| Year |
Citation |
Score |
| 2023 |
Bardwell L, Thorner J. Mitogen-activated protein kinase (MAPK) cascades-A yeast perspective. The Enzymes. 54: 137-170. PMID 37945169 DOI: 10.1016/bs.enz.2023.07.001 |
0.424 |
|
| 2023 |
Emmerstorfer-Augustin A, Thorner J. Regulation of TORC2 Function and Localization in Yeast. Annual Review of Cell and Developmental Biology. PMID 37339679 DOI: 10.1146/annurev-cellbio-011723-030346 |
0.342 |
|
| 2022 |
Thorner J. TOR complex 2 is a master regulator of plasma membrane homeostasis. The Biochemical Journal. 479: 1917-1940. PMID 36149412 DOI: 10.1042/BCJ20220388 |
0.351 |
|
| 2021 |
Patterson JC, Goupil LS, Thorner J. Cdc42-Specific GTPase-Activating Protein Rga1 Squelches Crosstalk between the High-Osmolarity Glycerol (HOG) and Mating Pheromone Response MAPK Pathways. Biomolecules. 11. PMID 34680163 DOI: 10.3390/biom11101530 |
0.665 |
|
| 2021 |
Galez HA, Roelants FM, Palm SM, Reynaud KK, Ingolia NT, Thorner J. Phosphorylation of mRNA-Binding Proteins Puf1 and Puf2 by TORC2-Activated Protein Kinase Ypk1 Alleviates Their Repressive Effects. Membranes. 11. PMID 34209236 DOI: 10.3390/membranes11070500 |
0.374 |
|
| 2021 |
Takagi J, Cho C, Duvalyan A, Yan Y, Halloran M, Hanson-Smith V, Thorner J, Finnigan GC. Reconstructed evolutionary history of the yeast septins Cdc11 and Shs1. G3 (Bethesda, Md.). 11. PMID 33561226 DOI: 10.1093/g3journal/jkaa006 |
0.321 |
|
| 2019 |
McMurray MA, Thorner J. Turning it inside out: The organization of human septin heterooligomers. Cytoskeleton (Hoboken, N.J.). PMID 31614074 DOI: 10.1002/cm.21571 |
0.69 |
|
| 2019 |
Locke MN, Thorner J. Regulation of TORC2 function and localization by Rab5 GTPases in Saccharomyces cerevisiae. Cell Cycle (Georgetown, Tex.). 1-11. PMID 31068077 DOI: 10.1080/15384101.2019.1616999 |
0.508 |
|
| 2019 |
Marshall MNM, Emmerstorfer-Augustin A, Leskoske KL, Zhang LH, Li B, Thorner J. Analysis of the roles of phosphatidylinositol-4,5- bisphosphate and individual subunits in assembly, localization and function of Saccharomyces cerevisiae Target of Rapamycin Complex 2. Molecular Biology of the Cell. mbcE18100682. PMID 30969890 DOI: 10.1091/mbc.E18-10-0682 |
0.43 |
|
| 2018 |
Locke MN, Thorner J. Rab5 GTPases are required for optimal TORC2 function. The Journal of Cell Biology. PMID 30578283 DOI: 10.1083/jcb.201807154 |
0.511 |
|
| 2018 |
Leskoske KL, Roelants FM, Emmerstorfer-Augustin A, Augustin CM, Si EP, Hill JM, Thorner J. Phosphorylation by the stress-activated MAPK Slt2 down-regulates the yeast TOR complex 2. Genes & Development. PMID 30478248 DOI: 10.1101/gad.318709.118 |
0.521 |
|
| 2018 |
Perez AM, Thorner J. Septin-associated proteins Aim44 and Nis1 traffic between the bud neck and the nucleus in the yeast Saccharomyces cerevisiae. Cytoskeleton (Hoboken, N.J.). PMID 30341817 DOI: 10.1002/cm.21500 |
0.416 |
|
| 2018 |
Emmerstorfer-Augustin A, Augustin CM, Shams S, Thorner J. Tracking yeast pheromone receptor Ste2 endocytosis using fluorogen-activating protein (FAP) tagging. Molecular Biology of the Cell. mbcE18070424. PMID 30207829 DOI: 10.1091/mbc.E18-07-0424 |
0.41 |
|
| 2018 |
Roelants FM, Chauhan N, Muir A, Davis JC, Menon AK, Levine TP, Thorner J. TOR Complex 2-regulated protein kinase Ypk1 controls sterol distribution by inhibiting StARkin domain-containing proteins located at plasma membrane-endoplasmic reticulum contact sites. Molecular Biology of the Cell. mbcE18040229. PMID 29927351 DOI: 10.1091/Mbc.E18-04-0229 |
0.441 |
|
| 2017 |
Roelants FM, Leskoske KL, Martinez Marshall MN, Locke MN, Thorner J. The TORC2-Dependent Signaling Network in the Yeast Saccharomyces cerevisiae. Biomolecules. 7. PMID 28872598 DOI: 10.3390/biom7030066 |
0.415 |
|
| 2017 |
Leskoske KL, Roelants FM, Martinez Marshall MN, Hill JM, Thorner J. The Stress-Sensing TORC2 Complex Activates Yeast AGC-Family Protein Kinase Ypk1 at Multiple Novel Sites. Genetics. PMID 28739659 DOI: 10.1534/genetics.117.1124 |
0.516 |
|
| 2017 |
Roelants FM, Leskoske KL, Pedersen RT, Muir A, Liu JM, Finnigan GC, Thorner J. TOR Complex 2-regulated protein kinase Fpk1 stimulates endocytosis via inhibition of Ark1/Prk1-related protein kinase Akl1 in Saccharomyces cerevisiae. Molecular and Cellular Biology. PMID 28069741 DOI: 10.1128/Mcb.00627-16 |
0.505 |
|
| 2016 |
Perez AM, Finnigan GC, Roelants FM, Thorner J. Septin-Associated Protein Kinases in the Yeast Saccharomyces cerevisiae. Frontiers in Cell and Developmental Biology. 4: 119. PMID 27847804 DOI: 10.3389/Fcell.2016.00119 |
0.516 |
|
| 2016 |
Booth EA, Sterling SM, Dovala D, Nogales E, Thorner J. Effects of Bni5 Binding on Septin Filament Organization. Journal of Molecular Biology. PMID 27806918 DOI: 10.1016/J.Jmb.2016.10.024 |
0.419 |
|
| 2016 |
Sen A, Acosta-Sampson L, Alvaro CG, Ahn JS, Cate JH, Thorner J. Internalization of heterologous sugar transporters by endogenous alpha-arrestins in the yeast Saccharomyces cerevisiae. Applied and Environmental Microbiology. PMID 27694235 DOI: 10.1128/Aem.02148-16 |
0.366 |
|
| 2016 |
Guerreiro JF, Muir A, Ramachandran S, Thorner J, Sá-Correia I. Sphingolipid biosynthesis upregulation by TOR Complex 2-Ypk1 signaling during yeast adaptive response to acetic acid stress. The Biochemical Journal. PMID 27671892 DOI: 10.1042/Bcj20160565 |
0.36 |
|
| 2016 |
Booth EA, Thorner J. A FRET-based method for monitoring septin polymerization and binding of septin-associated proteins. Methods in Cell Biology. 136: 35-56. PMID 27473902 DOI: 10.1016/bs.mcb.2016.03.024 |
0.407 |
|
| 2016 |
Finnigan GC, Duvalyan A, Liao EN, Sargsyan A, Thorner J. Detection of protein-protein interactions at the septin collar in Saccharomyces cerevisiae using a tripartite split-GFP system. Molecular Biology of the Cell. PMID 27385335 DOI: 10.1091/Mbc.E16-05-0337 |
0.409 |
|
| 2016 |
Finnigan GC, Sterling SM, Duvalyan A, Liao EN, Sargsyan A, Garcia G, Nogales E, Thorner J. Coordinate action of distinct sequence elements localizes checkpoint kinase Hsl1 to the septin collar at the bud neck in Saccharomyces cerevisiae. Molecular Biology of the Cell. PMID 27193302 DOI: 10.1091/Mbc.E16-03-0177 |
0.468 |
|
| 2016 |
Garcia G, Finnigan GC, Heasley LR, Sterling SM, Aggarwal A, Pearson CG, Nogales E, McMurray MA, Thorner J. Assembly, molecular organization, and membrane-binding properties of development-specific septins. The Journal of Cell Biology. 212: 515-29. PMID 26929450 DOI: 10.1083/Jcb.201511029 |
0.806 |
|
| 2016 |
