Robert J. Handa - Publications

University of Arizona, Tucson, AZ 
 Colorado State University, Fort Collins, CO 
Neurondocrinology, steroid hormone receptors, stress and reproduction

233 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Sheng JA, Tan SML, Hale TM, Handa RJ. Androgens and Their Role in Regulating Sex Differences in the Hypothalamic/Pituitary/Adrenal Axis Stress Response and Stress-Related Behaviors. Androgens: Clinical Research and Therapeutics. 2: 261-274. PMID 35024695 DOI: 10.1089/andro.2021.0021  1
2021 Holsen LM, Huang G, Cherkerzian S, Aroner S, Loucks EB, Buka S, Handa RJ, Goldstein JM. Sex Differences in Hemoglobin A1c Levels Related to the Comorbidity of Obesity and Depression. Journal of Women's Health (2002). PMID 33534642 DOI: 10.1089/jwh.2020.8467  1
2021 Oyola MG, Johnson RC, Bauman BM, Frey KG, Russell AL, Cho-Clark M, Buban KN, Bishop-Lilly KA, Merrell DS, Handa RJ, Wu TJ. Gut microbiota and metabolic marker alteration following dietary isoflavone-photoperiod interaction. Endocrinology, Diabetes & Metabolism. 4: e00190. PMID 33532621 DOI: 10.1002/edm2.190  1
2021 Russell AL, Miller L, Yi H, Keil R, Handa RJ, Wu TJ.  Knockout of the circadian gene, Per2, disrupts corticosterone secretion and results in depressive-like behaviors and deficits in startle responses. Bmc Neuroscience. 22: 5. PMID 33509094 DOI: 10.1186/s12868-020-00607-y  1
2020 Sheng JA, Bales NJ, Myers SA, Bautista AI, Roueinfar M, Hale TM, Handa RJ. The Hypothalamic-Pituitary-Adrenal Axis: Development, Programming Actions of Hormones, and Maternal-Fetal Interactions. Frontiers in Behavioral Neuroscience. 14: 601939. PMID 33519393 DOI: 10.3389/fnbeh.2020.601939  1
2020 Huang G, Aroner SA, Bay CP, Gilman SE, Ghassabian A, Loucks EB, Buka SL, Handa RJ, Lasley BL, Bhasin S, Goldstein JM. Sex-dependent associations of maternal androgen levels with offspring BMI and weight trajectory from birth to early childhood. Journal of Endocrinological Investigation. PMID 32776198 DOI: 10.1007/S40618-020-01385-4  1
2020 Zuloaga DG, Heck AL, De Guzman RM, Handa RJ. Roles for androgens in mediating the sex differences of neuroendocrine and behavioral stress responses. Biology of Sex Differences. 11: 44. PMID 32727567 DOI: 10.1186/S13293-020-00319-2  1
2020 Heck AL, Sheng JA, Miller AM, Stover SA, Bales NJ, Tan SML, Daniels RM, Fleury TK, Handa RJ. Social isolation alters hypothalamic pituitary adrenal axis activity after chronic variable stress in male C57BL/6 mice. Stress (Amsterdam, Netherlands). 1-26. PMID 32093522 DOI: 10.1080/10253890.2020.1733962  1
2019 Heck AL, Thompson MK, Uht RM, Handa RJ. Sex-dependent mechanisms of glucocorticoid regulation of the mouse hypothalamic corticotropin-releasing hormone gene. Endocrinology. PMID 31754709 DOI: 10.1210/Endocr/Bqz012  1
2019 Borrow AP, Heck AL, Miller AM, Sheng JA, Stover SA, Daniels RM, Bales NJ, Fleury TK, Handa RJ. Chronic variable stress alters hypothalamic-pituitary-adrenal axis function in the female mouse. Physiology & Behavior. 112613. PMID 31299374 DOI: 10.1016/J.Physbeh.2019.112613  1
2019 Heck AL, Handa RJ. Androgens DRIVe sex biases in hypothalamic corticotropin releasing hormone gene expression after adrenalectomy of Mice. Endocrinology. PMID 31074799 DOI: 10.1210/En.2019-00238  1
2019 Bauman BM, Buban KN, Russell AL, Handa RJ, Wu TJ. Isoflavones Alter Hypothalamic-Pituitary-Adrenal Axis Response Following Photoperiod Alteration. Neuroscience. PMID 30880102 DOI: 10.1016/J.Neuroscience.2019.03.013  1
2019 McGivern RF, Mosso M, Freudenberg A, Handa RJ. Sex related biases for attending to object color versus object position are reflected in reaction time and accuracy. Plos One. 14: e0210272. PMID 30625223 DOI: 10.1371/Journal.Pone.0210272  1
2018 Russell AL, Handa RJ, Wu TJ. Sex-Dependent Effects of Mild Blast-induced Traumatic Brain Injury on Corticotropin-releasing Factor Receptor Gene Expression: Potential Link to Anxiety-like Behaviors. Neuroscience. 392: 1-12. PMID 30248435 DOI: 10.1016/J.Neuroscience.2018.09.014  1
2018 Huang G, Cherkerzian S, Loucks EB, Buka SL, Handa RJ, Lasley BL, Bhasin S, Goldstein JM. Sex Differences in the Prenatal Programming of Adult Metabolic Syndrome by Maternal Androgens. The Journal of Clinical Endocrinology and Metabolism. PMID 30113645 DOI: 10.1210/Jc.2018-01243  1
2018 Heck AL, Handa RJ. Sex differences in the hypothalamic-pituitary-adrenal axis' response to stress: an important role for gonadal hormones. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 30111811 DOI: 10.1038/S41386-018-0167-9  1
2018 Foradori CD, Healy JE, Zimmerman AD, Kemppainen RJ, Jones MA, Read CC, White BD, Yi KD, Hinds LR, Lacagnina AF, Quihuis AM, Breckenridge CB, Handa RJ. Characterization of activation of the hypothalamic-pituitary-adrenal axis by the herbicide atrazine in the female rat. Endocrinology. PMID 30060079 DOI: 10.1210/En.2018-00474  1
2018 Goldstein JM, Hale T, Foster SL, Tobet SA, Handa RJ. Sex differences in major depression and comorbidity of cardiometabolic disorders: impact of prenatal stress and immune exposures. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 30030541 DOI: 10.1038/S41386-018-0146-1  1
2018 Lehman M, Navarro V, Suchecki D, Handa R. Introduction to the PANS Special Issue. Journal of Neuroendocrinology. e12612. PMID 29851206 DOI: 10.1111/Jne.12612  1
2018 Russell AL, Richardson MR, Bauman BM, Hernandez IM, Saperstein S, Handa RJ, Wu TJ. Differential responses of the HPA axis to mild blast traumatic brain injury in male and female mice. Endocrinology. PMID 29701827 DOI: 10.1210/En.2018-00203  1
2018 Frahm KA, Handa RJ, Tobet SA. Embryonic Exposure to Dexamethasone Affects Nonneuronal Cells in the Adult Paraventricular Nucleus of the Hypothalamus. Journal of the Endocrine Society. 2: 140-153. PMID 29383333 DOI: 10.1210/Js.2017-00439  1
2017 Breckenridge CB, Foradori CD, Sawhney Coder P, Simpkins JW, Sielken RL, Handa RJ. Changes in Sensitivity to the Effects of Atrazine on the Luteinizing Hormone Surge in Female Sprague-Dawley Rats after Repeated Daily Doses: Correlation with Liver Enzyme Expression. Birth Defects Research. PMID 29134775 DOI: 10.1002/Bdr2.1130  1
2017 Oyola MG, Handa RJ. Hypothalamic-pituitary-adrenal and hypothalamic-pituitary-gonadal axes: sex differences in regulation of stress responsivity. Stress (Amsterdam, Netherlands). 1-19. PMID 28859530 DOI: 10.1080/10253890.2017.1369523  1
2017 Oyola MG, Thompson MK, Handa AZ, Handa RJ. Distribution and Chemical Composition of Estrogen Receptor β Neurons in the Paraventricular Nucleus of the Female and Male Mouse Hypothalamus. The Journal of Comparative Neurology. PMID 28758220 DOI: 10.1002/Cne.24295  1
2017 Foradori CD, Zimmerman AD, Coder PS, Peachee VL, Handa RJ, Kimber I, Pruett SB, Breckenridge CB. Lack of immunotoxic effects of repeated exposure to atrazine associated with the adaptation of adrenal gland activation. Regulatory Toxicology and Pharmacology : Rtp. PMID 28736286 DOI: 10.1016/J.Yrtph.2017.07.017  1
2017 Russell AL, Grimes JM, Cruthirds DF, Westerfield J, Wooten L, Keil M, Weiser MJ, Landauer MR, Handa RJ, Wu TJ, Larco DO. Dietary Isoflavone-Dependent and Estradiol Replacement Effects on Body Weight in the Ovariectomized (OVX) Rat. Hormone and Metabolic Research = Hormon- Und Stoffwechselforschung = Hormones Et Metabolisme. PMID 28482370 DOI: 10.1055/S-0043-108250  1
2017 Russell AL, Grimes JM, Larco DO, Cruthirds DF, Westerfield J, Wooten L, Keil M, Weiser MJ, Landauer MR, Handa RJ, Wu TJ. The interaction of dietary isoflavones and estradiol replacement on behavior and brain-derived neurotrophic factor in the ovariectomized rat. Neuroscience Letters. PMID 28077306 DOI: 10.1016/J.Neulet.2017.01.011  1
