [Neuroscience 170/1 (2010) 289-297] Neuroscience. 172: 580. DOI: 10.1016/j.neuroscience.2010.10.053  1
2011 Pasinetti GM. The Protective Role of Grape Seed Polyphenols Against Oxidative Stress in Treating Neurodegenerative Diseases Oxidative Stress in Vertebrates and Invertebrates: Molecular Aspects of Cell Signaling. 235-243. DOI: 10.1002/9781118148143.ch16  1
2010 Pasinetti GM, Ho L. Role of grape seed polyphenols in Alzheimer's disease neuropathology. Nutrition and Dietary Supplements. 2010: 97-103. PMID 23730149 DOI: 10.2147/NDS.S6898  0.32
2010 Wang J, Pfleger CM, Friedman L, Vittorino R, Zhao W, Qian X, Conley L, Ho L, Pasinetti GM. POTENTIAL APPLICATION OF GRAPE DERIVED POLYPHENOLS IN HUNTINGTON'S DISEASE. Translational Neuroscience. 1: 95-100. PMID 21331299 DOI: 10.2478/v10134-010-0022-y  1
2010 Pasinetti GM, Fivecoat H, Ho L. Personalized medicine in traumatic brain injury. The Psychiatric Clinics of North America. 33: 905-13. PMID 21093685 DOI: 10.1016/j.psc.2010.09.003  1
2010 Dixon RA, Pasinetti GM. Flavonoids and isoflavonoids: from plant biology to agriculture and neuroscience. Plant Physiology. 154: 453-7. PMID 20921162 DOI: 10.1104/pp.110.161430  1
2010 Pfleger CM, Wang J, Friedman L, Vittorino R, Conley LM, Ho L, Fivecoat HC, Pasinetti GM. Grape-seed polyphenolic extract improves the eye phenotype in a Drosophila model of tauopathy. International Journal of Alzheimer's Disease. 2010. PMID 20871666 DOI: 10.4061/2010/576357  1
2010 Wang J, Santa-Maria I, Ho L, Ksiezak-Reding H, Ono K, Teplow DB, Pasinetti GM. Grape derived polyphenols attenuate tau neuropathology in a mouse model of Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 22: 653-61. PMID 20858961 DOI: 10.3233/JAD-2010-101074  1
2010 Gong B, Chen F, Pan Y, Arrieta-Cruz I, Yoshida Y, Haroutunian V, Pasinetti GM. SCFFbx2-E3-ligase-mediated degradation of BACE1 attenuates Alzheimer's disease amyloidosis and improves synaptic function. Aging Cell. 9: 1018-31. PMID 20854419 DOI: 10.1111/j.1474-9726.2010.00632.x  1
2010 Ho L, Pasinetti GM. Polyphenolic compounds for treating neurodegenerative disorders involving protein misfolding. Expert Review of Proteomics. 7: 579-89. PMID 20653511 DOI: 10.1586/epr.10.69  1
2010 Bartolomucci A, Pasinetti GM, Salton SR. Granins as disease-biomarkers: translational potential for psychiatric and neurological disorders. Neuroscience. 170: 289-97. PMID 20600637 DOI: 10.1016/j.neuroscience.2010.06.057  1
2010 Arrieta-Cruz I, Wang J, Pavlides C, Pasinetti GM. Carvedilol reestablishes long-term potentiation in a mouse model of Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 21: 649-54. PMID 20571219 DOI: 10.3233/JAD-2010-100225  1
2010 Pasinetti GM, Ksiezak-Reding H, Santa-Maria I, Wang J, Ho L. Development of a grape seed polyphenolic extract with anti-oligomeric activity as a novel treatment in progressive supranuclear palsy and other tauopathies. Journal of Neurochemistry. 114: 1557-68. PMID 20569300 DOI: 10.1111/j.1471-4159.2010.06875.x  1
2010 Wang J, Fivecoat H, Ho L, Pan Y, Ling E, Pasinetti GM. The role of Sirt1: at the crossroad between promotion of longevity and protection against Alzheimer's disease neuropathology. Biochimica Et Biophysica Acta. 1804: 1690-4. PMID 19945548 DOI: 10.1016/j.bbapap.2009.11.015  1
2010 Ho L, Fivecoat H, Wang J, Pasinetti GM. Alzheimer's disease biomarker discovery in symptomatic and asymptomatic patients: experimental approaches and future clinical applications. Experimental Gerontology. 45: 15-22. PMID 19796674 DOI: 10.1016/j.exger.2009.09.007  1
2010 Arrieta-Cruz I, Pavlides C, Pasinetti GM. Deep brain stimulation facilitates memory in a model of alzheimer's disease Translational Neuroscience. 1: 170-176. DOI: 10.2478/v10134-010-0026-7  1
2010 Ling E, Shrikhande RA, Pasinetti GM. Neurotransmitters and growth factors: Overview Encyclopedia of Neuroscience. 1073-1083. DOI: 10.1016/B978-008045046-9.00139-X  1