Alvaro CG, Aindow A, Thorner J. Differential Phosphorylation Provides a Switch to Control How α-Arrestin Rod1 Down-Regulates Mating Pheromone Response in Saccharomyces cerevisiae. Genetics. PMID 26920760 DOI: 10.1534/genetics.115.186122 |
0.482 |
|
| 2016 |
Alvaro CG, Thorner J. Heterotrimeric-G-protein-coupled Receptor Signaling in Yeast Mating Pheromone Response. The Journal of Biological Chemistry. PMID 26907689 DOI: 10.1074/jbc.R116.714980 |
0.343 |
|
| 2016 |
Klionsky DJ, Abdelmohsen K, Abe A, Abedin J, Abeliovich H, Arozena AA, Adachi H, Adams CM, Adams PD, Adeli K, Adhihetty PJ, Adler SG, Agam G, Agarwal R, Aghi MK, ... ... Thorner J, et al. Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356 Autophagy. 12: 443-443. PMID 26902590 DOI: 10.1080/15548627.2016.1147886 |
0.447 |
|
| 2016 |
Klionsky DJ, Abdelmohsen K, Abe A, Abedin MJ, Abeliovich H, Acevedo Arozena A, Adachi H, Adams CM, Adams PD, Adeli K, Adhihetty PJ, Adler SG, Agam G, Agarwal R, Aghi MK, ... ... Thorner J, et al. Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy. 12: 1-222. PMID 26799652 DOI: 10.1080/15548627.2015.1100356 |
0.594 |
|
| 2015 |
Prosser DC, Pannunzio AE, Brodsky JL, Thorner J, Wendland B, O'Donnell AF. Alpha-arrestins participate in cargo selection for both clathrin-independent and clathrin-mediated endocytosis. Journal of Cell Science. PMID 26459639 DOI: 10.1242/Jcs.175372 |
0.411 |
|
| 2015 |
Booth EA, Vane EW, Dovala D, Thorner J. A Foerster Resonance Energy Transfer (FRET)-based System Provides Insight into the Ordered Assembly of Yeast Septin Hetero-octamers. The Journal of Biological Chemistry. PMID 26416886 DOI: 10.1074/jbc.M115.683128 |
0.458 |
|
| 2015 |
Muir A, Roelants FM, Timmons G, Leskoske KL, Thorner J. Down-regulation of TORC2-Ypk1 signaling promotes MAPK-independent survival under hyperosmotic stress. Elife. 4. PMID 26274562 DOI: 10.7554/eLife.09336 |
0.418 |
|
| 2015 |
Finnigan GC, Booth EA, Duvalyan A, Liao EN, Thorner J. The Carboxy-Terminal Tails of Septins Cdc11 and Shs1 Recruit Myosin-II Binding Factor Bni5 to the Bud Neck in Saccharomyces cerevisiae. Genetics. 200: 821-40. PMID 25971666 DOI: 10.1534/Genetics.115.176503 |
0.441 |
|
| 2015 |
Finnigan GC, Takagi J, Cho C, Thorner J. Comprehensive Genetic Analysis of Paralogous Terminal Septin Subunits Shs1 and Cdc11 in Saccharomyces cerevisiae. Genetics. 200: 841-61. PMID 25971665 DOI: 10.1534/Genetics.115.176495 |
0.473 |
|
| 2015 |
Johnson CR, Weems AD, Brewer JM, Thorner J, McMurray MA. Cytosolic chaperones mediate quality control of higher-order septin assembly in budding yeast. Molecular Biology of the Cell. 26: 1323-44. PMID 25673805 DOI: 10.1091/mbc.E14-11-1531 |
0.72 |
|
| 2015 |
Roelants FM, Su BM, von Wulffen J, Ramachandran S, Sartorel E, Trott AE, Thorner J. Protein kinase Gin4 negatively regulates flippase function and controls plasma membrane asymmetry. The Journal of Cell Biology. 208: 299-311. PMID 25646086 DOI: 10.1085/Jgp.1453Oia6 |
0.463 |
|
| 2015 |
O'Donnell AF, McCartney RR, Chandrashekarappa DG, Zhang BB, Thorner J, Schmidt MC. 2-Deoxyglucose impairs Saccharomyces cerevisiae growth by stimulating Snf1-regulated and α-arrestin-mediated trafficking of hexose transporters 1 and 3. Molecular and Cellular Biology. 35: 939-55. PMID 25547292 DOI: 10.1128/Mcb.01183-14 |
0.379 |
|
| 2015 |
Sartorel E, Barrey E, Lau RK, Thorner J. Plasma membrane aminoglycerolipid flippase function is required for signaling competence in the yeast mating pheromone response pathway. Molecular Biology of the Cell. 26: 134-50. PMID 25378585 DOI: 10.1091/mbc.E14-07-1193 |
0.396 |
|
| 2015 |
Muir A, Roelants FM, Timmons G, Leskoske KL, Thorner J. Author response: Down-regulation of TORC2-Ypk1 signaling promotes MAPK-independent survival under hyperosmotic stress Elife. DOI: 10.7554/Elife.09336.014 |
0.306 |
|
| 2014 |
Thorner J, Hunter T, Cantley LC, Sever R. Signal transduction: From the atomic age to the post-genomic era. Cold Spring Harbor Perspectives in Biology. 6: a022913. PMID 25359498 DOI: 10.1101/Cshperspect.A022913 |
0.331 |
|
| 2014 |
Muir A, Ramachandran S, Roelants FM, Timmons G, Thorner J. TORC2-dependent protein kinase Ypk1 phosphorylates ceramide synthase to stimulate synthesis of complex sphingolipids. Elife. 3. PMID 25279700 DOI: 10.7554/Elife.03779 |
0.472 |
|
| 2014 |
Alvaro CG, O'Donnell AF, Prosser DC, Augustine AA, Goldman A, Brodsky JL, Cyert MS, Wendland B, Thorner J. Specific α-arrestins negatively regulate Saccharomyces cerevisiae pheromone response by down-modulating the G-protein-coupled receptor Ste2. Molecular and Cellular Biology. 34: 2660-81. PMID 24820415 DOI: 10.1128/Mcb.00230-14 |
0.727 |
|
| 2014 |
Muir A, Ramachandran S, Roelants FM, Timmons G, Thorner J. Author response: TORC2-dependent protein kinase Ypk1 phosphorylates ceramide synthase to stimulate synthesis of complex sphingolipids Elife. DOI: 10.7554/Elife.03779.015 |
0.427 |
|
| 2014 |
Booth E, Vane E, Thorner J. A FRET-Based Method for Measurement of Yeast Septin Filament Formation In Vitro Biophysical Journal. 106: 55a. DOI: 10.1016/j.bpj.2013.11.385 |
0.405 |
|
| 2013 |
O'Donnell AF, Huang L, Thorner J, Cyert MS. A calcineurin-dependent switch controls the trafficking function of α-arrestin Aly1/Art6. The Journal of Biological Chemistry. 288: 24063-80. PMID 23824189 DOI: 10.1074/Jbc.M113.478511 |
0.712 |
|
| 2013 |
de Val N, McMurray MA, Lam LH, Hsiung CC, Bertin A, Nogales E, Thorner J. Native cysteine residues are dispensable for the structure and function of all five yeast mitotic septins. Proteins. 81: 1964-79. PMID 23775754 DOI: 10.1002/Prot.24345 |
0.787 |
|
| 2012 |
Wu HJ, Henzie J, Lin WC, Rhodes C, Li Z, Sartorel E, Thorner J, Yang P, Groves JT. Membrane-protein binding measured with solution-phase plasmonic nanocube sensors. Nature Methods. 9: 1189-91. PMID 23085614 DOI: 10.1038/Nmeth.2211 |
0.308 |
|
| 2012 |
Lee YJ, Jeschke GR, Roelants FM, Thorner J, Turk BE. Reciprocal phosphorylation of yeast glycerol-3-phosphate dehydrogenases in adaptation to distinct types of stress. Molecular and Cellular Biology. 32: 4705-17. PMID 22988299 DOI: 10.1128/MCB.00897-12 |
0.464 |
|
| 2012 |
Bertin A, McMurray MA, Pierson J, Thai L, McDonald KL, Zehr EA, García G, Peters P, Thorner J, Nogales E. Three-dimensional ultrastructure of the septin filament network in Saccharomyces cerevisiae. Molecular Biology of the Cell. 23: 423-32. PMID 22160597 DOI: 10.1091/Mbc.E11-10-0850 |
