Frank A. Welsh - Publications

Affiliations: 
University of Pennsylvania, Philadelphia, PA, United States 
Area:
Neuroscience Biology

76 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2011 Sansing LH, Kasner SE, McCullough L, Agarwal P, Welsh FA, Kariko K. Autologous blood injection to model spontaneous intracerebral hemorrhage in mice. Journal of Visualized Experiments : Jove. PMID 21876533 DOI: 10.3791/2618  0.337
2006 Muramatsu H, Welsh FA, Karikó K. Cerebral preconditioning using cortical application of hypertonic salt solutions: upregulation of mRNAs encoding inhibitors of inflammation. Brain Research. 1097: 31-8. PMID 16725117 DOI: 10.1016/J.Brainres.2006.04.067  0.405
2005 Kariko K, Muramatsu H, Welsh FA. Cortical spreading depression elevates mRNAs encoding feedback inhibitors of inflammation: A novel mechanism of induced tolerance to ischemia Journal of Cerebral Blood Flow & Metabolism. 25: S283-S283. DOI: 10.1038/Sj.Jcbfm.9591524.0283  0.332
2004 Karikó K, Weissman D, Welsh FA. Inhibition of toll-like receptor and cytokine signaling--a unifying theme in ischemic tolerance. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 24: 1288-304. PMID 15545925 DOI: 10.1097/01.Wcb.0000145666.68576.71  0.317
2004 Muramatsu H, Karikó K, Welsh FA. Induction of tolerance to focal ischemia in rat brain: dissociation between cortical lesioning and spreading depression. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 24: 1167-71. PMID 15529017 DOI: 10.1097/01.Wcb.0000134714.38679.2C  0.425
2004 Otori T, Friedland JC, Sinson G, McIntosh TK, Raghupathi R, Welsh FA. Traumatic brain injury elevates glycogen and induces tolerance to ischemia in rat brain. Journal of Neurotrauma. 21: 707-18. PMID 15253799 DOI: 10.1089/0897715041269623  0.499
2003 Lifshitz J, Friberg H, Neumar RW, Raghupathi R, Welsh FA, Janmey P, Saatman KE, Wieloch T, Grady MS, McIntosh TK. Structural and functional damage sustained by mitochondria after traumatic brain injury in the rat: evidence for differentially sensitive populations in the cortex and hippocampus. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 23: 219-31. PMID 12571453 DOI: 10.1097/01.Wcb.0000040581.43808.03  0.375
2003 Otori T, Greenberg JH, Welsh FA. Cortical spreading depression causes a long-lasting decrease in cerebral blood flow and induces tolerance to permanent focal ischemia in rat brain. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 23: 43-50. PMID 12500090 DOI: 10.1097/01.Wcb.0000035180.38851.38  0.503
2001 Mitchell K, Karikó K, Harris VA, Rangel Y, Keller JM, Welsh FA. Preconditioning with cortical spreading depression does not upregulate Cu/Zn-SOD or Mn-SOD in the cerebral cortex of rats. Brain Research. Molecular Brain Research. 96: 50-8. PMID 11731008 DOI: 10.1016/S0169-328X(01)00266-2  0.55
2001 Neumar RW, Meng FH, Mills AM, Xu YA, Zhang C, Welsh FA, Siman R. Calpain activity in the rat brain after transient forebrain ischemia. Experimental Neurology. 170: 27-35. PMID 11421581 DOI: 10.1006/Exnr.2001.7708  0.429