2016 Goldstein JM, Holsen L, Huang G, Hammond BD, James-Todd T, Cherkerzian S, Hale TM, Handa RJ. Prenatal stress-immune programming of sex differences in comorbidity of depression and obesity/metabolic syndrome. Dialogues in Clinical Neuroscience. 18: 425-436. PMID 28179814  1
2016 Hiroi R, Carbone DL, Zuloaga DG, Bimonte-Nelson HA, Handa RJ. Sex-dependent programming effects of prenatal glucocorticoid treatment on the developing serotonin system and stress-related behaviors in adulthood Neuroscience. 320: 43-56. DOI: 10.1016/j.neuroscience.2016.01.055  1
2015 Acevedo-Rodriguez A, Mani SK, Handa RJ. Oxytocin and Estrogen Receptor β in the Brain: An Overview. Frontiers in Endocrinology. 6: 160. PMID 26528239 DOI: 10.3389/Fendo.2015.00160  1
2015 Breckenridge CB, Sawhney Coder P, Tisdel MO, Simpkins JW, Yi KD, Foradori CD, Handa RJ. Effect of Age, Duration of Exposure, and Dose of Atrazine on Sexual Maturation and the Luteinizing Hormone Surge in the Female Sprague-Dawley Rat. Birth Defects Research. Part B, Developmental and Reproductive Toxicology. PMID 26439775 DOI: 10.1002/Bdrb.21154  1
2015 Oyola MG, Zuloaga DG, Carbone D, Malysz AM, Acevedo-Rodriguez A, Handa RJ, Mani SK. CYP7B1 Enzyme Deletion Impairs Reproductive Behaviors in Male Mice. Endocrinology. 156: 2150-61. PMID 25849728 DOI: 10.1210/En.2014-1786  1
2015 Handa RJ, McGivern RF. Steroid hormones, receptors, and perceptual and cognitive sex differences in the visual system. Current Eye Research. 40: 110-27. PMID 25153712 DOI: 10.3109/02713683.2014.952826  1
2014 Sollars PJ, Weiser MJ, Kudwa AE, Bramley JR, Ogilvie MD, Spencer RL, Handa RJ, Pickard GE. Altered entrainment to the day/night cycle attenuates the daily rise in circulating corticosterone in the mouse. Plos One. 9: e111944. PMID 25365210 DOI: 10.1371/Journal.Pone.0111944  1
2014 Stratton MS, Staros M, Budefeld T, Searcy BT, Nash C, Eitel C, Carbone D, Handa RJ, Majdic G, Tobet SA. Embryonic GABA(B) receptor blockade alters cell migration, adult hypothalamic structure, and anxiety- and depression-like behaviors sex specifically in mice. Plos One. 9: e106015. PMID 25162235 DOI: 10.1371/Journal.Pone.0106015  1
2014 Mani SK, Anselmo-Franci J, Lara H, Suchecki D, Poletini MO, Handa RJ, Wu TY. Neuroendocrine regulation and homeostasis. Journal of Neuroendocrinology. 26: 555-6. PMID 25059493 DOI: 10.1111/jne.12184  1
2014 Foradori CD, Sawhney Coder P, Tisdel M, Yi KD, Simpkins JW, Handa RJ, Breckenridge CB. The effect of atrazine administered by gavage or in diet on the LH surge and reproductive performance in intact female Sprague-Dawley and Long Evans rats. Birth Defects Research. Part B, Developmental and Reproductive Toxicology. 101: 262-75. PMID 24831581 DOI: 10.1002/Bdrb.21109  1
2014 Kudwa AE, McGivern RF, Handa RJ. Estrogen receptor β and oxytocin interact to modulate anxiety-like behavior and neuroendocrine stress reactivity in adult male and female rats. Physiology & Behavior. 129: 287-96. PMID 24631553 DOI: 10.1016/j.physbeh.2014.03.004  1
2014 Goldstein JM, Handa RJ, Tobet SA. Disruption of fetal hormonal programming (prenatal stress) implicates shared risk for sex differences in depression and cardiovascular disease. Frontiers in Neuroendocrinology. 35: 140-58. PMID 24355523 DOI: 10.1016/J.Yfrne.2013.12.001  1
2014 Handa RJ, Weiser MJ. Gonadal steroid hormones and the hypothalamo-pituitary-adrenal axis. Frontiers in Neuroendocrinology. 35: 197-220. PMID 24246855 DOI: 10.1016/J.Yfrne.2013.11.001  1
2014 Zuloaga DG, Zuloaga KL, Hinds LR, Carbone DL, Handa RJ. Estrogen receptor β expression in the mouse forebrain: age and sex differences. The Journal of Comparative Neurology. 522: 358-71. PMID 23818057 DOI: 10.1002/Cne.23400  1
2014 Goldstein JM, Holsen L, Handa R, Tobet S. Fetal hormonal programming of sex differences in depression: Linking women's mental health with sex differences in the brain across the lifespan Frontiers in Neuroscience. DOI: 10.3389/fnins.2014.00247  1
2014 Handa RJ, Larco DO, Wu TJ. Steroid Hormone Action in Health and Disease Reference Module in Biomedical Research. DOI: 10.1016/B978-0-12-801238-3.00099-4  1
2013 Hiroi R, Handa RJ. Estrogen receptor-β regulates human tryptophan hydroxylase-2 through an estrogen response element in the 5' untranslated region. Journal of Neurochemistry. 127: 487-95. PMID 24033289 DOI: 10.1111/jnc.12401  1
2013 Handa RJ, Kudwa AE, Donner NC, McGivern RF, Brown R. Central 5-alpha reduction of testosterone is required for testosterone's inhibition of the hypothalamo-pituitary-adrenal axis response to restraint stress in adult male rats. Brain Research. 1529: 74-82. PMID 23880372 DOI: 10.1016/j.brainres.2013.07.021  1
2013 Hiroi R, Lacagnina AF, Hinds LR, Carbone DG, Uht RM, Handa RJ. The androgen metabolite, 5α-androstane-3β,17β-diol (3β-diol), activates the oxytocin promoter through an estrogen receptor-β pathway. Endocrinology. 154: 1802-12. PMID 23515287 DOI: 10.1210/En.2012-2253  1
2013 Tobet SA, Handa RJ, Goldstein JM. Sex-dependent pathophysiology as predictors of comorbidity of major depressive disorder and cardiovascular disease. Pflã¼Gers Archiv : European Journal of Physiology. 465: 585-94. PMID 23503726 DOI: 10.1007/S00424-013-1248-6  1
2013 Dorchies OM, Reutenauer-Patte J, Dahmane E, Ismail HM, Petermann O, Patthey- Vuadens O, Comyn SA, Gayi E, Piacenza T, Handa RJ, Décosterd LA, Ruegg UT. The anticancer drug tamoxifen counteracts the pathology in a mouse model of duchenne muscular dystrophy. The American Journal of Pathology. 182: 485-504. PMID 23332367 DOI: 10.1016/j.ajpath.2012.10.018  1
2013 Makris N, Swaab DF, van der Kouwe A, Abbs B, Boriel D, Handa RJ, Tobet S, Goldstein JM. Volumetric parcellation methodology of the human hypothalamus in neuroimaging: normative data and sex differences. Neuroimage. 69: 1-10. PMID 23247186 DOI: 10.1016/J.Neuroimage.2012.12.008  1
2013 Carbone DL, Handa RJ. Sex and stress hormone influences on the expression and activity of brain-derived neurotrophic factor. Neuroscience. 239: 295-303. PMID 23211562 DOI: 10.1016/j.neuroscience.2012.10.073  1
2013 Foradori CD, Zimmerman AD, Hinds LR, Zuloaga KL, Breckenridge CB, Handa RJ. Atrazine inhibits pulsatile gonadotropin-releasing hormone (GnRH) release without altering GnRH messenger RNA or protein levels in the female rat. Biology of Reproduction. 88: 9. PMID 23197165 DOI: 10.1095/Biolreprod.112.102277  1
2012 Zuloaga KL, Swift SN, Gonzales RJ, Wu TJ, Handa RJ. The androgen metabolite, 5α-androstane-3β,17β-diol, decreases cytokine-induced cyclooxygenase-2, vascular cell adhesion molecule-1 expression, and P-glycoprotein expression in male human brain microvascular endothelial cells. Endocrinology. 153: 5949-60. PMID 23117931 DOI: 10.1210/En.2012-1316  1
2012 Carbone DL, Zuloaga DG, Lacagnina AF, Handa RJ. Prepro-thyrotropin releasing hormone expressing neurons in the juxtaparaventricular region of the lateral hypothalamus are activated by leptin and altered by prenatal glucocorticoid exposure. Brain Research. 1477: 19-26. PMID 22981312 DOI: 10.1016/J.Brainres.2012.08.020  1
2012 Carbone DL, Zuloaga DG, Lacagnina AF, McGivern RF, Handa RJ. Exposure to dexamethasone during late gestation causes female-specific decreases in core body temperature and prepro-thyrotropin-releasing hormone expression in the paraventricular nucleus of the hypothalamus in rats. Physiology & Behavior. 108: 6-12. PMID 22884559 DOI: 10.1016/J.Physbeh.2012.07.010  1