0.713 |
|
| 2011 |
Garcia G, Bertin A, Li Z, Song Y, McMurray MA, Thorner J, Nogales E. Subunit-dependent modulation of septin assembly: budding yeast septin Shs1 promotes ring and gauze formation. The Journal of Cell Biology. 195: 993-1004. PMID 22144691 DOI: 10.1083/Jcb.201107123 |
0.741 |
|
| 2011 |
Roelants FM, Breslow DK, Muir A, Weissman JS, Thorner J. Protein kinase Ypk1 phosphorylates regulatory proteins Orm1 and Orm2 to control sphingolipid homeostasis in Saccharomyces cerevisiae. Proceedings of the National Academy of Sciences of the United States of America. 108: 19222-7. PMID 22080611 DOI: 10.1073/Pnas.1116948108 |
0.537 |
|
| 2011 |
McMurray MA, Stefan CJ, Wemmer M, Odorizzi G, Emr SD, Thorner J. Genetic interactions with mutations affecting septin assembly reveal ESCRT functions in budding yeast cytokinesis. Biological Chemistry. 392: 699-712. PMID 21824003 DOI: 10.1515/Bc.2011.091 |
0.727 |
|
| 2011 |
McMurray MA, Bertin A, Garcia G, Lam L, Nogales E, Thorner J. Septin filament formation is essential in budding yeast. Developmental Cell. 20: 540-9. PMID 21497764 DOI: 10.1016/J.Devcel.2011.02.004 |
0.737 |
|
| 2011 |
Lim S, Strahl T, Thorner J, Ames JB. Structure of a Ca2+-myristoyl switch protein that controls activation of a phosphatidylinositol 4-kinase in fission yeast. The Journal of Biological Chemistry. 286: 12565-77. PMID 21288895 DOI: 10.1074/Jbc.M110.208868 |
0.369 |
|
| 2010 |
Patterson JC, Klimenko ES, Thorner J. Single-cell analysis reveals that insulation maintains signaling specificity between two yeast MAPK pathways with common components. Science Signaling. 3: ra75. PMID 20959523 DOI: 10.1126/Scisignal.2001275 |
0.822 |
|
| 2010 |
Bertin A, McMurray MA, Thai L, Garcia G, Votin V, Grob P, Allyn T, Thorner J, Nogales E. Phosphatidylinositol-4,5-bisphosphate promotes budding yeast septin filament assembly and organization. Journal of Molecular Biology. 404: 711-31. PMID 20951708 DOI: 10.1016/J.Jmb.2010.10.002 |
0.727 |
|
| 2010 |
Chen RE, Patterson JC, Goupil LS, Thorner J. Dynamic localization of Fus3 mitogen-activated protein kinase is necessary to evoke appropriate responses and avoid cytotoxic effects. Molecular and Cellular Biology. 30: 4293-307. PMID 20584989 DOI: 10.1128/Mcb.00361-10 |
0.778 |
|
| 2010 |
Garrenton LS, Stefan CJ, McMurray MA, Emr SD, Thorner J. Pheromone-induced anisotropy in yeast plasma membrane phosphatidylinositol-4,5-bisphosphate distribution is required for MAPK signaling. Proceedings of the National Academy of Sciences of the United States of America. 107: 11805-10. PMID 20547860 DOI: 10.1073/Pnas.1005817107 |
0.718 |
|
| 2010 |
Chen RE, Thorner J. Systematic epistasis analysis of the contributions of protein kinase A- and mitogen-activated protein kinase-dependent signaling to nutrient limitation-evoked responses in the yeast Saccharomyces cerevisiae. Genetics. 185: 855-70. PMID 20421603 DOI: 10.1534/Genetics.110.115808 |
0.722 |
|
| 2010 |
Roelants FM, Baltz AG, Trott AE, Fereres S, Thorner J. A protein kinase network regulates the function of aminophospholipid flippases. Proceedings of the National Academy of Sciences of the United States of America. 107: 34-9. PMID 19966303 DOI: 10.1073/pnas.0912497106 |
0.502 |
|
| 2010 |
Bertin A, McMurray M, Thai L, Garcia G, Thorner J, Nogales E. Ultrastructural Organization of Budding Yeast Septin Filaments Both in vitro and in situ, Analyzed by Electron Microscopy Biophysical Journal. 98: 384a. DOI: 10.1016/J.Bpj.2009.12.2069 |
0.728 |
|
| 2009 |
McMurray MA, Thorner J. Septins: molecular partitioning and the generation of cellular asymmetry. Cell Division. 4: 18. PMID 19709431 DOI: 10.1186/1747-1028-4-18 |
0.709 |
|
| 2009 |
Rockwell NC, Wolfger H, Kuchler K, Thorner J. ABC transporter Pdr10 regulates the membrane microenvironment of Pdr12 in Saccharomyces cerevisiae. The Journal of Membrane Biology. 229: 27-52. PMID 19452121 DOI: 10.1007/s00232-009-9173-5 |
0.327 |
|
| 2009 |
McMurray MA, Thorner J. Reuse, replace, recycle. Specificity in subunit inheritance and assembly of higher-order septin structures during mitotic and meiotic division in budding yeast. Cell Cycle (Georgetown, Tex.). 8: 195-203. PMID 19164941 |
0.703 |
|
| 2009 |
Garrenton LS, Braunwarth A, Irniger S, Hurt E, Künzler M, Thorner J. Nucleus-specific and cell cycle-regulated degradation of mitogen-activated protein kinase scaffold protein Ste5 contributes to the control of signaling competence. Molecular and Cellular Biology. 29: 582-601. PMID 19001089 DOI: 10.1128/Mcb.01019-08 |
0.52 |
|
| 2008 |
Westfall PJ, Patterson JC, Chen RE, Thorner J. Stress resistance and signal fidelity independent of nuclear MAPK function. Proceedings of the National Academy of Sciences of the United States of America. 105: 12212-7. PMID 18719124 DOI: 10.1073/Pnas.0805797105 |
0.762 |
|
| 2008 |
McMurray MA, Thorner J. Septin stability and recycling during dynamic structural transitions in cell division and development. Current Biology : Cb. 18: 1203-8. PMID 18701287 DOI: 10.1016/j.cub.2008.07.020 |
0.735 |
|
| 2008 |
Bertin A, McMurray MA, Grob P, Park SS, Garcia G, Patanwala I, Ng HL, Alber T, Thorner J, Nogales E. Saccharomyces cerevisiae septins: supramolecular organization of heterooligomers and the mechanism of filament assembly. Proceedings of the National Academy of Sciences of the United States of America. 105: 8274-9. PMID 18550837 DOI: 10.1073/Pnas.0803330105 |
0.743 |
|
| 2008 |
McMurray MA, Thorner J. Biochemical Properties and Supramolecular Architecture of Septin Hetero-Oligomers and Septin Filaments The Septins. 47-100. DOI: 10.1002/9780470779705.ch3 |
0.632 |
|
| 2007 |
Schüller C, Mamnun YM, Wolfger H, Rockwell N, Thorner J, Kuchler K. Membrane-active compounds activate the transcription factors Pdr1 and Pdr3 connecting pleiotropic drug resistance and membrane lipid homeostasis in saccharomyces cerevisiae. Molecular Biology of the Cell. 18: 4932-44. PMID 17881724 DOI: 10.1091/mbc.E07-06-0610 |
0.362 |
|
| 2007 |
Strahl T, Huttner IG, Lusin JD, Osawa M, King D, Thorner J, Ames JB. Structural insights into activation of phosphatidylinositol 4-kinase (Pik1) by yeast frequenin (Frq1). The Journal of Biological Chemistry. 282: 30949-59. PMID 17720810 DOI: 10.1074/Jbc.M705499200 |
0.408 |
|
| 2007 |
Chen RE, Thorner J. Function and regulation in MAPK signaling pathways: lessons learned from the yeast Saccharomyces cerevisiae. Biochimica Et Biophysica Acta. 1773: 1311-40. PMID 17604854 DOI: 10.1016/J.Bbamcr.2007.05.003 |
