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H. Ronald Kaback - Publications

Affiliations: 
University of California, Los Angeles, Los Angeles, CA 
Area:
Kabackosomes
Website:
http://149.142.237.181/index.html
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347 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Hariharan P, Shi Y, Katsube S, Willibal K, Burrows ND, Mitchell P, Bakhtiiari A, Stanfield S, Pardon E, Kaback HR, Liang R, Steyaert J, Viner R, Guan L. Mobile barrier mechanisms for Na-coupled symport in an MFS sugar transporter. Elife. 12. PMID 38381130 DOI: 10.7554/eLife.92462  0.363
2023 Hariharan P, Shi Y, Katsube S, Willibal K, Burrows ND, Mitchell P, Bakhtiiari A, Stanfield S, Pardon E, Kaback HR, Liang R, Steyaert J, Viner R, Guan L. Mimicking the regulatory state of a major facilitator superfamily sugar transporter. Biorxiv : the Preprint Server For Biology. PMID 37790566 DOI: 10.1101/2023.09.18.558283  0.646
2023 Katsube S, Willibal K, Vemulapally S, Hariharan P, Tikhonova E, Pardon E, Kaback HR, Steyaert J, Guan L. In vivo and in vitro characterizations of melibiose permease (MelB) conformation- dependent nanobodies reveal sugar-binding mechanisms. The Journal of Biological Chemistry. 104967. PMID 37380079 DOI: 10.1016/j.jbc.2023.104967  0.649
2021 Bazzone A, Tesmer L, Kurt D, Kaback HR, Fendler K, Madej MG. Investigation of sugar binding kinetics of the E. coli sugar/H symporter XylE using solid supported membrane-based electrophysiology. The Journal of Biological Chemistry. 101505. PMID 34929170 DOI: 10.1016/j.jbc.2021.101505  0.77
2021 Kaback HR. It's Better To Be Lucky Than Smart. Annual Review of Biochemistry. 90: 1-29. PMID 33472005 DOI: 10.1146/annurev-biochem-011520-105008  0.334
2020 Omeis F, Seica AFS, Ermolova N, Kaback HR, Hellwig P. Monoclonal antibody 4B1 influences the pKa of Glu325 in lactose permease (LacY) from Escherichia coli: evidence from SEIRAS. Febs Letters. 594: 3356-3362. PMID 32780424 DOI: 10.1002/1873-3468.13907  0.386
2020 Kumar H, Finer-Moore J, Smirnova I, Kasho V, Pardon E, Steyaert J, Kaback HR, Stroud RM. Diversity in kinetics correlated with structure in nano body-stabilized LacY. Plos One. 15: e0232846. PMID 32380514 DOI: 10.1371/Journal.Pone.0232846  0.456
2020 Jiang X, Ermolova N, Lim J, Choi SW, Kaback HR. Kinetic Effects of Inside‐Positive Membrane Potential on the Lactose Efflux of LacY The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.02548  0.387
2019 Jiang X, Ermolova N, Lim J, Choi SW, Kaback HR. The proton electrochemical gradient induces a kinetic asymmetry in the symport cycle of LacY. Proceedings of the National Academy of Sciences of the United States of America. PMID 31889006 DOI: 10.1073/Pnas.1916563117  0.465
2019 Kaback HR, Guan L. It takes two to tango: The dance of the permease. The Journal of General Physiology. PMID 31147449 DOI: 10.1085/Jgp.201912377  0.724
2019 Serdiuk T, Steudle A, Mari SA, Manioglu S, Kaback HR, Kuhn A, Müller DJ. Insertion and folding pathways of single membrane proteins guided by translocases and insertases. Science Advances. 5: eaau6824. PMID 30801000 DOI: 10.1126/Sciadv.Aau6824  0.463
2019 Grytsyk N, Santos Seiça AF, Sugihara J, Kaback HR, Hellwig P. Arg302 governs the pK of Glu325 in LacY. Proceedings of the National Academy of Sciences of the United States of America. 116: 4934-4939. PMID 30792352 DOI: 10.1073/Pnas.1820744116  0.494
2019 Kaback HR. DISCUSSION PAPER: BACTERIAL TRANSPORT MECHANISMS AS STUDIED IN CYTOPLASMIC MEMBRANE VESICLES. Annals of the New York Academy of Sciences. 195: 407-411. PMID 29090777 DOI: 10.1111/j.1749-6632.1972.tb54821.x  0.308
2018 Smirnova I, Kasho V, Kaback HR. Engineered occluded apo-intermediate of LacY. Proceedings of the National Academy of Sciences of the United States of America. 115: 12716-12721. PMID 30478058 DOI: 10.1073/Pnas.1816267115  0.502
2018 Kumar H, Finer-Moore JS, Jiang X, Smirnova I, Kasho V, Pardon E, Steyaert J, Kaback HR, Stroud RM. Crystal Structure of a ligand-bound LacY-Nanobody Complex. Proceedings of the National Academy of Sciences of the United States of America. PMID 30108145 DOI: 10.1073/Pnas.1801774115  0.502
2018 Smirnova I, Kasho V, Jiang X, Chen HM, Withers SG, Kaback HR. Oversized galactosides as a probe for conformational dynamics in LacY. Proceedings of the National Academy of Sciences of the United States of America. PMID 29602806 DOI: 10.1073/Pnas.1800706115  0.441
2017 Smirnova IN, Kasho VN, Jiang X, Kaback HR. An asymmetric conformational change in LacY. Biochemistry. PMID 28300394 DOI: 10.1021/Acs.Biochem.7B00134  0.477
2017 Chaptal V, Delolme F, Kilburg A, Magnard S, Montigny C, Picard M, Prier C, Monticelli L, Bornert O, Agez M, Ravaud S, Orelle C, Wagner R, Jawhari A, Broutin I, ... ... Kaback HR, et al. Quantification of Detergents Complexed with Membrane Proteins. Scientific Reports. 7: 41751. PMID 28176812 DOI: 10.1038/Srep41751  0.39
2017 Grytsyk N, Sugihara J, Kaback HR, Hellwig P. pKa of Glu325 in LacY Proceedings of the National Academy of Sciences of the United States of America. 114: 1530-1535. PMID 28154138 DOI: 10.1073/Pnas.1621431114  0.499
2016 Jiang X, Smirnova I, Kasho V, Wu J, Hirata K, Ke M, Pardon E, Steyaert J, Yan N, Kaback HR. Crystal structure of a LacY-nanobody complex in a periplasmic-open conformation. Proceedings of the National Academy of Sciences of the United States of America. PMID 27791182 DOI: 10.1073/Pnas.1615414113  0.513
2016 Hariharan P, Andersson M, Jiang X, Pardon E, Steyaert J, Kaback HR, Guan L. Thermodynamics of nanobody binding to lactose permease. Biochemistry. PMID 27686537 DOI: 10.1021/Acs.Biochem.6B00826  0.665
2016 Serdiuk T, Balasubramaniam D, Sugihara J, Mari SA, Kaback HR, Müller DJ. YidC assists the stepwise and stochastic folding of membrane proteins. Nature Chemical Biology. 12: 911-917. PMID 27595331 DOI: 10.1038/Nchembio.2169  0.466
2016 Jiang X, Andersson M, Chau BT, Wong LY, Villafuerte MK, Kaback HR. Role of conserved Gly-Gly pairs on the periplasmic side of LacY. Biochemistry. PMID 27438891 DOI: 10.1021/Acs.Biochem.6B00666  0.515
2016 Bazzone A, Madej MG, Kaback HR, Fendler K. pH Regulation of Electrogenic Sugar/H+ Symport in MFS Sugar Permeases. Plos One. 11: e0156392. PMID 27227677 DOI: 10.1371/Journal.Pone.0156392  0.728
2016 Parameswaran H, Jiang X, Pardon E, Steyaert J, Kaback HR, Guan L. Thermodynamic Insights into Conformational Dynamics of Sugar Transporters Biophysical Journal. 110: 137a. DOI: 10.1016/J.Bpj.2015.11.784  0.705
2015 Smirnova I, Kasho V, Jiang X, Pardon E, Steyaert J, Kaback HR. Transient conformers of LacY are trapped by nanobodies. Proceedings of the National Academy of Sciences of the United States of America. PMID 26512108 DOI: 10.1073/Pnas.1519485112  0.506
2015 Kumar H, Finer-Moore JS, Kaback HR, Stroud RM. Structure of LacY with an α-substituted galactoside: Connecting the binding site to the protonation site. Proceedings of the National Academy of Sciences of the United States of America. 112: 9004-9. PMID 26157133 DOI: 10.1073/Pnas.1509854112  0.441
2015 Serdiuk T, Sugihara J, Mari SA, Kaback HR, Müller DJ. Observing a lipid-dependent alteration in single lactose permeases. Structure (London, England : 1993). 23: 754-61. PMID 25800555 DOI: 10.1016/J.Str.2015.02.009  0.482
2015 Hariharan P, Balasubramaniam D, Peterkofsky A, Kaback HR, Guan L. Thermodynamic mechanism for inhibition of lactose permease by the phosphotransferase protein IIAGlc. Proceedings of the National Academy of Sciences of the United States of America. 112: 2407-12. PMID 25675534 DOI: 10.1073/Pnas.1500891112  0.67
2015 Kaback HR. A chemiosmotic mechanism of symport. Proceedings of the National Academy of Sciences of the United States of America. 112: 1259-64. PMID 25568085 DOI: 10.1073/Pnas.1419325112  0.548
2014 Smirnova I, Kasho V, Jiang X, Pardon E, Steyaert J, Kaback HR. Outward-facing conformers of LacY stabilized by nanobodies. Proceedings of the National Academy of Sciences of the United States of America. 111: 18548-53. PMID 25512549 DOI: 10.1073/Pnas.1422265112  0.535
2014 Smirnova I, Kasho V, Kaback HR. Real-time conformational changes in LacY. Proceedings of the National Academy of Sciences of the United States of America. 111: 8440-5. PMID 24872451 DOI: 10.1073/Pnas.1408374111  0.409
2014 Serdiuk T, Madej MG, Sugihara J, Kawamura S, Mari SA, Kaback HR, Müller DJ. Substrate-induced changes in the structural properties of LacY. Proceedings of the National Academy of Sciences of the United States of America. 111: E1571-80. PMID 24711390 DOI: 10.1073/Pnas.1404446111  0.792
2014 Madej MG, Sun L, Yan N, Kaback HR. Functional architecture of MFS D-glucose transporters. Proceedings of the National Academy of Sciences of the United States of America. 111: E719-27. PMID 24550316 DOI: 10.1073/Pnas.1400336111  0.74
2014 Jiang X, Villafuerte MK, Andersson M, White SH, Kaback HR. Galactoside-binding site in LacY. Biochemistry. 53: 1536-43. PMID 24520888 DOI: 10.1021/Bi401716Z  0.36
2014 Kumar H, Kasho V, Smirnova I, Finer-Moore JS, Kaback HR, Stroud RM. Structure of sugar-bound LacY. Proceedings of the National Academy of Sciences of the United States of America. 111: 1784-8. PMID 24453216 DOI: 10.1073/Pnas.1324141111  0.505
2014 Ethayathulla AS, Yousef MS, Amin A, Leblanc G, Kaback HR, Guan L. Structure-based mechanism for Na(+)/melibiose symport by MelB. Nature Communications. 5: 3009. PMID 24389923 DOI: 10.1038/Ncomms4009  0.697
2013 Madej MG, Kaback HR. Evolutionary mix-and-match with MFS transporters II. Proceedings of the National Academy of Sciences of the United States of America. 110: E4831-8. PMID 24259711 DOI: 10.1073/pnas.1319754110  0.765
2013 Gaiko O, Bazzone A, Fendler K, Kaback HR. Electrophysiological characterization of uncoupled mutants of LacY. Biochemistry. 52: 8261-6. PMID 24152072 DOI: 10.1021/Bi4013269  0.451
2013 Jiang X, Driessen AJ, Feringa BL, Kaback HR. The periplasmic cavity of LacY mutant Cys154→Gly: how open is open? Biochemistry. 52: 6568-74. PMID 23962108 DOI: 10.1021/Bi401026D  0.533
2013 Zhu L, Kaback HR, Dalbey RE. YidC protein, a molecular chaperone for LacY protein folding via the SecYEG protein machinery. The Journal of Biological Chemistry. 288: 28180-94. PMID 23928306 DOI: 10.1074/Jbc.M113.491613  0.515
2013 Smirnova I, Kasho V, Sugihara J, Kaback HR. Trp replacements for tightly interacting Gly-Gly pairs in LacY stabilize an outward-facing conformation. Proceedings of the National Academy of Sciences of the United States of America. 110: 8876-81. PMID 23671103 DOI: 10.1073/Pnas.1306849110  0.478