2012 Zuloaga DG, Yahn SL, Pang Y, Quihuis AM, Oyola MG, Reyna A, Thomas P, Handa RJ, Mani SK. Distribution and estrogen regulation of membrane progesterone receptor-β in the female rat brain. Endocrinology. 153: 4432-43. PMID 22778216 DOI: 10.1210/En.2012-1469  1
2012 Mani SK, Lara H, Romero C, Handa RJ, Wu TJ. Advances in neuroendocrine mechanisms. Hormone and Metabolic Research = Hormon- Und Stoffwechselforschung = Hormones Et Mã©Tabolisme. 44: 561-2. PMID 22773370 DOI: 10.1055/s-0032-1316344  1
2012 Larco DO, Cruthirds DF, Weiser MJ, Handa RJ, Wu TJ. The effect of chronic immobilization stress on leptin signaling in the ovariectomized (OVX) rat. Endocrine. 42: 717-25. PMID 22706604 DOI: 10.1007/S12020-012-9716-X  1
2012 Zuloaga DG, Carbone DL, Handa RJ. Prenatal dexamethasone selectively decreases calretinin expression in the adult female lateral amygdala. Neuroscience Letters. 521: 109-14. PMID 22668856 DOI: 10.1016/j.neulet.2012.05.058  1
2012 Fernández-Guasti A, Fiedler JL, Herrera L, Handa RJ. Sex, stress, and mood disorders: at the intersection of adrenal and gonadal hormones. Hormone and Metabolic Research = Hormon- Und Stoffwechselforschung = Hormones Et Mã©Tabolisme. 44: 607-18. PMID 22581646 DOI: 10.1055/s-0032-1312592  1
2012 Zuloaga KL, O'Connor DT, Handa RJ, Gonzales RJ. Estrogen receptor beta dependent attenuation of cytokine-induced cyclooxygenase-2 by androgens in human brain vascular smooth muscle cells and rat mesenteric arteries. Steroids. 77: 835-44. PMID 22542504 DOI: 10.1016/J.Steroids.2012.04.013  1
2012 Handa RJ, Mani SK, Uht RM. Estrogen receptors and the regulation of neural stress responses. Neuroendocrinology. 96: 111-8. PMID 22538291 DOI: 10.1159/000338397  1
2012 Sharma D, Handa RJ, Uht RM. The ERβ ligand 5α-androstane, 3β,17β-diol (3β-diol) regulates hypothalamic oxytocin (Oxt) gene expression. Endocrinology. 153: 2353-61. PMID 22434086 DOI: 10.1210/En.2011-1002  1
2012 McGivern RF, Adams B, Handa RJ, Pineda JA. Men and women exhibit a differential bias for processing movement versus objects. Plos One. 7: e32238. PMID 22431972 DOI: 10.1371/journal.pone.0032238  1
2012 Zuloaga DG, Carbone DL, Quihuis A, Hiroi R, Chong DL, Handa RJ. Perinatal dexamethasone-induced alterations in apoptosis within the hippocampus and paraventricular nucleus of the hypothalamus are influenced by age and sex. Journal of Neuroscience Research. 90: 1403-12. PMID 22388926 DOI: 10.1002/jnr.23026  1
2012 Oyola MG, Portillo W, Reyna A, Foradori CD, Kudwa A, Hinds L, Handa RJ, Mani SK. Anxiolytic effects and neuroanatomical targets of estrogen receptor-β (ERβ) activation by a selective ERβ agonist in female mice. Endocrinology. 153: 837-46. PMID 22186418 DOI: 10.1210/En.2011-1674  1
2012 Carbone DL, Zuloaga DG, Hiroi R, Foradori CD, Legare ME, Handa RJ. Prenatal dexamethasone exposure potentiates diet-induced hepatosteatosis and decreases plasma IGF-I in a sex-specific fashion. Endocrinology. 153: 295-306. PMID 22067322 DOI: 10.1210/En.2011-1601  1
2012 Handa RJ, Ogawa S, Wang JM, Herbison AE. Roles for oestrogen receptor β in adult brain function. Journal of Neuroendocrinology. 24: 160-73. PMID 21851428 DOI: 10.1111/j.1365-2826.2011.02206.x  1
2011 Handa RJ, Sharma D, Uht R. A role for the androgen metabolite, 5alpha androstane 3beta, 17beta diol (3β-diol) in the regulation of the hypothalamo-pituitary-adrenal axis. Frontiers in Endocrinology. 2: 65. PMID 22649380 DOI: 10.3389/Fendo.2011.00065  1
2011 Zuloaga DG, Carbone DL, Hiroi R, Chong DL, Handa RJ. Dexamethasone induces apoptosis in the developing rat amygdala in an age-, region-, and sex-specific manner. Neuroscience. 199: 535-47. PMID 22008524 DOI: 10.1016/j.neuroscience.2011.09.052  1
2011 Simpkins JW, Swenberg JA, Weiss N, Brusick D, Eldridge JC, Stevens JT, Handa RJ, Hovey RC, Plant TM, Pastoor TP, Breckenridge CB. Atrazine and breast cancer: a framework assessment of the toxicological and epidemiological evidence. Toxicological Sciences : An Official Journal of the Society of Toxicology. 123: 441-59. PMID 21768606 DOI: 10.1093/Toxsci/Kfr176  1
2011 Foradori CD, Hinds LR, Quihuis AM, Lacagnina AF, Breckenridge CB, Handa RJ. The differential effect of atrazine on luteinizing hormone release in adrenalectomized adult female Wistar rats. Biology of Reproduction. 85: 684-9. PMID 21677308 DOI: 10.1095/Biolreprod.111.092452  1
2011 Healy JE, Gearhart CN, Bateman JL, Handa RJ, Florant GL. AMPK and ACCchange with fasting and physiological condition in euthermic and hibernating golden-mantled ground squirrels (Callospermophilus lateralis). Comparative Biochemistry and Physiology. Part a, Molecular & Integrative Physiology. 159: 322-31. PMID 21473923 DOI: 10.1016/j.cbpa.2011.03.026  1
2011 Miller L, Foradori CD, Lalmansingh AS, Sharma D, Handa RJ, Uht RM. Histone deacetylase 1 (HDAC1) participates in the down-regulation of corticotropin releasing hormone gene (crh) expression. Physiology & Behavior. 104: 312-20. PMID 21463644 DOI: 10.1016/J.Physbeh.2011.03.026  1
2010 Dooley GP, Ashley AK, Legare ME, Handa RJ, Hanneman WH. Proteomic analysis of diaminochlorotriazine (DACT) adducts in three brain regions of Wistar rats. Toxicology Letters. 199: 17-21. PMID 20688138 DOI: 10.1016/J.Toxlet.2010.07.014  1
2010 Florant GL, Fenn AM, Healy JE, Wilkerson GK, Handa RJ. To eat or not to eat: the effect of AICAR on food intake regulation in yellow-bellied marmots (Marmota flaviventris). The Journal of Experimental Biology. 213: 2031-7. PMID 20511516 DOI: 10.1242/jeb.039131  1
2010 Kudwa AE, López FJ, McGivern RF, Handa RJ. A selective androgen receptor modulator enhances male-directed sexual preference, proceptive behavior, and lordosis behavior in sexually experienced, but not sexually naive, female rats. Endocrinology. 151: 2659-68. PMID 20392832 DOI: 10.1210/en.2009-1289  1
2010 Weiser MJ, Foradori CD, Handa RJ. Estrogen receptor beta activation prevents glucocorticoid receptor-dependent effects of the central nucleus of the amygdala on behavior and neuroendocrine function. Brain Research. 1336: 78-88. PMID 20381466 DOI: 10.1016/J.Brainres.2010.03.098  1
2010 Osterlund KL, Handa RJ, Gonzales RJ. Dihydrotestosterone alters cyclooxygenase-2 levels in human coronary artery smooth muscle cells. American Journal of Physiology. Endocrinology and Metabolism. 298: E838-45. PMID 20103743 DOI: 10.1152/Ajpendo.00693.2009  1
2010 Handa RJ, Chung WCJ. Gender and Stress Encyclopedia of Stress. 115-121. DOI: 10.1016/B978-012373947-6.00170-7  1
2010 Handa RJ, Pak TR. Androgen Action Encyclopedia of Stress. 171-175. DOI: 10.1016/B978-012373947-6.00032-5  1
2010 Tobet SA, Handa RJ. Gonadal Steroid Actions on Brain Encyclopedia of Neuroscience. 951-957. DOI: 10.1016/B978-008045046-9.01171-2  1
2010 Handa RJ, McGivern RF. Stress Response: Sex Differences Encyclopedia of Neuroscience. 511-517. DOI: 10.1016/B978-008045046-9.00100-5  1
2009 McGivern RF, Zuloaga DG, Handa RJ. Sex differences in stress-induced hyperthermia in rats: restraint versus confinement. Physiology & Behavior. 98: 416-20. PMID 19616565 DOI: 10.1016/j.physbeh.2009.07.004  1
2009 Foradori CD, Hinds LR, Hanneman WH, Handa RJ. Effects of atrazine and its withdrawal on gonadotropin-releasing hormone neuroendocrine function in the adult female Wistar rat. Biology of Reproduction. 81: 1099-105. PMID 19605789 DOI: 10.1095/Biolreprod.109.077453  1
2009 Donner N, Handa RJ. Estrogen receptor beta regulates the expression of tryptophan-hydroxylase 2 mRNA within serotonergic neurons of the rat dorsal raphe nuclei. Neuroscience. 163: 705-18. PMID 19559077 DOI: 10.1016/j.neuroscience.2009.06.046  1