0.692 |
|
| 2007 |
Strahl T, Thorner J. Synthesis and function of membrane phosphoinositides in budding yeast, Saccharomyces cerevisiae. Biochimica Et Biophysica Acta. 1771: 353-404. PMID 17382260 DOI: 10.1016/j.bbalip.2007.01.015 |
0.451 |
|
| 2006 |
Ballon DR, Flanary PL, Gladue DP, Konopka JB, Dohlman HG, Thorner J. DEP-domain-mediated regulation of GPCR signaling responses. Cell. 126: 1079-93. PMID 16990133 DOI: 10.1016/J.Cell.2006.07.030 |
0.778 |
|
| 2006 |
Westfall PJ, Thorner J. Analysis of mitogen-activated protein kinase signaling specificity in response to hyperosmotic stress: use of an analog-sensitive HOG1 allele. Eukaryotic Cell. 5: 1215-28. PMID 16896207 DOI: 10.1128/EC.00037-06 |
0.494 |
|
| 2006 |
Asano S, Park JE, Yu LR, Zhou M, Sakchaisri K, Park CJ, Kang YH, Thorner J, Veenstra TD, Lee KS. Direct phosphorylation and activation of a Nim1-related kinase Gin4 by Elm1 in budding yeast. The Journal of Biological Chemistry. 281: 27090-8. PMID 16861226 DOI: 10.1074/jbc.M601483200 |
0.498 |
|
| 2006 |
Garrenton LS, Young SL, Thorner J. Function of the MAPK scaffold protein, Ste5, requires a cryptic PH domain. Genes & Development. 20: 1946-58. PMID 16847350 DOI: 10.1101/gad.1413706 |
0.364 |
|
| 2006 |
Weirich CS, Erzberger JP, Flick JS, Berger JM, Thorner J, Weis K. Activation of the DExD/H-box protein Dbp5 by the nuclear-pore protein Gle1 and its coactivator InsP6 is required for mRNA export. Nature Cell Biology. 8: 668-76. PMID 16783364 DOI: 10.1038/Ncb1424 |
0.364 |
|
| 2006 |
Truckses DM, Bloomekatz JE, Thorner J. The RA domain of Ste50 adaptor protein is required for delivery of Ste11 to the plasma membrane in the filamentous growth signaling pathway of the yeast Saccharomyces cerevisiae. Molecular and Cellular Biology. 26: 912-28. PMID 16428446 DOI: 10.1128/MCB.26.3.912-928.2006 |
0.468 |
|
| 2005 |
Strahl T, Hama H, DeWald DB, Thorner J. Yeast phosphatidylinositol 4-kinase, Pik1, has essential roles at the Golgi and in the nucleus. The Journal of Cell Biology. 171: 967-79. PMID 16365163 DOI: 10.1083/Jcb.200504104 |
0.436 |
|
| 2005 |
Chen RE, Thorner J. Systems biology approaches in cell signaling research. Genome Biology. 6: 235. PMID 16207364 DOI: 10.1186/Gb-2005-6-10-235 |
0.632 |
|
| 2005 |
Versele M, Thorner J. Some assembly required: yeast septins provide the instruction manual. Trends in Cell Biology. 15: 414-24. PMID 16009555 DOI: 10.1016/j.tcb.2005.06.007 |
0.453 |
|
| 2005 |
Rodríguez-Escudero I, Roelants FM, Thorner J, Nombela C, Molina M, Cid VJ. Reconstitution of the mammalian PI3K/PTEN/Akt pathway in yeast. The Biochemical Journal. 390: 613-23. PMID 15913452 DOI: 10.1042/BJ20050574 |
0.512 |
|
| 2004 |
Westfall PJ, Ballon DR, Thorner J. When the stress of your environment makes you go HOG wild. Science (New York, N.Y.). 306: 1511-2. PMID 15567851 DOI: 10.1126/Science.1104879 |
0.782 |
|
| 2004 |
Truckses DM, Garrenton LS, Thorner J. Jekyll and Hyde in the microbial world. Science (New York, N.Y.). 306: 1509-11. PMID 15567850 DOI: 10.1126/science.1104677 |
0.506 |
|
| 2004 |
Roelants FM, Torrance PD, Thorner J. Differential roles of PDK1- and PDK2-phosphorylation sites in the yeast AGC kinases Ypk1, Pkc1 and Sch9. Microbiology (Reading, England). 150: 3289-304. PMID 15470109 DOI: 10.1099/Mic.0.27286-0 |
0.813 |
|
| 2004 |
Versele M, Gullbrand B, Shulewitz MJ, Cid VJ, Bahmanyar S, Chen RE, Barth P, Alber T, Thorner J. Protein-protein interactions governing septin heteropentamer assembly and septin filament organization in Saccharomyces cerevisiae. Molecular Biology of the Cell. 15: 4568-83. PMID 15282341 DOI: 10.1091/Mbc.E04-04-0330 |
0.807 |
|
| 2004 |
Sakchaisri K, Asano S, Yu LR, Shulewitz MJ, Park CJ, Park JE, Cho YW, Veenstra TD, Thorner J, Lee KS. Coupling morphogenesis to mitotic entry. Proceedings of the National Academy of Sciences of the United States of America. 101: 4124-9. PMID 15037762 DOI: 10.1073/Pnas.0400641101 |
0.819 |
|
| 2004 |
Versele M, Thorner J. Septin collar formation in budding yeast requires GTP binding and direct phosphorylation by the PAK, Cla4. The Journal of Cell Biology. 164: 701-15. PMID 14993234 DOI: 10.1083/jcb.200312070 |
0.336 |
|
| 2004 |
Rudge SA, Sciorra VA, Iwamoto M, Zhou C, Strahl T, Morris AJ, Thorner J, Engebrecht J. Roles of phosphoinositides and of Spo14p (phospholipase D)-generated phosphatidic acid during yeast sporulation. Molecular Biology of the Cell. 15: 207-18. PMID 14528019 DOI: 10.1091/Mbc.E03-04-0245 |
0.409 |
|
| 2004 |
Sakchaisri K, Asano S, Yu LR, Shulewitz J, Park CJ, Park JE, Cho YW, Veenstra TD, Thorner J, Lee KS. Integration of Cell Cycle Signals by Swe1 Protein Kinase Science Signaling. 111. DOI: 10.1126/Stke.2262004Tw111 |
0.456 |
|
| 2003 |
Strahl T, Grafelmann B, Dannenberg J, Thorner J, Pongs O. Conservation of regulatory function in calcium-binding proteins: human frequenin (neuronal calcium sensor-1) associates productively with yeast phosphatidylinositol 4-kinase isoform, Pik1. The Journal of Biological Chemistry. 278: 49589-99. PMID 14512421 DOI: 10.1074/Jbc.M309017200 |
0.406 |
|
| 2003 |
Wang Y, Ge Q, Houston D, Thorner J, Errede B, Dohlman HG. Regulation of Ste7 ubiquitination by Ste11 phosphorylation and the Skp1-Cullin-F-box complex. The Journal of Biological Chemistry. 278: 22284-9. PMID 12668671 DOI: 10.1074/Jbc.M301272200 |
0.747 |
|
| 2003 |
Huttner IG, Strahl T, Osawa M, King DS, Ames JB, Thorner J. Molecular interactions of yeast frequenin (Frq1) with the phosphatidylinositol 4-kinase isoform, Pik1. The Journal of Biological Chemistry. 278: 4862-74. PMID 12477731 DOI: 10.1074/Jbc.M207920200 |
0.38 |
|
| 2002 |
Roelants FM, Torrance PD, Bezman N, Thorner J. Pkh1 and Pkh2 differentially phosphorylate and activate Ypk1 and Ykr2 and define protein kinase modules required for maintenance of cell wall integrity. Molecular Biology of the Cell. 13: 3005-28. PMID 12221112 DOI: 10.1091/Mbc.E02-04-0201 |
0.821 |
|
| 2002 |
Rayner TF, Gray JV, Thorner JW. Direct and novel regulation of cAMP-dependent protein kinase by Mck1p, a yeast glycogen synthase kinase-3. The Journal of Biological Chemistry. 277: 16814-22. PMID 11877433 DOI: 10.1074/jbc.M112349200 |
0.376 |
|
| 2001 |
Cid VJ, Shulewitz MJ, McDonald KL, Thorner J. Dynamic localization of the Swe1 regulator Hsl7 during the Saccharomyces cerevisiae cell cycle. Molecular Biology of the Cell. 12: 1645-69. PMID 11408575 DOI: 10.1091/Mbc.12.6.1645 |
