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Dirk Trauner, Ph.D. - Publications

Affiliations: 
2000-2008 Chemistry University of California, Berkeley, Berkeley, CA, United States 
 2008- Chemistry Ludwig-Maximilians-Universität München, München, Bayern, Germany 
Area:
Optochemcical Genetics, visual system, NMDA channels, glutamate receptors, ion channels, optogenetics
Website:
http://www.cup.uni-muenchen.de/oc/trauner/
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Year Citation  Score
2023 Vepřek NA, Cooper MH, Laprell L, Yang EJ, Folkerts S, Bao R, Oertner TG, Pon LA, Zuchero JB, Trauner DH. Optical Control of G-Actin with a Photoswitchable Latrunculin. Biorxiv : the Preprint Server For Biology. PMID 37502978 DOI: 10.1101/2023.07.17.549222  0.765
2023 Hartrampf N, Leitao SM, Winter N, Toombs-Ruane H, Frank JA, Schwille P, Trauner D, Franquelim HG. Structural Diversity of Photoswitchable Sphingolipids for Optodynamic Control of Lipid Microdomains. Biophysical Journal. PMID 36869591 DOI: 10.1016/j.bpj.2023.02.029  0.772
2022 Pritzl SD, Morstein J, Kahler S, Konrad DB, Trauner D, Lohmüller T. Postsynthetic Photocontrol of Giant Liposomes via Fusion-Based Photolipid Doping. Langmuir : the Acs Journal of Surfaces and Colloids. 38: 11941-11949. PMID 36130117 DOI: 10.1021/acs.langmuir.2c01685  0.718
2022 Konrad DB, Rühmann KP, Ando H, Hetzler BE, Strassner N, Houk KN, Matsuura BS, Trauner D. A concise synthesis of tetrodotoxin. Science (New York, N.Y.). 377: 411-415. PMID 35862530 DOI: 10.1126/science.abn0571  0.746
2022 Pritzl SD, Konrad DB, Ober MF, Richter AF, Frank JA, Nickel B, Trauner D, Lohmüller T. Optical Membrane Control with Red Light Enabled by Red-Shifted Photolipids. Langmuir : the Acs Journal of Surfaces and Colloids. 38: 385-393. PMID 34969246 DOI: 10.1021/acs.langmuir.1c02745  0.785
2021 Porth S, Bats JW, Trauner D, Giester G, Mulzer J. Insight into the Mechanism of the Saegusa Oxidation: Isolation of a Novel Palladium(0)-Tetraolefin Complex. Angewandte Chemie (International Ed. in English). 38: 2015-2016. PMID 34182691 DOI: 10.1002/(SICI)1521-3773(19990712)38:13/14<2015::AID-ANIE2015>3.0.CO;2-#  0.429
2021 Donthamsetti P, Konrad DB, Hetzler B, Fu Z, Trauner D, Isacoff EY. Selective Photoswitchable Allosteric Agonist of a G Protein-Coupled Receptor. Journal of the American Chemical Society. PMID 34115935 DOI: 10.1021/jacs.1c02586  0.718
2021 Fehrentz T, Huber FME, Hartrampf N, Bruegmann T, Frank JA, Fine NHF, Malan D, Danzl JG, Tikhonov DB, Sumser M, Sasse P, Hodson DJ, Zhorov BS, Klöcker N, Trauner D. Author Correction: Optical control of L-type Ca channels using a diltiazem photoswitch. Nature Chemical Biology. PMID 33514938 DOI: 10.1038/s41589-021-00744-3  0.766
2020 Pritzl SD, Urban P, Prasselsperger A, Konrad DB, Frank JA, Trauner D, Lohmüller T. Photolipid Bilayer Permeability is Controlled by Transient Pore Formation. Langmuir : the Acs Journal of Surfaces and Colloids. PMID 33143416 DOI: 10.1021/acs.langmuir.0c02229  0.778
2020 Scheidt HA, Kolocaj K, Konrad DB, Frank JA, Trauner D, Langosch D, Huster D. Light-induced lipid mixing implies a causal role of lipid splay in membrane fusion. Biochimica Et Biophysica Acta. Biomembranes. 1862: 183438. PMID 32781156 DOI: 10.1016/J.Bbamem.2020.183438  0.765
2020 Klaja O, Frank JA, Trauner D, Bondar AN. Potential energy function for a photo-switchable lipid molecule. Journal of Computational Chemistry. 41: 2336-2351. PMID 32749723 DOI: 10.1002/Jcc.26387  0.571
2020 Morstein J, Dacheux MA, Norman DD, Shemet A, Donthamsetti PC, Citir M, Frank J, Schultz C, Isacoff EY, Parrill AL, Tigyi GJ, Trauner D. Optical Control of Lysophosphatidic Acid Signaling. Journal of the American Chemical Society. PMID 32469525 DOI: 10.1021/Jacs.0C02154  0.545
2020 Konrad DB, Savasci G, Allmendinger L, Trauner D, Ochsenfeld C, Ali AM. Computational Design and Synthesis of a Deeply Red-Shifted and Bistable Azobenzene. Journal of the American Chemical Society. PMID 32207943 DOI: 10.1021/Jacs.9B10430  0.723
2020 Urban P, Pritzl SD, Ober MF, Dirscherl CF, Pernpeintner C, Konrad DB, Frank JA, Trauner D, Nickel B, Lohmueller T. A Lipid Photoswitch Controls Fluidity in Supported Bilayer Membranes. Langmuir : the Acs Journal of Surfaces and Colloids. PMID 32069411 DOI: 10.1021/Acs.Langmuir.9B02942  0.766
2020 Trauner D, Impastato AC. Synthesis of Photo-Caged ATP Synfacts. 16: 601. DOI: 10.1055/S-0040-1707485  0.322
2020 Trauner D, Novak AJE. Hindered Dialkyl Ether Synthesis Electrified Synfacts. 16: 93. DOI: 10.1055/S-0039-1691380  0.38
2020 Trauner D, Impastato AC, Shemet A. Discovery and Synthesis of Monastrol Synfacts. 16: 90. DOI: 10.1055/S-0039-1691378  0.373
2020 Klaja O, Frank JA, Trauner D, Bondar A. Cover Image Journal of Computational Chemistry. 41. DOI: 10.1002/jcc.25979  0.47
2019 Trauner D, Hartrampf N, Seki T, Baumann A, Watson P, Hoffmann-Röder A, Tsuji M, Veprek N, Hetzler B. Optical Control of Cytokine Production Using Photoswitchable Galactosylceramides. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 31788876 DOI: 10.1002/Chem.201905279  0.722
2019 Winter N, Trauner D. Synthesis of acremines A, B and F and studies on the bisacremines. Beilstein Journal of Organic Chemistry. 15: 2271-2276. PMID 31598179 DOI: 10.3762/Bjoc.15.219  0.301
2019 Maier MS, Hüll K, Reynders M, Matsuura BS, Leippe P, Ko T, Sch Auml Ffer L, Trauner D. An Oxidative Approach Enables Efficient Access to Cyclic Azobenzenes. Journal of the American Chemical Society. PMID 31584272 DOI: 10.1021/Jacs.9B08794  0.333
2019 Hüll K, Benster T, Manookin MB, Trauner D, Van Gelder RN, Laprell L. Photopharmacologic Vision Restoration Reduces Pathological Rhythmic Field Potentials in Blind Mouse Retina. Scientific Reports. 9: 13561. PMID 31537864 DOI: 10.1038/S41598-019-49999-W  0.767
2019 Novak AJE, Grigglestone C, Trauner D. A Biomimetic Synthesis Elucidates the Origin of Preuisolactone A. Journal of the American Chemical Society. PMID 31518120 DOI: 10.1021/Jacs.9B08892  0.357
2019 Trads J, Hüll K, Matsuura BS, Laprell L, Fehrentz T, Görldt N, Kozek KA, Weaver CD, Klöcker N, Barber DM, Trauner D. Sign Inversion in Photopharmacology: Incorporation of Cyclic Azobenzenes in Photoswitchable Potassium Channel Blockers and Openers. Angewandte Chemie (International Ed. in English). PMID 31441199 DOI: 10.1002/Anie.201905790  0.783
2019 Inoue M, Trauner D. In honor of Professor Samuel J. Danishefsky. The Journal of Antibiotics. 72: 324. PMID 31130728 DOI: 10.1038/S41429-019-0182-Z  0.463
2019 Morstein J, Hill RZ, Novak AJE, Feng S, Norman DD, Donthamsetti PC, Frank JA, Harayama T, Williams BM, Parrill AL, Tigyi GJ, Riezman H, Isacoff EY, Bautista DM, Trauner D. Optical control of sphingosine-1-phosphate formation and function. Nature Chemical Biology. PMID 31036923 DOI: 10.1038/S41589-019-0269-7  0.578
2019 Winter N, Rupcic Z, Stadler M, Trauner D. Synthesis and biological evaluation of (±)-hippolachnin and analogs. The Journal of Antibiotics. PMID 30979942 DOI: 10.1038/S41429-019-0176-X  0.322
2019 Kol M, Williams B, Toombs-Ruane H, Franquelim HG, Korneev S, Schroeer C, Schwille P, Trauner D, Holthuis JC, Frank JA. Optical manipulation of sphingolipid biosynthesis using photoswitchable ceramides. Elife. 8. PMID 30720434 DOI: 10.7554/Elife.43230  0.568
2019 Trauner D, Hetzler BE. Click Chemistry for the Synthesis of Azides Synfacts. 15: 1435. DOI: 10.1055/S-0039-1691124  0.375
2019 Trauner D, Shemet A. Synthesis of Nucleoside Oligophosphates: Quick and Not Dirty Synfacts. 15: 1438. DOI: 10.1055/S-0039-1691122  0.37
2019 Trauner D, Shemet A. Ethynylphosphonamidates in the Synthesis of Antibody–Drug Conjugates Synfacts. 15: 1189. DOI: 10.1055/S-0039-1690935  0.372
2019 Trauner D, Fischer C. The First Total Synthesis of Artemisinin (Qinghaosu) Synfacts. 15: 1067. DOI: 10.1055/S-0039-1690609  0.367
2019 Trauner D, Vepřek NA. Efficient Synthesis of the Heparin Anticoagulant Idraparinux Synfacts. 15: 1060. DOI: 10.1055/S-0039-1690604  0.327
2019 Trauner D, Shemet A. Synthesis of Fluorinated Nucleoside Analogs with Antiviral Activity Synfacts. 15: 1063. DOI: 10.1055/S-0039-1690601  0.34
2019 Trauner D, Shemet A. Palladium-Catalyzed Synthesis of Pyrimidine Nucleoside Analogs Synfacts. 15: 1059. DOI: 10.1055/S-0039-1690600  0.385
2019 Trauner D, Reynders M. Macrocycle Library Synthesis through Thiol-to-Amine Cyclization Synfacts. 15: 1314. DOI: 10.1055/S-0039-1690292  0.376
2019 Trauner D, Hetzler BE. HPLC-Free Synthesis of Nucleoside Triphosphates Synfacts. 15: 1312. DOI: 10.1055/S-0039-1690285  0.345
2019 Trauner D, Shemet A. Synthesis of the Smallest Cyclodextrins Synfacts. 15: 805. DOI: 10.1055/S-0039-1689764  0.369
2019 Trauner D, Hetzler B. Ring-Closing Metathesis in the Synthesis of Simeprevir Synfacts. 2019: 563. DOI: 10.1055/S-0037-1612506  0.334
2019 Trauner D, Maier M. Ethynylphosphonamidate-Cysteine Bioconjugation Synfacts. 2019: 561. DOI: 10.1055/S-0037-1612502  0.463
2019 Trauner D, Maier M. Synthesis of a cGAMP Analogue Synfacts. 15: 434. DOI: 10.1055/S-0037-1612408  0.58
2019 Trauner D, Maier M. A Glutathione-Labile Oligonucleotide Protecting Group Synfacts. 15: 443. DOI: 10.1055/S-0037-1612407  0.464
2019 Trauner D, Matsuura BS. Synthesis of ‘Stretched’ Isosteres of Saturated Nitrogen Heterocycles Synfacts. 15: 441. DOI: 10.1055/S-0037-1612398  0.365
2019 Trauner D, Reyes JR. Design and Synthesis of a Potent Spongistatin 1 Analogue Synfacts. 15: 306. DOI: 10.1055/S-0037-1612116  0.306
2019 Trauner D, Matsuura BS. Synthesis and Biological Evaluation of Macrocyclic Δ12-Prostaglandin J2 Analogues Synfacts. 15: 310. DOI: 10.1055/S-0037-1612114  0.339
2019 Trauner D, Shemet A. Protecting-Group Free Synthesis of (–)-Δ8-THC Derivatives Synfacts. 15: 313. DOI: 10.1055/S-0037-1612111  0.304
2018 Rizzo A, Mayer R, Trauner D. A Biomimetic Approach Towards Enterocin and Deoxyenterocin. The Journal of Organic Chemistry. PMID 30520624 DOI: 10.1021/Acs.Joc.8B02273  0.331
2018 Frank JA, Broichhagen J, Yushchenko DA, Trauner D, Schultz C, Hodson DJ. Optical tools for understanding the complexity of β-cell signalling and insulin release. Nature Reviews. Endocrinology. PMID 30356209 DOI: 10.1038/S41574-018-0105-2  0.534
2018 Urban P, Pritzl SD, Konrad DB, Frank JA, Pernpeintner C, Roeske CR, Trauner D, Lohmüller T. Light-Controlled Lipid Interaction and Membrane Organization in Photolipid Bilayer Vesicles. Langmuir : the Acs Journal of Surfaces and Colloids. PMID 30346771 DOI: 10.1021/Acs.Langmuir.8B03241  0.77
2018 Reyes J, Winter N, Spessert L, Trauner D. Biomimetic Synthesis of (+)-Aspergillin PZ. Angewandte Chemie (International Ed. in English). PMID 30239081 DOI: 10.1002/Anie.201809703  0.348
2018 Durand-de Cuttoli R, Mondoloni S, Marti F, Lemoine D, Nguyen C, Naudé J, d'Izarny-Gargas T, Pons S, Maskos U, Trauner D, Kramer RH, Faure P, Mourot A. Manipulating midbrain dopamine neurons and reward-related behaviors with light-controllable nicotinic acetylcholine receptors. Elife. 7. PMID 30176987 DOI: 10.7554/Elife.37487  0.496
2018 Hetzler B, Volpin G, Vignoni E, Proni G, Petrovic A, Hu C, Trauner D. A versatile bis-allylboron reagent for the stereoselective synthesis of chiral diols. Angewandte Chemie (International Ed. in English). PMID 30144261 DOI: 10.1002/Anie.201808234  0.378
2018 Fehrentz T, Huber FME, Hartrampf N, Bruegmann T, Frank JA, Fine NHF, Malan D, Danzl JG, Tikhonov DB, Sumser M, Sasse P, Hodson DJ, Zhorov BS, Klöcker N, Trauner D. Optical control of L-type Ca channels using a diltiazem photoswitch. Nature Chemical Biology. PMID 30013061 DOI: 10.1038/S41589-018-0090-8  0.781
2018 Leippe P, Winter N, Sumser M, Trauner D. Optical Control of a Delayed Rectifier and a Two-Pore Potassium Channel with a Photoswitchable Bupivacaine. Acs Chemical Neuroscience. PMID 30001098 DOI: 10.1021/Acschemneuro.8B00279  0.313
2018 Hüll K, Morstein J, Trauner D. In Vivo Photopharmacology. Chemical Reviews. PMID 29985590 DOI: 10.1021/Acs.Chemrev.8B00037  0.313
2018 Cheng B, Volpin G, Morstein J, Trauner D. Total Synthesis of (±)-Exotine B. Organic Letters. PMID 29978703 DOI: 10.1021/Acs.Orglett.8B01817  0.37
2018 Hartrampf N, Winter N, Pupo G, Stoltz BM, Trauner D. Total Synthesis of the Norhasubanan Alkaloid Stephadiamine. Journal of the American Chemical Society. PMID 29889502 DOI: 10.1021/Jacs.8B01918  0.762
2018 Rizzo A, Trauner D. Toward (-)-Enterocin: An Improved Cuprate Barbier Protocol To Overcome Strain and Sterical Hindrance. Organic Letters. PMID 29553746 DOI: 10.1021/Acs.Orglett.8B00353  0.333
2018 Berry MH, Holt A, Levitz J, Broichhagen J, Gaub BM, Visel M, Stanley C, Aghi K, Kim YJ, Cao K, Kramer RH, Trauner D, Flannery J, Isacoff EY. Author Correction: Restoration of patterned vision with an engineered photoactivatable G protein-coupled receptor. Nature Communications. 9: 1112. PMID 29535310 DOI: 10.1038/S41467-018-03585-2  0.477
