Ping-Yee Law - Publications

Affiliations: 
University of Minnesota, Twin Cities, Minneapolis, MN 
Area:
Pharmacology, Molecular Biology, Neuroscience Biology

115 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Yang PP, Yeh TK, Loh HH, Law PY, Wang Y, Tao PL. Delta-opioid receptor antagonist naltrindole reduces oxycodone addiction and constipation in mice. European Journal of Pharmacology. PMID 30959048 DOI: 10.1016/j.ejphar.2019.04.009  0.56
2019 Chao PK, Chang HF, Ou LC, Chuang JY, Lee PT, Chang WT, Chen SC, Ueng SH, Hsu JT, Tao PL, Law PY, Loh HH, Yeh SH. Convallatoxin enhance the ligand-induced mu-opioid receptor endocytosis and attenuate morphine antinociceptive tolerance in mice. Scientific Reports. 9: 2405. PMID 30787373 DOI: 10.1038/s41598-019-39555-x  0.56
2019 Lin SY, Kuo YH, Tien YW, Ke YY, Chang WT, Chang HF, Ou LC, Law PY, Xi JH, Tao PL, Loh HH, Chao YS, Shih C, Chen CT, Yeh SH, et al. The in vivo antinociceptive and μ-opioid receptor activating effects of the combination of N-phenyl-2',4'-dimethyl-4,5'-bi-1,3-thiazol-2-amines and naloxone. European Journal of Medicinal Chemistry. 167: 312-323. PMID 30776693 DOI: 10.1016/j.ejmech.2019.01.063  0.56
2018 Fan W, Wang H, Zhang Y, Loh HH, Law PY, Xu C. Morphine regulates adult neurogenesis and contextual memory extinction via the PKCε/Prox1 pathway. Neuropharmacology. PMID 30170081 DOI: 10.1016/j.neuropharm.2018.08.031  0.56
2017 Zhang Y, Kibaly C, Xu C, Loh HH, Law PY. Temporal effect of manipulating NeuroD1 expression with the synthetic small molecule KHS101 on morphine contextual memory. Neuropharmacology. PMID 28842345 DOI: 10.1016/j.neuropharm.2017.08.030  0.56
2017 Zhang L, Kibaly C, Wang YJ, Xu C, Song KY, W McGarrah P, Loh HH, Liu JG, Law PY. Src-dependent phosphorylation of μ-opioid receptor at Tyr(336) modulates opiate withdrawal. Embo Molecular Medicine. PMID 28818835 DOI: 10.15252/emmm.201607324  0.56
2017 Lee DS, Law PY, Ln W, Loh HH, Song KY, Choi HS. Differential regulation of mouse and human Mu opioid receptor gene depends on the single stranded DNA structure of its promoter and α-complex protein 1. Biomedical Reports. 6: 532-538. PMID 28529734 DOI: 10.3892/br.2017.877  0.56
2017 Chao PK, Ueng SH, Ou LC, Yeh TK, Chang WT, Chang HF, Chen SC, Tao PL, Law PY, Loh HH, Cheng MF, Chuang JY, Chen CT, Shih C, Yeh SH. 1-(2,4-Dibromophenyl)-3,6,6-trimethyl-1,5,6,7-tetrahydro-4H-indazol-4-one: A Novel Opioid Receptor Agonist with Less Accompanying Gastrointestinal Dysfunction than Morphine. Anesthesiology. PMID 28212204 DOI: 10.1097/ALN.0000000000001568  0.56
2017 Kibaly C, Lin HY, Loh HH, Law PY. Spinal or supraspinal phosphorylation deficiency at the MOR C-terminus does not affect morphine tolerance in vivo. Pharmacological Research. PMID 28179123 DOI: 10.1016/j.phrs.2017.01.033  0.56
2017 Wagley Y, Law PY, Wei LN, Loh HH. Epigenetic activation of mu opioid receptor (MOR) gene via increased expression and function of mitogen- and stress-activated protein kinase 1 (MSK1). Molecular Pharmacology. PMID 28153853 DOI: 10.1124/mol.116.106567  0.56
2016 Hwang CK, Wagley Y, Law PY, Wei LN, Loh HH. Phosphorylation of poly(rC) binding protein 1 (PCBP1) contributes to stabilization of mu opioid receptor (MOR) mRNA via interaction with AU-rich element binding protein (AUF1) and poly A binding protein (PABP). Gene. PMID 27836661 DOI: 10.1016/j.gene.2016.11.003  0.56
2016 Chen SR, Ke YY, Yeh TK, Lin SY, Ou LC, Chen SC, Chang WT, Chang HF, Wu ZH, Hsieh CC, Law PY, Loh HH, Shih C, Lai YK, Yeh SH, et al. Discovery, structure-activity relationship studies, and anti-nociceptive effects of N-(1,2,3,4-tetrahydro-1-isoquinolinylmethyl)benzamides as novel opioid receptor agonists. European Journal of Medicinal Chemistry. 126: 202-217. PMID 27776274 DOI: 10.1016/j.ejmech.2016.09.003  0.56