0.832 |
|
| 2001 |
Dohlman HG, Thorner JW. Regulation of G protein-initiated signal transduction in yeast: paradigms and principles. Annual Review of Biochemistry. 70: 703-54. PMID 11395421 DOI: 10.1146/Annurev.Biochem.70.1.703 |
0.623 |
|
| 2001 |
Adamkewicz JI, Hansen KE, Prud'homme WA, Davis JL, Thorner J. High affinity interaction of yeast transcriptional regulator, Mot1, with TATA box-binding protein (TBP). The Journal of Biological Chemistry. 276: 11883-94. PMID 11278722 DOI: 10.1074/jbc.M010665200 |
0.377 |
|
| 2001 |
Bardwell AJ, Flatauer LJ, Matsukuma K, Thorner J, Bardwell L. A conserved docking site in MEKs mediates high-affinity binding to MAP kinases and cooperates with a scaffold protein to enhance signal transmission. The Journal of Biological Chemistry. 276: 10374-86. PMID 11134045 DOI: 10.1074/Jbc.M010271200 |
0.448 |
|
| 2000 |
Sette C, Inouye CJ, Stroschein SL, Iaquinta PJ, Thorner J. Mutational analysis suggests that activation of the yeast pheromone response mitogen-activated protein kinase pathway involves conformational changes in the Ste5 scaffold protein. Molecular Biology of the Cell. 11: 4033-49. PMID 11071925 DOI: 10.1091/Mbc.11.11.4033 |
0.466 |
|
| 2000 |
Adamkewicz JI, Mueller CG, Hansen KE, Prud'homme WA, Thorner J. Purification and enzymic properties of Mot1 ATPase, a regulator of basal transcription in the yeast Saccharomyces cerevisiae. The Journal of Biological Chemistry. 275: 21158-68. PMID 10887203 DOI: 10.1074/jbc.M002639200 |
0.416 |
|
| 2000 |
Petersen C, Orem N, Trueheart J, Thorner JW, Macara IG. Random mutagenesis and functional analysis of the Ran-binding protein, RanBP1. The Journal of Biological Chemistry. 275: 4081-91. PMID 10660567 DOI: 10.1074/Jbc.275.6.4081 |
0.316 |
|
| 1999 |
Hama H, Schnieders EA, Thorner J, Takemoto JY, DeWald DB. Direct involvement of phosphatidylinositol 4-phosphate in secretion in the yeast Saccharomyces cerevisiae. The Journal of Biological Chemistry. 274: 34294-300. PMID 10567405 DOI: 10.1074/Jbc.274.48.34294 |
0.426 |
|
| 1999 |
Hendricks KB, Wang BQ, Schnieders EA, Thorner J. Yeast homologue of neuronal frequenin is a regulator of phosphatidylinositol-4-OH kinase. Nature Cell Biology. 1: 234-41. PMID 10559922 DOI: 10.1038/12058 |
0.447 |
|
| 1999 |
Shulewitz MJ, Inouye CJ, Thorner J. Hsl7 localizes to a septin ring and serves as an adapter in a regulatory pathway that relieves tyrosine phosphorylation of Cdc28 protein kinase in Saccharomyces cerevisiae. Molecular and Cellular Biology. 19: 7123-37. PMID 10490648 DOI: 10.1128/Mcb.19.10.7123 |
0.839 |
|
| 1999 |
Casamayor A, Torrance PD, Kobayashi T, Thorner J, Alessi DR. Functional counterparts of mammalian protein kinases PDK1 and SGK in budding yeast. Current Biology : Cb. 9: 186-97. PMID 10074427 DOI: 10.1016/S0960-9822(99)80088-8 |
0.822 |
|
| 1998 |
Bardwell L, Cook JG, Zhu-Shimoni JX, Voora D, Thorner J. Differential regulation of transcription: repression by unactivated mitogen-activated protein kinase Kss1 requires the Dig1 and Dig2 proteins. Proceedings of the National Academy of Sciences of the United States of America. 95: 15400-5. PMID 9860980 DOI: 10.1073/Pnas.95.26.15400 |
0.472 |
|
| 1998 |
Bardwell L, Cook JG, Voora D, Baggott DM, Martinez AR, Thorner J. Repression of yeast Ste12 transcription factor by direct binding of unphosphorylated Kss1 MAPK and its regulation by the Ste7 MEK. Genes & Development. 12: 2887-98. PMID 9744865 DOI: 10.1101/Gad.12.18.2887 |
0.467 |
|
| 1998 |
Flick JS, Thorner J. An essential function of a phosphoinositide-specific phospholipase C is relieved by inhibition of a cyclin-dependent protein kinase in the yeast Saccharomyces cerevisiae. Genetics. 148: 33-47. PMID 9475719 |
0.388 |
|
| 1998 |
Thorner J. Genetic and biochemical characterization of ypk1 and ykr2, a pair of homologous protein kinases from saccharomyces cerevisiae Faseb Journal. 12: A1410. |
0.316 |
|
| 1997 |
Cook JG, Bardwell L, Thorner J. Inhibitory and activating functions for MAPK Kss1 in the S. cerevisiae filamentous-growth signalling pathway. Nature. 390: 85-8. PMID 9363895 DOI: 10.1038/36355 |
0.458 |
|
| 1997 |
Inouye C, Dhillon N, Durfee T, Zambryski PC, Thorner J. Mutational analysis of STE5 in the yeast Saccharomyces cerevisiae: application of a differential interaction trap assay for examining protein-protein interactions. Genetics. 147: 479-92. PMID 9335587 |
0.322 |
|
| 1997 |
Inouye C, Dhillon N, Thorner J. Ste5 RING-H2 domain: role in Ste4-promoted oligomerization for yeast pheromone signaling. Science (New York, N.Y.). 278: 103-6. PMID 9311911 DOI: 10.1126/science.278.5335.103 |
0.444 |
|
| 1997 |
Brazill DT, Thorner J, Martin GS. Mck1, a member of the glycogen synthase kinase 3 family of protein kinases, is a negative regulator of pyruvate kinase in the yeast Saccharomyces cerevisiae. Journal of Bacteriology. 179: 4415-8. PMID 9209064 DOI: 10.1128/Jb.179.13.4415-4418.1997 |
0.481 |
|
| 1997 |
David NE, Gee M, Andersen B, Naider F, Thorner J, Stevens RC. Expression and purification of the Saccharomyces cerevisiae alpha-factor receptor (Ste2p), a 7-transmembrane-segment G protein-coupled receptor. The Journal of Biological Chemistry. 272: 15553-61. PMID 9182592 DOI: 10.1074/Jbc.272.24.15553 |
0.336 |
|
| 1997 |
Wilson LK, Dhillon N, Thorner J, Martin GS. Casein kinase II catalyzes tyrosine phosphorylation of the yeast nucleolar immunophilin Fpr3. The Journal of Biological Chemistry. 272: 12961-7. PMID 9148902 DOI: 10.1074/jbc.272.20.12961 |
0.346 |
|
| 1997 |
Dohlman HG, Thorner J. RGS proteins and signaling by heterotrimeric G proteins. The Journal of Biological Chemistry. 272: 3871-4. PMID 9064301 DOI: 10.1074/Jbc.272.7.3871 |
0.621 |
|
| 1996 |
Melcher ML, Thorner J. Identification and characterization of the CLK1 gene product, a novel CaM kinase-like protein kinase from the yeast Saccharomyces cerevisiae. The Journal of Biological Chemistry. 271: 29958-68. PMID 8939941 DOI: 10.1074/jbc.271.47.29958 |
0.506 |
|
| 1996 |
Cook JG, Bardwell L, Kron SJ, Thorner J. Two novel targets of the MAP kinase Kss1 are negative regulators of invasive growth in the yeast Saccharomyces cerevisiae. Genes & Development. 10: 2831-48. PMID 8918885 DOI: 10.1101/Gad.10.22.2831 |
0.5 |
|
| 1996 |
Bardwell L, Thorner J. A conserved motif at the amino termini of MEKs might mediate high-affinity interaction with the cognate MAPKs. Trends in Biochemical Sciences. 21: 373-4. PMID 8918190 DOI: 10.1016/S0968-0004(96)30032-7 |