2001 Rangel YM, Karikó K, Harris VA, Duvall ME, Welsh FA. Dose-dependent induction of mRNAs encoding brain-derived neurotrophic factor and heat-shock protein-72 after cortical spreading depression in the rat Molecular Brain Research. 88: 103-112. PMID 11295236 DOI: 10.1016/S0169-328X(01)00037-7  0.399
2001 Karikó K, Keller JM, Harris VA, Langer DJ, Welsh FA. In vivo protein expression from mRNA delivered into adult rat brain. Journal of Neuroscience Methods. 105: 77-86. PMID 11166368 DOI: 10.1016/S0165-0270(00)00355-1  0.347
2000 Murphy SJ, Song D, Welsh FA, Wilson DF, Pastuszko A. Regional expression of heat shock protein 72 MRNA following mild and severe hypoxia in neonatal piglet brain Advances in Experimental Medicine and Biology. 471: 155-163. PMID 10659143 DOI: 10.1007/978-1-4615-4717-4_19  0.449
1999 Kesavulu V, Keller J, Helfaer MA, McIntosh TK, Welsh F, Raghupathi R. Hypoxic hypoxemia increases mortality and morbidity with mild experimental traumatic brain injury Critical Care Medicine. 27: A63. DOI: 10.1097/00003246-199912001-00146  0.312
1998 Welsh FA. Mechanisms of induced tolerance to cerebral ischemia Nippon Ika Daigaku Zasshi. 65: 447-449. PMID 9893447 DOI: 10.1272/Jnms1923.65.447  0.44
1998 Karikó K, Harris VA, Rangel Y, Duvall ME, Welsh FA. Effect of cortical spreading depression on the levels of mRNA coding for putative neuroprotective proteins in rat brain Journal of Cerebral Blood Flow and Metabolism. 18: 1308-1315. PMID 9850143 DOI: 10.1097/00004647-199812000-00005  0.415
1998 Bronner G, Mitchell K, Welsh FA. Cerebrovascular adaptation after unilateral carotid artery ligation in the rat: preservation of blood flow and ATP during forebrain ischemia. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 18: 118-21. PMID 9428312 DOI: 10.1097/00004647-199801000-00012  0.631
1997 Bordelon YM, Chesselet MF, Nelson D, Welsh F, EreciÅ„ska M. Energetic dysfunction in quinolinic acid-lesioned rat striatum. Journal of Neurochemistry. 69: 1629-39. PMID 9326292 DOI: 10.1046/J.1471-4159.1997.69041629.X  0.308
1997 Detre JA, Zager EL, Alsop DC, Harris VA, Welsh FA. Correlation of diffusion MRI and heat shock protein in a rat embolic stroke model. Journal of the Neurological Sciences. 148: 163-9. PMID 9129112 DOI: 10.1016/S0022-510X(97)05368-9  0.407
1996 Murphy SJ, Song D, Welsh FA, Wilson DF, Pastuszko A. The effect of hypoxia and catecholamines on regional expression of heat-shock protein-72 mRNA in neonatal piglet brain Brain Research. 727: 145-152. PMID 8842392 DOI: 10.1016/0006-8993(96)00363-0  0.418
1995 Raghupathi R, Welsh FA, Lowenstein DH, Gennarelli TA, McIntosh TK. Regional induction of c-fos and heat shock protein-72 mRNA following fluid-percussion brain injury in the rat. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 15: 467-73. PMID 7714005 DOI: 10.1038/Jcbfm.1995.58  0.405
1995 Kobayashi S, Harris VA, Welsh FA. Spreading depression induces tolerance of cortical neurons to ischemia in rat brain Journal of Cerebral Blood Flow and Metabolism. 15: 721-727. PMID 7673367 DOI: 10.1038/Jcbfm.1995.92  0.433