2016 Yang PP, Yeh GC, Yeh TK, Xi J, Loh HH, Law PY, Tao PL. Activation of delta-opioid receptor contributes to the antinociceptive effect of oxycodone in mice. Pharmacological Research. PMID 27496654 DOI: 10.1016/j.phrs.2016.05.034  0.56
2016 Song KY, Choi HS, Law PY, Wei LN, Loh HH. Post-Transcriptional Regulation of the Human Mu-Opioid Receptor (MOR) by Morphine-Induced RNA Binding Proteins hnRNP K and PCBP1. Journal of Cellular Physiology. PMID 27292014 DOI: 10.1002/jcp.25455  0.56
2016 Zhang Y, Loh HH, Law PY. Effect of Opioid on Adult Hippocampal Neurogenesis. Thescientificworldjournal. 2016: 2601264. PMID 27127799 DOI: 10.1155/2016/2601264  0.56
2016 Zhang Y, Xu C, Zheng H, Loh HH, Law PY. Morphine Modulates Adult Neurogenesis and Contextual Memory by Impeding the Maturation of Neural Progenitors. Plos One. 11: e0153628. PMID 27078155 DOI: 10.1371/journal.pone.0153628  0.56
2016 Huang Z, Liang L, Li L, Xu M, Li X, Sun H, He S, Lin L, Zhang Y, Song Y, Yang M, Luo Y, Loh HH, Law PY, Zheng D, et al. Opioid doses required for pain management in lung cancer patients with different cholesterol levels: negative correlation between opioid doses and cholesterol levels. Lipids in Health and Disease. 15: 47. PMID 26952011 DOI: 10.1186/s12944-016-0212-9  0.56
2015 Xu C, Loh HH, Law PY. Effects of addictive drugs on adult neural stem/progenitor cells. Cellular and Molecular Life Sciences : Cmls. PMID 26468052 DOI: 10.1007/s00018-015-2067-z  0.56
2015 Yang PP, Yeh GC, Huang EY, Law PY, Loh HH, Tao PL. Effects of dextromethorphan and oxycodone on treatment of neuropathic pain in mice. Journal of Biomedical Science. 22: 81. PMID 26391752 DOI: 10.1186/s12929-015-0186-3  0.56
2015 Wang Y, Ge YH, Wang YX, Liu T, Law PY, Loh HH, Chen HZ, Qiu Y. Modulation of mTOR Activity by μ-Opioid Receptor is Dependent upon the Association of Receptor and FK506-Binding Protein 12. Cns Neuroscience & Therapeutics. 21: 591-8. PMID 26096047 DOI: 10.1111/cns.12409  0.56
2015 Kibaly C, Kam AY, Loh HH, Law PY. Naltrexone Facilitates Learning and Delays Extinction by Increasing AMPA Receptor Phosphorylation and Membrane Insertion. Biological Psychiatry. PMID 26049209 DOI: 10.1016/j.biopsych.2015.04.019  0.56
2015 Xu C, Zheng H, Loh HH, Law PY. Morphine Promotes Astrocyte-Preferential Differentiation of Mouse Hippocampal Progenitor Cells Via PKCε-Dependent ERK Activation and TRBP Phosphorylation. Stem Cells (Dayton, Ohio). PMID 26012717 DOI: 10.1002/stem.2055  0.56
2015 Hwang CK, Wagley Y, Law PY, Wei LN, Loh HH. Analysis of epigenetic mechanisms regulating opioid receptor gene transcription. Methods in Molecular Biology (Clifton, N.J.). 1230: 39-51. PMID 25293314 DOI: 10.1007/978-1-4939-1708-2_3  0.56
2015 Wang Y, Wang YX, Liu T, Law PY, Loh HH, Qiu Y, Chen HZ. μ-Opioid receptor attenuates Aβ oligomers-induced neurotoxicity through mTOR signaling. Cns Neuroscience & Therapeutics. 21: 8-14. PMID 25146548 DOI: 10.1111/cns.12316  0.56
2015 Kao JH, Gao MJ, Yang PP, Law PY, Loh HH, Tao PL. Effect of naltrexone on neuropathic pain in mice locally transfected with the mutant μ-opioid receptor gene in spinal cord. British Journal of Pharmacology. 172: 630-41. PMID 24866991 DOI: 10.1111/bph.12790  0.56
2014 Lee PT, Chao PK, Ou LC, Chuang JY, Lin YC, Chen SC, Chang HF, Law PY, Loh HH, Chao YS, Su TP, Yeh SH. Morphine drives internal ribosome entry site-mediated hnRNP K translation in neurons through opioid receptor-dependent signaling. Nucleic Acids Research. 42: 13012-25. PMID 25361975 DOI: 10.1093/nar/gku1016  0.56
2014 Cheng MF, Ou LC, Chen SC, Chang WT, Law PY, Loh HH, Chao YS, Shih C, Yeh SH, Ueng SH. Discovery, structure-activity relationship studies, and anti-nociceptive effects of 1-phenyl-3,6,6-trimethyl-1,5,6,7-tetrahydro-4H-indazol-4-one as novel opioid receptor agonists. Bioorganic & Medicinal Chemistry. 22: 4694-703. PMID 25087049 DOI: 10.1016/j.bmc.2014.07.012  0.56
