| Year |
Citation |
Score |
| 2023 |
Lerin C, Collado MC, Isganaitis E, Arning E, Wasek B, Demerath EW, Fields DA, Bottiglieri T. Revisiting One-Carbon Metabolites in Human Breast Milk: Focus on S-Adenosylmethionine. Nutrients. 15. PMID 36678154 DOI: 10.3390/nu15020282 |
0.726 |
|
| 2022 |
Shen JS, Balaji U, Shigeyasu K, Okugawa Y, Jabbarzadeh-Tabrizi S, Day TS, Arning E, Marshall J, Cheng SH, Gu J, Schiffmann R, Bottiglieri T, Goel A. Dysregulated DNA methylation in the pathogenesis of Fabry disease. Molecular Genetics and Metabolism Reports. 33: 100919. PMID 36186841 DOI: 10.1016/j.ymgmr.2022.100919 |
0.473 |
|
| 2022 |
Arning E, Wasek B, Bottiglieri T. Quantitation of 5-Methyltetrahydrofolate in Cerebrospinal Fluid Using Liquid Chromatography-Electrospray-Tandem Mass Spectrometry. Methods in Molecular Biology (Clifton, N.J.). 2546: 311-319. PMID 36127600 DOI: 10.1007/978-1-0716-2565-1_28 |
0.739 |
|
| 2022 |
Wasek B, Arning E. Quantitation of Lactate in Cerebrospinal Fluid Using Liquid Chromatography-Electrospray-Tandem Mass Spectrometry. Methods in Molecular Biology (Clifton, N.J.). 2546: 253-260. PMID 36127595 DOI: 10.1007/978-1-0716-2565-1_23 |
0.696 |
|
| 2022 |
Arning E, Wasek B, Bottiglieri T. Quantitation of γ-Aminobutyric Acid in Cerebrospinal Fluid Using Liquid Chromatography-Electrospray-Tandem Mass Spectrometry. Methods in Molecular Biology (Clifton, N.J.). 2546: 165-174. PMID 36127587 DOI: 10.1007/978-1-0716-2565-1_15 |
0.725 |
|
| 2022 |
Arning E, Wasek B, Bottiglieri T. Quantification of Plasma S-adenosylmethionine and S-adenosylhomocysteine Using Liquid Chromatography-Electrospray-Tandem Mass Spectrometry. Methods in Molecular Biology (Clifton, N.J.). 2546: 35-43. PMID 36127576 DOI: 10.1007/978-1-0716-2565-1_4 |
0.722 |
|
| 2022 |
Bobrowski-Khoury N, Sequeira JM, Arning E, Bottiglieri T, Quadros EV. Absorption and Tissue Distribution of Folate Forms in Rats: Indications for Specific Folate Form Supplementation during Pregnancy. Nutrients. 14. PMID 35745126 DOI: 10.3390/nu14122397 |
0.485 |
|
| 2022 |
May T, de la Haye B, Nord G, Klatt K, Stephenson K, Adams S, Bollinger L, Hanchard N, Arning E, Bottiglieri T, Maleta K, Manary M, Jahoor F. One-carbon metabolism in children with marasmus and kwashiorkor. Ebiomedicine. 75: 103791. PMID 35030356 DOI: 10.1016/j.ebiom.2021.103791 |
0.442 |
|
| 2021 |
Bottiglieri T, Wang X, Arning E, Fernandez H, Wall A, McKenna G, Ruiz R, Onaca N, Trotter J, Lawrence M, Naziruddin B, Asrani SK, Testa G. Longitudinal profiling of plasma and urine metabolites during liver regeneration in living liver donors. Clinical Transplantation. e14490. PMID 34545967 DOI: 10.1111/ctr.14490 |
0.445 |
|
| 2021 |
Cedars A, Manlhiot C, Ko JM, Bottiglieri T, Arning E, Weingarten A, Opotowsky A, Kutty S. Metabolomic Profiling of Adults with Congenital Heart Disease. Metabolites. 11. PMID 34436466 DOI: 10.3390/metabo11080525 |
0.498 |
|
| 2021 |
Panetta JC, Liu Y, Bottiglieri T, Arning E, Cheng C, Karol SE, Yang JJ, Zhou Y, Inaba H, Pui CH, Jeha S, Relling MV. Pharmacodynamics of cerebrospinal fluid asparagine after asparaginase. Cancer Chemotherapy and Pharmacology. PMID 34170389 DOI: 10.1007/s00280-021-04315-0 |
0.397 |
|
| 2021 |
Ribo S, Sánchez-Infantes D, Martinez-Guino L, García-Mantrana I, Ramon-Krauel M, Tondo M, Arning E, Nofrarías M, Osorio-Conles Ó, Fernández-Pérez A, González-Torres P, Cebrià J, Gavaldà-Navarro A, Chenoll E, Isganaitis E, et al. Increasing breast milk betaine modulates abundance in mammalian neonates and improves long-term metabolic health. Science Translational Medicine. 13. PMID 33790021 DOI: 10.1126/scitranslmed.abb0322 |