2013 Madej MG, Dang S, Yan N, Kaback HR. Evolutionary mix-and-match with MFS transporters. Proceedings of the National Academy of Sciences of the United States of America. 110: 5870-4. PMID 23530251 DOI: 10.1073/Pnas.1303538110  0.791
2012 Smirnova I, Kasho V, Sugihara J, Vázquez-Ibar JL, Kaback HR. Role of protons in sugar binding to LacY. Proceedings of the National Academy of Sciences of the United States of America. 109: 16835-40. PMID 23033496 DOI: 10.1073/Pnas.1214890109  0.391
2012 Madej MG, Soro SN, Kaback HR. Apo-intermediate in the transport cycle of lactose permease (LacY). Proceedings of the National Academy of Sciences of the United States of America. 109: E2970-8. PMID 23012238 DOI: 10.1073/Pnas.1211183109  0.773
2012 Andersson M, Bondar AN, Freites JA, Tobias DJ, Kaback HR, White SH. Proton-coupled dynamics in lactose permease. Structure (London, England : 1993). 20: 1893-904. PMID 23000385 DOI: 10.1016/J.Str.2012.08.021  0.371
2012 Sugihara J, Sun L, Yan N, Kaback HR. Dynamics of the L-fucose/H+ symporter revealed by fluorescence spectroscopy. Proceedings of the National Academy of Sciences of the United States of America. 109: 14847-51. PMID 22930818 DOI: 10.1073/Pnas.1213445109  0.437
2012 Zhou Y, Jiang X, Kaback HR. Role of the irreplaceable residues in the LacY alternating access mechanism. Proceedings of the National Academy of Sciences of the United States of America. 109: 12438-42. PMID 22802658 DOI: 10.1073/pnas.1210684109  0.36
2012 Jiang X, Guan L, Zhou Y, Hong WX, Zhang Q, Kaback HR. Evidence for an intermediate conformational state of LacY. Proceedings of the National Academy of Sciences of the United States of America. 109: E698-704. PMID 22355148 DOI: 10.1073/Pnas.1201107109  0.73
2011 Sugihara J, Smirnova I, Kasho V, Kaback HR. Sugar recognition by CscB and LacY. Biochemistry. 50: 11009-14. PMID 22106930 DOI: 10.1021/Bi201592Y  0.47
2011 Smirnova I, Kasho V, Kaback HR. Lactose permease and the alternating access mechanism. Biochemistry. 50: 9684-93. PMID 21995338 DOI: 10.1021/Bi2014294  0.515
2011 Smirnova I, Kasho V, Sugihara J, Kaback HR. Opening the periplasmic cavity in lactose permease is the limiting step for sugar binding. Proceedings of the National Academy of Sciences of the United States of America. 108: 15147-51. PMID 21896727 DOI: 10.1073/Pnas.1112157108  0.485
2011 Zhou Y, Madej MG, Guan L, Nie Y, Kaback HR. An early event in the transport mechanism of LacY protein: interaction between helices V and I. The Journal of Biological Chemistry. 286: 30415-22. PMID 21730060 DOI: 10.1074/Jbc.M111.268433  0.824
2011 Chaptal V, Kwon S, Sawaya MR, Guan L, Kaback HR, Abramson J. Crystal structure of lactose permease in complex with an affinity inactivator yields unique insight into sugar recognition. Proceedings of the National Academy of Sciences of the United States of America. 108: 9361-6. PMID 21593407 DOI: 10.1073/pnas.1105687108  0.652
2011 Jiang X, Nie Y, Kaback HR. Site-directed alkylation studies with LacY provide evidence for the alternating access model of transport. Biochemistry. 50: 1634-40. PMID 21254783 DOI: 10.1021/Bi101988S  0.49
2011 Kaback HR, Smirnova I, Kasho V, Nie Y, Zhou Y. The alternating access transport mechanism in LacY. The Journal of Membrane Biology. 239: 85-93. PMID 21161516 DOI: 10.1007/S00232-010-9327-5  0.471
2011 Kaback HR. The old Man and the Membrane Biophysical Journal. 100: 513a. DOI: 10.1016/J.Bpj.2010.12.2999  0.48
2010 Garcia-Celma JJ, Ploch J, Smirnova I, Kaback HR, Fendler K. Delineating electrogenic reactions during lactose/H+ symport. Biochemistry. 49: 6115-21. PMID 20568736 DOI: 10.1021/Bi100492P  0.391
2010 Nie Y, Kaback HR. Sugar binding induces the same global conformational change in purified LacY as in the native bacterial membrane. Proceedings of the National Academy of Sciences of the United States of America. 107: 9903-8. PMID 20457922 DOI: 10.1073/Pnas.1004515107  0.533
2010 Liu Z, Madej MG, Kaback HR. Helix dynamics in LacY: helices II and IV. Journal of Molecular Biology. 396: 617-26. PMID 20043916 DOI: 10.1016/J.Jmb.2009.12.044  0.796
2009 Smirnova I, Kasho V, Sugihara J, Kaback HR. Probing of the rates of alternating access in LacY with Trp fluorescence. Proceedings of the National Academy of Sciences of the United States of America. 106: 21561-6. PMID 19959662 DOI: 10.1073/Pnas.0911434106  0.524
2009 Zhou Y, Nie Y, Kaback HR. Residues gating the periplasmic pathway of LacY. Journal of Molecular Biology. 394: 219-25. PMID 19781551 DOI: 10.1016/J.Jmb.2009.09.043  0.524
2009 Guan L, Kaback HR. Properties of a LacY efflux mutant. Biochemistry. 48: 9250-5. PMID 19719233 DOI: 10.1021/Bi9014067  0.711
2009 Smirnova I, Kasho V, Sugihara J, Choe JY, Kaback HR. Residues in the H+ translocation site define the pKa for sugar binding to LacY. Biochemistry. 48: 8852-60. PMID 19689129 DOI: 10.1021/Bi9011918  0.435
2009 Garcia-Celma JJ, Smirnova IN, Kaback HR, Fendler K. Electrophysiological characterization of LacY. Proceedings of the National Academy of Sciences of the United States of America. 106: 7373-8. PMID 19383792 DOI: 10.1073/Pnas.0902471106  0.472
2009 Nie Y, Zhou Y, Kaback HR. Clogging the periplasmic pathway in LacY. Biochemistry. 48: 738-43. PMID 19128028 DOI: 10.1021/Bi801976R  0.521
2008 Smirnova IN, Kasho V, Kaback HR. Protonation and sugar binding to LacY. Proceedings of the National Academy of Sciences of the United States of America. 105: 8896-901. PMID 18567672 DOI: 10.1073/Pnas.0803577105  0.381
2008 Nie Y, Sabetfard FE, Kaback HR. The Cys154-->Gly mutation in LacY causes constitutive opening of the hydrophilic periplasmic pathway. Journal of Molecular Biology. 379: 695-703. PMID 18485365 DOI: 10.1016/J.Jmb.2008.04.015  0.537
2008 Zhou Y, Guan L, Freites JA, Kaback HR. Opening and closing of the periplasmic gate in lactose permease. Proceedings of the National Academy of Sciences of the United States of America. 105: 3774-8. PMID 18319336 DOI: 10.1073/Pnas.0800825105  0.687
2008 Dong Y, Palmer SR, Hasona A, Nagamori S, Kaback HR, Dalbey RE, Brady LJ. Functional overlap but lack of complete cross-complementation of Streptococcus mutans and Escherichia coli YidC orthologs. Journal of Bacteriology. 190: 2458-69. PMID 18178746 DOI: 10.1128/Jb.01366-07  0.761
2007 Smirnova I, Kasho V, Choe JY, Altenbach C, Hubbell WL, Kaback HR. Sugar binding induces an outward facing conformation of LacY. Proceedings of the National Academy of Sciences of the United States of America. 104: 16504-9. PMID 17925435 DOI: 10.1073/Pnas.0708258104  0.476
2007 Nie Y, Ermolova N, Kaback HR. Site-directed alkylation of LacY: effect of the proton electrochemical gradient. Journal of Molecular Biology. 374: 356-64. PMID 17920075 DOI: 10.1016/J.Jmb.2007.09.006  0.485
2007 Guan L, Mirza O, Verner G, Iwata S, Kaback HR. Structural determination of wild-type lactose permease. Proceedings of the National Academy of Sciences of the United States of America. 104: 15294-8. PMID 17881559 DOI: 10.1073/Pnas.0707688104  0.715
2007 Guan L, Kaback HR. Site-directed alkylation of cysteine to test solvent accessibility of membrane proteins. Nature Protocols. 2: 2012-7. PMID 17703213 DOI: 10.1038/Nprot.2007.275  0.687
2007 Majumdar DS, Smirnova I, Kasho V, Nir E, Kong X, Weiss S, Kaback HR. Single-molecule FRET reveals sugar-induced conformational dynamics in LacY. Proceedings of the National Academy of Sciences of the United States of America. 104: 12640-5. PMID 17502603 DOI: 10.1073/Pnas.0700969104  0.726
2007 Shimohata N, Nagamori S, Akiyama Y, Kaback HR, Ito K. SecY alterations that impair membrane protein folding and generate a membrane stress. The Journal of Cell Biology. 176: 307-17. PMID 17242069 DOI: 10.1083/Jcb.200611121  0.788
2007 Kaback HR, Dunten R, Frillingos S, Venkatesan P, Kwaw I, Zhang W, Ermolova N. Site-directed alkylation and the alternating access model for LacY. Proceedings of the National Academy of Sciences of the United States of America. 104: 491-4. PMID 17172438 DOI: 10.1073/Pnas.0609968104  0.516
2006 Smirnova IN, Kasho VN, Kaback HR. Direct sugar binding to LacY measured by resonance energy transfer. Biochemistry. 45: 15279-87. PMID 17176050 DOI: 10.1021/Bi061632M  0.39
2006 Nie Y, Smirnova I, Kasho V, Kaback HR. Energetics of ligand-induced conformational flexibility in the lactose permease of Escherichia coli. The Journal of Biological Chemistry. 281: 35779-84. PMID 17003033 DOI: 10.1074/Jbc.M607232200  0.427
2006 Guan L, Kaback HR. Lessons from lactose permease. Annual Review of Biophysics and Biomolecular Structure. 35: 67-91. PMID 16689628 DOI: 10.1146/Annurev.Biophys.35.040405.102005  0.716
2006 Kasho VN, Smirnova IN, Kaback HR. Sequence alignment and homology threading reveals prokaryotic and eukaryotic proteins similar to lactose permease. Journal of Molecular Biology. 358: 1060-70. PMID 16574153 DOI: 10.1016/J.Jmb.2006.02.049  0.509
2006 Vadyvaloo V, Smirnova IN, Kasho VN, Kaback HR. Conservation of residues involved in sugar/H(+) symport by the sucrose permease of Escherichia coli relative to lactose permease. Journal of Molecular Biology. 358: 1051-9. PMID 16574149 DOI: 10.1016/J.Jmb.2006.02.050  0.482
2006 Ermolova N, Madhvani RV, Kaback HR. Site-directed alkylation of cysteine replacements in the lactose permease of Escherichia coli: helices I, III, VI, and XI. Biochemistry. 45: 4182-9. PMID 16566592 DOI: 10.1021/Bi052631H  0.527
2006 Mirza O, Guan L, Verner G, Iwata S, Kaback HR. Structural evidence for induced fit and a mechanism for sugar/H+ symport in LacY. The Embo Journal. 25: 1177-83. PMID 16525509 DOI: 10.1038/Sj.Emboj.7601028  0.67
2006 Guan L, Smirnova IN, Verner G, Nagamori S, Nagamoni S, Kaback HR. Manipulating phospholipids for crystallization of a membrane transport protein. Proceedings of the National Academy of Sciences of the United States of America. 103: 1723-6. PMID 16446422 DOI: 10.1073/Pnas.0510922103  0.791
2006 Guan L, Smirnova IN, Verner G, Nagamori S, Kaback HR. Correction for Guan et al., Manipulating phospholipids for crystallization of a membrane transport protein Proceedings of the National Academy of Sciences of the United States of America. 103: 6073-6073. DOI: 10.1073/Pnas.0601039103  0.651
2005 Kaback HR. Structure and mechanism of the lactose permease. Comptes Rendus Biologies. 328: 557-67. PMID 15950162 DOI: 10.1016/J.Crvi.2005.03.008  0.496
2005 Ermolova NV, Smirnova IN, Kasho VN, Kaback HR. Interhelical packing modulates conformational flexibility in the lactose permease of Escherichia coli. Biochemistry. 44: 7669-77. PMID 15909981 DOI: 10.1021/Bi0502801  0.542