2018 Williams BM, Trauner D. An Azomethine Ylide Cycloaddition Approach towards Dendrobine: Synthesis of 5-Deoxymubironine C. The Journal of Organic Chemistry. PMID 29490142 DOI: 10.1021/Acs.Joc.8B00192  0.346
2018 Terwilliger DW, Trauner D. Selectivity in Diversity: Total Synthesis of Divergolide I. Journal of the American Chemical Society. PMID 29376358 DOI: 10.1021/Jacs.7B13092  0.356
2018 Cuttoli RD, Mondoloni S, Marti F, Lemoine D, Nguyen C, Naudé J, d'Izarny-Gargas T, Pons S, Maskos U, Trauner D, Kramer RH, Faure P, Mourot A. Author response: Manipulating midbrain dopamine neurons and reward-related behaviors with light-controllable nicotinic acetylcholine receptors Elife. DOI: 10.7554/Elife.37487.021  0.494
2018 Konrad D, Kicin B, Trauner D. Concise Asymmetric Synthesis of Kweichowenol A Synlett. 30: 383-386. DOI: 10.1055/S-0037-1610390  0.768
2018 Kolocaj K, Scheidt HA, Frank JA, Trauner D, Huster D, Langosch D. Should I Splay or Should I Stay - How Lipids and Transmembrane Helices Determine Membrane Fusion Biophysical Journal. 114: 605a. DOI: 10.1016/J.Bpj.2017.11.3310  0.536
2017 Frank JA, Yushchenko DA, Fine NHF, Duca M, Citir M, Broichhagen J, Hodson DJ, Schultz C, Trauner D. Optical control of GPR40 signalling in pancreatic β-cells. Chemical Science. 8: 7604-7610. PMID 29568424 DOI: 10.1039/C7Sc01475A  0.585
2017 Leinders-Zufall T, Storch U, Bleymehl K, Mederos Y Schnitzler M, Frank JA, Konrad DB, Trauner D, Gudermann T, Zufall F. PhoDAGs Enable Optical Control of Diacylglycerol-Sensitive Transient Receptor Potential Channels. Cell Chemical Biology. PMID 29276045 DOI: 10.1016/J.Chembiol.2017.11.008  0.791
2017 Westphal M, Schafroth MA, Sarott R, Imhof M, Bold C, Leippe P, Dhopeshwarkar A, Grandner J, Katritch V, Mackie K, Trauner D, Carreira EM, Frank JA. Synthesis of Photoswitchable Δ(9)-Tetrahydrocannabinol Derivatives Enables Optical Control of Cannabinoid Receptor 1 Signaling. Journal of the American Chemical Society. PMID 29161035 DOI: 10.1021/Jacs.7B06456  0.566
2017 Westphal M, Schafroth MA, Sarott R, Imhof M, Bold C, Leippe P, Dhopeshwarkar A, Grandner J, Katritch V, Mackie K, Trauner D, Carreira EM, Frank JA. Synthesis of Photoswitchable Δ(9)-Tetrahydrocannabinol Derivatives Enables Optical Control of Cannabinoid Receptor 1 Signaling. Journal of the American Chemical Society. PMID 29161035 DOI: 10.1021/Jacs.7B06456  0.566
2017 Bihelovic F, Stichnoth D, Müller R, Trauner D, Surup F. A Synthesis of Crocagin A. Angewandte Chemie (International Ed. in English). PMID 28812331 DOI: 10.1002/Anie.201612641  0.36
2017 Winter N, Trauner D. Thiocarbonyl Ylide Chemistry Enables a Concise Synthesis of (±)-Hippolachnin A. Journal of the American Chemical Society. PMID 28753024 DOI: 10.1021/Jacs.7B06815  0.304
2017 Trauner D, Schmid M. Biomimetic Synthesis of Complex Flavonoids Isolated From Daemonorops "Dragon's Blood". Angewandte Chemie (International Ed. in English). PMID 28736831 DOI: 10.1002/Anie.201705390  0.314
2017 Trauner D, Cheng B, Müller R. Total Syntheses of Cystobactamids and Structural Confirmation of Cystobactamid 919-2. Angewandte Chemie (International Ed. in English). PMID 28731542 DOI: 10.1002/Anie.201705387  0.327
2017 Hartrampf FWW, Trauner D. Total Synthesis of Lycopladine A and Carinatine A via a Base-mediated Carbocyclization. The Journal of Organic Chemistry. PMID 28671469 DOI: 10.1021/Acs.Joc.7B00908  0.365
2017 Podewin T, Broichhagen J, Frost C, Groneberg D, Ast J, Meyer-Berg H, Fine NHF, Friebe A, Zacharias M, Hodson DJ, Trauner D, Hoffmann-Röder A. Optical control of a receptor-linked guanylyl cyclase using a photoswitchable peptidic hormone. Chemical Science. 8: 4644-4653. PMID 28626572 DOI: 10.1039/C6Sc05044A  0.308
2017 Liu SA, Trauner D. Asymmetric Synthesis of the Antiviral Diterpene Wickerol A. Journal of the American Chemical Society. PMID 28625047 DOI: 10.1021/Jacs.7B05046  0.33
2017 Laprell L, Tochitsky I, Kaur K, Manookin MB, Stein M, Barber DM, Schön C, Michalakis S, Biel M, Kramer RH, Sumser MP, Trauner D, Van Gelder RN. Photopharmacological control of bipolar cells restores visual function in blind mice. The Journal of Clinical Investigation. PMID 28581442 DOI: 10.1172/Jci92156  0.771
2017 Levitz J, Broichhagen J, Leippe P, Konrad D, Trauner D, Isacoff EY. Dual optical control and mechanistic insights into photoswitchable group II and III metabotropic glutamate receptors. Proceedings of the National Academy of Sciences of the United States of America. PMID 28396447 DOI: 10.1073/Pnas.1619652114  0.745
2017 Pernpeintner C, Frank JA, Urban P, Roeske CR, Pritzl S, Trauner D, Lohmueller T. Light-Controlled Membrane Mechanics and Shape Transitions of Photoswitchable Lipid Vesicles. Langmuir : the Acs Journal of Surfaces and Colloids. PMID 28361538 DOI: 10.1021/Acs.Langmuir.7B01020  0.563
2017 Ketels M, Konrad DB, Karaghiosoff K, Trauner D, Knochel P. Selective Lithiation, Magnesiation, and Zincation of Unsymmetrical Azobenzenes Using Continuous Flow. Organic Letters. PMID 28296419 DOI: 10.1021/Acs.Orglett.7B00460  0.718
2017 Hao HD, Trauner D. Furans as Versatile Synthons: Total Syntheses of Caribenol A and Caribenol B. Journal of the American Chemical Society. PMID 28218534 DOI: 10.1021/Jacs.7B00234  0.796
2017 Matsuura BS, Kölle P, Trauner D, de Vivie-Riedle R, Meier R. Unravelling Photochemical Relationships Among Natural Products from Aplysia dactylomela. Acs Central Science. 3: 39-46. PMID 28149951 DOI: 10.1021/Acscentsci.6B00293  0.32
2016 Barber DM, Schönberger M, Burgstaller J, Levitz J, Weaver CD, Isacoff EY, Baier H, Trauner D. Optical control of neuronal activity using a light-operated GIRK channel opener (LOGO). Chemical Science. 7: 2347-2352. PMID 28090283 DOI: 10.1039/C5Sc04084A  0.324
2016 Hartrampf FW, Furukawa T, Trauner D. A Conia-Ene-Type Cyclization under Basic Conditions Enables an Efficient Synthesis of (-)-Lycoposerramine R. Angewandte Chemie (International Ed. in English). PMID 28000374 DOI: 10.1002/Anie.201610021  0.328
2016 Volpin G, Vepřek NA, Bellan AB, Trauner D. Enantioselective Synthesis and Racemization of (-)-Sinoracutine. Angewandte Chemie (International Ed. in English). PMID 27990734 DOI: 10.1002/Anie.201608206  0.363
2016 Trads JB, Burgstaller J, Laprell L, Konrad DB, de la Osa de la Rosa L, Weaver CD, Baier H, Trauner D, Barber DM. Optical control of GIRK channels using visible light. Organic & Biomolecular Chemistry. PMID 27901161 DOI: 10.1039/C6Ob02153K  0.786
2016 Frank JA, Franquelim HG, Schwille P, Trauner D. Optical Control of Lipid Rafts with Photoswitchable Ceramides. Journal of the American Chemical Society. PMID 27626130 DOI: 10.1021/Jacs.6B07278  0.574
2016 Frank JA, Yushchenko DA, Hodson DJ, Lipstein N, Nagpal J, Rutter GA, Rhee JS, Gottschalk A, Brose N, Schultz C, Trauner D. Photoswitchable diacylglycerols enable optical control of protein kinase C. Nature Chemical Biology. PMID 27454932 DOI: 10.1038/Nchembio.2141  0.709
2016 Meier R, Trauner D. A Synthesis of (±)-Aplydactone. Angewandte Chemie (International Ed. in English). PMID 27356849 DOI: 10.1002/Anie.201604102  0.347
2016 Broichhagen J, Johnston NR, von Ohlen Y, Meyer-Berg H, Jones BJ, Bloom SR, Rutter GA, Trauner D, Hodson DJ. Allosteric Optical Control of a Class B G-Protein-Coupled Receptor. Angewandte Chemie (International Ed. in English). PMID 27059784 DOI: 10.1002/Anie.201600957  0.316
2016 Konrad DB, Frank JA, Trauner D. Synthesis of Redshifted Azobenzene Photoswitches by Late-Stage Functionalization. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 26889884 DOI: 10.1002/Chem.201505061  0.808
2016 Williams BM, Trauner D. Expedient Synthesis of (+)-Lycopalhine A. Angewandte Chemie (International Ed. in English). PMID 26748762 DOI: 10.1002/Anie.201509602  0.345
2016 Trauner D. Controlling Biological Pathways with Photopharmacology Biophysical Journal. 110: 364a. DOI: 10.1016/J.Bpj.2015.11.1964  0.31
2015 Broichhagen J, Damijonaitis A, Levitz J, Sokol KR, Leippe P, Konrad D, Isacoff EY, Trauner D. Orthogonal Optical Control of a G Protein-Coupled Receptor with a SNAP-Tethered Photochromic Ligand. Acs Central Science. 1: 383-93. PMID 27162996 DOI: 10.1021/Acscentsci.5B00260  0.745
2015 Hager A, Vrielink N, Hager D, Lefranc J, Trauner D. Synthetic approaches towards alkaloids bearing α-tertiary amines. Natural Product Reports. PMID 26621771 DOI: 10.1039/C5Np00096C  0.313
2015 Laprell L, Hüll K, Stawski P, Schön C, Michalakis S, Biel M, Sumser MP, Trauner D. Restoring Light Sensitivity in Blind Retinae Using a Photochromic AMPA Receptor Agonist. Acs Chemical Neuroscience. PMID 26495755 DOI: 10.1021/Acschemneuro.5B00234  0.774
2015 Ellerbrock P, Armanino N, Ilg MK, Webster R, Trauner D. An eight-step synthesis of epicolactone reveals its biosynthetic origin. Nature Chemistry. 7: 879-82. PMID 26492007 DOI: 10.1038/Nchem.2336  0.34
2015 Cheng B, Trauner D. A Highly Convergent and Biomimetic Total Synthesis of Portentol. Journal of the American Chemical Society. 137: 13800-3. PMID 26471956 DOI: 10.1021/Jacs.5B10009  0.351
2015 Laprell L, Repak E, Franckevicius V, Hartrampf F, Terhag J, Hollmann M, Sumser M, Rebola N, DiGregorio DA, Trauner D. Optical control of NMDA receptors with a diffusible photoswitch. Nature Communications. 6: 8076. PMID 26311290 DOI: 10.1038/Ncomms9076  0.772
2015 Hog DT, Huber FM, Jiménez-Osés G, Mayer P, Houk KN, Trauner D. Evolution of a Unified Strategy for Complex Sesterterpenoids: Progress toward Astellatol and the Total Synthesis of (-)-Nitidasin. Chemistry (Weinheim An Der Bergstrasse, Germany). 21: 13646-65. PMID 26300211 DOI: 10.1002/Chem.201501423  0.387
2015 Kimbrough TJ, Roethle PA, Mayer P, Trauner D. Corrigendum: Total Synthesis of Coralloidolides A, B, C, and E. Angewandte Chemie (International Ed. in English). 54: 9743. PMID 26257257 DOI: 10.1002/Anie.201502149  0.785
2015 Bruun S, Stoeppler D, Keidel A, Kuhlmann U, Luck M, Diehl A, Geiger MA, Woodmansee D, Trauner D, Hegemann P, Oschkinat H, Hildebrandt P, Stehfest K. Light-Dark Adaptation of Channelrhodopsin Involves Photoconversion between the all-trans and 13-cis Retinal Isomers. Biochemistry. 54: 5389-400. PMID 26237332 DOI: 10.1021/Acs.Biochem.5B00597  0.306
2015 Borowiak M, Nahaboo W, Reynders M, Nekolla K, Jalinot P, Hasserodt J, Rehberg M, Delattre M, Zahler S, Vollmar A, Trauner D, Thorn-Seshold O. Photoswitchable Inhibitors of Microtubule Dynamics Optically Control Mitosis and Cell Death. Cell. 162: 403-11. PMID 26165941 DOI: 10.1016/J.Cell.2015.06.049  0.646
2015 Broichhagen J, Frank JA, Trauner D. A Roadmap to Success in Photopharmacology. Accounts of Chemical Research. 48: 1947-60. PMID 26103428 DOI: 10.1021/Acs.Accounts.5B00129  0.604
2015 Frank JA, Moroni M, Moshourab R, Sumser M, Lewin GR, Trauner D. Photoswitchable fatty acids enable optical control of TRPV1. Nature Communications. 6: 7118. PMID 25997690 DOI: 10.1038/Ncomms8118  0.611
2015 Strych S, Journot G, Pemberton RP, Wang SC, Tantillo DJ, Trauner D. Biomimetic total synthesis of santalin Y. Angewandte Chemie (International Ed. in English). 54: 5079-83. PMID 25858797 DOI: 10.1002/Anie.201411350  0.374
2015 Damijonaitis A, Broichhagen J, Urushima T, Hüll K, Nagpal J, Laprell L, Schönberger M, Woodmansee DH, Rafiq A, Sumser MP, Kummer W, Gottschalk A, Trauner D. AzoCholine Enables Optical Control of Alpha 7 Nicotinic Acetylcholine Receptors in Neural Networks. Acs Chemical Neuroscience. 6: 701-7. PMID 25741856 DOI: 10.1021/Acschemneuro.5B00030  0.77
2015 AzimiHashemi N, Erbguth K, Vogt A, Riemensperger T, Rauch E, Woodmansee D, Nagpal J, Brauner M, Sheves M, Fiala A, Kattner L, Trauner D, Hegemann P, Gottschalk A, Liewald JF. Erratum: Synthetic retinal analogs modify the spectral and kinetic characteristics of microbial rhodopsin optogenetic tools. Nature Communications. 6: 6458. PMID 25711720 DOI: 10.1038/Ncomms7458  0.566
2015 Berlin S, Szobota S, Reiner A, Carroll EC, Kienzler MA, Guyon A, Xiao T, Trauner D, Isacoff EY. Author response: A family of photoswitchable NMDA receptors Elife. DOI: 10.7554/Elife.12040.024  0.7
2015 Ellerbrock P, Armanino N, Trauner D. Total Synthesis of Epicoccine and Its Dimerization to Dibefurin Synfacts. 11: 114-114. DOI: 10.1055/S-0034-1379810  0.363
2015 Strych S, Journot G, Pemberton RP, Wang SC, Tantillo DJ, Trauner D. Cover Picture: Biomimetic Total Synthesis of Santalin Y (Angew. Chem. Int. Ed. 17/2015) Angewandte Chemie International Edition. 54: 4971-4971. DOI: 10.1002/Anie.201502755  0.328
2015 Kimbrough TJ, Roethle PA, Mayer P, Trauner D. Corrigendum: Total Synthesis of Coralloidolides A, B, C, and E Angewandte Chemie - International Edition. DOI: 10.1002/anie.201502149  0.785
2015 Kimbrough T, Roethle P, Mayer P, Trauner D. Berichtigung: Totalsynthese von Coralloidolid A, B, C und E Angewandte Chemie. 127: 9879-9879. DOI: 10.1002/Ange.201502149  0.765
2014 AzimiHashemi N, Erbguth K, Vogt A, Riemensperger T, Rauch E, Woodmansee D, Nagpal J, Brauner M, Sheves M, Fiala A, Kattner L, Trauner D, Hegemann P, Gottschalk A, Liewald JF. Synthetic retinal analogues modify the spectral and kinetic characteristics of microbial rhodopsin optogenetic tools. Nature Communications. 5: 5810. PMID 25503804 DOI: 10.1038/Ncomms6810  0.588