0.452 |
|
| 2020 |
Walters DC, Jansen EEW, Salomons GS, Arning E, Ashcraft P, Bottiglieri T, Roullet JB, Gibson KM. Preferential accumulation of the active S-(+) isomer in murine retina highlights novel mechanisms of vigabatrin-associated retinal toxicity. Epilepsy Research. 170: 106536. PMID 33385945 DOI: 10.1016/j.eplepsyres.2020.106536 |
0.468 |
|
| 2020 |
Pannia E, Hammoud R, Simonian R, Arning E, Ashcraft P, Wasek B, Bottiglieri T, Pausova Z, Kubant R, Anderson GH. [6]-5-Methyltetrahydrofolic Acid and Folic Acid Pregnancy Diets Differentially Program Metabolic Phenotype and Hypothalamic Gene Expression of Wistar Rat Dams Post-Birth. Nutrients. 13. PMID 33375730 DOI: 10.3390/nu13010048 |
0.729 |
|
| 2020 |
Brown MN, Gibson KM, Schmidt MA, Walters DC, Arning E, Bottiglieri T, Roullet JB. Cellular and molecular outcomes of glutamine supplementation in the brain of succinic semialdehyde dehydrogenase-deficient mice. Jimd Reports. 56: 58-69. PMID 33204597 DOI: 10.1002/jmd2.12151 |
0.534 |
|
| 2020 |
Kirby T, Walters DC, Shi X, Turgeon C, Rinaldo P, Arning E, Ashcraft P, Bottiglieri T, DiBacco M, Pearl PL, Roullet JB, Gibson KM. Novel biomarkers and age-related metabolite correlations in plasma and dried blood spots from patients with succinic semialdehyde dehydrogenase deficiency. Orphanet Journal of Rare Diseases. 15: 261. PMID 32967698 DOI: 10.1186/s13023-020-01522-5 |
0.477 |
|
| 2020 |
Christine CW, Auinger P, Saleh N, Tian M, Bottiglieri T, Arning E, Tran NK, Ueland PM, Green R. Relationship of Cerebrospinal Fluid Vitamin B12 Status Markers With Parkinson's Disease Progression. Movement Disorders : Official Journal of the Movement Disorder Society. PMID 32407590 DOI: 10.1002/mds.28073 |
0.452 |
|
| 2020 |
Kirby T, Walters DC, Brown M, Jansen E, Salomons GS, Turgeon C, Rinaldo P, Arning E, Ashcraft P, Bottiglieri T, Roullet JB, Gibson KM. Correction to: Post-mortem tissue analyses in a patient with succinic semialdehyde dehydrogenase deficiency (SSADHD). I. Metabolomic outcomes. Metabolic Brain Disease. PMID 32306187 DOI: 10.1007/S11011-020-00569-4 |
0.44 |
|
| 2020 |
Kirby T, Walters DC, Brown M, Jansen E, Salomons GS, Turgeon C, Rinaldo P, Arning E, Ashcraft P, Bottiglieri T, Roullet JB, Gibson KM. Post-mortem tissue analyses in a patient with succinic semialdehyde dehydrogenase deficiency (SSADHD). I. Metabolomic outcomes. Metabolic Brain Disease. PMID 32172518 DOI: 10.1007/S11011-020-00550-1 |
0.509 |
|
| 2020 |
Tondo M, Wasek B, Escola-Gil JC, Gonzalo-Calvo Dd, Harmon C, Arning E, Bottiglieri T. Altered Brain Metabolome Is Associated with Memory Impairment in the rTg4510 Mouse Model of Tauopathy. Metabolites. 10: 69. PMID 32075035 DOI: 10.3390/Metabo10020069 |
0.75 |
|
| 2020 |
Gu SX, Sonkar VK, Katare PB, Kumar R, Kruger WD, Arning E, Bottiglieri T, Lentz SR, Dayal S. Memantine Protects From Exacerbation of Ischemic Stroke and Blood Brain Barrier Disruption in Mild But Not Severe Hyperhomocysteinemia. Journal of the American Heart Association. 9: e013368. PMID 32067580 DOI: 10.1161/Jaha.119.013368 |
0.56 |
|
| 2019 |
Jadavji NM, Mosnier H, Kelly E, Lawrence K, Cruickshank S, Stacey S, McCall A, Dhatt S, Arning E, Bottiglieri T, Smith PD. One-carbon metabolism supplementation improves outcome after stroke in aged male MTHFR-deficient mice. Neurobiology of Disease. 104613. PMID 31525435 DOI: 10.1016/J.Nbd.2019.104613 |
0.5 |
|
| 2019 |
