Peter Hegemann, PhD - Publications

Affiliations: 
Experimental Biophysics Humboldt-Universität zu Berlin, Berlin, Germany 
Area:
microbial opsins

195 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Vogt A, Silapetere A, Grimm C, Heiser F, Ancina Möller M, Hegemann P. Engineered Passive Potassium Conductance in the KR2 Sodium Pump. Biophysical Journal. PMID 31036257 DOI: 10.1016/j.bpj.2019.04.001  0.6
2019 Kuhne J, Vierock J, Tennigkeit SA, Dreier MA, Wietek J, Petersen D, Gavriljuk K, El-Mashtoly SF, Hegemann P, Gerwert K. Unifying photocycle model for light adaptation and temporal evolution of cation conductance in channelrhodopsin-2. Proceedings of the National Academy of Sciences of the United States of America. PMID 31004059 DOI: 10.1073/pnas.1818707116  0.64
2019 Mukherjee S, Hegemann P, Broser M. Enzymerhodopsins: novel photoregulated catalysts for optogenetics. Current Opinion in Structural Biology. 57: 118-126. PMID 30954887 DOI: 10.1016/j.sbi.2019.02.003  0.44
2019 Giliberti V, Polito R, Ritter E, Broser M, Hegemann P, Puskar L, Schade U, Zanetti-Polzi L, Daidone I, Corni S, Rusconi F, Biagioni P, Baldassarre L, Ortolani M. Tip-enhanced Infrared Difference-Nanospectroscopy of the Proton Pump Activity of Bacteriorhodopsin in Single Purple Membrane Patches. Nano Letters. PMID 30950626 DOI: 10.1021/acs.nanolett.9b00512  0.44
2019 Fudim R, Szczepek M, Vierock J, Vogt A, Schmidt A, Kleinau G, Fischer P, Bartl F, Scheerer P, Hegemann P. Design of a light-gated proton channel based on the crystal structure of rhodopsin. Science Signaling. 12. PMID 30890657 DOI: 10.1126/scisignal.aav4203  0.4
2019 Böhm M, Boness D, Fantisch E, Erhard H, Frauenholz J, Kowalzyk Z, Marcinkowski N, Kateriya S, Hegemann P, Kreimer G. Channelrhodopsin-1 phosphorylation changes with the phototactic behavior and responds to physiological stimuli in Chlamydomonas. The Plant Cell. PMID 30862615 DOI: 10.1105/tpc.18.00936  0.64
2019 Krause BS, Kaufmann JCD, Kuhne J, Vierock J, Huber T, Sakmar TP, Gerwert K, Bartl F, Hegemann P. Tracking pore hydration in channelrhodopsin by site-directed infrared-active azido probes. Biochemistry. PMID 30702875 DOI: 10.1021/acs.biochem.8b01211  0.44
2018 Oda K, Vierock J, Oishi S, Rodriguez-Rozada S, Taniguchi R, Yamashita K, Wiegert JS, Nishizawa T, Hegemann P, Nureki O. Crystal structure of the red light-activated channelrhodopsin Chrimson. Nature Communications. 9: 3949. PMID 30258177 DOI: 10.1038/s41467-018-06421-9  0.6
2018 Grimm C, Silapetere A, Vogt A, Bernal Sierra YA, Hegemann P. Electrical properties, substrate specificity and optogenetic potential of the engineered light-driven sodium pump eKR2. Scientific Reports. 8: 9316. PMID 29915394 DOI: 10.1038/s41598-018-27690-w  0.6
2018 Scheib U, Broser M, Constantin OM, Yang S, Gao S, Mukherjee S, Stehfest K, Nagel G, Gee CE, Hegemann P. Rhodopsin-cyclases for photocontrol of cGMP/cAMP and 2.3 Å structure of the adenylyl cyclase domain. Nature Communications. 9: 2046. PMID 29799525 DOI: 10.1038/s41467-018-04428-w  0.64
2018 Wietek J, Rodriguez-Rozada S, Tutas J, Tenedini F, Grimm C, Oertner TG, Soba P, Hegemann P, Wiegert JS. Author Correction: Anion-conducting channelrhodopsins with tuned spectra and modified kinetics engineered for optogenetic manipulation of behavior. Scientific Reports. 8: 4765. PMID 29540835 DOI: 10.1038/s41598-018-23001-5  0.64
2017 Hontani Y, Broser M, Silapetere A, Krause BS, Hegemann P, Kennis JTM. The femtosecond-to-second photochemistry of red-shifted fast-closing anion channelrhodopsin PsACR1. Physical Chemistry Chemical Physics : Pccp. PMID 29125160 DOI: 10.1039/c7cp06414d  0.44
2017 Wietek J, Rodriguez-Rozada S, Tutas J, Tenedini F, Grimm C, Oertner TG, Soba P, Hegemann P, Wiegert JS. Anion-conducting channelrhodopsins with tuned spectra and modified kinetics engineered for optogenetic manipulation of behavior. Scientific Reports. 7: 14957. PMID 29097684 DOI: 10.1038/s41598-017-14330-y  0.64
2017 Penzkofer A, Scheib U, Stehfest K, Hegemann P. Absorption and Emission Spectroscopic Investigation of Thermal Dynamics and Photo-Dynamics of the Rhodopsin Domain of the Rhodopsin-Guanylyl Cyclase from the Nematophagous Fungus Catenaria anguillulae. International Journal of Molecular Sciences. 18. PMID 28981475 DOI: 10.3390/ijms18102099  0.36
2017 Deisseroth K, Hegemann P. The form and function of channelrhodopsin. Science (New York, N.Y.). 357. PMID 28912215 DOI: 10.1126/science.aan5544  1
2017 Vierock J, Grimm C, Nitzan N, Hegemann P. Molecular determinants of proton selectivity and gating in the red-light activated channelrhodopsin Chrimson. Scientific Reports. 7: 9928. PMID 28855540 DOI: 10.1038/s41598-017-09600-8  0.6
2017 Hontani Y, Marazzi M, Stehfest K, Mathes T, van Stokkum IHM, Elstner M, Hegemann P, Kennis JTM. Reaction dynamics of the chimeric channelrhodopsin C1C2. Scientific Reports. 7: 7217. PMID 28775289 DOI: 10.1038/s41598-017-07363-w  0.44
2017 Kaufmann JCD, Krause BS, Grimm C, Ritter E, Hegemann P, Bartl FJ. Proton transfer reactions in the red light-activatable channelrhodopsin variant ReaChR and their relevance for its function. The Journal of Biological Chemistry. PMID 28659342 DOI: 10.1074/jbc.M117.779629  0.6
2017 Grimm C, Vierock J, Hegemann P, Wietek J. Whole-cell Patch-clamp Recordings for Electrophysiological Determination of Ion Selectivity in Channelrhodopsins. Journal of Visualized Experiments : Jove. PMID 28570519 DOI: 10.3791/55497  0.64
2017 Krause BS, Grimm C, Kaufmann JC, Schneider F, Sakmar TP, Bartl FJ, Hegemann P. Complex Photochemistry within the Green-Absorbing Channelrhodopsin ReaChR. Biophysical Journal. 112: 1166-1175. PMID 28355544 DOI: 10.1016/j.bpj.2017.02.001  0.6
2016 Guo Y, Beyle FE, Bold BM, Watanabe HC, Koslowski A, Thiel W, Hegemann P, Marazzi M, Elstner M. Active site structure and absorption spectrum of channelrhodopsin-2 wild-type and C128T mutant. Chemical Science. 7: 3879-3891. PMID 30155032 DOI: 10.1039/c6sc00468g  0.44
2016 Takahashi N, Oertner TG, Hegemann P, Larkum ME. Active cortical dendrites modulate perception. Science (New York, N.Y.). 354: 1587-1590. PMID 28008068 DOI: 10.1126/science.aah6066  0.64