2014 Stichnoth D, Kölle P, Kimbrough TJ, Riedle E, de Vivie-Riedle R, Trauner D. Photochemical formation of intricarene. Nature Communications. 5: 5597. PMID 25470600 DOI: 10.1038/Ncomms6597  0.782
2014 Ellerbrock P, Armanino N, Trauner D. Biomimetic synthesis of the calcineurin phosphatase inhibitor dibefurin. Angewandte Chemie (International Ed. in English). 53: 13414-8. PMID 25369982 DOI: 10.1002/Anie.201407088  0.377
2014 Broichhagen J, Schönberger M, Cork SC, Frank JA, Marchetti P, Bugliani M, Shapiro AM, Trapp S, Rutter GA, Hodson DJ, Trauner D. Optical control of insulin release using a photoswitchable sulfonylurea. Nature Communications. 5: 5116. PMID 25311795 DOI: 10.1038/Ncomms6116  0.572
2014 Rullo A, Reiner A, Reiter A, Trauner D, Isacoff EY, Woolley GA. Long wavelength optical control of glutamate receptor ion channels using a tetra-ortho-substituted azobenzene derivative. Chemical Communications (Cambridge, England). 50: 14613-5. PMID 25311049 DOI: 10.1039/C4Cc06612J  0.344
2014 Myers E, Herrero-Gómez E, Albrecht I, Lachs J, Mayer P, Hanni M, Ochsenfeld C, Trauner D. Total synthesis of the proposed structure of trichodermatide A. The Journal of Organic Chemistry. 79: 9812-7. PMID 25166497 DOI: 10.1021/Jo501206K  0.318
2014 Broichhagen J, Trauner D. The in vivo chemistry of photoswitched tethered ligands. Current Opinion in Chemical Biology. 21: 121-7. PMID 25108802 DOI: 10.1016/J.Cbpa.2014.07.008  0.313
2014 Schönberger M, Althaus M, Fronius M, Clauss W, Trauner D. Controlling epithelial sodium channels with light using photoswitchable amilorides. Nature Chemistry. 6: 712-9. PMID 25054942 DOI: 10.1038/Nchem.2004  0.305
2014 Hog DT, Huber FM, Mayer P, Trauner D. The total synthesis of (-)-nitidasin. Angewandte Chemie (International Ed. in English). 53: 8513-7. PMID 24962933 DOI: 10.1002/Anie.201403605  0.34
2014 Guimond N, Mayer P, Trauner D. Development of an iron(II)-catalyzed aerobic catechol cleavage and biomimetic synthesis of betanidin. Chemistry (Weinheim An Der Bergstrasse, Germany). 20: 9519-23. PMID 24957632 DOI: 10.1002/Chem.201403436  0.324
2014 Broichhagen J, Jurastow I, Iwan K, Kummer W, Trauner D. Optical control of acetylcholinesterase with a tacrine switch. Angewandte Chemie (International Ed. in English). 53: 7657-60. PMID 24895330 DOI: 10.1002/Anie.201403666  0.318
2014 Meier R, Strych S, Trauner D. Biomimetic synthesis of (±)-merochlorin B. Organic Letters. 16: 2634-7. PMID 24804897 DOI: 10.1021/Ol500800Z  0.357
2014 Tochitsky I, Polosukhina A, Degtyar VE, Gallerani N, Smith CM, Friedman A, Van Gelder RN, Trauner D, Kaufer D, Kramer RH. Restoring visual function to blind mice with a photoswitch that exploits electrophysiological remodeling of retinal ganglion cells. Neuron. 81: 800-13. PMID 24559673 DOI: 10.1016/J.Neuron.2014.01.003  0.504
2014 Chen IT, Baitinger I, Schreyer L, Trauner D. Total synthesis of sandresolide B and amphilectolide. Organic Letters. 16: 166-9. PMID 24308854 DOI: 10.1021/Ol403156R  0.395
2014 Olbrich M, Mayer P, Trauner D. A step toward polytwistane: synthesis and characterization of C2-symmetric tritwistane. Organic & Biomolecular Chemistry. 12: 108-12. PMID 24217004 DOI: 10.1039/C3Ob42152J  0.308
2014 Pangerl M, Höhlein I, Trauner D. A robust route towards functionalized pyrrolizidines as precursors for daphniphyllum alkaloids Synlett. 25: 741-745. DOI: 10.1055/S-0033-1340677  0.343
2014 Hager A, Kuttruff CA, Herrero-Gómez E, Trauner D. Toward the total synthesis of ansalactam A Tetrahedron Letters. 55: 59-62. DOI: 10.1016/J.Tetlet.2013.10.104  0.363
2014 Borowiak M, Nahaboo W, Reynders M, Nekolla K, Jalinot P, Hasserodt J, Rehberg M, Delattre M, Zahler S, Vollmar A, Trauner D, Thorn-Seshold O. Photoswitchable Inhibitors of Microtubule Dynamics Optically Control Mitosis and Cell Death Cell. DOI: 10.1016/j.cell.2015.06.049  0.593
2013 Kienzler MA, Reiner A, Trautman E, Yoo S, Trauner D, Isacoff EY. A red-shifted, fast-relaxing azobenzene photoswitch for visible light control of an ionotropic glutamate receptor. Journal of the American Chemical Society. 135: 17683-6. PMID 24171511 DOI: 10.1021/Ja408104W  0.744
2013 Hager D, Paulitz C, Tiebes J, Mayer P, Trauner D. Total synthesis of herbicidin C and aureonuclemycin: impasses and new avenues. The Journal of Organic Chemistry. 78: 10784-801. PMID 24074399 DOI: 10.1021/Jo401706R  0.365
2013 Löbermann F, Weisheit L, Trauner D. Intramolecular vinyl quinone Diels-Alder reactions: asymmetric entry to the cordiachrome core and synthesis of (-)-isoglaziovianol. Organic Letters. 15: 4324-6. PMID 23962323 DOI: 10.1021/Ol401787N  0.357
2013 Strych S, Trauner D. Biomimetic synthesis of santalin A,B and santarubin A,B, the major colorants of red sandalwood. Angewandte Chemie (International Ed. in English). 52: 9509-12. PMID 23754579 DOI: 10.1002/Anie.201302317  0.318
2013 Webster R, Gaspar B, Mayer P, Trauner D. Studies toward the biomimetic total synthesis of (-)-PF-1018. Organic Letters. 15: 1866-9. PMID 23547904 DOI: 10.1021/Ol400508S  0.322
2013 Banghart MR, Trauner D. A 1H NMR assay for measuring the photostationary States of photoswitchable ligands. Methods in Molecular Biology (Clifton, N.J.). 995: 107-20. PMID 23494375 DOI: 10.1007/978-1-62703-345-9_8  0.695
2013 Kienzler MA, Reiner A, Trauner D, Isacoff E. Synthesis and Characterization of a Red-Shifted, Fast Relaxing, Photoswitchable Tethered Ligand for use in Modified Glutamate Receptors Biophysical Journal. 104: 678a. DOI: 10.1016/J.Bpj.2012.11.3744  0.741
2013 Fehrentz T, Kuttruff CA, Huber FME, Kienzler MA, Mayer P, Trauner D. Corrigendum: Exploring the Pharmacology and Action Spectra of Photochromic Open-Channel Blockers Chembiochem. 14: 1157-1157. DOI: 10.1002/Cbic.201300343  0.723
2012 Trauner D. Molecular switches and cages. Beilstein Journal of Organic Chemistry. 8: 870-1. PMID 23015835 DOI: 10.3762/Bjoc.8.97  0.302
2012 Polosukhina A, Litt J, Tochitsky I, Nemargut J, Sychev Y, De Kouchkovsky I, Huang T, Borges K, Trauner D, Van Gelder RN, Kramer RH. Photochemical restoration of visual responses in blind mice. Neuron. 75: 271-82. PMID 22841312 DOI: 10.1016/J.Neuron.2012.05.022  0.507
2012 Fehrentz T, Kuttruff CA, Huber FM, Kienzler MA, Mayer P, Trauner D. Exploring the pharmacology and action spectra of photochromic open-channel blockers. Chembiochem : a European Journal of Chemical Biology. 13: 1746-9. PMID 22807111 DOI: 10.1002/Cbic.201200216  0.721
2012 Hog DT, Webster R, Trauner D. Synthetic approaches toward sesterterpenoids. Natural Product Reports. 29: 752-79. PMID 22652980 DOI: 10.1039/C2Np20005H  0.31
2012 Matveenko M, Liang G, Lauterwasser EM, Zubía E, Trauner D. A total synthesis prompts the structure revision of haouamine B. Journal of the American Chemical Society. 134: 9291-5. PMID 22545759 DOI: 10.1021/Ja301326K  0.793
2012 Sofiyev V, Lumb JP, Volgraf M, Trauner D. Total synthesis of exiguamines A and B inspired by catecholamine chemistry. Chemistry (Weinheim An Der Bergstrasse, Germany). 18: 4999-5005. PMID 22415756 DOI: 10.1002/Chem.201103605  0.806
2012 Mourot A, Fehrentz T, Le Feuvre Y, Smith CM, Herold C, Dalkara D, Nagy F, Trauner D, Kramer RH. Rapid optical control of nociception with an ion-channel photoswitch. Nature Methods. 9: 396-402. PMID 22343342 DOI: 10.1038/Nmeth.1897  0.533
2012 Kuttruff CA, Geiger S, Cakmak M, Mayer P, Trauner D. An approach to aminonaphthoquinone ansamycins using a modified Danishefsky diene. Organic Letters. 14: 1070-3. PMID 22296114 DOI: 10.1021/Ol203437A  0.345
2012 Tochitsky I, Banghart MR, Mourot A, Yao JZ, Gaub B, Kramer RH, Trauner D. Optochemical control of genetically engineered neuronal nicotinic acetylcholine receptors. Nature Chemistry. 4: 105-11. PMID 22270644 DOI: 10.1038/Nchem.1234  0.75
2012 Levitz J, Gaub B, Janovjak H, Stawski P, Trauner D, Isacoff E. Optical Control of Metabotropic Glutamate Receptors for Probing of G Protein Signaling and Receptor Activation Mechanism Biophysical Journal. 102: 517a. DOI: 10.1016/J.Bpj.2011.11.2827  0.323
2012 Kuttruff CA, Mayer P, Trauner D. Evolution of a synthetic strategy for the variecolortides European Journal of Organic Chemistry. 5151-5161. DOI: 10.1002/Ejoc.201200712  0.337
2011 Mourot A, Kienzler MA, Banghart MR, Fehrentz T, Huber FM, Stein M, Kramer RH, Trauner D. Tuning photochromic ion channel blockers. Acs Chemical Neuroscience. 2: 536-43. PMID 22860175 DOI: 10.1021/Cn200037P  0.79
2011 Cakmak M, Mayer P, Trauner D. An efficient synthesis of loline alkaloids. Nature Chemistry. 3: 543-5. PMID 21697875 DOI: 10.1038/Nchem.1072  0.371
2011 Caporale N, Kolstad KD, Lee T, Tochitsky I, Dalkara D, Trauner D, Kramer R, Dan Y, Isacoff EY, Flannery JG. LiGluR restores visual responses in rodent models of inherited blindness. Molecular Therapy : the Journal of the American Society of Gene Therapy. 19: 1212-9. PMID 21610698 DOI: 10.1038/Mt.2011.103  0.509
2011 Fortin DL, Dunn TW, Fedorchak A, Allen D, Montpetit R, Banghart MR, Trauner D, Adelman JP, Kramer RH. Optogenetic photochemical control of designer K+ channels in mammalian neurons. Journal of Neurophysiology. 106: 488-96. PMID 21525363 DOI: 10.1152/Jn.00251.2011  0.752
2011 Hager A, Mazunin D, Mayer P, Trauner D. Synthetic studies toward A-74528. Organic Letters. 13: 1386-9. PMID 21323383 DOI: 10.1021/Ol103117J  0.307
2011 Kuttruff CA, Zipse H, Trauner D. Concise total syntheses of variecolortides A and B through an unusual hetero-Diels-Alder reaction. Angewandte Chemie (International Ed. in English). 50: 1402-5. PMID 21290522 DOI: 10.1002/Anie.201006154  0.333
2011 Cakmak M, Mayer P, Trauner D. Synthesis of the Loline Alkaloids Synfacts. 2011: 1049-1049. DOI: 10.1055/S-0030-1261140  0.375
2011 Kuttruff CA, Zipse H, Trauner D. Synthesis of Variecolortides A and B Synfacts. 2011: 588-588. DOI: 10.1055/S-0030-1260368  0.346
2011 Levitz J, Gaub B, Janovjak H, Stawski P, Trauner D, Isacoff EY. Design and Application of a Light-Activated Metabotropic Glutamate Receptor for Optical Control of Intracellular Signaling Pathways Biophysical Journal. 100: 177a. DOI: 10.1016/J.Bpj.2010.12.1188  0.341
2011 Volgraf M, Banghart M, Trauner D. Switchable Proteins and Channels Molecular Switches, Second Edition. 1: 563-593. DOI: 10.1002/9783527634408.ch15  0.772
2010 Lumb JP, Krinsky JL, Trauner D. Theoretical investigation of the rubicordifolin cascade. Organic Letters. 12: 5162-5. PMID 20973524 DOI: 10.1021/Ol102157D  0.613
2010 Löbermann F, Mayer P, Trauner D. Biomimetic synthesis of (-)-pycnanthuquinone C through the Diels-Alder reaction of a vinyl quinone. Angewandte Chemie (International Ed. in English). 49: 6199-202. PMID 20645370 DOI: 10.1002/Anie.201001862  0.339
2010 Janovjak H, Szobota S, Wyart C, Trauner D, Isacoff EY. A light-gated, potassium-selective glutamate receptor for the optical inhibition of neuronal firing. Nature Neuroscience. 13: 1027-32. PMID 20581843 DOI: 10.1038/Nn.2589  0.309
2010 Kimbrough TJ, Roethle PA, Mayer P, Trauner D. Total synthesis of coralloidolides A, B, C, and E. Angewandte Chemie (International Ed. in English). 49: 2619-21. PMID 20217876 DOI: 10.1002/Anie.200906126  0.79
2010 Bishop LM, Roberson RE, Bergman RG, Trauner D. On the development of catalytic carba-6π electrocyclizations Synthesis. 2233-2244. DOI: 10.1055/S-0029-1218812  0.446
2010 Pangerl M, Hughes CC, Trauner D. Total synthesis of newbouldine via reductive N-N bond formation Tetrahedron. 66: 6626-6631. DOI: 10.1016/J.Tet.2010.05.085  0.585
2010 Fehrentz T, Mourot A, Kienzler M, Tsunozaki M, Banghart M, Bautista D, Trauner D, Kramer RH. Light Control of Cell Excitability Using a Photochromic Blocker for Voltage-Gated Ion Channels Biophysical Journal. 98: 113a. DOI: 10.1016/J.Bpj.2009.12.4207  0.791
2010 Mourot A, Fehrentz T, Kienzler M, Tochitsky I, Banghart MR, Trauner D, Kramer RH. Photopharmacology: Controlling Native Voltage-Gated Ion Channels with Light Biophysical Journal. 98: 212a. DOI: 10.1016/J.Bpj.2009.12.1143  0.787
2010 Chemler SR, Trauner D, Danishefsky SJ. ChemInform Abstract: The B-Alkyl Suzuki-Miyaura Cross-Coupling Reaction: Development, Mechanistic Study, and Applications in Natural Product Synthesis Cheminform. 33: no-no. DOI: 10.1002/CHIN.200216251  0.628
2010 MULZER J, BATS JW, LIST B, OPATZ T, TRAUNER D. ChemInform Abstract: The Phenanthrenone Approach to Opium Alkaloids: Formal Total Synthesis of Morphine by Sigmatropic Rearrangement. Cheminform. 28: no-no. DOI: 10.1002/chin.199742259  0.345
2010 Kimbrough T, Roethle P, Mayer P, Trauner D. Totalsynthese von Coralloidolid A, B, C und E Angewandte Chemie. 122: 2675-2678. DOI: 10.1002/Ange.200906126  0.765
2009 Banghart MR, Mourot A, Fortin DL, Yao JZ, Kramer RH, Trauner D. Photochromic blockers of voltage-gated potassium channels. Angewandte Chemie (International Ed. in English). 48: 9097-101. PMID 19882609 DOI: 10.1002/Anie.200904504  0.757
