| Year |
Citation |
Score |
| 2024 |
Barry ME, Rynkiewicz MJ, Pavadai E, Viana A, Lehman W, Moore JR. Glutamate 139 of tropomyosin is critical for cardiac thin filament blocked-state stabilization. Journal of Molecular and Cellular Cardiology. PMID 38266978 DOI: 10.1016/j.yjmcc.2024.01.004 |
0.467 |
|
| 2023 |
Lehman W, Rynkiewicz MJ. Troponin-I-induced tropomyosin pivoting defines thin-filament function in relaxed and active muscle. The Journal of General Physiology. 155. PMID 37249525 DOI: 10.1085/jgp.202313387 |
0.755 |
|
| 2023 |
Halder SS, Rynkiewicz MJ, Creso JG, Sewanan LR, Howland L, Moore JR, Lehman W, Campbell SG. Mechanisms of pathogenicity in the hypertrophic cardiomyopathy-associated TPM1 variant S215L. Pnas Nexus. 2: pgad011. PMID 36896133 DOI: 10.1093/pnasnexus/pgad011 |
0.679 |
|
| 2023 |
Doran MH, Rynkiewicz MJ, Rassici D, Bodt SML, Barry ME, Bullitt E, Yengo CM, Moore JR, Lehman W. Conformational changes linked to ADP release from human cardiac myosin bound to actin-tropomyosin. The Journal of General Physiology. 155. PMID 36633586 DOI: 10.1085/jgp.202213267 |
0.688 |
|
| 2022 |
Doran MH, Rynkiewicz MJ, Pavadai E, Bodt SML, Rasicci D, Moore JR, Yengo CM, Bullitt E, Lehman W. Myosin loop-4 is critical for optimal tropomyosin repositioning on actin during muscle activation and relaxation. The Journal of General Physiology. 155. PMID 36459134 DOI: 10.1085/jgp.202213274 |
0.854 |
|
| 2022 |
Rynkiewicz MJ, Pavadai E, Lehman W. Modeling Human Cardiac Thin Filament Structures. Frontiers in Physiology. 13: 932333. PMID 35812320 DOI: 10.3389/fphys.2022.932333 |
0.83 |
|
| 2022 |
Suphamungmee W, Lehman W, Morgan KG. Functional Remodeling of the Contractile Smooth Muscle Cell Cortex, a Provocative Concept, Supported by Direct Visualization of Cortical Remodeling. Biology. 11. PMID 35625390 DOI: 10.3390/biology11050662 |
0.345 |
|
| 2022 |
Pavadai E, Rynkiewicz MJ, Yang Z, Gould IR, Marston SB, Lehman W. Modulation of cardiac thin filament structure by phosphorylated troponin-I analyzed by protein-protein docking and molecular dynamics simulation. Archives of Biochemistry and Biophysics. 725: 109282. PMID 35577070 DOI: 10.1016/j.abb.2022.109282 |
0.852 |
|
| 2022 |
Teekakirikul P, Zhu W, Xu X, Young CB, Tan T, Smith AM, Wang C, Peterson KA, Gabriel GC, Ho S, Sheng Y, Moreau de Bellaing A, Sonnenberg DA, Lin JH, Fotiou E, ... ... Lehman WJ, et al. Genetic resiliency associated with dominant lethal mutation causing atrial septal defect with high heritability. Cell Reports. Medicine. 3: 100501. PMID 35243414 DOI: 10.1016/j.xcrm.2021.100501 |
0.634 |
|
| 2021 |
Doran MH, Lehman W. The Central Role of the F-Actin Surface in Myosin Force Generation. Biology. 10. PMID 34943138 DOI: 10.3390/biology10121221 |
0.527 |
|
| 2021 |
Sewanan LR, Park J, Rynkiewicz MJ, Racca AW, Papoutsidakis N, Schwan J, Jacoby DL, Moore JR, Lehman W, Qyang Y, Campbell SG. Loss of crossbridge inhibition drives pathological cardiac hypertrophy in patients harboring the TPM1 E192K mutation. The Journal of General Physiology. 153. PMID 34319370 DOI: 10.1085/jgp.202012640 |
0.669 |
|
| 2021 |
Lehman W, Pavadai E, Rynkiewicz MJ. C-terminal troponin-I residues trap tropomyosin in the muscle thin filament blocked-state. Biochemical and Biophysical Research Communications. 551: 27-32. PMID 33714756 DOI: 10.1016/j.bbrc.2021.03.010 |
0.844 |
|
| 2020 |
Racca AW, Rynkiewicz MJ, LaFave N, Ghosh A, Lehman W, Moore JR. M8R tropomyosin mutation disrupts actin-binding and filament regulation: the beginning affects the middle and end. The Journal of Biological Chemistry. PMID 33020181 DOI: 10.1074/jbc.RA120.014713 |
0.803 |
|
| 2020 |
Doran MH, Pavadai E, Rynkiewicz MJ, Walklate J, Bullitt E, Moore JR, Regnier M, Geeves MA, Lehman W. Cryo-EM and Molecular Docking Shows Myosin Loop 4 Contacts Actin and Tropomyosin on Thin Filaments. Biophysical Journal. PMID 32730789 DOI: 10.1016/J.Bpj.2020.07.006 |
0.871 |
|
| 2020 |
Pavadai E, Lehman W, Rynkiewicz MJ. Protein-Protein Docking Reveals Dynamic Interactions of Tropomyosin on Actin Filaments. Biophysical Journal. 119: 75-86. PMID 32521240 DOI: 10.1016/J.Bpj.2020.05.017 |
0.851 |
|
| 2020 |
Viswanathan MC, Schmidt W, Franz P, Rynkiewicz MJ, Newhard CS, Madan A, Lehman W, Swank DM, Preller M, Cammarato A. A role for actin flexibility in thin filament-mediated contractile regulation and myopathy. Nature Communications. 11: 2417. PMID 32415060 DOI: 10.1038/S41467-020-15922-5 |
0.842 |
|
| 2020 |
Pavadai E, Rynkiewicz MJ, Lehman W. A Tropomyosin Cable Model on Thin-Filaments Deduced by Protein-Protein Docking Biophysical Journal. 118. DOI: 10.1016/J.Bpj.2019.11.3205 |
0.783 |
|
| 2020 |
Doran M, Ghosh A, Lehman W, Bullitt E. Structure of the Actin-Tropomyosin-TNT Complex Biophysical Journal. 118: 7a-8a. DOI: 10.1016/J.Bpj.2019.11.233 |
0.606 |
|
| 2020 |
Rynkiewicz MJ, Lehman W. Molecular Dynamics Simulations of Alpha-Beta-Tropomyosin Show Conformational Properties of Heterodimeric Tropomyosin Biophysical Journal. 118. DOI: 10.1016/J.Bpj.2019.11.1598 |
0.614 |
|
| 2019 |
Sundar S, Rynkiewicz MJ, Ghosh A, Lehman W, Moore JR. Cardiomyopathy Mutation Alters End-to-End Junction of Tropomyosin and Reduces Calcium Sensitivity. Biophysical Journal. PMID 31882250 DOI: 10.1016/J.Bpj.2019.11.3396 |
0.82 |
|
| 2019 |
Lehman W, Maéda Y. Introducing a special issue of the Journal of Muscle Research and Cell Motility on actin and actin-binding proteins. Journal of Muscle Research and Cell Motility. PMID 31865487 DOI: 10.1007/S10974-019-09569-Z |
0.502 |
|
| 2019 |
Pavadai E, Rynkiewicz MJ, Ghosh A, Lehman W. Docking Troponin T onto the Tropomyosin Overlapping Domain of Thin Filaments. Biophysical Journal. PMID 31864661 DOI: 10.1016/J.Bpj.2019.11.3393 |
0.852 |
|
| 2019 |
Egge N, Arneaud SLB, Wales P, Mihelakis M, McClendon J, Fonseca RS, Savelle C, Gonzalez I, Ghorashi A, Yadavalli S, Lehman WJ, Mirzaei H, Douglas PM. Age-Onset Phosphorylation of a Minor Actin Variant Promotes Intestinal Barrier Dysfunction. Developmental Cell. 51: 587-601.e7. PMID 31794717 DOI: 10.1016/J.Devcel.2019.11.001 |
0.402 |
|
| 2019 |
Geeves MA, Lehrer SS, Lehman W. The mechanism of thin filament regulation: Models in conflict? The Journal of General Physiology. PMID 31570503 DOI: 10.1085/Jgp.201912446 |
0.44 |
|
| 2019 |
Janco M, Rynkiewicz MJ, Li L, Hook J, Eiffe E, Ghosh A, Böcking T, Lehman WJ, Hardeman EC, Gunning PW. Molecular integration of the anti-tropomyosin compound ATM-3507 into the coiled coil overlap region of the cancer-associated Tpm3.1. Scientific Reports. 9: 11262. PMID 31375704 DOI: 10.1038/S41598-019-47592-9 |
0.785 |
|
| 2019 |
Lehman W, Moore JR, Campbell SG, Rynkiewicz MJ. The Effect of Tropomyosin Mutations on Actin-Tropomyosin Binding: In Search of Lost Time. Biophysical Journal. PMID 31130236 DOI: 10.1016/J.Bpj.2019.05.009 |
0.782 |
|
| 2019 |
Lehman W, Rynkiewicz MJ, Moore JR. A new twist on tropomyosin binding to actin filaments: perspectives on thin filament function, assembly and biomechanics. Journal of Muscle Research and Cell Motility. PMID 30771202 DOI: 10.1007/S10974-019-09501-5 |
0.791 |
|
| 2019 |
Racca AW, LaFave N, Jones S, Rynkiewicz MJ, Lehman W, Moore JR. Functional Implications of Dcm End-to-End Bond Mutation in A-Tropomyosin Biophysical Journal. 116. DOI: 10.1016/J.Bpj.2018.11.989 |
0.621 |
|
| 2019 |
Rynkiewicz MJ, Moore JR, Campbell SG, Lehman W. A New Twist on the Mechanism of Mutation-Induced Tropomyosin Dysfunction Biophysical Journal. 116: 552a. DOI: 10.1016/J.Bpj.2018.11.2966 |
0.628 |
|
| 2019 |
Sundar S, Rynkiewicz MJ, Lehman W, Moore JR. Cardiomyopathy Mutation at End-End Overlap of Alpha - Tropomyosin Influences Cooperative Activation and Calcium Sensitivity Biophysical Journal. 116. DOI: 10.1016/J.Bpj.2018.11.2517 |
0.625 |
|
| 2019 |
Kiani FA, Lehman W, Fischer S, Rynkiewicz MJ. Tropomyosin Cable Formation and Its Influence on the Structural Dynamics of Tropomyosin Biophysical Journal. 116. DOI: 10.1016/J.Bpj.2018.11.199 |
0.787 |
|
| 2019 |
Ghosh A, Janco M, Böcking T, Gunning PW, Lehman W, Rynkiewicz MJ. Structure of the Tpm3.1 N-Terminus: A New Target for Anti-Cancer Treatment Biophysical Journal. 116: 253a-254a. DOI: 10.1016/J.Bpj.2018.11.1382 |
0.665 |
|
| 2018 |
Kiani FA, Lehman W, Fischer S, Rynkiewicz MJ. Spontaneous transitions of actin-bound tropomyosin toward blocked and closed states. The Journal of General Physiology. PMID 30442774 DOI: 10.1085/Jgp.201812188 |
0.849 |
|
| 2018 |
Lehman W, Li X, Kiani FA, Moore JR, Campbell SG, Fischer S, Rynkiewicz MJ. Precise Binding of Tropomyosin on Actin Involves Sequence-Dependent Variance in Coiled-Coil Twisting. Biophysical Journal. PMID 30195938 DOI: 10.1016/J.Bpj.2018.08.017 |
0.847 |
|
| 2018 |
Farman GP, Rynkiewicz MJ, Orzechowski M, Lehman W, Moore JR. HCM and DCM cardiomyopathy-linked α-tropomyosin mutations influence off-state stability and crossbridge interaction on thin filaments. Archives of Biochemistry and Biophysics. PMID 29626422 DOI: 10.1016/J.Abb.2018.04.002 |
0.844 |
|
| 2018 |
Kiani FA, Rynkiewicz MJ, Fischer S, Lehman W. Tropomyosin Translocation on F-Actin Revealed by Molecular Dynamics Simulations Biophysical Journal. 114. DOI: 10.1016/J.Bpj.2017.11.769 |
0.813 |
|
| 2018 |
Sewanan LR, Park J, Rynkiewicz MJ, Hollenberg SM, Papoutsidakis N, Jacoby DL, Moore JR, Lehman W, Qyang Y, Campbell SG. Pathogenic Mechanisms of the Cardiomyopathy-Associated Alpha-Tropomyosin Variant E192K as Revealed by Multiscale Modeling and Experiments Biophysical Journal. 114: 495a. DOI: 10.1016/J.Bpj.2017.11.2714 |
0.616 |
|
| 2018 |
Viswanathan MC, Schmidt W, Madan A, Sullivan LC, Newhard CS, Rynkiewicz MJ, Lehman W, Swank DM, Cammarato A. The ACTC M305L Hypertrophic Cardiomyopathy Mutation Results in Hypercontractility and Impaired Relaxation of Drosophila Muscles Biophysical Journal. 114: 315a. DOI: 10.1016/J.Bpj.2017.11.1776 |
0.765 |
|
| 2017 |
Rynkiewicz MJ, Prum T, Hollenberg S, Kiani FA, Fagnant PM, Marston SB, Trybus KM, Fischer S, Moore JR, Lehman W. Tropomyosin Must Interact Weakly with Actin to Effectively Regulate Thin Filament Function. Biophysical Journal. 113: 2444-2451. PMID 29211998 DOI: 10.1016/J.Bpj.2017.10.004 |
0.871 |
|
| 2017 |
Viswanathan MC, Schmidt W, Rynkiewicz MJ, Agarwal K, Gao J, Katz J, Lehman W, Cammarato A. Distortion of the Actin A-Triad Results in Contractile Disinhibition and Cardiomyopathy. Cell Reports. 20: 2612-2625. PMID 28903042 DOI: 10.1016/J.Celrep.2017.08.070 |
0.842 |
|
| 2017 |
Lehman W. Switching Muscles On and Off in Steps: The McKillop-Geeves Three-State Model of Muscle Regulation. Biophysical Journal. PMID 28552313 DOI: 10.1016/J.Bpj.2017.04.053 |
0.473 |
|
| 2017 |
Rynkiewicz M, Stehn J, Gunning P, Lehman W. Structure of the Anti-Cancer Compound TR100 Target-Sites on Tpm3.1 Tropomyosin Biophysical Journal. 112. DOI: 10.1016/J.Bpj.2016.11.3019 |
0.588 |
|
| 2017 |
Viswanathan MC, Schmidt W, Orzechowski M, Lehman W, Cammarato A. The Actc A295S Hypertrophic Cardiomyopathy Mutation Promotes Thin Filament Disinhibition and Enhances Contractile Activity Biophysical Journal. 112. DOI: 10.1016/J.Bpj.2016.11.3013 |
0.837 |
|
| 2017 |
Sewanan LR, Park J, Ren Y, Urdaneta A, Rynkiewicz M, Moore J, Lehman W, Jacoby DL, Qyang Y, Campbell SG. Investigating the Phenotype of Cardiomyopathy-Associated Alpha-Tropomyosin E192K Mutation in Patient-Derived Engineered Heart Tissue Biophysical Journal. 112: 260a. DOI: 10.1016/J.Bpj.2016.11.1412 |
0.604 |
|
| 2017 |
Moore JR, Prum T, Fagnant PM, Trybus KM, Lehman W. D292V Actin Mutation Stabilizes Tropomyosin in the Off-State of the Thin Filament Biophysical Journal. 112: 2-9. DOI: 10.1016/J.Bpj.2016.11.1409 |
0.461 |
|
| 2016 |
Sewanan LR, Moore JR, Lehman W, Campbell SG. Predicting Effects of Tropomyosin Mutations on Cardiac Muscle Contraction through Myofilament Modeling. Frontiers in Physiology. 7: 473. PMID 27833562 DOI: 10.3389/Fphys.2016.00473 |
0.427 |
|
| 2016 |
Rynkiewicz MJ, Fischer S, Lehman W. The propensity for tropomyosin twisting in the presence and absence of F-actin. Archives of Biochemistry and Biophysics. PMID 27663225 DOI: 10.1016/J.Abb.2016.09.008 |
0.775 |
|
| 2016 |
Lehman W. Thin Filament Structure and the Steric Blocking Model. Comprehensive Physiology. 6: 1043-69. PMID 27065174 DOI: 10.1002/Cphy.C150030 |
0.551 |
|
| 2016 |
Moore JR, Campbell SG, Lehman W. Structural determinants of muscle thin filament cooperativity. Archives of Biochemistry and Biophysics. 594: 8-17. PMID 26891592 DOI: 10.1016/J.Abb.2016.02.016 |
0.535 |
|
| 2016 |
Fischer S, Rynkiewicz MJ, Moore JR, Lehman W. Tropomyosin diffusion over actin subunits facilitates thin filament assembly. Structural Dynamics (Melville, N.Y.). 3: 012002. PMID 26798831 DOI: 10.1063/1.4940223 |
0.766 |
|
| 2016 |
Fischer S, Rynkiewicz MJ, Moore JR, Lehman W. Tropomyosin diffusion over actin subunits facilitates thin filament assembly Structural Dynamics. 3. DOI: 10.1063/1.4940223 |
0.67 |
|
| 2016 |
Ecken Jvd, Müller M, Lehman W, Manstein D, Penczek P, Raunser S. Structure of the F-Actin-Tropomyosin Complex Revealed by Electron Cryomicroscopy Biophysical Journal. 110. DOI: 10.1016/J.Bpj.2015.11.875 |
0.59 |
|
| 2016 |
Farman GP, Rynkiewicz M, Orzechowski M, Lehman W, Moore J. Cardiomyopathy Linked Mutations in Alpha Tropomyosin Influence Blocked State Stability but not Myosin Strong Binding Biophysical Journal. 110: 124a-125a. DOI: 10.1016/J.Bpj.2015.11.718 |
0.86 |
|
| 2016 |
Rynkiewicz M, Schott V, Orzechowski M, Fischer S, Lehman W. Does Tropomyosin Slide or Roll over F-Actin during Regulatory Transitions? Biophysical Journal. 110. DOI: 10.1016/J.Bpj.2015.11.2805 |
0.846 |
|
| 2016 |
Moore JR, Campbell SG, Lehman W. Structural determinants of muscle thin filament cooperativity Archives of Biochemistry and Biophysics. 594: 8-17. DOI: 10.1016/j.abb.2016.02.016 |
0.333 |
|
| 2015 |
Rynkiewicz MJ, Schott V, Orzechowski M, Lehman W, Fischer S. Electrostatic interaction map reveals a new binding position for tropomyosin on F-actin. Journal of Muscle Research and Cell Motility. 36: 525-33. PMID 26286845 DOI: 10.1007/S10974-015-9419-Z |
0.847 |
|
| 2015 |
Alamo L, Li XE, Espinoza-Fonseca LM, Pinto A, Thomas DD, Lehman W, Padrón R. Tarantula myosin free head regulatory light chain phosphorylation stiffens N-terminal extension, releasing it and blocking its docking back. Molecular Biosystems. 11: 2180-9. PMID 26038302 DOI: 10.1039/C5Mb00163C |
0.652 |
|
| 2015 |
Schmidt WM, Lehman W, Moore JR. Direct observation of tropomyosin binding to actin filaments. Cytoskeleton (Hoboken, N.J.). PMID 26033920 DOI: 10.1002/Cm.21225 |
0.568 |
|
| 2015 |
Begonja AJ, Pluthero FG, Suphamungmee W, Giannini S, Christensen H, Leung R, Lo RW, Nakamura F, Lehman W, Plomann M, Hoffmeister KM, Kahr WH, Hartwig JH, Falet H. FlnA binding to PACSIN2 F-BAR domain regulates membrane tubulation in megakaryocytes and platelets. Blood. 126: 80-8. PMID 25838348 DOI: 10.1182/Blood-2014-07-587600 |
0.322 |
|
| 2015 |
Lehman W, Medlock G, Li XE, Suphamungmee W, Tu AY, Schmidtmann A, Ujfalusi Z, Fischer S, Moore JR, Geeves MA, Regnier M. Phosphorylation of Ser283 enhances the stiffness of the tropomyosin head-to-tail overlap domain. Archives of Biochemistry and Biophysics. 571: 10-5. PMID 25726728 DOI: 10.1016/J.Abb.2015.02.026 |
0.699 |
|
| 2015 |
von der Ecken J, Müller M, Lehman W, Manstein DJ, Penczek PA, Raunser S. Structure of the F-actin-tropomyosin complex. Nature. 519: 114-7. PMID 25470062 DOI: 10.1038/Nature14033 |
0.588 |
|
| 2014 |
Orzechowski M, Fischer S, Moore JR, Lehman W, Farman GP. Energy landscapes reveal the myopathic effects of tropomyosin mutations. Archives of Biochemistry and Biophysics. 564: 89-99. PMID 25241052 DOI: 10.1016/J.Abb.2014.09.007 |
0.804 |
|
| 2014 |
Orzechowski M, Li XE, Fischer S, Lehman W. An atomic model of the tropomyosin cable on F-actin. Biophysical Journal. 107: 694-9. PMID 25099808 DOI: 10.1016/J.Bpj.2014.06.034 |
0.853 |
|
| 2014 |
Gu C, Chang J, Shchedrina VA, Pham VA, Hartwig JH, Suphamungmee W, Lehman W, Hyman BT, Bacskai BJ, Sever S. Regulation of dynamin oligomerization in cells: the role of dynamin-actin interactions and its GTPase activity. Traffic (Copenhagen, Denmark). 15: 819-38. PMID 24891099 DOI: 10.1111/Tra.12178 |
0.456 |
|
| 2014 |
Li XE, Orzechowski M, Lehman W, Fischer S. Structure and flexibility of the tropomyosin overlap junction. Biochemical and Biophysical Research Communications. 446: 304-8. PMID 24607906 DOI: 10.1016/J.Bbrc.2014.02.097 |
0.84 |
|
| 2014 |
Yang S, Barbu-Tudoran L, Orzechowski M, Craig R, Trinick J, White H, Lehman W. Three-dimensional organization of troponin on cardiac muscle thin filaments in the relaxed state. Biophysical Journal. 106: 855-64. PMID 24559988 DOI: 10.1016/J.Bpj.2014.01.007 |
0.812 |
|
| 2014 |
Orzechowski M, Moore JR, Fischer S, Lehman W. Tropomyosin movement on F-actin during muscle activation explained by energy landscapes Archives of Biochemistry and Biophysics. 545: 63-68. PMID 24412204 DOI: 10.1016/J.Abb.2014.01.001 |
0.801 |
|
| 2014 |
Viswanathan MC, Kaushik G, Engler AJ, Lehman W, Cammarato A. A Drosophila melanogaster model of diastolic dysfunction and cardiomyopathy based on impaired troponin-T function. Circulation Research. 114: e6-17. PMID 24221941 DOI: 10.1161/Circresaha.114.302028 |
0.718 |
|
| 2014 |
Lehman W, Li XE, Orzechowski M, Fischer S. The structural dynamics of α-tropomyosin on F-actin shape the overlap complex between adjacent tropomyosin molecules. Archives of Biochemistry and Biophysics. 552: 68-73. PMID 24071513 DOI: 10.1016/J.Abb.2013.09.011 |
0.841 |
|
| 2014 |
Schmidt WM, Wang A, Leavis P, Lehman W, Moore JR. Direct Visualization of Tropomyosin Isoform Binding to F-Actin Biophysical Journal. 106. DOI: 10.1016/J.Bpj.2013.11.940 |
0.554 |
|
| 2014 |
Lehman W, Li X, Orzechowski M, Fischer S. The Structural Dynamics of Alpha-Tropomyosin on F-Actin Shape the Overlap Complex between Adjacent Tropomyosin Molecules Biophysical Journal. 106: 7-9. DOI: 10.1016/J.Bpj.2013.11.4223 |
0.823 |
|
| 2014 |
Medlock G, Suphamungmee W, Tu A, Li X(, Regnier M, Geeves MA, Lehman W. Effects of Phosphomimetic Mutations on the Persistence Length and Thin Filament Binding Properties of α and β-Tropomyosin Biophysical Journal. 106: 252a. DOI: 10.1016/J.Bpj.2013.11.1485 |
0.676 |
|
| 2014 |
Orzechowski M, Fischer S, Moore JR, Lehman W, Farman GP. Energy landscapes reveal the myopathic effects of tropomyosin mutations Archives of Biochemistry and Biophysics. 564: 89-99. DOI: 10.1016/j.abb.2014.09.007 |
0.672 |
|
| 2013 |
Marston S, Memo M, Messer A, Papadaki M, Nowak K, Mcnamara E, Ong R, El-Mezgueldi M, Li X, Lehman W. Mutations in repeating structural motifs of tropomyosin cause gain of function in skeletal muscle myopathy patients Human Molecular Genetics. 22: 4978-4987. PMID 23886664 DOI: 10.1093/Hmg/Ddt345 |
0.611 |
|
| 2013 |
Janco M, Suphamungmee W, Li X, Lehman W, Lehrer SS, Geeves MA. Polymorphism in tropomyosin structure and function. Journal of Muscle Research and Cell Motility. 34: 177-87. PMID 23832280 DOI: 10.1007/S10974-013-9353-X |
0.631 |
|
| 2013 |
Lehman W, Orzechowski M, Li XE, Fischer S, Raunser S. Gestalt-binding of tropomyosin on actin during thin filament activation. Journal of Muscle Research and Cell Motility. 34: 155-63. PMID 23666668 DOI: 10.1007/S10974-013-9342-0 |
0.852 |
|
| 2013 |
Marston SB, Lehman W, Li X, Memo M. A Repeating Structural Motif in Tropomyosin that is Responsible for Multiple Gain of Function Skeletal Myopathy Mutations Biophysical Journal. 104: 646a-647a. DOI: 10.1016/J.Bpj.2012.11.3571 |
0.633 |
|
| 2013 |
Suphamungmee W, Li X(, Janco M, Geeves MA, Lehman W. Persistence Length of Tropomyosin Heterodimers Formed from Wild-Type and Mutant Chains Biophysical Journal. 104: 481a. DOI: 10.1016/J.Bpj.2012.11.2657 |
0.568 |
|
| 2013 |
Li X(, Orzechowski M, Fischer S, Lehman W. Tropomyosin Flexibility and Transitions between Thin Filament On- and Off-States Biophysical Journal. 104. DOI: 10.1016/J.Bpj.2012.11.2656 |
0.851 |
|
| 2013 |
Orzechowski M, Fischer S, Lehman W. Influence of Actin Mutation on the Energy Landscape of Actin-Tropomyosin Filaments Biophysical Journal. 104. DOI: 10.1016/J.Bpj.2012.11.2654 |
0.779 |
|
| 2013 |
Yang S, Barbu-Tudoran L, Orzechowski M, Craig R, Trinick J, Lehman W, White H. 3D-Reconstruction Reveals the Organization of Troponin on Cardiac Thin Filaments Biophysical Journal. 104: 453a. DOI: 10.1016/J.Bpj.2012.11.2509 |
0.788 |
|
| 2013 |
Viswanathan MC, Lehman W, Cammarato A. A Troponin-T Mutation Initiates Cardiac and Skeletal Myopathy due to Impaired Inhibition of Contraction in Drosophila Melanogaster Biophysical Journal. 104. DOI: 10.1016/J.Bpj.2012.11.1727 |
0.761 |
|
| 2012 |
Suphamungmee W, Nakamura F, Hartwig JH, Lehman W. Electron microscopy and 3D reconstruction reveals filamin Ig domain binding to F-actin. Journal of Molecular Biology. 424: 248-56. PMID 23041423 DOI: 10.1016/J.Jmb.2012.09.025 |
0.528 |
|
| 2012 |
Li XE, Suphamungmee W, Janco M, Geeves MA, Marston SB, Fischer S, Lehman W. The flexibility of two tropomyosin mutants, D175N and E180G, that cause hypertrophic cardiomyopathy Biochemical and Biophysical Research Communications. 424: 493-496. PMID 22789852 DOI: 10.1016/J.Bbrc.2012.06.141 |
0.734 |
|
| 2012 |
Lehman W, Morgan KG. Structure and dynamics of the actin-based smooth muscle contractile and cytoskeletal apparatus. Journal of Muscle Research and Cell Motility. 33: 461-9. PMID 22311558 DOI: 10.1007/S10974-012-9283-Z |
0.484 |
|
| 2012 |
Jensen MH, Watt J, Hodgkinson JL, Gallant C, Appel S, El-Mezgueldi M, Angelini TE, Morgan KG, Lehman W, Moore JR. Effects of basic calponin on the flexural mechanics and stability of F-actin. Cytoskeleton (Hoboken, N.J.). 69: 49-58. PMID 22135101 DOI: 10.1002/Cm.20548 |
0.863 |
|
| 2012 |
Rao JN, Rivera-Santiago R, Li XE, Lehman W, Dominguez R. Structural analysis of smooth muscle tropomyosin α and β isoforms. The Journal of Biological Chemistry. 287: 3165-74. PMID 22119916 DOI: 10.1074/Jbc.M111.307330 |
0.708 |
|
| 2012 |
Li X, Lehman W, Fischer S. Geometry of the C-/N-Terminal Connection of Tropomyosin on F-Actin Based on Molecular Dynamics Simulations of the Thin Filament Biophysical Journal. 102. DOI: 10.1016/J.Bpj.2011.11.847 |
0.692 |
|
| 2012 |
Jampani NR, Rivera-Saniago R, Li X(, Lehman W, Dominguez R. Structural analysis of smooth muscle tropomyosin alpha and beta isoforms Journal of Biological Chemistry. 287: 3165-3174. DOI: 10.1016/J.Bpj.2011.11.2047 |
0.709 |
|
| 2012 |
Yang S, Barbu-Tudoran L, Craig R, Trinick J, Lehman W, White H. Visualization of Troponin on Muscle Thin Filaments by Single Particle Analysis Biophysical Journal. 102: 229a. DOI: 10.1016/J.Bpj.2011.11.1260 |
0.548 |
|
| 2012 |
Orzechowski M, Raunser S, Fischer S, Lehman W. Tropomyosin Movement on F-actin Analyzed by Energy Landscape Determination Biophysical Journal. 102. DOI: 10.1016/J.Bpj.2011.11.115 |
0.811 |
|
| 2011 |
Moore JR, Li X, Nirody J, Fischer S, Lehman W. Structural implications of conserved aspartate residues located in tropomyosin's coiled-coil core. Bioarchitecture. 1: 250-255. PMID 22754618 DOI: 10.4161/bioa.18117 |
0.819 |
|
| 2011 |
Cammarato A, Li XE, Reedy MC, Lee CF, Lehman W, Bernstein SI. Structural basis for myopathic defects engendered by alterations in the myosin rod. Journal of Molecular Biology. 414: 477-84. PMID 22037585 DOI: 10.1016/J.Jmb.2011.10.019 |
0.749 |
|
| 2011 |
Collins A, Huang R, Jensen MH, Moore JR, Lehman W, Wang CL. Structural studies on maturing actin filaments. Bioarchitecture. 1: 127-133. PMID 21922043 DOI: 10.4161/bioa.1.3.16714 |
0.673 |
|
| 2011 |
East DA, Sousa D, Martin SR, Edwards TA, Lehman W, Mulvihill DP. Altering the stability of the Cdc8 overlap region modulates the ability of this tropomyosin to bind co-operatively to actin and regulate myosin. The Biochemical Journal. 438: 265-73. PMID 21658004 DOI: 10.1042/Bj20101316 |
0.797 |
|
| 2011 |
Mun JY, Gulick J, Robbins J, Woodhead J, Lehman W, Craig R. Electron microscopy and 3D reconstruction of F-actin decorated with cardiac myosin-binding protein C (cMyBP-C). Journal of Molecular Biology. 410: 214-25. PMID 21601575 DOI: 10.1016/J.Jmb.2011.05.010 |
0.537 |
|
| 2011 |
Li XE, Tobacman LS, Mun JY, Craig R, Fischer S, Lehman W. Tropomyosin position on F-actin revealed by EM reconstruction and computational chemistry. Biophysical Journal. 100: 1005-13. PMID 21320445 DOI: 10.1016/J.Bpj.2010.12.3697 |
0.679 |
|
| 2011 |
Gallant C, Appel S, Graceffa P, Leavis P, Lin JJ, Gunning PW, Schevzov G, Chaponnier C, DeGnore J, Lehman W, Morgan KG. Tropomyosin variants describe distinct functional subcellular domains in differentiated vascular smooth muscle cells. American Journal of Physiology. Cell Physiology. 300: C1356-65. PMID 21289288 DOI: 10.1152/Ajpcell.00450.2010 |
0.397 |
|
| 2011 |
Li XE, Fischer S, Lehman W. Molecular Dynamics of Tropomyosin Bound to F-Actin Biophysical Journal. 100. DOI: 10.1016/J.Bpj.2010.12.3387 |
0.684 |
|
| 2011 |
Orzechowski M, Fischer S, Lehman W. Structural Simulations of Troponin-Regulated Tropomyosin Movement on F-Actin Biophysical Journal. 100: 5-6. DOI: 10.1016/J.Bpj.2010.12.3386 |
0.833 |
|
| 2011 |
Li XE, Tobacman LS, Mun JY, Craig R, Fischer S, Lehman W. Atomic Model of F-Actin-Tropomyosin Biophysical Journal. 100: 586a. DOI: 10.1016/J.Bpj.2010.12.3385 |
0.716 |
|
| 2011 |
Schmidt WM, Leavis P, Lehman W, Moore J. Monitoring the Real-Time Binding of Tropomyosin to Actin using Total Internal Reflection Fluorescence Microscopy Biophysical Journal. 100. DOI: 10.1016/J.Bpj.2010.12.1849 |
0.595 |
|
| 2010 |
Coulton AT, East DA, Galinska-Rakoczy A, Lehman W, Mulvihill DP. The recruitment of acetylated and unacetylated tropomyosin to distinct actin polymers permits the discrete regulation of specific myosins in fission yeast. Journal of Cell Science. 123: 3235-43. PMID 20807799 DOI: 10.1242/Jcs.069971 |
0.545 |
|
| 2010 |
Sousa D, Cammarato A, Jang K, Graceffa P, Tobacman LS, Li XE, Lehman W. Electron microscopy and persistence length analysis of semi-rigid smooth muscle tropomyosin strands. Biophysical Journal. 99: 862-8. PMID 20682264 DOI: 10.1016/J.Bpj.2010.05.004 |
0.84 |
|
| 2010 |
Li XE, Lehman W, Fischer S. The relationship between curvature, flexibility and persistence length in the tropomyosin coiled-coil. Journal of Structural Biology. 170: 313-8. PMID 20117217 DOI: 10.1016/J.Jsb.2010.01.016 |
0.623 |
|
| 2010 |
Galińska A, Hatch V, Craig R, Murphy AM, Van Eyk JE, Wang CL, Lehman W, Foster DB. The C terminus of cardiac troponin I stabilizes the Ca2+-activated state of tropomyosin on actin filaments. Circulation Research. 106: 705-11. PMID 20035081 DOI: 10.1161/Circresaha.109.210047 |
0.598 |
|
| 2010 |
Li XE, Lehman W, Fischer S, Holmes KC. Curvature variation along the tropomyosin molecule. Journal of Structural Biology. 170: 307-12. PMID 20026408 DOI: 10.1016/J.Jsb.2009.12.017 |
0.724 |
|
| 2010 |
Cammarato A, Craig R, Lehman W. Electron microscopy and three-dimensional reconstruction of native thin filaments reveal species-specific differences in regulatory strand densities. Biochemical and Biophysical Research Communications. 391: 193-7. PMID 19900412 DOI: 10.1016/J.Bbrc.2009.11.030 |
0.714 |
|
| 2010 |
Li XE, Holmes KC, Lehman W, Jung H, Fischer S. The shape and flexibility of tropomyosin coiled coils: implications for actin filament assembly and regulation. Journal of Molecular Biology. 395: 327-39. PMID 19883661 DOI: 10.1016/J.Jmb.2009.10.060 |
0.817 |
|
| 2010 |
East D, Sousa D, Lehman W, Mulvihill DP. Precise Modulation of Tropomyosin Polymer Length is Crucial for its Association with Actin and Ability to Regulate Myosin Function Biophysical Journal. 98. DOI: 10.1016/J.Bpj.2009.12.841 |
0.792 |
|
| 2010 |
Cammarato A, Li X, Reedy MC, Lee C, Li P, Lehman W, Bernstein SI. Transgenic Replacement of the Myosin S2/hmm Hinge Alters the Rod's Nano-Mechanical Properties and Affects Sarcomeric Organization Biophysical Journal. 98: 543a. DOI: 10.1016/J.Bpj.2009.12.2946 |
0.768 |
|
| 2010 |
Sousa D, Cammarato A, Li J, Li X, Lehman W. Smooth Muscle Tropomyosin Forms Semi-Rigid End to End Polymers Biophysical Journal. 98. DOI: 10.1016/J.Bpj.2009.12.2940 |
0.85 |
|
| 2010 |
Nirody J, Li X, Sousa D, Sumida J, Fischer S, Lehrer SS, Lehman W. Electron Microscopy and Molecular Dynamics on a D137L Mutant of Tropomyosin Biophysical Journal. 98: 414a. DOI: 10.1016/J.Bpj.2009.12.2238 |
0.83 |
|
| 2010 |
Jung HS, Sousa D, Tobacman LS, Craig R, Lehman W. Em and Single Particle Analysis of Troponin at Low and High Ca2+ Biophysical Journal. 98: 353a. DOI: 10.1016/J.Bpj.2009.12.1907 |
0.764 |
|
| 2009 |
Lehman W, Galińska-Rakoczy A, Hatch V, Tobacman LS, Craig R. Structural basis for the activation of muscle contraction by troponin and tropomyosin. Journal of Molecular Biology. 388: 673-81. PMID 19341744 DOI: 10.1016/J.Jmb.2009.03.060 |
0.559 |
|
| 2009 |
Facemyer KC, Dominguez R, Cremo CR, Lehman WJ. Computational Analysis of the Interaction Between Paired CH-Domains - Implications for their F-actin Bound Conformations Biophysical Journal. 96: 126a. DOI: 10.1016/J.Bpj.2008.12.564 |
0.445 |
|
| 2009 |
Paul DM, Lehman W, Pirani A, Craig R, Tobacman LS, Squire JM, Morris EP. Reference Free Single Particle Analysis Of Reconstituted Thin Filaments Biophysical Journal. 96: 376a. DOI: 10.1016/J.Bpj.2008.12.2824 |
0.83 |
|
| 2009 |
Galinska-Rakoczy A, Hatch V, Craig R, Murphy AM, Van Eyk JE, Wang CA, Lehman W, Foster DB. EM and 3D-Reconstruction of Thin Filaments Reconstituted with Truncated Troponin I Associated with Myocardial Stunning Biophysical Journal. 96: 502a. DOI: 10.1016/J.Bpj.2008.12.2588 |
0.576 |
|
| 2009 |
Sousa D, Li X, Singh A, Jung H, Tobacman L, Craig R, Hitchcock-DeGregori S, Lehman W. Tropomyosin Flexibility Evaluated by Electron Microscopy Image Analysis Biophysical Journal. 96: 231a. DOI: 10.1016/J.Bpj.2008.12.1135 |
0.833 |
|
| 2009 |
Li X, Lehman W, Holmes KC, Fischer S. Molecular Dynamics of Tropomyosin: Implications for the Assembly and Regulation of Thin Filaments Biophysical Journal. 96: 201a. DOI: 10.1016/J.Bpj.2008.12.1082 |
0.802 |
|
| 2008 |
Lehman W, Craig R. Tropomyosin and the steric mechanism of muscle regulation. Advances in Experimental Medicine and Biology. 644: 95-109. PMID 19209816 DOI: 10.1007/978-0-387-85766-4_8 |
0.52 |
|
| 2008 |
Holmes KC, Lehman W. Gestalt-binding of tropomyosin to actin filaments. Journal of Muscle Research and Cell Motility. 29: 213-9. PMID 19116763 DOI: 10.1007/S10974-008-9157-6 |
0.726 |
|
| 2008 |
Galińska-Rakoczy A, Engel P, Xu C, Jung H, Craig R, Tobacman LS, Lehman W. Structural basis for the regulation of muscle contraction by troponin and tropomyosin. Journal of Molecular Biology. 379: 929-35. PMID 18514658 DOI: 10.1016/j.jmb.2008.04.062 |
0.613 |
|
| 2008 |
Maytum R, Hatch V, Konrad M, Lehman W, Geeves MA. Ultra short yeast tropomyosins show novel myosin regulation. The Journal of Biological Chemistry. 283: 1902-10. PMID 18006493 DOI: 10.1074/Jbc.M708593200 |
0.509 |
|
| 2008 |
Greenberg MJ, Wang CL, Lehman W, Moore JR. Modulation of actin mechanics by caldesmon and tropomyosin. Cell Motility and the Cytoskeleton. 65: 156-64. PMID 18000881 DOI: 10.1002/Cm.20251 |
0.607 |
|
| 2007 |
Skoumpla K, Coulton AT, Lehman W, Geeves MA, Mulvihill DP. Acetylation regulates tropomyosin function in the fission yeast Schizosaccharomyces pombe. Journal of Cell Science. 120: 1635-45. PMID 17452625 DOI: 10.1242/Jcs.001115 |
0.556 |
|
| 2006 |
Poole KJ, Lorenz M, Evans G, Rosenbaum G, Pirani A, Craig R, Tobacman LS, Lehman W, Holmes KC. A comparison of muscle thin filament models obtained from electron microscopy reconstructions and low-angle X-ray fibre diagrams from non-overlap muscle. Journal of Structural Biology. 155: 273-84. PMID 16793285 DOI: 10.1016/J.Jsb.2006.02.020 |
0.845 |
|
| 2006 |
Pant K, Chereau D, Hatch V, Dominguez R, Lehman W. Cortactin binding to F-actin revealed by electron microscopy and 3D reconstruction. Journal of Molecular Biology. 359: 840-7. PMID 16697006 DOI: 10.1016/J.Jmb.2006.03.065 |
0.858 |
|
| 2006 |
Pirani A, Vinogradova MV, Curmi PM, King WA, Fletterick RJ, Craig R, Tobacman LS, Xu C, Hatch V, Lehman W. An atomic model of the thin filament in the relaxed and Ca2+-activated states. Journal of Molecular Biology. 357: 707-17. PMID 16469331 DOI: 10.1016/J.Jmb.2005.12.050 |
0.847 |
|
| 2005 |
Cammarato A, Craig R, Sparrow JC, Lehman W. E93K charge reversal on actin perturbs steric regulation of thin filaments. Journal of Molecular Biology. 347: 889-94. PMID 15784249 DOI: 10.1016/J.Jmb.2005.02.022 |
0.743 |
|
| 2005 |
Pirani A, Xu C, Hatch V, Craig R, Tobacman LS, Lehman W. Single particle analysis of relaxed and activated muscle thin filaments. Journal of Molecular Biology. 346: 761-72. PMID 15713461 DOI: 10.1016/J.Jmb.2004.12.013 |
0.805 |
|
| 2005 |
Gong H, Hatch V, Ali L, Lehman W, Craig R, Tobacman LS. Mini-thin filaments regulated by troponin-tropomyosin. Proceedings of the National Academy of Sciences of the United States of America. 102: 656-61. PMID 15644437 DOI: 10.1073/Pnas.0407225102 |
0.536 |
|
| 2004 |
Lehman W, Craig R. The structure of the vertebrate striated muscle thin filament: a tribute to the contributions of Jean Hanson. Journal of Muscle Research and Cell Motility. 25: 455-66. PMID 15630610 DOI: 10.1007/S10974-004-3148-Z |
0.461 |
|
| 2004 |
Lehman W, Craig R, Kendrick-Jones J, Sutherland-Smith AJ. An open or closed case for the conformation of calponin homology domains on F-actin? Journal of Muscle Research and Cell Motility. 25: 351-8. PMID 15548864 DOI: 10.1007/S10974-004-0690-7 |
0.681 |
|
| 2004 |
Foster DB, Huang R, Hatch V, Craig R, Graceffa P, Lehman W, Wang CL. Modes of caldesmon binding to actin: sites of caldesmon contact and modulation of interactions by phosphorylation. The Journal of Biological Chemistry. 279: 53387-94. PMID 15456752 DOI: 10.1074/Jbc.M410109200 |
0.675 |
|
| 2004 |
Cammarato A, Hatch V, Saide J, Craig R, Sparrow JC, Tobacman LS, Lehman W. Drosophila muscle regulation characterized by electron microscopy and three-dimensional reconstruction of thin filament mutants. Biophysical Journal. 86: 1618-24. PMID 14990488 DOI: 10.1016/S0006-3495(04)74229-0 |
0.74 |
|
| 2003 |
Sutherland-Smith AJ, Moores CA, Norwood FL, Hatch V, Craig R, Kendrick-Jones J, Lehman W. An atomic model for actin binding by the CH domains and spectrin-repeat modules of utrophin and dystrophin. Journal of Molecular Biology. 329: 15-33. PMID 12742015 DOI: 10.1016/S0022-2836(03)00422-4 |
0.615 |
|
| 2002 |