2014 Li W, He S, Zhou Y, Li Y, Hao J, Zhou X, Wang F, Zhang Y, Huang Z, Li Z, Loh HH, Law PY, Zheng H. Neurod1 modulates opioid antinociceptive tolerance via two distinct mechanisms. Biological Psychiatry. 76: 775-84. PMID 24993058 DOI: 10.1016/j.biopsych.2014.05.013  0.56
2014 Xu C, Zhang Y, Zheng H, Loh HH, Law PY. Morphine modulates mouse hippocampal progenitor cell lineages by upregulating miR-181a level. Stem Cells (Dayton, Ohio). 32: 2961-72. PMID 24964978 DOI: 10.1002/stem.1774  0.56
2014 Glück L, Loktev A, Moulédous L, Mollereau C, Law PY, Schulz S. Loss of morphine reward and dependence in mice lacking G protein-coupled receptor kinase 5. Biological Psychiatry. 76: 767-74. PMID 24629717 DOI: 10.1016/j.biopsych.2014.01.021  0.56
2014 Yan YH, Wang Y, Zhao LX, Jiang S, Loh HH, Law PY, Chen HZ, Qiu Y. Role of FK506 binding protein 12 in morphine-induced μ-opioid receptor internalization and desensitization. Neuroscience Letters. 566: 231-5. PMID 24607931 DOI: 10.1016/j.neulet.2014.02.059  0.56
2014 Qiu Y, Zhao W, Wang Y, Xu JR, Huie E, Jiang S, Yan YH, Loh HH, Chen HZ, Law PY. FK506-binding protein 12 modulates μ-opioid receptor phosphorylation and protein kinase C(ε)-dependent signaling by its direct interaction with the receptor. Molecular Pharmacology. 85: 37-49. PMID 24113748 DOI: 10.1124/mol.113.087825  0.56
2014 Frazier TW, Ratliff KR, Gruber C, Zhang Y, Law PA, Constantino JN. Confirmatory factor analytic structure and measurement invariance of quantitative autistic traits measured by the social responsiveness scale-2. Autism : the International Journal of Research and Practice. 18: 31-44. PMID 24019124 DOI: 10.1177/1362361313500382  0.32
2014 Kibaly C, Kam AYF, Loh HH, Law PY. Naltrexone Facilitates Learning and Delays Extinction by Increasing AMPA Receptor Phosphorylation and Membrane Insertion Biological Psychiatry. DOI: 10.1016/j.biopsych.2015.04.019  0.56
2013 Zhang L, Loh HH, Law PY. A novel noncanonical signaling pathway for the μ-opioid receptor. Molecular Pharmacology. 84: 844-53. PMID 24061856 DOI: 10.1124/mol.113.088278  0.56
2013 Kang DH, Song KY, Wei LN, Law PY, Loh HH, Choi HS. Novel function of the poly(c)-binding protein α-CP2 as a transcriptional activator that binds to single-stranded DNA sequences. International Journal of Molecular Medicine. 32: 1187-94. PMID 24026233 DOI: 10.3892/ijmm.2013.1488  0.56
2013 Law PY, Reggio PH, Loh HH. Opioid receptors: toward separation of analgesic from undesirable effects. Trends in Biochemical Sciences. 38: 275-82. PMID 23598157 DOI: 10.1016/j.tibs.2013.03.003  0.56
2013 Wagley Y, Hwang CK, Lin HY, Kam AF, Law PY, Loh HH, Wei LN. Inhibition of c-Jun NH2-terminal kinase stimulates mu opioid receptor expression via p38 MAPK-mediated nuclear NF-κB activation in neuronal and non-neuronal cells. Biochimica Et Biophysica Acta. 1833: 1476-88. PMID 23485395 DOI: 10.1016/j.bbamcr.2013.02.017  0.56
2013 Zheng H, Loh HH, Law PY. Posttranslation modification of G protein-coupled receptor in relationship to biased agonism. Methods in Enzymology. 522: 391-408. PMID 23374194 DOI: 10.1016/B978-0-12-407865-9.00018-2  0.56
2013 Song KY, Choi HS, Law PY, Wei LN, Loh HH. Vimentin interacts with the 5'-untranslated region of mouse mu opioid receptor (MOR) and is required for post-transcriptional regulation. Rna Biology. 10: 256-66. PMID 23353576 DOI: 10.4161/rna.23022  0.56
2013 Zheng H, Zhang Y, Li W, Loh HH, Law PY. NeuroD modulates opioid agonist-selective regulation of adult neurogenesis and contextual memory extinction. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 38: 770-7. PMID 23303051 DOI: 10.1038/npp.2012.242  0.56
2013 Wu Q, Hwang CK, Zheng H, Wagley Y, Lin HY, Kim do K, Law PY, Loh HH, Wei LN. MicroRNA 339 down-regulates μ-opioid receptor at the post-transcriptional level in response to opioid treatment. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 27: 522-35. PMID 23085997 DOI: 10.1096/fj.12-213439  0.56
