Avital Schurr - Publications

Affiliations: 
University of Louisville, Louisville, KY, United States 
Area:
Pharmacology, Neuroscience Biology

79 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Schurr A. Glycolysis Paradigm Shift Dictates a Reevaluation of Glucose and Oxygen Metabolic Rates of Activated Neural Tissue. Frontiers in Neuroscience. 12: 700. PMID 30364172 DOI: 10.3389/Fnins.2018.00700  0.354
2017 Gozal E, Miller CJ, Dematteis M, Sachleben LR, Schurr A, Rane MJ. PKA activity exacerbates hypoxia-induced ROS formation and hypoxic injury in PC-12 cells. Toxicology Letters. PMID 28751209 DOI: 10.1016/J.Toxlet.2017.07.895  0.311
2015 El-Mallakh RS, Payne RS, Schurr A, Gao Y, Lei Z, Kiss B, Gyertyán I, Adham N. Cariprazine delays ouabain-evoked epileptiform spikes and loss of activity in rat hippocampal slices. Psychiatry Research. 229: 370-3. PMID 26160196 DOI: 10.1016/J.Psychres.2015.05.114  0.683
2015 Schurr A, Gozal E. Glycolysis at 75: is it time to tweak the first elucidated metabolic pathway in history? Frontiers in Neuroscience. 9: 170. PMID 26029042 DOI: 10.3389/Fnins.2015.00170  0.307
2014 Schurr A. Cerebral glycolysis: a century of persistent misunderstanding and misconception. Frontiers in Neuroscience. 8: 360. PMID 25477776 DOI: 10.3389/Fnins.2014.00360  0.341
2011 Schurr A, Gozal E. Aerobic production and utilization of lactate satisfy increased energy demands upon neuronal activation in hippocampal slices and provide neuroprotection against oxidative stress. Frontiers in Pharmacology. 2: 96. PMID 22275901 DOI: 10.3389/Fphar.2011.00096  0.45
2011 Gao Y, Payne RS, Schurr A, Hougland T, Lord J, Herman L, Lei Z, Banerjee P, El-Mallakh RS. Memantine reduces mania-like symptoms in animal models. Psychiatry Research. 188: 366-71. PMID 21269711 DOI: 10.1016/J.Psychres.2010.12.030  0.655
2008 Schurr A. Lactate: a major and crucial player in normal function of both muscle and brain. The Journal of Physiology. 586: 2665-6. PMID 18515304 DOI: 10.1113/Jphysiol.2008.155416  0.323
2008 Schurr A, Payne RS. The glucose paradox of cerebral ischemia - a possible resolution Journal of Neurochemistry. 81: 108-111. DOI: 10.1046/J.1471-4159.81.S1.42_15.X  0.71
2007 Payne RS, Schurr A. Corticosterone disrupts glucose-, but not lactate-supported hippocampal PS-LTP. Neuroscience Letters. 424: 111-5. PMID 17709185 DOI: 10.1016/J.Neulet.2007.07.006  0.724
2007 Schurr A, Payne RS. Lactate, not pyruvate, is neuronal aerobic glycolysis end product: an in vitro electrophysiological study. Neuroscience. 147: 613-9. PMID 17560727 DOI: 10.1016/J.Neuroscience.2007.05.002  0.69
2006 Schurr A. Lactate: the ultimate cerebral oxidative energy substrate? Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 26: 142-52. PMID 15973352 DOI: 10.1038/Sj.Jcbfm.9600174  0.361
2005 Payne RS, Akca O, Roewer N, Schurr A, Kehl F. Sevoflurane-induced preconditioning protects against cerebral ischemic neuronal damage in rats. Brain Research. 1034: 147-52. PMID 15713266 DOI: 10.1016/J.Brainres.2004.12.006  0.724
2005 Payne RS, Schurr A. The stress hormone corticosterone inhibits glucose-, but not lactate-supported hippocampal LTP Journal of Cerebral Blood Flow & Metabolism. 25: S67-S67. DOI: 10.1038/Sj.Jcbfm.9591524.0067  0.649
2004 Payne RS, Goldbart A, Gozal D, Schurr A. Effect of intermittent hypoxia on long-term potentiation in rat hippocampal slices. Brain Research. 1029: 195-9. PMID 15542074 DOI: 10.1016/J.Brainres.2004.09.045  0.685