2009 Díaz-Ruiz C, Wang J, Ksiezak-Reding H, Ho L, Qian X, Humala N, Thomas S, Martínez-Martín P, Pasinetti GM. Role of Hypertension in Aggravating Abeta Neuropathology of AD Type and Tau-Mediated Motor Impairment. Cardiovascular Psychiatry and Neurology. 2009: 107286. PMID 19936102 DOI: 10.1155/2009/107286  0.32
2009 Pedrini S, Thomas C, Brautigam H, Schmeidler J, Ho L, Fraser P, Westaway D, Hyslop PS, Martins RN, Buxbaum JD, Pasinetti GM, Dickstein DL, Hof PR, Ehrlich ME, Gandy S. Dietary composition modulates brain mass and solubilizable Abeta levels in a mouse model of aggressive Alzheimer's amyloid pathology. Molecular Neurodegeneration. 4: 40. PMID 19845940 DOI: 10.1186/1750-1326-4-40  1
2009 Ferruzzi MG, Lobo JK, Janle EM, Cooper B, Simon JE, Wu QL, Welch C, Ho L, Weaver C, Pasinetti GM. Bioavailability of gallic acid and catechins from grape seed polyphenol extract is improved by repeated dosing in rats: implications for treatment in Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 18: 113-24. PMID 19625746 DOI: 10.3233/JAD-2009-1135  1
2009 Qin W, Haroutunian V, Katsel P, Cardozo CP, Ho L, Buxbaum JD, Pasinetti GM. PGC-1alpha expression decreases in the Alzheimer disease brain as a function of dementia. Archives of Neurology. 66: 352-61. PMID 19273754 DOI: 10.1001/archneurol.2008.588  1
2009 Ho L, Yemul S, Wang J, Pasinetti GM. Grape seed polyphenolic extract as a potential novel therapeutic agent in tauopathies. Journal of Alzheimer's Disease : Jad. 16: 433-9. PMID 19221432 DOI: 10.3233/JAD-2009-0969  1
2009 Amadio M, Pascale A, Wang J, Ho L, Quattrone A, Gandy S, Haroutunian V, Racchi M, Pasinetti GM. nELAV proteins alteration in Alzheimer's disease brain: a novel putative target for amyloid-beta reverberating on AbetaPP processing. Journal of Alzheimer's Disease : Jad. 16: 409-19. PMID 19221430 DOI: 10.3233/JAD-2009-0967  1
2009 Qin W, Ho L, Wang J, Peskind E, Pasinetti GM. S100A7, a novel Alzheimer's disease biomarker with non-amyloidogenic alpha-secretase activity acts via selective promotion of ADAM-10. Plos One. 4: e4183. PMID 19159013 DOI: 10.1371/journal.pone.0004183  1
2009 Ho L, Chen LH, Wang J, Zhao W, Talcott ST, Ono K, Teplow D, Humala N, Cheng A, Percival SS, Ferruzzi M, Janle E, Dickstein DL, Pasinetti GM. Heterogeneity in red wine polyphenolic contents differentially influences Alzheimer's disease-type neuropathology and cognitive deterioration. Journal of Alzheimer's Disease : Jad. 16: 59-72. PMID 19158422 DOI: 10.3233/JAD-2009-0916  1
2009 Zhao W, Wang J, Ho L, Ono K, Teplow DB, Pasinetti GM. Identification of antihypertensive drugs which inhibit amyloid-beta protein oligomerization. Journal of Alzheimer's Disease : Jad. 16: 49-57. PMID 19158421 DOI: 10.3233/JAD-2009-0925  1
2008 Pasinetti GM, Hiller-Sturmhöfel S. Systems biology in the study of neurological disorders: focus on Alzheimer's disease. Alcohol Research & Health : the Journal of the National Institute On Alcohol Abuse and Alcoholism. 31: 60-5. PMID 23584752  1
2008 Qin W, Zhao W, Ho L, Wang J, Walsh K, Gandy S, Pasinetti GM. Regulation of forkhead transcription factor FoxO3a contributes to calorie restriction-induced prevention of Alzheimer's disease-type amyloid neuropathology and spatial memory deterioration. Annals of the New York Academy of Sciences. 1147: 335-47. PMID 19076455 DOI: 10.1196/annals.1427.024  1
2008 Ono K, Condron MM, Ho L, Wang J, Zhao W, Pasinetti GM, Teplow DB. Effects of grape seed-derived polyphenols on amyloid beta-protein self-assembly and cytotoxicity. The Journal of Biological Chemistry. 283: 32176-87. PMID 18815129 DOI: 10.1074/jbc.M806154200  1
2008 Wang J, Ho L, Zhao W, Ono K, Rosensweig C, Chen L, Humala N, Teplow DB, Pasinetti GM. Grape-derived polyphenolics prevent Abeta oligomerization and attenuate cognitive deterioration in a mouse model of Alzheimer's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 6388-92. PMID 18562609 DOI: 10.1523/JNEUROSCI.0364-08.2008  1