2013 Constantino JN, Todorov A, Hilton C, Law P, Zhang Y, Molloy E, Fitzgerald R, Geschwind D. Autism recurrence in half siblings: strong support for genetic mechanisms of transmission in ASD. Molecular Psychiatry. 18: 137-8. PMID 22371046 DOI: 10.1038/mp.2012.9  0.32
2012 Zheng H, Law PY, Loh HH. Non-Coding RNAs Regulating Morphine Function: With Emphasis on the In vivo and In vitro Functions of miR-190. Frontiers in Genetics. 3: 113. PMID 22715342 DOI: 10.3389/fgene.2012.00113  0.56
2012 Miller EC, Zhang L, Dummer BW, Cariveau DR, Loh H, Law PY, Liao D. Differential modulation of drug-induced structural and functional plasticity of dendritic spines. Molecular Pharmacology. 82: 333-43. PMID 22596350 DOI: 10.1124/mol.112.078162  0.56
2012 Kang DH, Song KY, Choi HS, Law PY, Wei LN, Loh HH. Novel dual-binding function of a poly (C)-binding protein 3, transcriptional factor which binds the double-strand and single-stranded DNA sequence. Gene. 501: 33-8. PMID 22521865 DOI: 10.1016/j.gene.2012.04.001  0.56
2012 Zheng H, Pearsall EA, Hurst DP, Zhang Y, Chu J, Zhou Y, Reggio PH, Loh HH, Law PY. Palmitoylation and membrane cholesterol stabilize μ-opioid receptor homodimerization and G protein coupling. Bmc Cell Biology. 13: 6. PMID 22429589 DOI: 10.1186/1471-2121-13-6  0.56
2012 Chou SH, Kao JH, Tao PL, Law PY, Loh HH. Naloxone can act as an analgesic agent without measurable chronic side effects in mice with a mutant mu-opioid receptor expressed in different sites of pain pathway. Synapse (New York, N.Y.). 66: 694-704. PMID 22407757 DOI: 10.1002/syn.21555  0.56
2012 Zheng H, Zou H, Liu X, Chu J, Zhou Y, Loh HH, Law PY. Cholesterol level influences opioid signaling in cell models and analgesia in mice and humans. Journal of Lipid Research. 53: 1153-62. PMID 22377533 DOI: 10.1194/jlr.M024455  0.56
2012 Lin HY, Law PY, Loh HH. Activation of protein kinase C (PKC)α or PKCε as an approach to increase morphine tolerance in respiratory depression and lethal overdose. The Journal of Pharmacology and Experimental Therapeutics. 341: 115-25. PMID 22228806 DOI: 10.1124/jpet.111.188235  0.56
2012 Hwang CK, Wagley Y, Law PY, Wei LN, Loh HH. MicroRNAs in opioid pharmacology. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. 7: 808-19. PMID 22068836 DOI: 10.1007/s11481-011-9323-2  0.56
2012 Song KY, Choi HS, Law PY, Wei LN, Loh HH. Post-transcriptional regulation of mu-opioid receptor: role of the RNA-binding proteins heterogeneous nuclear ribonucleoprotein H1 and F. Cellular and Molecular Life Sciences : Cmls. 69: 599-610. PMID 21739230 DOI: 10.1007/s00018-011-0761-z  0.56
2011 Choe CY, Kim H, Dong J, van Wijnen AJ, Law PY, Loh HH. The polypyrimidine/polypurine motif in the mouse mu opioid receptor gene promoter is a supercoiling-regulatory element. Gene. 487: 52-61. PMID 21839154 DOI: 10.1016/j.gene.2011.07.026  0.56
2011 Qiu Y, Wang Y, Law PY, Chen HZ, Loh HH. Cholesterol regulates micro-opioid receptor-induced beta-arrestin 2 translocation to membrane lipid rafts. Molecular Pharmacology. 80: 210-8. PMID 21518774 DOI: 10.1124/mol.110.070870  0.56
2011 Zheng H, Chu J, Zhang Y, Loh HH, Law PY. Modulating micro-opioid receptor phosphorylation switches agonist-dependent signaling as reflected in PKCepsilon activation and dendritic spine stability. The Journal of Biological Chemistry. 286: 12724-33. PMID 21292762 DOI: 10.1074/jbc.M110.177089  0.56
2011 Kim do K, Hwang CK, Wagley Y, Law PY, Wei LN, Loh HH. p38 mitogen-activated protein kinase and PI3-kinase are involved in up-regulation of mu opioid receptor transcription induced by cycloheximide. Journal of Neurochemistry. 116: 1077-87. PMID 21198637 DOI: 10.1111/j.1471-4159.2010.07163.x  0.56
2011 Choe CY, Dong J, Law PY, Loh HH. Differential gene expression activity among species-specific polypyrimidine/polypurine motifs in mu opioid receptor gene promoters. Gene. 471: 27-36. PMID 20946943 DOI: 10.1016/j.gene.2010.10.004  0.56