2009 Kramer RH, Fortin DL, Trauner D. New photochemical tools for controlling neuronal activity. Current Opinion in Neurobiology. 19: 544-52. PMID 19828309 DOI: 10.1016/J.Conb.2009.09.004  0.542
2009 Numano R, Szobota S, Lau AY, Gorostiza P, Volgraf M, Roux B, Trauner D, Isacoff EY. Nanosculpting reversed wavelength sensitivity into a photoswitchable iGluR. Proceedings of the National Academy of Sciences of the United States of America. 106: 6814-9. PMID 19342491 DOI: 10.1016/J.Neures.2010.07.2065  0.731
2009 Bowie AL, Trauner D. Total synthesis of (+/-)-rhazinal using novel palladium-catalyzed cyclizations. The Journal of Organic Chemistry. 74: 1581-6. PMID 19170539 DOI: 10.1021/Jo801791J  0.794
2009 Andersen R, Trauner D, Volgraf M, Lumb J, Brastianos H, Carr G, Chung M, Münzel M, Mauk A. Synthesis of Exiguamine A Synfacts. 2009: 0233-0233. DOI: 10.1055/S-0028-1087689  0.651
2009 Lumb J-, Choong KC, Trauner D. Synthesis of Rubioncolin B Synfacts. 2009: 3-3. DOI: 10.1055/S-0028-1087237  0.346
2009 Mourot A, Banghart MR, Fortin DL, Trauner D, Kramer RH. Light At The End Of The Channel: Photochromic Blockers For Optical Control Of Ion Channels In Individual Cells Biophysical Journal. 96: 179a. DOI: 10.1016/J.Bpj.2008.12.836  0.761
2009 Szobota S, Numano R, Wyart C, Gorostiza P, Volgraf M, Fortin DL, Del Bene F, Scott EK, Kramer RH, Trauner D, Isacoff EY. Engineering light-gated glutamate receptors Biophysical Journal. 96: 489a. DOI: 10.1016/J.Bpj.2008.12.2523  0.759
2009 Banghart MR, Mourot A, Fortin DL, Kramer RH, Trauner D. Discovery Of Photochromic Ligands That Block Voltage-gated K+ Channels At The Internal TEA Binding Site Biophysical Journal. 96: 23a. DOI: 10.1016/J.Bpj.2008.12.1022  0.755
2009 Banghart M, Mourot A, Fortin D, Yao J, Kramer R, Trauner D. Photochrome Liganden für spannungsgesteuerte Kaliumkanäle Angewandte Chemie. 121: 9261-9265. DOI: 10.1002/Ange.200904504  0.724
2008 Bishop LM, Barbarow JE, Bergman RG, Trauner D. Catalysis of 6pi electrocyclizations. Angewandte Chemie (International Ed. in English). 47: 8100-3. PMID 18785197 DOI: 10.1002/Anie.200803336  0.758
2008 Volgraf M, Lumb JP, Brastianos HC, Carr G, Chung MK, Münzel M, Mauk AG, Andersen RJ, Trauner D. Biomimetic synthesis of the IDO inhibitors exiguamine A and B. Nature Chemical Biology. 4: 535-7. PMID 18677305 DOI: 10.1038/Nchembio.107  0.803
2008 Lumb JP, Choong KC, Trauner D. ortho-Quinone methides from para-quinones: total synthesis of rubioncolin B. Journal of the American Chemical Society. 130: 9230-1. PMID 18582058 DOI: 10.1021/Ja803498R  0.662
2008 Kienzler MA, Suseno S, Trauner D. Vinyl quinones as Diels-Alder dienes: concise synthesis of (-)-halenaquinone. Journal of the American Chemical Society. 130: 8604-5. PMID 18549215 DOI: 10.1021/Ja8035042  0.766
2008 Bishop LM, Winkler M, Houk KN, Bergman RG, Trauner D. Mechanistic investigations of the acid-catalyzed cyclization of a vinyl ortho-quinone methide. Chemistry (Weinheim An Der Bergstrasse, Germany). 14: 5405-8. PMID 18449871 DOI: 10.1002/Chem.200800662  0.444
2008 Roethle PA, Trauner D. The chemistry of marine furanocembranoids, pseudopteranes, gersolanes, and related natural products. Natural Product Reports. 25: 298-317. PMID 18389139 DOI: 10.1039/B705660P  0.772
2008 Fortin DL, Banghart MR, Dunn TW, Borges K, Wagenaar DA, Gaudry Q, Karakossian MH, Otis TS, Kristan WB, Trauner D, Kramer RH. Photochemical control of endogenous ion channels and cellular excitability. Nature Methods. 5: 331-8. PMID 18311146 DOI: 10.1038/Nmeth.1187  0.754
2008 Beaulieu ED, Voss L, Trauner D. Conjugate addition of allyl stannanes with concomitant triflation. Organic Letters. 10: 869-72. PMID 18232702 DOI: 10.1021/Ol702996T  0.34
2008 Harvey JH, Trauner D. Regulating enzymatic activity with a photoswitchable affinity label. Chembiochem : a European Journal of Chemical Biology. 9: 191-3. PMID 18085544 DOI: 10.1002/Cbic.200700570  0.622
2008 Sofiyev V, Navarro G, Trauner D. Biomimetic synthesis of the shimalactones. Organic Letters. 10: 149-52. PMID 18072785 DOI: 10.1021/Ol702806V  0.806
2008 Wang S, Wang Y, Szobota S, Volgraf M, Liu Z, Sun C, Trauner D, Isacoff EY, Zhang X. All optical platform for parallel and spatiotemporal control of neuronal activity Optics Infobase Conference Papers. DOI: 10.1364/Fio.2008.Ftul4  0.72
2008 Sofiyev V, Navarro G, Trauner D. Synthesis of Shimalactone A Synfacts. 2008: 451-451. DOI: 10.1055/S-2008-1072710  0.804
2008 Harvey JH, Trauner D. Cover Picture: Regulating Enzymatic Activity with a Photoswitchable Affinity Label (ChemBioChem 2/2008) Chembiochem. 9: 165-165. DOI: 10.1002/Cbic.200890000  0.569
2007 Malerich JP, Maimone TJ, Elliott GI, Trauner D. Biomimetic Synthesis of Antimalarial Naphthoquinones. Journal of the American Chemical Society. 129: 1836. PMID 27518592 DOI: 10.1021/Ja069018L  0.805
2007 Wang S, Szobota S, Wang Y, Volgraf M, Liu Z, Sun C, Trauner D, Isacoff EY, Zhang X. All optical interface for parallel, remote, and spatiotemporal control of neuronal activity. Nano Letters. 7: 3859-63. PMID 18034506 DOI: 10.1021/Nl072783T  0.71
2007 Comstock MJ, Levy N, Kirakosian A, Cho J, Lauterwasser F, Harvey JH, Strubbe DA, Fréchet JM, Trauner D, Louie SG, Crommie MF. Reversible photomechanical switching of individual engineered molecules at a metallic surface. Physical Review Letters. 99: 038301. PMID 17678335 DOI: 10.1103/Physrevlett.99.038301  0.59
2007 Roethle PA, Chen IT, Trauner D. Total synthesis of (-)-archazolid B. Journal of the American Chemical Society. 129: 8960-1. PMID 17595091 DOI: 10.1021/Ja0733033  0.808
2007 Gorostiza P, Volgraf M, Numano R, Szobota S, Trauner D, Isacoff EY. Mechanisms of photoswitch conjugation and light activation of an ionotropic glutamate receptor. Proceedings of the National Academy of Sciences of the United States of America. 104: 10865-70. PMID 17578923 DOI: 10.1073/Pnas.0701274104  0.731
2007 Szobota S, Gorostiza P, Del Bene F, Wyart C, Fortin DL, Kolstad KD, Tulyathan O, Volgraf M, Numano R, Aaron HL, Scott EK, Kramer RH, Flannery J, Baier H, Trauner D, et al. Remote control of neuronal activity with a light-gated glutamate receptor. Neuron. 54: 535-45. PMID 17521567 DOI: 10.1016/J.Neuron.2007.05.010  0.76
2007 Wilson EM, Trauner D. Concise synthesis of the bacterial DNA primase inhibitor (+) -Sch 642305. Organic Letters. 9: 1327-9. PMID 17338537 DOI: 10.1021/Ol070173U  0.347
2007 Volgraf M, Gorostiza P, Szobota S, Helix MR, Isacoff EY, Trauner D. Reversibly caged glutamate: a photochromic agonist of ionotropic glutamate receptors. Journal of the American Chemical Society. 129: 260-1. PMID 17212390 DOI: 10.1021/Ja067269O  0.716
2007 Comstock MJ, Levy N, Kirakosian A, Cho J, Lauterwasser F, Harvey JH, Strubbe DA, Fréchet JMJ, Trauner D, Louie SG, Crommie MF. Reversible photomechanical switching of individual engineered molecules at a metallic surface Physical Review Letters. 99. DOI: 10.1103/PhysRevLett.99.038301  0.513
2007 Trauner D, Roethle P, Hernandez P. Synthesis of (-)-Bipinnatin J and (+)-Intricarene Synfacts. 2007: 0460-0460. DOI: 10.1055/S-2007-968394  0.354
2007 Trauner D, Miller A, Hughes C, Kennedy-Smith J, Gradl S. Synthesis of (-)-Heptemerone B Synfacts. 2007: 0455-0455. DOI: 10.1055/S-2007-968393  0.797
2007 Trauner D, Liang G, Xu Y, Seiple I. Synthesis of Taiwaniaquinoids Synfacts. 2007: 0126-0126. DOI: 10.1055/S-2006-955768  0.701
2007 Harvey JH, Butler BK, Trauner D. Functionalized azobenzenes through cross-coupling with organotrifluoroborates Tetrahedron Letters. 48: 1661-1664. DOI: 10.1016/J.Tetlet.2006.12.043  0.617
2007 Rosa CP, Kienzler MA, Olson BS, Liang G, Trauner D. Total synthesis of smenochromene B through ring contraction Tetrahedron. 63: 6529-6534. DOI: 10.1016/J.Tet.2007.03.069  0.792
2007 Miller AK, Hughes CC, Kennedy-Smith JJ, Gradl SN, Trauner D. Total Synthesis of (-)-Heptemerone B (I) and (-)-Guanacastepene E (II). Cheminform. 38. DOI: 10.1002/chin.200719168  0.521
2007 Gradl SN, Trauner D. The Meerwein-Eschenmoser-Claisen Rearrangement The Claisen Rearrangement: Methods and Applications. 367-396. DOI: 10.1002/9783527610549.ch7  0.678
2006 Miller AK, Hughes CC, Kennedy-Smith JJ, Gradl SN, Trauner D. Total synthesis of (-)-heptemerone B and (-)-guanacastepene E. Journal of the American Chemical Society. 128: 17057-62. PMID 17177458 DOI: 10.1021/Ja0660507  0.809
2006 Banghart MR, Volgraf M, Trauner D. Engineering light-gated ion channels. Biochemistry. 45: 15129-41. PMID 17176035 DOI: 10.1021/Bi0618058  0.788
2006 Roethle PA, Hernandez PT, Trauner D. Exploring biosynthetic relationships among furanocembranoids: synthesis of (-)-bipinnatin J, (+)-intricarene, (+)-rubifolide, and (+)-isoepilophodione B. Organic Letters. 8: 5901-4. PMID 17134301 DOI: 10.1021/Ol062581O  0.808
2006 Müller M, Kusebauch B, Liang G, Beaudry CM, Trauner D, Hertweck C. Photochemical origin of the immunosuppressive SNF4435C/D and formation of orinocin through "polyene splicing". Angewandte Chemie (International Ed. in English). 45: 7835-8. PMID 17066387 DOI: 10.1002/Anie.200602840  0.689
2006 Liang G, Xu Y, Seiple IB, Trauner D. Synthesis of taiwaniaquinoids via Nazarov triflation. Journal of the American Chemical Society. 128: 11022-3. PMID 16925409 DOI: 10.1021/Ja062505G  0.765
2006 Chambers JJ, Banghart MR, Trauner D, Kramer RH. Light-induced depolarization of neurons using a modified Shaker K(+) channel and a molecular photoswitch. Journal of Neurophysiology. 96: 2792-6. PMID 16870840 DOI: 10.1152/Jn.00318.2006  0.786
2006 Roethle PA, Trauner D. Expedient synthesis of (+/-)-bipinnatin J. Organic Letters. 8: 345-7. PMID 16408911 DOI: 10.1021/Ol052922I  0.806
2006 Volgraf M, Gorostiza P, Numano R, Kramer RH, Isacoff EY, Trauner D. Allosteric control of an ionotropic glutamate receptor with an optical switch. Nature Chemical Biology. 2: 47-52. PMID 16408092 DOI: 10.1038/Nchembio756  0.769
2006 Grundl MA, Trauner D. Synthetic studies toward the haouamines. Organic Letters. 8: 23-5. PMID 16381558 DOI: 10.1021/Ol052262H  0.35
2006 Miller AK, Trauner D. Mapping the chemistry of highly unsaturated pyrone polyketides Synlett. 2295-2316. DOI: 10.1055/S-2006-949627  0.582
2006 Bowie AJ, Hughes CC, Trauner D. Synthesis of (±)-Rhazinilam Synfacts. 2006: 310-310. DOI: 10.1055/S-2006-932035  0.524
2006 Beaudry CM, Trauner D. Total Synthesis of (-)-SNF4435 C (I) and (+)-SNF4435 D (II). Cheminform. 37. DOI: 10.1002/chin.200607222  0.629
2006 Müller M, Kusebauch B, Liang G, Beaudry CM, Trauner D, Hertweck C. Photochemische Herkunft der Immunsuppressiva SNF4435C/D und Bildung von Orinocin durch “Polyen-Splicing” Angewandte Chemie. 118: 7999-8002. DOI: 10.1002/Ange.200602840  0.678
2005 Endicott CA, Strauss HL, Hughes CC, Trauner D. Infrared hole burning and conformational change in a borane-ammonia complex. The Journal of Physical Chemistry. A. 109: 7714-7. PMID 16834146 DOI: 10.1021/Jp051969I  0.502
2005 Kramer RH, Chambers JJ, Trauner D. Photochemical tools for remote control of ion channels in excitable cells. Nature Chemical Biology. 1: 360-5. PMID 16370371 DOI: 10.1038/Nchembio750  0.69
2005 Lumb JP, Trauner D. Pericyclic reactions of prenylated naphthoquinones: biomimetic syntheses of mollugin and microphyllaquinone. Organic Letters. 7: 5865-8. PMID 16354086 DOI: 10.1021/Ol052472U  0.643
2005 Beaudry CM, Malerich JP, Trauner D. Biosynthetic and biomimetic electrocyclizations. Chemical Reviews. 105: 4757-78. PMID 16351061 DOI: 10.1021/Cr0406110  0.787
2005 Bowie AL, Hughes CC, Trauner D. Concise synthesis of (+/-)-rhazinilam through direct coupling. Organic Letters. 7: 5207-9. PMID 16268539 DOI: 10.1021/Ol052033V  0.796
2005 Zuidema DR, Miller AK, Trauner D, Jones PB. Photosensitized conversion of 9,10-deoxytridachione to photodeoxytridachione. Organic Letters. 7: 4959-62. PMID 16235932 DOI: 10.1021/Ol051887C  0.559
2005 Beaudry CM, Trauner D. Total synthesis of (-)-SNF4435 C and (+)-SNF4435 D. Organic Letters. 7: 4475-7. PMID 16178562 DOI: 10.1021/Ol051790Q  0.692
2005 Hughes CC, Miller AK, Trauner D. An electrochemical approach to the guanacastepenes. Organic Letters. 7: 3425-8. PMID 16048308 DOI: 10.1021/Ol047387L  0.664
2005 Barbarow JE, Miller AK, Trauner D. Biomimetic synthesis of elysiapyrones A and B. Organic Letters. 7: 2901-3. PMID 15987165 DOI: 10.1055/S-2005-921593  0.804
2005 Liang G, Seiple IB, Trauner D. Stereoselective syntheses of the bioactive polypropionates aureothin, N-acetylaureothamine, and aureonitrile. Organic Letters. 7: 2837-9. PMID 15987149 DOI: 10.1021/Ol050703R  0.718
2005 Miller AK, Trauner D. Mining the tetraene manifold: total synthesis of complex pyrones from Placobranchus ocellatus. Angewandte Chemie (International Ed. in English). 44: 4602-6. PMID 15981289 DOI: 10.1002/Anie.200500488  0.564
2005 Malerich JP, Maimone TJ, Elliott GI, Trauner D. Biomimetic synthesis of antimalarial naphthoquinones. Journal of the American Chemical Society. 127: 6276-83. PMID 15853334 DOI: 10.1021/Ja050092Y  0.804