2008 Pasinetti GM, Eberstein JA. Metabolic syndrome and the role of dietary lifestyles in Alzheimer's disease. Journal of Neurochemistry. 106: 1503-14. PMID 18466323 DOI: 10.1111/j.1471-4159.2008.05454.x  1
2008 Zhao Z, Lange DJ, Ho L, Bonini S, Shao B, Salton SR, Thomas S, Pasinetti GM. Vgf is a novel biomarker associated with muscle weakness in amyotrophic lateral sclerosis (ALS), with a potential role in disease pathogenesis. International Journal of Medical Sciences. 5: 92-9. PMID 18432310  1
2008 Sharma N, Thomas S, Ho L, Reyes DC, Sacerdote P, Bianchi M, Pasinetti GM. Immunomodulation with glatiramer acetate prevents long-term inflammatory pain. The International Journal of Neuroscience. 118: 433-53. PMID 18300014 DOI: 10.1080/00207450701849018  1
2008 Mukherjee P, Thomas S, Pasinetti GM. Complement anaphylatoxin C5a neuroprotects through regulation of glutamate receptor subunit 2 in vitro and in vivo. Journal of Neuroinflammation. 5: 5. PMID 18230183 DOI: 10.1186/1742-2094-5-5  1
2008 Pasinetti GM. Can diet modifications play a preventative role in the onset of Alzheimer's disease? Aging Health. 4: 1-3. DOI: 10.2217/1745509X.4.1.1  1
2007 Xiang Z, Thomas S, Pasinetti G. Increased neuronal injury in transgenic mice with neuronal overexpression of human cyclooxygenase-2 is reversed by hypothermia and rofecoxib treatment Current Neurovascular Research. 4: 274-279. PMID 18045153 DOI: 10.2174/156720207782446342  1
2007 Wang J, Ho L, Chen L, Zhao Z, Zhao W, Qian X, Humala N, Seror I, Bartholomew S, Rosendorff C, Pasinetti GM. Valsartan lowers brain beta-amyloid protein levels and improves spatial learning in a mouse model of Alzheimer disease. The Journal of Clinical Investigation. 117: 3393-402. PMID 17965777 DOI: 10.1172/JCI31547  1
2007 Pasinetti GM, Zhao Z, Qin W, Ho L, Shrishailam Y, Macgrogan D, Ressmann W, Humala N, Liu X, Romero C, Stetka B, Chen L, Ksiezak-Reding H, Wang J. Caloric intake and Alzheimer's disease. Experimental approaches and therapeutic implications. Interdisciplinary Topics in Gerontology. 35: 159-75. PMID 17063038 DOI: 10.1159/000096561  1
2007 Zhao Z, Xiang Z, Haroutunian V, Buxbaum JD, Stetka B, Pasinetti GM. Insulin degrading enzyme activity selectively decreases in the hippocampal formation of cases at high risk to develop Alzheimer's disease. Neurobiology of Aging. 28: 824-30. PMID 16769157 DOI: 10.1016/j.neurobiolaging.2006.05.001  1
2006 Qin W, Chachich M, Lane M, Roth G, Bryant M, de Cabo R, Ottinger MA, Mattison J, Ingram D, Gandy S, Pasinetti GM. Calorie restriction attenuates Alzheimer's disease type brain amyloidosis in Squirrel monkeys (Saimiri sciureus). Journal of Alzheimer's Disease : Jad. 10: 417-22. PMID 17183154  1
2006 Takahashi M, Uchikado H, Caprotti D, Weidenheim KM, Dickson DW, Ksiezak-Reding H, Pasinetti GM. Identification of G-protein coupled receptor kinase 2 in paired helical filaments and neurofibrillary tangles. Journal of Neuropathology and Experimental Neurology. 65: 1157-69. PMID 17146290 DOI: 10.1097/01.jnen.0000248542.82681.12  1
2006 Wang J, Ho L, Zhao Z, Seror I, Humala N, Dickstein DL, Thiyagarajan M, Percival SS, Talcott ST, Pasinetti GM. Moderate consumption of Cabernet Sauvignon attenuates Abeta neuropathology in a mouse model of Alzheimer's disease. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 20: 2313-20. PMID 17077308 DOI: 10.1096/fj.06-6281com  1
2006 Qin W, Yang T, Ho L, Zhao Z, Wang J, Chen L, Zhao W, Thiyagarajan M, MacGrogan D, Rodgers JT, Puigserver P, Sadoshima J, Deng H, Pedrini S, Gandy S, ... ... Pasinetti GM, et al. Neuronal SIRT1 activation as a novel mechanism underlying the prevention of Alzheimer disease amyloid neuropathology by calorie restriction. The Journal of Biological Chemistry. 281: 21745-54. PMID 16751189 DOI: 10.1074/jbc.M602909200  1
2006 Zhao Z, Lange DJ, Voustianiouk A, MacGrogan D, Ho L, Suh J, Humala N, Thiyagarajan M, Wang J, Pasinetti GM. A ketogenic diet as a potential novel therapeutic intervention in amyotrophic lateral sclerosis. Bmc Neuroscience. 7: 29. PMID 16584562 DOI: 10.1186/1471-2202-7-29  1
