| Year |
Citation |
Score |
| 2020 |
Ullman JC, Arguello A, Getz JA, Bhalla A, Mahon CS, Wang J, Giese T, Bedard C, Kim DJ, Blumenfeld JR, Liang N, Ravi R, Nugent AA, Davis SS, Ha C, ... ... Diaz D, et al. Brain delivery and activity of a lysosomal enzyme using a blood-brain barrier transport vehicle in mice. Science Translational Medicine. 12. PMID 32461331 DOI: 10.1126/Scitranslmed.Aay1163 |
0.372 |
|
| 2016 |
Diaz D, Pai R, Cain G, La N, Dambach D, Schwartz J, Tarrant JM. MEK and ERK Kinase Inhibitors Increase Circulating Ceruloplasmin and Cause Green Serum in Rats. Toxicologic Pathology. PMID 27565173 DOI: 10.1177/0192623316664590 |
0.325 |
|
| 2016 |
Rudolph J, Murray LJ, Ndubaku CO, O'Brien T, Blackwood EM, Wang W, Aliagas I, Gazzard L, Crawford JJ, Drobnick J, Lee W, Zhao X, Hoeflich KP, Favor DA, Dong P, ... ... Diaz D, et al. Chemically diverse Group I p21-activated kinase (PAK) inhibitors impart acute cardiovascular toxicity with a narrow therapeutic window. Journal of Medicinal Chemistry. PMID 27167326 DOI: 10.1021/Acs.Jmedchem.6B00638 |
0.313 |
|
| 2016 |
Lee DU, Katavolos P, Palanisamy G, Katewa A, Sioson C, Corpuz J, Pang J, DeMent K, Choo E, Ghilardi N, Diaz D, Danilenko DM. Nonselective inhibition of the epigenetic transcriptional regulator BET induces marked lymphoid and hematopoietic toxicity in mice. Toxicology and Applied Pharmacology. 300: 47-54. PMID 27078884 DOI: 10.1016/J.Taap.2016.03.013 |
0.357 |
|
| 2015 |
Zhong Y, Katavolos P, Nguyen T, Lau T, Boggs J, Sambrone A, Kan D, Merchant M, Harstad E, Diaz D, Costa M, Schutten M. Tankyrase Inhibition Causes Reversible Intestinal Toxicity in Mice with a Therapeutic Index < 1. Toxicologic Pathology. PMID 26692561 DOI: 10.1177/0192623315621192 |
0.329 |
|
| 2015 |
Dambach DM, Misner D, Brock M, Fullerton A, Proctor W, Maher J, Lee D, Ford KA, Diaz D. Safety Lead Optimization and Candidate Identification: Integrating New Technologies into Decision-Making. Chemical Research in Toxicology. PMID 26625186 DOI: 10.1021/Acs.Chemrestox.5B00396 |
0.303 |
|
| 2015 |
Ford KA, Ryslik G, Sodhi J, Halladay J, Diaz D, Dambach D, Masuda M. Computational predictions of the site of metabolism of cytochrome P450 2D6 substrates: comparative analysis, molecular docking, bioactivation and toxicological implications. Drug Metabolism Reviews. 1-29. PMID 26024250 DOI: 10.3109/03602532.2015.1047026 |
0.32 |
|
| 2015 |
Tarrant JM, Dhawan P, Singh J, Zabka TS, Clarke E, DosSantos G, Dragovich PS, Sampath D, Lin T, McCray B, La N, Nguyen T, Kauss A, Dambach D, Misner DL, ... Diaz D, et al. Preclinical models of nicotinamide phosphoribosyltransferase inhibitor-mediated hematotoxicity and mitigation by co-treatment with nicotinic acid. Toxicology Mechanisms and Methods. 25: 201-11. PMID 25894564 DOI: 10.3109/15376516.2015.1014080 |
0.358 |
|
| 2013 |
Poulin P, Dambach DM, Hartley DH, Ford K, Theil FP, Harstad E, Halladay J, Choo E, Boggs J, Liederer BM, Dean B, Diaz D. An algorithm for evaluating potential tissue drug distribution in toxicology studies from readily available pharmacokinetic parameters. Journal of Pharmaceutical Sciences. 102: 3816-29. PMID 23878104 DOI: 10.1002/Jps.23670 |
0.337 |
|
| 2013 |
Diaz D, Ford KA, Hartley DP, Harstad EB, Cain GR, Achilles-Poon K, Nguyen T, Peng J, Zheng Z, Merchant M, Sutherlin DP, Gaudino JJ, Kaus R, Lewin-Koh SC, Choo EF, et al. Pharmacokinetic drivers of toxicity for basic molecules: strategy to lower pKa results in decreased tissue exposure and toxicity for a small molecule Met inhibitor. Toxicology and Applied Pharmacology. 266: 86-94. PMID 23142475 DOI: 10.1016/J.Taap.2012.10.026 |
0.367 |
|
| 2013 |
