Jialin C. Zheng, M.D. - Publications

Affiliations: 
Pharmacology & Experimental Neuroscience University of Nebraska Medical Center, Omaha, NE, United States 
Area:
neurotoxicology, neural stem cells
Website:
http://www.unmc.edu/pharmacology/zheng.htm

110 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Chen X, Guo J, Huang Y, Liu S, Huang Y, Zhang Z, Zhang F, Lu Z, Li F, Zheng JC, Ding W. Urban airborne PM-activated microglia mediate neurotoxicity through glutaminase-containing extracellular vesicles in olfactory bulb. Environmental Pollution (Barking, Essex : 1987). 264: 114716. PMID 32559876 DOI: 10.1016/J.Envpol.2020.114716  0.65
2020 Gao G, Li C, Zhu J, Wang Y, Huang Y, Zhao S, Sheng S, Song Y, Ji C, Li C, Yang X, Ye L, Qi X, Zhang Y, Xia X, ... Zheng JC, et al. Glutaminase 1 Regulates Neuroinflammation After Cerebral Ischemia Through Enhancing Microglial Activation and Pro-Inflammatory Exosome Release. Frontiers in Immunology. 11: 161. PMID 32117296 DOI: 10.3389/Fimmu.2020.00161  0.701
2020 Xia X, Li C, Wang Y, Deng X, Ma Y, Ding L, Zheng J. Reprogrammed astrocytes display higher neurogenic competence, migration ability and cell death resistance than reprogrammed fibroblasts. Translational Neurodegeneration. 9: 6. PMID 32071715 DOI: 10.1186/S40035-020-0184-6  0.358
2019 Xia X, Lu H, Li C, Huang Y, Wang Y, Yang X, Zheng JC. miR-106b regulates the proliferation and differentiation of neural stem/progenitor cells through Tp53inp1-Tp53-Cdkn1a axis. Stem Cell Research & Therapy. 10: 282. PMID 31547867 DOI: 10.1186/S13287-019-1387-6  0.594
2019 Xia X, Wang Y, Huang Y, Zhang H, Lu H, Zheng JC. Exosomal MiRNAs in Central Nervous System Diseases: Biomarkers, Pathological Mediators, Protective Factors and Therapeutic Agents. Progress in Neurobiology. 101694. PMID 31542363 DOI: 10.1016/J.Pneurobio.2019.101694  0.617
2019 Ma Y, Li C, Huang Y, Wang Y, Xia X, Zheng JC. Exosomes released from neural progenitor cells and induced neural progenitor cells regulate neurogenesis through miR-21a. Cell Communication and Signaling : Ccs. 17: 96. PMID 31419975 DOI: 10.1186/S12964-019-0418-3  0.637
2019 Gao G, Zhao S, Xia X, Li C, Li C, Ji C, Sheng S, Tang Y, Zhu J, Wang Y, Huang Y, Zheng JC. Glutaminase C Regulates Microglial Activation and Pro-inflammatory Exosome Release: Relevance to the Pathogenesis of Alzheimer's Disease. Frontiers in Cellular Neuroscience. 13: 264. PMID 31316350 DOI: 10.3389/fncel.2019.00264  0.673
2019 Zhao R, Li Y, Gorantla S, Poluektova LY, Lin H, Gao F, Wang H, Zhao J, Zheng JC, Huang Y. Small molecule ONC201 inhibits HIV-1 replication in macrophages via FOXO3a and TRAIL. Antiviral Research. PMID 31158413 DOI: 10.1016/J.Antiviral.2019.05.015  0.754
2019 Liu J, Li Y, Xia X, Yang X, Zhao R, Peer J, Wang H, Tong Z, Gao F, Lin H, Wu B, Huang Y, Zheng JC. Journal of Neuroimmunology. 333: 476962. PMID 31108401 DOI: 10.1016/J.Jneuroim.2019.05.003  0.674
2019 He M, Zhang H, Li Y, Tian C, Tang B, Huang Y, Zheng J. Direct and selective lineage conversion of human fibroblasts to dopaminergic precursors. Neuroscience Letters. PMID 30664902 DOI: 10.1016/J.Neulet.2019.01.033  0.654
2018 Ma Y, Wang K, Pan J, Fan Z, Tian C, Deng X, Ma K, Xia X, Huang Y, Zheng JC. Induced neural progenitor cells abundantly secrete extracellular vesicles and promote the proliferation of neural progenitors via extracellular signal-regulated kinase pathways. Neurobiology of Disease. PMID 30528256 DOI: 10.1016/J.Nbd.2018.12.003  0.738
2018 Ma K, Deng X, Xia X, Fan Z, Qi X, Wang Y, Li Y, Ma Y, Chen Q, Peng H, Ding J, Li C, Huang Y, Tian C, Zheng JC. Direct conversion of mouse astrocytes into neural progenitor cells and specific lineages of neurons. Translational Neurodegeneration. 7: 29. PMID 30410751 DOI: 10.1186/S40035-018-0132-X  0.727