2016 Ferenczi EA, Vierock J, Atsuta-Tsunoda K, Tsunoda SP, Ramakrishnan C, Gorini C, Thompson K, Lee SY, Berndt A, Perry C, Minniberger S, Vogt A, Mattis J, Prakash R, Delp S, ... ... Hegemann P, et al. Optogenetic approaches addressing extracellular modulation of neural excitability. Scientific Reports. 6: 23947. PMID 27045897 DOI: 10.1038/srep23947  1
2016 Wietek J, Broser M, Krause BS, Hegemann P. Identification of a Natural Green Light Absorbing Chloride Conducting Channelrhodopsin from Proteomonas sulcata. The Journal of Biological Chemistry. PMID 26740624 DOI: 10.1074/jbc.M115.699637  0.64
2015 Berndt A, Lee SY, Wietek J, Ramakrishnan C, Steinberg EE, Rashid AJ, Kim H, Park S, Santoro A, Frankland PW, Iyer SM, Pak S, Ährlund-Richter S, Delp SL, Malenka RC, ... ... Hegemann P, et al. Structural foundations of optogenetics: Determinants of channelrhodopsin ion selectivity. Proceedings of the National Academy of Sciences of the United States of America. PMID 26699459 DOI: 10.1073/pnas.1523341113  1
2015 Mehlhorn J, Lindtner T, Richter F, Glaß K, Steinocher H, Beck S, Hegemann P, Kennis JT, Mathes T. Light-Induced Rearrangement of the β5 Strand in the BLUF Photoreceptor SyPixD (Slr1694). The Journal of Physical Chemistry Letters. 6: 4749-53. PMID 26631358 DOI: 10.1021/acs.jpclett.5b02245  1
2015 Vogt A, Guo Y, Tsunoda SP, Kateriya S, Elstner M, Hegemann P. Conversion of a light-driven proton pump into a light-gated ion channel. Scientific Reports. 5: 16450. PMID 26597707 DOI: 10.1038/srep16450  1
2015 Rost BR, Schneider F, Grauel MK, Wozny C, G Bentz C, Blessing A, Rosenmund T, Jentsch TJ, Schmitz D, Hegemann P, Rosenmund C. Optogenetic acidification of synaptic vesicles and lysosomes. Nature Neuroscience. PMID 26551543 DOI: 10.1038/nn.4161  1
2015 Wietek J, Beltramo R, Scanziani M, Hegemann P, Oertner TG, Simon Wiegert J. An improved chloride-conducting channelrhodopsin for light-induced inhibition of neuronal activity in vivo. Scientific Reports. 5: 14807. PMID 26443033 DOI: 10.1038/srep14807  1
2015 Adamantidis A, Arber S, Bains JS, Bamberg E, Bonci A, Buzsáki G, Cardin JA, Costa RM, Dan Y, Goda Y, Graybiel AM, Häusser M, Hegemann P, Huguenard JR, Insel TR, et al. Optogenetics: 10 years after ChR2 in neurons--views from the community. Nature Neuroscience. 18: 1202-12. PMID 26308981 DOI: 10.1038/nn.4106  1
2015 Scheib U, Stehfest K, Gee CE, Körschen HG, Fudim R, Oertner TG, Hegemann P. The rhodopsin-guanylyl cyclase of the aquatic fungus Blastocladiella emersonii enables fast optical control of cGMP signaling. Science Signaling. 8: rs8. PMID 26268609 DOI: 10.1126/scisignal.aab0611  1
2015 Bruun S, Stoeppler D, Keidel A, Kuhlmann U, Luck M, Diehl A, Geiger MA, Woodmansee D, Trauner D, Hegemann P, Oschkinat H, Hildebrandt P, Stehfest K. Light-Dark Adaptation of Channelrhodopsin Involves Photoconversion between the all-trans and 13-cis Retinal Isomers. Biochemistry. 54: 5389-400. PMID 26237332 DOI: 10.1021/acs.biochem.5b00597  1
2015 Schneider F, Grimm C, Hegemann P. Biophysics of Channelrhodopsin. Annual Review of Biophysics. 44: 167-86. PMID 26098512 DOI: 10.1146/annurev-biophys-060414-034014  1
2015 Luck M, Bruun S, Keidel A, Hegemann P, Hildebrandt P. Photochemical chromophore isomerization in histidine kinase rhodopsin HKR1. Febs Letters. 589: 1067-71. PMID 25836735 DOI: 10.1016/j.febslet.2015.03.024  1
2015 AzimiHashemi N, Erbguth K, Vogt A, Riemensperger T, Rauch E, Woodmansee D, Nagpal J, Brauner M, Sheves M, Fiala A, Kattner L, Trauner D, Hegemann P, Gottschalk A, Liewald JF. Erratum: Synthetic retinal analogs modify the spectral and kinetic characteristics of microbial rhodopsin optogenetic tools. Nature Communications. 6: 6458. PMID 25711720 DOI: 10.1038/ncomms7458  0.4
2015 Jansen V, Alvarez L, Balbach M, Strünker T, Hegemann P, Kaupp UB, Wachten D. Controlling fertilization and cAMP signaling in sperm by optogenetics. Elife. 4. PMID 25601414 DOI: 10.7554/eLife.05161  1
2015 Kuhne J, Eisenhauer K, Ritter E, Hegemann P, Gerwert K, Bartl F. Early formation of the ion-conducting pore in channelrhodopsin-2. Angewandte Chemie (International Ed. in English). 54: 4953-7. PMID 25537168 DOI: 10.1002/anie.201410180  1
2015 Richter F, Scheib US, Mehlhorn J, Schubert R, Wietek J, Gernetzki O, Hegemann P, Mathes T, Möglich A. Upgrading a microplate reader for photobiology and all-optical experiments. Photochemical & Photobiological Sciences : Official Journal of the European Photochemistry Association and the European Society For Photobiology. 14: 270-9. PMID 25373866 DOI: 10.1039/c4pp00361f  1
2014 AzimiHashemi N, Erbguth K, Vogt A, Riemensperger T, Rauch E, Woodmansee D, Nagpal J, Brauner M, Sheves M, Fiala A, Kattner L, Trauner D, Hegemann P, Gottschalk A, Liewald JF. Synthetic retinal analogues modify the spectral and kinetic characteristics of microbial rhodopsin optogenetic tools. Nature Communications. 5: 5810. PMID 25503804 DOI: 10.1038/ncomms6810  1
2014 Penzkofer A, Stierl M, Mathes T, Hegemann P. Absorption and emission spectroscopic characterization of photo-dynamics of photoactivated adenylyl cyclase mutant bPAC-Y7F of Beggiatoa sp. Journal of Photochemistry and Photobiology. B, Biology. 140: 182-93. PMID 25154810 DOI: 10.1016/j.jphotobiol.2014.06.017  1
2014 Stierl M, Penzkofer A, Kennis JT, Hegemann P, Mathes T. Key residues for the light regulation of the blue light-activated adenylyl cyclase from Beggiatoa sp. Biochemistry. 53: 5121-30. PMID 25046330 DOI: 10.1021/bi500479v  1
2014 Wietek J, Wiegert JS, Adeishvili N, Schneider F, Watanabe H, Tsunoda SP, Vogt A, Elstner M, Oertner TG, Hegemann P. Conversion of channelrhodopsin into a light-gated chloride channel. Science (New York, N.Y.). 344: 409-12. PMID 24674867 DOI: 10.1126/science.1249375  1
2014 Penzkofer A, Luck M, Mathes T, Hegemann P. Bistable retinal schiff base photodynamics of histidine kinase rhodopsin HKR1 from Chlamydomonas reinhardtii. Photochemistry and Photobiology. 90: 773-85. PMID 24460585 DOI: 10.1111/php.12246  1