1995 Shaver EG, Welsh FA, Sutton LN, Mora G, Gennarelli LM, Norwood CR. Deep hypothermia diminishes the ischemic induction of heat-shock protein-72 mRNA in piglet brain Stroke. 26: 1273-1278. PMID 7604425 DOI: 10.1161/01.Str.26.7.1273  0.447
1995 Hylton CM, Pesenson MA, Welsh FA. Adaptive preservation of ATP and tolerance to hypoxia following carotid artery ligation in the immature rat. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 15: 1137-40. PMID 7593347 DOI: 10.1038/Jcbfm.1995.141  0.428
1995 Kobayashi S, Welsh FA. Regional alterations of ATP and heat-shock protein-72 mRNA following hypoxia-ischemia in neonatal rat brain Journal of Cerebral Blood Flow and Metabolism. 15: 1047-1056. PMID 7593337 DOI: 10.1038/Jcbfm.1995.131  0.471
1994 Welsh FA. Regional expression of immediate-early genes and heat-shock genes after cerebral ischemia Annals of the New York Academy of Sciences. 723: 318-327. PMID 8030875 DOI: 10.1111/J.1749-6632.1994.Tb36737.X  0.343
1994 Glazier SS, O'Rourke DM, Graham DI, Welsh FA. Induction of ischemic tolerance following brief focal ischemia in rat brain. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 14: 545-53. PMID 8014201 DOI: 10.1038/Jcbfm.1994.68  0.503
1992 Greenberg JH, Hamar J, Welsh FA, Harris V, Reivich M. Effect of ischemia and reperfusion on lambda of the lumped constant of the [14C]deoxyglucose technique. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 12: 70-7. PMID 1727144 DOI: 10.1038/Jcbfm.1992.9  0.447
1992 Welsh FA, Moyer DJ, Harris VA. Regional expression of heat shock protein-70 mRNA and c-fos mRNA following focal ischemia in rat brain Journal of Cerebral Blood Flow and Metabolism. 12: 204-212. PMID 1548293 DOI: 10.1038/Jcbfm.1992.30  0.462
1992 Moyer DJ, Welsh FA, Zager EL. Spontaneous cerebral hypothermia diminishes focal infarction in rat brain Stroke. 23: 1812-1816. PMID 1448833 DOI: 10.1161/01.Str.23.12.1812  0.459
1992 Blumenfeld KS, Welsh FA, Harris VA, Pesenson MA. Regional expression of c-fos and heat shock protein-70 mRNA following hypoxia-ischemia in immature rat brain. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 12: 987-95. PMID 1400653 DOI: 10.1038/Jcbfm.1992.136  0.43
1991 Welsh FA, Harris VA. Postischemic hypothermia fails to reduce ischemic injury in gerbil hippocampus Journal of Cerebral Blood Flow and Metabolism. 11: 617-620. PMID 2050749 DOI: 10.1038/Jcbfm.1991.112  0.359
1991 Welsh FA, Marcy VR, Sims RE. NADH fluorescence and regional energy metabolites during focal ischemia and reperfusion of rat brain Journal of Cerebral Blood Flow and Metabolism. 11: 459-465. PMID 2016354 DOI: 10.1038/Jcbfm.1991.88  0.485
1990 Gregory GA, Welsh FA, Yu ACH, Chan PH. Fructose-1,6-bisphosphate reduces ATP loss from hypoxic astrocytes Brain Research. 516: 310-312. PMID 2364296 DOI: 10.1016/0006-8993(90)90932-2  0.359
1990 Welsh FA, Sims RE, Harris VA. Mild hypothermia prevents ischemic injury in gerbil hippocampus Journal of Cerebral Blood Flow and Metabolism. 10: 557-563. PMID 2347886 DOI: 10.1038/Jcbfm.1990.98  0.379
1990 Sutton LN, Greenberg J, Welsh F. Blood flow and metabolism in vasogenic oedema. Acta Neurochirurgica. 51: 397-400. PMID 2089951 DOI: 10.1007/978-3-7091-9115-6_133  0.382