2018 Huang Y, Li Y, Zhang H, Zhao R, Jing R, Xu Y, He M, Peer J, Kim YC, Luo J, Tong Z, Zheng J. Zika virus propagation and release in human fetal astrocytes can be suppressed by neutral sphingomyelinase-2 inhibitor GW4869. Cell Discovery. 4: 19. PMID 29707233 DOI: 10.1038/S41421-018-0017-2  0.706
2018 He M, Zhang H, Li Y, Wang G, Tang B, Zhao J, Huang Y, Zheng J. Cathelicidin-Derived Antimicrobial Peptides Inhibit Zika Virus Through Direct Inactivation and Interferon Pathway. Frontiers in Immunology. 9: 722. PMID 29706959 DOI: 10.3389/Fimmu.2018.00722  0.668
2018 Wu B, Liu J, Zhao R, Li Y, Peer J, Braun AL, Zhao L, Wang Y, Tong Z, Huang Y, Zheng JC. Glutaminase 1 regulates the release of extracellular vesicles during neuroinflammation through key metabolic intermediate alpha-ketoglutarate. Journal of Neuroinflammation. 15: 79. PMID 29540215 DOI: 10.1186/S12974-018-1120-X  0.691
2017 Zhang M, Qiu L, Zhang Y, Xu D, Zheng JC, Jiang L. CXCL12 enhances angiogenesis through CXCR7 activation in human umbilical vein endothelial cells. Scientific Reports. 7: 8289. PMID 28811579 DOI: 10.1038/S41598-017-08840-Y  0.313
2017 Xu P, Wang Y, Qin Z, Qiu L, Zhang M, Huang Y, Zheng JC. Combined Medication of Antiretroviral Drugs Tenofovir Disoproxil Fumarate, Emtricitabine, and Raltegravir Reduces Neural Progenitor Cell Proliferation In Vivo and In Vitro. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. PMID 28735382 DOI: 10.1007/S11481-017-9755-4  0.695
2017 Wang Y, Li Y, Zhao R, Wu B, Lanoha B, Tong Z, Peer J, Liu J, Xiong H, Huang Y, Zheng J. Glutaminase C overexpression in the brain induces learning deficits, synaptic dysfunctions, and neuroinflammation in mice. Brain, Behavior, and Immunity. PMID 28624534 DOI: 10.1016/J.Bbi.2017.06.007  0.642
2017 Li Y, Peer J, Zhao R, Xu Y, Wu B, Wang Y, Tian C, Huang Y, Zheng J. Serial deletion reveals structural basis and stability for the core enzyme activity of human glutaminase 1 isoforms: relevance to excitotoxic neurodegeneration. Translational Neurodegeneration. 6: 10. PMID 28439409 DOI: 10.1186/S40035-017-0080-X  0.678
2017 Wang K, Ye L, Lu H, Chen H, Zhang Y, Huang Y, Zheng JC. TNF-α promotes extracellular vesicle release in mouse astrocytes through glutaminase. Journal of Neuroinflammation. 14: 87. PMID 28427419 DOI: 10.1186/S12974-017-0853-2  0.664
2016 Wang Y, Xu P, Qiu L, Zhang M, Huang Y, Zheng JC. CXCR7 participates in CXCL12 mediated cell cycle and proliferation regulation in mouse neural progenitor cells. Current Molecular Medicine. PMID 27573194 DOI: 10.2174/1566524016666160829153453  0.667
2016 Yang Z, Liu Y, Ahn J, Qiao Z, Endres JL, Gautam N, Huang Y, Li J, Zheng J, Alnouti Y, Bayles KW, Li R. Novel fluorinated pyrrolomycins as potent anti-staphylococcal biofilm agents: Design, synthesis, pharmacokinetics and antibacterial activities. European Journal of Medicinal Chemistry. 124: 129-137. PMID 27565555 DOI: 10.1016/J.Ejmech.2016.08.017  0.622
2016 Smith DK, He M, Zhang CL, Zheng JC. The Therapeutic Potential of Cell Identity Reprogramming for the Treatment of Aging-Related Neurodegenerative Disorders. Progress in Neurobiology. PMID 26844759 DOI: 10.1016/J.Pneurobio.2016.01.006  0.337
2015 Zhang M, Song A, Lai S, Qiu L, Huang Y, Chen Q, Zhu B, Xu D, Zheng JC. Living cell imaging and Rac1-GTP levels of CXCL12-treated migrating neural progenitor cells in stripe assay. Data in Brief. 5: 712-6. PMID 26693502 DOI: 10.1016/J.Dib.2015.09.048  0.64
2015 Wu B, Huang Y, Braun AL, Tong Z, Zhao R, Li Y, Liu F, Zheng JC. Glutaminase-containing microvesicles from HIV-1-infected macrophages and immune-activated microglia induce neurotoxicity. Molecular Neurodegeneration. 10: 61. PMID 26546362 DOI: 10.1186/S13024-015-0058-Z  0.772
2015 Zhang M, Song A, Lai S, Qiu L, Huang Y, Chen Q, Zhu B, Xu D, Zheng JC. Applications of stripe assay in the study of CXCL12-mediated neural progenitor cell migration and polarization. Biomaterials. 72: 163-171. PMID 26396061 DOI: 10.1016/J.Biomaterials.2015.08.052  0.657