2006 Zhao Z, Ksiezak-Reding H, Riggio S, Haroutunian V, Pasinetti GM. Insulin receptor deficits in schizophrenia and in cellular and animal models of insulin receptor dysfunction. Schizophrenia Research. 84: 1-14. PMID 16581231 DOI: 10.1016/j.schres.2006.02.009  1
2006 Pasinetti GM, Ungar LH, Lange DJ, Yemul S, Deng H, Yuan X, Brown RH, Cudkowicz ME, Newhall K, Peskind E, Marcus S, Ho L. Identification of potential CSF biomarkers in ALS. Neurology. 66: 1218-22. PMID 16481598 DOI: 10.1212/01.wnl.0000203129.82104.07  1
2006 Ho L, Qin W, Stetka BS, Pasinetti GM. Is there a future for cyclo-oxygenase inhibitors in Alzheimer's disease? Cns Drugs. 20: 85-98. PMID 16478285 DOI: 10.2165/00023210-200620020-00001  1
2006 Xiang Z, Haroutunian V, Ho L, Purohit D, Pasinetti GM. Microglia activation in the brain as inflammatory biomarker of Alzheimer's disease neuropathology and clinical dementia. Disease Markers. 22: 95-102. PMID 16410654  1
2006 Qin W, Peng Y, Ksiezak-Reding H, Ho L, Stetka B, Lovati E, Pasinetti GM. Inhibition of cyclooxygenase as potential novel therapeutic strategy in N141I presenilin-2 familial Alzheimer's disease. Molecular Psychiatry. 11: 172-81. PMID 16331303 DOI: 10.1038/sj.mp.4001773  1
2005 Zhao Z, Ho L, Wang J, Qin W, Festa ED, Mobbs C, Hof P, Rocher A, Masur S, Haroutunian V, Pasinetti GM. Connective tissue growth factor (CTGF) expression in the brain is a downstream effector of insulin resistance- associated promotion of Alzheimer's disease beta-amyloid neuropathology. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 19: 2081-2. PMID 16186174 DOI: 10.1096/fj.05-4359fje  1
2005 Ho L, Sharma N, Blackman L, Festa E, Reddy G, Pasinetti GM. From proteomics to biomarker discovery in Alzheimer's disease. Brain Research. Brain Research Reviews. 48: 360-9. PMID 15850675 DOI: 10.1016/j.brainresrev.2004.12.025  1
2005 Zhao Z, Ksiezak-Reding H, Wang J, Pasinetti GM. Expression of tau reduces secretion of Abeta without altering the amyloid precursor protein content in CHOsw cells. Febs Letters. 579: 2119-24. PMID 15811328 DOI: 10.1016/j.febslet.2005.02.067  1
2005 Wang J, Ho L, Qin W, Rocher AB, Seror I, Humala N, Maniar K, Dolios G, Wang R, Hof PR, Pasinetti GM. Caloric restriction attenuates beta-amyloid neuropathology in a mouse model of Alzheimer's disease. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 19: 659-61. PMID 15650008 DOI: 10.1096/fj.04-3182fje  1
2005 Pasinetti GM. The role of inflammation in Alzheimer's disease neuropathology and clinical dementia. From epidemiology to treatment Neurodegenerative Diseases: Neurobiology, Pathogenesis and Therapeutics. 166-175. DOI: 10.1017/CBO9780511544873.015  1
2004 Kyoung Pyo H, Lovati E, Pasinetti GM, Ksiezak-Reding H. Phosphorylation of tau at THR212 and SER214 in human neuronal and glial cultures: the role of AKT. Neuroscience. 127: 649-58. PMID 15283964 DOI: 10.1016/j.neuroscience.2004.05.036  1
2004 Ho L, Qin W, Pompl PN, Xiang Z, Wang J, Zhao Z, Peng Y, Cambareri G, Rocher A, Mobbs CV, Hof PR, Pasinetti GM. Diet-induced insulin resistance promotes amyloidosis in a transgenic mouse model of Alzheimer's disease. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 18: 902-4. PMID 15033922 DOI: 10.1096/fj.03-0978fje  1
2004 Zhao H, Jhanwar-Uniyal M, Datta PK, Yemul S, Ho L, Khitrov G, Kupershmidt I, Pasinetti GM, Ray T, Athwal RS, Achary MP. Expression profile of genes associated with antimetastatic gene: nm23-mediated metastasis inhibition in breast carcinoma cells. International Journal of Cancer. Journal International Du Cancer. 109: 65-70. PMID 14735469 DOI: 10.1002/ijc.11676  1
2003 Ksiezak-Reding H, Pyo HK, Feinstein B, Pasinetti GM. Akt/PKB kinase phosphorylates separately Thr212 and Ser214 of tau protein in vitro. Biochimica Et Biophysica Acta. 1639: 159-68. PMID 14636947 DOI: 10.1016/j.bbadis.2003.09.001  1