2005 Khuong KS, Beaudry CM, Trauner D, Houk KN. Dienophile twisting and substituent effects influence reaction rates of intramolecular Diels-Alder cycloadditions: a DFT study. Journal of the American Chemical Society. 127: 3688-9. PMID 15771490 DOI: 10.1021/Ja050135A  0.66
2005 Lumb JP, Trauner D. Biomimetic synthesis and structure elucidation of rubicordifolin, a cytotoxic natural product from Rubia cordifolia. Journal of the American Chemical Society. 127: 2870-1. PMID 15740120 DOI: 10.1021/Ja042375G  0.624
2005 Liang G, Miller AK, Trauner D. Stereoselective synthesis of cyercene A and the placidenes. Organic Letters. 7: 819-21. PMID 15727449 DOI: 10.1021/Ol047542W  0.666
2005 Hughes CC, Miller AK, Trauner D. Electrochemical Synthesis of Oxygenated Dihydrofurans Synfacts. 2005: 298-298. DOI: 10.1055/S-2005-916144  0.536
2005 Olson BS, Trauner D. Concise synthesis of (±)-smenochromene D (= likonide B) Synlett. 700-702. DOI: 10.1055/S-2005-863713  0.327
2005 Hughes CC, Trauner D. Palladium-Catalyzed Couplings to Nucleophilic Heteroarenes: The Total Synthesis of (-)-Frondosin B. Cheminform. 36. DOI: 10.1016/J.Tet.2004.07.041  0.609
2005 Malerich JP, Trauner D. Biomimetic Synthesis of Natural Products Isolated from Bignoniaceae Cheminform. 36. DOI: 10.1002/chin.200546257  0.707
2005 Barbarow JE, Miller AK, Trauner D. Biomimetic Synthesis of Elysiapyrones A (I) and B (II). Cheminform. 36. DOI: 10.1002/chin.200546203  0.783
2004 Banghart M, Borges K, Isacoff E, Trauner D, Kramer RH. Light-activated ion channels for remote control of neuronal firing. Nature Neuroscience. 7: 1381-6. PMID 15558062 DOI: 10.1038/Nn1356  0.759
2004 Liang G, Trauner D. Enantioselective Nazarov reactions through catalytic asymmetric proton transfer. Journal of the American Chemical Society. 126: 9544-5. PMID 15291550 DOI: 10.1021/Ja0476664  0.504
2004 Miller AK, Byun DH, Beaudry CM, Trauner D. The total synthesis of (-)-crispatene. Proceedings of the National Academy of Sciences of the United States of America. 101: 12019-23. PMID 15273284 DOI: 10.1073/Pnas.0401787101  0.771
2004 Trauner D, Kramer RH. Metabolic modulation of potassium channels. Science's Stke : Signal Transduction Knowledge Environment. 2004: pe22. PMID 15150422 DOI: 10.1126/Stke.2332004Pe22  0.527
2004 Malerich JP, Trauner D. Chapter 13 Biomimetic synthesis of natural products isolated from Bignoniaceae Strategies and Tactics in Organic Synthesis. 5: 417-436. DOI: 10.1016/S1874-6004(04)80036-4  0.73
2004 Hughes CC, Trauner D. Palladium-catalyzed couplings to nucleophilic heteroarenes: The total synthesis of (-)-frondosin B Tetrahedron. 60: 9675-9686. DOI: 10.1016/j.tet.2004.07.041  0.554
2004 Miller AK, Banghart MR, Beaudry CM, Suh JM, Trauner D. Development of Novel Lewis Acid Catalyzed Cycloisomerizations: Synthesis of Bicyclo[3.1.0]hexenes and Cyclopentenones. Cheminform. 35. DOI: 10.1016/J.Tet.2003.04.006  0.8
2003 Liang G, Gradl SN, Trauner D. Efficient Nazarov cyclizations of 2-alkoxy-1,4-pentadien-3-ones. Organic Letters. 5: 4931-4. PMID 14682732 DOI: 10.1021/Ol036019Z  0.767
2003 Hughes CC, Kennedy-Smith JJ, Trauner D. Synthetic studies toward the guanacastepenes. Organic Letters. 5: 4113-5. PMID 14572262 DOI: 10.1021/Ol035559T  0.572
2003 Gradl SN, Felix JP, Isacoff EY, Garcia ML, Trauner D. Protein surface recognition by rational design: nanomolar ligands for potassium channels. Journal of the American Chemical Society. 125: 12668-9. PMID 14558789 DOI: 10.1021/Ja036155Z  0.701
2003 Dorsey AD, Barbarow JE, Trauner D. Reductive cyclization of delta-hydroxy nitriles: a new synthesis of glycosylamines. Organic Letters. 5: 3237-9. PMID 12943396 DOI: 10.1021/Ol035111S  0.797
2003 Malerich JP, Trauner D. Biomimetic synthesis of (+/-)-pinnatal and (+/-)-sterekunthal A. Journal of the American Chemical Society. 125: 9554-5. PMID 12903998 DOI: 10.1021/Ja036026I  0.749
2003 Ng SM, Beaudry CM, Trauner D. Intramolecular Diels-Alder reactions of 5-vinyl-1,3-cyclohexadienes. Organic Letters. 5: 1701-4. PMID 12735756 DOI: 10.1021/Ol0343414  0.664
2003 Miller AK, Trauner D. Total synthesis of (+/-)-photodeoxytridachione through a Lewis acid catalyzed cyclization. Angewandte Chemie (International Ed. in English). 42: 549-52. PMID 12569487 DOI: 10.1002/Anie.200390158  0.587
2003 Miller AK, Banghart MR, Beaudry CM, Suh JM, Trauner D. Development of novel Lewis acid catalyzed cycloisomerizations: Synthesis of bicyclo[3.1.0]hexenes and cyclopentenones Tetrahedron. 59: 8919-8930. DOI: 10.1016/j.tet.2003.04.006  0.792
2003 Malerich JP, Trauner D. Biomimetic Synthesis of (.+-.)-Pinnatal and (.+-.)-Sterekunthal A. Cheminform. 34. DOI: 10.1002/chin.200348210  0.734
2002 Hughes CC, Trauner D. Concise total synthesis of (-)-frondosin B using a novel palladium-catalyzed cyclization. Angewandte Chemie (International Ed. in English). 41: 1569-72. PMID 19750668 DOI: 10.1002/1521-3773(20020503)41:9<1569::Aid-Anie1569>3.0.Co;2-8  0.614
2002 Hughes CC, Trauner D. The total synthesis of (-)-amathaspiramide F. Angewandte Chemie (International Ed. in English). 41: 4556-9. PMID 12458537 DOI: 10.1002/1521-3773(20021202)41:23<4556::Aid-Anie4556>3.0.Co;2-E  0.533
2002 Hughes CC, Scharn D, Mulzer J, Trauner D. Borane-ammonia complexes stabilized by hydrogen bonding. Organic Letters. 4: 4109-11. PMID 12423098 DOI: 10.1021/Ol026865U  0.632
2002 Beaudry CM, Trauner D. Synthetic studies toward SNF4435 C and SNF4435 D. Organic Letters. 4: 2221-4. PMID 12074672 DOI: 10.1021/Ol026069O  0.665
2002 Gradl SN, Kennedy-Smith JJ, Kim J, Trauner D. A Practical Variant of the Claisen-Eschenmoser Rearrangement: Synthesis of Unsaturated Morpholine Amides Synlett. 2002: 0411-0414. DOI: 10.1055/S-2002-20453  0.727
2002 Hughes CC, Trauner D. Concise Total Synthesis of (−)-Frondosin B Using a Novel Palladium-Catalyzed Cyclization This work was supported by a generous gift from Merck & Co. Angewandte Chemie International Edition. 41: 2227. DOI: 10.1002/1521-3773(20020703)41:13<2227::Aid-Anie11112227>3.0.Co;2-S  0.587
2002 Gradl SN, Kennedy-Smith JJ, Kim J, Trauner D. A practical variant of the Claisen-Eschenmoser rearrangement: Synthesis of unsaturated morpholine amides Synlett. 411-414.  0.7
2001 Carson MW, Kim G, Hentemann MF, Trauner D, Danishefsky SJ. Concise Stereoselective Routes to Advanced Intermediates Related to Natural and Unnatural Pinnaic Acid This work was supported by the National Institutes of Health (Grant Numbers: CA28824). Postdoctoral Fellowship support is gratefully acknowledged by M.W.C. (U.S. Army BCRP, DAMD17-98-1-8154), M.F.H. (5T32 CA62948-05), and D.T. (Schering Research Foundation, Berlin). We thank Dr. George Sukenick of the MSKCC NMR Core Facility for NMR and mass spectral analyses. Angewandte Chemie (International Ed. in English). 40: 4450-4452. PMID 12404442 DOI: 10.1002/1521-3773(20011203)40:23<4450::AID-ANIE4450>3.0.CO;2-M  0.321
2001 Chemler SR, Trauner D, Danishefsky SJ. The B-Alkyl Suzuki-Miyaura Cross-Coupling Reaction: Development, Mechanistic Study, and Applications in Natural Product Synthesis A list of abbreviations can be found at the end of the article. Angewandte Chemie (International Ed. in English). 40: 4544-4568. PMID 12404358 DOI: 10.1002/1521-3773(20011217)40:24<4544::Aid-Anie4544>3.0.Co;2-N  0.7
2001 Chemler SR, Trauner D, Danishefsky SJ. DieB-Alkyl-Suzuki-Miyaura-Kreuzkupplung: Entwicklung, Untersuchungen zum Mechanismus und Anwendungen in der Naturstoffsynthese Angewandte Chemie. 113: 4676-4701. DOI: 10.1002/1521-3757(20011217)113:24<4676::Aid-Ange4676>3.0.Co;2-B  0.659
2000 Danishefsky SJ, Inoue M, Trauner D. Synthesis of immunomodulatory marine natural products. Ernst Schering Research Foundation Workshop. 1-24. PMID 11077604 DOI: 10.1007/978-3-662-04042-3_1  0.408
2000 Novak BH, Hudlicky T, Reed JW, Mulzer J, Trauner D. Morphine synthesis and biosynthesis - An update Current Organic Chemistry. 4: 343-362. DOI: 10.2174/1385272003376292  0.503
2000 Trauner D, Churchill D, Danishefsky S. On the Conformations of Halichlorine and the Pinnaic Acids: Nitrogen Inversion as a Possible Determinant of Biological Profile Helvetica Chimica Acta. 83: 2344-2351. DOI: 10.1002/1522-2675(20000906)83:9<2344::Aid-Hlca2344>3.0.Co;2-2  0.455
1999 Trauner D, Schwarz JB, Danishefsky SJ. Total Synthesis of (+)-Halichlorine: An Inhibitor of VCAM-1 Expression. Angewandte Chemie (International Ed. in English). 38: 3542-3545. PMID 10602236 DOI: 10.1002/(Sici)1521-3773(19991203)38:23<3542::Aid-Anie3542>3.0.Co;2-I  0.494
1999 Trauner D, Danishefsky SJ. Studies towards the total synthesis of halichlorine: asymmetric synthesis of the spiroquinolizidine subunit Tetrahedron Letters. 40: 6513-6516. DOI: 10.1016/S0040-4039(99)01170-3  0.541
1999 Porth S, Bats JW, Trauner D, Giester G, Mulzer J. Insight into the Mechanism of the Saegusa Oxidation: Isolation of a Novel Palladium(0)–Tetraolefin Complex Angewandte Chemie. 38: 2015-2016. DOI: 10.1002/(Sici)1521-3773(19990712)38:13/14<2015::Aid-Anie2015>3.0.Co;2-#  0.498
1999 Trauner D, Schwarz J, Danishefsky S. Totalsynthese von (+)-Halichlorin, einem Inhibitor der Expression von VCAM-1 Angewandte Chemie. 111: 3756-3758. DOI: 10.1002/(Sici)1521-3757(19991203)111:23<3756::Aid-Ange3756>3.0.Co;2-9  0.383
1999 Porth S, Bats JW, Trauner D, Giester G, Mulzer J. Einblick in den Mechanismus der Saegusa‐Oxidation: Isolierung eines neuartigen Palladium(0)‐Tetraolefin‐Komplexes Angewandte Chemie. 111: 2159-2161. DOI: 10.1002/(Sici)1521-3757(19990712)111:13/14<2159::Aid-Ange2159>3.0.Co;2-5  0.454
1999 Mulzer J, Trauner D. Practical synthesis of (-)-morphine Chirality. 11: 475-482. DOI: 10.1002/(Sici)1520-636X(1999)11:5/6<475::Aid-Chir20>3.0.Co;2-G  0.559
1998 Trauner D, Bats JW, Werner A, Mulzer J. Synthesis of Enantiomerically Pure Morphine Alkaloids: The Hydrophenanthrene Route. The Journal of Organic Chemistry. 63: 5908-5918. PMID 11672195 DOI: 10.1021/Jo9805394  0.539
1998 Mulzer J, Schein K, Böhm I, Trauner D. About the use of molecular workbenches and platforms in organic synthesis Pure and Applied Chemistry. 70: 1487-1493. DOI: 10.1351/Pac199870081487  0.527
1997 Mulzer J, Bats J, List B, Opatz T, Trauner D. The Phenanthrenone Approach to Opium Alkaloids: Formal Total Synthesis of Morphine by Sigmatropic Rearrangement Synlett. 1997: 441-444. DOI: 10.1055/S-1997-6135  0.585
1996 Mulzer J, Dürner G, Trauner D. Formale Totalsynthese von (−)‐Morphin über konjugierte Cuprataddition Angewandte Chemie. 108: 3046-3048. DOI: 10.1002/Ange.19961082345  0.448
1996 Mulzer J, Trauner D, Bats JW. Stereoselektive Insertion von Ketenen in O, O‐Acetale: Synthese von β‐Alkoxyestern und 1,4‐Dioxepan‐5‐onen Angewandte Chemie. 108: 2093-2095. DOI: 10.1002/Ange.19961081722  0.453
Low-probability matches (unlikely to be authored by this person)
2014 Schoenberger M, Damijonaitis A, Zhang Z, Nagel D, Trauner D. Development of a new photochromic ion channel blocker via azologization of fomocaine. Acs Chemical Neuroscience. 5: 514-8. PMID 24856540 DOI: 10.1021/Cn500070W  0.3
2003 Böhm C, Austin W, Trauner D. Enzymatic desymmetrization of a centrosymmetric diacetate Tetrahedron: Asymmetry. 14: 71-74. DOI: 10.1016/S0957-4166(02)00787-5  0.296
2013 Levitz J, Pantoja C, Gaub B, Janovjak H, Reiner A, Hoagland A, Schoppik D, Kane B, Stawski P, Schier AF, Trauner D, Isacoff EY. Optical control of metabotropic glutamate receptors. Nature Neuroscience. 16: 507-16. PMID 23455609 DOI: 10.1038/Nn.3346  0.296
2010 Hilf RJ, Bertozzi C, Zimmermann I, Reiter A, Trauner D, Dutzler R. Structural basis of open channel block in a prokaryotic pentameric ligand-gated ion channel. Nature Structural & Molecular Biology. 17: 1330-6. PMID 21037567 DOI: 10.1038/Nsmb.1933  0.291
2006 Grundl MA, Kaster A, Beaulieu ED, Trauner D. Development of a Friedel-Crafts triflation. Organic Letters. 8: 5429-32. PMID 17107039 DOI: 10.1021/Ol061980G  0.291
2020 Reynders M, Matsuura BS, Bérouti M, Simoneschi D, Marzio A, Pagano M, Trauner D. PHOTACs enable optical control of protein degradation. Science Advances. 6: eaay5064. PMID 32128406 DOI: 10.1126/Sciadv.Aay5064  0.291
2018 Farrants H, Gutzeit VA, Acosta Ruiz A, Trauner D, Johnsson K, Levitz J, Broichhagen J. SNAP-tagged nanobodies enable reversible optical control of a G protein-coupled receptor via a remotely tethered photoswitchable ligand. Acs Chemical Biology. PMID 30141622 DOI: 10.1021/Acschembio.8B00628  0.291
1998 Trauner D. New Ventures in the Construction of Complex Heterocycles: Synthesis of Morphine and Hasubanan Alkaloids Synthesis. 1998: 653-664. DOI: 10.1055/S-1998-5927  0.29
2019 Donthamsetti PC, Broichhagen J, Vyklicky V, Stanley C, Fu Z, Visel M, Levitz JL, Javitch JA, Trauner D, Isacoff EY. Genetically Targeted Optical Control of an Endogenous G Protein-Coupled Receptor. Journal of the American Chemical Society. PMID 31291105 DOI: 10.1021/Jacs.9B02895  0.29