2015 Tian C, Li Y, Huang Y, Wang Y, Chen D, Liu J, Deng X, Sun L, Anderson K, Qi X, Li Y, Mosley RL, Chen X, Huang J, Zheng JC. Selective Generation of Dopaminergic Precursors from Mouse Fibroblasts by Direct Lineage Conversion. Scientific Reports. 5: 12622. PMID 26224135 DOI: 10.1038/Srep12622  0.658
2015 Liu F, Huang Y, Zhang F, Chen Q, Wu B, Rui W, Zheng JC, Ding W. Macrophages treated with particulate matter PM2.5 induce selective neurotoxicity through glutaminase-mediated glutamate generation. Journal of Neurochemistry. 134: 315-26. PMID 25913161 DOI: 10.1111/Jnc.13135  0.677
2015 Chen Q, Zhang M, Li Y, Xu D, Wang Y, Song A, Zhu B, Huang Y, Zheng JC. CXCR7 Mediates Neural Progenitor Cells Migration to CXCL12 Independent of CXCR4. Stem Cells (Dayton, Ohio). PMID 25833331 DOI: 10.1002/Stem.2022  0.676
2015 Zhang M, Song A, Lai S, Qiu L, Huang Y, Chen Q, Zhu B, Xu D, Zheng JC. Living cell imaging and Rac1-GTP levels of CXCL12-treated migrating neural progenitor cells in stripe assay Data in Brief. 5: 712-716. DOI: 10.1016/j.dib.2015.09.048  0.603
2014 Wang Y, Huang Y, Zhao L, Li Y, Zheng J. Glutaminase 1 is essential for the differentiation, proliferation, and survival of human neural progenitor cells. Stem Cells and Development. 23: 2782-90. PMID 24923593 DOI: 10.1089/Scd.2014.0022  0.692
2014 Al-Harthi L, Buch S, Geiger JD, Gendelman HE, He JJ, Jordan-Sciutto KL, Kolson DL, Rappaport J, Roy S, Zheng J, Fox HS. Cellular Interactions and Signaling in neuroAIDS: Emerging Issues Colloquium. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. 9: 269-76. PMID 24789373 DOI: 10.1007/S11481-014-9545-1  0.455
2013 Zhao L, Huang Y, Zheng J. STAT1 regulates human glutaminase 1 promoter activity through multiple binding sites in HIV-1 infected macrophages. Plos One. 8: e76581. PMID 24086752 DOI: 10.1371/Journal.Pone.0076581  0.727
2013 Chen E, Xu D, Lan X, Jia B, Sun L, Zheng JC, Peng H. A novel role of the STAT3 pathway in brain inflammation-induced human neural progenitor cell differentiation. Current Molecular Medicine. 13: 1474-84. PMID 23971732 DOI: 10.2174/15665240113139990076  0.402
2013 Ye L, Zhao X, Lu J, Qian G, Zheng JC, Ge S. Knockdown of TIGAR by RNA interference induces apoptosis and autophagy in HepG2 hepatocellular carcinoma cells. Biochemical and Biophysical Research Communications. 437: 300-6. PMID 23817040 DOI: 10.1016/J.Bbrc.2013.06.072  0.31
2013 Wang Y, Tian C, Zheng JC. FoxO3a contributes to the reprogramming process and the differentiation of induced pluripotent stem cells. Stem Cells and Development. 22: 2954-63. PMID 23815557 DOI: 10.1089/Scd.2013.0044  0.34
2013 Ye L, Huang Y, Zhao L, Li Y, Sun L, Zhou Y, Qian G, Zheng JC. IL-1β and TNF-α induce neurotoxicity through glutamate production: a potential role for neuronal glutaminase. Journal of Neurochemistry. 125: 897-908. PMID 23578284 DOI: 10.1111/Jnc.12263  0.719
2013 Tian C, Liu Q, Ma K, Wang Y, Chen Q, Ambroz R, Klinkebiel DL, Li Y, Huang Y, Ding J, Wu J, Zheng JC. Characterization of induced neural progenitors from skin fibroblasts by a novel combination of defined factors. Scientific Reports. 3: 1345. PMID 23439431 DOI: 10.1038/Srep01345  0.748
2012 Lan X, Chen Q, Wang Y, Jia B, Sun L, Zheng J, Peng H, Combs C. TNF-α Affects Human Cortical Neural Progenitor Cell Differentiation through the Autocrine Secretion of Leukemia Inhibitory Factor Plos One. 7. PMID 23236394 DOI: 10.1371/Journal.Pone.0050783  0.328
2012 Wu Y, Chen Q, Peng H, Dou H, Zhou Y, Huang Y, Zheng JC. Directed migration of human neural progenitor cells to interleukin-1β is promoted by chemokines stromal cell-derived factor-1 and monocyte chemotactic factor-1 in mouse brains. Translational Neurodegeneration. 1: 15. PMID 23210607 DOI: 10.1186/2047-9158-1-15  0.715
2012 Peng H, Wu Y, Duan Z, Ciborowski P, Zheng JC. Proteolytic processing of SDF-1α by matrix metalloproteinase-2 impairs CXCR4 signaling and reduces neural progenitor cell migration. Protein & Cell. 3: 875-82. PMID 23143873 DOI: 10.1007/S13238-012-2092-8  0.476