2003 Mizuno TM, Kelley KA, Pasinetti GM, Roberts JL, Mobbs CV. Transgenic neuronal expression of proopiomelanocortin attenuates hyperphagic response to fasting and reverses metabolic impairments in leptin-deficient obese mice. Diabetes. 52: 2675-83. PMID 14578285 DOI: 10.2337/diabetes.52.11.2675  1
2003 Zhao Z, Ho L, Suh J, Qin W, Pyo H, Pompl P, Ksiezak-Reding H, Pasinetti GM. A role of P301L tau mutant in anti-apoptotic gene expression, cell cycle and apoptosis. Molecular and Cellular Neurosciences. 24: 367-79. PMID 14572459 DOI: 10.1016/S1044-7431(03)00175-1  1
2003 Qin W, Ho L, Pompl PN, Peng Y, Zhao Z, Xiang Z, Robakis NK, Shioi J, Suh J, Pasinetti GM. Cyclooxygenase (COX)-2 and COX-1 potentiate beta-amyloid peptide generation through mechanisms that involve gamma-secretase activity. The Journal of Biological Chemistry. 278: 50970-7. PMID 14507922 DOI: 10.1074/jbc.M307699200  1
2003 Gineste C, Ho L, Pompl P, Bianchi M, Pasinetti GM. High-throughput proteomics and protein biomarker discovery in an experimental model of inflammatory hyperalgesia: effects of nimesulide. Drugs. 63: 23-9. PMID 14506908  1
2003 Pompl PN, Yemul S, Xiang Z, Ho L, Haroutunian V, Purohit D, Mohs R, Pasinetti GM. Caspase gene expression in the brain as a function of the clinical progression of Alzheimer disease. Archives of Neurology. 60: 369-76. PMID 12633148 DOI: 10.1001/archneur.60.3.369  1
2003 Pompl PN, Ho L, Bianchi M, McManus T, Qin W, Pasinetti GM. A therapeutic role for cyclooxygenase-2 inhibitors in a transgenic mouse model of amyotrophic lateral sclerosis. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 17: 725-7. PMID 12586733 DOI: 10.1096/fj.02-0876fje  1
2002 Pasinetti GM, Pompl PN. Cyclo-oxygenase inhibitors and Alzheimer's: are we well ADAPTed? The Lancet. Neurology. 1: 403-4. PMID 12849357 DOI: 10.1016/S1474-4422(02)00214-4  1
2002 Pasinetti GM. Cyclooxygenase as a target for the antiamyloidogenic activities of nonsteroidal anti-inflammatory drugs in Alzheimer's disease. Neuro-Signals. 11: 293-7. PMID 12566930 DOI: 10.1159/000067428  1
2002 Xiang Z, Ho L, Yemul S, Zhao Z, Qing W, Pompl P, Kelley K, Dang A, Qing W, Teplow D, Pasinetti GM. Cyclooxygenase-2 promotes amyloid plaque deposition in a mouse model of Alzheimer's disease neuropathology. Gene Expression. 10: 271-8. PMID 12450219  1
2002 Pasinetti GM. From epidemiology to therapeutic trials with anti-inflammatory drugs in Alzheimer's disease: the role of NSAIDs and cyclooxygenase in beta-amyloidosis and clinical dementia. Journal of Alzheimer's Disease : Jad. 4: 435-45. PMID 12446975  1
2002 Pasinetti GM, Ho L, Pompl P. Amyloid immunization in Alzheimer's disease: do we promote amyloid scavenging at the cost of inflammatory degeneration? Neurobiology of Aging. 23: 665-6. PMID 12392767 DOI: 10.1016/S0197-4580(02)00007-6  1
2002 Butterfield DA, Griffin S, Munch G, Pasinetti GM. Amyloid beta-peptide and amyloid pathology are central to the oxidative stress and inflammatory cascades under which Alzheimer's disease brain exists. Journal of Alzheimer's Disease : Jad. 4: 193-201. PMID 12226538  1
2002 Mukherjee P, Pasinetti GM. Altered gene expression during nimesulide-mediated inhibition of apoptotic death in human chondrocytes. International Journal of Clinical Practice. Supplement. 20-3. PMID 12166615  1
2002 Wen PH, Shao X, Shao Z, Hof PR, Wisniewski T, Kelley K, Friedrich VL, Ho L, Pasinetti GM, Shioi J, Robakis NK, Elder GA. Overexpression of wild type but not an FAD mutant presenilin-1 promotes neurogenesis in the hippocampus of adult mice. Neurobiology of Disease. 10: 8-19. PMID 12079399 DOI: 10.1006/nbdi.2002.0490  1
2002 Mirjany M, Ho L, Pasinetti GM. Role of cyclooxygenase-2 in neuronal cell cycle activity and glutamate-mediated excitotoxicity. The Journal of Pharmacology and Experimental Therapeutics. 301: 494-500. PMID 11961048 DOI: 10.1124/jpet.301.2.494  1
2002 Xiang Z, Ho L, Valdellon J, Borchelt D, Kelley K, Spielman L, Aisen PS, Pasinetti GM. Cyclooxygenase (COX)-2 and cell cycle activity in a transgenic mouse model of Alzheimer's disease neuropathology. Neurobiology of Aging. 23: 327-34. PMID 11959394 DOI: 10.1016/S0197-4580(01)00282-2  1