1989 Katayama Y, Welsh FA. Effect of Dichloroacetate on Regional Energy Metabolites and Pyruvate Dehydrogenase Activity During Ischemia and Reperfusion in Gerbil Brain Journal of Neurochemistry. 52: 1817-1822. PMID 2723637 DOI: 10.1111/J.1471-4159.1989.Tb07262.X  0.516
1989 Sutton LN, Barranco D, Greenberg J, Dante S, Florin S, Welsh F. Cerebral blood flow and glucose metabolism in experimental brain edema Journal of Neurosurgery. 71: 868-874. PMID 2585079 DOI: 10.3171/Jns.1989.71.6.0868  0.391
1987 Welsh FA, Sakamoto T, McKee AE, Sims RE. Effect of lactacidosis on pyridine nucleotide stability during ischemia in mouse brain. Journal of Neurochemistry. 49: 846-51. PMID 3612129 DOI: 10.1111/J.1471-4159.1987.Tb00971.X  0.511
1986 Lesnick JE, Coyer PE, Michele JJ, Welsh FA, Simeone FA. Comparison of the somatosensory evoked potential and the direct cortical response following severe incomplete global ischemia: Selective vulnerability of the white matter conduction pathways Stroke. 17: 1247-1250. PMID 3810728 DOI: 10.1161/01.Str.17.6.1247  0.437
1986 Colohan ART, Welsh FA, Miller ED, Kassell NF. The Effect of dichloroacetate on brain lactate levels following incomplete ichemia in the hyperglycemic rat Stroke. 17: 525-528. PMID 3715955 DOI: 10.1161/01.Str.17.3.525  0.491
1985 Tanaka K, Welsh FA, Greenberg JH, O'Flynn R, Harris VA, Reivich M. Regional alterations in glucose consumption and metabolite levels during postischemic recovery in cat brain Journal of Cerebral Blood Flow and Metabolism. 5: 502-511. PMID 3932373 DOI: 10.1038/Jcbfm.1985.76  0.421
1985 Welsh FA. Role of vascular factors in regional ischemic injury Progress in Brain Research. 63: 19-27. PMID 3915125 DOI: 10.1016/S0079-6123(08)61972-X  0.446
1984 Lesnick JE, Michele JJ, Simeone FA, DeFeo S, Welsh FA. Alteration of somatosensory evoked potentials in response to global ischemia Journal of Neurosurgery. 60: 490-494. PMID 6699692 DOI: 10.3171/Jns.1984.60.3.0490  0.446
1984 Marcy VR, Welsh FA. Correlation between cerebral blood flow and ATP content following tourniquet-induced ischemia in cat brain Journal of Cerebral Blood Flow and Metabolism. 4: 362-367. PMID 6470054 DOI: 10.1038/Jcbfm.1984.53  0.514
1984 Welsh FA. Regional evaluation of ischemic metabolic alterations Journal of Cerebral Blood Flow and Metabolism. 4: 309-316. PMID 6381515 DOI: 10.1038/Jcbfm.1984.46  0.44
1983 Welsh FA, Sims RE, McKee AE. Effect of glucose on recovery of energy metabolism following hypoxia-oligemia in mouse brain: dose-dependence and carbohydrate specificity. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 3: 486-92. PMID 6630318 DOI: 10.1038/Jcbfm.1983.75  0.484
1982 Welsh FA, Vannucci RC, Brierley JB. Columnar alterations of NADH fluorescence during hypoxia-ischemia in immature rat brain Journal of Cerebral Blood Flow and Metabolism. 2: 221-228. PMID 7076734 DOI: 10.1038/Jcbfm.1982.22  0.44
1982 Welsh FA, O'Connor MJ, Marcy VR, Spatacco AJ, Johns RL. Factors limiting regeneration of ATP following temporary ischemia in cat brain. Stroke; a Journal of Cerebral Circulation. 13: 234-42. PMID 7064195 DOI: 10.1161/01.Str.13.2.234  0.482