2005 van Bloois E, Nagamori S, Koningstein G, Ullers RS, Preuss M, Oudega B, Harms N, Kaback HR, Herrmann JM, Luirink J. The Sec-independent function of Escherichia coli YidC is evolutionary-conserved and essential. The Journal of Biological Chemistry. 280: 12996-3003. PMID 15671040 DOI: 10.1074/Jbc.M414094200  0.787
2005 Sun J, Savva CG, Deaton J, Kaback HR, Svrakic M, Young R, Holzenburg A. Asymmetric binding of membrane proteins to GroEL. Archives of Biochemistry and Biophysics. 434: 352-7. PMID 15639236 DOI: 10.1016/J.Abb.2004.11.021  0.467
2005 Weinglass AB, Soskine M, Vazquez-Ibar JL, Whitelegge JP, Faull KF, Kaback HR, Schuldiner S. Exploring the role of a unique carboxyl residue in EmrE by mass spectrometry. The Journal of Biological Chemistry. 280: 7487-92. PMID 15623511 DOI: 10.1074/Jbc.M413555200  0.456
2004 Abramson J, Iwata S, Kaback HR. Lactose permease as a paradigm for membrane transport proteins (Review). Molecular Membrane Biology. 21: 227-36. PMID 15371012 DOI: 10.1080/09687680410001716862  0.427
2004 Vázquez-Ibar JL, Guan L, Weinglass AB, Verner G, Gordillo R, Kaback HR. Sugar recognition by the lactose permease of Escherichia coli. The Journal of Biological Chemistry. 279: 49214-21. PMID 15364943 DOI: 10.1074/jbc.M407408200  0.655
2004 Abramson J, Kaback HR, Iwata S. Structural comparison of lactose permease and the glycerol-3-phosphate antiporter: members of the major facilitator superfamily. Current Opinion in Structural Biology. 14: 413-9. PMID 15313234 DOI: 10.1016/J.Sbi.2004.07.005  0.354
2004 Guan L, Kaback HR. Binding affinity of lactose permease is not altered by the H+ electrochemical gradient. Proceedings of the National Academy of Sciences of the United States of America. 101: 12148-52. PMID 15304639 DOI: 10.1073/Pnas.0404936101  0.693
2004 Weinglass A, Whitelegge JP, Faull KF, Kaback HR. Monitoring conformational rearrangements in the substrate-binding site of a membrane transport protein by mass spectrometry. The Journal of Biological Chemistry. 279: 41858-65. PMID 15272008 DOI: 10.1074/Jbc.M407555200  0.497
2004 Vardy E, Arkin IT, Gottschalk KE, Kaback HR, Schuldiner S. Structural conservation in the major facilitator superfamily as revealed by comparative modeling. Protein Science : a Publication of the Protein Society. 13: 1832-40. PMID 15215526 DOI: 10.1110/Ps.04657704  0.426
2004 Nagamori S, Smirnova IN, Kaback HR. Role of YidC in folding of polytopic membrane proteins. The Journal of Cell Biology. 165: 53-62. PMID 15067017 DOI: 10.1083/Jcb.200402067  0.799
2004 Sun J, Savva CG, Deaton J, Kaback HR, Svrakic M, Young RF, Holzenburg A. Visualization of membrane proteins in GroEL Microscopy and Microanalysis. 10: 232-233. DOI: 10.1017/S1431927604881297  0.352
2004 Iwata S, Kaback HR. Membranes: A new era in membrane protein studies Current Opinion in Structural Biology. 14: 387-389. DOI: 10.1016/J.Sbi.2004.07.009  0.392
2003 Abramson J, Smirnova I, Kasho V, Verner G, Iwata S, Kaback HR. The lactose permease of Escherichia coli: overall structure, the sugar-binding site and the alternating access model for transport. Febs Letters. 555: 96-101. PMID 14630326 DOI: 10.1016/S0014-5793(03)01087-1  0.558
2003 Vázquez-Ibar JL, Guan L, Svrakic M, Kaback HR. Exploiting luminescence spectroscopy to elucidate the interaction between sugar and a tryptophan residue in the lactose permease of Escherichia coli. Proceedings of the National Academy of Sciences of the United States of America. 100: 12706-11. PMID 14566061 DOI: 10.1073/Pnas.1835645100  0.652
2003 Ermolova N, Guan L, Kaback HR. Intermolecular thiol cross-linking via loops in the lactose permease of Escherichia coli. Proceedings of the National Academy of Sciences of the United States of America. 100: 10187-92. PMID 12934015 DOI: 10.1073/Pnas.1434239100  0.702
2003 Abramson J, Smirnova I, Kasho V, Verner G, Kaback HR, Iwata S. Structure and mechanism of the lactose permease of Escherichia coli. Science (New York, N.Y.). 301: 610-5. PMID 12893935 DOI: 10.1126/Science.1088196  0.534
2003 Sondej M, Vázquez-Ibar JL, Farshidi A, Peterkofsky A, Kaback HR. Characterization of a lactose permease mutant that binds IIAGlc in the absence of ligand. Biochemistry. 42: 9153-9. PMID 12885249 DOI: 10.1021/Bi034406A  0.489
2003 Zhang W, Hu Y, Kaback HR. Site-directed sulfhydryl labeling of helix IX in the lactose permease of Escherichia coli. Biochemistry. 42: 4904-8. PMID 12718531 DOI: 10.1021/Bi034078E  0.502
2003 Weinglass AB, Whitelegge JP, Hu Y, Verner GE, Faull KF, Kaback HR. Elucidation of substrate binding interactions in a membrane transport protein by mass spectrometry. The Embo Journal. 22: 1467-77. PMID 12660154 DOI: 10.1093/Emboj/Cdg145  0.438
2003 Smirnova IN, Kaback HR. A mutation in the lactose permease of Escherichia coli that decreases conformational flexibility and increases protein stability. Biochemistry. 42: 3025-31. PMID 12627968 DOI: 10.1021/Bi027329C  0.439
2003 Nagamori S, Vázquez-Ibar JL, Weinglass AB, Kaback HR. In vitro synthesis of lactose permease to probe the mechanism of membrane insertion and folding. The Journal of Biological Chemistry. 278: 14820-6. PMID 12590141 DOI: 10.1074/jbc.M300332200  0.786
2003 Guan L, Hu Y, Kaback HR. Aromatic stacking in the sugar binding site of the lactose permease. Biochemistry. 42: 1377-82. PMID 12578349 DOI: 10.1021/Bi027152M  0.7
2003 Guan L, Sahin-Tóth M, Kálai T, Hideg K, Kaback HR. Probing the mechanism of a membrane transport protein with affinity inactivators. The Journal of Biological Chemistry. 278: 10641-8. PMID 12471022 DOI: 10.1074/Jbc.M211355200  0.677
2002 Sorgen PL, Hu Y, Guan L, Kaback HR, Girvin ME. An approach to membrane protein structure without crystals. Proceedings of the National Academy of Sciences of the United States of America. 99: 14037-40. PMID 12391320 DOI: 10.1073/Pnas.182552199  0.693
2002 le Coutre J, Turk E, Kaback HR, Wright EM. Ligand-induced differences in secondary structure of the Vibrio parahaemolyticus Na+/galactose cotransporter. Biochemistry. 41: 8082-6. PMID 12069600 DOI: 10.1021/Bi025692D  0.423
2002 Guan L, Sahin-Toth M, Kaback HR. Changing the lactose permease of Escherichia coli into a galactose-specific symporter. Proceedings of the National Academy of Sciences of the United States of America. 99: 6613-8. PMID 12011425 DOI: 10.1073/Pnas.102178299  0.656
2002 Sondej M, Weinglass AB, Peterkofsky A, Kaback HR. Binding of enzyme IIAGlc, a component of the phosphoenolpyruvate:sugar phosphotransferase system, to the Escherichia coli lactose permease. Biochemistry. 41: 5556-65. PMID 11969416 DOI: 10.1021/Bi011990J  0.483
2002 Guan L, Murphy FD, Kaback HR. Surface-exposed positions in the transmembrane helices of the lactose permease of Escherichia coli determined by intermolecular thiol cross-linking. Proceedings of the National Academy of Sciences of the United States of America. 99: 3475-80. PMID 11904412 DOI: 10.1073/Pnas.052703699  0.66
2002 Vázquez-Ibar JL, Weinglass AB, Kaback HR. Engineering a terbium-binding site into an integral membrane protein for luminescence energy transfer. Proceedings of the National Academy of Sciences of the United States of America. 99: 3487-92. PMID 11891311 DOI: 10.1073/Pnas.052703599  0.43
2002 Weinglass AB, Sondej M, Kaback HR. Manipulating conformational equilibria in the lactose permease of Escherichia coli. Journal of Molecular Biology. 315: 561-71. PMID 11812130 DOI: 10.1006/Jmbi.2001.5289  0.528
2002 Zhang W, Guan L, Kaback HR. Helices VII and X in the lactose permease of Escherichia coli: proximity and ligand-induced distance changes. Journal of Molecular Biology. 315: 53-62. PMID 11771965 DOI: 10.1006/Jmbi.2001.5206  0.688
2002 Weinglass AB, Whitelegge JP, Hu Y, Faull KF, Kaback HR. Exploiting mass spectrometry for mechanistic studies of an integral membrane protein Proceedings 50th Asms Conference On Mass Spectrometry and Allied Topics. 105-106.  0.315
2001 Guan L, Weinglass AB, Kaback HR. Helix packing in the lactose permease of Escherichia coli: localization of helix VI. Journal of Molecular Biology. 312: 69-77. PMID 11545586 DOI: 10.1006/Jmbi.2001.4933  0.648
2001 Kwaw I, Zen KC, Hu Y, Kaback HR. Site-directed sulfhydryl labeling of the lactose permease of Escherichia coli: helices IV and V that contain the major determinants for substrate binding. Biochemistry. 40: 10491-9. PMID 11523990 DOI: 10.1021/Bi010866X  0.532
2001 Kaback HR, Sahin-Tóth M, Weinglass AB. The kamikaze approach to membrane transport. Nature Reviews. Molecular Cell Biology. 2: 610-20. PMID 11483994 DOI: 10.1038/35085077  0.455
2001 Sahin-Toth M, Kaback HR. Arg-302 facilitates deprotonation of Glu-325 in the transport mechanism of the lactose permease from Escherichiacoli. Proceedings of the National Academy of Sciences of the United States of America. 98: 6068-73. PMID 11353849 DOI: 10.1073/Pnas.111139698  0.51
2001 Wolin CD, Kaback HR. Functional estimation of loop-helix boundaries in the lactose permease of Escherichia coli by single amino acid deletion analysis. Biochemistry. 40: 1996-2003. PMID 11329266 DOI: 10.1021/bi0025767  0.802
2001 Weinglass AB, Smirnova IN, Kaback HR. Engineering conformational flexibility in the lactose permease of Escherichia coli: Use of glycine-scanning mutagenesis to rescue mutant Glu325→Asp Biochemistry. 40: 769-776. PMID 11170394 DOI: 10.1021/Bi002171M  0.533
2000 Zhang W, Kaback HR. Effect of the lipid phase transition on the lactose permease from Escherichia coli Biochemistry. 39: 14538-14542. PMID 11087408 DOI: 10.1021/bi001947g  0.354
2000 Sahin-Tóth M, Karlin A, Kaback HR. Unraveling the mechanism of the lactose permease of Escherichia coli. Proceedings of the National Academy of Sciences of the United States of America. 97: 10729-32. PMID 10984523 DOI: 10.1073/Pnas.200351797  0.46
2000 Venkatesan P, Hu Y, Kaback HR. Site-directed sulfhydryl labeling of the lactose permease of Escherichia coli: Helix X Biochemistry. 39: 10656-10661. PMID 10978149 DOI: 10.1021/bi0004403  0.421
2000 Venkatesan P, Liu Z, Hu Y, Kaback HR. Site-directed sulfhydryl labeling of the lactose permease of Escherichia coli: N-ethylmaleimide-sensitive face of helix II Biochemistry. 39: 10649-10655. PMID 10978148 DOI: 10.1021/bi0004394  0.395
2000 Venkatesan P, Kwaw I, Hu Y, Kaback HR. Site-directed sulfhydryl labeling of the lactose permease of Escherichia coli: Helix VII Biochemistry. 39: 10641-10648. PMID 10978147 DOI: 10.1021/bi000438b  0.42