2002 Aisen PS, Schmeidler J, Pasinetti GM. Randomized pilot study of nimesulide treatment in Alzheimer's disease. Neurology. 58: 1050-4. PMID 11940691  1
2002 Spielman L, Winger D, Ho L, Aisen PS, Shohami E, Pasinetti GM. Induction of the complement component C1qB in brain of transgenic mice with neuronal overexpression of human cyclooxygenase-2. Acta Neuropathologica. 103: 157-62. PMID 11810182 DOI: 10.1007/s004010100447  1
2002 Pasinetti GM, Ho L, Pompl P. AN1792 vaccination immunotherapy in Alzheimer's disease: The case of a therapy before its time Neurobiology of Aging. 23: 683-684. DOI: 10.1016/S0197-4580(02)00081-7  1
2002 Pasinetti GM. From cyclooxygenase activities to Alzheimer's disease neuropathology: Experimental approaches and therapeutic interventions Drug Development Research. 56: 438-445. DOI: 10.1002/ddr.10096  1
2001 Ho L, Pasinetti GM. The potential of selective COX-2 inhibitors in inflammatory and other diseases. Drugs of Today (Barcelona, Spain : 1998). 37: 181-185. PMID 12783090  1
2001 Pasinetti GM, Ho L. From cDNA microarrays to high-throughput proteomics. Implications in the search for preventive initiatives to slow the clinical progression of Alzheimer's disease dementia. Restorative Neurology and Neuroscience. 18: 137-42. PMID 11847436  1
2001 Pasinetti GM. Use of cDNA microarray in the search for molecular markers involved in the onset of Alzheimer's disease dementia. Journal of Neuroscience Research. 65: 471-6. PMID 11550214 DOI: 10.1002/jnr.1176  1
2001 Ho L, Xiang Z, Mukherjee P, Zhang W, De Jesus N, Mirjany M, Yemul S, Pasinetti GM. Gene expression profiling of the tau mutant (P301L) transgenic mouse brain. Neuroscience Letters. 310: 1-4. PMID 11524143 DOI: 10.1016/S0304-3940(01)02044-4  1
2001 Pasinetti GM. Cyclooxygenase and Alzheimer's disease: implications for preventive initiatives to slow the progression of clinical dementia. Archives of Gerontology and Geriatrics. 33: 13-28. PMID 11461718 DOI: 10.1016/S0167-4943(01)00091-7  1
2001 Mukherjee P, Rachita C, Aisen PS, Pasinetti GM. Non-steroidal anti-inflammatory drugs protect against chondrocyte apoptotic death. Clinical and Experimental Rheumatology. 19: S7-11. PMID 11296547  1
2001 Mukherjee P, Pasinetti GM. Complement anaphylatoxin C5a neuroprotects through mitogen-activated protein kinase-dependent inhibition of caspase 3. Journal of Neurochemistry. 77: 43-9. PMID 11279260 DOI: 10.1046/j.1471-4159.2001.00167.x  1
2001 Ho L, Purohit D, Haroutunian V, Luterman JD, Willis F, Naslund J, Buxbaum JD, Mohs RC, Aisen PS, Pasinetti GM. Neuronal cyclooxygenase 2 expression in the hippocampal formation as a function of the clinical progression of Alzheimer disease. Archives of Neurology. 58: 487-92. PMID 11255454  1
2001 Ho L, Guo Y, Spielman L, Petrescu O, Haroutunian V, Purohit D, Czernik A, Yemul S, Aisen PS, Mohs R, Pasinetti GM. Altered expression of a-type but not b-type synapsin isoform in the brain of patients at high risk for Alzheimer's disease assessed by DNA microarray technique. Neuroscience Letters. 298: 191-4. PMID 11165439 DOI: 10.1016/S0304-3940(00)01753-5  1
2000 Hull M, Pasinetti GM, Aisen PS. Elevated plasma neopterin levels in Alzheimer disease. Alzheimer Disease and Associated Disorders. 14: 228-30. PMID 11186601 DOI: 10.1097/00002093-200010000-00007  1
2000 Luterman JD, Haroutunian V, Yemul S, Ho L, Purohit D, Aisen PS, Mohs R, Pasinetti GM. Cytokine gene expression as a function of the clinical progression of Alzheimer disease dementia. Archives of Neurology. 57: 1153-60. PMID 10927795  1
2000 Ho L, Luterman JD, Aisen PS, Pasinetti GM, Montine TJ, Morrow JD. Elevated CSF prostaglandin E2 levels in patients with probable AD. Neurology. 55: 323. PMID 10908926  1