Brown M, Ashcraft P, Arning E, Bottiglieri T, Roullet JB, Gibson KM. Gamma-Hydroxybutyrate content in dried bloodspots facilitates newborn detection of succinic semialdehyde dehydrogenase deficiency. Molecular Genetics and Metabolism. PMID 31345667 DOI: 10.1016/j.ymgme.2019.07.010 |
0.507 |
|
| 2019 |
Abu Ahmad N, Raizman M, Weizmann N, Wasek B, Arning E, Bottiglieri T, Tirosh O, Troen AM. Betaine attenuates pathology by stimulating lipid oxidation in liver and regulating phospholipid metabolism in brain of methionine-choline-deficient rats. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. fj201802683R. PMID 31120771 DOI: 10.1096/Fj.201802683R |
0.751 |
|
| 2019 |
Brown MN, Walters DC, Schmidt MA, Hill J, McConnell A, Jansen E, Salomons GS, Arning E, Bottiglieri T, Gibson KM, Roullet JB. Maternal Glutamine Supplementation in Murine Succinic Semialdehyde Dehydrogenase Deficiency (SSADHD), a Disorder of GABA Metabolism. Journal of Inherited Metabolic Disease. PMID 31032972 DOI: 10.1002/jimd.12107 |
0.526 |
|
| 2019 |
Brown M, Ashcraft P, Arning E, Bottiglieri T, McClintock W, Giancola F, Lieberman D, Hauser NS, Miller R, Roullet JB, Pearl P, Gibson KM. Rett syndrome (MECP2) and succinic semialdehyde dehydrogenase (ALDH5A1) deficiency in a developmentally delayed female. Molecular Genetics & Genomic Medicine. e629. PMID 30829465 DOI: 10.1002/Mgg3.629 |
0.431 |
|
| 2019 |
Walters DC, Arning E, Bottiglieri T, Jansen EEW, Salomons GS, Brown MN, Schmidt MA, Ainslie GR, Roullet JB, Gibson KM. Metabolomic analyses of vigabatrin (VGB)-Treated mice: GABA-transaminase inhibition significantly alters amino acid profiles in murine neural and non-neural tissues. Neurochemistry International. PMID 30822440 DOI: 10.1016/j.neuint.2019.02.015 |
0.474 |
|
| 2019 |
Czysz AH, South C, Gadad BS, Arning E, Soyombo A, Bottiglieri T, Trivedi MH. Can targeted metabolomics predict depression recovery? Results from the CO-MED trial. Translational Psychiatry. 9: 11. PMID 30664617 DOI: 10.1038/s41398-018-0349-6 |
0.419 |
|
| 2018 |
Arora K, Sequeira JM, Alarcon JM, Wasek B, Arning E, Bottiglieri T, Quadros EV. Neuropathology of vitamin B deficiency in the Cd320 mouse. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. fj201800754RR. PMID 30303736 DOI: 10.1096/Fj.201800754Rr |
0.74 |
|
| 2018 |
Dheda K, Lenders L, Magombedze G, Srivastava S, Raj P, Arning E, Ashcraft P, Bottiglieri T, Wainwright H, Pennel T, Linegar A, Moodley L, Pooran A, Pasipanodya JG, Sirgel FA, et al. Drug Penetration Gradients Associated with Acquired Drug Resistance in Tuberculosis Patients. American Journal of Respiratory and Critical Care Medicine. PMID 29877726 DOI: 10.1164/Rccm.201711-2333Oc |
0.382 |
|
| 2018 |
Hoffman A, Taleski G, Qian H, Wasek B, Arning E, Bottiglieri T, Sontag JM, Sontag E. Methylenetetrahydrofolate Reductase Deficiency Deregulates Regional Brain Amyloid-β Protein Precursor Expression and Phosphorylation Levels. Journal of Alzheimer's Disease : Jad. 64: 223-237. PMID 29865064 DOI: 10.3233/Jad-180032 |
0.759 |
|
| 2018 |
Wasek B, Arning E, Bottiglieri T. The use of microwave irradiation for quantitative analysis of neurotransmitters in the mouse brain. Journal of Neuroscience Methods. 307: 188-193. PMID 29802857 DOI: 10.1016/J.Jneumeth.2018.05.016 |
0.757 |
|
| 2018 |
Christensen KE, Bahous RH, Hou W, Deng L, Malysheva OV, Arning E, Bottiglieri T, Caudill MA, Jerome-Majewska LA, Rozen R. Low Dietary Folate Interacts with MTHFD1 Synthetase Deficiency in Mice, a Model for the R653Q Variant, to Increase Incidence of Developmental Delays and Defects. The Journal of Nutrition. 148: 501-509. PMID 29659962 DOI: 10.1093/Jn/Nxy013 |