2009 Pak TR, Chung WC, Hinds LR, Handa RJ. Arginine vasopressin regulation in pre- and postpubertal male rats by the androgen metabolite 3beta-diol. American Journal of Physiology. Endocrinology and Metabolism. 296: E1409-13. PMID 19383875 DOI: 10.1152/Ajpendo.00037.2009  1
2009 Foradori CD, Hinds LR, Hanneman WH, Legare ME, Clay CM, Handa RJ. Atrazine inhibits pulsatile luteinizing hormone release without altering pituitary sensitivity to a gonadotropin-releasing hormone receptor agonist in female Wistar rats. Biology of Reproduction. 81: 40-5. PMID 19299313 DOI: 10.1095/Biolreprod.108.075713  1
2009 Zuloaga DG, McGivern RF, Handa RJ. Organizational influence of the postnatal testosterone surge on the circadian rhythm of core body temperature of adult male rats. Brain Research. 1268: 68-75. PMID 19272357 DOI: 10.1016/j.brainres.2009.02.048  1
2009 Magee C, Foradori CD, Bruemmer JE, Arreguin-Arevalo JA, McCue PM, Handa RJ, Squires EL, Clay CM. Biological and anatomical evidence for kisspeptin regulation of the hypothalamic-pituitary-gonadal axis of estrous horse mares. Endocrinology. 150: 2813-21. PMID 19228887 DOI: 10.1210/En.2008-1698  1
2009 Handa RJ, Weiser MJ, Zuloaga DG. A role for the androgen metabolite, 5alpha-androstane-3beta,17beta-diol, in modulating oestrogen receptor beta-mediated regulation of hormonal stress reactivity. Journal of Neuroendocrinology. 21: 351-8. PMID 19207807 DOI: 10.1111/J.1365-2826.2009.01840.X  1
2009 Weiser MJ, Handa RJ. Estrogen impairs glucocorticoid dependent negative feedback on the hypothalamic-pituitary-adrenal axis via estrogen receptor alpha within the hypothalamus. Neuroscience. 159: 883-95. PMID 19166915 DOI: 10.1016/J.Neuroscience.2008.12.058  1
2009 Weiser MJ, Wu TJ, Handa RJ. Estrogen receptor-beta agonist diarylpropionitrile: biological activities of R- and S-enantiomers on behavior and hormonal response to stress. Endocrinology. 150: 1817-25. PMID 19074580 DOI: 10.1210/En.2008-1355  1
2009 Pak TR, Chung WC, Hinds LR, Handa RJ. Arginine vasopressin regulation in pre- and postpubertal male rats by the androgen metabolite 3β-diol (American Journal of Physiology - Endocrinology and Metabolism (2009) 296, 59, (E1409-E1413) DOI: 10.1152/ajpendo.00037.2009) American Journal of Physiology - Endocrinology and Metabolism. 297: E270. DOI: 10.1152/ajpendo.zh1-5737-corr.2009  1
2008 Weiser MJ, Goel N, Sandau US, Bale TL, Handa RJ. Androgen regulation of corticotropin-releasing hormone receptor 2 (CRHR2) mRNA expression and receptor binding in the rat brain. Experimental Neurology. 214: 62-8. PMID 18706413 DOI: 10.1016/J.Expneurol.2008.07.013  1
2008 Foradori CD, Handa RJ. Living or dying in three quarter time: neonatal orchestration of hippocampal cell death pathways by androgens and excitatory GABA. Experimental Neurology. 213: 1-6. PMID 18617165 DOI: 10.1016/J.Expneurol.2008.04.035  1
2008 Wegorzewska IN, Walters K, Weiser MJ, Cruthirds DF, Ewell E, Larco DO, Handa RJ, Wu TJ. Postovariectomy weight gain in female rats is reversed by estrogen receptor alpha agonist, propylpyrazoletriol. American Journal of Obstetrics and Gynecology. 199: 67.e1-5. PMID 18241818 DOI: 10.1016/J.Ajog.2007.11.054  1
2008 Foradori CD, Weiser MJ, Handa RJ. Non-genomic actions of androgens. Frontiers in Neuroendocrinology. 29: 169-81. PMID 18093638 DOI: 10.1016/J.Yfrne.2007.10.005  1
2008 Handa RJ, Pak TR, Kudwa AE, Lund TD, Hinds L. An alternate pathway for androgen regulation of brain function: activation of estrogen receptor beta by the metabolite of dihydrotestosterone, 5alpha-androstane-3beta,17beta-diol. Hormones and Behavior. 53: 741-52. PMID 18067894 DOI: 10.1016/J.Yhbeh.2007.09.012  1
2008 Perez DS, Handa RJ, Yang RS, Campain JA. Gene expression changes associated with altered growth and differentiation in benzo[a]pyrene or arsenic exposed normal human epidermal keratinocytes. Journal of Applied Toxicology : Jat. 28: 491-508. PMID 17879257 DOI: 10.1002/Jat.1301  1
2008 Weiser MJ, Foradori CD, Handa RJ. Estrogen receptor beta in the brain: from form to function. Brain Research Reviews. 57: 309-20. PMID 17662459 DOI: 10.1016/J.Brainresrev.2007.05.013  1
2007 Handa RJ, Zuloaga DG, McGivern RF. Prenatal ethanol exposure alters core body temperature and corticosterone rhythms in adult male rats. Alcohol (Fayetteville, N.Y.). 41: 567-75. PMID 18047910 DOI: 10.1016/J.Alcohol.2007.09.004  1
2007 Chung WC, Pak TR, Suzuki S, Pouliot WA, Andersen ME, Handa RJ. Detection and localization of an estrogen receptor beta splice variant protein (ERbeta2) in the adult female rat forebrain and midbrain regions. The Journal of Comparative Neurology. 505: 249-67. PMID 17879269 DOI: 10.1002/Cne.21490  1
2007 Foradori CD, Werner SB, Sandau US, Clapp TR, Handa RJ. Activation of the androgen receptor alters the intracellular calcium response to glutamate in primary hippocampal neurons and modulates sarco/endoplasmic reticulum calcium ATPase 2 transcription. Neuroscience. 149: 155-64. PMID 17870249 DOI: 10.1016/J.Neuroscience.2007.06.054  1
2007 Handa RJ, Zoeller RT, McGivern RF. Changes in vasoactive intestinal peptide and arginine vasopressin expression in the suprachiasmatic nucleus of the rat brain following footshock stress. Neuroscience Letters. 425: 99-104. PMID 17826907 DOI: 10.1016/J.Neulet.2007.08.044  1
2007 Foradori CD, Lund TD, Nagahara AH, Koenig JI, Handa RJ. Corticotropin-releasing hormone heterogeneous nuclear RNA (hnRNA) and immunoreactivity are induced in extrahypothalamic brain sites by kainic-acid-induced seizures and are modulated by estrogen. Brain Research. 1164: 44-54. PMID 17631870 DOI: 10.1016/J.Brainres.2007.05.064  1
2007 Foradori CD, Amstalden M, Coolen LM, Singh SR, McManus CJ, Handa RJ, Goodman RL, Lehman MN. Orphanin FQ: evidence for a role in the control of the reproductive neuroendocrine system. Endocrinology. 148: 4993-5001. PMID 17615146 DOI: 10.1210/En.2007-0011  1
2007 Kudwa AE, Boon WC, Simpson ER, Handa RJ, Rissman EF. Dietary phytoestrogens dampen female sexual behavior in mice with a disrupted aromatase enzyme gene. Behavioral Neuroscience. 121: 356-61. PMID 17469925 DOI: 10.1037/0735-7044.121.2.356  1
2007 Pak TR, Chung WC, Hinds LR, Handa RJ. Estrogen receptor-beta mediates dihydrotestosterone-induced stimulation of the arginine vasopressin promoter in neuronal cells. Endocrinology. 148: 3371-82. PMID 17412808 DOI: 10.1210/En.2007-0086  1
2007 Sandau US, Handa RJ. Glucocorticoids exacerbate hypoxia-induced expression of the pro-apoptotic gene Bnip3 in the developing cortex. Neuroscience. 144: 482-94. PMID 17110051 DOI: 10.1016/J.Neuroscience.2006.10.003  1
2007 Pak TR, Handa RJ. Steroid Hormone Receptors and Sex Differences in Behavior Sex Differences in the Brain: From Genes to Behavior. DOI: 10.1093/acprof:oso/9780195311587.003.0007  1
2006 Sandau US, Handa RJ. Localization and developmental ontogeny of the pro-apoptotic Bnip3 mRNA in the postnatal rat cortex and hippocampus. Brain Research. 1100: 55-63. PMID 16765336 DOI: 10.1016/J.Brainres.2006.05.006  1
2006 Chung WC, Pak TR, Weiser MJ, Hinds LR, Andersen ME, Handa RJ. Progestin receptor expression in the developing rat brain depends upon activation of estrogen receptor alpha and not estrogen receptor beta. Brain Research. 1082: 50-60. PMID 16513095 DOI: 10.1016/J.Brainres.2006.01.109  1