2011 Zhao H, Xiao S, Kong X, Wang J, Cao X, Gencheng W, Loh HH, Law PY. Neuron-glial cell communication in the traumatic stress-induced immunomodulation. Synapse (New York, N.Y.). 65: 433-40. PMID 20853446 DOI: 10.1002/syn.20861  0.56
2010 Kam AY, Liao D, Loh HH, Law PY. Morphine induces AMPA receptor internalization in primary hippocampal neurons via calcineurin-dependent dephosphorylation of GluR1 subunits. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 15304-16. PMID 21068335 DOI: 10.1523/JNEUROSCI.4255-10.2010  0.56
2010 Sanchez-Simon FM, Zhang XX, Loh HH, Law PY, Rodriguez RE. Morphine regulates dopaminergic neuron differentiation via miR-133b. Molecular Pharmacology. 78: 935-42. PMID 20716624 DOI: 10.1124/mol.110.066837  0.56
2010 Zheng H, Zeng Y, Chu J, Kam AY, Loh HH, Law PY. Modulations of NeuroD activity contribute to the differential effects of morphine and fentanyl on dendritic spine stability. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 8102-10. PMID 20554861 DOI: 10.1523/JNEUROSCI.6069-09.2010  0.56
2010 Zheng H, Chu J, Zeng Y, Loh HH, Law PY. Yin Yang 1 phosphorylation contributes to the differential effects of mu-opioid receptor agonists on microRNA-190 expression. The Journal of Biological Chemistry. 285: 21994-2002. PMID 20457614 DOI: 10.1074/jbc.M110.112607  0.56
2010 Chen SL, Ma HI, Han JM, Lu RB, Tao PL, Law PY, Loh HH. Antinociceptive effects of morphine and naloxone in mu-opioid receptor knockout mice transfected with the MORS196A gene. Journal of Biomedical Science. 17: 28. PMID 20403204 DOI: 10.1186/1423-0127-17-28  0.56
2010 Hwang CK, Kim CS, Kim do K, Law PY, Wei LN, Loh HH. Up-regulation of the mu-opioid receptor gene is mediated through chromatin remodeling and transcriptional factors in differentiated neuronal cells. Molecular Pharmacology. 78: 58-68. PMID 20385708 DOI: 10.1124/mol.110.064311  0.56
2010 Zheng H, Loh HH, Law PY. Agonist-selective signaling of G protein-coupled receptor: mechanisms and implications. Iubmb Life. 62: 112-9. PMID 20058265 DOI: 10.1002/iub.293  0.56
2010 Chu J, Zheng H, Zhang Y, Loh HH, Law PY. Agonist-dependent mu-opioid receptor signaling can lead to heterologous desensitization. Cellular Signalling. 22: 684-96. PMID 20043990 DOI: 10.1016/j.cellsig.2009.12.003  0.56
2010 Tao PL, Law PY, Loh HH. Search for the "ideal analgesic" in pain treatment by engineering the mu-opioid receptor. Iubmb Life. 62: 103-11. PMID 20039371 DOI: 10.1002/iub.292  0.56
2010 Joiner ML, Lisé MF, Yuen EY, Kam AY, Zhang M, Hall DD, Malik ZA, Qian H, Chen Y, Ulrich JD, Burette AC, Weinberg RJ, Law PY, El-Husseini A, Yan Z, et al. Assembly of a beta2-adrenergic receptor--GluR1 signalling complex for localized cAMP signalling. The Embo Journal. 29: 482-95. PMID 19942860 DOI: 10.1038/emboj.2009.344  0.56
2010 Zheng H, Zeng Y, Zhang X, Chu J, Loh HH, Law PY. mu-Opioid receptor agonists differentially regulate the expression of miR-190 and NeuroD. Molecular Pharmacology. 77: 102-9. PMID 19854889 DOI: 10.1124/mol.109.060848  0.56
2010 Song KY, Kim CS, Hwang CK, Choi HS, Law PY, Wei LN, Loh HH. uAUG-mediated translational initiations are responsible for human mu opioid receptor gene expression. Journal of Cellular and Molecular Medicine. 14: 1113-24. PMID 19438807 DOI: 10.1111/j.1582-4934.2009.00734.x  0.56
2009 Ge X, Qiu Y, Loh HH, Law PY. GRIN1 regulates micro-opioid receptor activities by tethering the receptor and G protein in the lipid raft. The Journal of Biological Chemistry. 284: 36521-34. PMID 19861419 DOI: 10.1074/jbc.M109.024109  0.56
2009 Song KY, Choi HS, Hwang CK, Kim CS, Law PY, Wei LN, Loh HH. Differential use of an in-frame translation initiation codon regulates human mu opioid receptor (OPRM1). Cellular and Molecular Life Sciences : Cmls. 66: 2933-42. PMID 19609488 DOI: 10.1007/s00018-009-0082-7  0.56