Erickson RI, Tarrant J, Cain G, Lewin-Koh SC, Dybdal N, Wong H, Blackwood E, West K, Steigerwalt R, Mamounas M, Flygare JA, Amemiya K, Dambach D, Fairbrother WJ, Diaz D. Toxicity profile of small-molecule IAP antagonist GDC-0152 is linked to TNF-α pharmacology. Toxicological Sciences : An Official Journal of the Society of Toxicology. 131: 247-58. PMID 22956632 DOI: 10.1093/Toxsci/Kfs265 |
0.329 |
|
| 2012 |
Diaz D, Allamneni K, Tarrant JM, Lewin-Koh SC, Pai R, Dhawan P, Cain GR, Kozlowski C, Hiraragi H, La N, Hartley DP, Ding X, Dean BJ, Bheddah S, Dambach DM. Phosphorous dysregulation induced by MEK small molecule inhibitors in the rat involves blockade of FGF-23 signaling in the kidney. Toxicological Sciences : An Official Journal of the Society of Toxicology. 125: 187-95. PMID 21976371 DOI: 10.1093/Toxsci/Kfr263 |
0.315 |
|
| 2007 |
Diaz D, Scott A, Carmichael P, Shi W, Costales C. Evaluation of an automated in vitro micronucleus assay in CHO-K1 cells. Mutation Research. 630: 1-13. PMID 17446119 DOI: 10.1016/J.Mrgentox.2007.02.006 |
0.306 |
|
| 2006 |
O'Brien PJ, Irwin W, Diaz D, Howard-Cofield E, Krejsa CM, Slaughter MR, Gao B, Kaludercic N, Angeline A, Bernardi P, Brain P, Hougham C. High concordance of drug-induced human hepatotoxicity with in vitro cytotoxicity measured in a novel cell-based model using high content screening. Archives of Toxicology. 80: 580-604. PMID 16598496 DOI: 10.1007/S00204-006-0091-3 |
0.641 |
|
| 2004 |
Xu JJ, Diaz D, O'Brien PJ. Applications of cytotoxicity assays and pre-lethal mechanistic assays for assessment of human hepatotoxicity potential. Chemico-Biological Interactions. 150: 115-28. PMID 15522265 DOI: 10.1016/J.Cbi.2004.09.011 |
0.345 |
|
| 2004 |
Díaz D, Krejsa CM, White CC, Charleston JS, Kavanagh TJ. Effect of methylmercury on glutamate-cysteine ligase expression in the placenta and yolk sac during mouse development. Reproductive Toxicology (Elmsford, N.Y.). 19: 117-29. PMID 15336720 DOI: 10.1016/J.Reprotox.2004.06.006 |
0.701 |
|
| 2003 |
Luderer U, Diaz D, Faustman EM, Kavanagh TJ. Localization of glutamate cysteine ligase subunit mRNA within the rat ovary and relationship to follicular apoptosis. Molecular Reproduction and Development. 65: 254-61. PMID 12784246 DOI: 10.1002/Mrd.10298 |
0.597 |
|
| 2002 |
Díaz D, Krejsa CM, Kavanagh TJ. Expression of glutamate-cysteine ligase during mouse development. Molecular Reproduction and Development. 62: 83-91. PMID 11933164 DOI: 10.1002/Mrd.10076 |
0.693 |
|
| 1999 |
Kirlin WG, Cai J, Thompson SA, Diaz D, Kavanagh TJ, Jones DP. Glutathione redox potential in response to differentiation and enzyme inducers. Free Radical Biology & Medicine. 27: 1208-18. PMID 10641713 DOI: 10.1016/S0891-5849(99)00145-8 |
0.582 |
|
| 1999 |
Thompson SA, White CC, Krejsa CM, Diaz D, Woods JS, Eaton DL, Kavanagh TJ. Induction of glutamate-cysteine ligase (gamma-glutamylcysteine synthetase) in the brains of adult female mice subchronically exposed to methylmercury. Toxicology Letters. 110: 1-9. PMID 10593589 DOI: 10.1016/S0378-4274(99)00133-2 |
0.684 |
|
| 1999 |
Woods JS, Kavanagh TJ, Corral J, Reese AW, Diaz D, Ellis ME. The role of glutathione in chronic adaptation to oxidative stress: studies in a normal rat kidney epithelial (NRK52E) cell model of sustained upregulation of glutathione biosynthesis. Toxicology and Applied Pharmacology. 160: 207-16. PMID 10544055 DOI: 10.1006/Taap.1999.8774 |
0.577 |
|
| 1999 |
Nelson KC, Carlson JL, Newman ML, Sternberg P, Jones DP, Kavanagh TJ, Diaz D, Cai J, Wu M. Effect of dietary inducer dimethylfumarate on glutathione in cultured human retinal pigment epithelial cells. Investigative Ophthalmology & Visual Science. 40: 1927-35. PMID 10440245 |
0.492 |
|
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