2000 Weinglass AB, Kaback HR. The central cytoplasmic loop of the major facilitator superfamily of transport proteins governs efficient membrane insertion Proceedings of the National Academy of Sciences of the United States of America. 97: 8938-8943. PMID 10880570 DOI: 10.1073/Pnas.140224497  0.507
2000 Heymann JB, Pfeiffer M, Hildebrandt V, Kaback HR, Fotiadis D, Groot B, Engel A, Oesterhelt D, Müller DJ. Conformations of the rhodopsin third cytoplasmic loop grafted onto bacteriorhodopsin. Structure (London, England : 1993). 8: 643-53. PMID 10873864 DOI: 10.1016/S0969-2126(00)00151-9  0.422
2000 Sahin-Tóth M, Kaback HR. Functional conservation in the putative substrate binding site of the sucrose permease from Escherichia coli Biochemistry. 39: 6170-6175. PMID 10821691 DOI: 10.1021/bi000125g  0.419
2000 Sahin-Tóth M, Frillingos S, Lawrence MC, Kaback HR. The sucrose permease of Escherichia coli: functional significance of cysteine residues and properties of a cysteine-less transporter. Biochemistry. 39: 6164-9. PMID 10821690 DOI: 10.1021/Bi000124O  0.539
2000 Wolin CD, Kaback HR. Thiol cross-linking of transmembrane domains IV and V in the lactose permease of Escherichia coli. Biochemistry. 39: 6130-5. PMID 10821686 DOI: 10.1021/bi0001269  0.811
2000 Kwaw I, Jianzhong S, Kaback HR. Thiol cross-linking of cytoplasmic loops in the lactose permease of Escherichia coli Biochemistry. 39: 3134-3140. PMID 10715135 DOI: 10.1021/bi992509g  0.3
2000 Kaback HR. The Lactose Permease of Escherichia coli: The Kamikaze Approach to Membrane Protein Structure and Function Biochemical Society Transactions. 28: A143-A143. DOI: 10.1042/bst028a143b  0.318
1999 Zhao M, Zen KC, Hernandez-Borrell J, Altenbach C, Hubbell WL, Kaback HR. Nitroxide scanning electron paramagnetic resonance of helices IV and V and the intervening loop in the lactose permease of Escherichia coli. Biochemistry. 38: 15970-7. PMID 10625464 DOI: 10.1021/Bi991754X  0.388
1999 Wang Q, Kaback HR. Location of helix III in the lactose permease of Escherichia coli as determined by site-directed thiol cross-linking Biochemistry. 38: 16777-16782. PMID 10606509 DOI: 10.1021/bi991853a  0.316
1999 Weinglass AB, Kaback HR. Conformational flexibility at the substrate binding site in the lactose permease of Escherichia coli Proceedings of the National Academy of Sciences of the United States of America. 96: 11178-11182. PMID 10500150 DOI: 10.1073/Pnas.96.20.11178  0.515
1999 Wang Q, Kaback HR. Proximity relationships between helices I and XI or XII in the lactose permease of Escherichia coli determined by site-directed thiol cross-linking Journal of Molecular Biology. 291: 683-692. PMID 10448046 DOI: 10.1006/Jmbi.1999.2948  0.483
1999 Wolin CD, Kaback HR. Estimating loop-helix interfaces in a polytopic membrane protein by deletion analysis. Biochemistry. 38: 8590-7. PMID 10387107 DOI: 10.1021/bi990650j  0.823
1999 Zhao M, Zen KC, Hubbell WL, Kaback HR. Proximity between Glu126 and Arg144 in the lactose permease of Escherichia coli. Biochemistry. 38: 7407-12. PMID 10360937 DOI: 10.1021/Bi9906524  0.38
1999 Zhuang J, Privé GG, Werner GE, Ringler P, Kaback HR, Engel A. Two-dimensional crystallization of Escherichia coli lactose permease Journal of Structural Biology. 125: 63-75. PMID 10196117 DOI: 10.1006/Jsbi.1998.4059  0.591
1999 Sondej M, Sun J, Seok YJ, Kaback HR, Peterkofsky A. Deduction of consensus binding sequences on proteins that bind IIa(Glc) of the phosphoenolpyruvate:sugar phosphotransferase system by cysteine scanning mutagenesis of Escherichia coli lactose permease Proceedings of the National Academy of Sciences of the United States of America. 96: 3525-3530. PMID 10097069 DOI: 10.1073/pnas.96.7.3525  0.366
1999 Wang Q, Kaback HR. Helix packing in the lactose permease of Escherichia coli determined by site-directed thiol cross-linking: Helix I is close to helices V and XI Biochemistry. 38: 3120-3126. PMID 10074366 DOI: 10.1021/bi982507g  0.371
1999 Wu J, Hardy D, Kaback HR. Tertiary contacts of helix V in the lactose permease determined by site- directed chemical cross-linking in situ Biochemistry. 38: 2320-2325. PMID 10029525 DOI: 10.1021/bi982288z  0.339
1999 Sahin-Tóth M, le Coutre J, Kharabi D, le Maire G, Lee JC, Kaback HR. Characterization of Glu126 and Arg144, two residues that are indispensable for substrate binding in the lactose permease of Escherichia coli. Biochemistry. 38: 813-9. PMID 9888822 DOI: 10.1021/Bi982200H  0.385
1999 Kaback HR, Wu J. What to do while awaiting crystals of a membrane transport protein and thereafter Accounts of Chemical Research. 32: 805-813. DOI: 10.1021/ar970256i  0.319
1999 Zhao M, Zen KC, Hubbell WL, Kaback HR. Proximity between Glu126 and Arg144 in the lactose permease of Escherichia coli Biochemistry. 38.  0.376
1998 Wu J, Hardy D, Kaback HR. Tilting of helix I and ligand-induced changes in the lactose permease determined by site-directed chemical cross-linking in situ. Biochemistry. 37: 15785-90. PMID 9843383 DOI: 10.1021/bi981501o  0.311
1998 Pouny Y, Weitzman C, Kaback HR. In vitro biotinylation provides quantitative recovery of highly purified active lactose permease in a single step. Biochemistry. 37: 15713-9. PMID 9843376 DOI: 10.1021/bi981519z  0.338
1998 Frillingos S, Sahin-Tóth M, Wu J, Kaback HR. Cys-scanning mutagenesis: A novel approach to structure-function relationships in polytopic membrane proteins Faseb Journal. 12: 1281-1299. PMID 9761772 DOI: 10.1096/Fasebj.12.13.1281  0.548
1998 Wu J, Hardy D, Kaback HR. Transmembrane helix tilting and ligand-induced conformational changes in the lactose permease determined by site-directed chemical crosslinking in situ Journal of Molecular Biology. 282: 959-967. PMID 9753547 DOI: 10.1006/jmbi.1998.2065  0.329
1998 Venkatesan P, Kaback HR. The substrate-binding site in the lactose permease of Escherichia coli Proceedings of the National Academy of Sciences of the United States of America. 95: 9802-9807. PMID 9707556 DOI: 10.1073/Pnas.95.17.9802  0.479
1998 Voss J, Sun J, Venkatesan P, Kaback HR. Sulfhydryl oxidation of mutants with cysteine in place of acidic residues in the lactose permease Biochemistry. 37: 8191-8196. PMID 9609715 DOI: 10.1021/Bi9802667  0.308
1998 le Coutre J, Kaback HR, Patel CK, Heginbotham L, Miller C. Fourier transform infrared spectroscopy reveals a rigid alpha-helical assembly for the tetrameric Streptomyces lividans K+ channel. Proceedings of the National Academy of Sciences of the United States of America. 95: 6114-7. PMID 9600926 DOI: 10.1073/Pnas.95.11.6114  0.376
1998 He MM, Kaback HR. In vitro folding of a membrane protein: Effect of denaturation and renaturation on substrate binding by the lactose permease of Escherichia coli Molecular Membrane Biology. 15: 15-20. PMID 9595550  0.336
1998 Voss J, Hubbell WL, Kaback HR. Helix packing in the lactose permease determined by metal-nitroxide interaction Biochemistry. 37: 211-216. PMID 9425041 DOI: 10.1021/bi972152l  0.305
1997 Kaback HR, Wu J. From membrane to molecule to the third amino acid from the left with a membrane transport protein Quarterly Reviews of Biophysics. 30: 333-364. PMID 9634651 DOI: 10.1017/S0033583597003387  0.396
1997 Frillingos S, Gonzalez A, Kaback HR. Cysteine-scanning mutagenesis of helix IV and the adjoining loops in the lactose permease of Escherichia coli: Glu126 and Arg144 are essential Biochemistry. 36: 14284-14290. PMID 9400367 DOI: 10.1021/bi972314d  0.329
1997 Voss J, Hubbell WL, Hernandez-Borrell J, Kaback HR. Site-directed spin-labeling of transmembrane domain VII and the 4B1 antibody epitope in the lactose permease of Escherichia coli Biochemistry. 36: 15055-15061. PMID 9398232 DOI: 10.1021/bi971726j  0.305
1997 Seok YJ, Sun J, Kaback HR, Peterkofsky A. Topology of allosteric regulation of lactose permease Proceedings of the National Academy of Sciences of the United States of America. 94: 13515-13519. PMID 9391057 DOI: 10.1073/pnas.94.25.13515  0.381
1997 Wang Q, Matsushita K, De Foresta B, Le Maire M, Kaback HR. Ligand-induced movement of helix X in the lactose permease from Escherichia coli: A fluorescence quenching study Biochemistry. 36: 14120-14127. PMID 9369484 DOI: 10.1021/bi9716433  0.328
1997 Braun P, Persson B, Kaback HR, Von Heijne G. Alanine insertion scanning mutagenesis of lactose permease transmembrane helices Journal of Biological Chemistry. 272: 29566-29571. PMID 9368019 DOI: 10.1074/jbc.272.47.29566  0.441
1997 He MM, Kaback HR. Interaction between residues Glu269 (helix VIII) and His322 (helix X) of the lactose permease of Escherichia coli is essential for substrate binding Biochemistry. 36: 13688-13692. PMID 9354639 DOI: 10.1021/bi9715324  0.388
1997 He MM, Voss J, Hubbell WL, Kaback HR. Arginine 302 (helix IX) in the lactose permease of Escherichia coli is in close proximity to glutamate 269 (helix VIII) as well as glutamate 325 (helix X) Biochemistry. 36: 13682-13687. PMID 9354638 DOI: 10.1021/Bi971531B  0.302
1997 Sun J, Kaback HR. Proximity of periplasmic loops in the lactose permease of Escherichia coli determined by site-directed cross-linking Biochemistry. 36: 11959-11965. PMID 9305990 DOI: 10.1021/bi971172k  0.36
1997 le Coutre J, Narasimhan LR, Patel CK, Kaback HR. The lipid bilayer determines helical tilt angle and function in lactose permease of Escherichia coli. Proceedings of the National Academy of Sciences of the United States of America. 94: 10167-71. PMID 9294181 DOI: 10.1073/Pnas.94.19.10167  0.381
1997 Kaback HR, Voss J, Wu J. Helix packing in polytopic membrane proteins: The lactose permease of Escherichia coli Current Opinion in Structural Biology. 7: 537-542. PMID 9266176 DOI: 10.1016/S0959-440X(97)80119-4  0.431
1997 Wu J, Kaback HR. Helix proximity and ligand-induced conformational changes in the lactose permease of Escherichia coli determined by site-directed chemical crosslinking Journal of Molecular Biology. 270: 285-293. PMID 9236129 DOI: 10.1006/Jmbi.1997.1099  0.35
1997 Sun J, Frillingos S, Kaback HR. Binding of monoclonal antibody 4B1 to homologs of the lactose permease of Escherichia coli Protein Science. 6: 1503-1510. PMID 9232651  0.328
1997 Frillingos S, Wu J, Venkatesan P, Kaback HR. Binding of ligand or monoclonal antibody 4B1 induces discrete structural changes in the lactose permease of Escherichia coli Biochemistry. 36: 6408-6414. PMID 9174357 DOI: 10.1021/bi970233b  0.332
1997 Kaback HR. A molecular mechanism for energy coupling in a membrane transport protein, the lactose permease of Escherichia coli Proceedings of the National Academy of Sciences of the United States of America. 94: 5539-5543. PMID 9159108 DOI: 10.1073/Pnas.94.11.5539  0.537
