Ohannes K. Melemedjian, Ph.D. - Publications

Affiliations: 
Pharmacology University of Arizona, Tucson, AZ 
Area:
Pain Neuroscience

29 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2017 Moy JK, Khoutorsky A, Asiedu MN, Black BJ, Kuhn JL, Barragán-Iglesias P, Megat S, Burton MD, Burgos-Vega CC, Melemedjian OK, Boitano S, Vagner J, Gkogkas CG, Pancrazio JJ, Mogil JS, et al. The MNK - eIF4E signaling axis contributes to injury-induced nociceptive plasticity and the development of chronic pain. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 28674170 DOI: 10.1523/JNEUROSCI.0220-17.2017  0.88
2016 Auh QS, Chun YH, Melemedjian OK, Zhang Y, Ro JY. Peripheral interactions between cannabinoid and opioid receptor agonists in a model of inflammatory mechanical hyperalgesia. Brain Research Bulletin. PMID 27450703 DOI: 10.1016/j.brainresbull.2016.07.009  0.88
2015 François-Moutal L, Wang Y, Moutal A, Cottier KE, Melemedjian OK, Yang X, Wang Y, Ju W, Largent-Milnes TM, Khanna M, Vanderah TW, Khanna R. A membrane-delimited N-myristoylated CRMP2 peptide aptamer inhibits CaV2.2 trafficking and reverses inflammatory and postoperative pain behaviors. Pain. 156: 1247-64. PMID 25782368 DOI: 10.1097/j.pain.0000000000000147  0.88
2015 Melemedjian OK, Khoutorsky A. Translational control of chronic pain. Progress in Molecular Biology and Translational Science. 131: 185-213. PMID 25744674 DOI: 10.1016/bs.pmbts.2014.11.006  0.88
2015 Wei X, Yan J, Tillu D, Asiedu M, Weinstein N, Melemedjian O, Price T, Dussor G. Meningeal norepinephrine produces headache behaviors in rats via actions both on dural afferents and fibroblasts. Cephalalgia : An International Journal of Headache. PMID 25601915 DOI: 10.1177/0333102414566861  0.88
2014 Wilson SM, Moutal A, Melemedjian OK, Wang Y, Ju W, François-Moutal L, Khanna M, Khanna R. The functionalized amino acid (S)-Lacosamide subverts CRMP2-mediated tubulin polymerization to prevent constitutive and activity-dependent increase in neurite outgrowth. Frontiers in Cellular Neuroscience. 8: 196. PMID 25104922 DOI: 10.3389/fncel.2014.00196  0.88
2014 Melemedjian OK, Tillu DV, Moy JK, Asiedu MN, Mandell EK, Ghosh S, Dussor G, Price TJ. Local translation and retrograde axonal transport of CREB regulates IL-6-induced nociceptive plasticity. Molecular Pain. 10: 45. PMID 24993495 DOI: 10.1186/1744-8069-10-45  0.88
2014 Wei X, Melemedjian OK, Ahn DD, Weinstein N, Dussor G. Dural fibroblasts play a potential role in headache pathophysiology. Pain. 155: 1238-44. PMID 24657451 DOI: 10.1016/j.pain.2014.03.013  0.88
2014 Melemedjian OK, Mejia GL, Lepow TS, Zoph OK, Price TJ. Bidirectional regulation of P body formation mediated by eIF4F complex formation in sensory neurons. Neuroscience Letters. 563: 169-74. PMID 24080374 DOI: 10.1016/j.neulet.2013.09.048  0.88
2013 Almawi WY, Al-Shaikh FS, Melemedjian OK, Almawi AW. Protein Z, an anticoagulant protein with expanding role in reproductive biology. Reproduction (Cambridge, England). 146: R73-80. PMID 23690629 DOI: 10.1530/REP-13-0072  0.88
2013 Melemedjian OK, Khoutorsky A, Sorge RE, Yan J, Asiedu MN, Valdez A, Ghosh S, Dussor G, Mogil JS, Sonenberg N, Price TJ. mTORC1 inhibition induces pain via IRS-1-dependent feedback activation of ERK. Pain. 154: 1080-91. PMID 23607966 DOI: 10.1016/j.pain.2013.03.021  0.88
2013 Melemedjian OK, Yassine HN, Shy A, Price TJ. Proteomic and functional annotation analysis of injured peripheral nerves reveals ApoE as a protein upregulated by injury that is modulated by metformin treatment. Molecular Pain. 9: 14. PMID 23531341 DOI: 10.1186/1744-8069-9-14  0.88
2013 Melemedjian OK, Tillu DV, Asiedu MN, Mandell EK, Moy JK, Blute VM, Taylor CJ, Ghosh S, Price TJ. BDNF regulates atypical PKC at spinal synapses to initiate and maintain a centralized chronic pain state. Molecular Pain. 9: 12. PMID 23510079 DOI: 10.1186/1744-8069-9-12  0.88
2012 King T, Qu C, Okun A, Melemedjian OK, Mandell EK, Maskaykina IY, Navratilova E, Dussor GO, Ghosh S, Price TJ, Porreca F. Contribution of PKMζ-dependent and independent amplification to components of experimental neuropathic pain. Pain. 153: 1263-73. PMID 22482911 DOI: 10.1016/j.pain.2012.03.006  0.88