2004 Kehl F, Payne RS, Roewer N, Schurr A. Sevoflurane-induced preconditioning of rat brain in vitro and the role of KATP channels. Brain Research. 1021: 76-81. PMID 15328034 DOI: 10.1016/J.Brainres.2004.06.038  0.718
2003 Goldbart A, Row BW, Kheirandish L, Schurr A, Gozal E, Guo SZ, Payne RS, Cheng Z, Brittian KR, Gozal D. Intermittent hypoxic exposure during light phase induces changes in cAMP response element binding protein activity in the rat CA1 hippocampal region: water maze performance correlates. Neuroscience. 122: 585-90. PMID 14622901 DOI: 10.1016/J.Neuroscience.2003.08.054  0.666
2003 Payne RS, Tseng MT, Schurr A. The glucose paradox of cerebral ischemia: evidence for corticosterone involvement. Brain Research. 971: 9-17. PMID 12691832 DOI: 10.1016/S0006-8993(03)02276-5  0.706
2003 Tseng MT, Chan SA, Schurr A. Ischemia-induced changes in monocarboxylate transporter 1 reactive cells in rat hippocampus. Neurological Research. 25: 83-6. PMID 12564131 DOI: 10.1179/016164103101200978  0.305
2003 Akça O, Payne RS, Kehl F, Sessler DI, Schurr A. HYPERCAPNIC ACIDOSIS PRECONDITIONS BRAIN SLICES TO HYPOXIA Anesthesiology. 99: B12. DOI: 10.1097/00000542-200309001-00002  0.647
2003 Schurr A, Payne RS. Hyperglycemia and neuronal damage in cerebral ischemia and beyond Critical Care and Shock. 6: 184-190.  0.687
2002 Schurr A. Bench-to-bedside review: a possible resolution of the glucose paradox of cerebral ischemia. Critical Care (London, England). 6: 330-4. PMID 12225609 DOI: 10.1186/Cc1520  0.464
2002 Schurr A. Lactate, glucose and energy metabolism in the ischemic brain (Review). International Journal of Molecular Medicine. 10: 131-6. PMID 12119547 DOI: 10.3892/Ijmm.10.2.131  0.4
2002 Schurr A. Energy metabolism, stress hormones and neural recovery from cerebral ischemia/hypoxia. Neurochemistry International. 41: 1-8. PMID 11918966 DOI: 10.1016/S0197-0186(01)00142-5  0.405
2002 Schurr A. Lactate, glucose and hypoxic/ischemic brain injury Critical Care and Shock. 5: 3-8.  0.38
2001 Schurr A, Payne RS, Miller JJ, Tseng MT. Preischemic hyperglycemia-aggravated damage: evidence that lactate utilization is beneficial and glucose-induced corticosterone release is detrimental. Journal of Neuroscience Research. 66: 782-9. PMID 11746402 DOI: 10.1002/Jnr.10065  0.732
2001 Schurr A. Glucose and the ischemic brain: A sour grape or a sweet treat? Current Opinion in Clinical Nutrition and Metabolic Care. 4: 287-292. PMID 11458022 DOI: 10.1097/00075197-200107000-00007  0.404
2001 Reid KH, Li GY, Payne RS, Schurr A, Cooper NG. The mRNA level of the potassium-chloride cotransporter KCC2 covaries with seizure susceptibility in inferior colliculus of the post-ischemic audiogenic seizure-prone rat. Neuroscience Letters. 308: 29-32. PMID 11445278 DOI: 10.1016/S0304-3940(01)01973-5  0.624
2001 Schurr A, Payne RS, Tseng MT, Gozal E, Gozal D. Excitotoxic preconditioning elicited by both glutamate and hypoxia and abolished by lactate transport inhibition in rat hippocampal slices. Neuroscience Letters. 307: 151-4. PMID 11438386 DOI: 10.1016/S0304-3940(01)01937-1  0.693
2001 Gozal E, Row BW, Schurr A, Gozal D. Developmental differences in cortical and hippocampal vulnerability to intermittent hypoxia in the rat Neuroscience Letters. 305: 197-201. PMID 11403939 DOI: 10.1016/S0304-3940(01)01853-5  0.322
2001 Payne RS, Schurr A. Corticosterone-aggravated ischemic neuronal damage in vitro is relieved by vanadate. Neuroreport. 12: 1261-3. PMID 11338203 DOI: 10.1097/00001756-200105080-00041  0.689