0.519 |
|
| 2018 |
Majtan T, Bublil EM, Park I, Arning E, Bottiglieri T, Glavin F, Kraus JP. Pharmacokinetics and pharmacodynamics of PEGylated truncated human cystathionine beta-synthase as treatment for homocystinuria. Life Sciences. PMID 29526799 DOI: 10.1016/j.lfs.2018.03.018 |
0.459 |
|
| 2017 |
Meng XL, Arning E, Wight-Carter M, Day TS, Jabbarzadeh-Tabrizi S, Chen S, Ziegler RJ, Bottiglieri T, Schneider JW, Cheng SH, Schiffmann R, Shen JS. Priapism in a Fabry disease mouse model is associated with upregulated penile nNOS and eNOS expression. Journal of Inherited Metabolic Disease. PMID 29110178 DOI: 10.1007/S10545-017-0107-6 |
0.565 |
|
| 2017 |
Dayal S, Baumbach GL, Arning E, Bottiglieri T, Faraci FM, Lentz SR. Deficiency of superoxide dismutase promotes cerebral vascular hypertrophy and vascular dysfunction in hyperhomocysteinemia. Plos One. 12: e0175732. PMID 28414812 DOI: 10.1371/Journal.Pone.0175732 |
0.551 |
|
| 2017 |
Belik J, Shifrin Y, Arning E, Bottiglieri T, Pan J, Daigneault MC, Allen-Vercoe E. Corrigendum: Intestinal microbiota as a tetrahydrobiopterin exogenous source in hph-1 mice. Scientific Reports. 7: 44161. PMID 28398297 DOI: 10.1038/Srep44161 |
0.418 |
|
| 2017 |
Shen JS, Arning E, West ML, Day TS, Chen S, Meng XL, Forni S, McNeill N, Goker-Alpan O, Wang X, Ashcraft P, Moore DF, Cheng SH, Schiffmann R, Bottiglieri T. Tetrahydrobiopterin deficiency in the pathogenesis of Fabry disease. Human Molecular Genetics. PMID 28158561 DOI: 10.1093/Hmg/Ddx032 |
0.547 |
|
| 2017 |
Belik J, Shifrin Y, Arning E, Bottiglieri T, Pan J, Daigneault MC, Allen-Vercoe E. Intestinal microbiota as a tetrahydrobiopterin exogenous source in hph-1 mice. Scientific Reports. 7: 39854. PMID 28079055 DOI: 10.1038/Srep39854 |
0.53 |
|
| 2017 |
Shen J, Arning E, West ML, Day TS, Cheng SH, Schiffmann R, Bottiglieri T. Tetrahydrobiopterin deficiency in the pathogenesis of Fabry disease Molecular Genetics and Metabolism. 120. DOI: 10.1016/J.Ymgme.2016.11.319 |
0.508 |
|
| 2016 |
Vogel KR, Arning E, Bottiglieri T, Gibson KM. Multicompartment analysis of protein-restricted phenylketonuric mice reveals amino acid imbalances in brain. Journal of Inherited Metabolic Disease. PMID 27761676 DOI: 10.1007/S10545-016-9984-3 |
0.571 |
|
| 2016 |
Christensen KE, Hou W, Bahous RH, Deng L, Malysheva OV, Arning E, Bottiglieri T, Caudill MA, Jerome-Majewska LA, Rozen R. Moderate folic acid supplementation and MTHFD1-synthetase deficiency in mice, a model for the R653Q variant, result in embryonic defects and abnormal placental development. The American Journal of Clinical Nutrition. PMID 27707701 DOI: 10.3945/Ajcn.116.139519 |
0.553 |
|
| 2016 |
Wexler O, Gough MS, Morgan MA, Mack CM, Apostolakos MJ, Doolin KP, Mooney RA, Arning E, Bottiglieri T, Pietropaoli AP. Methionine Metabolites in Patients With Sepsis. Journal of Intensive Care Medicine. PMID 27591199 DOI: 10.1177/0885066616666002 |
0.533 |
|
| 2016 |
Arning E, Bottiglieri T. Erratum to: LC-MS/MS Analysis of Cerebrospinal Fluid Metabolites in the Pterin Biosynthetic Pathway. Jimd Reports. 29: 115. PMID 27272191 DOI: 10.1007/8904_2014_372 |
0.45 |
|
| 2016 |
Nicholls RE, Sontag JM, Zhang H, Staniszewski A, Yan S, Kim CY, Yim M, Woodruff CM, Arning E, Wasek B, Yin D, Bottiglieri T, Sontag E, Kandel ER, Arancio O. PP2A methylation controls sensitivity and resistance to β-amyloid-induced cognitive and electrophysiological impairments. Proceedings of the National Academy of Sciences of the United States of America. PMID 26951658 DOI: 10.1073/Pnas.1521018113 |
0.739 |
|