2012 Yan J, Melemedjian OK, Price TJ, Dussor G. Sensitization of dural afferents underlies migraine-related behavior following meningeal application of interleukin-6 (IL-6). Molecular Pain. 8: 6. PMID 22273495 DOI: 10.1186/1744-8069-8-6  0.88
2012 Tillu DV, Melemedjian OK, Asiedu MN, Qu N, De Felice M, Dussor G, Price TJ. Resveratrol engages AMPK to attenuate ERK and mTOR signaling in sensory neurons and inhibits incision-induced acute and chronic pain. Molecular Pain. 8: 5. PMID 22269797 DOI: 10.1186/1744-8069-8-5  0.88
2012 Melemedjian OK, Price TJ. Dendritic spine plasticity as an underlying mechanism of neuropathic pain: commentary on Tan et al. Experimental Neurology. 233: 740-4. PMID 22119623 DOI: 10.1016/j.expneurol.2011.11.016  0.88
2012 Price TJ, Melemedjian OK. Fragile X mental retardation protein (FMRP) and the spinal sensory system. Results and Problems in Cell Differentiation. 54: 41-59. PMID 22009347 DOI: 10.1007/978-3-642-21649-7_4  0.88
2011 Melemedjian OK, Asiedu MN, Tillu DV, Sanoja R, Yan J, Lark A, Khoutorsky A, Johnson J, Peebles KA, Lepow T, Sonenberg N, Dussor G, Price TJ. Targeting adenosine monophosphate-activated protein kinase (AMPK) in preclinical models reveals a potential mechanism for the treatment of neuropathic pain. Molecular Pain. 7: 70. PMID 21936900 DOI: 10.1186/1744-8069-7-70  0.88
2011 Asiedu MN, Tillu DV, Melemedjian OK, Shy A, Sanoja R, Bodell B, Ghosh S, Porreca F, Price TJ. Spinal protein kinase M ζ underlies the maintenance mechanism of persistent nociceptive sensitization. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 6646-53. PMID 21543593 DOI: 10.1523/JNEUROSCI.6286-10.2011  0.88
2010 Melemedjian OK, Asiedu MN, Tillu DV, Peebles KA, Yan J, Ertz N, Dussor GO, Price TJ. IL-6- and NGF-induced rapid control of protein synthesis and nociceptive plasticity via convergent signaling to the eIF4F complex. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 15113-23. PMID 21068317 DOI: 10.1523/JNEUROSCI.3947-10.2010  0.88
2010 Vardanyan M, Melemedjian OK, Price TJ, Ossipov MH, Lai J, Roberts E, Boos TL, Deschamps JR, Jacobson AE, Rice KC, Porreca F. Reversal of pancreatitis-induced pain by an orally available, small molecule interleukin-6 receptor antagonist. Pain. 151: 257-65. PMID 20599324 DOI: 10.1016/j.pain.2010.05.022  0.88
2008 Jimenez-Andrade JM, Herrera MB, Ghilardi JR, Vardanyan M, Melemedjian OK, Mantyh PW. Vascularization of the dorsal root ganglia and peripheral nerve of the mouse: implications for chemical-induced peripheral sensory neuropathies. Molecular Pain. 4: 10. PMID 18353190 DOI: 10.1186/1744-8069-4-10  0.88
2007 King T, Vardanyan A, Majuta L, Melemedjian O, Nagle R, Cress AE, Vanderah TW, Lai J, Porreca F. Morphine treatment accelerates sarcoma-induced bone pain, bone loss, and spontaneous fracture in a murine model of bone cancer. Pain. 132: 154-68. PMID 17706870 DOI: 10.1016/j.pain.2007.06.026  0.88
2004 Almawi WY, Melemedjian OK, Jaoude MM. On the link between Bcl-2 family proteins and glucocorticoid-induced apoptosis. Journal of Leukocyte Biology. 76: 7-14. PMID 15075361 DOI: 10.1189/jlb.0903450  0.88
2002 Almawi WY, Melemedjian OK. Negative regulation of nuclear factor-kappaB activation and function by glucocorticoids. Journal of Molecular Endocrinology. 28: 69-78. PMID 11932204 DOI: 10.1677/jme.0.0280069  0.88
2002 Almawi WY, Melemedjian OK. Molecular mechanisms of glucocorticoid antiproliferative effects: antagonism of transcription factor activity by glucocorticoid receptor. Journal of Leukocyte Biology. 71: 9-15. PMID 11781376  0.88
2000 Almawi WY, Melemedjian OK. Clinical and mechanistic differences between FK506 (tacrolimus) and cyclosporin A. Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association. 15: 1916-8. PMID 11096132  0.88
1999 Almawi WY, Melemedjian OK, Rieder MJ. An alternate mechanism of glucocorticoid anti-proliferative effect: promotion of a Th2 cytokine-secreting profile. Clinical Transplantation. 13: 365-74. PMID 10515216 DOI: 10.1034/j.1399-0012.1999.130501.x  0.88
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