2009 Hwang CK, Song KY, Kim CS, Choi HS, Guo XH, Law PY, Wei LN, Loh HH. Epigenetic programming of mu-opioid receptor gene in mouse brain is regulated by MeCP2 and Brg1 chromatin remodelling factor. Journal of Cellular and Molecular Medicine. 13: 3591-615. PMID 19602036 DOI: 10.1111/j.1582-4934.2008.00535.x  0.56
2009 Zhao H, Cao X, Wu G, Loh HH, Law PY. Neurite outgrowth is dependent on the association of c-Src and lipid rafts. Neurochemical Research. 34: 2197-205. PMID 19529986 DOI: 10.1007/s11064-009-0016-7  0.56
2009 Lin H, Higgins P, Loh HH, Law PY, Liao D. Bidirectional effects of fentanyl on dendritic spines and AMPA receptors depend upon the internalization of mu opioid receptors. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 34: 2097-111. PMID 19295508 DOI: 10.1038/npp.2009.34  0.56
2009 Ge X, Loh HH, Law PY. mu-Opioid receptor cell surface expression is regulated by its direct interaction with Ribophorin I. Molecular Pharmacology. 75: 1307-16. PMID 19289571 DOI: 10.1124/mol.108.054064  0.56
2009 Choi HS, Hwang CK, Song KY, Law PY, Wei LN, Loh HH. Poly(C)-binding proteins as transcriptional regulators of gene expression. Biochemical and Biophysical Research Communications. 380: 431-6. PMID 19284986 DOI: 10.1016/j.bbrc.2009.01.136  0.56
2009 Wu Q, Zhang L, Law PY, Wei LN, Loh HH. Long-term morphine treatment decreases the association of mu-opioid receptor (MOR1) mRNA with polysomes through miRNA23b. Molecular Pharmacology. 75: 744-50. PMID 19144786 DOI: 10.1124/mol.108.053462  0.56
2009 Zhang L, Zhao H, Qiu Y, Loh HH, Law PY. Src phosphorylation of micro-receptor is responsible for the receptor switching from an inhibitory to a stimulatory signal. The Journal of Biological Chemistry. 284: 1990-2000. PMID 19029294 DOI: 10.1074/jbc.M807971200  0.56
2008 Wu Q, Law PY, Wei LN, Loh HH. Post-transcriptional regulation of mouse mu opioid receptor (MOR1) via its 3' untranslated region: a role for microRNA23b. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 22: 4085-95. PMID 18716031 DOI: 10.1096/fj.08-108175  0.56
2008 Kim CS, Hwang CK, Song KY, Choi HS, Kim do K, Law PY, Wei LN, Loh HH. Novel function of neuron-restrictive silencer factor (NRSF) for posttranscriptional regulation. Biochimica Et Biophysica Acta. 1783: 1835-46. PMID 18657578 DOI: 10.1016/j.bbamcr.2008.06.019  0.56
2008 Zheng H, Chu J, Qiu Y, Loh HH, Law PY. Agonist-selective signaling is determined by the receptor location within the membrane domains. Proceedings of the National Academy of Sciences of the United States of America. 105: 9421-6. PMID 18599439 DOI: 10.1073/pnas.0802253105  0.56
2008 Chu J, Zheng H, Loh HH, Law PY. Morphine-induced mu-opioid receptor rapid desensitization is independent of receptor phosphorylation and beta-arrestins. Cellular Signalling. 20: 1616-24. PMID 18558479 DOI: 10.1016/j.cellsig.2008.05.004  0.56
2008 Choi HS, Song KY, Hwang CK, Kim CS, Law PY, Wei LN, Loh HH. A proteomics approach for identification of single strand DNA-binding proteins involved in transcriptional regulation of mouse mu opioid receptor gene. Molecular & Cellular Proteomics : McP. 7: 1517-29. PMID 18453338 DOI: 10.1074/mcp.M800052-MCP200  0.56
2008 Chen YL, Law PY, Loh HH. The other side of the opioid story: modulation of cell growth and survival signaling. Current Medicinal Chemistry. 15: 772-8. PMID 18393846 DOI: 10.2174/092986708783955518  0.56
2008 Chen YL, Law PY, Loh HH. NGF/PI3K signaling-mediated epigenetic regulation of delta opioid receptor gene expression. Biochemical and Biophysical Research Communications. 368: 755-60. PMID 18269915 DOI: 10.1016/j.bbrc.2008.01.164  0.56
2008 Choi HS, Hwang CK, Kim CS, Song KY, Law PY, Loh HH, Wei LN. Transcriptional regulation of mouse mu opioid receptor gene in neuronal cells by poly(ADP-ribose) polymerase-1. Journal of Cellular and Molecular Medicine. 12: 2319-33. PMID 18266974 DOI: 10.1111/j.1582-4934.2008.00259.x  0.56