2014 Ernst OP, Lodowski DT, Elstner M, Hegemann P, Brown LS, Kandori H. Microbial and animal rhodopsins: structures, functions, and molecular mechanisms. Chemical Reviews. 114: 126-63. PMID 24364740 DOI: 10.1021/cr4003769  1
2014 Grote M, Engelhard M, Hegemann P. Of ion pumps, sensors and channels - perspectives on microbial rhodopsins between science and history. Biochimica Et Biophysica Acta. 1837: 533-45. PMID 23994288 DOI: 10.1016/j.bbabio.2013.08.006  1
2014 Schade U, Ritter E, Hegemann P, Aziz EF, Hofmann KP. Concept for a single-shot mid-infrared spectrometer using synchrotron radiation Vibrational Spectroscopy. 75: 190-195. DOI: 10.1016/j.vibspec.2014.07.004  1
2014 Penzkofer A, Tanwar M, Veetil SK, Kateriya S, Stierl M, Hegemann P. Photo-dynamics of BLUF domain containing adenylyl cyclase NgPAC3 from the amoeboflagellate Naegleria gruberi NEG-M strain Journal of Photochemistry and Photobiology a: Chemistry. 287: 19-29. DOI: 10.1016/j.jphotochem.2014.04.017  1
2013 Mehlhorn J, Steinocher H, Beck S, Kennis JT, Hegemann P, Mathes T. A set of engineered Escherichia coli expression strains for selective isotope and reactivity labeling of amino acid side chains and flavin cofactors. Plos One. 8: e79006. PMID 24223875 DOI: 10.1371/journal.pone.0079006  1
2013 Vogt A, Wietek J, Hegemann P. Gloeobacter rhodopsin, limitation of proton pumping at high electrochemical load. Biophysical Journal. 105: 2055-63. PMID 24209850 DOI: 10.1016/j.bpj.2013.08.031  1
2013 Möglich A, Hegemann P. Biotechnology: Programming genomes with light. Nature. 500: 406-8. PMID 23969454 DOI: 10.1038/500406a  1
2013 Schneider F, Gradmann D, Hegemann P. Ion selectivity and competition in channelrhodopsins. Biophysical Journal. 105: 91-100. PMID 23823227 DOI: 10.1016/j.bpj.2013.05.042  1
2013 Hartmann A, Arroyo-Olarte RD, Imkeller K, Hegemann P, Lucius R, Gupta N. Optogenetic modulation of an adenylate cyclase in Toxoplasma gondii demonstrates a requirement of the parasite cAMP for host-cell invasion and stage differentiation. The Journal of Biological Chemistry. 288: 13705-17. PMID 23525100 DOI: 10.1074/jbc.M113.465583  1
2013 Yawo H, Koizumi A, Hegemann P. Adventure beyond borders of scientific fields with optogenetics. Neuroscience Research. 75: 1-2. PMID 23465316 DOI: 10.1016/j.neures.2013.02.001  1
2013 Akerboom J, Carreras Calderón N, Tian L, Wabnig S, Prigge M, Tolö J, Gordus A, Orger MB, Severi KE, Macklin JJ, Patel R, Pulver SR, Wardill TJ, Fischer E, Schüler C, ... ... Hegemann P, et al. Genetically encoded calcium indicators for multi-color neural activity imaging and combination with optogenetics. Frontiers in Molecular Neuroscience. 6: 2. PMID 23459413 DOI: 10.3389/fnmol.2013.00002  1
2013 Ritter E, Piwowarski P, Hegemann P, Bartl FJ. Light-dark adaptation of channelrhodopsin C128T mutant. The Journal of Biological Chemistry. 288: 10451-8. PMID 23439646 DOI: 10.1074/jbc.M112.446427  1
2013 Watanabe HC, Welke K, Sindhikara DJ, Hegemann P, Elstner M. Towards an understanding of channelrhodopsin function: simulations lead to novel insights of the channel mechanism. Journal of Molecular Biology. 425: 1795-814. PMID 23376098 DOI: 10.1016/j.jmb.2013.01.033  1
2013 Clarke M, Lohan AJ, Liu B, Lagkouvardos I, Roy S, Zafar N, Bertelli C, Schilde C, Kianianmomeni A, Bürglin TR, Frech C, Turcotte B, Kopec KO, Synnott JM, Choo C, ... ... Hegemann P, et al. Genome of Acanthamoeba castellanii highlights extensive lateral gene transfer and early evolution of tyrosine kinase signaling. Genome Biology. 14: R11. PMID 23375108 DOI: 10.1186/gb-2013-14-2-r11  1
2013 Hegemann P, Nagel G. From channelrhodopsins to optogenetics. Embo Molecular Medicine. 5: 173-6. PMID 23339069 DOI: 10.1002/emmm.201202387  1
2013 Sizova I, Greiner A, Awasthi M, Kateriya S, Hegemann P. Nuclear gene targeting in Chlamydomonas using engineered zinc-finger nucleases. The Plant Journal : For Cell and Molecular Biology. 73: 873-82. PMID 23137232 DOI: 10.1111/tpj.12066  1
2013 Penzkofer A, Tanwar M, Veetil SK, Kateriya S, Stierl M, Hegemann P. Photo-dynamics of the lyophilized photo-activated adenylate cyclase NgPAC2 from the amoeboflagellate Naegleria gruberi NEG-M strain Chemical Physics. 423: 192-201. DOI: 10.1016/j.chemphys.2013.07.001  1
2013 Penzkofer A, Tanwar M, Veetil SK, Kateriya S, Stierl M, Hegemann P. Photo-dynamics and thermal behavior of the BLUF domain containing adenylate cyclase NgPAC2 from the amoeboflagellate Naegleria gruberi NEG-M strain Chemical Physics. 412: 96-108. DOI: 10.1016/j.chemphys.2012.12.015  1
2012 Trippens J, Greiner A, Schellwat J, Neukam M, Rottmann T, Lu Y, Kateriya S, Hegemann P, Kreimer G. Phototropin influence on eyespot development and regulation of phototactic behavior in Chlamydomonas reinhardtii. The Plant Cell. 24: 4687-702. PMID 23204408 DOI: 10.1105/tpc.112.103523  1
2012 Erbguth K, Prigge M, Schneider F, Hegemann P, Gottschalk A. Bimodal activation of different neuron classes with the spectrally red-shifted channelrhodopsin chimera C1V1 in Caenorhabditis elegans. Plos One. 7: e46827. PMID 23056472 DOI: 10.1371/journal.pone.0046827  1
2012 Luck M, Mathes T, Bruun S, Fudim R, Hagedorn R, Tran Nguyen TM, Kateriya S, Kennis JT, Hildebrandt P, Hegemann P. A photochromic histidine kinase rhodopsin (HKR1) that is bimodally switched by ultraviolet and blue light. The Journal of Biological Chemistry. 287: 40083-90. PMID 23027869 DOI: 10.1074/jbc.M112.401604  1
2012 Prigge M, Schneider F, Tsunoda SP, Shilyansky C, Wietek J, Deisseroth K, Hegemann P. Color-tuned channelrhodopsins for multiwavelength optogenetics. The Journal of Biological Chemistry. 287: 31804-12. PMID 22843694 DOI: 10.1074/jbc.M112.391185  1
2012 Kato HE, Zhang F, Yizhar O, Ramakrishnan C, Nishizawa T, Hirata K, Ito J, Aita Y, Tsukazaki T, Hayashi S, Hegemann P, Maturana AD, Ishitani R, Deisseroth K, Nureki O. Crystal structure of the channelrhodopsin light-gated cation channel. Nature. 482: 369-74. PMID 22266941 DOI: 10.1038/nature10870  1