0.319 |
|
| 1996 |
Dhillon N, Thorner J. Immunophilins in the Yeast Saccharomyces cerevisiae: A Different Spin on Proline Rotamases Methods (San Diego, Calif.). 9: 165-76. PMID 8812661 DOI: 10.1006/meth.1996.0023 |
0.414 |
|
| 1996 |
Dohlman HG, Song J, Ma D, Courchesne WE, Thorner J. Sst2, a negative regulator of pheromone signaling in the yeast Saccharomyces cerevisiae: expression, localization, and genetic interaction and physical association with Gpa1 (the G-protein alpha subunit). Molecular and Cellular Biology. 16: 5194-209. PMID 8756677 DOI: 10.1128/Mcb.16.9.5194 |
0.708 |
|
| 1996 |
Bardwell L, Cook JG, Chang EC, Cairns BR, Thorner J. Signaling in the yeast pheromone response pathway: specific and high-affinity interaction of the mitogen-activated protein (MAP) kinases Kss1 and Fus3 with the upstream MAP kinase kinase Ste7. Molecular and Cellular Biology. 16: 3637-50. PMID 8668180 DOI: 10.1128/Mcb.16.7.3637 |
0.494 |
|
| 1996 |
Swartzman EE, Viswanathan MN, Thorner J. The PAL1 gene product is a peroxisomal ATP-binding cassette transporter in the yeast Saccharomyces cerevisiae. The Journal of Cell Biology. 132: 549-63. PMID 8647887 DOI: 10.1083/jcb.132.4.549 |
0.422 |
|
| 1995 |
Jiang W, Lim MY, Yoon HJ, Thorner J, Martin GS, Carbon J. Overexpression of the yeast MCK1 protein kinase suppresses conditional mutations in centromere-binding protein genes CBF2 and CBF5. Molecular & General Genetics : Mgg. 246: 360-6. PMID 7854321 DOI: 10.1007/BF00288609 |
0.482 |
|
| 1995 |
Harris E, Yaswen P, Thorner J. Gain-of-function mutations in a human calmodulin-like protein identify residues critical for calmodulin action in yeast. Molecular & General Genetics : Mgg. 247: 137-47. PMID 7753022 DOI: 10.1007/Bf00705643 |
0.559 |
|
| 1995 |
Ma D, Cook JG, Thorner J. Phosphorylation and localization of Kss1, a MAP kinase of the Saccharomyces cerevisiae pheromone response pathway. Molecular Biology of the Cell. 6: 889-909. PMID 7579701 DOI: 10.1091/Mbc.6.7.889 |
0.503 |
|
| 1995 |
Wilson LK, Benton BM, Zhou S, Thorner J, Martin GS. The yeast immunophilin Fpr3 is a physiological substrate of the tyrosine-specific phosphoprotein phosphatase Ptp1. The Journal of Biological Chemistry. 270: 25185-93. PMID 7559654 DOI: 10.1074/Jbc.270.42.25185 |
0.507 |
|
| 1994 |
Hasson MS, Blinder D, Thorner J, Jenness DD. Mutational activation of the STE5 gene product bypasses the requirement for G protein beta and gamma subunits in the yeast pheromone response pathway. Molecular and Cellular Biology. 14: 1054-65. PMID 8289786 DOI: 10.1128/Mcb.14.2.1054 |
0.434 |
|
| 1994 |
Florio M, Wilson LK, Trager JB, Thorner J, Martin GS. Aberrant protein phosphorylation at tyrosine is responsible for the growth-inhibitory action of pp60v-src expressed in the yeast Saccharomyces cerevisiae. Molecular Biology of the Cell. 5: 283-96. PMID 8049521 DOI: 10.1091/Mbc.5.3.283 |
0.482 |
|
| 1994 |
Salama SR, Hendricks KB, Thorner J. G1 cyclin degradation: the PEST motif of yeast Cln2 is necessary, but not sufficient, for rapid protein turnover. Molecular and Cellular Biology. 14: 7953-66. PMID 7969135 DOI: 10.1128/Mcb.14.12.7953 |
0.504 |
|
| 1994 |
Auble DT, Hansen KE, Mueller CG, Lane WS, Thorner J, Hahn S. Mot1, a global repressor of RNA polymerase II transcription, inhibits TBP binding to DNA by an ATP-dependent mechanism. Genes & Development. 8: 1920-34. PMID 7958867 DOI: 10.1101/Gad.8.16.1920 |
0.354 |
|
| 1994 |
Bardwell L, Cook JG, Inouye CJ, Thorner J. Signal propagation and regulation in the mating pheromone response pathway of the yeast Saccharomyces cerevisiae. Developmental Biology. 166: 363-79. PMID 7813763 DOI: 10.1006/Dbio.1994.1323 |
0.43 |
|
| 1994 |
Benton BM, Zang JH, Thorner J. A novel FK506- and rapamycin-binding protein (FPR3 gene product) in the yeast Saccharomyces cerevisiae is a proline rotamase localized to the nucleolus. The Journal of Cell Biology. 127: 623-39. PMID 7525596 DOI: 10.1083/jcb.127.3.623 |
0.333 |
|
| 1994 |
Kuchler K, Swartzman EE, Thorner J. A Novel mechanism for transmembrane translocation of peptides: The Saccharomyces cerevisiae STE6 Transporter and export of the mating pheromone a-factor Current Topics in Membranes. 41: 19-42. DOI: 10.1016/S0070-2161(08)60452-9 |
0.4 |
|
| 1993 |
Dohlman HG, Goldsmith P, Spiegel AM, Thorner J. Pheromone action regulates G-protein alpha-subunit myristoylation in the yeast Saccharomyces cerevisiae. Proceedings of the National Academy of Sciences of the United States of America. 90: 9688-92. PMID 8415763 DOI: 10.1073/Pnas.90.20.9688 |
0.638 |
|
| 1993 |
Lim MY, Dailey D, Martin GS, Thorner J. Yeast MCK1 protein kinase autophosphorylates at tyrosine and serine but phosphorylates exogenous substrates at serine and threonine. The Journal of Biological Chemistry. 268: 21155-64. PMID 8407952 |
0.384 |
|
| 1993 |
Flick JS, Thorner J. Genetic and biochemical characterization of a phosphatidylinositol-specific phospholipase C in Saccharomyces cerevisiae. Molecular and Cellular Biology. 13: 5861-76. PMID 8395015 DOI: 10.1128/Mcb.13.9.5861 |
0.389 |
|
| 1993 |
Flanagan CA, Schnieders EA, Emerick AW, Kunisawa R, Admon A, Thorner J. Phosphatidylinositol 4-kinase: gene structure and requirement for yeast cell viability. Science (New York, N.Y.). 262: 1444-8. PMID 8248783 DOI: 10.1126/Science.8248783 |
0.449 |
|
| 1993 |
Kuchler K, Dohlman HG, Thorner J. The a-factor transporter (STE6 gene product) and cell polarity in the yeast Saccharomyces cerevisiae. The Journal of Cell Biology. 120: 1203-15. PMID 7679674 DOI: 10.1083/Jcb.120.5.1203 |
0.638 |
|
| 1992 |
Gimble FS, Thorner J. Homing of a DNA endonuclease gene by meiotic gene conversion in Saccharomyces cerevisiae. Nature. 357: 301-6. PMID 1534148 DOI: 10.1038/357301A0 |
0.312 |
|
| 1992 |
Kuchler K, Thorner J. Secretion of peptides and proteins lacking hydrophobic signal sequences: the role of adenosine triphosphate-driven membrane translocators. Endocrine Reviews. 13: 499-514. PMID 1425485 DOI: 10.1210/edrv-13-3-499 |
0.378 |
|
| 1992 |
Kuchler K, Thorner J. Functional expression of human mdr1 in the yeast Saccharomyces cerevisiae. Proceedings of the National Academy of Sciences of the United States of America. 89: 2302-6. PMID 1347948 DOI: 10.1073/Pnas.89.6.2302 |
0.364 |
|
| 1992 |
Flanagan CA, Thorner J. Purification and characterization of a soluble phosphatidylinositol 4-kinase from the yeast Saccharomyces cerevisiae. The Journal of Biological Chemistry. 267: 24117-25. PMID 1331109 |