2012 Hager D, Mayer P, Paulitz C, Tiebes J, Trauner D. Stereoselective total syntheses of herbicidin C and aureonuclemycin through late-stage glycosylation. Angewandte Chemie (International Ed. in English). 51: 6525-8. PMID 22644891 DOI: 10.1002/Anie.201201826  0.29
2020 Morstein J, Trads JB, Hinnah K, Willems S, Barber DM, Trauner M, Merk D, Trauner D. Optical control of the nuclear bile acid receptor FXR with a photohormone. Chemical Science. 11: 429-434. PMID 32190263 DOI: 10.1039/C9Sc02911G  0.289
2019 Trauner D, Reyes JR. Synthesis of Human Interleukin-8 by Native Chemical Ligation Synfacts. 15: 439. DOI: 10.1055/S-0037-1612404  0.288
2015 Olbrich M, Mayer P, Trauner D. Synthetic studies toward polytwistane hydrocarbon nanorods. The Journal of Organic Chemistry. 80: 2042-55. PMID 25511971 DOI: 10.1021/Jo502618G  0.287
2015 Guo Y, Wolter T, Kubař T, Sumser M, Trauner D, Elstner M. Molecular Dynamics Investigation of gluazo, a Photo-Switchable Ligand for the Glutamate Receptor GluK2. Plos One. 10: e0135399. PMID 26308344 DOI: 10.1371/Journal.Pone.0135399  0.285
2009 Martos V, Bell SC, Santos E, Isacoff EY, Trauner D, de Mendoza J. Molecular recognition and self-assembly special feature: Calix[4]arene-based conical-shaped ligands for voltage-dependent potassium channels. Proceedings of the National Academy of Sciences of the United States of America. 106: 10482-6. PMID 19435843 DOI: 10.1073/Pnas.0813396106  0.285
2020 Trauner D, Ruehmann K. Total Synthesis of a Gene Synfacts. 16: 350. DOI: 10.1055/S-0039-1690344  0.285
2010 Baitinger I, Mayer P, Trauner D. Toward the total synthesis of maoecrystal V: establishment of contiguous quaternary stereocenters. Organic Letters. 12: 5656-9. PMID 21087008 DOI: 10.1021/Ol102446U  0.284
2009 Trauner D. Classics in Stereoselective Synthesis . Von Erick M. Carreira und Lisbet Kvaerno. Angewandte Chemie. 121: 6711-6712. DOI: 10.1002/Ange.200902514  0.284
2005 Trauner D. A glimpse at the grail. Nature Chemical Biology. 1: 189-91. PMID 16408031 DOI: 10.1038/Nchembio0905-189  0.284
2014 Poulsen MH, Nørager NG, Sumser M, Trauner D, Strømgaard K. Characterization of Light-Controllable Polyamine Toxin Inhibitors of Ionotropic Glutamate Receptors Biophysical Journal. 106: 150a-151a. DOI: 10.1016/J.Bpj.2013.11.867  0.283
2020 Trauner D, Morstein J. Clickable UDP-Galactose Analogues Synfacts. 16: 727. DOI: 10.1055/S-0040-1706959  0.283
2019 Morstein J, Awale M, Reymond JL, Trauner D. Mapping the Azolog Space Enables the Optical Control of New Biological Targets. Acs Central Science. 5: 607-618. PMID 31041380 DOI: 10.1021/Acscentsci.8B00881  0.283
2009 Trauner D. Classics in Stereoselective Synthesis. By Erick M. Carreira and Lisbet Kvaerno. Angewandte Chemie International Edition. 48: 6589-6589. DOI: 10.1002/Anie.200902514  0.283
2020 Trauner D, Ruehmann K. How to Repurpose Sanger’s Reagent as a Photocage Synfacts. 16: 599. DOI: 10.1055/S-0040-1707498  0.282
2011 Kerschensteiner L, Löbermann F, Steglich W, Trauner D. Crocipodin, a benzotropolone pigment from the mushroom Leccinum crocipodium (Boletales) Tetrahedron. 67: 1536-1539. DOI: 10.1016/J.Tet.2010.12.060  0.281
2015 Runtsch LS, Barber DM, Mayer P, Groll M, Trauner D, Broichhagen J. Azobenzene-based inhibitors of human carbonic anhydrase II. Beilstein Journal of Organic Chemistry. 11: 1129-35. PMID 26199669 DOI: 10.3762/Bjoc.11.127  0.28
2018 Podewin T, Ast J, Broichhagen J, Fine NHF, Nasteska D, Leippe P, Gailer M, Buenaventura T, Kanda N, Jones BJ, M'Kadmi C, Baneres JL, Marie J, Tomas A, Trauner D, et al. Conditional and Reversible Activation of Class A and B G Protein-Coupled Receptors Using Tethered Pharmacology. Acs Central Science. 4: 166-179. PMID 29532016 DOI: 10.1021/Acscentsci.7B00237  0.28
2020 Trauner D, Fischer C. Efficient Multigram Synthesis of Dibenzoazacyclooctyne for Strain-Promoted Alkyne–Azide Cycloadditions Synfacts. 16: 222. DOI: 10.1055/S-0039-1691637  0.28
2014 Carta V, Pangerl M, Baur R, Puthenkalam R, Ernst M, Trauner D, Sigel E. A pentasymmetric open channel blocker for Cys-loop receptor channels. Plos One. 9: e106688. PMID 25184303 DOI: 10.1371/Journal.Pone.0106688  0.279
2013 Hornig S, Ohmert I, Trauner D, Ader C, Baldus M, Pongs O. Tetraphenylporphyrin derivative specifically blocks members of the voltage-gated potassium channel subfamily Kv1. Channels (Austin, Tex.). 7: 473-82. PMID 24722265 DOI: 10.4161/Chan.25848  0.279
2019 Trauner D, Impastato AC. Design and Synthesis of a Selective CDK7 Covalent Inhibitor Synfacts. 15: 672. DOI: 10.1055/S-0037-1612577  0.279
2017 Schmid M, Trauner D. Inside Back Cover: Biomimetic Synthesis of Complex Flavonoids Isolated from Daemonorops “Dragon's Blood” (Angew. Chem. Int. Ed. 40/2017) Angewandte Chemie. 56: 12373-12373. DOI: 10.1002/Anie.201708380  0.279
2001 Carson MW, Kim G, Hentemann MF, Trauner D, Danishefsky SJ. Concise Stereoselective Routes to Advanced Intermediates Related to Natural and Unnatural Pinnaic Acid Angewandte Chemie. 113: 4582-4584. DOI: 10.1002/1521-3757(20011203)113:23<4582::Aid-Ange4582>3.0.Co;2-G  0.278
2013 Izquierdo-Serra M, Trauner D, Llobet A, Gorostiza P. Optical Modulation of Neurotransmission Biophysical Journal. 104: 497a. DOI: 10.1016/J.Bpj.2012.11.2744  0.278
2013 Reiter A, Skerra A, Trauner D, Schiefner A. A photoswitchable neurotransmitter analogue bound to its receptor. Biochemistry. 52: 8972-4. PMID 24295282 DOI: 10.1021/Bi4014402  0.277
2019 Trauner D, Fischer C. Bioactive Analogues of TAN-2483B Synfacts. 2019: 557. DOI: 10.1055/S-0037-1612503  0.277
2013 Izquierdo-Serra M, Trauner D, Llobet A, Gorostiza P. Optical modulation of neurotransmission using calcium photocurrents through the ion channel LiGluR. Frontiers in Molecular Neuroscience. 6: 3. PMID 23519552 DOI: 10.3389/Fnmol.2013.00003  0.277
2020 Hinnah K, Willems S, Morstein J, Heering J, Hartrampf F, Broichhagen J, Leippe P, Merk D, Trauner D. Photohormones Enable Optical Control of the Peroxisome Proliferator-Activated Receptor Gamma (PPAR). Journal of Medicinal Chemistry. PMID 32886507 DOI: 10.1021/Acs.Jmedchem.0C00654  0.277
2017 Glock P, Broichhagen J, Kretschmer S, Blumhardt P, Mücksch J, Trauner D, Schwille P. Optical control of protein pattern formation. Angewandte Chemie (International Ed. in English). PMID 29266672 DOI: 10.1002/Anie.201712002  0.277
2018 Winter N, Brüggemann A, Haarmann C, George M, Fertig N, Sumser M, Trauner D. Characterization of Photoswitchable Sodium Channel Inhibitors by Planar Patch Clamp Biophysical Journal. 114: 38a. DOI: 10.1016/J.Bpj.2017.11.261  0.276
2013 Stein M, Breit A, Fehrentz T, Gudermann T, Trauner D. Optical control of TRPV1 channels. Angewandte Chemie (International Ed. in English). 52: 9845-8. PMID 23873837 DOI: 10.1002/Anie.201302530  0.276
2018 Häfner S, Burg F, Kannler M, Urban N, Mayer P, Dietrich A, Trauner D, Broichhagen J, Schaefer M. A (+)-larixol congener with high affinity and subtype selectivity towards TRPC6. Chemmedchem. PMID 29522264 DOI: 10.1002/Cmdc.201800021  0.276
2018 Hetzler BE, Volpin G, Vignoni E, Petrovic AG, Proni G, Hu CT, Trauner D. Ein vielseitiges Bisallylbor-Reagenz für die stereoselektive Synthese von chiralen Diolen Angewandte Chemie. 130: 14472-14476. DOI: 10.1002/Ange.201808234  0.274
2019 Trauner D, Matsuura BS. A Rapid Flow Synthesis of Linezolid Synfacts. 15: 827. DOI: 10.1055/S-0039-1689769  0.273
2013 Hager A, Kuttruff CA, Hager D, Terwilliger DW, Trauner D. Toward the total synthesis of divergolides C and D Synlett. 24: 1915-1920. DOI: 10.1055/S-0033-1338974  0.272
2020 Morstein J, Trauner D. Photopharmacological control of lipid function. Methods in Enzymology. 638: 219-232. PMID 32416914 DOI: 10.1016/Bs.Mie.2020.04.025  0.272
2017 Viehrig K, Surup F, Volz C, Herrmann J, Abou Fayad A, Adam S, Köhnke J, Trauner D, Müller R. Structure and Biosynthesis of Crocagins: Polycyclic Postranslationally Modified Ribosomal Peptides from Chondromyces crocatus. Angewandte Chemie (International Ed. in English). PMID 28544148 DOI: 10.1002/Anie.201612640  0.271
2020 Trauner D, Fischer C. Total Synthesis of Heliolactone and its Biological Evaluation in Plants Synfacts. 16: 89. DOI: 10.1055/S-0039-1691385  0.271
2008 Ader C, Schneider R, Hornig S, Velisetty P, Wilson EM, Lange A, Giller K, Ohmert I, Martin-Eauclaire MF, Trauner D, Becker S, Pongs O, Baldus M. A structural link between inactivation and block of a K+ channel. Nature Structural & Molecular Biology. 15: 605-12. PMID 18488040 DOI: 10.1038/Nsmb.1430  0.27
2017 Barber DM, Liu SA, Gottschling K, Sumser M, Hollmann M, Trauner D. Optical control of AMPA receptors using a photoswitchable quinoxaline-2,3-dione antagonist. Chemical Science. 8: 611-615. PMID 28451208 DOI: 10.1039/C6Sc01621A  0.269
2019 Trauner D, Matsuura BS. Chemical Microbiology and Synthesis Reveals the Structure of Colibactin and its Mode of Genotoxicity Synfacts. 15: 1439. DOI: 10.1055/S-0039-1691125  0.269
2020 Trauner D, Shemet A. Bicyclic Sultams Made Easy Synfacts. 16: 97. DOI: 10.1055/S-0039-1691381  0.269
2003 Trauner D. Potassium channels: symmetric, selective, and sensitive. Angewandte Chemie (International Ed. in English). 42: 5671-5. PMID 14661197 DOI: 10.1002/Anie.200301724  0.269
2019 Trauner D, Fischer C. Synthesis, Configuration, and Activity of an Anti-inflammatory Resolving Agonist Synfacts. 15: 309. DOI: 10.1055/S-0037-1612118  0.268
2013 Strych S, Trauner D. Biomimetische Synthese von Santalin A,B und Santarubin A,B, den Hautpigmenten des Roten Sandelholzes† Angewandte Chemie. 125: 9687-9690. DOI: 10.1002/Ange.201302317  0.268
2015 Broichhagen J, Frank JA, Johnston NR, Mitchell RK, Šmid K, Marchetti P, Bugliani M, Rutter GA, Trauner D, Hodson DJ. A red-shifted photochromic sulfonylurea for the remote control of pancreatic beta cell function. Chemical Communications (Cambridge, England). 51: 6018-21. PMID 25744824 DOI: 10.1039/C5Cc01224D  0.268
2019 Morstein J, Trauner D. New players in phototherapy: photopharmacology and bio-integrated optoelectronics. Current Opinion in Chemical Biology. 50: 145-151. PMID 31108317 DOI: 10.1016/J.Cbpa.2019.03.013  0.265
2019 Trauner D, Fischer C. Functionalization and Post-Translational Modification of Cysteines by Tsuji–Trost Reaction Synfacts. 15: 1441. DOI: 10.1055/S-0039-1691128  0.264
2018 Eisel B, Hartrampf F, Meier T, Trauner D. Reversible Optical Control of F1 Fo -ATP Synthase Using Photoswitchable Inhibitors. Febs Letters. PMID 29292505 DOI: 10.1002/1873-3468.12958  0.264
2014 Schönberger M, Trauner D. A photochromic agonist for μ-opioid receptors. Angewandte Chemie (International Ed. in English). 53: 3264-7. PMID 24519993 DOI: 10.1002/Anie.201309633  0.264
2009 Bowie ALJ, Trauner D. ChemInform Abstract: Total Synthesis of (.+-.)-Rhazinal (IXb) Using Novel Palladium-Catalyzed Cyclizations. Cheminform. 40. DOI: 10.1002/CHIN.200927184  0.263
2019 Trauner D, Hetzler B. Synthesis of Aglaroxin C Analogues for Hepatitis C Viral Infection Inhibition Synfacts. 15: 433. DOI: 10.1055/S-0037-1612403  0.263
2014 Auras F, Li Y, Löbermann F, Döblinger M, Schuster J, Peter LM, Trauner D, Bein T. A zinc phthalocyanine based periodic mesoporous organosilica exhibiting charge transfer to fullerenes. Chemistry (Weinheim An Der Bergstrasse, Germany). 20: 14971-5. PMID 25293365 DOI: 10.1002/Chem.201404169  0.263
2019 Trauner D, Hetzler BE. C–N Coupling of Aryl Thianthrenium Salts Synfacts. 15: 1317. DOI: 10.1055/S-0039-1690284  0.261
2019 Trauner D, Shemet A. Short Synthesis of the 3-Deazaguanosine RNA Building Block Synfacts. 15: 941. DOI: 10.1055/S-0039-1689855  0.26
2017 Mehta ZB, Johnston NR, Nguyen-Tu MS, Broichhagen J, Schultz P, Larner DP, Leclerc I, Trauner D, Rutter GA, Hodson DJ. Remote control of glucose homeostasis in vivo using photopharmacology. Scientific Reports. 7: 291. PMID 28331198 DOI: 10.1038/S41598-017-00397-0  0.26
2019 Trauner D, Fischer C. A Highly Selective and Potent Small-Molecule Inhibitor of Factor B Synfacts. 15: 676. DOI: 10.1055/S-0037-1612574  0.258
2017 Hartrampf FWW, Barber DM, Gottschling K, Leippe P, Hollmann M, Trauner D. Development of a photoswitchable antagonist of NMDA receptors Tetrahedron. 73: 4905-4912. DOI: 10.1016/J.Tet.2017.06.056  0.258
2019 Trauner D, Morstein J. Versatile One-Step Approach to Caged Fluorophores Synfacts. 15: 1442. DOI: 10.1055/S-0039-1691129  0.257
2013 Broichhagen J, Trauner D. Bilirubin in a new light. Angewandte Chemie (International Ed. in English). 52: 13868-70. PMID 24353225 DOI: 10.1002/Anie.201307345  0.257
2011 Kuttruff CA, Zipse H, Trauner D. Kompakte Totalsynthese von Variecolortid A und B durch eine ungewöhnliche Hetero‐Diels‐Alder‐Reaktion Angewandte Chemie. 123: 1438-1441. DOI: 10.1002/Ange.201006154  0.254
2015 Broichhagen J, Podewin T, Meyer-Berg H, von Ohlen Y, Johnston NR, Jones BJ, Bloom SR, Rutter GA, Hoffmann-Röder A, Hodson DJ, Trauner D. Optical Control of Insulin Secretion Using an Incretin Switch. Angewandte Chemie (International Ed. in English). PMID 26585495 DOI: 10.1002/Anie.201506384  0.253