2012 Watanabe HC, Welke K, Schneider F, Tsunoda S, Zhang F, Deisseroth K, Hegemann P, Elstner M. Structural model of channelrhodopsin. The Journal of Biological Chemistry. 287: 7456-66. PMID 22241469 DOI: 10.1074/jbc.M111.320309  1
2012 Eisenhauer K, Kuhne J, Ritter E, Berndt A, Wolf S, Freier E, Bartl F, Hegemann P, Gerwert K. In channelrhodopsin-2 Glu-90 is crucial for ion selectivity and is deprotonated during the photocycle. The Journal of Biological Chemistry. 287: 6904-11. PMID 22219197 DOI: 10.1074/jbc.M111.327700  1
2012 Mathes T, Zhu J, Van Stokkum IHM, Groot ML, Hegemann P, Kennis JTM. Hydrogen bond switching among flavin and amino acids determines the nature of proton-coupled electron transfer in bluf photoreceptors Journal of Physical Chemistry Letters. 3: 203-208. DOI: 10.1021/jz201579y  1
2012 Penzkofer A, Stierl M, Hegemann P, Kateriya S. Absorption and fluorescence characteristics of photo-activated adenylate cyclase nano-clusters from the amoeboflagellate Naegleria gruberi NEG-M strain Chemical Physics. 392: 46-54. DOI: 10.1016/j.chemphys.2011.09.005  1
2011 Zhang F, Vierock J, Yizhar O, Fenno LE, Tsunoda S, Kianianmomeni A, Prigge M, Berndt A, Cushman J, Polle J, Magnuson J, Hegemann P, Deisseroth K. The microbial opsin family of optogenetic tools. Cell. 147: 1446-57. PMID 22196724 DOI: 10.1016/j.cell.2011.12.004  1
2011 Bruun S, Naumann H, Kuhlmann U, Schulz C, Stehfest K, Hegemann P, Hildebrandt P. The chromophore structure of the long-lived intermediate of the C128T channelrhodopsin-2 variant. Febs Letters. 585: 3998-4001. PMID 22094167 DOI: 10.1016/j.febslet.2011.11.007  1
2011 Welke K, Frähmcke JS, Watanabe HC, Hegemann P, Elstner M. Color tuning in binding pocket models of the chlamydomonas-type channelrhodopsins. The Journal of Physical Chemistry. B. 115: 15119-28. PMID 22077286 DOI: 10.1021/jp2085457  1
2011 Gradmann D, Berndt A, Schneider F, Hegemann P. Rectification of the channelrhodopsin early conductance. Biophysical Journal. 101: 1057-68. PMID 21889442 DOI: 10.1016/j.bpj.2011.07.040  1
2011 Yizhar O, Fenno LE, Prigge M, Schneider F, Davidson TJ, O'Shea DJ, Sohal VS, Goshen I, Finkelstein J, Paz JT, Stehfest K, Fudim R, Ramakrishnan C, Huguenard JR, Hegemann P, et al. Neocortical excitation/inhibition balance in information processing and social dysfunction. Nature. 477: 171-8. PMID 21796121 DOI: 10.1038/nature10360  1
2011 Mathes T, van Stokkum IH, Bonetti C, Hegemann P, Kennis JT. The hydrogen-bond switch reaction of the Blrb Bluf domain of Rhodobacter sphaeroides. The Journal of Physical Chemistry. B. 115: 7963-71. PMID 21627064 DOI: 10.1021/jp201296m  1
2011 Gärtner W, Hegemann P. Introduction to the Symposium-in Print: Blue light effects. Photochemistry and Photobiology. 87: 489-90. PMID 21517885 DOI: 10.1111/j.1751-1097.2011.00926.x  1
2011 Berndt A, Schoenenberger P, Mattis J, Tye KM, Deisseroth K, Hegemann P, Oertner TG. High-efficiency channelrhodopsins for fast neuronal stimulation at low light levels. Proceedings of the National Academy of Sciences of the United States of America. 108: 7595-600. PMID 21504945 DOI: 10.1073/pnas.1017210108  1
2011 Yizhar O, Fenno L, Zhang F, Hegemann P, Diesseroth K. Microbial opsins: a family of single-component tools for optical control of neural activity. Cold Spring Harbor Protocols. 2011: top102. PMID 21363959 DOI: 10.1101/pdb.top102  1
2011 Weber S, Schroeder C, Kacprzak S, Mathes T, Kowalczyk RM, Essen LO, Hegemann P, Schleicher E, Bittl R. Light-generated paramagnetic intermediates in BLUF domains. Photochemistry and Photobiology. 87: 574-83. PMID 21198648 DOI: 10.1111/j.1751-1097.2010.00885.x  1
2011 Hegemann P, Möglich A. Channelrhodopsin engineering and exploration of new optogenetic tools. Nature Methods. 8: 39-42. PMID 21191371 DOI: 10.1038/nmeth.f.327  1
2011 Stierl M, Stumpf P, Udwari D, Gueta R, Hagedorn R, Losi A, Gärtner W, Petereit L, Efetova M, Schwarzel M, Oertner TG, Nagel G, Hegemann P. Light modulation of cellular cAMP by a small bacterial photoactivated adenylyl cyclase, bPAC, of the soil bacterium Beggiatoa. The Journal of Biological Chemistry. 286: 1181-8. PMID 21030594 DOI: 10.1074/jbc.M110.185496  1
2011 Tyagi A, Penzkofer A, Mathes T, Hegemann P. Photo-cycle dynamics of LOV1-His domain of phototropin from chlamydomonas reinhardtii with roseoflavin monophosphate cofactor Proceedings of Spie - the International Society For Optical Engineering. 7993. DOI: 10.1117/12.879134  1
2011 Penzkofer A, Stierl M, Hegemann P, Kateriya S. Thermal protein unfolding in photo-activated adenylate cyclase nano-clusters from the amoeboflagellate Naegleria gruberi NEG-M strain Journal of Photochemistry and Photobiology a: Chemistry. 225: 42-51. DOI: 10.1016/j.jphotochem.2011.09.024  1
2011 Penzkofer A, Stierl M, Hegemann P, Kateriya S. Photo-dynamics of the BLUF domain containing soluble adenylate cyclase (nPAC) from the amoeboflagellate Naegleria gruberi NEG-M strain Chemical Physics. 387: 25-38. DOI: 10.1016/j.chemphys.2011.05.028  1
2010 Prigge M, Rösler A, Hegemann P. Fast, repetitive light-activation of CaV3.2 using channelrhodopsin 2. Channels (Austin, Tex.). 4: 241-7. PMID 20714225  1
2010 Tyagi A, Penzkofer A, Mathes T, Hegemann P. Photophysical characterisation and photo-cycle dynamics of LOV1-His domain of phototropin from Chlamydomonas reinhardtii with roseoflavin monophosphate cofactor. Journal of Photochemistry and Photobiology. B, Biology. 101: 76-88. PMID 20655238 DOI: 10.1016/j.jphotobiol.2010.06.014  1
2010 Brosi R, Illarionov B, Mathes T, Fischer M, Joshi M, Bacher A, Hegemann P, Bittl R, Weber S, Schleicher E. Hindered rotation of a cofactor methyl group as a probe for protein-cofactor interaction. Journal of the American Chemical Society. 132: 8935-44. PMID 20536240 DOI: 10.1021/ja910681z  1
2010 Stehfest K, Hegemann P. Evolution of the channelrhodopsin photocycle model. Chemphyschem : a European Journal of Chemical Physics and Physical Chemistry. 11: 1120-6. PMID 20349494 DOI: 10.1002/cphc.200900980  1
2010 Stehfest K, Ritter E, Berndt A, Bartl F, Hegemann P. The branched photocycle of the slow-cycling channelrhodopsin-2 mutant C128T. Journal of Molecular Biology. 398: 690-702. PMID 20346954 DOI: 10.1016/j.jmb.2010.03.031  1