2012 Zhu B, Xu D, Deng X, Chen Q, Huang Y, Peng H, Li Y, Jia B, Thoreson WB, Ding W, Ding J, Zhao L, Wang Y, Wavrin KL, Duan S, ... Zheng J, et al. CXCL12 enhances human neural progenitor cell survival through a CXCR7- and CXCR4-mediated endocytotic signaling pathway. Stem Cells (Dayton, Ohio). 30: 2571-83. PMID 22987307 DOI: 10.1002/Stem.1239  0.687
2012 Tian C, Sun L, Jia B, Ma K, Curthoys N, Ding J, Zheng J. Mitochondrial glutaminase release contributes to glutamate-mediated neurotoxicity during human immunodeficiency virus-1 infection. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. 7: 619-28. PMID 22527635 DOI: 10.1007/S11481-012-9364-1  0.681
2012 Zhao L, Huang Y, Tian C, Taylor L, Curthoys N, Wang Y, Vernon H, Zheng J. Interferon-α regulates glutaminase 1 promoter through STAT1 phosphorylation: relevance to HIV-1 associated neurocognitive disorders. Plos One. 7: e32995. PMID 22479354 DOI: 10.1371/Journal.Pone.0032995  0.75
2012 Tian C, Ambroz RJ, Sun L, Wang Y, Ma K, Chen Q, Zhu B, Zheng JC. Direct conversion of dermal fibroblasts into neural progenitor cells by a novel cocktail of defined factors. Current Molecular Medicine. 12: 126-37. PMID 22172100 DOI: 10.2174/156652412798889018  0.55
2012 Lan X, Kiyota T, Hanamsagar R, Huang Y, Andrews S, Peng H, Zheng JC, Swindells S, Carlson GA, Ikezu T. The effect of HIV protease inhibitors on amyloid-β peptide degradation and synthesis in human cells and Alzheimer's disease animal model. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. 7: 412-23. PMID 21826404 DOI: 10.1007/S11481-011-9304-5  0.717
2011 Huang Y, Zhao L, Jia B, Wu L, Li Y, Curthoys N, Zheng JC. Glutaminase dysregulation in HIV-1-infected human microglia mediates neurotoxicity: relevant to HIV-1-associated neurocognitive disorders. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 15195-204. PMID 22016553 DOI: 10.1523/Jneurosci.2051-11.2011  0.767
2011 Peng H, Sun L, Jia B, Lan X, Zhu B, Wu Y, Zheng J. HIV-1-infected and immune-activated macrophages induce astrocytic differentiation of human cortical neural progenitor cells via the STAT3 pathway. Plos One. 6: e19439. PMID 21637744 DOI: 10.1371/Journal.Pone.0019439  0.552
2011 Lan X, Xu J, Kiyota T, Peng H, Zheng JC, Ikezu T. HIV-1 reduces Abeta-degrading enzymatic activities in primary human mononuclear phagocytes. Journal of Immunology (Baltimore, Md. : 1950). 186: 6925-32. PMID 21551363 DOI: 10.4049/Jimmunol.1100211  0.525
2011 Tian C, Wang Y, Sun L, Ma K, Zheng JC. Reprogrammed mouse astrocytes retain a "memory" of tissue origin and possess more tendencies for neuronal differentiation than reprogrammed mouse embryonic fibroblasts. Protein & Cell. 2: 128-40. PMID 21380643 DOI: 10.1007/S13238-011-1012-7  0.555
2011 Constantino AA, Huang Y, Zhang H, Wood C, Zheng JC. HIV-1 clade B and C isolates exhibit differential replication: relevance to macrophage-mediated neurotoxicity. Neurotoxicity Research. 20: 277-88. PMID 21336667 DOI: 10.1007/S12640-011-9241-3  0.823
2011 Cui M, Huang Y, Tian C, Zhao Y, Zheng J. FOXO3a inhibits TNF-α- and IL-1β-induced astrocyte proliferation:Implication for reactive astrogliosis. Glia. 59: 641-54. PMID 21294163 DOI: 10.1002/Glia.21134  0.67
2011 Letendre SL, Zheng JC, Kaul M, Yiannoutsos CT, Ellis RJ, Taylor MJ, Marquie-Beck J, Navia B. Chemokines in cerebrospinal fluid correlate with cerebral metabolite patterns in HIV-infected individuals. Journal of Neurovirology. 17: 63-9. PMID 21246320 DOI: 10.1007/S13365-010-0013-2  0.485
2009 Cui M, Huang Y, Zhao Y, Zheng J. New insights for FOXO and cell-fate decision in HIV infection and HIV associated neurocognitive disorder. Advances in Experimental Medicine and Biology. 665: 143-59. PMID 20429422 DOI: 10.1007/978-1-4419-1599-3_11  0.758