1982 Keykhah MM, Welsh FA, Hagerdal M, Harp JR. Reduction of the cerebral protective effect of hypothermia by oligemic hypotension during hypoxia in the rat Stroke. 13: 171-174. PMID 6801824 DOI: 10.1161/01.Str.13.2.171  0.493
1981 Berntman L, Welsh FA, Harp JR. Cerebral protective effect of low-grade hypothermia Anesthesiology. 55: 495-498. PMID 7294402 DOI: 10.1097/00132586-198210000-00018  0.425
1980 Welsh FA, Ginsberg MD, Rieder W, Budd WW. Deleterious effect of glucose pretreatment on recovery from diffuse cerebral ischemia in the cat: II. Regional metabolite levels Stroke. 11: 355-363. PMID 7414663 DOI: 10.1161/01.Str.11.4.355  0.487
1980 Ginsberg MD, Welsh FA, Budd WW. Deleterious effect of glucose pretreatment on recovery from diffuse cerebral ischemiain the cat: I. Local cerebral blood flow and glucose utilization Stroke. 11: 347-354. PMID 7414662 DOI: 10.1161/01.Str.11.4.347  0.495
1980 Welsh FA, Greenberg JH, Jones SC, Ginsberg MD, Reivich M. Correlation between glucose utilization and metabolite levels during focal ischemia in cat brain Stroke. 11: 79-84. PMID 7355435 DOI: 10.1161/01.Str.11.1.79  0.424
1980 Keykhah MM, Hagerdal M, Welsh FA, Barrer MA, Sisco F, Harp JR. Effect of high vs low arterial blood oxygen content on cerebral energy metabolite levels during hypoxia with normothermia and hypothermia in the rat Anesthesiology. 52: 492-495. PMID 6769365 DOI: 10.1097/00000542-198006000-00008  0.339
1980 Keykhah MM, Berntman L, Welsh FA, Harp JR. EFFECTS OF CHANGE IN ARTERIAL CO2 TENSION ON BRAIN ENERGY LEVEL DURING INDUCED HYPOTENSION Anesthesiology. 53: S244. DOI: 10.1097/00000542-198009001-00244  0.372
1980 Welsh FA. Pathophysiology of cerebral energy and metabolism Electroencephalography and Clinical Neurophysiology. 50: 530. DOI: 10.1016/0013-4694(80)90022-X  0.372
1979 Keykhah MM, Welsh FA, Harp JR. Cerebral energy levels during trimethaphan-induced hypotension in the rat: Effects of light versus deep halothane anesthesia Anesthesiology. 50: 36-39. PMID 760601 DOI: 10.1097/00000542-197901000-00008  0.428
1979 Ginsberg MD, Graham DI, Welsh FA, Budd WW. Diffuse cerebral ischemia in the cat: III. Neuropathological sequelae of severe ischemia Annals of Neurology. 5: 350-358. PMID 443769 DOI: 10.1002/Ana.410050408  0.536
1979 Berntman L, Welsh FA, BianRosa IJ, Harp JR. Diazepam fails to protect brain tissue in hypoxic stress Anesthesiology. 51. DOI: 10.1097/00000542-197909001-00202  0.44
1979 WELSH FA, SHAPIRO HM. Brain Energy Metabolism Anesthesiology. 50: 376. DOI: 10.1097/00000542-197904000-00027  0.34
1978 Keykhah MM, Welsh FA, Miller AS, Harp JR, DeFeo SP. Cerebral energy metabolite levels and survival following exposure to low inspired oxygen concentration Critical Care Medicine. 6: 330-334. PMID 720089 DOI: 10.1097/00003246-197809000-00007  0.481
1978 Hagerdal M, Welsh FA, Keykhah MM, Perez E, Harp JR. Protective effects of combinations of hypothermia and barbiturates in cerebral hypoxia in the rat Anesthesiology. 49: 165-169. PMID 686437 DOI: 10.1097/00000542-197809000-00003  0.458