0.321 |
|
| 1992 |
Cyert MS, Thorner J. Regulatory subunit (CNB1 gene product) of yeast Ca2+/calmodulin-dependent phosphoprotein phosphatases is required for adaptation to pheromone. Molecular and Cellular Biology. 12: 3460-9. PMID 1321337 DOI: 10.1128/MCB.12.8.3460 |
0.708 |
|
| 1992 |
Davis JL, Kunisawa R, Thorner J. A presumptive helicase (MOT1 gene product) affects gene expression and is required for viability in the yeast Saccharomyces cerevisiae. Molecular and Cellular Biology. 12: 1879-92. PMID 1312673 DOI: 10.1128/Mcb.12.4.1879 |
0.353 |
|
| 1991 |
Pausch MH, Kaim D, Kunisawa R, Admon A, Thorner J. Multiple Ca2+/calmodulin-dependent protein kinase genes in a unicellular eukaryote. The Embo Journal. 10: 1511-22. PMID 2026147 DOI: 10.1002/J.1460-2075.1991.Tb07671.X |
0.457 |
|
| 1991 |
Blumer KJ, Thorner J. Receptor-G protein signaling in yeast. Annual Review of Physiology. 53: 37-57. PMID 1904209 DOI: 10.1146/Annurev.Ph.53.030191.000345 |
0.409 |
|
| 1991 |
Fields FO, Thorner J. Genetic suppression analysis of the function of a protein kinase C (PKC1 gene product) in Saccharomyces cerevisiae cell cycle progression: the SKCd mutations. Cold Spring Harbor Symposia On Quantitative Biology. 56: 51-60. PMID 1819504 DOI: 10.1101/Sqb.1991.056.01.008 |
0.43 |
|
| 1991 |
Dohlman HG, Thorner J, Caron MG, Lefkowitz RJ. Model systems for the study of seven-transmembrane-segment receptors. Annual Review of Biochemistry. 60: 653-88. PMID 1652922 DOI: 10.1146/annurev.bi.60.070191.003253 |
0.646 |
|
| 1991 |
Cyert MS, Kunisawa R, Kaim D, Thorner J. Yeast has homologs (CNA1 and CNA2 gene products) of mammalian calcineurin, a calmodulin-regulated phosphoprotein phosphatase. Proceedings of the National Academy of Sciences of the United States of America. 88: 7376-80. PMID 1651503 DOI: 10.1073/pnas.88.16.7376 |
0.693 |
|
| 1990 |
Bresnahan PA, Leduc R, Thomas L, Thorner J, Gibson HL, Brake AJ, Barr PJ, Thomas G. Human fur gene encodes a yeast KEX2-like endoprotease that cleaves pro-beta-NGF in vivo. The Journal of Cell Biology. 111: 2851-9. PMID 2269657 DOI: 10.1083/Jcb.111.6.2851 |
0.336 |
|
| 1990 |
Kuchler K, Thorner J. Membrane translocation of proteins without hydrophobic signal peptides. Current Opinion in Cell Biology. 2: 617-24. PMID 2252588 DOI: 10.1016/0955-0674(90)90102-K |
0.324 |
|
| 1990 |
Levin DE, Fields FO, Kunisawa R, Bishop JM, Thorner J. A candidate protein kinase C gene, PKC1, is required for the S. cerevisiae cell cycle. Cell. 62: 213-24. PMID 2196995 DOI: 10.1016/0092-8674(90)90360-Q |
0.493 |
|
| 1990 |
King K, Dohlman HG, Thorner J, Caron MG, Lefkowitz RJ. Control of yeast mating signal transduction by a mammalian beta 2-adrenergic receptor and Gs alpha subunit. Science (New York, N.Y.). 250: 121-3. PMID 2171146 DOI: 10.1126/Science.2171146 |
0.65 |
|
| 1990 |
Blumer KJ, Thorner J. Beta and gamma subunits of a yeast guanine nucleotide-binding protein are not essential for membrane association of the alpha subunit but are required for receptor coupling. Proceedings of the National Academy of Sciences of the United States of America. 87: 4363-7. PMID 2161538 DOI: 10.1073/Pnas.87.11.4363 |
0.362 |
|
| 1990 |
Dailey D, Schieven GL, Lim MY, Marquardt H, Gilmore T, Thorner J, Martin GS. Novel yeast protein kinase (YPK1 gene product) is a 40-kilodalton phosphotyrosyl protein associated with protein-tyrosine kinase activity. Molecular and Cellular Biology. 10: 6244-56. PMID 1701015 DOI: 10.1128/Mcb.10.12.6244 |
0.47 |
|
| 1989 |
Kuchler K, Sterne RE, Thorner J. Saccharomyces cerevisiae STE6 gene product: a novel pathway for protein export in eukaryotic cells. The Embo Journal. 8: 3973-84. PMID 2686977 DOI: 10.1002/J.1460-2075.1989.Tb08580.X |
0.408 |
|
| 1989 |
Fuller RS, Brake AJ, Thorner J. Intracellular targeting and structural conservation of a prohormone-processing endoprotease. Science (New York, N.Y.). 246: 482-6. PMID 2683070 DOI: 10.1126/Science.2683070 |
0.64 |
|
| 1989 |
Courchesne WE, Kunisawa R, Thorner J. A putative protein kinase overcomes pheromone-induced arrest of cell cycling in S. cerevisiae. Cell. 58: 1107-19. PMID 2673544 DOI: 10.1016/0092-8674(89)90509-6 |
0.478 |
|
| 1989 |
Fuller RS, Brake A, Thorner J. Yeast prohormone processing enzyme (KEX2 gene product) is a Ca2+-dependent serine protease. Proceedings of the National Academy of Sciences of the United States of America. 86: 1434-8. PMID 2646633 DOI: 10.1073/Pnas.86.5.1434 |
0.61 |
|
| 1989 |
Schafer WR, Kim R, Sterne R, Thorner J, Kim SH, Rine J. Genetic and pharmacological suppression of oncogenic mutations in ras genes of yeast and humans. Science (New York, N.Y.). 245: 379-85. PMID 2569235 DOI: 10.1126/Science.2569235 |
0.345 |
|
| 1989 |
Davis TN, Thorner J. Vertebrate and yeast calmodulin, despite significant sequence divergence, are functionally interchangeable. Proceedings of the National Academy of Sciences of the United States of America. 86: 7909-13. PMID 2554295 DOI: 10.1073/Pnas.86.20.7909 |
0.412 |
|
| 1989 |
Cyert MS, Thorner J. Putting it on and taking it off: phosphoprotein phosphatase involvement in cell cycle regulation. Cell. 57: 891-3. PMID 2544293 DOI: 10.1016/0092-8674(89)90325-5 |
0.69 |
|
| 1989 |
Foster R, Thorner J, Martin GS. Nucleotidylation, not phosphorylation, is the major source of the phosphotyrosine detected in enteric bacteria. Journal of Bacteriology. 171: 272-9. PMID 2464577 DOI: 10.1128/Jb.171.1.272-279.1989 |
0.43 |
|
| 1988 |
Thomas G, Thorne BA, Thomas L, Allen RG, Hruby DE, Fuller R, Thorner J. Yeast KEX2 endopeptidase correctly cleaves a neuroendocrine prohormone in mammalian cells. Science (New York, N.Y.). 241: 226-30. PMID 3291117 DOI: 10.1126/Science.3291117 |
0.598 |
|
| 1988 |
Fuller RS, Sterne RE, Thorner J. Enzymes required for yeast prohormone processing. Annual Review of Physiology. 50: 345-62. PMID 3288097 DOI: 10.1146/annurev.ph.50.030188.002021 |
0.579 |
|
| 1988 |
Reneke JE, Blumer KJ, Courchesne WE, Thorner J. The carboxy-terminal segment of the yeast alpha-factor receptor is a regulatory domain. Cell. 55: 221-34. PMID 2844413 DOI: 10.1016/0092-8674(88)90045-1 |
0.351 |
|
| 1987 |
Kunisawa R, Davis TN, Urdea MS, Thorner J. Complete nucleotide sequence of the gene encoding the regulatory subunit of 3',5'-cyclic AMP-dependent protein kinase from the yeast Saccharomyces cerevisiae. Nucleic Acids Research. 15: 368-9. PMID 3547325 DOI: 10.1093/nar/15.1.368 |