2008 Zheng H, Loh HH, Law PY. Beta-arrestin-dependent mu-opioid receptor-activated extracellular signal-regulated kinases (ERKs) Translocate to Nucleus in Contrast to G protein-dependent ERK activation. Molecular Pharmacology. 73: 178-90. PMID 17947509 DOI: 10.1124/mol.107.039842  0.56
2007 Choi HS, Kim CS, Hwang CK, Song KY, Law PY, Wei LN, Loh HH. Novel function of the poly(C)-binding protein alpha CP3 as a transcriptional repressor of the mu opioid receptor gene. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 21: 3963-73. PMID 17625070 DOI: 10.1096/fj.07-8561com  0.56
2007 Qiu Y, Loh HH, Law PY. Phosphorylation of the delta-opioid receptor regulates its beta-arrestins selectivity and subsequent receptor internalization and adenylyl cyclase desensitization. The Journal of Biological Chemistry. 282: 22315-23. PMID 17565992 DOI: 10.1074/jbc.M611258200  0.56
2007 Liao D, Grigoriants OO, Wang W, Wiens K, Loh HH, Law PY. Distinct effects of individual opioids on the morphology of spines depend upon the internalization of mu opioid receptors. Molecular and Cellular Neurosciences. 35: 456-69. PMID 17513124 DOI: 10.1016/j.mcn.2007.04.007  0.56
2007 Hwang CK, Song KY, Kim CS, Choi HS, Guo XH, Law PY, Wei LN, Loh HH. Evidence of endogenous mu opioid receptor regulation by epigenetic control of the promoters. Molecular and Cellular Biology. 27: 4720-36. PMID 17452465 DOI: 10.1128/MCB.00073-07  0.56
2007 Song KY, Hwang CK, Kim CS, Choi HS, Law PY, Wei LN, Loh HH. Translational repression of mouse mu opioid receptor expression via leaky scanning. Nucleic Acids Research. 35: 1501-13. PMID 17284463 DOI: 10.1093/nar/gkm034  0.56
2007 Chen YL, Law PY, Loh HH. Action of NF-kappaB on the delta opioid receptor gene promoter. Biochemical and Biophysical Research Communications. 352: 818-22. PMID 17150179 DOI: 10.1016/j.bbrc.2006.11.103  0.56
2007 Liao D, Grigoriants OO, Loh HH, Law PY. Agonist-dependent postsynaptic effects of opioids on miniature excitatory postsynaptic currents in cultured hippocampal neurons. Journal of Neurophysiology. 97: 1485-94. PMID 17122315 DOI: 10.1152/jn.00790.2006  0.56
2006 Chen YL, Law PY, Loh HH. Nuclear factor kappaB signaling in opioid functions and receptor gene expression. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. 1: 270-9. PMID 18040804 DOI: 10.1007/s11481-006-9028-0  0.56
2006 Kim CS, Choi HS, Hwang CK, Song KY, Lee BK, Law PY, Wei LN, Loh HH. Evidence of the neuron-restrictive silencer factor (NRSF) interaction with Sp3 and its synergic repression to the mu opioid receptor (MOR) gene. Nucleic Acids Research. 34: 6392-403. PMID 17130167 DOI: 10.1093/nar/gkl724  0.56
2006 Choi HS, Kim CS, Hwang CK, Song KY, Wang W, Qiu Y, Law PY, Wei LN, Loh HH. The opioid ligand binding of human mu-opioid receptor is modulated by novel splice variants of the receptor. Biochemical and Biophysical Research Communications. 343: 1132-40. PMID 16580639 DOI: 10.1016/j.bbrc.2006.03.084  0.56
2006 Zhang L, Tetrault J, Wang W, Loh HH, Law PY. Short- and long-term regulation of adenylyl cyclase activity by delta-opioid receptor are mediated by Galphai2 in neuroblastoma N2A cells. Molecular Pharmacology. 69: 1810-9. PMID 16525132 DOI: 10.1124/mol.105.021352  0.56
2006 Chen YL, Law PY, Loh HH. Sustained activation of phosphatidylinositol 3-kinase/Akt/nuclear factor kappaB signaling mediates G protein-coupled delta-opioid receptor gene expression. The Journal of Biological Chemistry. 281: 3067-74. PMID 16316997 DOI: 10.1074/jbc.M506721200  0.56
2005 Daniels DJ, Lenard NR, Etienne CL, Law PY, Roerig SC, Portoghese PS. Opioid-induced tolerance and dependence in mice is modulated by the distance between pharmacophores in a bivalent ligand series. Proceedings of the National Academy of Sciences of the United States of America. 102: 19208-13. PMID 16365317 DOI: 10.1073/pnas.0506627102  0.56