2010 Berndt A, Prigge M, Gradmann D, Hegemann P. Two open states with progressive proton selectivities in the branched channelrhodopsin-2 photocycle. Biophysical Journal. 98: 753-61. PMID 20197028 DOI: 10.1016/j.bpj.2009.10.052  1
2010 Gunaydin LA, Yizhar O, Berndt A, Sohal VS, Deisseroth K, Hegemann P. Ultrafast optogenetic control. Nature Neuroscience. 13: 387-92. PMID 20081849 DOI: 10.1038/nn.2495  1
2010 Pfeifer A, Mathes T, Lu Y, Hegemann P, Kottke T. Blue light induces global and localized conformational changes in the kinase domain of full-length phototropin. Biochemistry. 49: 1024-32. PMID 20052995 DOI: 10.1021/bi9016044  1
2010 Tyagi A, Penzkofer A, Mathes T, Hegemann P. Photo-degradation behaviour of roseoflavin in some aqueous solutions Chemical Physics. 369: 27-36. DOI: 10.1016/j.chemphys.2010.02.004  1
2009 Bonetti C, Stierl M, Mathes T, van Stokkum IH, Mullen KM, Cohen-Stuart TA, van Grondelle R, Hegemann P, Kennis JT. The role of key amino acids in the photoactivation pathway of the Synechocystis Slr1694 BLUF domain. Biochemistry. 48: 11458-69. PMID 19863128 DOI: 10.1021/bi901196x  1
2009 Zirak P, Penzkofer A, Mathes T, Hegemann P. Absorption and emission spectroscopic characterization of BLUF protein Slr1694 from Synechocystis sp. PCC6803 with roseoflavin cofactor. Journal of Photochemistry and Photobiology. B, Biology. 97: 61-70. PMID 19758819 DOI: 10.1016/j.jphotobiol.2009.08.002  1
2009 Looser J, Schröder-Lang S, Hegemann P, Nagel G. Mechanistic insights in light-induced cAMP production by photoactivated adenylyl cyclase alpha (PACalpha). Biological Chemistry. 390: 1105-11. PMID 19747080 DOI: 10.1515/BC.2009.132  1
2009 Kianianmomeni A, Stehfest K, Nematollahi G, Hegemann P, Hallmann A. Channelrhodopsins of Volvox carteri are photochromic proteins that are specifically expressed in somatic cells under control of light, temperature, and the sex inducer. Plant Physiology. 151: 347-66. PMID 19641026 DOI: 10.1104/pp.109.143297  1
2009 Tsunoda SP, Hegemann P. Glu 87 of channelrhodopsin-1 causes pH-dependent color tuning and fast photocurrent inactivation. Photochemistry and Photobiology. 85: 564-9. PMID 19192197 DOI: 10.1111/j.1751-1097.2008.00519.x  1
2009 Zorin B, Lu Y, Sizova I, Hegemann P. Nuclear gene targeting in Chlamydomonas as exemplified by disruption of the PHOT gene. Gene. 432: 91-6. PMID 19121376 DOI: 10.1016/j.gene.2008.11.028  1
2009 Berndt A, Yizhar O, Gunaydin LA, Hegemann P, Deisseroth K. Bi-stable neural state switches. Nature Neuroscience. 12: 229-34. PMID 19079251 DOI: 10.1038/nn.2247  1
2009 Mathes T, Vogl C, Stolz J, Hegemann P. In vivo generation of flavoproteins with modified cofactors. Journal of Molecular Biology. 385: 1511-8. PMID 19027027 DOI: 10.1016/j.jmb.2008.11.001  1
2009 Tyagi A, Zirak P, Penzkofer A, Mathes T, Hegemann P, Mack M, Ghisla S. Absorption and emission spectroscopic characterisation of 8-amino-riboflavin Chemical Physics. 364: 19-30. DOI: 10.1016/j.chemphys.2009.08.005  1
2009 Zirak P, Penzkofer A, Mathes T, Hegemann P. Photo-dynamics of roseoflavin and riboflavin in aqueous and organic solvents Chemical Physics. 358: 111-122. DOI: 10.1016/j.chemphys.2008.12.026  1
2009 Hegemann P, Berthold P. Sensory Photoreceptors and Light Control of Flagellar Activity The Chlamydomonas Sourcebook 3-Vol Set. 3: 395-429. DOI: 10.1016/B978-0-12-370873-1.00050-2  1
2008 Ritter E, Stehfest K, Berndt A, Hegemann P, Bartl FJ. Monitoring light-induced structural changes of Channelrhodopsin-2 by UV-visible and Fourier transform infrared spectroscopy. The Journal of Biological Chemistry. 283: 35033-41. PMID 18927082 DOI: 10.1074/jbc.M806353200  1
2008 Bonetti C, Mathes T, van Stokkum IH, Mullen KM, Groot ML, van Grondelle R, Hegemann P, Kennis JT. Hydrogen bond switching among flavin and amino acid side chains in the BLUF photoreceptor observed by ultrafast infrared spectroscopy. Biophysical Journal. 95: 4790-802. PMID 18708458 DOI: 10.1529/biophysj.108.139246  1
2008 Hagedorn R, Gradmann D, Hegemann P. Dynamics of voltage profile in enzymatic ion transporters, demonstrated in electrokinetics of proton pumping rhodopsin. Biophysical Journal. 95: 5005-13. PMID 18621842 DOI: 10.1529/biophysj.107.125260  1
2008 Berthold P, Tsunoda SP, Ernst OP, Mages W, Gradmann D, Hegemann P. Channelrhodopsin-1 initiates phototaxis and photophobic responses in chlamydomonas by immediate light-induced depolarization. The Plant Cell. 20: 1665-77. PMID 18552201 DOI: 10.1105/tpc.108.057919  0.76
2008 Hegemann P. Algal sensory photoreceptors. Annual Review of Plant Biology. 59: 167-89. PMID 18444900 DOI: 10.1146/annurev.arplant.59.032607.092847  1
2008 Zhang F, Prigge M, Beyrière F, Tsunoda SP, Mattis J, Yizhar O, Hegemann P, Deisseroth K. Red-shifted optogenetic excitation: a tool for fast neural control derived from Volvox carteri. Nature Neuroscience. 11: 631-3. PMID 18432196 DOI: 10.1038/nn.2120  1
2008 Ernst OP, Sánchez Murcia PA, Daldrop P, Tsunoda SP, Kateriya S, Hegemann P. Photoactivation of channelrhodopsin. The Journal of Biological Chemistry. 283: 1637-43. PMID 17993465 DOI: 10.1074/jbc.M708039200  1
2007 Nöll G, Hauska G, Hegemann P, Lanzl K, Nöll T, von Sanden-Flohe M, Dick B. Redox properties of LOV domains: chemical versus photochemical reduction, and influence on the photocycle. Chembiochem : a European Journal of Chemical Biology. 8: 2256-64. PMID 17990262 DOI: 10.1002/cbic.200700304  1
2007 Song SH, Dick B, Penzkofer A, Hegemann P. Photo-reduction of flavin mononucleotide to semiquinone form in LOV domain mutants of blue-light receptor phot from Chlamydomonas reinhardtii. Journal of Photochemistry and Photobiology. B, Biology. 87: 37-48. PMID 17292618 DOI: 10.1016/j.jphotobiol.2006.12.007  1
2007 Schröder-Lang S, Schwärzel M, Seifert R, Strünker T, Kateriya S, Looser J, Watanabe M, Kaupp UB, Hegemann P, Nagel G. Fast manipulation of cellular cAMP level by light in vivo. Nature Methods. 4: 39-42. PMID 17128267 DOI: 10.1038/nmeth975  1