2009 Tian C, Murrin LC, Zheng JC. Mitochondrial fragmentation is involved in methamphetamine-induced cell death in rat hippocampal neural progenitor cells. Plos One. 4: e5546. PMID 19436752 DOI: 10.1371/Journal.Pone.0005546  0.327
2009 Huang Y, Walstrom A, Zhang L, Zhao Y, Cui M, Ye L, Zheng JC. Type I interferons and interferon regulatory factors regulate TNF-related apoptosis-inducing ligand (TRAIL) in HIV-1-infected macrophages. Plos One. 4: e5397. PMID 19404407 DOI: 10.1371/Journal.Pone.0005397  0.761
2009 Wu Y, Peng H, Cui M, Whitney NP, Huang Y, Zheng JC. CXCL12 increases human neural progenitor cell proliferation through Akt-1/FOXO3a signaling pathway. Journal of Neurochemistry. 109: 1157-67. PMID 19302476 DOI: 10.1111/J.1471-4159.2009.06043.X  0.786
2009 Erdmann N, Tian C, Huang Y, Zhao J, Herek S, Curthoys N, Zheng J. In vitro glutaminase regulation and mechanisms of glutamate generation in HIV-1-infected macrophage. Journal of Neurochemistry. 109: 551-61. PMID 19222703 DOI: 10.1111/J.1471-4159.2009.05989.X  0.835
2009 Whitney NP, Eidem TM, Peng H, Huang Y, Zheng JC. Inflammation mediates varying effects in neurogenesis: relevance to the pathogenesis of brain injury and neurodegenerative disorders. Journal of Neurochemistry. 108: 1343-59. PMID 19154336 DOI: 10.1111/J.1471-4159.2009.05886.X  0.801
2008 Zheng JC, Huang Y, Tang K, Cui M, Niemann D, Lopez A, Morgello S, Chen S. HIV-1-infected and/or immune-activated macrophages regulate astrocyte CXCL8 production through IL-1beta and TNF-alpha: involvement of mitogen-activated protein kinases and protein kinase R. Journal of Neuroimmunology. 200: 100-10. PMID 18653246 DOI: 10.1016/J.Jneuroim.2008.06.015  0.721
2008 Whitney NP, Peng H, Erdmann NB, Tian C, Monaghan DT, Zheng JC. Calcium-permeable AMPA receptors containing Q/R-unedited GluR2 direct human neural progenitor cell differentiation to neurons. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 22: 2888-900. PMID 18403631 DOI: 10.1096/Fj.07-104661  0.77
2008 Peng H, Whitney N, Wu Y, Tian C, Dou H, Zhou Y, Zheng J. HIV-1-infected and/or immune-activated macrophage-secreted TNF-α affects human fetal cortical neural progenitor cell proliferation and differentiation Glia. 56: 903-916. PMID 18383342 DOI: 10.1002/Glia.20665  0.846
2008 Cui M, Huang Y, Zhao Y, Zheng J. Transcription factor FOXO3a mediates apoptosis in HIV-1-infected macrophages. Journal of Immunology (Baltimore, Md. : 1950). 180: 898-906. PMID 18178829 DOI: 10.4049/Jimmunol.180.2.898  0.762
2008 Tian C, Erdmann N, Zhao J, Cao Z, Peng H, Zheng J. HIV-infected macrophages mediate neuronal apoptosis through mitochondrial glutaminase Journal of Neurochemistry. 105: 994-1005. PMID 18088378 DOI: 10.1111/J.1471-4159.2007.05197.X  0.825
2008 Huang Y, Cui M, Erdmann N, Constantino AA, Zhao Y, Zheng J. Response to Comment on “Transcription Factor FOXO3a Mediates Apoptosis in HIV-1-Infected Macrophages” The Journal of Immunology. 180: 7783.2-7784. DOI: 10.4049/Jimmunol.180.12.7783-A  0.819
2007 Peng H, Kolb R, Kennedy JE, Zheng J. Differential expression of CXCL12 and CXCR4 during human fetal neural progenitor cell differentiation. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. 2: 251-8. PMID 18040858 DOI: 10.1007/S11481-007-9081-3  0.415
2007 Erdmann N, Zhao J, Lopez AL, Herek S, Curthoys N, Hexum TD, Tsukamoto T, Ferraris D, Zheng J. Glutamate production by HIV-1 infected human macrophage is blocked by the inhibition of glutaminase. Journal of Neurochemistry. 102: 539-49. PMID 17596215 DOI: 10.1111/J.1471-4159.2007.04594.X  0.844
2007 Haorah J, Knipe B, Gorantla S, Zheng J, Persidsky Y. Alcohol-induced blood-brain barrier dysfunction is mediated via inositol 1,4,5-triphosphate receptor (IP3R)-gated intracellular calcium release. Journal of Neurochemistry. 100: 324-36. PMID 17241155 DOI: 10.1111/J.1471-4159.2006.04245.X  0.597