2000 Mukherjee P, Pasinetti GM. The role of complement anaphylatoxin C5a in neurodegeneration: implications in Alzheimer's disease. Journal of Neuroimmunology. 105: 124-30. PMID 10742554 DOI: 10.1016/S0165-5728(99)00261-1  1
1999 Battaini F, Pascale A, Lucchi L, Pasinetti GM, Govoni S. Protein kinase C anchoring deficit in postmortem brains of Alzheimer's disease patients. Experimental Neurology. 159: 559-64. PMID 10506528 DOI: 10.1006/exnr.1999.7151  1
1999 Kelley KA, Ho L, Winger D, Freire-Moar J, Borelli CB, Aisen PS, Pasinetti GM. Potentiation of excitotoxicity in transgenic mice overexpressing neuronal cyclooxygenase-2. The American Journal of Pathology. 155: 995-1004. PMID 10487857 DOI: 10.1016/S0002-9440(10)65199-1  1
1999 Ho L, Pieroni C, Winger D, Purohit DP, Aisen PS, Pasinetti GM. Regional distribution of cyclooxygenase-2 in the hippocampal formation in Alzheimer's disease. Journal of Neuroscience Research. 57: 295-303. PMID 10412020 DOI: 10.1002/(SICI)1097-4547(19990801)57:3<295::AID-JNR1>3.0.CO;2-0  1
1999 Osaka H, McGinty A, Höepken UE, Lu B, Gerard C, Pasinetti GM. Expression of C5a receptor in mouse brain: role in signal transduction and neurodegeneration. Neuroscience. 88: 1073-82. PMID 10336122 DOI: 10.1016/S0306-4522(98)00372-8  1
1999 Osaka H, Mukherjee P, Aisen PS, Pasinetti GM. Complement-derived anaphylatoxin C5a protects against glutamate-mediated neurotoxicity. Journal of Cellular Biochemistry. 73: 303-11. PMID 10321830 DOI: 10.1002/(SICI)1097-4644(19990601)73:3<303::AID-JCB2>3.0.CO;2-2  1
1999 Chun JT, Wang L, Pasinetti GM, Finch CE, Zlokovic BV. Glycoprotein 330/megalin (LRP-2) has low prevalence as mRNA and protein in brain microvessels and choroid plexus. Experimental Neurology. 157: 194-201. PMID 10222122 DOI: 10.1006/exnr.1999.7052  1
1999 Pasinetti GM, Hassler M, Stone D, Finch CE. Glial gene expression during aging in rat striatum and in long-term responses to 6-OHDA lesions. Synapse (New York, N.Y.). 31: 278-84. PMID 10051108 DOI: 10.1002/(SICI)1098-2396(19990315)31:4<278::AID-SYN5>3.0.CO;2-0  1
1998 Aisen PS, Luddy A, Durner M, Reinhard JF, Pasinetti GM. HLA-DR4 influences glial activity in Alzheimer's disease hippocampus. Journal of the Neurological Sciences. 161: 66-9. PMID 9879683 DOI: 10.1016/S0022-510X(98)00268-8  1
1998 Pasinetti GM. Cyclooxygenase and inflammation in Alzheimer's disease: experimental approaches and clinical interventions. Journal of Neuroscience Research. 54: 1-6. PMID 9778144 DOI: 10.1002/(SICI)1097-4547(19981001)54:1<1::AID-JNR1>3.0.CO;2-M  1
1998 Pasinetti GM, Aisen PS. Cyclooxygenase-2 expression is increased in frontal cortex of Alzheimer's disease brain. Neuroscience. 87: 319-24. PMID 9740394 DOI: 10.1016/S0306-4522(98)00218-8  1
1998 Ho L, Osaka H, Aisen PS, Pasinetti GM. Induction of cyclooxygenase (COX)-2 but not COX-1 gene expression in apoptotic cell death. Journal of Neuroimmunology. 89: 142-9. PMID 9726836 DOI: 10.1016/S0165-5728(98)00132-5  1
1998 Aisen PS, Pasinetti GM. Glucocorticoids in Alzheimer's disease. The story so far. Drugs & Aging. 12: 1-6. PMID 9467682 DOI: 10.2165/00002512-199812010-00001  1
1998 Scriabine A, Peters A, Cotman CW, Griffin WST, Pasinetti GM, Rothstein JD, Goldberg MP. Glial cells in aging and neurodegeneration. A satellite symposium to the 28(th) annual meeting of the society for neuroscience. Los Angeles, CA, November 7, 1998 Cns Drug Reviews. 4: 384-385.  1
1997 Tocco G, Musleh W, Sakhi S, Schreiber SS, Baudry M, Pasinetti GM. Complement and glutamate neurotoxicity. Genotypic influences of C5 in a mouse model of hippocampal neurodegeneration. Molecular and Chemical Neuropathology / Sponsored by the International Society For Neurochemistry and the World Federation of Neurology and Research Groups On Neurochemistry and Cerebrospinal Fluid. 31: 289-300. PMID 9336770  1
1997 Tocco G, Freire-Moar J, Schreiber SS, Sakhi SH, Aisen PS, Pasinetti GM. Maturational regulation and regional induction of cyclooxygenase-2 in rat brain: implications for Alzheimer's disease. Experimental Neurology. 144: 339-49. PMID 9168834 DOI: 10.1006/exnr.1997.6429  1