| 2016 |
Arning E, Bottiglieri T. Quantitation of S-Adenosylmethionine and S-Adenosylhomocysteine in Plasma Using Liquid Chromatography-Electrospray Tandem Mass Spectrometry Methods of Molecular Biology. 1378: 255-262. PMID 26602137 DOI: 10.1007/978-1-4939-3182-8_27 |
0.527 |
|
| 2016 |
Arning E, Bottiglieri T. Quantitation of 5-Methyltetrahydrofolate in Cerebrospinal Fluid Using Liquid Chromatography-Electrospray Tandem Mass Spectrometry. Methods of Molecular Biology. 1378: 175-182. PMID 26602129 DOI: 10.1007/978-1-4939-3182-8_19 |
0.546 |
|
| 2016 |
Arning E, Bottiglieri T. Quantification of γ-Aminobutyric Acid in Cerebrospinal Fluid Using Liquid Chromatography-Electrospray Tandem Mass Spectrometry. Methods of Molecular Biology. 1378: 109-118. PMID 26602123 DOI: 10.1007/978-1-4939-3182-8_13 |
0.528 |
|
| 2016 |
Arning E, Bottiglieri T. LC-MS/MS Analysis of Cerebrospinal Fluid Metabolites in the Pterin Biosynthetic Pathway. Jimd Reports. 29: 1-9. PMID 25213568 DOI: 10.1007/8904_2014_336 |
0.487 |
|
| 2015 |
Singhal NK, Li S, Arning E, Alkhayer K, Clements R, Sarcyk Z, Dassanayake RS, Brasch NE, Freeman EJ, Bottiglieri T, McDonough J. Changes in Methionine Metabolism and Histone H3 Trimethylation Are Linked to Mitochondrial Defects in Multiple Sclerosis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 15170-86. PMID 26558787 DOI: 10.1523/Jneurosci.4349-14.2015 |
0.545 |
|
| 2015 |
Vogel KR, Ainslie GR, Phillips B, Arning E, Bottiglieri T, Shen DD, Gibson KM. Physiological Competition of Brain Phenylalanine Accretion: Initial Pharmacokinetic Analyses of Aminoisobutyric and Methylaminoisobutyric Acids in Pah(enu2-/-) Mice. Molecular Genetics and Metabolism Reports. 3: 80-87. PMID 26120559 DOI: 10.1016/J.Ymgmr.2015.03.009 |
0.573 |
|
| 2015 |
Strauss KA, Ferreira C, Bottiglieri T, Zhao X, Arning E, Zhang S, Zeisel SH, Escolar ML, Presnick N, Puffenberger EG, Vugrek O, Kovacevic L, Wagner C, Mazariegos GV, Mudd SH, et al. Liver transplantation for treatment of severe S-adenosylhomocysteine hydrolase deficiency. Molecular Genetics and Metabolism. PMID 26095522 DOI: 10.1016/J.Ymgme.2015.06.005 |
0.523 |
|
| 2014 |
Dayal S, Blokhin IO, Erger RA, Jensen M, Arning E, Stevens JW, Bottiglieri T, Faraci FM, Lentz SR. Protective vascular and cardiac effects of inducible nitric oxide synthase in mice with hyperhomocysteinemia. Plos One. 9: e107734. PMID 25226386 DOI: 10.1371/Journal.Pone.0107734 |
0.548 |
|
| 2014 |
Sontag JM, Wasek B, Taleski G, Smith J, Arning E, Sontag E, Bottiglieri T. Altered protein phosphatase 2A methylation and Tau phosphorylation in the young and aged brain of methylenetetrahydrofolate reductase (MTHFR) deficient mice. Frontiers in Aging Neuroscience. 6: 214. PMID 25202269 DOI: 10.3389/fnagi.2014.00214 |
0.766 |
|
| 2014 |
Fang P, Zhang D, Cheng Z, Yan C, Jiang X, Kruger WD, Meng S, Arning E, Bottiglieri T, Choi ET, Han Y, Yang XF, Wang H. Hyperhomocysteinemia potentiates hyperglycemia-induced inflammatory monocyte differentiation and atherosclerosis. Diabetes. 63: 4275-90. PMID 25008174 DOI: 10.2337/Db14-0809 |
0.552 |
|
| 2014 |
Vogel KR, Arning E, Wasek BL, McPherson S, Bottiglieri T, Gibson KM. Brain-blood amino acid correlates following protein restriction in murine maple syrup urine disease. Orphanet Journal of Rare Diseases. 9: 73. PMID 24886632 DOI: 10.1186/1750-1172-9-73 |
0.738 |
|
| 2014 |
Harding CO, Winn SR, Gibson KM, Arning E, Bottiglieri T, Grompe M. Pharmacologic inhibition of L-tyrosine degradation ameliorates cerebral dopamine deficiency in murine phenylketonuria (PKU). Journal of Inherited Metabolic Disease. 37: 735-43. PMID 24487571 DOI: 10.1007/S10545-013-9675-2 |