2006 Erdmann NB, Whitney NP, Zheng J. Potentiation of Excitotoxicity in HIV-1 Associated Dementia and the Significance of Glutaminase. Clinical Neuroscience Research. 6: 315-328. PMID 18059978 DOI: 10.1016/J.Cnr.2006.09.009  0.83
2006 Peng H, Erdmann N, Whitney N, Dou H, Gorantla S, Gendelman HE, Ghorpade A, Zheng J. HIV-1-infected and/or immune activated macrophages regulate astrocyte SDF-1 production through IL-1beta. Glia. 54: 619-29. PMID 16944452 DOI: 10.1002/Glia.20409  0.824
2006 Huang Y, Erdmann N, Peng H, Herek S, Davis JS, Luo X, Ikezu T, Zheng J. TRAIL-mediated apoptosis in HIV-1-infected macrophages is dependent on the inhibition of Akt-1 phosphorylation. Journal of Immunology (Baltimore, Md. : 1950). 177: 2304-13. PMID 16887991 DOI: 10.4049/Jimmunol.177.4.2304  0.842
2005 Huang Y, Erdmann N, Zhao J, Zheng J. The signaling and apoptotic effects of TNF-related apoptosis-inducing ligand in HIV-1 associated dementia Neurotoxicity Research. 8: 135-148. PMID 16260391 DOI: 10.1007/Bf03033825  0.798
2005 Huang Y, Erdmann N, Peng H, Zhao Y, Zheng J. The role of TNF related apoptosis-inducing ligand in neurodegenerative diseases Cellular & Molecular Immunology. 2: 113-122. PMID 16191417  0.778
2005 Peng H, Huang Y, Duan Z, Erdmann N, Xu D, Herek S, Zheng J. Cellular IAP1 regulates TRAIL-induced apoptosis in human fetal cortical neural progenitor cells. Journal of Neuroscience Research. 82: 295-305. PMID 16180223 DOI: 10.1002/Jnr.20629  0.786
2005 Deshpande M, Zheng J, Borgmann K, Persidsky R, Wu L, Schellpeper C, Ghorpade A. Role of activated astrocytes in neuronal damage: potential links to HIV-1-associated dementia. Neurotoxicity Research. 7: 183-92. PMID 15897153 DOI: 10.1007/Bf03036448  0.688
2005 Kaul M, Zheng J, Okamoto S, Gendelman HE, Lipton SA. HIV-1 infection and AIDS: consequences for the central nervous system. Cell Death and Differentiation. 12: 878-92. PMID 15832177 DOI: 10.1038/Sj.Cdd.4401623  0.685
2004 Zheng J, Zhuang W, Yan N, Kou G, Peng H, McNally C, Erichsen D, Cheloha A, Herek S, Shi C. Classification of HIV-1-mediated neuronal dendritic and synaptic damage using multiple criteria linear programming. Neuroinformatics. 2: 303-26. PMID 15365193 DOI: 10.1385/Ni:2:3:303  0.461
2004 Peng H, Huang Y, Rose J, Erichsen D, Herek S, Fujii N, Tamamura H, Zheng J. Stromal cell-derived factor 1-mediated CXCR4 signaling in rat and human cortical neural progenitor cells. Journal of Neuroscience Research. 76: 35-50. PMID 15048928 DOI: 10.1002/Jnr.20045  0.679
2004 Ryan LA, Brester M, Bohac D, Morgello S, Zheng J. Up-regulation of soluble tumor necrosis factor receptor two in plasma of HIV-seropositive individuals who use opiates. Aids Research and Human Retroviruses. 20: 41-5. PMID 15000697 DOI: 10.1089/088922204322749486  0.666
2004 Ryan LA, Peng H, Erichsen DA, Huang Y, Persidsky Y, Zhou Y, Gendelman HE, Zheng J. TNF-related apoptosis-inducing ligand mediates human neuronal apoptosis: links to HIV-1-associated dementia. Journal of Neuroimmunology. 148: 127-39. PMID 14975593 DOI: 10.1016/J.Jneuroim.2003.11.019  0.846
2004 Zhao J, Lopez AL, Erichsen D, Herek S, Cotter RL, Curthoys NP, Zheng J. Mitochondrial glutaminase enhances extracellular glutamate production in HIV-1-infected macrophages: linkage to HIV-1 associated dementia. Journal of Neurochemistry. 88: 169-80. PMID 14675161 DOI: 10.1046/J.1471-4159.2003.02146.X  0.822
2003 Erichsen D, Lopez AL, Peng H, Niemann D, Williams C, Bauer M, Morgello S, Cotter RL, Ryan LA, Ghorpade A, Gendelman HE, Zheng J. Neuronal injury regulates fractalkine: relevance for HIV-1 associated dementia. Journal of Neuroimmunology. 138: 144-55. PMID 12742664 DOI: 10.1016/S0165-5728(03)00117-6  0.84
2003 Ikezu T, Luo X, Weber GA, Zhao J, McCabe L, Buescher JL, Ghorpade A, Zheng J, Xiong H. Amyloid precursor protein-processing products affect mononuclear phagocyte activation: pathways for sAPP- and Abeta-mediated neurotoxicity. Journal of Neurochemistry. 85: 925-34. PMID 12716424 DOI: 10.1046/J.1471-4159.2003.01739.X  0.625