0.451 |
|
| 1987 |
Van Arsdell SW, Stetler GL, Thorner J. The yeast repeated element sigma contains a hormone-inducible promoter. Molecular and Cellular Biology. 7: 749-59. PMID 3547081 DOI: 10.1128/Mcb.7.2.749 |
0.31 |
|
| 1987 |
Whiteway M, Freedman R, Van Arsdell S, Szostak JW, Thorner J. The yeast ARD1 gene product is required for repression of cryptic mating-type information at the HML locus. Molecular and Cellular Biology. 7: 3713-22. PMID 3316986 DOI: 10.1128/Mcb.7.10.3713 |
0.367 |
|
| 1986 |
Davis TN, Urdea MS, Masiarz FR, Thorner J. Isolation of the yeast calmodulin gene: calmodulin is an essential protein. Cell. 47: 423-31. PMID 3533275 DOI: 10.1016/0092-8674(86)90599-4 |
0.366 |
|
| 1986 |
Barnes DA, Thorner J. Genetic manipulation of Saccharomyces cerevisiae by use of the LYS2 gene. Molecular and Cellular Biology. 6: 2828-38. PMID 3023949 DOI: 10.1128/Mcb.6.8.2828 |
0.318 |
|
| 1986 |
Schieven G, Thorner J, Martin GS. Protein-tyrosine kinase activity in Saccharomyces cerevisiae. Science (New York, N.Y.). 231: 390-3. PMID 2417318 DOI: 10.1126/Science.2417318 |
0.463 |
|
| 1985 |
Thorner J. Pheromone-processing protease of the yeast Saccharomyces cerevisiae. Nature. 314: 384-5. PMID 3885046 DOI: 10.1038/314384a0 |
0.303 |
|
| 1984 |
Julius D, Brake A, Blair L, Kunisawa R, Thorner J. Isolation of the putative structural gene for the lysine-arginine-cleaving endopeptidase required for processing of yeast prepro-alpha-factor. Cell. 37: 1075-89. PMID 6430565 DOI: 10.1016/0092-8674(84)90442-2 |
0.583 |
|
| 1984 |
Julius D, Schekman R, Thorner J. Glycosylation and processing of prepro-alpha-factor through the yeast secretory pathway. Cell. 36: 309-18. PMID 6420074 DOI: 10.1016/0092-8674(84)90224-1 |
0.676 |
|
| 1984 |
Stetler GL, Thorner J. Molecular cloning of hormone-responsive genes from the yeast Saccharomyces cerevisiae. Proceedings of the National Academy of Sciences of the United States of America. 81: 1144-8. PMID 6366798 DOI: 10.1073/Pnas.81.4.1144 |
0.322 |
|
| 1983 |
Emr SD, Schekman R, Flessel MC, Thorner J. An MF alpha 1-SUC2 (alpha-factor-invertase) gene fusion for study of protein localization and gene expression in yeast. Proceedings of the National Academy of Sciences of the United States of America. 80: 7080-4. PMID 6359161 DOI: 10.1073/Pnas.80.23.7080 |
0.535 |
|
| 1983 |
Sprague GF, Blair LC, Thorner J. Cell interactions and regulation of cell type in the yeast Saccharomyces cerevisiae. Annual Review of Microbiology. 37: 623-60. PMID 6357062 DOI: 10.1146/annurev.mi.37.100183.003203 |
0.406 |
|
| 1983 |
Brake AJ, Julius DJ, Thorner J. A functional prepro-alpha-factor gene in Saccharomyces yeasts can contain three, four, or five repeats of the mature pheromone sequence. Molecular and Cellular Biology. 3: 1440-50. PMID 6353204 DOI: 10.1128/Mcb.3.8.1440 |
0.552 |
|
| 1983 |
Chan RK, Melnick LM, Blair LC, Thorner J. Extracellular suppression allows mating by pheromone-deficient sterile mutants of Saccharomyces cerevisiae. Journal of Bacteriology. 155: 903-6. PMID 6348031 DOI: 10.1128/Jb.155.2.903-906.1983 |
0.306 |
|
| 1983 |
Julius D, Blair L, Brake A, Sprague G, Thorner J. Yeast alpha factor is processed from a larger precursor polypeptide: the essential role of a membrane-bound dipeptidyl aminopeptidase. Cell. 32: 839-52. PMID 6339075 DOI: 10.1016/0092-8674(83)90070-3 |
0.55 |
|
| 1982 |
Bisson LF, Thorner J. Effect of halogenated pyrimidine 5'-mononucleotides on dTMP-permeable yeast strains and the isolation and characterization of resistant mutants. Molecular & General Genetics : Mgg. 186: 467-74. PMID 6752656 DOI: 10.1007/BF00337949 |
0.593 |
|
| 1982 |
Bisson LF, Thorner J. Exogenous dTMP utilization by a novel tup mutant of Saccharomyces cerevisiae. Journal of Bacteriology. 152: 111-9. PMID 6749802 |
0.546 |
|
| 1982 |
Bisson LF, Thorner J. Mutations in the pho80 gene confer permeability to 5'-mononucleotides in Saccharomyces cerevisiae. Genetics. 102: 341-59. PMID 6293915 |
0.578 |
|
| 1981 |
Bisson LF, Thorner J. Thymidylate synthetase from Saccharomyces cerevisiae. Purification and enzymic properties. The Journal of Biological Chemistry. 256: 12456-62. PMID 7028756 |
0.53 |
|
| 1981 |
Liao HH, Thorner J. Adenosine 3',5'-phosphate phosphodiesterase and pheromone response in the yeast Saccharomyces cerevisiae. Journal of Bacteriology. 148: 919-25. PMID 6171560 DOI: 10.1128/Jb.148.3.919-925.1981 |
0.378 |
|
| 1980 |
Liao H, Thorner J. Yeast mating pheromone alpha factor inhibits adenylate cyclase. Proceedings of the National Academy of Sciences of the United States of America. 77: 1898-902. PMID 6246513 DOI: 10.1073/Pnas.77.4.1898 |
0.33 |
|
| 1979 |
Ciejek E, Thorner J. Recovery of S. cerevisiae a cells from G1 arrest by alpha factor pheromone requires endopeptidase action. Cell. 18: 623-35. PMID 391400 DOI: 10.1016/0092-8674(79)90117-X |
0.32 |
|
| 1978 |
Baum P, Thorner J, Honig L. Identification of tubulin from the yeast Saccharomyces cerevisiae. Proceedings of the National Academy of Sciences of the United States of America. 75: 4962-6. PMID 368805 DOI: 10.1073/Pnas.75.10.4962 |
0.381 |
|
| 1978 |
Fehrenbacher G, Perry K, Thorner J. Cell-cell recognition in Saccharomyces cerevisiae: regulation of mating-specific adhesion. Journal of Bacteriology. 134: 893-901. PMID 350854 DOI: 10.1128/Jb.134.3.893-901.1978 |
0.353 |
|
| 1977 |
Bisson L, Thorner J. Thymidine 5'-monophosphate-requiring mutants of Saccharomyces cerevisiae are deficient in thymidylate synthetase. Journal of Bacteriology. 132: 44-50. PMID 334734 DOI: 10.1128/Jb.132.1.44-50.1977 |
0.633 |
|
| 1975 |
Thorner J, Huang WM, Lehman IR. Energy-dependent activation of the temperature-sensitive DNA polymerases induced by bacteriophage T4 gene 43 mutants. Virology. 68: 338-48. PMID 1198924 DOI: 10.1016/0042-6822(75)90277-9 |
0.536 |
|
| 1973 |
Thorner JW, Paulus H. Catalytic and allosteric properties of glycerol kinase from Escherichia coli. The Journal of Biological Chemistry. 248: 3922-32. PMID 4575199 |
0.541 |
|
| 1973 |
Thorner JW, Paulus H. 14 Glycerol and Glycerate Kinases Enzymes. 8: 487-508. DOI: 10.1016/S1874-6047(08)60074-8 |
0.568 |
|
| 1971 |
Thorner JW, Paulus H. Composition and subunit structure of glycerol kinase from Escherichia coli. The Journal of Biological Chemistry. 246: 3885-94. PMID 4934840 |
0.536 |
|
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