1978 Welsh FA, Ginsberg MD, Rieder W, Budd WW. Diffuse cerebral ischemia in the cat: II. Regional metabolites during severe ischemia and recirculation Annals of Neurology. 3: 493-501. PMID 677815 DOI: 10.1002/Ana.410030606  0.512
1978 Ginsberg MD, Budd WW, Welsh FA. Diffuse cerebral ischemia in the cat: I. Local blood flow during severe ischemia and recirculation Annals of Neurology. 3: 482-492. PMID 677814 DOI: 10.1002/Ana.410030605  0.496
1978 Welsh FA, O'Connor MJ, Marcy VR. EFFECT OF OLIGEMIA ON REGIONAL METABOLITE LEVELS IN CAT BRAIN Journal of Neurochemistry. 31: 311-319. PMID 209145 DOI: 10.1111/J.1471-4159.1978.Tb12464.X  0.488
1978 Welsh FA, Rieder W. EVALUATION OF IN SITU FREEZING OF CAT BRAIN BY NADH FLUORESCENCE Journal of Neurochemistry. 31: 299-309. PMID 209144 DOI: 10.1111/J.1471-4159.1978.Tb12463.X  0.415
1978 Welsh FA, Ginsberg MD, Rieder W, Budd WW. Impairment of metabolic recovery from cerebral ischemia by prior administration of glucose Federation Proceedings. 37.  0.31
1977 Pickard JD, Durity F, Welsh FA, Langfitt TW, Harper AM, MacKenzie ET. Osmotic opening of the blood-brain barrier: value in pharmacological studies on the cerebral circulation. Brain Research. 122: 170-6. PMID 402173 DOI: 10.1016/0006-8993(77)90676-X  0.302
1977 Ginsberg MD, Welsh FA, Budd WW. Abnormalities of brain flow and metabolism during recovery from diffuse cerebral ischemia: dependence upon duration of ischemia Acta Neurologica Scandinavica, Supplement. 64: 126-127. PMID 268756  0.371
1977 Welsh FA, O'Connor MJ, Langfitt TW. Regions of cerebral ischemia located by pyridine nucleotide fluorescence Science. 198: 951-953. PMID 201026 DOI: 10.1126/Science.201026  0.423
1977 Welsh FA, O'Connor MJ, Rieder W, Marcy VR. Regional changes in metabolism in hypoxia-ischemia Advances in Experimental Medicine and Biology. 78: 275-286. PMID 197809 DOI: 10.1007/978-1-4615-9035-4_23  0.478
1977 Welsh FA, Durity F, Langfitt TW. THE APPEARANCE OF REGIONAL VARIATIONS IN METABOLISM AT A CRITICAL LEVEL OF DIFFUSE CEREBRAL OLIGEMIA Journal of Neurochemistry. 28: 71-79. PMID 188986 DOI: 10.1111/J.1471-4159.1977.Tb07710.X  0.45
1975 Marshall LF, Welsh F, Durity F, Lounsbury R, Graham DI, Langfitt TW. Experimental cerebral oligemia and ischemia produced by intracranial hypertension. Part 3: Brain energy metabolism. Journal of Neurosurgery. 43: 323-8. PMID 1151468 DOI: 10.3171/Jns.1975.43.3.0323  0.441
1975 Marshall LF, Graham DI, Durity F, Lounsbury R, Welsh F, Langfitt TW. Experimental cerebral oligemia and ischemia produced by intracranial hypertension. Part 2: Brain morphology. Journal of Neurosurgery. 43: 318-22. PMID 1151467 DOI: 10.3171/Jns.1975.43.3.0318  0.487
1975 Marshall LF, Durity F, Lounsbury R, Graham DI, Welsh F, Langfitt TW. Experimental cerebral oligemia and ischemia produced by intracranial hypertension. Part 1: Pathophysiology, electroencephalography, cerebral blood flow, blood-brain barrier, and neurological function. Journal of Neurosurgery. 43: 308-17. PMID 1151466 DOI: 10.3171/Jns.1975.43.3.0308  0.474
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