1997 Frillingos S, Kaback HR. The role of helix VII in the lactose permease of Escherichia coli: II. Site-directed sulfhydryl modification Protein Science. 6: 438-443. PMID 9041647  0.418
1997 Frillingos S, Ujwal ML, Sun J, Kaback HR. The role of helix VIII in the lactose permease of Escherichia coli: I. Cys-scanning mutagenesis Protein Science. 6: 431-437. PMID 9041646  0.405
1997 Merickel A, Kaback HR, Edwards RH. Charged residues in transmembrane domains II and XI of a vesicular monoamine transporter form a charge pair that promotes high affinity substrate recognition. The Journal of Biological Chemistry. 272: 5403-8. PMID 9038139 DOI: 10.1074/jbc.272.9.5403  0.396
1997 Sun J, Li J, Carrasco N, Kaback HR. The last two cytoplasmic loops in the lactose permease of Escherichia coli comprise a discontinuous epitope for a monoclonal antibody Biochemistry. 36: 274-280. PMID 8993344 DOI: 10.1021/bi962292f  0.326
1997 Frillingos S, Sun J, Gonzalez A, Kaback HR. Cysteine-scanning mutagenesis of helix II and flanking hydrophilic domains in the lactose permease of Escherichia coli Biochemistry. 36: 269-273. PMID 8993343 DOI: 10.1021/bi9618629  0.379
1996 Wu J, Kaback HR. A general method for determining helix packing in membrane proteins in situ: Helices I and II are close to helix VII in the lactose permease of Escherichia coli Proceedings of the National Academy of Sciences of the United States of America. 93: 14498-14502. PMID 8962080 DOI: 10.1073/pnas.93.25.14498  0.389
1996 Frillingos S, Kaback HR. Chemical rescue of Asp237-->Ala and Lys358-->Ala mutants in the lactose permease of Escherichia coli. Biochemistry. 35: 13363-7. PMID 8873603 DOI: 10.1021/bi961453c  0.383
1996 He MM, Sun J, Kaback HR. Cysteine-scanning mutagenesis of transmembrane domain XII and the flanking periplasmic loop in the lactose permease of EScherichia coli. Biochemistry. 35: 12909-14. PMID 8841135 DOI: 10.1021/bi960876b  0.366
1996 Privé GG, Kaback HR. Engineering the lac permease for purification and crystallization Journal of Bioenergetics and Biomembranes. 28: 29-34. PMID 8786234  0.626
1996 Frillingos S, Kaback HR. Monoclonal antibody 4B1 alters the pKa of a carboxylic acid at position 325 (helix X) of the lactose permease of Escherichia coli. Biochemistry. 35: 10166-71. PMID 8756481 DOI: 10.1021/bi960995r  0.305
1996 Pourcher T, Bibi E, Kaback HR, Leblanc G. Membrane topology of the melibiose permease of Escherichia coli studied by melB-phoA fusion analysis Biochemistry. 35: 4161-4168. PMID 8672452 DOI: 10.1021/bi9527496  0.684
1996 Frillingos S, Kaback HR. Probing the conformation of the lactose permease of Escherichia coli by in situ site-directed sulfhydryl modification Biochemistry. 35: 3950-3956. PMID 8672426 DOI: 10.1021/bi952601m  0.404
1996 Bogdanov M, Sun J, Kaback HR, Dowhan W. A phospholipid acts as a chaperone in assembly of a membrane transport protein Journal of Biological Chemistry. 271: 11615-11618. PMID 8662750 DOI: 10.1074/Jbc.271.20.11615  0.42
1996 Frillingos S, Kaback HR. Cysteine-scanning mutagenesis of helix VI and the flanking hydrophilic domains in the lactose permease of Escherichia coli Biochemistry. 35: 5333-5338. PMID 8611521 DOI: 10.1021/bi953068d  0.381
1996 Wu J, Sun J, Kaback HR. Purification and functional characterization of the C-terminal half of the lactose permease of Escherichia coli Biochemistry. 35: 5213-5219. PMID 8611506 DOI: 10.1021/bi960064f  0.322
1996 Sun J, Wu J, Carrasco N, Kaback HR. Identification of the epitope for monoclonal antibody 4B1 which uncouples lactose and proton translocation in the lactose permease of Escherichia coli Biochemistry. 35: 990-998. PMID 8547282 DOI: 10.1021/Bi952166W  0.477
1995 Voss J, Hubbell WL, Kaback HR. Distance determination in proteins using designed metal ion binding sites and site-directed spin labeling: Application to the lactose permease of Escherichia coli Proceedings of the National Academy of Sciences of the United States of America. 92: 12300-12303. PMID 8618889 DOI: 10.1073/Pnas.92.26.12300  0.355
1995 Weitzman C, Consler TG, Kaback HR. Fluorescence of native single-Trp mutants in the lactose permease from Escherichia coli: Structural properties and evidence for a substrate-induced conformational change Protein Science. 4: 2310-2318. PMID 8563627 DOI: 10.1002/Pro.5560041108  0.422
1995 Zen KH, Consler TG, Kaback HR. Insertion of the polytopic membrane protein lactose permease occurs by multiple mechanisms Biochemistry. 34: 3430-3437. PMID 7880837  0.384
1995 Sahin-Tóth M, Dunten RL, Kaback HR. Design of a membrane protein for site-specific proteolysis: properties of engineered factor Xa protease sites in the lactose permease of Escherichia coli. Biochemistry. 34: 1107-12. PMID 7827058 DOI: 10.1021/bi00004a001  0.417
1995 Jung K, Jung H, Colacurcio P, Kaback HR. Role of glycine residues in the structure and function of lactose permease, an Escherichia coli membrane transport protein. Biochemistry. 34: 1030-9. PMID 7827019 DOI: 10.1021/bi00003a038  0.37
1995 Jung K, Voss J, He M, Hubbell WL, Kaback HR. Engineering a metal binding site within a polytopic membrane protein, the lactose permease of Escherichia coli Biochemistry®. 34: 6272-6277. PMID 7756253  0.419
1995 Weitzman C, Kaback HR. Cysteine scanning mutagenesis of helix V in the lactose permease of Escherichia coli Biochemistry. 34: 9374-9379. PMID 7626607 DOI: 10.1021/bi00029a013  0.361
1995 Frillingos S, Sahin-Tóth M, Lengeler JW, Kaback HR. Helix packing in the sucrose permease of Escherichia coli: properties of engineered charge pairs between helices VII and XI. Biochemistry. 34: 9368-73. PMID 7626606 DOI: 10.1021/bi00029a012  0.362
1995 Wu J, Frillingos S, Kaback HR. Dynamics of lactose permease of Escherichia coli determined by site-directed chemical labeling and fluorescence spectroscopy. Biochemistry. 34: 8257-63. PMID 7599118 DOI: 10.1021/bi00026a007  0.346
1995 Ujwal ML, Jung H, Bibi E, Manoil C, Altenbach C, Hubbell WL, Kaback HR. Membrane topology of helices VII and XI in the lactose permease of Escherichia coli studied by lacY-phoA fusion analysis and site-directed spectroscopy Biochemistry. 34: 14909-14917. PMID 7578103  0.709
1995 Wu J, Perrin DM, Sigman DS, Kaback HR. Helix packing of lactose permease in Escherichia coli studied by site-directed chemical cleavage Proceedings of the National Academy of Sciences of the United States of America. 92: 9186-9190. PMID 7568098  0.31
1995 Kaback HR, Jung K, Jung H, Wu J, Privé GG, Zen K. Helix packing in the C-terminal half of lactose permease Advances in Cellular and Molecular Biology of Membranes and Organelles. 4: 129-144. DOI: 10.1016/S1874-5172(06)80010-6  0.731
1994 Privé GG, Verner GE, Weitzman C, Zen KH, Eisenberg D, Kaback HR. Fusion proteins as tools for crystallization: the lactose permease from Escherichia coli. Acta Crystallographica. Section D, Biological Crystallography. 50: 375-9. PMID 15299388 DOI: 10.1107/S0907444993014301  0.679
1994 Sahin-Tóth M, Lawrence MC, Kaback HR. Properties of permease dimer, a fusion protein containing two lactose permease molecules from Escherichia coli. Proceedings of the National Academy of Sciences of the United States of America. 91: 5421-5. PMID 8202501 DOI: 10.1073/Pnas.91.12.5421  0.357
1994 Jung K, Jung H, Kaback HR. Dynamics of lactose permease of Escherichia coli determined by site-directed fluorescence labeling. Biochemistry. 33: 3980-5. PMID 8142402 DOI: 10.1021/bi00179a026  0.303
1994 Zen KH, McKenna E, Bibi E, Hardy D, Kaback HR. Expression of lactose permease in contiguous fragments as a probe for membrane-spanning domains Biochemistry. 33: 8198-8206. PMID 8031753 DOI: 10.1021/bi00193a005  0.685
1994 Sahin-Toth M, Persson B, Schwieger J, Cohan P, Kaback HR. Cysteine scanning mutagenesis of the N-terminal 32 amino acid residues in the lactose permease of Escherichia coli Protein Science. 3: 240-247. PMID 8003960 DOI: 10.1002/Pro.5560030208  0.517
1994 Jung H, Jung K, Kaback HR. A conformational change in the lactose permease of Escherichia coli is induced by ligand binding or membrane potential Protein Science. 3: 1052-1057. PMID 7920250 DOI: 10.1002/Pro.5560030707  0.519
1994 Wu J, Kaback HR. Cysteine 148 in the lactose permease of Escherichia coli is a component of a substrate binding site. 2. Site-directed fluorescence studies Biochemistry. 33: 12166-12171. PMID 7918438 DOI: 10.1021/bi00206a020  0.339
1994 Jung H, Jung K, Kaback HR. Cysteine 148 in the lactose permease of Escherichia coli is a component of a substrate binding site. 1. Site-directed mutagenesis studies Biochemistry. 33: 12160-12165. PMID 7918437 DOI: 10.1021/bi00206a019  0.36
1994 Ujwal ML, Sahin-Tóth M, Persson B, Kaback HR. Role of glutamate-269 in the lactose permease of escherichia coli Molecular Membrane Biology. 11: 9-16. PMID 7912610 DOI: 10.3109/09687689409161024  0.395
1994 Kaback HR, Frillingos S, Jung H, Jung K, Prive GG, Ujwal ML, Weitzman C, Wu Jianhua, Zen K. The lactose permease meets Frankenstein Journal of Experimental Biology. 196: 183-195. PMID 7823021  0.527
1994 Sahin-Toth M, Frillingos S, Bibi E, Gonzalez A, Kaback HR. The role of transmembrane domain III in the lactose permease of Escherichia coli Protein Science. 3: 2302-2310. PMID 7756986 DOI: 10.1002/Pro.5560031215  0.694
1994 Wu J, Frillingos S, Voss J, Kaback HR. Ligand-induced conformational changes in the lactose permease of Escherichia coli: Evidence for two binding sites Protein Science. 3: 2294-2301. PMID 7756985 DOI: 10.1002/Pro.5560031214  0.307
1994 Frillingos S, Sahin-Tóth M, Persson B, Kaback HR. Cysteine-scanning mutagenesis of putative helix VII in the lactose permease of Escherichia coli Biochemistry. 33: 8074-8081.  0.41
1993 Sahin-Tóth M, Dunten RL, Kaback HR. The lactose permease of Escherichia coli: a paradigm for membrane transport proteins. Society of General Physiologists Series. 48: 1-9. PMID 8503038  0.367
1993 Dunten RL, Sahin-Tóth M, Kaback HR. Role of the charge pair aspartic acid-237-lysine-358 in the lactose permease of Escherichia coli. Biochemistry. 32: 3139-45. PMID 8457574 DOI: 10.1021/bi00063a028  0.346
1993 Sahin-Tóth M, Kaback HR. Properties of interacting aspartic acid and lysine residues in the lactose permease of Escherichia coli. Biochemistry. 32: 10027-35. PMID 8399130 DOI: 10.1021/bi00089a019  0.327