2003 Luo X, Weber GA, Zheng J, Gendelman HE, Ikezu T. C1q-calreticulin induced oxidative neurotoxicity: relevance for the neuropathogenesis of Alzheimer's disease. Journal of Neuroimmunology. 135: 62-71. PMID 12576225 DOI: 10.1016/S0165-5728(02)00444-7  0.523
2003 Xiong H, Boyle J, Winkelbauer M, Gorantla S, Zheng J, Ghorpade A, Persidsky Y, Carlson KA, Gendelman HE. Inhibition of long-term potentiation by interleukin-8: implications for human immunodeficiency virus-1-associated dementia. Journal of Neuroscience Research. 71: 600-7. PMID 12548717 DOI: 10.1002/Jnr.10503  0.766
2002 Ryan LA, Cotter RL, Zink WE, Gendelman HE, Zheng J. Macrophages, chemokines and neuronal injury in HIV-1-associated dementia. Cellular and Molecular Biology (Noisy-Le-Grand, France). 48: 137-50. PMID 11995633  0.839
2001 Zheng J, Thylin MR, Persidsky Y, Williams CE, Cotter RL, Zink W, Ryan L, Ghorpade A, Lewis K, Gendelman HE. HIV-1 infected immune competent mononuclear phagocytes influence the pathways to neuronal demise. Neurotoxicity Research. 3: 461-84. PMID 14715459 DOI: 10.1007/Bf03033204  0.83
2001 Zheng J, Thylin MR, Cotter RL, Lopez AL, Ghorpade A, Persidsky Y, Xiong H, Leisman GB, Che MH, Gendelman HE. HIV-1 infected and immune competent mononuclear phagocytes induce quantitative alterations in neuronal dendritic arbor: relevance for HIV-1-associated dementia. Neurotoxicity Research. 3: 443-59. PMID 14715458 DOI: 10.1007/Bf03033203  0.845
2001 Ryan LA, Zheng J, Brester M, Bohac D, Hahn F, Anderson J, Ratanasuwan W, Gendelman HE, Swindells S. Plasma levels of soluble CD14 and tumor necrosis factor-alpha type II receptor correlate with cognitive dysfunction during human immunodeficiency virus type 1 infection. The Journal of Infectious Diseases. 184: 699-706. PMID 11517430 DOI: 10.1086/323036  0.723
2001 Jiang ZG, Piggee C, Heyes MP, Murphy C, Quearry B, Bauer M, Zheng J, Gendelman HE, Markey SP. Glutamate is a mediator of neurotoxicity in secretions of activated HIV-1-infected macrophages. Journal of Neuroimmunology. 117: 97-107. PMID 11431009 DOI: 10.1016/S0165-5728(01)00315-0  0.653
2001 Cotter RL, Zheng J, Che M, Niemann D, Liu Y, He J, Thomas E, Gendelman HE. Regulation of human immunodeficiency virus type 1 infection, beta-chemokine production, and CCR5 expression in CD40L-stimulated macrophages: immune control of viral entry. Journal of Virology. 75: 4308-20. PMID 11287580 DOI: 10.1128/Jvi.75.9.4308-4320.2001  0.823
2001 Zhang P, Zheng J, Bradley ME, Hexum TD. ATP stimulated cyclic AMP formation in bovine chromaffin cells is enhanced by neuropeptide Y. Peptides. 22: 439-44. PMID 11287099 DOI: 10.1016/S0196-9781(01)00354-0  0.643
2001 Persidsky Y, Limoges J, Rasmussen J, Zheng J, Gearing A, Gendelman HE. Reduction in glial immunity and neuropathology by a PAF antagonist and an MMP and TNFalpha inhibitor in SCID mice with HIV-1 encephalitis. Journal of Neuroimmunology. 114: 57-68. PMID 11240016 DOI: 10.1016/S0165-5728(00)00454-9  0.747
2000 Zheng J, Zhou G, Hexum TD. Neuropeptide Y secretion from bovine chromaffin cells inhibits cyclic AMP accumulation. Life Sciences. 67: 617-25. PMID 12659167 DOI: 10.1016/S0024-3205(00)00666-4  0.654
2000 Persidsky Y, Zheng J, Miller D, Gendelman HE. Mononuclear phagocytes mediate blood-brain barrier compromise and neuronal injury during HIV-1-associated dementia. Journal of Leukocyte Biology. 68: 413-22. PMID 10985259 DOI: 10.1189/Jlb.68.3.413  0.774
2000 Yeh MW, Kaul M, Zheng J, Nottet HS, Thylin M, Gendelman HE, Lipton SA. Cytokine-stimulated, but not HIV-infected, human monocyte-derived macrophages produce neurotoxic levels of l -cysteine. Journal of Immunology (Baltimore, Md. : 1950). 164: 4265-70. PMID 10754324 DOI: 10.4049/Jimmunol.164.8.4265  0.637