2001 Schurr A, Payne RS, Miller JJ, Tseng MT, Rigor BM. Blockade of lactate transport exacerbates delayed neuronal damage in a rat model of cerebral ischemia. Brain Research. 895: 268-72. PMID 11259789 DOI: 10.1016/S0006-8993(01)02082-0  0.723
2000 El-Mallakh RS, Schurr A, Payne RS, Li R. Ouabain induction of cycling of multiple spike responses in hippocampal slices is delayed by lithium. Journal of Psychiatric Research. 34: 115-20. PMID 10758252 DOI: 10.1016/S0022-3956(99)00045-X  0.667
1999 Schurr A, Payne RS, Tseng MT, Miller JJ, Rigor BM. The glucose paradox in cerebral ischemia. New insights. Annals of the New York Academy of Sciences. 893: 386-90. PMID 10672274 DOI: 10.1111/J.1749-6632.1999.Tb07862.X  0.698
1999 Schurr A, Payne RS, Miller JJ, Rigor BM. Study of cerebral energy metabolism using the rat hippocampal slice preparation. Methods (San Diego, Calif.). 18: 117-26. PMID 10356342 DOI: 10.1006/Meth.1999.0765  0.699
1999 Li MM, Payne RS, Reid KH, Tseng MT, Rigor BM, Schurr A. Correlates of delayed neuronal damage and neuroprotection in a rat model of cardiac-arrest-induced cerebral ischemia. Brain Research. 826: 44-52. PMID 10216195 DOI: 10.1016/S0006-8993(99)01221-4  0.692
1999 Schurr A, Miller JJ, Payne RS, Rigor BM. An increase in lactate output by brain tissue serves to meet the energy needs of glutamate-activated neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 34-9. PMID 9870935 DOI: 10.1523/Jneurosci.19-01-00034.1999  0.726
1998 Chan SA, Reid KH, Schurr A, Miller JJ, Iyer V, Tseng MT. Fosphenytoin reduces hippocampal neuronal damage in rat following transient global ischemia. Acta Neurochirurgica. 140: 175-80. PMID 10398998 DOI: 10.1007/S007010050080  0.481
1998 Schurr A, Rigor BM. Brain anaerobic lactate production: A suicide note or a survival kit? Developmental Neuroscience. 20: 348-357. PMID 9778571 DOI: 10.1159/000017330  0.39
1998 Rigor BM, Schurr A, Miller JJ, Payne RS. NEURONS ENDURE EXCITATION BY GLUTAMATE VIA UTILIZATION OF GLIA-GENERATED LACTATE AS AEROBIC FUEL Anesthesiology. 89: 760A. DOI: 10.1097/00000542-199809130-00066  0.659
1997 Schurr A, Payne RS, Miller JJ, Rigor BM. Glia are the main source of lactate utilized by neurons for recovery of function posthypoxia. Brain Research. 774: 221-4. PMID 9452213 DOI: 10.1016/S0006-8993(97)81708-8  0.704
1997 Schurr A, Payne RS, Miller JJ, Rigor BM. Brain lactate is an obligatory aerobic energy substrate for functional recovery after hypoxia: further in vitro validation. Journal of Neurochemistry. 69: 423-6. PMID 9202338 DOI: 10.1046/J.1471-4159.1997.69010423.X  0.709
1997 Schurr A, Payne RS, Miller JJ, Rigor BM. Brain lactate, not glucose, fuels the recovery of synaptic function from hypoxia upon reoxygenation: an in vitro study. Brain Research. 744: 105-11. PMID 9030418 DOI: 10.1016/S0006-8993(96)01106-7  0.698
1997 Rigor &, Schurr A, Payne R, Miller J. A709 LACTATE Anesthesiology. 87: 709A. DOI: 10.1097/00000542-199709001-00709  0.572
1996 Payne RS, Schurr A, Rigor BM. Cell swelling exacerbates hypoxic neuronal damage in rat hippocampal slices. Brain Research. 723: 210-3. PMID 8813401 DOI: 10.1016/0006-8993(96)00254-5  0.73
1996 Reid KH, Young C, Schurr A, Tseng M, Payne RS, Keelen P, Miller J, Iyer V. Audiogenic seizures following global ischemia induced by chest compression in Long-Evans rats Epilepsy Research. 23: 195-209. PMID 8739123 DOI: 10.1016/0920-1211(95)00099-2  0.653
1996 Schurr A, Payne RS, Levy RS, Rigor BM. Understanding cerebral energy metabolism: A key to successful neuroprotection Bailliere's Clinical Anaesthesiology. 10: 409-425. DOI: 10.1016/S0950-3501(96)80026-2  0.66