2019 Trauner D, Hetzler BE. C–H Activation and Decarboxylative Cross-Coupling of Carboxylic Acids Synfacts. 15: 808. DOI: 10.1055/S-0039-1689765  0.252
2018 DuBay KH, Iwan K, Osorio-Planes L, Geissler PL, Groll M, Trauner D, Broichhagen J. A predictive approach for the optical control of carbonic anhydrase II activity. Acs Chemical Biology. PMID 29357237 DOI: 10.1021/Acschembio.7B00862  0.252
2006 Trauner D, Roethle P. Synthesis of (±)-Bipinnatin J Synfacts. 2006: 0539-0539. DOI: 10.1055/S-2006-934481  0.252
2019 Trauner D, Reyes JR. Synthesis of AWZ1066S, an anti-Wolbachia Drug Candidate Synfacts. 15: 436. DOI: 10.1055/S-0037-1612405  0.252
2013 Li Y, Auras F, Löbermann F, Döblinger M, Schuster J, Peter L, Trauner D, Bein T. A photoactive porphyrin-based periodic mesoporous organosilica thin film. Journal of the American Chemical Society. 135: 18513-9. PMID 24191640 DOI: 10.1021/Ja4082028  0.252
2019 Trauner D, Matsuura BS. A Hydrolytically Stable Analog of Decitabine Synfacts. 15: 1068. DOI: 10.1055/S-0039-1690607  0.251
2019 Trauner D, Reyes JR. Synthesis of a Fluorescent Probe for Cell Surface Phosphatidylserine Synfacts. 15: 440. DOI: 10.1055/S-0037-1612406  0.251
2012 Hog DT, Mayer P, Trauner D. A unified approach to trans-hydrindane sesterterpenoids. The Journal of Organic Chemistry. 77: 5838-43. PMID 22651375 DOI: 10.1021/Jo300726Z  0.25
2012 Stein M, Middendorp SJ, Carta V, Pejo E, Raines DE, Forman SA, Sigel E, Trauner D. Azo-propofols: photochromic potentiators of GABA(A) receptors. Angewandte Chemie (International Ed. in English). 51: 10500-4. PMID 22968919 DOI: 10.1002/Anie.201205475  0.248
2019 Trauner D, Matsuura BS. A Route to Complex N-Arylated Alkylamines via Photocatalytic C–H Amination Synfacts. 15: 812. DOI: 10.1055/S-0039-1689768  0.248
2017 Leippe P, Koehler Leman J, Trauner D. Specificity and Speed: Tethered Photopharmacology. Biochemistry. PMID 28876905 DOI: 10.1021/Acs.Biochem.7B00687  0.247
2006 Trauner D, Lumb J. Synthesis of Microphyllaquinone Synfacts. 2006: 0415-0415. DOI: 10.1055/S-2006-934397  0.247
2020 Trauner D, Morstein J. A Photosensitive Cyclic Acetal Enables Efficient Photo-release of 1,3-Diol 2-Arachidonoylglycerol Synfacts. 16: 101. DOI: 10.1055/S-0039-1691386  0.246
2020 Trauner D, Fischer C. Natural-Product-Inspired Covalent Telomerase Inhibitors Synfacts. 16: 597. DOI: 10.1055/S-0040-1707496  0.246
2020 Trauner D, Ruehmann K. A Carbapenemase Probe that Switches on the Light Synfacts. 16: 472. DOI: 10.1055/S-0040-1707574  0.246
2010 Trauner D. Synthesis: Editorial Synthesis. I-II. DOI: 10.1055/s-0029-1218833  0.245
2016 Broichhagen J, Johnston NR, von Ohlen Y, Meyer-Berg H, Jones BJ, Bloom SR, Rutter GA, Trauner D, Hodson DJ. Allosterische optische Steuerung eines Klasse-B-G-Protein-gekoppelten Rezeptors Angewandte Chemie. 128: 5961-5965. DOI: 10.1002/Ange.201600957  0.245
2020 Müller-Deku A, Meiring JCM, Loy K, Kraus Y, Heise C, Bingham R, Jansen KI, Qu X, Bartolini F, Kapitein LC, Akhmanova A, Ahlfeld J, Trauner D, Thorn-Seshold O. Photoswitchable paclitaxel-based microtubule stabilisers allow optical control over the microtubule cytoskeleton. Nature Communications. 11: 4640. PMID 32934232 DOI: 10.1038/S41467-020-18389-6  0.244
2020 Trauner D, Shemet A. Sulfo-Click Conjugation Synfacts. 16: 600. DOI: 10.1055/S-0040-1707489  0.244
2018 Bamberg E, Gärtner W, Trauner D. Introduction: Optogenetics and Photopharmacology. Chemical Reviews. 118: 10627-10628. PMID 30424609 DOI: 10.1021/Acs.Chemrev.8B00483  0.244
2019 Trauner D, Morstein J. Clickable FPP/GGPP Analogues Enable Analysis of Prenylome Synfacts. 15: 679. DOI: 10.1055/S-0037-1612572  0.243
2010 Trauner D, Danishefsky SJ. ChemInform Abstract: Studies Towards the Total Synthesis of Halichlorine: Asymmetric Synthesis of the Spiroquinolizidine Subunit. Cheminform. 30: no-no. DOI: 10.1002/CHIN.199950213  0.242
2020 Trauner D, Impastato AC. Optical Control of CENP-E Function Synfacts. 16: 474. DOI: 10.1055/S-0040-1707563  0.242
2019 Trauner D, Shemet A. Conformational Restricted Cyclopropanated Nucleoside Derivatives Synfacts. 15: 1320. DOI: 10.1055/S-0039-1690283  0.242
2017 Cheng B, Trauner D, Shchepakin D, Kavanaugh MP. A Photoswitchable Inhibitor of a Glutamate Transporter. Acs Chemical Neuroscience. PMID 28414419 DOI: 10.1021/Acschemneuro.7B00072  0.241
2013 Izquierdo-Serra M, Trauner D, Llobet A, Gorostiza P. Optical control of calcium-regulated exocytosis. Biochimica Et Biophysica Acta. 1830: 2853-60. PMID 23178861 DOI: 10.1016/J.Bbagen.2012.11.003  0.241
2020 Trauner D, Hetzler BE. cGAS/STING Antagonist Discovered in Butenolide Dimer Library Synfacts. 16: 602. DOI: 10.1055/S-0040-1707490  0.241
2014 Middendorp SJ, Hurni E, Schönberger M, Stein M, Pangerl M, Trauner D, Sigel E. Relative positioning of classical benzodiazepines to the γ2-subunit of GABAA receptors. Acs Chemical Biology. 9: 1846-53. PMID 24918742 DOI: 10.1021/Cb500186A  0.239
2010 Löbermann F, Mayer P, Trauner D. Biomimetische Synthese von (−)‐Pycnanthuchinon C über eine Vinylchinon‐Diels‐Alder‐Reaktion Angewandte Chemie. 122: 6335-6338. DOI: 10.1002/Ange.201001862  0.238
2019 Trauner D, Fischer C. A Small-Molecule Inhibitor of C5 Complement Protein Synfacts. 15: 1062. DOI: 10.1055/S-0039-1690610  0.238
2014 Wolter T, Steinbrecher T, Trauner D, Elstner M. Ligand photo-isomerization triggers conformational changes in iGluR2 ligand binding domain. Plos One. 9: e92716. PMID 24713651 DOI: 10.1371/Journal.Pone.0092716  0.237
2019 Trauner D. A Nimbolide-Derived PROTAC Synfacts. 15: 311. DOI: 10.1055/S-0037-1612110  0.236
2019 Trauner D, Matsuura BS. Functionalization of Palladium Oxidative Addition Complexes Derived From Pharmaceuticals Synfacts. 2019: 559. DOI: 10.1055/S-0037-1612498  0.236
2020 Trauner D, Matsuura BS. Poppin’ Open Propellanes Synfacts. 16: 595. DOI: 10.1055/S-0040-1707491  0.235
2015 Broichhagen J, Woodmansee DH, Trauner D, Mayer P. Crystal structure of (E)-1,2-bis-(4-bromo-2,6-di-fluoro-phen-yl)diazene. Acta Crystallographica. Section E, Crystallographic Communications. 71: o459-60. PMID 26279907 DOI: 10.1107/S2056989015010622  0.235
2017 Trauner D. The Chemist and the Architect. Angewandte Chemie (International Ed. in English). PMID 29281154 DOI: 10.1002/Anie.201708325  0.235
2020 Trauner D, Arp CJ. TREK Channel Family Activator for Relief of Pain and Neurogenic Inflammation Synfacts. 16: 720. DOI: 10.1055/S-0040-1706958  0.234
2008 Kienzler MA, Suseno S, Trauner D. ChemInform Abstract: Vinyl Quinones as Diels-Alder Dienes: Concise Synthesis of (-)-Halenaquinone (III) Cheminform. 39. DOI: 10.1002/CHIN.200847209  0.234
2020 Trauner D, Impastato AC. Staudinger Reduction-Activated Lysine for the Control of Protein Subcellular Localization and SUMOylation Synfacts. 16: 349. DOI: 10.1055/S-0039-1691713  0.234
2020 Trauner D, Arp CJ. Reversible Spatiotemporal Control of Induced Protein Degradation by Bistable PhotoPROTACs Synfacts. 16: 589. DOI: 10.1055/S-0040-1707494  0.232
2017 Schmid M, Trauner D. Innenrücktitelbild: Biomimetische Synthese komplexer Flavonoide isoliert aus Daemonorops -“Drachenblut” (Angew. Chem. 40/2017) Angewandte Chemie. 129: 12545-12545. DOI: 10.1002/Ange.201708380  0.232
2020 Trauner D, Arp CJ. Potent and Selective Acid Sphingomyelinase Inhibitors with Antidepressant Activity Synfacts. 16: 466. DOI: 10.1055/S-0040-1707572  0.232
2014 Schönberger M, Trauner D. Ein photochromer Agonist für μ-Opioidrezeptoren Angewandte Chemie. 126: 3329-3332. DOI: 10.1002/Ange.201309633  0.232
2019 Trauner D, Morstein J. Fixing a Photosensitizer Unlocks and Localizes Its Lethality. Acs Central Science. 5: 1636-1638. PMID 31660430 DOI: 10.1021/Acscentsci.9B00887  0.232
2016 Broichhagen J, Klingl YE, Trauner D, Mayer P. 6-[6-(Pyridin-2-yl)-1,2,4,5-tetra-zin-3-yl]pyridin-3-amine monohydrate. Acta Crystallographica. Section E, Crystallographic Communications. 72: 238-40. PMID 26958397 DOI: 10.1107/S2056989016000608  0.231
2019 Trauner D, Shemet A. Copper-Catalyzed ortho-Radiofluorination of Aromatic C–H Bonds Synfacts. 15: 312. DOI: 10.1055/S-0037-1612112  0.23
2015 Simon S, Schell U, Heuer N, Hager D, Albers MF, Matthias J, Fahrnbauer F, Trauner D, Eichinger L, Hedberg C, Hilbi H. Inter-kingdom Signaling by the Legionella Quorum Sensing Molecule LAI-1 Modulates Cell Migration through an IQGAP1-Cdc42-ARHGEF9-Dependent Pathway. Plos Pathogens. 11: e1005307. PMID 26633832 DOI: 10.1371/Journal.Ppat.1005307  0.23
2005 Grundl MA, Kennedy-Smith JJ, Trauner D. Rational design of a chiral palladium(0) olefin complex of unprecedented stability Organometallics. 24: 2831-2833. DOI: 10.1021/Om050277D  0.23
2019 Trauner D, Fischer C. Structure-Guided Discovery of Selective Mcl-1 Inhibitors Synfacts. 15: 1188. DOI: 10.1055/S-0039-1690939  0.229
2010 Stawski P, Janovjak H, Trauner D. Pharmacology of ionotropic glutamate receptors: A structural perspective. Bioorganic & Medicinal Chemistry. 18: 7759-72. PMID 20947363 DOI: 10.1016/J.Bmc.2010.09.012  0.228
2016 Meier R, Trauner D. ChemInform Abstract: A Synthesis of (.+-.)-Aplydactone. Cheminform. 47. DOI: 10.1002/CHIN.201652390  0.228
2017 Volpin G, Vepřek NA, Bellan AB, Trauner D. Enantioselektive Synthese und Racemisierung von (−)‐Sinoracutin Angewandte Chemie. 129: 916-920. DOI: 10.1002/Ange.201608206  0.227
2020 Trauner D, Shemet A. Natural PDE4 Inhibitor Toddacoumalone Synfacts. 16: 346. DOI: 10.1055/S-0039-1691715  0.227
2015 Hog DT, Huber FME, Mayer P, Trauner D. ChemInform Abstract: The Total Synthesis of (-)-Nitidasin. Cheminform. 46: no-no. DOI: 10.1002/CHIN.201506230  0.227
2014 Hager A, Kuttruff CA, Herrero-Gomez E, Trauner D. ChemInform Abstract: Toward the Total Synthesis of Ansalactam A (I). Cheminform. 45: no-no. DOI: 10.1002/CHIN.201421237  0.227
2014 Hog DT, Huber FME, Mayer P, Trauner D. Die Totalsynthese von (−)‐Nitidasin Angewandte Chemie. 126: 8653-8657. DOI: 10.1002/Ange.201403605  0.227
2019 Trauner D, Hetzler BE. Modification of Phosphinopeptidic Scaffolds by Giese-Type Alkylation Synfacts. 15: 680. DOI: 10.1055/S-0037-1612576  0.226
2015 Maryasin B, Olbrich M, Trauner D, Ochsenfeld C. Calculated Nuclear Magnetic Resonance Spectra of Polytwistane and Related Hydrocarbon Nanorods. Journal of Chemical Theory and Computation. 11: 1020-6. PMID 26579754 DOI: 10.1021/Ct5011505  0.225
2019 Trauner D, Fischer C. Photocatalytic Defluoroalkylation of Unactivated Trifluoromethylarenes Synfacts. 15: 1192. DOI: 10.1055/S-0039-1690938  0.225
2014 Calik M, Auras F, Salonen LM, Bader K, Grill I, Handloser M, Medina DD, Dogru M, Löbermann F, Trauner D, Hartschuh A, Bein T. Extraction of photogenerated electrons and holes from a covalent organic framework integrated heterojunction. Journal of the American Chemical Society. 136: 17802-7. PMID 25412210 DOI: 10.1021/Ja509551M  0.224
2013 Beaulieu ED, Ionescu M, Chatterjee S, Yokota K, Trauner D, Lindow S. Characterization of a diffusible signaling factor from Xylella fastidiosa. Mbio. 4: e00539-12. PMID 23300249 DOI: 10.1128/Mbio.00539-12  0.224
2012 Seidel SA, Wienken CJ, Geissler S, Jerabek-Willemsen M, Duhr S, Reiter A, Trauner D, Braun D, Baaske P. Label-free microscale thermophoresis discriminates sites and affinity of protein-ligand binding. Angewandte Chemie (International Ed. in English). 51: 10656-9. PMID 23001866 DOI: 10.1002/Anie.201204268  0.223
2012 Schröckeneder A, Stichnoth D, Mayer P, Trauner D. The crystal structure of the Dess-Martin periodinane. Beilstein Journal of Organic Chemistry. 8: 1523-7. PMID 23019487 DOI: 10.3762/Bjoc.8.172  0.223
2015 Schell U, Simon S, Sahr T, Hager D, Albers MF, Kessler A, Fahrnbauer F, Trauner D, Hedberg C, Buchrieser C, Hilbi H. The α-hydroxyketone LAI-1 regulates motility, Lqs-dependent phosphorylation signaling and gene expression of Legionella pneumophila. Molecular Microbiology. PMID 26538361 DOI: 10.1111/Mmi.13265  0.223
2020 Trauner D, Ruehmann K. Synthetic Cystobactamid Antibiotics With Improved Activities Synfacts. 16: 975. DOI: 10.1055/S-0040-1706825  0.222
2020 Trauner D, Novak AJE. C–H Trifluoromethylation Enabled by a Combination of Decatungstate and Copper Catalysis Synfacts. 16: 717. DOI: 10.1055/S-0040-1706949  0.221
2019 Trauner D, Matsuura BS. An Aromatic Brønsted Acid Catalyst for the Direct Glycosylation of Amides Synfacts. 15: 1318. DOI: 10.1055/S-0039-1690287  0.221
2017 Viehrig K, Surup F, Volz C, Herrmann J, Fayad AA, Adam S, Köhnke J, Trauner D, Müller R. Chemische Struktur und Biosynthese der Crocagine, polycyclischer Peptide ribosomalen Ursprungs aus Chondromyces crocatus Angewandte Chemie. 129: 7513-7517. DOI: 10.1002/Ange.201612640  0.221
2020 Kopf A, Renkawitz J, Hauschild R, Girkontaite I, Tedford K, Merrin J, Thorn-Seshold O, Trauner D, Häcker H, Fischer KD, Kiermaier E, Sixt M. Microtubules control cellular shape and coherence in amoeboid migrating cells. The Journal of Cell Biology. 219. PMID 32379884 DOI: 10.1083/Jcb.201907154  0.22
2019 Trauner D, Morstein J. A New Class of Stimulator of Interferon Genes Receptor Agonists Synfacts. 15: 305. DOI: 10.1055/S-0037-1612121  0.219