Tobacman LS, Nihli M, Butters C, Heller M, Hatch V, Craig R, Lehman W, Homsher E. The troponin tail domain promotes a conformational state of the thin filament that suppresses myosin activity. The Journal of Biological Chemistry. 277: 27636-42. PMID 12011043 DOI: 10.1074/Jbc.M201768200 |
0.527 |
|
| 2002 |
Craig R, Lehman W. The ultrastructural basis of actin filament regulation. Results and Problems in Cell Differentiation. 36: 149-69. PMID 11892278 DOI: 10.1007/978-3-540-46558-4_12 |
0.545 |
|
| 2001 |
Craig R, Lehman W. Crossbridge and tropomyosin positions observed in native, interacting thick and thin filaments. Journal of Molecular Biology. 311: 1027-36. PMID 11531337 DOI: 10.1006/Jmbi.2001.4897 |
0.567 |
|
| 2001 |
Hatch V, Zhi G, Smith L, Stull JT, Craig R, Lehman W. Myosin light chain kinase binding to a unique site on F-actin revealed by three-dimensional image reconstruction. The Journal of Cell Biology. 154: 611-7. PMID 11481347 DOI: 10.1083/Jcb.200105079 |
0.568 |
|
| 2001 |
Lehman W, Rosol M, Tobacman LS, Craig R. Troponin organization on relaxed and activated thin filaments revealed by electron microscopy and three-dimensional reconstruction Journal of Molecular Biology. 307: 739-744. PMID 11273697 DOI: 10.1006/Jmbi.2001.4514 |
0.831 |
|
| 2001 |
Burhop J, Rosol M, Craig R, Tobacman LS, Lehman W. Effects of a Cardiomyopathy-causing Troponin T Mutation on Thin Filament Function and Structure Journal of Biological Chemistry. 276: 20788-20794. PMID 11262409 DOI: 10.1074/Jbc.M101110200 |
0.821 |
|
| 2000 |
Lehman W, Hatch V, Korman V, Rosol M, Thomas L, Maytum R, Geeves MA, Van Eyk JE, Tobacman LS, Craig R. Tropomyosin and actin isoforms modulate the localization of tropomyosin strands on actin filaments. Journal of Molecular Biology. 302: 593-606. PMID 10986121 DOI: 10.1006/Jmbi.2000.4080 |
0.855 |
|
| 2000 |
Korman VL, Hatch V, Dixon KY, Craig R, Lehman W, Tobacman LS. An actin subdomain 2 mutation that impairs thin filament regulation by troponin and tropomyosin. The Journal of Biological Chemistry. 275: 22470-8. PMID 10801864 DOI: 10.1074/Jbc.M002939200 |
0.622 |
|
| 2000 |
Rosol M, Lehman W, Craig R, Landis C, Butters C, Tobacman LS. Three-dimensional reconstruction of thin filaments containing mutant tropomyosin. Biophysical Journal. 78: 908-17. PMID 10653803 DOI: 10.1016/S0006-3495(00)76648-3 |
0.823 |
|
| 2000 |
Lehman W, Hatch V, Rosol M, Korman V, Horowitz R, Eyk JV, Tobacman LS, Craig R. Troponin-Tropomyosin Control of Thin Filament Activity Revealed by Electron Microscopy and 3-D Reconstruction. Microscopy and Microanalysis. 6: 88-89. DOI: 10.1017/S1431927600032931 |
0.746 |
|
| 1999 |
Xu C, Craig R, Tobacman L, Horowitz R, Lehman W. Tropomyosin positions in regulated thin filaments revealed by cryoelectron microscopy. Biophysical Journal. 77: 985-92. PMID 10423443 DOI: 10.1016/S0006-3495(99)76949-3 |
0.573 |
|
| 1998 |
Hanein D, Volkmann N, Goldsmith S, Michon AM, Lehman W, Craig R, DeRosier D, Almo S, Matsudaira P. An atomic model of fimbrin binding to F-actin and its implications for filament crosslinking and regulation Nature Structural Biology. 5: 787-792. PMID 9731773 DOI: 10.1038/1828 |
0.491 |
|
| 1997 |
Lehman W, Vibert P, Craig R. Visualization of caldesmon on smooth muscle thin filaments. Journal of Molecular Biology. 274: 310-7. PMID 9405141 DOI: 10.1006/Jmbi.1997.1422 |
0.587 |
|
| 1997 |
Hodgkinson JL, EL-Mezgueldi M, Craig R, Vibert P, Marston SB, Lehman W. 3-D image reconstruction of reconstituted smooth muscle thin filaments containing calponin: Visualization of interactions between F-actin and calponin Journal of Molecular Biology. 273: 150-159. PMID 9367753 DOI: 10.1006/Jmbi.1997.1307 |
0.566 |
|
| 1997 |
Hodgkinson JL, Marston SB, Craig R, Vibert P, Lehman W. Three-dimensional image reconstruction of reconstituted smooth muscle thin filaments: Effects of caldesmon Biophysical Journal. 72: 2398-2404. PMID 9168017 DOI: 10.1016/S0006-3495(97)78885-4 |
0.551 |
|
| 1997 |
Vibert P, Craig R, Lehman W. Steric-model for activation of muscle thin filaments. Journal of Molecular Biology. 266: 8-14. PMID 9054965 DOI: 10.1006/Jmbi.1996.0800 |
0.569 |
|
| 1995 |
Lehman W, Vibert P, Uman P, Craig R. Steric-blocking by tropomyosin visualized in relaxed vertebrate muscle thin filaments. Journal of Molecular Biology. 251: 191-6. PMID 7643394 DOI: 10.1006/Jmbi.1995.0425 |
0.54 |
|
| 1994 |
Lehman W, Craig R, Vibert P. Ca(2+)-induced tropomyosin movement in Limulus thin filaments revealed by three-dimensional reconstruction. Nature. 368: 65-7. PMID 8107884 DOI: 10.1038/368065A0 |
0.515 |
|
| 1993 |
Vibert P, Craig R, Lehman W. Three-dimensional reconstruction of caldesmon-containing smooth muscle thin filaments. The Journal of Cell Biology. 123: 313-21. PMID 8408215 DOI: 10.1083/Jcb.123.2.313 |
0.566 |
|
| 1993 |
Graceffa P, Adam LP, Lehman W. Disulphide cross-linking of smooth-muscle and non-muscle caldesmon to the C-terminus of actin in reconstituted and native thin filaments. The Biochemical Journal. 294: 63-7. PMID 8363587 DOI: 10.1042/Bj2940063 |
0.513 |
|
| 1993 |
Lehman W, Denault D, Marston S. The caldesmon content of vertebrate smooth muscle. Biochimica Et Biophysica Acta. 1203: 53-9. PMID 8218392 DOI: 10.1016/0167-4838(93)90035-P |
0.414 |
|
| 1991 |
Lehman W. Calponin and the composition of smooth muscle thin filaments. Journal of Muscle Research and Cell Motility. 12: 221-4. PMID 1874963 DOI: 10.1007/Bf01745110 |
0.543 |
|
| 1990 |
Moody C, Lehman W, Craig R. Caldesmon and the structure of smooth muscle thin filaments: electron microscopy of isolated thin filaments. Journal of Muscle Research and Cell Motility. 11: 176-85. PMID 2351755 DOI: 10.1007/Bf01766496 |
0.559 |
|
| 1990 |
Lehman W, Moody C, Craig R. Caldesmon and the structure of vertebrate smooth muscle thin filaments. A minireview. Annals of the New York Academy of Sciences. 599: 75-84. PMID 2221678 DOI: 10.1111/J.1749-6632.1990.Tb42366.X |
0.446 |
|
| 1989 |
Lehman W, Craig R, Lui J, Moody C. Caldesmon and the structure of smooth muscle thin filaments: immunolocalization of caldesmon on thin filaments. Journal of Muscle Research and Cell Motility. 10: 101-12. PMID 2760189 DOI: 10.1007/Bf01739966 |
0.453 |
|
| 1989 |
Babu A, Lehman W, Gulati J. Characterization of the Ca2+-switch in skeletal and cardiac muscles. Febs Letters. 251: 177-82. PMID 2753157 DOI: 10.1016/0014-5793(89)81450-4 |
0.412 |
|
| 1989 |
Lehman W. 35 kDa proteins are not components of vertebrate smooth muscle thin filaments. Biochimica Et Biophysica Acta. 996: 57-61. PMID 2736259 DOI: 10.1016/0167-4838(89)90094-0 |
0.499 |
|
| 1988 |
Marston SB, Redwood CS, Lehman W. Reversal of caldesmon function by anti-caldesmon antibodies confirms its role in the calcium regulation of vascular smooth muscle thin filaments. Biochemical and Biophysical Research Communications. 155: 197-202. PMID 2970847 DOI: 10.1016/S0006-291X(88)81068-4 |
0.445 |
|
| 1987 |
Lehman W, Sheldon A, Madonia W. Diversity in smooth muscle thin filament composition. Biochimica Et Biophysica Acta. 914: 35-9. PMID 3607060 DOI: 10.1016/0167-4838(87)90158-0 |
0.502 |
|
| 1986 |
Lehman W. Caldesmon association with smooth muscle thin filaments isolated in the presence and absence of calcium. Biochimica Et Biophysica Acta. 885: 88-90. PMID 3942796 DOI: 10.1016/0167-4889(86)90042-X |
0.445 |
|
| 1986 |
Lehman W. The effect of calcium on the aggregation of chicken gizzard thin filaments. Journal of Muscle Research and Cell Motility. 7: 537-49. PMID 3100573 DOI: 10.1007/Bf01753570 |
0.434 |
|
| 1985 |
Marston SB, Lehman W. Caldesmon is a Ca2+-regulatory component of native smooth-muscle thin filaments. The Biochemical Journal. 231: 517-22. PMID 2934055 DOI: 10.1042/Bj2310517 |
0.513 |
|
| 1984 |
Shima Y, Tsuchiya T, Lehman W, Matsumoto JJ. The characterization of invertebrate troponin C. Comparative Biochemistry and Physiology B. 79: 525-529. PMID 6518756 DOI: 10.1016/0305-0491(84)90360-2 |
0.331 |
|
| 1983 |
Lehman W. The distribution of troponin-like proteins on thin filaments of the bay scallop, aequipecten irradians. Journal of Muscle Research and Cell Motility. 4: 379-89. PMID 6348084 DOI: 10.1007/Bf00712003 |
0.42 |
|
| 1983 |
Lehman W. The ionic requirements for regulation by molluscan thin filaments. Biochimica Et Biophysica Acta. 745: 1-5. PMID 6221762 DOI: 10.1016/0167-4838(83)90162-0 |
0.486 |
|
| 1982 |
Lehman W. The location and periodicity of a troponin-T-like protein in the myofibril of the horseshoe crab Limulus polyphemus. Journal of Molecular Biology. 154: 385-91. PMID 6804635 DOI: 10.1016/0022-2836(82)90071-7 |
0.365 |
|
| 1982 |
Tsuchiya T, Head JF, Lehman W. The isolation and characterization of a troponin-C-like protein from the mantle muscle of the squid Loligo pealei Comparative Biochemistry and Physiology B. 71: 507-509. DOI: 10.1016/0305-0491(82)90416-3 |
0.393 |
|
| 1981 |
Lehman W. Thin-filament-linked regulation in molluscan muscles. Biochimica Et Biophysica Acta. 668: 349-56. PMID 6453619 DOI: 10.1016/0005-2795(81)90168-9 |
0.49 |
|
| 1978 |
Lehman W. Thick-filament-linked calcium regulation in vertebrate striated muscle. Nature. 274: 80-1. PMID 149254 DOI: 10.1038/274080A0 |
0.524 |
|
| 1978 |
Goldberg A, Lehman W. Troponin-like proteins from muscles of the scallop, Aequipecten irradians. The Biochemical Journal. 171: 413-8. PMID 148888 DOI: 10.1042/Bj1710413 |
0.485 |
|
| 1977 |
Lehman W. Calcium ion-dependent myosin from decapod-crustacean muscles. The Biochemical Journal. 163: 291-6. PMID 141278 DOI: 10.1042/Bj1630291 |
0.514 |
|
| 1976 |
Fine R, Lehman W, Head J, Blitz A. Troponin C in brain. Nature. 258: 260-7. PMID 1202358 DOI: 10.1038/258260A0 |
0.403 |
|
| 1976 |
Lehman W, Regenstein JM, Ransom AL. The stoichiometry of the components of arthropod thin filaments Bba - Protein Structure. 434: 215-222. PMID 938665 DOI: 10.1016/0005-2795(76)90053-2 |
0.404 |
|
| 1976 |
Lehman W. Phylogenetic diversity of the proteins regulating muscular contraction. International Review of Cytology. 44: 55-92. PMID 131113 DOI: 10.1016/S0074-7696(08)61647-2 |
0.465 |
|
| 1975 |
Lehman W, Szent-Györgyi AG. Regulation of muscular contraction. Distribution of actin control and myosin control in the animal kingdom. The Journal of General Physiology. 66: 1-30. PMID 125778 DOI: 10.1085/Jgp.66.1.1 |
0.696 |
|
| 1975 |
Lehman W. Hybrid troponin reconstituted from vertebrate and arthropod subunits. Nature. 255: 424-6. PMID 124018 DOI: 10.1038/255424A0 |
0.429 |
|
| 1974 |
Marston S, Lehman W. ADP binding to relaxed scallop myofibrils. Nature. 252: 38-9. PMID 4279338 DOI: 10.1038/252038A0 |
0.449 |
|
| 1974 |
Lehman W, Bullard B, Hammond K. Calcium dependent myosin from insect flight muscles Journal of General Physiology. 63: 553-563. PMID 4274833 DOI: 10.1085/Jgp.63.5.553 |
0.431 |
|
| 1973 |
Lehman W, Kendrick-Jones J, Szent-Gyorgyi AG. Myosin-linked Regulatory Systems: Comparative Studies Cold Spring Harbor Symposia On Quantitative Biology. 37: 319-330. DOI: 10.1101/Sqb.1973.037.01.042 |
0.703 |
|
| 1972 |
Lehman W, Szent-Györgyi G. Activation of the adenosine triphosphatase of Limulus polyphemus actomyosin by tropomyosin. The Journal of General Physiology. 59: 375-87. PMID 4260494 DOI: 10.1085/Jgp.59.4.375 |
0.521 |
|
| 1971 |
Lehman WJ, Rebhun LI. The structural elements responsible for contraction in the ciliate Spirostomum Protoplasma. 72: 153-178. PMID 5555985 DOI: 10.1007/Bf01279048 |
0.695 |
|
| 1970 |
Kendrick-Jones J, Lehman W, Szent-Györgyi AG. Regulation in molluscan muscles. Journal of Molecular Biology. 54: 313-26. PMID 4250215 DOI: 10.1016/0022-2836(70)90432-8 |
0.763 |
|
| Show low-probability matches. |