2006 Lund TD, Hinds LR, Handa RJ. The androgen 5alpha-dihydrotestosterone and its metabolite 5alpha-androstan-3beta, 17beta-diol inhibit the hypothalamo-pituitary-adrenal response to stress by acting through estrogen receptor beta-expressing neurons in the hypothalamus. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 1448-56. PMID 16452668 DOI: 10.1523/Jneurosci.3777-05.2006  1
2006 Pak TR, Chung WC, Roberts JL, Handa RJ. Ligand-independent effects of estrogen receptor beta on mouse gonadotropin-releasing hormone promoter activity. Endocrinology. 147: 1924-31. PMID 16439454 DOI: 10.1210/En.2005-1297  1
2005 Kuehl-Kovarik MC, Partin KM, Handa RJ, Dudek FE. Spike-dependent depolarizing afterpotentials contribute to endogenous bursting in gonadotropin releasing hormone neurons. Neuroscience. 134: 295-300. PMID 15961246 DOI: 10.1016/J.Neuroscience.2005.03.047  1
2005 Setchell KD, Clerici C, Lephart ED, Cole SJ, Heenan C, Castellani D, Wolfe BE, Nechemias-Zimmer L, Brown NM, Lund TD, Handa RJ, Heubi JE. S-equol, a potent ligand for estrogen receptor beta, is the exclusive enantiomeric form of the soy isoflavone metabolite produced by human intestinal bacterial flora. The American Journal of Clinical Nutrition. 81: 1072-9. PMID 15883431 DOI: 10.1093/Ajcn/81.5.1072  1
2005 Suzuki S, Handa RJ. Estrogen receptor-beta, but not estrogen receptor-alpha, is expressed in prolactin neurons of the female rat paraventricular and supraoptic nuclei: comparison with other neuropeptides. The Journal of Comparative Neurology. 484: 28-42. PMID 15717309 DOI: 10.1002/Cne.20457  1
2005 Lund TD, Rovis T, Chung WC, Handa RJ. Novel actions of estrogen receptor-beta on anxiety-related behaviors. Endocrinology. 146: 797-807. PMID 15514081 DOI: 10.1210/En.2004-1158  1
2005 Pak TR, Chung WC, Lund TD, Hinds LR, Clay CM, Handa RJ. The androgen metabolite, 5alpha-androstane-3beta, 17beta-diol, is a potent modulator of estrogen receptor-beta1-mediated gene transcription in neuronal cells. Endocrinology. 146: 147-55. PMID 15471969 DOI: 10.1210/En.2004-0871  1
2004 Miller WJ, Suzuki S, Miller LK, Handa R, Uht RM. Estrogen receptor (ER)beta isoforms rather than ERalpha regulate corticotropin-releasing hormone promoter activity through an alternate pathway. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 10628-35. PMID 15564578 DOI: 10.1523/Jneurosci.5540-03.2004  1
2004 Lephart ED, Setchell KD, Handa RJ, Lund TD. Behavioral effects of endocrine-disrupting substances: phytoestrogens. Ilar Journal / National Research Council, Institute of Laboratory Animal Resources. 45: 443-54. PMID 15454683 DOI: 10.1093/Ilar.45.4.443  1
2004 Lund TD, Munson DJ, Haldy ME, Handa RJ. Dihydrotestosterone may inhibit hypothalamo-pituitary-adrenal activity by acting through estrogen receptor in the male mouse. Neuroscience Letters. 365: 43-7. PMID 15234470 DOI: 10.1016/J.Neulet.2004.04.035  1
2004 Suzuki S, Handa RJ. Regulation of estrogen receptor-beta expression in the female rat hypothalamus: differential effects of dexamethasone and estradiol. Endocrinology. 145: 3658-70. PMID 15087431 DOI: 10.1210/En.2003-1688  1
2004 McMullin TS, Andersen ME, Nagahara A, Lund TD, Pak T, Handa RJ, Hanneman WH. Evidence that atrazine and diaminochlorotriazine inhibit the estrogen/progesterone induced surge of luteinizing hormone in female Sprague-Dawley rats without changing estrogen receptor action. Toxicological Sciences : An Official Journal of the Society of Toxicology. 79: 278-86. PMID 15056801 DOI: 10.1093/Toxsci/Kfh127  1
2004 Lund TD, Munson DJ, Haldy ME, Handa RJ. Androgen inhibits, while oestrogen enhances, restraint-induced activation of neuropeptide neurones in the paraventricular nucleus of the hypothalamus. Journal of Neuroendocrinology. 16: 272-8. PMID 15049858 DOI: 10.1111/J.0953-8194.2004.01167.X  1
2004 Beck SG, Handa RJ. Dehydroepiandrosterone (DHEA): a misunderstood adrenal hormone and spine-tingling neurosteroid? Endocrinology. 145: 1039-41. PMID 14976151 DOI: 10.1210/En.2003-1703  1
2004 Lund TD, Munson DJ, Adlercreutz H, Handa RJ, Lephart ED. Androgen receptor expression in the rat prostate is down-regulated by dietary phytoestrogens. Reproductive Biology and Endocrinology : Rb&E. 2: 5. PMID 14728729 DOI: 10.1186/1477-7827-2-5  1
2004 Lund TD, Munson DJ, Haldy ME, Setchell KD, Lephart ED, Handa RJ. Equol is a novel anti-androgen that inhibits prostate growth and hormone feedback. Biology of Reproduction. 70: 1188-95. PMID 14681200 DOI: 10.1095/Biolreprod.103.023713  1
2003 Bae DS, Handa RJ, Yang RS, Campain JA. Gene expression patterns as potential molecular biomarkers for malignant transformation in human keratinocytes treated with MNNG, arsenic, or a metal mixture. Toxicological Sciences : An Official Journal of the Society of Toxicology. 74: 32-42. PMID 12773770 DOI: 10.1093/toxsci/kfg124  1
2002 Alexander TH, Handa RJ, McGivern RF. Inhibition of prolactin secretion from the male rat anterior pituitary by cryptic sequences of prothyrotropin releasing hormone, ProTRH178-199 and ProTRH186-199. Endocrine. 19: 313-8. PMID 12624432 DOI: 10.1385/Endo:19:3:313  1
2002 Jordan CL, Christensen SE, Handa RJ, Anderson JL, Pouliot WA, Breedlove SM. Evidence that androgen acts through NMDA receptors to affect motoneurons in the rat spinal nucleus of the bulbocavernosus. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 9567-72. PMID 12417681 DOI: 10.1523/Jneurosci.22-21-09567.2002  1
2002 Khalkhali-Ellis Z, Handa RJ, Price RH, Adams BD, Callaghan JJ, Hendrix MJ. Androgen receptors in human synoviocytes and androgen regulation of interleukin 1beta (IL-1beta) induced IL-6 production: a link between hypoandrogenicity and rheumatoid arthritis? The Journal of Rheumatology. 29: 1843-6. PMID 12233876  1
2002 Jordan CL, Price RH, Handa RJ. Androgen receptor messenger RNA and protein in adult rat sciatic nerve: implications for site of androgen action. Journal of Neuroscience Research. 69: 509-18. PMID 12210844 DOI: 10.1002/Jnr.10324  1
2002 Solum DT, Handa RJ. Estrogen regulates the development of brain-derived neurotrophic factor mRNA and protein in the rat hippocampus. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 2650-9. PMID 11923430 DOI: 10.1523/Jneurosci.22-07-02650.2002  1
2002 Kuehl-Kovarik MC, Pouliot WA, Halterman GL, Handa RJ, Dudek FE, Partin KM. Episodic bursting activity and response to excitatory amino acids in acutely dissociated gonadotropin-releasing hormone neurons genetically targeted with green fluorescent protein. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 2313-22. PMID 11896170 DOI: 10.1523/Jneurosci.22-06-02313.2002  1
2001 Price RH, Butler CA, Webb P, Uht R, Kushner P, Handa RJ. A Splice Variant of Estrogen Receptor β Missing Exon 3 Displays Altered Subnuclear Localization and Capacity for Transcriptional Activation. Endocrinology. 142: 2039-2049. PMID 28204371 DOI: 10.1210/endo.142.5.8130  1
2001 Suzuki S, Solberg LC, Redei EE, Handa RJ. Prepro-thyrotropin releasing hormone 178-199 immunoreactivity is altered in the hypothalamus of the Wistar-Kyoto strain of rat. Brain Research. 913: 224-33. PMID 11549391 DOI: 10.1016/S0006-8993(01)02853-0  1
2001 Solum DT, Handa RJ. Localization of estrogen receptor alpha (ER alpha) in pyramidal neurons of the developing rat hippocampus. Brain Research. Developmental Brain Research. 128: 165-75. PMID 11412902 DOI: 10.1016/S0165-3806(01)00171-7  1
2001 Price RH, Butler CA, Webb P, Uht R, Kushner P, Handa RJ. A splice variant of estrogen receptor beta missing exon 3 displays altered subnuclear localization and capacity for transcriptional activation. Endocrinology. 142: 2039-49. PMID 11316771 DOI: 10.1210/Endo.142.5.8130  1
2000 Price RH, Lorenzon N, Handa RJ. Differential expression of estrogen receptor beta splice variants in rat brain: identification and characterization of a novel variant missing exon 4. Brain Research. Molecular Brain Research. 80: 260-8. PMID 11038261 DOI: 10.1016/S0169-328X(00)00135-2  1
2000 Khalkhali-Ellis Z, Seftor EA, Nieva DR, Handa RJ, Price RH, Kirschmann DA, Baragi VM, Sharma RV, Bhalla RC, Moore TL, Hendrix MJ. Estrogen and progesterone regulation of human fibroblast-like synoviocyte function in vitro: implications in rheumatoid arthritis. The Journal of Rheumatology. 27: 1622-31. PMID 10914842  1
2000 Price RH, Handa RJ. Expression of estrogen receptor-beta protein and mRNA in the cerebellum of the rat. Neuroscience Letters. 288: 115-8. PMID 10876074 DOI: 10.1016/S0304-3940(00)01221-0  1
1999 Nagahara AH, Handa RJ. Loss of nicotine-induced effects on locomotor activity in fetal alcohol-exposed rats. Neurotoxicology and Teratology. 21: 647-52. PMID 10560771 DOI: 10.1016/S0892-0362(99)00040-9  1
1999 Nagahara AH, Handa RJ. Fetal alcohol-exposed rats exhibit differential response to cholinergic drugs on a delay-dependent memory task. Neurobiology of Learning and Memory. 72: 230-43. PMID 10536100 DOI: 10.1006/Nlme.1999.3909  1
1999 Hileman SM, Handa RJ, Jackson GL. Distribution of estrogen receptor-beta messenger ribonucleic acid in the male sheep hypothalamus. Biology of Reproduction. 60: 1279-84. PMID 10330081 DOI: 10.1095/Biolreprod60.6.1279  1
1998 Wilson ME, Price RH, Handa RJ. Estrogen Receptor-β Messenger Ribonucleic Acid Expression in the Pituitary Gland* * This material is based on work supported by the NSF (96-04723; RJH) and USHPS National Research Scientist Award Predoctoral Fellowships F31-AA05395 (to M.E.W.) and F31-AA05461 (to R.H.P.). Endocrinology. 139: 5151-5156. PMID 28204235 DOI: 10.1210/endo.139.12.6354  1
1998 Wilson ME, Price RH, Handa RJ. Estrogen receptor-beta messenger ribonucleic acid expression in the pituitary gland. Endocrinology. 139: 5151-6. PMID 9832455 DOI: 10.1210/Endo.139.12.6354  1
1998 Wilson ME, Handa RJ. Direct actions of gonadal steroid hormones on FSH secretion and expression in the infantile female rat. The Journal of Steroid Biochemistry and Molecular Biology. 66: 71-8. PMID 9712414 DOI: 10.1016/S0960-0760(98)00007-7  1
1998 McGivern RF, Handa RJ, Raum WJ. Ethanol exposure during the last week of gestation in the rat: inhibition of the prenatal testosterone surge in males without long-term alterations in sex behavior. Neurotoxicology and Teratology. 20: 483-90. PMID 9697975 DOI: 10.1016/S0892-0362(98)00009-9  1
1998 Wilson ME, Handa RJ. Activin subunit, follistatin, and activin receptor gene expression in the prepubertal female rat pituitary. Biology of Reproduction. 59: 278-83. PMID 9687296 DOI: 10.1095/Biolreprod59.2.278  1
1998 McGivern RF, Ervin MG, McGeary J, Somes C, Handa RJ. Prenatal ethanol exposure induces a sexually dimorphic effect on daily water consumption in prepubertal and adult rats. Alcoholism, Clinical and Experimental Research. 22: 868-75. PMID 9660314  1
1998 McGivern RF, Ervin MG, McGeary J, Somes C, Handa RJ. Prenatal ethanol exposure induces a sexually dimorphic effect on daily water consumption in prepubertal and adult rats. Alcoholism: Clinical and Experimental Research. 22: 868-875. DOI: 10.1111/J.1530-0277.1998.Tb03881.X  1
1997 Wilson ME, Handa RJ. Gonadotropin secretion in infantile rats exposed to ethanol in utero. Alcohol (Fayetteville, N.Y.). 14: 497-501. PMID 9305466 DOI: 10.1016/S0741-8329(97)00037-2  1
1997 Yukhananov RY, Handa RJ. Estrogen alters proenkephalin RNAs in the paraventricular nucleus of the hypothalamus following stress. Brain Research. 764: 109-16. PMID 9295199 DOI: 10.1016/S0006-8993(97)00432-0  1
1997 Drengler SM, Handa RJ, Jones KJ. Effects of axotomy and testosterone on androgen receptor mRNA expression in hamster facial motoneurons. Experimental Neurology. 146: 374-9. PMID 9270047 DOI: 10.1006/Exnr.1997.6537  1
1997 Yukhananov RY, Handa RJ. Effect of morphine on proenkephalin gene expression in the rat brain. Brain Research Bulletin. 43: 349-56. PMID 9227847 DOI: 10.1016/S0361-9230(97)00019-1  1
1997 Li Y, McGivern RF, Nagahara AH, Handa RJ. Alterations in the estrogen sensitivity of hypothalamic proenkephalin mRNA expression with age and prenatal exposure to alcohol. Brain Research. Molecular Brain Research. 47: 215-22. PMID 9221919 DOI: 10.1016/S0169-328X(97)00050-8  1
1997 Nagahara AH, Handa RJ. Fetal alcohol exposure produces delay-dependent memory deficits in juvenile and adult rats. Alcoholism, Clinical and Experimental Research. 21: 710-5. PMID 9194928 DOI: 10.1111/J.1530-0277.1997.Tb03826.X  1
1997 Wilson ME, Handa RJ. Ontogeny of gene expression in the gonadotroph of the developing female rat. Biology of Reproduction. 56: 563-8. PMID 9116162 DOI: 10.1095/Biolreprod56.2.563  1
1997 Handa RJ, Hejna GM, Lorens SA. Androgen inhibits neurotransmitter turnover in the medial prefrontal cortex of the rat following exposure to a novel environment. Brain Research. 751: 131-8. PMID 9098576 DOI: 10.1016/S0006-8993(96)01394-7  1
1997 Nagahara AH, Handa RJ. Age-related changes in c-fos mRNA induction after open-field exposure in the rat brain. Neurobiology of Aging. 18: 45-55. PMID 8983032 DOI: 10.1016/S0197-4580(96)00166-2  1
1997 Handa RJ, Price R.H. J, Wilson ME. Steroid hormone receptors in the developing brain Biomedical Reviews. 7: 51-66. DOI: 10.14748/Bmr.V7.162  1
1996 McGivern RF, Fatayerji N, Handa RJ. Androstenedione synergizes with stress or prenatal drug exposure to retard fetal growth: role of IGF. Pharmacology, Biochemistry, and Behavior. 55: 549-57. PMID 8981585 DOI: 10.1016/S0091-3057(96)00249-3  1
1996 Yukhananov RY, Handa RJ. Alterations in kappa opioid receptor mRNA levels in the paraventricular nucleus of the hypothalamus by stress and sex steroids. Neuroreport. 7: 1690-4. PMID 8904783 DOI: 10.1097/00001756-199607080-00033  1
1996 Kerr JE, Beck SG, Handa RJ. Androgens selectively modulate C-fos messenger RNA induction in the rat hippocampus following novelty. Neuroscience. 74: 757-66. PMID 8884771 DOI: 10.1016/0306-4522(96)00219-9  1
1996 Drengler SM, Handa RJ, Jones KJ. Regulation of androgen receptor mRNA expression in hamster facial motoneurons: differential effects of non-aromatizable and aromatizable androgens. Brain Research. Molecular Brain Research. 41: 8-15. PMID 8883929 DOI: 10.1016/0169-328X(96)00060-5  1
1996 Handa RJ, George M, Gordon BH, Campbell DB, Lorens SA. Responses to novelty stress in female F344 rats: effects of age and d-fenfluramine treatment. Pharmacology, Biochemistry, and Behavior. 53: 641-7. PMID 8866967 DOI: 10.1016/0091-3057(95)02064-0  1
1996 McGivern RF, Handa RJ. Prenatal exposure to drugs of abuse: methodological considerations and effects on sexual differentiation. Nida Research Monograph. 164: 78-124. PMID 8809869  1
1996 Kerr JE, Beck SG, Handa RJ. Androgens modulate glucocorticoid receptor mRNA, but not mineralocorticoid receptor mRNA levels, in the rat hippocampus. Journal of Neuroendocrinology. 8: 439-47. PMID 8809674 DOI: 10.1046/J.1365-2826.1996.04735.X  1
1996 Handa RJ, Kerr JE, DonCarlos LL, McGivern RF, Hejna G. Hormonal regulation of androgen receptor messenger RNA in the medial preoptic area of the male rat. Brain Research. Molecular Brain Research. 39: 57-67. PMID 8804714 DOI: 10.1016/0169-328X(95)00353-T  1
1996 Pouliot WA, Handa RJ, Beck SG. Androgen modulates N-methyl-D-aspartate-mediated depolarization in CA1 hippocampal pyramidal cells. Synapse (New York, N.Y.). 23: 10-9. PMID 8723131 DOI: 10.1002/(SICI)1098-2396(199605)23:1<10::AID-SYN2>3.0.CO;2-K  1
1996 Drengler SM, Handa RJ, Jones KJ. Sex differences in androgen receptor mRNA levels and regulation in hamster facial motoneurons. Brain Research. Molecular Brain Research. 35: 131-8. PMID 8717348 DOI: 10.1016/0169-328X(95)00197-Z  1
1996 Fatayerji N, Engelmann GL, Myers T, Handa RJ. In utero exposure to ethanol alters mRNA for insulin-like growth factors and insulin-like growth factor-binding proteins in placenta and lung of fetal rats. Alcoholism, Clinical and Experimental Research. 20: 94-100. PMID 8651471 DOI: 10.1111/J.1530-0277.1996.Tb01051.X  1
1995 Nagahara AH, Handa RJ. Fetal alcohol exposure alters the induction of immediate early gene mRNA in the rat prefrontal cortex after an alternation task. Alcoholism, Clinical and Experimental Research. 19: 1389-97. PMID 8749800 DOI: 10.1111/J.1530-0277.1995.Tb00997.X  1
1995 Wilson ME, Marshall MT, Bollnow MR, McGivern RF, Handa RJ. Gonadotropin-releasing hormone mRNA and gonadotropin beta-subunit mRNA expression in the adult female rat exposed to ethanol in utero. Alcoholism, Clinical and Experimental Research. 19: 1211-8. PMID 8561293 DOI: 10.1111/J.1530-0277.1995.Tb01603.X  1
1995 Schulz MK, McNulty JA, Handa RJ, Hogan TP, Tillotson GL, Shaw PL, Zimmer J, Castro AJ. Fetal neocortical transplants grafted into neocortical lesion cavities made in newborn rats: an analysis of transplant integration with the host brain. Cell Transplantation. 4: 123-32. PMID 7728326 DOI: 10.1016/0963-6897(94)00044-K  1
1995 Kus L, Handa RJ, Sanderson JJ, Kerr JE, Beitz AJ. Distribution of NMDAR1 receptor subunit mRNA and [125I]MK-801 binding in the hypothalamus of intact, castrate and castrate-DHTP treated male rats. Brain Research. Molecular Brain Research. 28: 55-60. PMID 7707878 DOI: 10.1016/0169-328X(94)00179-I  1
1995 Kerr JE, Allore RJ, Beck SG, Handa RJ. Distribution and hormonal regulation of androgen receptor (AR) and AR messenger ribonucleic acid in the rat hippocampus. Endocrinology. 136: 3213-21. PMID 7628354 DOI: 10.1210/Endo.136.8.7628354  1
1995 McGivern RF, McGeary J, Robeck S, Cohen S, Handa RJ. Loss of reproductive competence at an earlier age in female rats exposed prenatally to ethanol. Alcoholism, Clinical and Experimental Research. 19: 427-33. PMID 7625578 DOI: 10.1111/J.1530-0277.1995.Tb01526.X  1
1995 O'Keefe JA, Li Y, Burgess LH, Handa RJ. Estrogen receptor mRNA alterations in the developing rat hippocampus. Brain Research. Molecular Brain Research. 30: 115-24. PMID 7609632 DOI: 10.1016/0169-328X(94)00284-L  1
1995 McGivern RF, Hermans RH, Handa RJ, Longo LD. Plasma testosterone surge and luteinizing hormone beta (LH-beta) following parturition: lack of association in the male rat. European Journal of Endocrinology / European Federation of Endocrine Societies. 133: 366-74. PMID 7581956 DOI: 10.1530/eje.0.1330366  1
1995 Kus L, Handa RJ, Hautman JM, Beitz AJ. Castration increases [125I]MK801 binding in the hippocampus of male rats. Brain Research. 683: 270-4. PMID 7552365 DOI: 10.1016/0006-8993(95)00384-3  1
1994 Bingaman EW, Magnuson DJ, Gray TS, Handa RJ. Androgen inhibits the increases in hypothalamic corticotropin-releasing hormone (CRH) and CRH-immunoreactivity following gonadectomy. Neuroendocrinology. 59: 228-34. PMID 8159272 DOI: 10.1159/000126663  1
1994 Handa RJ, Nunley KM, Lorens SA, Louie JP, McGivern RF, Bollnow MR. Androgen regulation of adrenocorticotropin and corticosterone secretion in the male rat following novelty and foot shock stressors. Physiology & Behavior. 55: 117-24. PMID 8140154 DOI: 10.1016/0031-9384(94)90018-3  1
1994 Ionides SP, Weiss MG, Angelopoulos M, Myers TF, Handa RJ. Plasma beta-endorphin concentrations and analgesia-muscle relaxation in the newborn infant supported by mechanical ventilation. The Journal of Pediatrics. 125: 113-6. PMID 8021759 DOI: 10.1016/S0022-3476(94)70136-9  1
1994 Schulz MK, Handa RJ, Tillotson GL, Castro AJ. Expression of c-fos mRNA and c-fos protein in neocortical transplants placed into excitotoxin-induced lesions in adult rats. Experimental Neurology. 129: 321-9. PMID 7957744 DOI: 10.1006/Exnr.1994.1174  1
1994 DonCarlos LL, Handa RJ. Developmental profile of estrogen receptor mRNA in the preoptic area of male and female neonatal rats. Brain Research. Developmental Brain Research. 79: 283-9. PMID 7955327 DOI: 10.1016/0165-3806(94)90133-3  1
1994 Kus L, Handa RJ, McNulty JA. Glutamate inhibition of the adrenergic-stimulated production of melatonin in rat pineal gland in vitro. Journal of Neurochemistry. 62: 2241-5. PMID 7910630 DOI: 10.1046/J.1471-4159.1994.62062241.X  1
1994 Ros SP, Reynolds SL, Bhisitkul DM, Ionides SP, Handa RJ. Plasma beta-endorphin levels and childhood intussusception. The Journal of Emergency Medicine. 12: 767-9. PMID 7884194 DOI: 10.1016/0736-4679(94)90481-2  1
1994 Bingaman EW, Baeckman LM, Yracheta JM, Handa RJ, Gray TS. Localization of androgen receptor within peptidergic neurons of the rat forebrain. Brain Research Bulletin. 35: 379-82. PMID 7850490 DOI: 10.1016/0361-9230(94)90117-1  1
1994 Handa RJ, Burgess LH, Kerr JE, O'Keefe JA. Gonadal steroid hormone receptors and sex differences in the hypothalamo-pituitary-adrenal axis. Hormones and Behavior. 28: 464-76. PMID 7729815 DOI: 10.1006/Hbeh.1994.1044  1
1993 Burgess LH, Handa RJ. Estrogen-induced alterations in the regulation of mineralocorticoid and glucocorticoid receptor messenger RNA expression in the female rat anterior pituitary gland and brain. Molecular and Cellular Neurosciences. 4: 191-8. PMID 19912922 DOI: 10.1006/Mcne.1993.1023  1
1993 Burgess LH, Handa RJ. Hormonal regulation of androgen receptor mRNA in the brain and anterior pituitary gland of the male rat. Brain Research. Molecular Brain Research. 19: 31-8. PMID 8361343 DOI: 10.1016/0169-328X(93)90145-F  1
1993 Hammer RP, Bogic L, Handa RJ. Estrogenic regulation of proenkephalin mRNA expression in the ventromedial hypothalamus of the adult male rat. Brain Research. Molecular Brain Research. 19: 129-34. PMID 8361335 DOI: 10.1016/0169-328X(93)90157-K  1
1993 Handa RJ, Cross MK, George M, Gordon BH, Burgess LH, Cabrera TM, Hata N, Campbell DB, Lorens SA. Neuroendocrine and neurochemical responses to novelty stress in young and old male F344 rats: effects of d-fenfluramine treatment. Pharmacology, Biochemistry, and Behavior. 46: 101-9. PMID 8255900 DOI: 10.1016/0091-3057(93)90324-M  1
1993 O'Keefe JA, Pedersen EB, Castro AJ, Handa RJ. The ontogeny of estrogen receptors in heterochronic hippocampal and neocortical transplants demonstrates an intrinsic developmental program. Brain Research. Developmental Brain Research. 75: 105-12. PMID 8222204 DOI: 10.1016/0165-3806(93)90069-M  1
1993 Handa RJ, Nunley KM, Bollnow MR. Induction of c-fos mRNA in the brain and anterior pituitary gland by a novel environment. Neuroreport. 4: 1079-82. PMID 8219031  1
1993 McGivern RF, Handa RJ, Redei E. Decreased postnatal testosterone surge in male rats exposed to ethanol during the last week of gestation. Alcoholism, Clinical and Experimental Research. 17: 1215-22. PMID 8116834 DOI: 10.1111/J.1530-0277.1993.Tb05232.X  1
1993 Kus L, Handa RJ, McNulty JA. Characterization of a [3H]glutamate binding site in rat pineal gland: enhanced affinity following superior cervical ganglionectomy. Journal of Pineal Research. 14: 39-44. PMID 8097770 DOI: 10.1111/J.1600-079X.1993.Tb00483.X  1