2020 Trauner D, Impastato AC. Structure-Guided Design of ABA Receptor Agonists for the Control of Plant Water Use Synfacts. 16: 99. DOI: 10.1055/S-0039-1691379  0.219
2019 Trauner D, Vepřek NA. Late-Stage Functionalization of Complex Primary Sulfonamides via NHC Catalysis Synfacts. 15: 431. DOI: 10.1055/S-0037-1612402  0.219
2019 Trauner D, Hüll K. SCOTfluors: Small, Conjugatable, Orthogonal, and Tunable Fluorophores Synfacts. 15: 942. DOI: 10.1055/S-0039-1689860  0.218
2014 Meier R, Strych S, Trauner D. ChemInform Abstract: Biomimetic Synthesis of (.+-.)-Merochlorin B. Cheminform. 45: no-no. DOI: 10.1002/CHIN.201442220  0.218
2020 Trauner D, Vepřek NA. A Highly Selective Inhibitor of TBK1/IKKε Synfacts. 16: 343. DOI: 10.1055/S-0039-1690343  0.218
2020 Trauner D, Roßmann K. A Conversation with Gerhard Bringmann. Acs Central Science. 6: 1248-1252. PMID 32875065 DOI: 10.1021/Acscentsci.0C00388  0.218
2020 Trauner D, Shemet A. Protein Modification by Cope Rearrangement Synfacts. 16: 465. DOI: 10.1055/S-0040-1707565  0.217
2017 Eguchi K, Taoufiq Z, Thorn-Seshold O, Trauner D, Hasegawa M, Takahashi T. Wild-type monomeric α-synuclein can impair vesicle endocytosis and synaptic fidelity via tubulin polymerization at the calyx of Held. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 28576942 DOI: 10.1523/Jneurosci.0179-17.2017  0.217
2019 Trauner D, Vepřek NA. LYTACs for the Degradation of Secreted and Membrane Proteins Synfacts. 15: 671. DOI: 10.1055/S-0037-1612570  0.217
2019 Trauner D, Hetzler B. Organophotoredox-Catalyzed Sulfoximidation of Electron-Rich Arenes Synfacts. 15: 307. DOI: 10.1055/S-0037-1612115  0.217
2020 Trauner D, Vepřek NA. Potent and Selective Inhibitors of Kallikrein-Related Peptidase 6 Synfacts. 16: 224. DOI: 10.1055/S-0039-1691633  0.217
2019 Trauner D, Vepřek NA. Photocontrol of a Membrane Nanopore Forming Protein Synfacts. 15: 1437. DOI: 10.1055/S-0039-1691131  0.217
2019 Trauner D, Reyes JR. A Fluorinated Carbocyclic Nucleoside with Anti-HBV Activity Synfacts. 15: 308. DOI: 10.1055/S-0037-1612117  0.217
2019 Petkov BK, Gellen TA, Farfan CA, Carbery WP, Hetzler BE, Trauner D, Li X, Glover WJ, Ulness DJ, Turner DB. Two-Dimensional Electronic Spectroscopy Reveals the Spectral Dynamics of Förster Resonance Energy Transfer Chem. 5: 2111-2125. DOI: 10.1016/J.Chempr.2019.05.005  0.216
2019 Kol M, Williams B, Toombs-Ruane H, Franquelim HG, Korneev S, Schroeer C, Schwille P, Trauner D, Holthuis JC, Frank JA. Author response: Optical manipulation of sphingolipid biosynthesis using photoswitchable ceramides Elife. DOI: 10.7554/Elife.43230.026  0.216
2020 Trauner D, Fischer C. Replacing HN3 with Nitromethane for Schmidt-Type Formation of Amides and Nitriles Synfacts. 16: 467. DOI: 10.1055/S-0040-1707571  0.216
2019 Quintela-Varela H, Jamieson C, Shao Q, Houk K, Trauner D. Bioinspired Synthesis of (-)-PF-1018. Angewandte Chemie (International Ed. in English). PMID 31788926 DOI: 10.1002/Anie.201912452  0.215
2015 Trauner D. Richard Willstätter and the 1915 Nobel Prize in Chemistry. Angewandte Chemie (International Ed. in English). 54: 11910-6. PMID 26291186 DOI: 10.1002/Anie.201505507  0.215
2012 Abrams ZR, Warrier A, Wang Y, Trauner D, Zhang X. Tunable oscillations in the Purkinje neuron. Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics. 85: 041905. PMID 22680496 DOI: 10.1103/Physreve.85.041905  0.215
2015 Schneider LS, von Schwarzenberg K, Lehr T, Ulrich M, Kubisch-Dohmen R, Liebl J, Trauner D, Menche D, Vollmar AM. Vacuolar-ATPase Inhibition Blocks Iron Metabolism to Mediate Therapeutic Effects in Breast Cancer. Cancer Research. 75: 2863-74. PMID 26018087 DOI: 10.1158/0008-5472.Can-14-2097  0.215
2019 Trauner D, Fischer C. Near-IR Polymethine Fluorophores Absorbing Beyond 1000 nm Synfacts. 15: 315. DOI: 10.1055/S-0037-1612119  0.215
2020 Trauner D, Ruehmann K. Biosynthetic Engineering of Polyketide Synthase Modules Towards New Enacyloxin Antibiotics Synfacts. 16: 225. DOI: 10.1055/S-0039-1691641  0.215
2020 Trauner D, Hetzler BE. Photocaged Dopamine Receptor Ligands Synfacts. 16: 723. DOI: 10.1055/S-0040-1706953  0.215
2019 Trauner D, Reynders M. Small-Molecule Inhibitors of CRISPR-Cas9 Synfacts. 15: 936. DOI: 10.1055/S-0039-1689861  0.214
2020 Trauner D, Ruehmann K. Irreversible Covalent Inhibition of TrxR1 Prevents STAT3-Dependent Transcription Activation Synfacts. 16: 718. DOI: 10.1055/S-0040-1706962  0.214
2019 Trauner D, Matsuura BS. Late-Stage Negishi Coupling of Peptides Synfacts. 15: 675. DOI: 10.1055/S-0037-1612568  0.214
2014 Broichhagen J, Jurastow I, Iwan K, Kummer W, Trauner D. Optische Kontrolle der Acetylcholinesterase mit einem schaltbaren Tacrin Angewandte Chemie. 126: 7788-7792. DOI: 10.1002/Ange.201403666  0.214
2020 Trauner D, Matuura BS. In Vivo Optochemical Control of Glutamate Receptors with Cloaked Glutamates Synfacts. 16: 725. DOI: 10.1055/S-0040-1706954  0.213
2022 Ko T, Oliveira MM, Alapin JM, Morstein J, Klann E, Trauner D. Optical Control of Translation with a Puromycin Photoswitch. Journal of the American Chemical Society. PMID 36394560 DOI: 10.1021/jacs.2c07374  0.213
2020 Trauner D, Shemet A. DNA-Compatible Conversion of Primary Amines into Azides Synfacts. 16: 221. DOI: 10.1055/S-0039-1691634  0.213
2008 Trauner D. Introduction: Chemical approaches to neurobiology. Chemical Reviews. 108: 1499-500. PMID 18476670 DOI: 10.1021/Cr800273N  0.213
2012 Stawski P, Sumser M, Trauner D. A photochromic agonist of AMPA receptors. Angewandte Chemie (International Ed. in English). 51: 5748-51. PMID 22517577 DOI: 10.1002/Anie.201109265  0.212
2019 Trauner D, Shemet A. New Methods to Access DNA-Encoded Libraries (DELs) Synfacts. 2019: 565. DOI: 10.1055/S-0037-1612508  0.212
2020 Trauner D, Novak AJE. A Versatile Cellular Target Engagement Probe for MPC2 Synfacts. 16: 345. DOI: 10.1055/S-0039-1691714  0.211
2019 Trauner D, Matsuura BS. Chemical Protein Degradation Targeting Non-Functional Binding Sites Synfacts. 15: 1070. DOI: 10.1055/S-0039-1690608  0.211
2019 Trauner D, Morstein J. Targeted Degradation of Extracellular Proteins with ENDTACs Synfacts. 15: 1193. DOI: 10.1055/S-0039-1690940  0.21
2019 Trauner D, Shemet A. Four New DNA Building Blocks Synfacts. 2019: 555. DOI: 10.1055/S-0037-1612507  0.21
2013 von Schwarzenberg K, Wiedmann RM, Oak P, Schulz S, Zischka H, Wanner G, Efferth T, Trauner D, Vollmar AM. Mode of cell death induction by pharmacological vacuolar H+-ATPase (V-ATPase) inhibition. The Journal of Biological Chemistry. 288: 1385-96. PMID 23168408 DOI: 10.1074/Jbc.M112.412007  0.209
2020 Trauner D, Arp CJ. A Positive Allosteric Modulator of the Human Dopamine D1 Receptor Synfacts. 16: 100. DOI: 10.1055/S-0039-1691383  0.209
2020 Trauner D, Morstein J. Bioinspired Nucleobase Caging Synfacts. 16: 347. DOI: 10.1055/S-0039-1690341  0.209
2019 Trauner D, Hetzler BE. A Reagent for Doubly Bioorthogonal Cysteine Labeling Synfacts. 15: 1190. DOI: 10.1055/S-0039-1690936  0.209
2019 Trauner D, Matsuura BS. Agnostic Screening of Sulfonyl Fluoride Fragments to Generate Selective Covalent Inhibitors Synfacts. 15: 1436. DOI: 10.1055/S-0039-1691126  0.209
2020 Trauner D, Matsuura BS. Lasonolide A is a Prodrug Activated by LDAH, a Serine Hydrolase Synfacts. 16: 468. DOI: 10.1055/S-0040-1707568  0.209
2019 Trauner D, Matsuura BS. SPiDER-Killer-βGal: A Photosensitizer for Targeted Cell Ablation with Single-Cell Resolution Synfacts. 15: 1321. DOI: 10.1055/S-0039-1690286  0.208
2020 Trauner D, Arp CJ. Cell-Type-Specific Voltage Imaging Using Covalently Tethered Fluorophores Synfacts. 16: 344. DOI: 10.1055/S-0039-1690340  0.208
2019 Trauner D, Shemet A. Selective α-Glycosidation of Sialic Acid Synfacts. 15: 940. DOI: 10.1055/S-0039-1689856  0.208
2019 Trauner D, Shemet A. Sulfonium Sugars with Antidiabetic Activities Synfacts. 15: 804. DOI: 10.1055/S-0039-1689763  0.208
2019 Trauner D, Fischer C. Highly Selective Insulin-Degrading Enzyme Inhibitors Synfacts. 15: 939. DOI: 10.1055/S-0039-1689858  0.208
2020 Trauner D, Arp CJ. α-Ketoamide Inhibitors of SARS-CoV-2 Main Protease Synfacts. 16: 713. DOI: 10.1055/S-0040-1706957  0.208
2020 Trauner D, Fischer C. Cyclic Naphthoquinone Imine Based Antagonists of the RIG-I Innate Immune Receptor Synfacts. 16: 473. DOI: 10.1055/S-0040-1707570  0.208
2014 Trauner D. Finding function and form. Natural Product Reports. 31: 411-3. PMID 24595414 DOI: 10.1039/C4Np90008A  0.207
2020 Trauner D, Reynders M. Introducing Phosphatase-Recruiting Chimeras Synfacts. 16: 594. DOI: 10.1055/S-0040-1707495  0.207
2016 Johnston NR, Mitchell RK, Haythorne E, Pessoa MP, Semplici F, Ferrer J, Piemonti L, Marchetti P, Bugliani M, Bosco D, Berishvili E, Duncanson P, Watkinson M, Broichhagen J, Trauner D, et al. Beta Cell Hubs Dictate Pancreatic Islet Responses to Glucose. Cell Metabolism. PMID 27452146 DOI: 10.1016/J.Cmet.2016.06.020  0.206
2012 Wiedmann RM, von Schwarzenberg K, Palamidessi A, Schreiner L, Kubisch R, Liebl J, Schempp C, Trauner D, Vereb G, Zahler S, Wagner E, Müller R, Scita G, Vollmar AM. The V-ATPase-inhibitor archazolid abrogates tumor metastasis via inhibition of endocytic activation of the Rho-GTPase Rac1. Cancer Research. 72: 5976-87. PMID 22986742 DOI: 10.1158/0008-5472.Can-12-1772  0.206
2020 Trauner D, Vepřek NA. A Potential anti-Pertussis Vaccine Based on Lipopolysaccharide Endotoxins of B. pertussis Synfacts. 16: 471. DOI: 10.1055/S-0040-1707573  0.205
2020 Trauner D, Hetzler BE. A Classic Way of Forming Amide Bonds Synfacts. 16: 475. DOI: 10.1055/S-0040-1707567  0.205
2020 Trauner D, Impastato AC. Salinipostin A Probe Identifies Potential Antimalarial Protein Targets Synfacts. 16: 590. DOI: 10.1055/S-0040-1707486  0.205
2020 Trauner D, Hetzler BE. Enantiomeric Probe Pairs for Ligandable Proteome Mapping Synfacts. 16: 98. DOI: 10.1055/S-0039-1691382  0.205
2017 Schmid M, Trauner D. Biomimetische Synthese komplexer Flavonoide isoliert aus Daemonorops-“Drachenblut” Angewandte Chemie. 129: 12500-12504. DOI: 10.1002/Ange.201705390  0.205
2019 Trauner D, Hüll K. An in Vivo Mass Cytometry Probe for Protein Translation Synfacts. 15: 803. DOI: 10.1055/S-0039-1689758  0.205
2019 Trauner D, Reynders M. Dual Inhibitors of Anaplastic Lymphoma Kinase and Bromodomain‑4 Synfacts. 15: 678. DOI: 10.1055/S-0037-1612569  0.204
2023 Morstein J, Amatuni A, Shuster A, Kuttenlochner W, Ko T, Abegg D, Groll M, Adibekian A, Renata H, Trauner D. Optical Control of Proteasomal Protein Degradation with a Photoswitchable Lipopeptide. Angewandte Chemie (International Ed. in English). e202314791. PMID 38109686 DOI: 10.1002/anie.202314791  0.204
2012 Hager D, Mayer P, Paulitz C, Tiebes J, Trauner D. Stereoselektive Totalsynthese von Herbicidin C und Aureonuclemycin durch späte N-Glykosylierung Angewandte Chemie. 124: 6631-6634. DOI: 10.1002/Ange.201201826  0.204
2010 Trauner D. Chemical neurobiology--introduction. Bioorganic & Medicinal Chemistry. 18: 7715. PMID 21040857 DOI: 10.1016/J.Bmc.2010.10.051  0.204
2020 Trauner D, Arp CJ. Dual Inhibitors of OGG1/NUDT1 for Probing Disease States Synfacts. 16: 223. DOI: 10.1055/S-0039-1691638  0.204
2019 Trauner D, Morstein J. Organelle-Targeted Membrane Tension Probes Synfacts. 2019: 556. DOI: 10.1055/S-0037-1612501  0.204
2019 Trauner D, Reynders M. Antimalarial 1,2,4-Triazine Dimers Synfacts. 2019: 564. DOI: 10.1055/S-0037-1612505  0.204
2017 Hartrampf FWW, Furukawa T, Trauner D. Eine Conia‐En‐artige Cyclisierung unter basischen Bedingungen ermöglicht die effiziente Synthese von (−)‐Lycoposerramin R Angewandte Chemie. 129: 912-915. DOI: 10.1002/Ange.201610021  0.203
2022 Crea F, Vorkas A, Redlich A, Cruz R, Shi C, Trauner D, Lange A, Schlesinger R, Heberle J. Photoactivation of a Mechanosensitive Channel. Frontiers in Molecular Biosciences. 9: 905306. PMID 35836929 DOI: 10.3389/fmolb.2022.905306  0.203
2019 Trauner D, Fischer C. Targetable, Bright Small-Molecule Ca2+ Indicators Synfacts. 15: 1313. DOI: 10.1055/S-0039-1690288  0.203
2019 Trauner D, Fischer C. Specific Functionalization of Cysteine and Lysine Using Dinitroimidazoles Synfacts. 15: 430. DOI: 10.1055/S-0037-1612410  0.203
2019 Trauner D, Morstein J. Membrane Probes for Super-Resolution Imaging of Plasma Membranes Synfacts. 15: 1315. DOI: 10.1055/S-0039-1690290  0.203
2012 Stawski P, Sumser M, Trauner D. Ein photochromer Agonist für AMPA‐Rezeptoren Angewandte Chemie. 124: 5847-5850. DOI: 10.1002/Ange.201109265  0.202
2019 Trauner D, Shemet A. Application of Hemithioindigo Photoswitches in Photopharmacology Synfacts. 15: 432. DOI: 10.1055/S-0037-1612401  0.202
2020 Trauner D, Matsuura BS. A First-in-Class, Clinically-Relevant Covalent Inhibitor of KRAS(G12C) Synfacts. 16: 220. DOI: 10.1055/S-0039-1691636  0.202
2019 Trauner D, Fischer C. Merging Indole and Morphan Fragments to Form Potent Glucose Transporter Inhibitors Synfacts. 15: 1440. DOI: 10.1055/S-0039-1691127  0.202
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