0.541 |
|
| 2014 |
Yano S, Moseley K, Bottiglieri T, Arning E, Azen C. Maternal Phenylketonuria International Collaborative Study revisited: evaluation of maternal nutritional risk factors besides phenylalanine for fetal congenital heart defects Journal of Inherited Metabolic Disease. 37: 39-42. PMID 23784316 DOI: 10.1007/S10545-013-9627-X |
0.518 |
|
| 2014 |
Arning E, Shen J, LeMoine K, Schiffmann R, West M, Bottiglieri T. Tetrahydrobiopterin in Fabry disease Molecular Genetics and Metabolism. 111. DOI: 10.1016/J.Ymgme.2013.12.027 |
0.473 |
|
| 2013 |
Vogel KR, Arning E, Wasek BL, Bottiglieri T, Gibson KM. Characterization of 2-(methylamino)alkanoic acid capacity to restrict blood-brain phenylalanine transport in Pah enu2 mice: preliminary findings. Molecular Genetics and Metabolism. 110: S71-8. PMID 23999161 DOI: 10.1016/J.Ymgme.2013.08.004 |
0.75 |
|
| 2013 |
Inoue-Choi M, Nelson HH, Robien K, Arning E, Bottiglieri T, Koh WP, Yuan JM. Plasma S-adenosylmethionine, DNMT polymorphisms, and peripheral blood LINE-1 methylation among healthy Chinese adults in Singapore. Bmc Cancer. 13: 389. PMID 23957506 DOI: 10.1186/1471-2407-13-389 |
0.498 |
|
| 2013 |
Butler LM, Arning E, Wang R, Bottiglieri T, Govindarajan S, Gao YT, Yuan JM. Prediagnostic levels of serum one-carbon metabolites and risk of hepatocellular carcinoma. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 22: 1884-93. PMID 23897582 DOI: 10.1158/1055-9965.Epi-13-0497 |
0.502 |
|
| 2013 |
Christensen KE, Deng L, Leung KY, Arning E, Bottiglieri T, Malysheva OV, Caudill MA, Krupenko NI, Greene ND, Jerome-Majewska L, MacKenzie RE, Rozen R. A novel mouse model for genetic variation in 10-formyltetrahydrofolate synthetase exhibits disturbed purine synthesis with impacts on pregnancy and embryonic development Human Molecular Genetics. 22: 3705-3719. PMID 23704330 DOI: 10.1093/Hmg/Ddt223 |
0.534 |
|
| 2013 |
Skvorak KJ, Dorko K, Marongiu F, Tahan V, Hansel MC, Gramignoli R, Arning E, Bottiglieri T, Gibson KM, Strom SC. Improved amino acid, bioenergetic metabolite and neurotransmitter profiles following human amnion epithelial cell transplant in intermediate maple syrup urine disease mice. Molecular Genetics and Metabolism. 109: 132-8. PMID 23566440 DOI: 10.1016/J.Ymgme.2013.02.011 |
0.552 |
|
| 2013 |
Vogel KR, Arning E, Wasek BL, Bottiglieri T, Gibson KM. Non-physiological amino acid (NPAA) therapy targeting brain phenylalanine reduction: pilot studies in PAHENU2 mice. Journal of Inherited Metabolic Disease. 36: 513-23. PMID 22976763 DOI: 10.1007/S10545-012-9524-8 |
0.745 |
|
| 2012 |
Bottiglieri T, Arning E, Wasek B, Nunbhakdi-Craig V, Sontag J, Sontag E. Acute administration of L-DOPA induces changes in methylation metabolites, reduced protein phosphatase 2A methylation, and hyperphosphorylation of Tau protein in mouse brain. The Journal of Neuroscience. 32: 9173-9181. PMID 22764226 DOI: 10.1523/Jneurosci.0125-12.2012 |
0.746 |
|
| 2012 |
Inoue-Choi M, Nelson HH, Robien K, Arning E, Bottiglieri T, Koh WP, Yuan JM. One-carbon metabolism nutrient status and plasma S-adenosylmethionine concentrations in middle-aged and older Chinese in Singapore. International Journal of Molecular Epidemiology and Genetics. 3: 160-73. PMID 22724053 |
0.478 |
|
| 2012 |
Mischoulon D, Alpert JE, Arning E, Bottiglieri T, Fava M, Papakostas GI. Bioavailability of S-adenosyl methionine and impact on response in a randomized, double-blind, placebo-controlled trial in major depressive disorder. The Journal of Clinical Psychiatry. 73: 843-8. PMID 22687580 DOI: 10.4088/Jcp.11M07139 |
