Daniel Geschwind - Publications

University of California, Los Angeles, Los Angeles, CA 
Autism, Handedness, Development, Neurodegenerative Diseases, Microarrays

255 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Guo MG, Reynolds DL, Ang CE, Liu Y, Zhao Y, Donohue LKH, Siprashvili Z, Yang X, Yoo Y, Mondal S, Hong A, Kain J, Meservey L, Fabo T, Elfaki I, ... ... Geschwind DH, et al. Integrative analyses highlight functional regulatory variants associated with neuropsychiatric diseases. Nature Genetics. PMID 37857935 DOI: 10.1038/s41588-023-01533-5  0.346
2023 Warrier V, Stauffer EM, Huang QQ, Wigdor EM, Slob EAW, Seidlitz J, Ronan L, Valk SL, Mallard TT, Grotzinger AD, Romero-Garcia R, Baron-Cohen S, Geschwind DH, Lancaster MA, Murray GK, et al. Genetic insights into human cortical organization and development through genome-wide analyses of 2,347 neuroimaging phenotypes. Nature Genetics. PMID 37592024 DOI: 10.1038/s41588-023-01475-y  0.661
2023 Cirnigliaro M, Chang TS, Arteaga SA, Pérez-Cano L, Ruzzo EK, Gordon A, Bicks LK, Jung JY, Lowe JK, Wall DP, Geschwind DH. The contributions of rare inherited and polygenic risk to ASD in multiplex families. Proceedings of the National Academy of Sciences of the United States of America. 120: e2215632120. PMID 37506195 DOI: 10.1073/pnas.2215632120  0.326
2023 Guo Q, Wu S, Geschwind DH. Characterization of gene regulatory elements in human fetal cortical development: Enhancing our understanding of neurodevelopmental disorders and evolution. Developmental Neuroscience. PMID 37231806 DOI: 10.1159/000530929  0.35
2023 Wen C, Margolis M, Dai R, Zhang P, Przytycki PF, Vo DD, Bhattacharya A, Kim M, Matoba N, Tsai E, Hoh C, Jiao C, Aygun N, Walker RL, Chatzinakos C, ... ... Geschwind DH, et al. Cross-ancestry, cell-type-informed atlas of gene, isoform, and splicing regulation in the developing human brain. Medrxiv : the Preprint Server For Health Sciences. PMID 36945630 DOI: 10.1101/2023.03.03.23286706  0.779
2023 Wamsley B, Bicks L, Cheng Y, Kawaguchi R, Quintero D, Grundman J, Liu J, Xiao S, Hawken N, Margolis M, Mazariegos S, Geschwind DH. