| Year |
Citation |
Score |
| 2020 |
Hannigan KI, Bossey AP, Foulkes HJL, Drumm BT, Baker SA, Ward SM, Sanders KM, Keef KD, Cobine CA. A novel intramuscular Interstitial Cell of Cajal is a candidate for generating pacemaker activity in the mouse internal anal sphincter. Scientific Reports. 10: 10378. PMID 32587396 DOI: 10.1038/S41598-020-67142-Y |
0.731 |
|
| 2019 |
Cobine CA, Hannigan KI, McMahon M, Ni Bhraonain EP, Baker SA, Keef KD. Rhythmic calcium transients in smooth muscle cells of the mouse internal anal sphincter. Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society. e13746. PMID 31625250 DOI: 10.1111/Nmo.13746 |
0.755 |
|
| 2019 |
Keef K, Cobine C. Generation of Spontaneous Tone by Gastrointestinal Sphincters. Advances in Experimental Medicine and Biology. 1124: 47-74. PMID 31183822 DOI: 10.1007/978-981-13-5895-1_2 |
0.734 |
|
| 2019 |
Keef KD, Cobine CA. Control of Motility in the Internal Anal Sphincter. Journal of Neurogastroenterology and Motility. PMID 30827084 DOI: 10.5056/Jnm18172 |
0.751 |
|
| 2018 |
Cobine CA, McKechnie M, Brookfield RJ, Hannigan KI, Keef KD. Comparison of inhibitory neuromuscular transmission in the Cynomolgus monkey IAS and rectum: special emphasis on differences in purinergic transmission. The Journal of Physiology. 596: 5319-5341. PMID 30198065 DOI: 10.1113/Jp275437 |
0.743 |
|
| 2018 |
Baker SA, Drumm BT, Cobine CA, Keef KD, Sanders KM. Inhibitory Neural Regulation of the Ca Transients in Intramuscular Interstitial Cells of Cajal in the Small Intestine. Frontiers in Physiology. 9: 328. PMID 29686622 DOI: 10.3389/Fphys.2018.00328 |
0.74 |
|
| 2017 |
Cobine CA, Hannah EE, Zhu MH, Lyle HE, Rock JR, Sanders KM, Ward SM, Keef KD. ANO1 in intramuscular interstitial cells of Cajal plays a key role in the generation of slow waves and tone in the internal anal sphincter. The Journal of Physiology. PMID 28054347 DOI: 10.1113/Jp273618 |
0.767 |
|
| 2016 |
Keef KD, Ward SM, Cobine CA. AB285. SPR-12 Evidence supporting a pivotal role for intramuscular interstitial cells of Cajal in the generation of pacemaker activity, phasic contractions and tone in the internal anal sphincter Translational Andrology and Urology. 5: AB285-AB285. DOI: 10.21037/Tau.2016.S285 |
0.727 |
|
| 2015 |
Sanders KM, Keef KD. Cellular mediators of nitrergic neurotransmission in GI smooth muscles: no easy answer. The Journal of Physiology. 593: 4511-2. PMID 26466754 DOI: 10.1113/Jp271320 |
0.43 |
|
| 2015 |
Cobine CA, Hannah EE, Sotherton AG, Kirchoff I, Ward SM, Keef KD. 65 Role of ANO1 in Slow Wave and Tone Generation in the Internal Anal Sphincter Gastroenterology. 148: S-19. DOI: 10.1016/S0016-5085(15)30065-2 |
0.672 |
|
| 2014 |
Cobine CA, Sotherton AG, Peri LE, Sanders KM, Ward SM, Keef KD. Nitrergic neuromuscular transmission in the mouse internal anal sphincter is accomplished by multiple pathways and postjunctional effector cells. American Journal of Physiology. Gastrointestinal and Liver Physiology. 307: G1057-72. PMID 25301187 DOI: 10.1152/Ajpgi.00331.2014 |
0.742 |
|
| 2014 |
Hall KA, Ward SM, Cobine CA, Keef KD. Spatial organization and coordination of slow waves in the mouse anorectum. The Journal of Physiology. 592: 3813-29. PMID 24951622 DOI: 10.1113/Jphysiol.2014.272542 |
0.747 |
|
| 2013 |
Keef KD, Saxton SN, McDowall RA, Kaminski RE, Duffy AM, Cobine CA. Functional role of vasoactive intestinal polypeptide in inhibitory motor innervation in the mouse internal anal sphincter. The Journal of Physiology. 591: 1489-506. PMID 23339175 DOI: 10.1113/Jphysiol.2012.247684 |
0.741 |
|
| 2012 |
Duffy AM, Cobine CA, Keef KD. Changes in neuromuscular transmission in the W/W(v) mouse internal anal sphincter. Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society. 24: e41-55. PMID 22074497 DOI: 10.1111/J.1365-2982.2011.01806.X |
0.719 |
|
| 2011 |
Cobine CA, Hennig GW, Kurahashi M, Sanders KM, Ward SM, Keef KD. Relationship between interstitial cells of Cajal, fibroblast-like cells and inhibitory motor nerves in the internal anal sphincter. Cell and Tissue Research. 344: 17-30. PMID 21337122 DOI: 10.1007/S00441-011-1138-1 |
0.744 |
|
| 2010 |
Cobine CA, Hennig GW, Bayguinov YR, Hatton WJ, Ward SM, Keef KD. Interstitial cells of Cajal in the cynomolgus monkey rectoanal region and their relationship to sympathetic and nitrergic nerves. American Journal of Physiology. Gastrointestinal and Liver Physiology. 298: G643-56. PMID 20150245 DOI: 10.1152/Ajpgi.00260.2009 |
0.744 |
|
| 2008 |
McDonnell B, Hamilton R, Fong M, Ward SM, Keef KD. Functional evidence for purinergic inhibitory neuromuscular transmission in the mouse internal anal sphincter. American Journal of Physiology. Gastrointestinal and Liver Physiology. 294: G1041-51. PMID 18308858 DOI: 10.1152/Ajpgi.00356.2007 |
0.418 |
|
| 2008 |
McKechnie M, Harvey N, Cobine CA, Keef K. W1352 Comparison of Inhibitory Motor Innervation in the Primate and Mouse Internal Anal Sphincter Gastroenterology. 134: A-686. DOI: 10.1016/S0016-5085(08)63202-3 |
0.693 |
|
| 2008 |
Cobine CA, Bayguinov Y, Ward SM, Keef K. 716 Distribution of Interstitial Cells of Cajal in the Primate Rectoanal Region and Their Relationship to Sympathetic and Nitrergic Nerves Gastroenterology. 134: A-102. DOI: 10.1016/S0016-5085(08)60478-3 |
0.703 |
|
| 2008 |
Harvey N, McDonnell B, McKechnie M, Keef K. 475 Role of L-Type Calcium Channels, Membrane Potential and Nitric Oxide in the Control of Myogenic Activity in the Primate Internal Anal Sphincter Gastroenterology. 134: A-63. DOI: 10.1016/S0016-5085(08)60299-1 |
0.344 |
|
| 2007 |
Cobine CA, Fong M, Hamilton R, Keef KD. Species dependent differences in the actions of sympathetic nerves and noradrenaline in the internal anal sphincter. Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society. 19: 937-45. PMID 17973631 DOI: 10.1111/J.1365-2982.2007.00982.X |
0.747 |
|
| 2007 |
Lee HT, Hennig GW, Fleming NW, Keef KD, Spencer NJ, Ward SM, Sanders KM, Smith TK. Septal interstitial cells of Cajal conduct pacemaker activity to excite muscle bundles in human jejunum. Gastroenterology. 133: 907-17. PMID 17678922 DOI: 10.1053/J.Gastro.2007.06.024 |
0.429 |
|
| 2007 |
Lee HT, Hennig GW, Fleming NW, Keef KD, Spencer NJ, Ward SM, Sanders KM, Smith TK. The mechanism and spread of pacemaker activity through myenteric interstitial cells of Cajal in human small intestine. Gastroenterology. 132: 1852-65. PMID 17484879 DOI: 10.1053/J.Gastro.2007.02.049 |
0.375 |
|
| 2007 |
Cobine CA, Callaghan BP, Keef KD. Role of L-type calcium channels and PKC in active tone development in rabbit coronary artery. American Journal of Physiology. Heart and Circulatory Physiology. 292: H3079-88. PMID 17277031 DOI: 10.1152/Ajpheart.01261.2006 |
0.763 |
|
| 2006 |
Callaghan B, Zhong J, Keef KD. Signaling pathway underlying stimulation of L-type Ca2+ channels in rabbit portal vein myocytes by recombinant Gbetagamma subunits. American Journal of Physiology. Heart and Circulatory Physiology. 291: H2541-6. PMID 16877561 DOI: 10.1152/Ajpheart.00420.2006 |
0.623 |
|
| 2006 |
Ro S, Kang SH, Farrelly AM, Ordog T, Partain R, Fleming N, Sanders KM, Kenyon JL, Keef KD. Template switching within exons 3 and 4 of KV11.1 (HERG) gives rise to a 5' truncated cDNA. Biochemical and Biophysical Research Communications. 345: 1342-9. PMID 16723117 DOI: 10.1016/J.Bbrc.2006.05.032 |
0.726 |
|
| 2005 |
Lee HK, Ro S, Keef KD, Kathy KD, Kim YH, Kim HW, Horowitz B, Sanders KM. Differential expression of P2X-purinoceptor subtypes in circular and longitudinal muscle of canine colon. Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society. 17: 575-84. PMID 16078947 DOI: 10.1111/J.1365-2982.2005.00670.X |
0.359 |
|
| 2004 |
Callaghan B, Koh SD, Keef KD. Muscarinic M2 receptor stimulation of Cav1.2b requires phosphatidylinositol 3-kinase, protein kinase C, and c-Src. Circulation Research. 94: 626-33. PMID 14739158 DOI: 10.1161/01.Res.0000118248.17466.B7 |
0.59 |
|
| 2003 |
Farrelly AM, Ro S, Callaghan BP, Khoyi MA, Fleming N, Horowitz B, Sanders KM, Keef KD. Expression and function of KCNH2 (HERG) in the human jejunum. American Journal of Physiology. Gastrointestinal and Liver Physiology. 284: G883-95. PMID 12736144 DOI: 10.1152/Ajpgi.00394.2002 |
0.778 |
|
| 2003 |
Mutafova-Yambolieva VN, O'Driscoll K, Farrelly A, Ward SM, Keef KD. Spatial localization and properties of pacemaker potentials in the canine rectoanal region. American Journal of Physiology. Gastrointestinal and Liver Physiology. 284: G748-55. PMID 12540368 DOI: 10.1152/Ajpgi.00295.2002 |
0.37 |
|
| 2003 |
Horiguchi K, Keef KD, Ward SM. Distribution of interstitial cells of Cajal in tunica muscularis of the canine rectoanal region. American Journal of Physiology. Gastrointestinal and Liver Physiology. 284: G756-67. PMID 12540367 DOI: 10.1152/Ajpgi.00294.2002 |
0.367 |
|
| 2002 |
Tichenor SD, Buxton IL, Johnson P, O'Driscoll K, Keef KD. Excitatory motor innervation in the canine rectoanal region: role of changing receptor populations. British Journal of Pharmacology. 137: 1321-9. PMID 12466242 DOI: 10.1038/Sj.Bjp.0704987 |
0.394 |
|
| 2002 |
Ward SM, Gershon MD, Keef K, Bayguinov YR, Nelson C, Sanders KM. Interstitial cells of Cajal and electrical activity in ganglionic and aganglionic colons of mice. American Journal of Physiology. Gastrointestinal and Liver Physiology. 283: G445-56. PMID 12121893 DOI: 10.1152/Ajpgi.00475.2001 |
0.367 |
|
| 2002 |
Keef KD, Anderson U, O'Driscoll K, Ward SM, Sanders KM. Electrical activity induced by nitric oxide in canine colonic circular muscle. American Journal of Physiology. Gastrointestinal and Liver Physiology. 282: G123-9. PMID 11751165 DOI: 10.1152/Ajpgi.00217.2001 |
0.438 |
|
| 2001 |
Keef KD, Hume JR, Zhong J. Regulation of cardiac and smooth muscle Ca2+ channels (Cav1.2a,b) by protein kinases American Journal of Physiology - Cell Physiology. 281. PMID 11698232 DOI: 10.1152/Ajpcell.2001.281.6.C1743 |
0.365 |
|
| 2001 |
Mutafova-Yambolieva VN, Keef KD. Frequency dependent α2-adrenoceptor mediated modulation of excitatory junction potentials in guinea-pig mesenteric artery European Journal of Pharmacology. 411: 123-127. PMID 11137866 DOI: 10.1016/S0014-2999(00)00905-5 |
0.319 |
|
| 2001 |
Fukao M, Mason HS, Kenyon JL, Horowitz B, Keef KD. Regulation of BK(Ca) channels expressed in human embryonic kidney 293 cells by epoxyeicosatrienoic acid. Molecular Pharmacology. 59: 16-23. PMID 11125019 DOI: 10.1124/Mol.59.1.16 |
0.379 |
|
| 2000 |
Smyth L, Bobalova J, Ward SM, Keef KD, Mutafova-Yambolieva VN. Cotransmission from sympathetic vasoconstrictor neurons: Differences in guinea-pig mesenteric artery and vein Autonomic Neuroscience: Basic and Clinical. 86: 18-29. PMID 11269921 DOI: 10.1016/S1566-0702(00)00203-4 |
0.342 |
|
| 1999 |
Zhong J, Hume JR, Keef KD. Anchoring protein is required for cAMP-dependent stimulation of L-type Ca2+ channels in rabbit portal vein American Journal of Physiology - Cell Physiology. 277. PMID 10516114 DOI: 10.1152/Ajpcell.1999.277.4.C840 |
0.418 |
|
| 1999 |
Bayguinov O, Keef KD, Hagen B, Sanders KM. Parallel pathways mediate inhibitory effects of vasoactive intestinal polypeptide and nitric oxide in canine fundus British Journal of Pharmacology. 126: 1543-1552. PMID 10323585 DOI: 10.1038/Sj.Bjp.0702450 |
0.368 |
|
| 1999 |
Zhong J, Dessauer CW, Keef KD, Hume JR. Regulation of L-type Ca2+ channels in rabbit portal vein by G protein α(s) and βγ subunits Journal of Physiology. 517: 109-120. PMID 10226153 DOI: 10.1111/J.1469-7793.1999.0109Z.X |
0.413 |
|
| 1999 |
Fukao M, Mason HS, Britton FC, Kenyon JL, Horowitz B, Keef KD. Cyclic GMP-dependent protein kinase activates cloned BKCa channels expressed in mammalian cells by direct phosphorylation at serine 1072. The Journal of Biological Chemistry. 274: 10927-35. PMID 10196172 DOI: 10.1074/Jbc.274.16.10927 |
0.397 |
|
| 1998 |
Rae MG, Khoyi MA, Keef KD. Modulation of cholinergic neuromuscular transmission by nitric oxide in canine colonic circular smooth muscle. American Journal of Physiology. Gastrointestinal and Liver Physiology. 275: G1324-G1332. PMID 29585769 DOI: 10.1152/ajpgi.1998.275.6.G1324 |
0.334 |
|
| 1998 |
Rae MG, Khoyi MA, Keef KD. Modulation of cholinergic neuromuscular transmission by nitric oxide in canine colonic circular smooth muscle. The American Journal of Physiology. 275: G1324-32. PMID 9843769 DOI: 10.1152/Ajpgi.1998.275.6.G1324 |
0.443 |
|
| 1998 |
Koh SD, Bradley KK, Rae MG, Keef KD, Horowitz B, Sanders KM. Basal activation of ATP-sensitive potassium channels in murine colonic smooth muscle cell. Biophysical Journal. 75: 1793-800. PMID 9746521 DOI: 10.1016/S0006-3495(98)77621-0 |
0.439 |
|
| 1998 |
Eckman DM, Hopkins N, McBride C, Keef KD. Endothelium-dependent relaxation and hyperpolarization in guinea-pig coronary artery: Role of epoxyeicosatrienoic acid British Journal of Pharmacology. 124: 181-189. PMID 9630358 DOI: 10.1038/Sj.Bjp.0701778 |
0.347 |
|
| 1998 |
Rae MG, Fleming N, McGregor DB, Sanders KM, Keef KD. Control of motility patterns in the human colonic circular muscle layer by pacemaker activity Journal of Physiology. 510: 309-320. PMID 9625887 DOI: 10.1111/J.1469-7793.1998.309Bz.X |
0.443 |
|
| 1998 |
Ruiz-Velasco V, Zhong J, Hume JR, Keef KD. Modulation of Ca2+ channels by cyclic nucleotide cross activation of opposing protein kinases in rabbit portal vein Circulation Research. 82: 557-565. PMID 9529160 DOI: 10.1161/01.Res.82.5.557 |
0.407 |
|
| 1997 |
Mutafova-Yambolieva VN, Keef KD. Adenosine-induced hyperpolarization in guinea pig coronary artery involves A(2b) receptors and K(ATP) channels American Journal of Physiology - Heart and Circulatory Physiology. 273. PMID 9435605 DOI: 10.1152/Ajpheart.1997.273.6.H2687 |
0.327 |
|
| 1997 |
Keef KD, Murray DC, Sanders KM, Smith TK. Basal release of nitric oxide induces an oscillatory motor pattern in canine colon Journal of Physiology. 499: 773-786. PMID 9130172 DOI: 10.1113/Jphysiol.1997.Sp021968 |
0.477 |
|
| 1996 |
Khoyi MA, Ishikawa T, Keef KD, Westfall DP. Ca(2+)-induced inhibition of 45Ca2+ influx and Ca2+ current in smooth muscle of the rat vas deferens. The American Journal of Physiology. 270: C1468-77. PMID 8967449 DOI: 10.1152/Ajpcell.1996.270.5.C1468 |
0.32 |
|
| 1994 |
Eckman DM, Weinert JS, Buxton ILO, Keef KD. Cyclic GMP‐independent relaxation and hyperpolarization with acetylcholine in guinea‐pig coronary artery British Journal of Pharmacology. 111: 1053-1060. PMID 8032590 DOI: 10.1111/J.1476-5381.1994.Tb14851.X |
0.339 |
|
| 1994 |
Keef KD, Shuttleworth CW, Xue C, Bayguinov O, Publicover NG, Sanders KM. Relationship between nitric oxide and vasoactive intestinal polypeptide in enteric inhibitory neurotransmission. Neuropharmacology. 33: 1303-14. PMID 7870287 DOI: 10.1016/0028-3908(94)90030-2 |
0.464 |
|
| 1993 |
Smith TK, Ward SM, Zhang L, Buxton ILO, Gerthoffer WT, Sanders KM, Keef KD. β-Adrenergic inhibition of electrical and mechanical activity in canine colon: Role of cAMP American Journal of Physiology - Gastrointestinal and Liver Physiology. 264. PMID 8386465 DOI: 10.1152/Ajpgi.1993.264.4.G708 |
0.433 |
|
| 1993 |
Ishikawa T, Hume JR, Keef KD. Regulation of Ca2+ channels by cAMP and cGMP in vascular smooth muscle cells Circulation Research. 73: 1128-1137. PMID 8222084 DOI: 10.1161/01.Res.73.6.1128 |
0.414 |
|
| 1993 |
Keef KD, Du C, Ward SM, McGregor B, Sanders KM. Enteric inhibitory neural regulation of human colonic circular muscle: Role of nitric oxide Gastroenterology. 105: 1009-1016. PMID 8104837 DOI: 10.1016/0016-5085(93)90943-7 |
0.452 |
|
| 1993 |
Shuttleworth CW, Sanders KM, Keef KD. Inhibition of nitric oxide synthesis reveals non-cholinergic excitatory neurotransmission in the canine proximal colon. British Journal of Pharmacology. 109: 739-47. PMID 7689401 DOI: 10.1111/J.1476-5381.1993.Tb13636.X |
0.427 |
|
| 1993 |
Gelband CH, Ishikawa T, Post JM, Keef KD, Hume JR. Intracellular divalent cations block smooth muscle K+ channels Circulation Research. 73: 24-34. PMID 7685253 DOI: 10.1161/01.Res.73.1.24 |
0.398 |
|
| 1993 |
Buxton IL, Cheek DJ, Eckman D, Westfall DP, Sanders KM, Keef KD. NG-nitro L-arginine methyl ester and other alkyl esters of arginine are muscarinic receptor antagonists. Circulation Research. 72: 387-95. PMID 7678206 DOI: 10.1161/01.Res.72.2.387 |
0.342 |
|
| 1993 |
Ishikawa T, Hume JR, Keef KD. Modulation of K+ and Ca2+ channels by histamine H1-receptor stimulation in rabbit coronary artery cells Journal of Physiology. 468: 379-400. PMID 7504729 DOI: 10.1113/Jphysiol.1993.Sp019777 |
0.4 |
|
| 1992 |
Eckman DM, Frankovich JD, Keef KD. Comparison of the actions of acetylcholine and BRL 38227 in the guinea‐pig coronary artery British Journal of Pharmacology. 106: 9-16. PMID 1504734 DOI: 10.1111/J.1476-5381.1992.Tb14285.X |
0.317 |
|
| 1992 |
Keef KD, Ward SM, Stevens RJ, Frey BW, Sanders KM. Electrical and mechanical effects of acetylcholine and substance P in subregions of canine colon American Journal of Physiology - Gastrointestinal and Liver Physiology. 262. PMID 1371648 DOI: 10.1152/Ajpgi.1992.262.2.G298 |
0.42 |
|
| 1992 |
Ward SM, Dalziel HH, Bradley ME, Buxton IL, Keef K, Westfall DP, Sanders KM. Involvement of cyclic GMP in non-adrenergic, non-cholinergic inhibitory neurotransmission in dog proximal colon. British Journal of Pharmacology. 107: 1075-82. PMID 1334749 DOI: 10.1111/J.1476-5381.1992.Tb13409.X |
0.474 |
|
| 1992 |
Zhang L, Keef KD, Bradley ME, Buxton ILO. Action of α(2A)-adrenergic receptors in circular smooth muscle of canine proximal colon American Journal of Physiology - Gastrointestinal and Liver Physiology. 262. PMID 1312795 DOI: 10.1152/Ajpgi.1992.262.3.G517 |
0.337 |
|
| 1991 |
Khoyi MA, Bowen SM, Keef KD. Effect of membrane potential on H1-receptor-mediated 45Ca influx in coronary artery. The American Journal of Physiology. 261: H554-60. PMID 1652214 DOI: 10.1152/Ajpheart.1991.261.2.H554 |
0.363 |
|
| 1990 |
Keef K, Frey B, Smith T. Direct actions of catecholamines on subsections of the canine colon wall Gastroenterology. 99: 1217. DOI: 10.1016/0016-5085(90)90726-H |
0.419 |
|
| 1989 |
Keef KD, Bowen SM. Effect of ACh on electrical and mechanical activity in guinea pig coronary arteries American Journal of Physiology - Heart and Circulatory Physiology. 257. PMID 2801972 DOI: 10.1152/Ajpheart.1989.257.4.H1096 |
0.348 |
|
| 1989 |
Leblanc N, Wilde DW, Keef KD, Hume JR. Electrophysiological mechanisms of minoxidil sulfate-induced vasodilation of rabbit portal vein Circulation Research. 65: 1102-1111. PMID 2791221 DOI: 10.1161/01.Res.65.4.1102 |
0.456 |
|
| 1985 |
Neild TO, Keef K. Measurements of the membrane potential of arterial smooth muscle in anesthetized animals and its relationship to changes in artery diameter. Microvascular Research. 30: 19-28. PMID 4021835 DOI: 10.1016/0026-2862(85)90034-2 |
0.307 |
|
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