2007 Zirak P, Penzkofer A, Lehmpfuhl C, Mathes T, Hegemann P. Absorption and emission spectroscopic characterization of blue-light receptor Slr1694 from Synechocystis sp. PCC6803. Journal of Photochemistry and Photobiology. B, Biology. 86: 22-34. PMID 16996275 DOI: 10.1016/j.jphotobiol.2006.08.007  1
2007 Zirak P, Penzkofer A, Hegemann P, Mathes T. Photo dynamics of BLUF domain mutant H44R of AppA from Rhodobacter sphaeroides Chemical Physics. 335: 15-27. DOI: 10.1016/j.chemphys.2007.03.013  1
2006 Gauden M, van Stokkum IH, Key JM, Lührs DCh, van Grondelle R, Hegemann P, Kennis JT. Hydrogen-bond switching through a radical pair mechanism in a flavin-binding photoreceptor. Proceedings of the National Academy of Sciences of the United States of America. 103: 10895-900. PMID 16829579 DOI: 10.1073/pnas.0600720103  1
2006 Tsunoda SP, Ewers D, Gazzarrini S, Moroni A, Gradmann D, Hegemann P. H+ -pumping rhodopsin from the marine alga Acetabularia. Biophysical Journal. 91: 1471-9. PMID 16731558 DOI: 10.1529/biophysj.106.086421  1
2006 Kottke T, Hegemann P, Dick B, Heberle J. The photochemistry of the light-, oxygen-, and voltage-sensitive domains in the algal blue light receptor phot. Biopolymers. 82: 373-8. PMID 16552739 DOI: 10.1002/bip.20510  1
2006 Zirak P, Penzkofer A, Schiereis T, Hegemann P, Jung A, Schlichting I. Photodynamics of the small BLUF protein BlrB from Rhodobacter sphaeroides. Journal of Photochemistry and Photobiology. B, Biology. 83: 180-94. PMID 16495071 DOI: 10.1016/j.jphotobiol.2005.12.015  1
2006 Gauden M, Laan W, Key JM, van Stokkum IHM, van Grondelle R, Hellingwerf KJ, Hegemann P, Kennis JTM. The photochemistry of novel flavin-binding photoreceptors Femtochemistry Vii. 321-330. DOI: 10.1016/B978-044452821-6/50046-0  1
2006 Schnegg A, Okafuji A, Bacher A, Bittl R, Fischer M, Fuchs MR, Hegemann P, Joshi M, Kay CWM, Richter G, Schleicher E, Weber S. Towards an identification of chemically different flavin radicals by means of their g-tensor Applied Magnetic Resonance. 30: 345-358.  1
2005 Li X, Gutierrez DV, Hanson MG, Han J, Mark MD, Chiel H, Hegemann P, Landmesser LT, Herlitze S. Fast noninvasive activation and inhibition of neural and network activity by vertebrate rhodopsin and green algae channelrhodopsin. Proceedings of the National Academy of Sciences of the United States of America. 102: 17816-21. PMID 16306259 DOI: 10.1073/pnas.0509030102  1
2005 Hegemann P, Ehlenbeck S, Gradmann D. Multiple photocycles of channelrhodopsin. Biophysical Journal. 89: 3911-8. PMID 16169986 DOI: 10.1529/biophysj.105.069716  1
2005 Song SH, Dick B, Zirak P, Penzkofer A, Schiereis T, Hegemann P. Absorption and emission spectroscopic characterisation of combined wildtype LOV1-LOV2 domain of phot from Chlamydomonas reinhardtii. Journal of Photochemistry and Photobiology. B, Biology. 81: 55-65. PMID 16111889 DOI: 10.1016/j.jphotobiol.2005.06.003  1
2005 Nagel G, Szellas T, Kateriya S, Adeishvili N, Hegemann P, Bamberg E. Channelrhodopsins: directly light-gated cation channels. Biochemical Society Transactions. 33: 863-6. PMID 16042615 DOI: 10.1042/BST0330863  1
2005 Zorin B, Hegemann P, Sizova I. Nuclear-gene targeting by using single-stranded DNA avoids illegitimate DNA integration in Chlamydomonas reinhardtii. Eukaryotic Cell. 4: 1264-72. PMID 16002652 DOI: 10.1128/EC.4.7.1264-1272.2005  1
2005 Guo H, Kottke T, Hegemann P, Dick B. The phot LOV2 domain and its interaction with LOV1. Biophysical Journal. 89: 402-12. PMID 15879473 DOI: 10.1529/biophysj.104.058230  1
2005 Fuhrmann M, Oertel W, Berthold P, Hegemann P. Removal of mismatched bases from synthetic genes by enzymatic mismatch cleavage. Nucleic Acids Research. 33: e58. PMID 15800209 DOI: 10.1093/nar/gni058  1
2005 Shalguev VI, Kaboev OK, Sizova IA, Hegemann P, Lantsov VA. [Identification of Rad51 protein from Chlamydomonas reinhardtii: recombinational characteristics]. Molekuliarnaia Biologiia. 39: 112-9. PMID 15773555  1
2005 Holzer W, Penzkofer A, Hegemann P. Photopysical and photochemical excitation and relaxation dynamics of LOV domains of phot from Chlamydomonas reinhardtii Journal of Luminescence. 112: 444-448. DOI: 10.1016/j.jlumin.2004.09.069  1
2005 Penzkofer A, Endres L, Schiereis T, Hegemann P. Yield of photo-adduct formation of LOV domains from Chlamydomonas reinhardtii by picosecond laser excitation Chemical Physics. 316: 185-194. DOI: 10.1016/j.chemphys.2005.05.016  1
2005 Zirak P, Penzkofer A, Schiereis T, Hegemann P, Jung A, Schlichting I. Absorption and fluorescence spectroscopic characterization of BLUF domain of AppA from Rhodobacter sphaeroides Chemical Physics. 315: 142-154. DOI: 10.1016/j.chemphys.2005.04.008  1
2005 Holzer W, Penzkofer A, Hegemann P. Absorption and emission spectroscopic characterisation of the LOV2-His domain of phot from Chlamydomonas reinhardtii Chemical Physics. 308: 79-91. DOI: 10.1016/j.chemphys.2004.08.007  1
2005 Holzer W, Shirdel J, Zirak P, Penzkofer A, Hegemann P, Deutzmann R, Hochmuth E. Photo-induced degradation of some flavins in aqueous solution Chemical Physics. 308: 69-78. DOI: 10.1016/j.chemphys.2004.08.006  1
2004 Fuhrmann M, Hausherr A, Ferbitz L, Schödl T, Heitzer M, Hegemann P. Monitoring dynamic expression of nuclear genes in Chlamydomonas reinhardtii by using a synthetic luciferase reporter gene. Plant Molecular Biology. 55: 869-81. PMID 15604722 DOI: 10.1007/s11103-004-2150-6  1
2004 Schleicher E, Kowalczyk RM, Kay CW, Hegemann P, Bacher A, Fischer M, Bittl R, Richter G, Weber S. On the reaction mechanism of adduct formation in LOV domains of the plant blue-light receptor phototropin. Journal of the American Chemical Society. 126: 11067-76. PMID 15339193 DOI: 10.1021/ja049553q  1
2004 Bednarz T, Losi A, Gartner W, Hegemann P, Heberle J. Functional variations among LOV domains as revealed by FT-IR difference spectroscopy. Photochemical & Photobiological Sciences : Official Journal of the European Photochemistry Association and the European Society For Photobiology. 3: 575-9. PMID 15170487 DOI: 10.1039/b400976b  1