1993 Consler TG, Persson BL, Jung H, Zen KH, Jung K, Privé GG, Verner GE, Kaback HR. Properties and purification of an active biotinylated lactose permease from Escherichia coli. Proceedings of the National Academy of Sciences of the United States of America. 90: 6934-8. PMID 8346199 DOI: 10.1073/Pnas.90.15.6934  0.704
1993 Sahin-Toth M, Kaback HR. Cysteine scanning mutagenesis of putative transmembrane helices IX and X in the lactose permease of Escherichia coli Protein Science. 2: 1024-1033. PMID 8318887 DOI: 10.1002/Pro.5560020615  0.511
1993 Dunten RL, Sahin-Toth M, Kaback HR. Cysteine scanning mutagenesis of putative helix XI in the lactose permease of Escherichia coli Biochemistry. 32: 12644-12650. PMID 8251482 DOI: 10.1021/bi00210a012  0.428
1993 Jung K, Jung H, Wu J, Privé GG, Kaback HR. Use of site-directed fluorescence labeling to study proximity relationships in the lactose permease of Escherichia coli. Biochemistry. 32: 12273-8. PMID 8241112 DOI: 10.1021/Bi00097A001  0.695
1993 Kaback HR, Jung K, Jung H, Wu J, Privé GG, Zen K. What's new with lactose permease. Journal of Bioenergetics and Biomembranes. 25: 627-36. PMID 8144491 DOI: 10.1007/Bf00770250  0.691
1993 Bibi E, Gros P, Kaback HR. Functional expression of mouse mdr1 in Escherichia coli Proceedings of the National Academy of Sciences of the United States of America. 90: 9209-9213. PMID 8105473 DOI: 10.1073/Pnas.90.19.9209  0.641
1993 McKenna E, Hardy D, Kaback HR. Insertional mutagenesis of hydrophilic domains in the lactose permease of Escherichia coli. Proceedings of the National Academy of Sciences of the United States of America. 89: 11954-8. PMID 1465425 DOI: 10.1073/pnas.89.24.11954  0.383
1992 Kaback HR. The lactose permease of Escherichia coli: a paradigm for membrane transport proteins. Biochimica Et Biophysica Acta. 1101: 210-3. PMID 1633187  0.367
1992 Pourcher T, Bassilana M, Sarkar HK, Kaback HR, Leblanc G. Melibiose permease of Escherichia coli: mutation of histidine-94 alters expression and stability rather than catalytic activity. Biochemistry. 31: 5225-31. PMID 1606146 DOI: 10.1021/bi00137a018  0.447
1992 Bibi E, Stearns SM, Kaback HR. The N-terminal 22 amino acid residues in the lactose permease of Escherichia coli are not obligatory for membrane insertion or transport activity Proceedings of the National Academy of Sciences of the United States of America. 89: 3180-3184. PMID 1565610 DOI: 10.1073/Pnas.89.8.3180  0.705
1992 McKenna E, Hardy D, Kaback HR. Evidence that the final turn of the last transmembrane helix in the lactose permease is required for folding. The Journal of Biological Chemistry. 267: 6471-4. PMID 1551862  0.389
1992 Bibi E, Kaback HR. Functional complementation of internal deletion mutants in the lactose permease of Escherichia coli Proceedings of the National Academy of Sciences of the United States of America. 89: 1524-1528. PMID 1542643 DOI: 10.1073/Pnas.89.5.1524  0.666
1992 Sahin-Toth M, Dunten RL, Gonzalez A, Kaback HR. Functional interactions between putative intramembrane charged residues in the lactose permease of Escherichia coli Proceedings of the National Academy of Sciences of the United States of America. 89: 10547-10551. PMID 1438245 DOI: 10.1073/Pnas.89.21.10547  0.351
1992 Persson B, Roepe PD, Patel L, Lee J, Kaback HR. Site-directed mutagenesis of lysine 319 in the lactose permease of Escherichia coli Biochemistry. 31: 8892-8897. PMID 1390676  0.396
1992 Gros P, Talbot F, Tang-Wai D, Bibi E, Kaback HR. Lipophilic cations: A group of model substrates for the multidrug- resistance transporter Biochemistry. 31: 1992-1998. PMID 1371401 DOI: 10.1021/bi00122a014  0.595
1992 Kaback HR. In and out and up and down with lac permease. International Review of Cytology. 137: 97-125. PMID 1330966 DOI: 10.1016/S0074-7696(08)62674-1  0.492
1992 Kaback HR. The lactose permease ofEscherichia coli: a paradigm for membrane transport proteins Biochimica Et Biophysica Acta (Bba) - Bioenergetics. 1101: 210-213. DOI: 10.1016/0005-2728(92)90227-S  0.511
1991 McKenna E, Hardy D, Pastore JC, Kaback HR. Sequential truncation of the lactose permease over a three-amino acid sequence near the carboxyl terminus leads to progressive loss of activity and stability Proceedings of the National Academy of Sciences of the United States of America. 88: 2969-2973. PMID 2014218 DOI: 10.1073/pnas.88.8.2969  0.336
1991 Consler TG, Tsolas O, Kaback HR. Role of proline residues in the structure and function of a membrane transport protein. Biochemistry. 30: 1291-8. PMID 1991110 DOI: 10.1021/bi00219a019  0.438
1991 Lolkema JS, Carrasco N, Kaback HR. Kinetic analysis of lactose exchange in proteoliposomes reconstituted with purified lac permease. Biochemistry. 30: 1284-90. PMID 1991109 DOI: 10.1021/Bi00219A018  0.429
1991 van Iwaarden PR, Pastore JC, Konings WN, Kaback HR. Construction of a functional lactose permease devoid of cysteine residues. Biochemistry. 30: 9595-600. PMID 1911745 DOI: 10.1021/bi00104a005  0.384
1991 van Iwaarden PR, Driessen AJ, Menick DR, Kaback HR, Konings WN. Characterization of purified, reconstituted site-directed cysteine mutants of the lactose permease of Escherichia coli. The Journal of Biological Chemistry. 266: 15688-92. PMID 1874727  0.405
1991 Bibi E, Verner G, Chang CY, Kaback HR. Organization and stability of a polytopic membrane protein: Deletion analysis of the lactose permease of Escherichia coli Proceedings of the National Academy of Sciences of the United States of America. 88: 7271-7275. PMID 1871132 DOI: 10.1073/Pnas.88.16.7271  0.69
1990 Santos E, Kaback HR. Monoclonal affinity purification of D-lactate dehydrogenase from Escherichia coli. Methods in Enzymology. 126: 370-7. PMID 3078444 DOI: 10.1016/S0076-6879(86)26037-1  0.359
1990 Menezes ME, Roepe PD, Kaback HR. Design of a membrane transport protein for fluorescence spectroscopy Proceedings of the National Academy of Sciences of the United States of America. 87: 1638-1642. PMID 2408040  0.348
1990 Pourcher T, Sarkar HK, Bassilana M, Kaback HR, Leblanc G. Histidine-94 is the only important histidine residue in the melibiose permease of Escherichia coli. Proceedings of the National Academy of Sciences of the United States of America. 87: 468-72. PMID 2404282 DOI: 10.1073/pnas.87.1.468  0.383
1990 Bibi E, Kaback HR. In vivo expression of the lacY gene in two segments leads to functional lac permease Proceedings of the National Academy of Sciences of the United States of America. 87: 4325-4329. PMID 2190220 DOI: 10.1073/Pnas.87.11.4325  0.642
1990 Roepe PD, Kaback HR. Isolation and functional reconstitution of soluble melibiose permease from Escherichia coli Biochemistry. 29: 2572-2577. PMID 2185831  0.357
1990 Roepe PD, Consler TG, Menezes ME, Kaback HR. The lac permease of Escherichia coli: site-directed mutagenesis studies on the mechanism of β-galactoside/H+ symport Research in Microbiology. 141: 290-308. PMID 2177909 DOI: 10.1016/0923-2508(90)90003-9  0.336
1990 Kaback HR. Lac permease of Escherichia coli: on the path of the proton. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 326: 425-36. PMID 1970647 DOI: 10.1098/rstb.1990.0022  0.425
1990 Pourcher T, Bassilana M, Sarkar HK, Kaback HR, Leblanc G. The melibiose/Na+ symporter of Escherichia coli: kinetic and molecular properties. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 326: 411-23. PMID 1970646 DOI: 10.1098/rstb.1990.0021  0.411
1989 Lolkema JS, Püttner IB, Kaback HR. Site-directed mutagenesis of Pro327 in the lac permease of Escherichia coli. Biochemistry. 27: 8307-10. PMID 3072017 DOI: 10.1021/Bi00422A003  0.404
1989 Roepe PD, Kaback HR. Characterization and functional reconstitution of a soluble form of the hydrophobic membrane protein lac permease from Escherichia coli Proceedings of the National Academy of Sciences of the United States of America. 86: 6087-6091. PMID 2668955  0.385
1989 Püttner IB, Sarkar HK, Padan E, Lolkema JS, Kaback HR. Characterization of site-directed mutants in the lac permease of Escherichia coli. 1. Replacement of histidine residues. Biochemistry. 28: 2525-33. PMID 2659072 DOI: 10.1021/Bi00432A027  0.457
1989 Roepe PD, Zbar RIS, Sarkar K, Kaback HR. A five-residue sequence near the carboxyl terminus of the polytopic membrane protein lac permease is required for stability within the membrane Proceedings of the National Academy of Sciences of the United States of America. 86: 3992-3996. PMID 2657733  0.435
1989 Lee JA, Püttner IB, Kaback HR. Effect of distance and orientation between arginine-302, histidine-322, and glutamate-325 on the activity of lac permease from Escherichia coli. Biochemistry. 28: 2540-4. PMID 2567182 DOI: 10.1021/Bi00432A029  0.428
1989 Carrasco N, Püttner IB, Antes LM, Lee JA, Larigan JD, Lolkema JS, Roepe PD, Kaback HR. Characterization of site-directed mutants in the lac permease of Escherichia coli. 2. Glutamate-325 replacements Biochemistry. 28: 2533-2539. PMID 2567181 DOI: 10.1021/Bi00432A028  0.462
1988 Püttner IB, Kaback HR. lac permease of Escherichia coli containing a single histidine residue is fully functional. Proceedings of the National Academy of Sciences of the United States of America. 85: 1467-71. PMID 3278314 DOI: 10.1073/pnas.85.5.1467  0.373
1988 Matsushita K, Ohnishi T, Kaback HR. NADH-ubiquinone oxidoreductases of the Escherichia coli aerobic respiratory chain. Biochemistry. 26: 7732-7. PMID 3122832 DOI: 10.1021/Bi00398A029  0.44
1987 Kaback HR. Use of site-directed mutagenesis to study the mechanism of a membrane transport protein. Biochemistry. 26: 2071-6. PMID 3304418 DOI: 10.1021/bi00382a001  0.358
1986 Viitanen PV, Menick DR, Sarkar HK, Trumble WR, Kaback HR. Site-directed mutagenesis of cysteine-148 in the lac permease of Escherichia coli: effect on transport, binding, and sulfhydryl inactivation. Biochemistry. 24: 7628-35. PMID 3912006 DOI: 10.1021/bi00347a020  0.368
1986 Püttner IB, Sarkar HK, Poonian MS, Kaback HR. lac permease of Escherichia coli: histidine-205 and histidine-322 play different roles in lactose/H+ symport. Biochemistry. 25: 4483-5. PMID 3533138 DOI: 10.1021/Bi00364A003  0.386
1986 Carrasco N, Herzlinger D, Danho W, Kaback HR. Preparation of monoclonal antibodies and site-directed polyclonal antibodies against the lac permease of Escherichia coli. Methods in Enzymology. 125: 453-67. PMID 3520230 DOI: 10.1016/S0076-6879(86)25035-1  0.406
1986 Sarkar HK, Viitanen PV, Padan E, Trumble WR, Poonian MS, McComas W, Kaback HR. Oligonucleotide-directed site-specific mutagenesis of the lac permease of Escherichia coli. Methods in Enzymology. 125: 214-30. PMID 3520222 DOI: 10.1016/S0076-6879(86)25019-3  0.419