1992 Pedersen EB, O'Keefe JA, Handa RJ, Castro AJ. Estrogen receptors are present in neocortical transplants. Journal of Neural Transplantation & Plasticity. 3: 135-8. PMID 1515481 DOI: 10.1155/Np.1992.135  1
1992 McGivern RF, Raum WJ, Handa RJ, Sokol RZ. Comparison of two weeks versus one week of prenatal ethanol exposure in the rat on gonadal organ weights, sperm count, and onset of puberty. Neurotoxicology and Teratology. 14: 351-8. PMID 1454044 DOI: 10.1016/0892-0362(92)90042-9  1
1992 Burgess LH, Handa RJ. Chronic estrogen-induced alterations in adrenocorticotropin and corticosterone secretion, and glucocorticoid receptor-mediated functions in female rats. Endocrinology. 131: 1261-9. PMID 1324155 DOI: 10.1210/Endo.131.3.1324155  1
1991 Handa RJ, Rodriguez EW. A characterization of estrogen's influence on anterior pituitary androgen receptor: effect of bromocriptine treatment. Neuroendocrinology. 53: 12-9. PMID 2046857 DOI: 10.1159/000125691  1
1991 Handa RJ, Rodriguez EW, Fox CA, Jacobson CD. Characterization and distribution of estrogen receptors in the diencephalon of the gray short-tailed opossum. Brain Research. 539: 6-10. PMID 2015504 DOI: 10.1016/0006-8993(91)90680-T  1
1991 Fox CA, Ross LR, Handa RJ, Jacobson CD. Localization of cells containing estrogen receptor-like immunoreactivity in the Brazilian opossum brain. Brain Research. 546: 96-105. PMID 1855151 DOI: 10.1016/0006-8993(91)91163-U  1
1991 Clancy J, Petrovic LM, Gordon BH, Handa RJ, Campbell DB, Lorens SA. Effects of subchronic d-fenfluramine on splenic immune functions in young and old male and female Fischer 344 rats. International Journal of Immunopharmacology. 13: 1203-12. PMID 1814854 DOI: 10.1016/0192-0561(91)90171-3  1
1990 Lorens SA, Hata N, Handa RJ, Van de Kar LD, Guschwan M, Goral J, Lee JM, Hamilton ME, Bethea CL, Clancy J. Neurochemical, endocrine and immunological responses to stress in young and old Fischer 344 male rats. Neurobiology of Aging. 11: 139-50. PMID 2348902 DOI: 10.1016/0197-4580(90)90047-4  1
1990 McNulty JA, Relfson M, Fox LM, Fox LM, Kus L, Handa RJ, Schneider GB. Circadian analysis of mononuclear cells in the rat following pinealectomy and superior cervical ganglionectomy. Brain, Behavior, and Immunity. 4: 292-307. PMID 2092865 DOI: 10.1016/0889-1591(90)90033-M  1
1990 O'Keefe JA, Handa RJ. Transient elevation of estrogen receptors in the neonatal rat hippocampus. Brain Research. Developmental Brain Research. 57: 119-27. PMID 2090365 DOI: 10.1016/0165-3806(90)90191-Z  1
1989 Toyooka KR, Connolly PB, Handa RJ, Resko JA. Ontogeny of androgen receptors in fetal guinea pig brain. Biology of Reproduction. 41: 204-12. PMID 2804213 DOI: 10.1095/Biolreprod41.2.204  1
1989 Roselli CE, Handa RJ, Resko JA. Quantitative distribution of nuclear androgen receptors in microdissected areas of the rat brain. Neuroendocrinology. 49: 449-53. PMID 2725839 DOI: 10.1159/000125151  1
1989 Handa RJ, Resko JA. Alpha-adrenergic regulation of androgen receptor concentration in the preoptic area of the rat. Brain Research. 483: 312-20. PMID 2539892 DOI: 10.1016/0006-8993(89)90175-3  1
1988 Connolly PB, Handa RJ, Resko JA. Progesterone modulation of androgen receptors in the brain and pituitary of male guinea pigs. Endocrinology. 122: 2547-53. PMID 3371256 DOI: 10.1210/Endo-122-6-2547  1
1988 Handa RJ, Connolly PB, Resko JA. Ontogeny of cytosolic androgen receptors in the brain of the fetal rhesus monkey. Endocrinology. 122: 1890-6. PMID 3359967 DOI: 10.1210/Endo-122-5-1890  1
1988 Handa RJ, Roselli CE, Resko JA. Distribution of androgen receptor in microdissected brain areas of the female baboon (Papio cynocephalus). Brain Research. 445: 111-6. PMID 3259151 DOI: 10.1016/0006-8993(88)91079-7  1
1988 McGivern RF, Roselli CE, Handa RJ. Perinatal aromatase activity in male and female rats: effect of prenatal alcohol exposure. Alcoholism, Clinical and Experimental Research. 12: 769-72. PMID 3064636 DOI: 10.1111/J.1530-0277.1988.Tb01342.X  1
1988 Handa RJ, Resko JA. Effects of gonadectomy and hormone replacement on steroid hormone receptors and 5 alpha-reductase activity in pituitaries of male rhesus macaques. The Journal of Clinical Endocrinology and Metabolism. 66: 1251-8. PMID 2836472 DOI: 10.1210/Jcem-66-6-1251  1
1987 Handa RJ, Stadelman HL, Resko JA. Effect of estrogen on androgen receptor dynamics in female rat pituitary. Endocrinology. 121: 84-9. PMID 3496212 DOI: 10.1210/Endo-121-1-84  1
1987 Handa RJ, Roselli CE, Horton L, Resko JA. The quantitative distribution of cytosolic androgen receptors in microdissected areas of the male rat brain: effects of estrogen treatment. Endocrinology. 121: 233-40. PMID 3496208 DOI: 10.1210/Endo-121-1-233  1
1986 Condon TP, Handa RJ, Gorski RA, Sawyer CH, Whitmoyer DI. Ovarian steroid modulation of norepinephrine action on luteinizing hormone release. Analogous effects in male and female rats. Neuroendocrinology. 43: 550-6. PMID 3748310 DOI: 10.1159/000124581  1
1986 Resko JA, Stadelman HL, Handa RJ. Control of 5 alpha-reduction of testosterone in neuroendocrine tissues of female rats. Biology of Reproduction. 34: 870-7. PMID 3730482 DOI: 10.1095/Biolreprod34.5.870  1
1986 Handa RJ, Reid DL, Resko JA. Androgen receptors in brain and pituitary of female rats: cyclic changes and comparisons with the male. Biology of Reproduction. 34: 293-303. PMID 3485449 DOI: 10.1095/Biolreprod34.2.293  1
1986 Handa RJ, Condon TP, Whitmoyer DI, Gorski RA. Gonadotropin secretion following intraventricular norepinephrine infusion into neonatally androgenized female rats. Neuroendocrinology. 43: 269-72. PMID 3090462 DOI: 10.1159/000124539  1
1986 Handa RJ, Hines M, Schoonmaker JN, Shryne JE, Gorski RA. Evidence that serotonin is involved in the sexually dimorphic development of the preoptic area in the rat brain. Brain Research. 395: 278-82. PMID 2946361 DOI: 10.1016/0165-3806(86)90120-3  1
1985 Handa RJ, Corbier P, Shryne JE, Schoonmaker JN, Gorski RA. Differential effects of the perinatal steroid environment on three sexually dimorphic parameters of the rat brain. Biology of Reproduction. 32: 855-64. PMID 3924134 DOI: 10.1095/biolreprod32.4.855  1
1985 Handa RJ, Gorski RA. Alterations in the onset of ovulatory failure and gonadotropin secretion following steroid administration to lightly androgenized female rats. Biology of Reproduction. 32: 248-56. PMID 3921068 DOI: 10.1095/Biolreprod32.2.248  1
1985 Handa RJ, Nass TE, Gorski RA. Proestrous hormonal changes preceding the onset of ovulatory failure in lightly androgenized female rats. Biology of Reproduction. 32: 232-40. PMID 3921067 DOI: 10.1095/Biolreprod32.2.232  1
1985 Handa RJ, McGivern RF, Noble ES, Gorski RA. Exposure to alcohol in utero alters the adult patterns of luteinizing hormone secretion in male and female rats. Life Sciences. 37: 1683-90. PMID 3903412 DOI: 10.1016/0024-3205(85)90295-4  1
1985 Simerly RB, Swanson LW, Handa RJ, Gorski RA. Influence of perinatal androgen on the sexually dimorphic distribution of tyrosine hydroxylase-immunoreactive cells and fibers in the anteroventral periventricular nucleus of the rat. Neuroendocrinology. 40: 501-10. PMID 2861581 DOI: 10.1159/000124122  1
1982 Handa RJ, Gorski RA. Pharmacological reinitiation of ovulation in lightly androgenized rats Anatomical Record. 202: 74a-75a.  1
1980 Handa RJ, Chiasson RB. Comparative effects of three goitrogenic treatments on White Leghorn chickens. Avian Diseases. 24: 916-29. PMID 6168257  1
1980 Handa RJ, Chiasson RB. Comparative effects of goitrogenic treatments on white leghorn chickens Federation Proceedings. 39: 3575.  1
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