0.457 |
|
| 2012 |
Inoue-Choi M, Nelson HH, Robien K, Arning E, Bottiglieri T, Koh W, Yuan J. Abstract 1038: PlasmaS-adenosylmethionine levels, genetic polymorphisms ofDNMT1andDNMT3A, and LINE-1 DNA methylation among Chinese in Singapore Cancer Research. 72: 1038-1038. DOI: 10.1158/1538-7445.Am2012-1038 |
0.505 |
|
| 2011 |
Gough MS, Morgan MA, Mack CM, Darling DC, Frasier LM, Doolin KP, Apostolakos MJ, Stewart JC, Graves BT, Arning E, Bottiglieri T, Mooney RA, Frampton MW, Pietropaoli AP. The ratio of arginine to dimethylarginines is reduced and predicts outcomes in patients with severe sepsis. Critical Care Medicine. 39: 1351-8. PMID 21378552 DOI: 10.1097/Ccm.0B013E318212097C |
0.44 |
|
| 2010 |
Rodionov RN, Dayoub H, Lynch CM, Wilson KM, Stevens JW, Murry DJ, Kimoto M, Arning E, Bottiglieri T, Cooke JP, Baumbach GL, Faraci FM, Lentz SR. Overexpression of dimethylarginine dimethylaminohydrolase protects against cerebral vascular effects of hyperhomocysteinemia. Circulation Research. 106: 551-8. PMID 20019334 DOI: 10.1161/Circresaha.109.200360 |
0.498 |
|
| 2009 |
Roe CR, Bottiglieri T, Wallace M, Arning E, Martin A. Adult Polyglucosan Body Disease (APBD): Anaplerotic diet therapy (Triheptanoin) and demonstration of defective methylation pathways Molecular Genetics and Metabolism. 101: 246-252. PMID 20655781 DOI: 10.1016/J.Ymgme.2010.06.017 |
0.496 |
|
| 2009 |
Skvorak KJ, Hager EJ, Arning E, Bottiglieri T, Paul HS, Strom SC, Homanics GE, Sun Q, Jansen EE, Jakobs C, Zinnanti WJ, Gibson KM. Hepatocyte transplantation (HTx) corrects selected neurometabolic abnormalities in murine intermediate maple syrup urine disease (iMSUD). Biochimica Et Biophysica Acta. 1792: 1004-10. PMID 19699299 DOI: 10.1016/J.Bbadis.2009.08.006 |
0.512 |
|
| 2009 |
Li S, Arning E, Liu C, Vitvitsky V, Hernandez C, Banerjee R, Bottiglieri T, Lin JD. Regulation of homocysteine homeostasis through the transcriptional coactivator PGC-1alpha. American Journal of Physiology. Endocrinology and Metabolism. 296: E543-8. PMID 19158324 DOI: 10.1152/Ajpendo.90719.2008 |
0.478 |
|
| 2009 |
Roe C, Arning E, Bottiglieri T, Reuser A. 117. IGF-1 resistance is a reversible feature of late-onset acid maltase deficiency (AMD) Molecular Genetics and Metabolism. 96. DOI: 10.1016/J.Ymgme.2008.11.118 |
0.494 |
|
| 2008 |
Sontag JM, Nunbhakdi-Craig V, Montgomery L, Arning E, Bottiglieri T, Sontag E. Folate deficiency induces in vitro and mouse brain region-specific downregulation of leucine carboxyl methyltransferase-1 and protein phosphatase 2A B(alpha) subunit expression that correlate with enhanced tau phosphorylation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 11477-87. PMID 18987184 DOI: 10.1523/Jneurosci.2816-08.2008 |
0.5 |
|
| 2008 |
Dayal S, Rodionov RN, Arning E, Bottiglieri T, Kimoto M, Murry DJ, Cooke JP, Faraci FM, Lentz SR. Tissue-specific downregulation of dimethylarginine dimethylaminohydrolase in hyperhomocysteinemia American Journal of Physiology - Heart and Circulatory Physiology. 295: H816-H825. PMID 18567702 DOI: 10.1152/Ajpheart.01348.2007 |
0.419 |
|
| 2008 |
Dayoub H, Rodionov R, Lynch C, Cooke JP, Arning E, Bottiglieri T, Lentz SR, Faraci FM. Overexpression of dimethylarginine dimethylaminohydrolase inhibits asymmetric dimethylarginine-induced endothelial dysfunction in the cerebral circulation Stroke. 39: 180-184. PMID 18063827 DOI: 10.1161/Strokeaha.107.490631 |
0.509 |
|
| 2007 |