1986 Sarkar HK, Menick DR, Viitanen PV, Poonian MS, Kaback HR. Site-specific mutagenesis of cysteine 148 to serine in the lac permease of Escherichia coli. The Journal of Biological Chemistry. 261: 8914-8. PMID 3087982  0.325
1986 Carrasco N, Antes LM, Poonian MS, Kaback HR. lac permease of Escherichia coli: histidine-322 and glutamic acid-325 may be components of a charge-relay system. Biochemistry. 25: 4486-8. PMID 2876725 DOI: 10.1021/Bi00364A004  0.351
1985 Carrasco N, Herzlinger D, Dechiara S, Danho W, Kaback HR. Topology of the lac permease protein in the membrane of Escherichia coli. Annals of the New York Academy of Sciences. 456: 305-6. PMID 3911839 DOI: 10.1111/j.1749-6632.1985.tb14880.x  0.321
1985 Padan E, Sarkar HK, Viitanen PV, Poonian MS, Kaback HR. Site-specific mutagenesis of histidine residues in the lac permease of Escherichia coli. Proceedings of the National Academy of Sciences of the United States of America. 82: 6765-8. PMID 3901007 DOI: 10.1073/pnas.82.20.6765  0.367
1985 Menick DR, Sarkar HK, Poonian MS, Kaback HR. cys154 Is important for lac permease activity in Escherichia coli. Biochemical and Biophysical Research Communications. 132: 162-70. PMID 2998353 DOI: 10.1016/0006-291X(85)91002-2  0.308
1984 Carrasco N, Herzlinger D, Mitchell R, DeChiara S, Danho W, Gabriel TF, Kaback HR. Intramolecular dislocation of the COOH terminus of the lac carrier protein in reconstituted proteoliposomes. Proceedings of the National Academy of Sciences of the United States of America. 81: 4672-6. PMID 6379649 DOI: 10.1073/pnas.81.15.4672  0.31
1984 Trumble WR, Viitanen PV, Sarkar HK, Poonian MS, Kaback HR. Site-directed mutagenesis of cys148 in the lac carrier protein of Escherichia coli. Biochemical and Biophysical Research Communications. 119: 860-7. PMID 6370251 DOI: 10.1016/0006-291X(84)90853-2  0.327
1984 Viitanen P, Garcia ML, Kaback HR. Purified reconstituted lac carrier protein from Escherichia coli is fully functional. Proceedings of the National Academy of Sciences of the United States of America. 81: 1629-33. PMID 6324209 DOI: 10.1073/pnas.81.6.1629  0.362
1984 Herzlinger D, Viitanen P, Carrasco N, Kaback HR. Monoclonal antibodies against the lac carrier protein from Escherichia coli. 2. Binding studies with membrane vesicles and proteoliposomes reconstituted with purified lac carrier protein. Biochemistry. 23: 3688-93. PMID 6206889 DOI: 10.1021/bi00311a018  0.318
1983 Carrasco N, Tahara SM, Patel L, Goldkorn T, Kaback HR. Preparation, characterization, and properties of monoclonal antibodies against the lac carrier protein from Escherichia coli. Proceedings of the National Academy of Sciences of the United States of America. 79: 6894-8. PMID 6757923 DOI: 10.1073/pnas.79.22.6894  0.309
1983 Goldkorn T, Rimon G, Kaback HR. Topology of the lac carrier protein in the membrane of Escherichia coli. Proceedings of the National Academy of Sciences of the United States of America. 80: 3322-6. PMID 6344081 DOI: 10.1073/pnas.80.11.3322  0.362
1983 Matsushita K, Patel L, Gennis RB, Kaback HR. Reconstitution of active transport in proteoliposomes containing cytochrome o oxidase and lac carrier protein purified from Escherichia coli. Proceedings of the National Academy of Sciences of the United States of America. 80: 4889-93. PMID 6308657 DOI: 10.1073/Pnas.80.16.4889  0.356
1983 Garcia ML, Patel L, Padan E, Kaback HR. Mechanism of lactose transport in Escherichia coli membrane vesicles: evidence for the involvement of histidine residue(s) in the response of the lac carrier to the proton electrochemical gradient. Biochemistry. 21: 5800-5. PMID 6295441 DOI: 10.1021/bi00266a012  0.369
1982 Santos E, Kung HF, Young IG, Kaback HR. In vitro synthesis of the membrane-bound D-lactate dehydrogenase of Escherichia coli Biochemistry. 21: 2085-2091. PMID 7046793 DOI: 10.1021/bi00538a016  0.305
1982 Patel L, Garcia ML, Kaback HR. Direct measurement of lactose/proton symport in Escherichia coli membrane vesicles: Further evidence for the involvement of histidine residue(s) Biochemistry. 21: 5805-5810. PMID 6295442 DOI: 10.1021/bi00266a013  0.341
1982 Haldar K, Olsiewski PJ, Walsh C, Kaczorowski GJ, Bhaduri A, Kaback HR. Simultaneous reconstitution of Escherichia coli membrane vesicles with D-lactate and D-amino acid dehydrogenases. Biochemistry. 21: 4590-6. PMID 6128026 DOI: 10.1021/Bi00262A012  0.469
1982 Olsiewski PJ, Kaczorowski GJ, Walsh CT, Kaback HR. Reconstitution of Escherichia coli membrane vesicles with D-amino acid dehydrogenase. Biochemistry. 20: 6272-9. PMID 6118175 DOI: 10.1021/bi00524a056  0.354
1981 Newman MJ, Foster DL, Wilson TH, Kaback HR. Purification and reconstitution of functional lactose carrier from Escherichia coli Journal of Biological Chemistry. 256: 11804-11808. PMID 7028742  0.324
1981 Cohn DE, Kaczorowski GJ, Kaback HR. Effect of the proton electrochemical gradient on maleimide inactivation of active transport in Escherichia coli membrane vesicles. Biochemistry. 20: 3308-13. PMID 7018574 DOI: 10.1021/bi00514a050  0.371
1981 Robertson DE, Kaczorowski GJ, Garcia ML, Kaback HR. Active transport in membrane vesicles from Escherichia coli: the electrochemical proton gradient alters the distribution of the lac carrier between two different kinetic states. Biochemistry. 19: 5692-702. PMID 7006690 DOI: 10.1021/bi00566a005  0.329
1981 Kaczorowski GJ, LeBlanc G, Kaback HR. Specific labeling of the lac carrier protein in membrane vesicles of Escherichia coli by a photoaffinity reagent. Proceedings of the National Academy of Sciences of the United States of America. 77: 6319-23. PMID 7005896 DOI: 10.1073/pnas.77.11.6319  0.367
1981 Hugenholtz J, Hong JS, Kaback HR. ATP-driven active transport in right-side-out bacterial membrane vesicles. Proceedings of the National Academy of Sciences of the United States of America. 78: 3446-9. PMID 6267592 DOI: 10.1073/pnas.78.6.3446  0.326
1980 Cohn DE, Kaback HR. Mechanism of the melibiose porter in membrane vesicles of Escherichia coli. Biochemistry. 19: 4237-43. PMID 6998495 DOI: 10.1021/bi00559a015  0.356
1980 Ramos S, Grollman EF, Lazo PS, Dyer SA, Habig WH, Hardegree MC, Kaback HR, Kohn LD. Effect of tetanus toxin on the accumulation of the permeant lipophilic cation tetraphenylphosphonium by guinea pig brain synaptosomes. Proceedings of the National Academy of Sciences of the United States of America. 76: 4783-7. PMID 291898 DOI: 10.1073/Pnas.76.10.4783  0.331
1980 Kaczorowski GJ, Robertson DE, Kaback HR. MECHANISM OF LACTOSE TRANSLOCATION IN MEMBRANE VESICLES FROM ESCHERICHIA COLI Annals of the New York Academy of Sciences. 341: 473-481. DOI: 10.1111/j.1749-6632.1980.tb47192.x  0.303
1980 OWEN P, KABACK HR, GRAEME-COOK KA. IDENTIFICATION OF ANTIGEN 19/27 AS DIHYDROLIPOYL DEHYDROGENASE AND ITS PROBABLE INVOLVEMENT IN UBIQUINONE-MEDIATED NADH-DEPENDENT TRANSPORT PHENOMENA IN MEMBRANE VESICLES OFESCHERICHIA COLI Fems Microbiology Letters. 7: 345-348. DOI: 10.1111/j.1574-6941.1980.tb01619.x  0.318
1979 Padan E, Patel L, Kaback HR. Effect of diethylpyrocarbonate on lactose/proton symport in Escherichia coli membrane vesicles Proceedings of the National Academy of Sciences of the United States of America. 76: 6221-6225. PMID 392515 DOI: 10.1073/pnas.76.12.6221  0.309
1979 Stroobant P, Kaback HR. Reconstitution of ubiquinone-linked functions in membrane vesicles from a double quinone mutant of Escherichia coli. Biochemistry. 18: 226-31. PMID 369597 DOI: 10.1021/bi00568a035  0.35
1979 Kaczorowski G, Kohn LD, Kaback HR. Purification and properties of D-lactate dehydrogenase from Escherichia coli ML 308-225. Methods in Enzymology. 53: 519-27. PMID 362128 DOI: 10.1016/S0076-6879(78)53054-1  0.382
1979 Lichtshtein D, Kaback HR, Blume AJ. Use of a lipophilic cation for determination of membrane potential in neuroblastoma-glioma hybrid cell suspensions. Proceedings of the National Academy of Sciences of the United States of America. 76: 650-4. PMID 284390 DOI: 10.1073/Pnas.76.2.650  0.309
1979 Owen P, Kaback HR. Antigenic architecture of membrane vesicles from Escherichia coli. Biochemistry. 18: 1422-6. PMID 218621 DOI: 10.1021/bi00575a005  0.3
1979 Owen P, Kaback HR. Immunochemical analysis of membrane vesicles from Escherichia coli. Biochemistry. 18: 1413-22. PMID 218620 DOI: 10.1021/bi00575a004  0.306
1979 Ramos S, Schuldiner S, Kaback HR. The use of flow dialysis for determinations of deltapH and active transport. Methods in Enzymology. 55: 680-8. PMID 37407 DOI: 10.1016/0076-6879(79)55076-9  0.35
1978 Kaback HR, Ramos S, Robertson DE, Stroobant P, Tokuda H. Energetics and molecular biology of active transport in bacterial membrane vesicles. Journal of Supramolecular Structure. 7: 443-61. PMID 357844 DOI: 10.1002/jss.400070315  0.39
1978 Kaback HR, Patel L. The role of functional sulfhydryl groups in active transport in Escherichia coli membrane vesicles Biochemistry. 17: 1640-1646. PMID 350273 DOI: 10.1021/Bi00602A010  0.393
1978 Owen P, Kaback HR. Molecular structure of membrane vesicles from Escherichia coli. Proceedings of the National Academy of Sciences of the United States of America. 75: 3148-52. PMID 150599 DOI: 10.1073/Pnas.75.7.3148  0.418
1977 Grollman EF, Lee G, Ambesi-Impiombato FS, Meldolesi MF, Aloj SM, Coon HG, Kaback HR, Kohn LD. Effects of thyrotropin on the thyroid cell membrane: hyperpolarization induced by hormone-receptor interaction. Proceedings of the National Academy of Sciences of the United States of America. 74: 2352-6. PMID 196288 DOI: 10.1073/Pnas.74.6.2352  0.37
1977 Ramos S, Kaback HR. The electrochemical proton gradient in Escherichia coli membrane vesicles and its relationship to active transport. Biochemical Society Transactions. 5: 23-5. PMID 19318 DOI: 10.1042/bst0050023  0.337
1977 Tokuda H, Kaback HR. Sodium-dependent methyl 1-thio-beta-D-galactopyranoside transport in membrane vesicles isolated from Salmonella typhimurium. Biochemistry. 16: 2130-6. PMID 16639 DOI: 10.1021/Bi00629A013  0.389
1977 Ramos S, Kaback HR. The relationship between the electrochemical proton gradient and active transport in Escherichia coli membrane vesicles. Biochemistry. 16: 854-9. PMID 14665 DOI: 10.1021/Bi00624A007  0.438
1977 Kaback HR. Molecular biology and energetics of membrane transport. Journal of Cellular Physiology. 89: 575-93. PMID 13080 DOI: 10.1002/jcp.1040890414  0.304
1976 Kaback HR. Transport studies in bacterial membrane vesicles. Science (New York, N.Y.). 186: 882-92. PMID 4620043 DOI: 10.1126/science.186.4167.882  0.373