1995 Schurr A, Payne RS, Reid KH, Iyer V, Tseng MT, Li MM, Chan SA, Young C, Miller JJ, Rigor BM. Cardiac arrest-induced global cerebral ischemia studied in vitro. Life Sciences. 57: 2425-30. PMID 8847963 DOI: 10.1016/0024-3205(95)02238-7  0.719
1995 Schurr A, Payne RS, Rigor BM. Synergism between diltiazem and MK-801 but not APV in protecting hippocampal slices against hypoxic damage. Brain Research. 684: 233-6. PMID 7583230 DOI: 10.1016/0006-8993(95)00466-4  0.677
1995 Schurr A, Payne RS, Rigor BM. Protection by MK-801 against hypoxia-, excitotoxin-, and depolarization-induced neuronal damage in vitro. Neurochemistry International. 26: 519-25. PMID 7492949 DOI: 10.1016/0197-0186(94)00148-N  0.712
1995 Schurr A, Payne RS, Heine MF, Rigor BM. Hypoxia, excitotoxicity, and neuroprotection in the hippocampal slice preparation. Journal of Neuroscience Methods. 59: 129-38. PMID 7475243 DOI: 10.1016/0165-0270(94)00203-S  0.707
1994 Schurr A, Payne R, Rigor B. 15. The pharmacology of excitotoxins and hypoxia in hippocampal slices Journal of Neuroscience Methods. 52: A7. DOI: 10.1016/0165-0270(94)90075-2  0.684
1993 Schurr A, West CA, Heine MF, Rigor BM. The neurotoxicity of sulfur-containing amino acids in energy-deprived rat hippocampal slices. Brain Research. 601: 317-20. PMID 8431779 DOI: 10.1016/0006-8993(93)91728-B  0.46
1993 Schurr A, Rigor BM. Quinolinate potentiates the neurotoxicity of excitatory amino acids in hypoxic neuronal tissue in vitro Brain Research. 617: 76-80. PMID 8397046 DOI: 10.1016/0006-8993(93)90615-T  0.391
1993 Schurr A, Rigor BM. Kainate toxicity in energy-compromised rat hippocampal slices: differences between oxygen and glucose deprivation Brain Research. 614: 10-14. PMID 7688644 DOI: 10.1016/0006-8993(93)91011-G  0.474
1993 Schurr A, Rigor BM. The mechanism of cerebral hypoxic-ischemic damage. Hippocampus. 2: 221-8. PMID 1308186 DOI: 10.1002/Hipo.450020303  0.379
1992 Schurr A, West CA, Rigor BM. Neurotoxicity of quinolinic acid and its derivatives in hypoxic rat hippocampal slices. Brain Research. 568: 199-204. PMID 1687668 DOI: 10.1016/0006-8993(91)91398-K  0.387
1992 Schurr A, West CA, Rigor BM. The excitotoxicity of heterocyclic dicarboxyclic acids in rat hippocampal slices: structure-activity relationships Brain Research. 571: 145-148. PMID 1611487 DOI: 10.1016/0006-8993(92)90521-A  0.401
1992 Rigor BM, West CA, Schurr A. QUINOLINATE POTENTIATES THE TOXICITY OF EXCITATORY AMINO ACIDS DURING CEREBRAL HYPOXIA IN VITRO Anesthesiology. 77: A736. DOI: 10.1097/00000542-199209001-00736  0.326
1989 Schurr A, West CA, Rigor BM. Electrophysiology of energy metabolism and neuronal function in the hippocampal slice preparation. Journal of Neuroscience Methods. 28: 7-13. PMID 2725015 DOI: 10.1016/0165-0270(89)90004-6  0.473
1989 Lucas LF, West CA, Rigor BM, Schurr A. Protection against cerebral hypoxia by local anesthetics: a study using brain slices. Journal of Neuroscience Methods. 28: 47-50. PMID 2725014 DOI: 10.1016/0165-0270(89)90008-3  0.479
1989 Schurr A, Rigor BM. Cerebral ischemia revisited: new insights as revealed using in vitro brain slice preparations. Experientia. 45: 684-95. PMID 2668016 DOI: 10.1007/BF01974560  0.322
1988 Schurr A, Rigor BM. The mechanism of neuronal resistance and adaptation to hypoxia. Febs Letters. 224: 4-8. PMID 3678493 DOI: 10.1016/0014-5793(87)80411-8  0.374