1996 Pasinetti GM, Tocco G, Sakhi S, Musleh WD, DeSimoni MG, Mascarucci P, Schreiber S, Baudry M, Finch CE. Hereditary deficiencies in complement C5 are associated with intensified neurodegenerative responses that implicate new roles for the C-system in neuronal and astrocytic functions. Neurobiology of Disease. 3: 197-204. PMID 8980020 DOI: 10.1006/nbdi.1996.0020  1
1996 Pasinetti GM. Inflammatory mechanisms in neurodegeneration and Alzheimer's disease: the role of the complement system. Neurobiology of Aging. 17: 707-16. PMID 8892343 DOI: 10.1016/0197-4580(96)00113-3  1
1996 Fratelli M, Galli G, Minto M, Pasinetti GM. Role of clusterin in cell adhesion during early phases of programmed cell death in P19 embryonic carcinoma cells. Biochimica Et Biophysica Acta. 1311: 71-6. PMID 8630332  1
1995 Bertrand P, Poirier J, Oda T, Finch CE, Pasinetti GM. Association of apolipoprotein E genotype with brain levels of apolipoprotein E and apolipoprotein J (clusterin) in Alzheimer disease. Brain Research. Molecular Brain Research. 33: 174-8. PMID 8774959 DOI: 10.1016/0169-328X(95)00097-C  1
1995 Morgan TE, Laping NJ, Rozovsky I, Oda T, Hogan TH, Finch CE, Pasinetti GM. Clusterin expression by astrocytes is influenced by transforming growth factor beta 1 and heterotypic cell interactions. Journal of Neuroimmunology. 58: 101-10. PMID 7730444 DOI: 10.1016/0165-5728(94)00194-S  1
1995 Oda T, Wals P, Osterburg HH, Johnson SA, Pasinetti GM, Morgan TE, Rozovsky I, Stine WB, Snyder SW, Holzman TF. Clusterin (apoJ) alters the aggregation of amyloid beta-peptide (A beta 1-42) and forms slowly sedimenting A beta complexes that cause oxidative stress. Experimental Neurology. 136: 22-31. PMID 7589331 DOI: 10.1006/exnr.1995.1080  1
1994 Pasinetti GM, Johnson SA, Oda T, Rozovsky I, Finch CE. Clusterin (SGP-2): a multifunctional glycoprotein with regional expression in astrocytes and neurons of the adult rat brain. The Journal of Comparative Neurology. 339: 387-400. PMID 8132868 DOI: 10.1002/cne.903390307  1
1994 Oda T, Pasinetti GM, Osterburg HH, Anderson C, Johnson SA, Finch CE. Purification and characterization of brain clusterin. Biochemical and Biophysical Research Communications. 204: 1131-6. PMID 7980587 DOI: 10.1006/bbrc.1994.2580  1
1994 Johnson SA, Pasinetti GM, Finch CE. Expression of complement C1qB and C4 mRNAs during rat brain development. Brain Research. Developmental Brain Research. 80: 163-74. PMID 7955342 DOI: 10.1016/0165-3806(94)90101-5  1
1994 Rozovsky I, Morgan TE, Willoughby DA, Dugichi-Djordjevich MM, Pasinetti GM, Johnson SA, Finch CE. Selective expression of clusterin (SGP-2) and complement C1qB and C4 during responses to neurotoxins in vivo and in vitro. Neuroscience. 62: 741-58. PMID 7870303 DOI: 10.1016/0306-4522(94)90473-1  1
1993 Morgan TE, Nichols NR, Pasinetti GM, Finch CE. TGF-beta 1 mRNA increases in macrophage/microglial cells of the hippocampus in response to deafferentation and kainic acid-induced neurodegeneration. Experimental Neurology. 120: 291-301. PMID 8491285 DOI: 10.1006/exnr.1993.1063  1
1993 Finch CE, Laping NJ, Morgan TE, Nichols NR, Pasinetti GM. TGF-beta 1 is an organizer of responses to neurodegeneration. Journal of Cellular Biochemistry. 53: 314-22. PMID 8300749 DOI: 10.1002/jcb.240530408  1
1992 Finch CE, Kohama SG, Pasinetti GM. Ovarian steroid and neurotoxin models of brain aging in rodents. Annals of the New York Academy of Sciences. 648: 119-24. PMID 1637041  1
1992 Popa-Wagner A, Day JR, Platt D, Pasinetti GM. Decortication and striatal mRNA: increases of mRNA for fibronectin, but not of NCAM or alpha-1 tubulin. Neuroreport. 3: 853-6. PMID 1421087  1
1991 Pasinetti GM, Cheng HW, Reinhard JF, Finch CE, McNeill TH. Molecular and morphological correlates following neuronal deafferentation: a cortico-striatal model. Advances in Experimental Medicine and Biology. 296: 249-55. PMID 1781331  1
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