1976 Rudnick G, Schuldiner S, Kaback HR. Equilibrium between two forms of the lac carrier protein in energized and nonenergized membrane vesicles from Escherichia coli Biochemistry. 15: 5126-5131. PMID 791364 DOI: 10.1021/bi00668a028  0.394
1976 Schuldiner S, Weil R, Kaback HR. Energy-dependent binding of dansylgalactoside to the lac carrier protein: direct binding measurements. Proceedings of the National Academy of Sciences of the United States of America. 73: 109-12. PMID 174094 DOI: 10.1073/Pnas.73.1.109  0.376
1976 Patel L, Kaback HR. The role of the carbodiimide-reactive component of the adenosine-5′-triphosphatase complex in the proton permeability of Escherichia coli membrane vesicles Biochemistry. 15: 2741-2746. PMID 132963 DOI: 10.1021/bi00658a005  0.312
1976 Boonstra J, Gutnick DL, Kaback HR. Physiological suppression of a transport defect in Escherichia coli mutants deficient in Ca2+, Mg2+-stimulated adenosine triphosphatase. Journal of Bacteriology. 124: 1248-55. PMID 127784 DOI: 10.1128/jb.124.3.1248-1255.1975  0.306
1976 Schuldiner S, Rudnick G, Weil R, Kaback HR. Mechanism of β-galactoside transport in Escherichia coli membrane vesicles Trends in Biochemical Sciences. 1: 41-45. DOI: 10.1016/S0968-0004(76)80181-8  0.302
1976 Schuldiner S, Rudnick G, Weil R, Kaback HR. Mechanism of β galactoside transport in Escherichia coli membrane vesicles Trends Biochem.Sci.. 1: 41-45. DOI: 10.1016/S0968-0004(76)80181-8  0.446
1975 Short SA, Kaback HR. Amino acid transport and staphylococcal membrane vesicles. Annals of the New York Academy of Sciences. 236: 124-43. PMID 4371336 DOI: 10.1111/j.1749-6632.1974.tb41487.x  0.3
1975 Schuldiner S, Spencer RD, Weber G, Weil R, Kaback HR. Lifetime and rotational relaxation time of dansylgalactoside bound to the lac carrier protein. The Journal of Biological Chemistry. 250: 8893-6. PMID 1104608  0.338
1975 Kaczorowski G, Kaback HR, Walsh C. Reversible inactivation of vectorial phosphorylation by hydroxybutynoate in Escherichia coli membrane vesicles. Biochemistry. 14: 3903-8. PMID 1100101 DOI: 10.1021/bi00688a026  0.374
1975 Rudnick G, Kaback HR. Photoinactivation of the beta-galactoside transport system in Escherichia coli membrane vesicles with an impermeant azidophenylgalactoside. The Journal of Biological Chemistry. 250: 6847-51. PMID 1099095  0.363
1975 Shaw L, Grau F, Kaback HR, Hong JS, Walsh C. Vinylglycolate resistance in Escherichia coli. Journal of Bacteriology. 121: 1047-55. PMID 1090585 DOI: 10.1128/Jb.121.3.1047-1055.1975  0.327
1975 Rudnick G, Kaback HR, Weil R. Photoinactivation of the beta-galactoside transport system in Escherichia coli membrane vesicles with 2-nitro-4-azidophenyl-1-thio-beta-D-galactopyranoside. The Journal of Biological Chemistry. 250: 1371-5. PMID 1089657  0.318
1975 Kaback HR, Rudnick G, Schuldiner S, Short SA. Active transport in isolated bacterial membrane vesicles: binding of beta-galactosides to the LAC carrier protein. Annals of the New York Academy of Sciences. 264: 350-7. PMID 769642 DOI: 10.1111/j.1749-6632.1975.tb31495.x  0.338
1975 Schuldiner S, Kaback HR. Membrane potential and active transport in membrane vesicles from Escherichia coli. Biochemistry. 14: 5451-61. PMID 172125 DOI: 10.1021/bi00696a011  0.329
1975 Patel L, Schuldiner S, Kaback HR. Reversible effects of chaotropic agents on the proton permeability of Escherichia coli membrane vesicles. Proceedings of the National Academy of Sciences of the United States of America. 72: 3387-91. PMID 171661 DOI: 10.1073/Pnas.72.9.3387  0.314
1975 Stroobant P, Kaback HR. Ubiquinone-mediated coupling of NADH dehydrogenase to active transport in membrane vesicles from Escherichia coli. Proceedings of the National Academy of Sciences of the United States of America. 72: 3970-4. PMID 672 DOI: 10.1073/pnas.72.10.3970  0.313
1974 Short SA, Kaback HR. Mechanisms of active transport in isolated bacterial membrane vesicles. Further studies on amino acid transport in Staphylococcus aureus membrane vesicles. The Journal of Biological Chemistry. 249: 4275-81. PMID 4853134  0.326
1974 Short SA, Kaback HR, Kaczorowski G, Fisher J, Walsh CT, Silverstein SC. Determination of the absolute number of Escherichia coli membrane vesicles that catalyze active transport Proceedings of the National Academy of Sciences of the United States of America. 71: 5032-5036. PMID 4612538 DOI: 10.1073/Pnas.71.12.5032  0.319
1974 Cox GS, Kaback HR, Weissbach H. Defective transport in S-adenosylmethionine synthetase mutants of Escherichia coli Archives of Biochemistry and Biophysics. 161: 610-620. PMID 4599317 DOI: 10.1016/0003-9861(74)90344-0  0.354
1974 Short SA, Kaback HR, Kohn LD. D-lactate dehydrogenase binding in Escherichia coli dld- membrane vesicles reconstituted for active transport. Proceedings of the National Academy of Sciences of the United States of America. 71: 1461-5. PMID 4598306 DOI: 10.1073/Pnas.71.4.1461  0.447
1974 Kaback HR. Active transport in bacterial cytoplasmic membrane vesicles. Symposia of the Society For Experimental Biology. 27: 145-74. PMID 4594375  0.322
1974 Lombardi FJ, Reeves JP, Short SA, Kaback HR. Evaluation of the chemiosmotic interpretation of active transport in bacterial membrane vesicles. Annals of the New York Academy of Sciences. 227: 312-27. PMID 4363926 DOI: 10.1111/j.1749-6632.1974.tb14396.x  0.302
1973 Short SA, White DC, Kaback HR. Mechanisms of active transport in isolated bacterial membrane vesicles. IX. The kinetics and specificity of amino acid transport in Staphylococcus aureus membrane vesicles. The Journal of Biological Chemistry. 247: 7452-8. PMID 4636316  0.335
1973 Kohn LD, Kaback HR. Mechanisms of active transport in isolated bacterial membrane vesicles Journal of Biological Chemistry. 248: 7012-7017. PMID 4582730  0.303
1973 Kaback HR. Transport across isolated bacterial cytoplasmic membranes. Biochimica Et Biophysica Acta. 265: 367-416. PMID 4581579 DOI: 10.1016/0304-4157(72)90014-7  0.306
1973 Lombardi FJ, Reeves JP, Kaback HR. Mechanisms of active transport in isolated bacterial membrane vesicles. 8. Valinomycin-induced rubidium transport. The Journal of Biological Chemistry. 248: 3551-65. PMID 4573982  0.303
1973 Reeves JP, Lombardi FJ, Kaback HR. Mechanisms of active transport in isolated bacterial membrane vesicles. VII. Fluorescence of 1-anilino-8-naphthalenesulfonate during D-lactate oxidation by membrane vesicles from Escherichia coli. The Journal of Biological Chemistry. 247: 6204-11. PMID 4568608  0.304
1973 Lombardi FJ, Kaback HR. Mechanisms of active transport in isolated bacterial membrane vesicles. 8. The transport of amino acids by membranes prepared from Escherichia coli. The Journal of Biological Chemistry. 247: 7844-57. PMID 4344983  0.343
1973 Prezioso G, Hong JS, Kerwar GK, Kaback HR. Mechanisms of active transport in isolated bacterial membrane vesicles. XII. Active transport by a mutant of Escherichia coli uncoupled for oxidative phosphorylation. Archives of Biochemistry and Biophysics. 154: 575-82. PMID 4266260 DOI: 10.1016/0003-9861(73)90011-8  0.316
1972 Kaback HR. Discussion paper: bacterial transport mechanisms as studied in cytoplasmic membrane vesicles. Annals of the New York Academy of Sciences. 195: 407-11. PMID 4624659  0.308
1972 Kerwar GK, Gordon AS, Kaback HR. Mechanisms of active transport in isolated membrane vesicles. IV. Galactose transport by isolated membrane vesicles from Escherichia coli. The Journal of Biological Chemistry. 247: 291-7. PMID 4623127  0.317
1972 Walsh CT, Abeles RH, Kaback HR. Mechanisms of active transport in isolated bacterial membrane vesicles. X. Inactivation of D-lactate dehydrogenase and D-lactate dehydrogenase-coupled transport in Escherichia coli membrane vesicles by an acetylenic substrate. The Journal of Biological Chemistry. 247: 7858-63. PMID 4565667  0.329
1972 Short SA, White DC, Kaback HR. Active transport in isolated bacterial membrane vesicles. V. The transport of amino acids by membrane vesicles prepared from Staphylococcus aureus. The Journal of Biological Chemistry. 247: 298-304. PMID 4553437  0.325
1972 Gordon AS, Lombardi FJ, Kaback HR. Solubilization and partial purification of amino acid-specific components of the D-lactate dehydrogenase-coupled amino acid-transport systems (E. coli-cell membranes-sephadex-detergent-solubilized-vesicles). Proceedings of the National Academy of Sciences of the United States of America. 69: 358-62. PMID 4333978 DOI: 10.1073/pnas.69.2.358  0.336
1971 Kaback HR, Barnes EM. Mechanisms of active transport in isolated membrane vesicles. II. The mechanism of energy coupling between D-lactic dehydrogenase and beta-galactoside transport in membrane preparations from Escherichia coli. The Journal of Biological Chemistry. 246: 5523-31. PMID 4941946  0.314
1971 Barnes EM, Kaback HR. Mechanisms of active transport in isolated membrane vesicles. I. The site of energy coupling between D-lactic dehydrogenase and beta-galactoside transport in Escherichia coli membrane vesicles. The Journal of Biological Chemistry. 246: 5518-22. PMID 4330922  0.328
1970 Weissbach H, Redfield B, Kaback HR. Nucleotide binding by Escherichia coli membranes and solubilized membrane proteins. Archives of Biochemistry and Biophysics. 135: 66-74. PMID 4903242 DOI: 10.1016/0003-9861(69)90517-7  0.36
1970 Barnes EM, Kaback HR. Beta-galactoside transport in bacterial membrane preparations: energy coupling via membrane-bounded D-lactic dehydrogenase. Proceedings of the National Academy of Sciences of the United States of America. 66: 1190-8. PMID 4394455 DOI: 10.1073/Pnas.66.4.1190  0.316
1969 Kaback HR, Deuel F. Proline uptake by disrupted membrane preparations from Escherichia coli. Archives of Biochemistry and Biophysics. 132: 118-29. PMID 4893409 DOI: 10.1016/0003-9861(69)90343-9  0.316
1968 Kaback HR. The role of the phosphoenolpyruvate-phosphotransferase system in the transport of sugars by isolated membrane preparations of Escherichia coli. The Journal of Biological Chemistry. 243: 3711-24. PMID 4872728  0.32
1968 Kaback HR, Stadtman ER. Glycine uptake in Escherichia coli. II. Glycine uptake, exchange, and metabolism by an isolated membrane preparation. The Journal of Biological Chemistry. 243: 1390-400. PMID 4869559  0.513
1966 Kaback HR, Stadtman ER. Proline uptake by an isolated cytoplasmic membrane preparation of Escherichia coli. Proceedings of the National Academy of Sciences of the United States of America. 55: 920-7. PMID 5327072 DOI: 10.1073/pnas.55.4.920  0.536
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