2004 Kateriya S, Nagel G, Bamberg E, Hegemann P. "Vision" in single-celled algae. News in Physiological Sciences : An International Journal of Physiology Produced Jointly by the International Union of Physiological Sciences and the American Physiological Society. 19: 133-7. PMID 15143209 DOI: 10.1152/nips.01517.2004  1
2004 Losi A, Kottke T, Hegemann P. Recording of blue light-induced energy and volume changes within the wild-type and mutated phot-LOV1 domain from Chlamydomonas reinhardtii. Biophysical Journal. 86: 1051-60. PMID 14747340 DOI: 10.1016/S0006-3495(04)74180-6  1
2004 Holzer W, Penzkofer A, Susdorf T, Álvarez M, Islam SDM, Hegemann P. Absorption and emission spectroscopic characterisation of the LOV2-domain of phot from Chlamydomonas reinhardtii fused to a maltose binding protein Chemical Physics. 302: 105-118. DOI: 10.1016/j.chemphys.2004.03.017  1
2003 Nagel G, Szellas T, Huhn W, Kateriya S, Adeishvili N, Berthold P, Ollig D, Hegemann P, Bamberg E. Channelrhodopsin-2, a directly light-gated cation-selective membrane channel. Proceedings of the National Academy of Sciences of the United States of America. 100: 13940-5. PMID 14615590 DOI: 10.1073/pnas.1936192100  1
2003 Kottke T, Dick B, Fedorov R, Schlichting I, Deutzmann R, Hegemann P. Irreversible photoreduction of flavin in a mutated Phot-LOV1 domain. Biochemistry. 42: 9854-62. PMID 12924934 DOI: 10.1021/bi034863r  1
2003 Bittl R, Kay CW, Weber S, Hegemann P. Characterization of a flavin radical product in a C57M mutant of a LOV1 domain by electron paramagnetic resonance. Biochemistry. 42: 8506-12. PMID 12859197 DOI: 10.1021/bi034123i  1
2003 Fedorov R, Schlichting I, Hartmann E, Domratcheva T, Fuhrmann M, Hegemann P. Crystal structures and molecular mechanism of a light-induced signaling switch: The Phot-LOV1 domain from Chlamydomonas reinhardtii. Biophysical Journal. 84: 2474-82. PMID 12668455 DOI: 10.1016/S0006-3495(03)75052-8  1
2003 Ataka K, Hegemann P, Heberle J. Vibrational spectroscopy of an algal Phot-LOV1 domain probes the molecular changes associated with blue-light reception. Biophysical Journal. 84: 466-74. PMID 12524299 DOI: 10.1016/S0006-3495(03)74866-8  1
2003 Wrobel N, Deininger W, Hegemann P, Mirsky VM. Covalent immobilization of oligonucleotides on electrodes Colloids and Surfaces B: Biointerfaces. 32: 157-162. DOI: 10.1016/S0927-7765(03)00155-3  1
2003 Islam SDM, Penzkofer A, Hegemann P. Quantum yield of triplet formation of riboflavin in aqueous solution and of flavin mononucleotide bound to the LOV1 domain of Phot1 from Chlamydomonas reinhardtii Chemical Physics. 291: 97-114. DOI: 10.1016/S0301-0104(03)00187-3  1
2003 Drössler P, Holzer W, Penzkofer A, Hegemann P. Fluoresence quenching of riboflavin in aqueous solution by methionin and cystein Chemical Physics. 286: 409-420. DOI: 10.1016/S0301-0104(02)00969-2  1
2003 Islam SDM, Susdorf T, Penzkofer A, Hegemann P. Fluorescence quenching of flavin adenine dinucleotide in aqueous solution by pH dependent isomerisation and photo-induced electron transfer Chemical Physics. 295: 137-149. DOI: 10.1016/j.chemphys.2003.08.013  1
2002 Gradmann D, Ehlenbeck S, Hegemann P. Modeling light-induced currents in the eye of Chlamydomonas reinhardtii. The Journal of Membrane Biology. 189: 93-104. PMID 12235485 DOI: 10.1007/s00232-002-1006-8  1
2002 Nagel G, Ollig D, Fuhrmann M, Kateriya S, Musti AM, Bamberg E, Hegemann P. Channelrhodopsin-1: a light-gated proton channel in green algae. Science (New York, N.Y.). 296: 2395-8. PMID 12089443 DOI: 10.1126/science.1072068  1
2002 Holzer W, Penzkofer A, Fuhrmann M, Hegemann P. Spectroscopic characterization of flavin mononucleotide bound to the LOV1 domain of Phot1 from Chlamydomonas reinhardtii. Photochemistry and Photobiology. 75: 479-87. PMID 12017473 DOI: 10.1562/0031-8655(2002)075<0479:SCOFMB>2.0.CO;2  1
2002 Sizova IA, Hegemann P, Furmann M, Danilenko VN. [Streptomyces rimosus aminoglycoside-3'-phosphotransferase VIII: comparisons with aminoglycoside-3'-phosphotransferases of aminoglycoside-producing strains with eukaryotic protein kinases]. Molekuliarnaia Biologiia. 36: 27-36. PMID 11862708  1
2002 Ehlenbeck S, Gradmann D, Braun FJ, Hegemann P. Evidence for a light-induced H(+) conductance in the eye of the green alga Chlamydomonas reinhardtii. Biophysical Journal. 82: 740-51. PMID 11806916 DOI: 10.1016/S0006-3495(02)75436-2  1
2002 Sizova IA, Hegemann P, Furmann M, Danilenko VN. Streptomyces rimosus aminoglycoside 3′-phosphotransferase VIII: Comparisons with aminoglycoside 3′-phosphotransferases of aminoglycoside-producing strains and with eukaryotic protein kinases Molecular Biology. 36: 18-25. DOI: 10.1023/A:1014282003679  1
2002 Drössler P, Holzer W, Penzkofer A, Hegemann P. pH dependence of the absorption and emission behaviour of riboflavin in aqueous solution Chemical Physics. 282: 429-439. DOI: 10.1016/S0301-0104(02)00731-0  1
2001 Fuhrmann M, Stahlberg A, Govorunova E, Rank S, Hegemann P. The abundant retinal protein of the Chlamydomonas eye is not the photoreceptor for phototaxis and photophobic responses. Journal of Cell Science. 114: 3857-63. PMID 11719552  1
2001 Govorunova EG, Sineshchekov OA, Gärtner W, Chunaev AS, Hegemann P. Photoreceptor current and photoorientation in chlamydomonas mediated by 9-demethylchlamyrhodopsin. Biophysical Journal. 81: 2897-907. PMID 11606300 DOI: 10.1016/S0006-3495(01)75930-9  1
2001 Sizova I, Fuhrmann M, Hegemann P. A Streptomyces rimosus aphVIII gene coding for a new type phosphotransferase provides stable antibiotic resistance to Chlamydomonas reinhardtii. Gene. 277: 221-9. PMID 11602359 DOI: 10.1016/S0378-1119(01)00616-3  1
2001 Hegemann P, Deininger W. Chapter 8 Algal eyes and their rhodopsin photoreceptors Comprehensive Series in Photosciences. 1: 229-243. DOI: 10.1016/S1568-461X(01)80012-0  1
2000 Deininger W, Fuhrmann M, Hegemann P. Opsin evolution: out of wild green yonder? Trends in Genetics : Tig. 16: 158-9. PMID 10729830 DOI: 10.1016/S0168-9525(99)01959-9  1
1999 Fuhrmann M, Oertel W, Hegemann P. A synthetic gene coding for the green fluorescent protein (GFP) is a versatile reporter in Chlamydomonas reinhardtii. The Plant Journal : For Cell and Molecular Biology. 19: 353-61. PMID 10476082  1