2005 Kim SS, Pandey KK, Choi HS, Kim SY, Law PY, Wei LN, Loh HH. Poly(C) binding protein family is a transcription factor in mu-opioid receptor gene expression. Molecular Pharmacology. 68: 729-36. PMID 15933215 DOI: 10.1124/mol.105.012245  0.56
2005 Wu Q, Hwang CK, Yao S, Law PY, Loh HH, Wei LN. A major species of mouse mu-opioid receptor mRNA and its promoter-dependent functional polyadenylation signal. Molecular Pharmacology. 68: 279-85. PMID 15879516 DOI: 10.1124/mol.105.012567  0.56
2005 Wang G, Liu T, Wei LN, Law PY, Loh HH. DNA methylation-related chromatin modification in the regulation of mouse delta-opioid receptor gene. Molecular Pharmacology. 67: 2032-9. PMID 15769948 DOI: 10.1124/mol.105.011056  0.56
2005 Choi HS, Hwang CK, Kim CS, Song KY, Law PY, Wei LN, Loh HH. Transcriptional regulation of mouse mu opioid receptor gene: Sp3 isoforms (M1, M2) function as repressors in neuronal cells to regulate the mu opioid receptor gene. Molecular Pharmacology. 67: 1674-83. PMID 15703380 DOI: 10.1124/mol.104.008284  0.56
2005 Law PY, Erickson-Herbrandson LJ, Zha QQ, Solberg J, Chu J, Sarre A, Loh HH. Heterodimerization of mu- and delta-opioid receptors occurs at the cell surface only and requires receptor-G protein interactions. The Journal of Biological Chemistry. 280: 11152-64. PMID 15657030 DOI: 10.1074/jbc.M500171200  0.56
2005 Claude-Geppert PA, Liu J, Solberg J, Erickson-Herbrandson LJ, Loh HH, Law PY. Antagonist efficacy in MORS196L mutant is affected by the interaction between transmembrane domains of the opioid receptor. The Journal of Pharmacology and Experimental Therapeutics. 313: 216-26. PMID 15579496 DOI: 10.1124/jpet.104.076505  0.56
2004 Kim CS, Hwang CK, Choi HS, Song KY, Law PY, Wei LN, Loh HH. Neuron-restrictive silencer factor (NRSF) functions as a repressor in neuronal cells to regulate the mu opioid receptor gene. The Journal of Biological Chemistry. 279: 46464-73. PMID 15322094 DOI: 10.1074/jbc.M403633200  0.56
2004 Wei LN, Law PY, Loh HH. Post-transcriptional regulation of opioid receptors in the nervous system. Frontiers in Bioscience : a Journal and Virtual Library. 9: 1665-79. PMID 14977578  0.56
2003 Portoghese PS, Law PY, Loh HH. Effect of opioid receptor ligands on the mu-S196A knock-in and mu knockout mouse vas deferens. European Journal of Pharmacology. 478: 207-10. PMID 14575806 DOI: 10.1016/j.ejphar.2003.08.041  0.56
2003 Qiu Y, Law PY, Loh HH. Mu-opioid receptor desensitization: role of receptor phosphorylation, internalization, and representation. The Journal of Biological Chemistry. 278: 36733-9. PMID 12860981 DOI: 10.1074/jbc.M305857200  0.56
2003 Wang W, Loh HH, Law PY. The intracellular trafficking of opioid receptors directed by carboxyl tail and a di-leucine motif in Neuro2A cells. The Journal of Biological Chemistry. 278: 36848-58. PMID 12851402 DOI: 10.1074/jbc.M301540200  0.56
2003 Chaipatikul V, Erickson-Herbrandson LJ, Loh HH, Law PY. Rescuing the traffic-deficient mutants of rat mu-opioid receptors with hydrophobic ligands. Molecular Pharmacology. 64: 32-41. PMID 12815158 DOI: 10.1124/mol.64.1.32  0.56
2003 Chaipatikul V, Loh HH, Law PY. Ligand-selective activation of mu-oid receptor: demonstrated with deletion and single amino acid mutations of third intracellular loop domain. The Journal of Pharmacology and Experimental Therapeutics. 305: 909-18. PMID 12626655 DOI: 10.1124/jpet.102.046219  0.56
2003 Yang W, Law PY, Guo X, Loh HH. In vivo activation of a mutant mu-opioid receptor by antagonist: future direction for opiate pain treatment paradigm that lacks undesirable side effects. Proceedings of the National Academy of Sciences of the United States of America. 100: 2117-21. PMID 12525693 DOI: 10.1073/pnas.0334906100  0.56
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