1988 Schurr A, West CA, Rigor BM. Lactate-supported synaptic function in the rat hippocampal slice preparation. Science (New York, N.Y.). 240: 1326-8. PMID 3375817 DOI: 10.1126/Science.3375817  0.442
1988 Dong WQ, Schurr A, Reid KH, Shields CB, West CA. The rat hippocampal slice preparation as an in vitro model of ischemia. Stroke. 19: 498-502. PMID 3363578 DOI: 10.1161/01.Str.19.4.498  0.504
1988 Schurr A, Dong WQ, Reid KH, West CA, Rigor BM. Lactic acidosis and recovery of neuronal function following cerebral hypoxia in vitro. Brain Research. 438: 311-4. PMID 3345436 DOI: 10.1016/0006-8993(88)91354-6  0.472
1988 Reid KH, Edmonds HL, Schurr A, Tseng MT, West CA. Pitfalls in the use of brain slices. Progress in Neurobiology. 31: 1-18. PMID 3287453 DOI: 10.1016/0301-0082(88)90020-2  0.342
1987 Schurr A, West CA, Reid KH, Tseng MT, Reiss SJ, Rigor BM. Increased glucose improves recovery of neuronal function after cerebral hypoxia in vitro. Brain Research. 421: 135-9. PMID 3690263 DOI: 10.1016/0006-8993(87)91283-2  0.472
1987 Schurr A, Changaris DG, Rigor BM. Glutamine protects neuronal function against cerebral hypoxia: a study using the in vitro hippocampal slice preparation. Brain Research. 412: 179-81. PMID 3607453 DOI: 10.1016/0006-8993(87)91457-0  0.46
1987 Schurr A, Tseng MT, West CA, Rigor BM. Taurine improves the recovery of neuronal function following cerebral hypoxia: an in vitro study. Life Sciences. 40: 2059-66. PMID 3586851 DOI: 10.1016/0024-3205(87)90098-1  0.464
1987 Rigor BM, Dong W-, Brahen NH, West CA, Schurr A. THE HOLE OF LACTIC ACIDOSIS IN NEURONAL TISSUE DAMAGE INFLICTED BY HYPOXIA IN VITRO Anesthesiology. 67: A322. DOI: 10.1097/00000542-198709001-00322  0.366
1986 Schurr A, Spears B, Reid KH, West CA, Edmonds HL, Rigor BM. Lidocaine depresses synaptic activity in the rat hippocampal slice. Anesthesiology. 64: 501-3. PMID 3963457 DOI: 10.1097/00000542-198604000-00015  0.35
1986 Schurr A, Reid KH, Tseng MT, West C, Rigor BM. Adaptation of adult brain tissue to anoxia and hypoxia in vitro. Brain Research. 374: 244-8. PMID 3719335 DOI: 10.1016/0006-8993(86)90418-X  0.396
1986 Schurr A, West CA, Reid KH, Tseng MT, Rigor BM. HYPERGLYCEMIA IMPROVES RECOVERY FROM CEREBRAL HYPOXIA Anesthesiology. 65: A315. DOI: 10.1097/00000542-198609001-00313  0.327
1985 Schurr A, Reid KH, Tseng MT, Edmonds HL, Rigor BM. A dual chamber for comparative studies using the brain slice preparation. Comparative Biochemistry and Physiology. a, Comparative Physiology. 82: 701-4. PMID 2866894 DOI: 10.1016/0300-9629(85)90454-2  0.372
1984 Reid KH, Schurr A, Tseng MT, Edmonds HL. Resistance to hypoxia in the rat hippocampal slice. Brain Research. 302: 387-91. PMID 6329464 DOI: 10.1016/0006-8993(84)90255-5  0.38
1984 Schurr A, Reid KH, Tseng MT, Edmonds HL. The stability of the hippocampal slice preparation: an electrophysiological and ultrastructural analysis. Brain Research. 297: 357-62. PMID 6326943 DOI: 10.1016/0006-8993(84)90576-6  0.378
1982 Schurr A, Rigor BM, Ho BT, Dafny N. Electrophysiological support in favor of multiple opiate receptors in the caudate and the central gray of the rat Comparative Biochemistry and Physiology. Part C, Comparative. 73: 323-330. PMID 6129100 DOI: 10.1016/0306-4492(82)90129-0  0.366
1982 Schurr A, Rigor BM, Ho BT, Dafny N. Caudate neuronal response to microiontophoretically injected morphine in naive and morphine-dependent rats Comparative Biochemistry and Physiology. Part C, Comparative. 73: 205-209. PMID 6128174 DOI: 10.1016/0306-4492(82)90192-7  0.383
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