1999 Ebnet E, Fischer M, Deininger W, Hegemann P. Volvoxrhodopsin, a light-regulated sensory photoreceptor of the spheroidal green alga Volvox carteri. The Plant Cell. 11: 1473-84. PMID 10449581 DOI: 10.1105/tpc.11.8.1473  1
1999 Braun FJ, Hegemann P. Direct measurement of cytosolic calcium and pH in living Chlamydomonas reinhardtii cells. European Journal of Cell Biology. 78: 199-208. PMID 10219570 DOI: 10.1016/S0171-9335(99)80099-5  1
1999 Braun FJ, Hegemann P. Two light-activated conductances in the eye of the green alga Volvox carteri. Biophysical Journal. 76: 1668-78. PMID 10049347 DOI: 10.1016/S0006-3495(99)77326-1  1
1997 Govorunova EG, Sineshchekov OA, Hegemann P. Desensitization and Dark Recovery of the Photoreceptor Current in Chlamydomonas reinhardtii. Plant Physiology. 115: 633-642. PMID 12223832  1
1997 Hegemann P. Vision in microalgae. Planta. 203: 265-74. PMID 9431675 DOI: 10.1007/s004250050191  1
1997 Holland EM, Harz H, Uhl R, Hegemann P. Control of phobic behavioral responses by rhodopsin-induced photocurrents in Chlamydomonas. Biophysical Journal. 73: 1395-401. PMID 9284306 DOI: 10.1016/S0006-3495(97)78171-2  1
1996 Nonnengässer C, Holland EM, Harz H, Hegemann P. The nature of rhodopsin-triggered photocurrents in Chlamydomonas. II. Influence of monovalent ions. Biophysical Journal. 70: 932-8. PMID 8789110 DOI: 10.1016/S0006-3495(96)79636-4  1
1996 Holland EM, Braun FJ, Nonnengässer C, Harz H, Hegemann P. The nature of rhodopsin-triggered photocurrents in Chlamydomonas. I. Kinetics and influence of divalent ions. Biophysical Journal. 70: 924-31. PMID 8789109 DOI: 10.1016/S0006-3495(96)79635-2  1
1995 Deininger W, Kröger P, Hegemann U, Lottspeich F, Hegemann P. Chlamyrhodopsin represents a new type of sensory photoreceptor. The Embo Journal. 14: 5849-58. PMID 8846778  1
1994 Kröger P, Hegemann P. Photophobic responses and phototaxis in Chlamydomonas are triggered by a single rhodopsin photoreceptor. Febs Letters. 341: 5-9. PMID 8137921 DOI: 10.1016/0014-5793(94)80229-7  1
1991 Beckmann M, Hegemann P. In vitro identification of rhodopsin in the green alga Chlamydomonas Biochemistry. 30: 3692-3697. PMID 2015225  1
1991 Hegemann P, Gartner W, Uhl R. All-trans retinal constitutes the functional chromophore in Chlamydomonas rhodopsin Biophysical Journal. 60: 1477-1489.  1
1991 Harz H, Hegemann P. Rhodopsin-regulated calcium currents in Chlamydomonas Nature. 351: 489-491.  1
1990 Hegemann P, Neumeier K, Hegemann U, Kuehnle E. The role of calcium in Chlamydomonas photomovement responses as analysed by calcium channel inhibitors Photochemistry and Photobiology. 52: 575-583. PMID 2284349  1
1990 Uhl R, Hegemann P. Adaptation of chlamydomonas phototaxis: I. A light-scattering apparatus for measuring the phototactic rate of microorganisms with high time resolution Cell Motility and the Cytoskeleton. 15: 230-244. DOI: 10.1002/cm.970150406  1
1990 Uhl R, Hegemann P. Probing visual transduction in a plant cell. Optical recording of rhodopsin-induced structural changes from Chlamydomonas reinhardtii Biophysical Journal. 58: 1295-1302.  1
1989 Hegemann P, Bruck B. Light-induced stop response in chlamydomonas reinhartii: Occurrence and adaptation phenomena Cell Motility and the Cytoskeleton. 14: 501-515.  1
1988 Hegemann P, Hegemann U, Foster KW. Reversible bleaching of Chlamydomonas reinhardtii rhodopsin in vivo. Photochemistry and Photobiology. 48: 123-8. PMID 3217436  1
1988 Marwan W, Hegemann P, Oesterhelt D. Single photon detection by an archaebacterium. Journal of Molecular Biology. 199: 663-4. PMID 3127593 DOI: 10.1016/0022-2836(88)90309-9  1
1987 Hegemann P, Blanck A, Vogelsang-Wenke H, Lottspeich F, Oesterhelt D. The halo-opsin gene. I. Identification and isolation. The Embo Journal. 6: 259-64. PMID 15981335  1
1986 Oesterhelt D, Hegemann P, Tavan P, Schulten K. Trans-cis isomerization of retinal and a mechanism for ion translocation in halorhodopsin European Biophysics Journal. 14: 123-129. DOI: 10.1007/BF00263069  1
1985 Oesterhelt D, Hegemann P, Tittor J. The photocycle of the chloride pump halorhodopsin. II: Quantum yields and a kinetic model. The Embo Journal. 4: 2351-6. PMID 15938054  1
1985 Hegemann P, Oesterbelt D, Steiner M. The photocycle of the chloride pump halorhodopsin. I: Azide-catalyzed deprotonation of the chromophore is a side reaction of photocycle intermediates inactivating the pump The Embo Journal. 4: 2347-2350. PMID 15938053  1
1985 Polland HJ, Franz MA, Zinth W, Kaiser W, Hegemann P, Oesterhelt D. Picosecond events in the photochemical cycle of the light-driven chloride-pump halorhodopsin. Biophysical Journal. 47: 55-9. PMID 3978190 DOI: 10.1016/S0006-3495(85)83876-5  1
1985 Alshuth T, Stockburger M, Hegemann P, Oesterhelt D. Structure of the retinal chromophore in halorhodopsin. A resonance Raman study Febs Letters. 179: 55-59. DOI: 10.1016/0014-5793(85)80190-3  1
1985 Hegemann P, Oesterhelt D, Bamberg E. The transport activity of the light-driven chloride pump halorhodopsin is regulated by green and blue light Bba - Biomembranes. 819: 195-205. DOI: 10.1016/0005-2736(85)90174-9  1
1984 Barnberg E, Hegemann P, Oesterhelt D. The chromoprotein of halorhodopsin is the light-driven electrogenic chloride pump in halobacterium halobiumt. Biochemistry. 23: 6216-21. PMID 24409552  1
1984 Bamberg E, Hegemann P, Oesterhelt D. Reconstitution of halorhodopsin in black lipid membranes. Progress in Clinical and Biological Research. 164: 73-9. PMID 6522408  1
1984 Bamberg E, Hegemann P, Oesterhelt D. Reconstitution of the light-driven electrogenic ion pump halorhodopsin in black lipid membranes Bba - Biomembranes. 773: 53-60. DOI: 10.1016/0005-2736(84)90549-2  1
1984 Polland HJ, Franz MA, Zinth W, Kaiser W, Hegemann P, Oesterhelt D. PICOSECOND MEASUREMENTS ON HALORHODOPSIN OF HALOBACTERIUM HALOBIUM . 15.  1
1982 Hegemann P, Steiner M, Oesterhelt D. Isolation and characterization of the retinal-binding component of halorhodopsin. The Embo Journal. 1: 1177-83. PMID 16453434  1
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