2000 Zhang P, Zheng J, Vorce RL, Hexum TD. Identification of an NPY-Y1 receptor subtype in bovine chromaffin cells. Regulatory Peptides. 87: 9-13. PMID 10710282 DOI: 10.1016/S0167-0115(99)00093-2  0.655
2000 Cotter RL, Carlson KA, Branecki CE, Zheng J, Ghorpade A, Thomas E, Gendelman HE. β-Amyloid priming and CD40L-mediated activation enhance cytokine and chemokine production in mononuclear phagocytes Neurobiology of Aging. 21: 258. DOI: 10.1016/S0197-4580(00)83111-5  0.767
1999 Zink WE, Zheng J, Persidsky Y, Poluektova L, Gendelman HE. The neuropathogenesis of HIV-1 infection. Fems Immunology and Medical Microbiology. 26: 233-41. PMID 10575134 DOI: 10.1111/J.1574-695X.1999.Tb01394.X  0.85
1999 Xiong H, Zeng YC, Zheng J, Thylin M, Gendelman HE. Soluble HIV-1 infected macrophage secretory products mediate blockade of long-term potentiation: a mechanism for cognitive dysfunction in HIV-1-associated dementia. Journal of Neurovirology. 5: 519-28. PMID 10568889 DOI: 10.3109/13550289909045381  0.631
1999 Zheng J, Ghorpade A, Niemann D, Cotter RL, Thylin MR, Epstein L, Swartz JM, Shepard RB, Liu X, Nukuna A, Gendelman HE. Lymphotropic virions affect chemokine receptor-mediated neural signaling and apoptosis: implications for human immunodeficiency virus type 1-associated dementia. Journal of Virology. 73: 8256-67. PMID 10482576 DOI: 10.1128/Jvi.73.10.8256-8267.1999  0.846
1999 Zheng J, Thylin MR, Ghorpade A, Xiong H, Persidsky Y, Cotter R, Niemann D, Che M, Zeng YC, Gelbard HA, Shepard RB, Swartz JM, Gendelman HE. Intracellular CXCR4 signaling, neuronal apoptosis and neuropathogenic mechanisms of HIV-1-associated dementia. Journal of Neuroimmunology. 98: 185-200. PMID 10430052 DOI: 10.1016/S0165-5728(99)00049-1  0.841
1999 Swindells S, Zheng J, Gendelman HE. HIV-associated dementia: new insights into disease pathogenesis and therapeutic interventions. Aids Patient Care and Stds. 13: 153-63. PMID 10375263 DOI: 10.1089/Apc.1999.13.153  0.662
1999 Cotter RL, Burke WJ, Thomas VS, Potter JF, Zheng J, Gendelman HE. Insights into the neurodegenerative process of Alzheimer's disease: a role for mononuclear phagocyte-associated inflammation and neurotoxicity. Journal of Leukocyte Biology. 65: 416-27. PMID 10204569 DOI: 10.1002/Jlb.65.4.416  0.786
1999 Xiong H, Zheng J, Thylin M, Gendelman HE. Unraveling the mechanisms of neurotoxicity in HIV type 1-associated dementia: inhibition of neuronal synaptic transmission by macrophage secretory products. Aids Research and Human Retroviruses. 15: 57-63. PMID 10024053 DOI: 10.1089/088922299311718  0.683
1998 Zhang P, Zheng J, Hexum TD. BIBP 3226 inhibition of nicotinic receptor mediated chromaffin cell secretion. European Journal of Pharmacology. 362: 121-5. PMID 9874161 DOI: 10.1016/S0014-2999(98)00729-8  0.655
1998 Gendelman HE, Zheng J, Coulter CL, Ghorpade A, Che M, Thylin M, Rubocki R, Persidsky Y, Hahn F, Reinhard J, Swindells S. Suppression of inflammatory neurotoxins by highly active antiretroviral therapy in human immunodeficiency virus-associated dementia. The Journal of Infectious Diseases. 178: 1000-7. PMID 9806027 DOI: 10.1086/515693  0.777
1997 Zheng J, Zhang P, Hexum TD. Neuropeptide Y inhibits chromaffin cell nicotinic receptor-stimulated tyrosine hydroxylase activity through a receptor-linked G protein-mediated process. Molecular Pharmacology. 52: 1027-33. PMID 9415712 DOI: 10.1124/Mol.52.6.1027  0.661
1997 Zheng J, Zhang P, Toews M, Hexum TD. Neuropeptide Y enhances ATP-induced formation of inositol phosphates in chromaffin cells. Biochemical and Biophysical Research Communications. 239: 287-90. PMID 9345312 DOI: 10.1006/Bbrc.1997.7456  0.658
1997 Zheng J, Gendelman HE. The HIV-1 associated dementia complex: a metabolic encephalopathy fueled by viral replication in mononuclear phagocytes. Current Opinion in Neurology. 10: 319-25. PMID 9266156 DOI: 10.1097/00019052-199708000-00007  0.647
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