Sontag E, Nunbhakdi-Craig V, Sontag JM, Diaz-Arrastia R, Ogris E, Dayal S, Lentz SR, Arning E, Bottiglieri T. Protein phosphatase 2A methyltransferase links homocysteine metabolism with tau and amyloid precursor protein regulation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 2751-9. PMID 17360897 DOI: 10.1523/Jneurosci.3316-06.2007 |
0.507 |
|
| 2007 |
Wilson KM, McCaw RB, Leo L, Arning E, Lhoták S, Bottiglieri T, Austin RC, Lentz SR. Prothrombotic effects of hyperhomocysteinemia and hypercholesterolemia in ApoE-deficient mice. Arteriosclerosis, Thrombosis, and Vascular Biology. 27: 233-40. PMID 17082485 DOI: 10.1161/01.Atv.0000251607.96118.Af |
0.485 |
|
| 2006 |
Dayal S, Wilson KM, Leo L, Arning E, Bottiglieri T, Lentz SR. Enhanced susceptibility to arterial thrombosis in a murine model of hyperhomocysteinemia. Blood. 108: 2237-43. PMID 16804115 DOI: 10.1182/Blood-2006-02-005991 |
0.483 |
|
| 2005 |
Dayal S, Devlin AM, McCaw RB, Liu ML, Arning E, Bottiglieri T, Shane B, Faraci FM, Lentz SR. Cerebral vascular dysfunction in methionine synthase-deficient mice Circulation. 112: 737-744. PMID 16043641 DOI: 10.1161/CIRCULATIONAHA.104.529248 |
0.558 |
|
| 2004 |
Duncan GE, Perri MG, Anton SD, Limacher MC, Martin AD, Lowenthal DT, Arning E, Bottiglieri T, Stacpoole PW. Effects of exercise on emerging and traditional cardiovascular risk factors. Preventive Medicine. 39: 894-902. PMID 15475021 DOI: 10.1016/J.Ypmed.2004.03.012 |
0.481 |
|
| 2004 |
Goff DC, Bottiglieri T, Arning E, Shih V, Freudenreich O, Evins AE, Henderson DC, Baer L, Coyle J. Folate, homocysteine, and negative symptoms in schizophrenia American Journal of Psychiatry. 161: 1705-1708. PMID 15337665 DOI: 10.1176/Appi.Ajp.161.9.1705 |
0.444 |
|
| 2004 |
Dayal S, Arning E, Bottiglieri T, Böger RH, Sigmund CD, Faraci FM, Lentz SR. Cerebral vascular dysfunction mediated by superoxide in hyperhomocysteinemic mice. Stroke; a Journal of Cerebral Circulation. 35: 1957-62. PMID 15178827 DOI: 10.1161/01.Str.0000131749.81508.18 |
0.462 |
|
| 2004 |
Quinn CT, Griener JC, Bottiglieri T, Arning E, Winick NJ. Effects of intraventricular methotrexate on folate, adenosine, and homocysteine metabolism in cerebrospinal fluid. Journal of Pediatric Hematology/Oncology. 26: 386-8. PMID 15167354 DOI: 10.1097/00043426-200406000-00011 |
0.504 |
|
| 2004 |
Devlin AM, Arning E, Bottiglieri T, Faraci FM, Rozen R, Lentz SR. Effect of Mthfr genotype on diet-induced hyperhomocysteinemia and vascular function in mice Blood. 103: 2624-2629. PMID 14630804 DOI: 10.1182/Blood-2003-09-3078 |
0.515 |
|
| 2002 |
Dayal S, Brown KL, Weydert CJ, Oberley LW, Arning E, Bottiglieri T, Faraci FM, Lentz SR. Deficiency of glutathione peroxidase-1 sensitizes hyperhomocysteinemic mice to endothelial dysfunction. Arteriosclerosis, Thrombosis, and Vascular Biology. 22: 1996-2002. PMID 12482825 DOI: 10.1161/01.Atv.0000041629.92741.Dc |
0.505 |
|
| 2002 |
Lentz SR, Piegors DJ, Fernández JA, Erger RA, Arning E, René Malinow M, Griffin JH, Bottiglieri T, Haynes WG, Heistad DD. Effect of hyperhomocysteinemia on protein C activation and activity Blood. 100: 2108-2112. PMID 12200374 DOI: 10.1182/Blood-2002-03-0727 |
0.479 |
|
| 2001 |
Bottiglieri T, Parnetti L, Arning E, Ortiz T, Amici S, Lanari A, Gallai V. Plasma total homocysteine levels and the C677T mutation in the methylenetetrahydrofolate reductase (MTHFR) gene: a study in an Italian population with dementia. Mechanisms of Ageing and Development. 122: 2013-2023. PMID 11589919 DOI: 10.1016/S0047-6374(01)00307-4 |
0.524 |
|
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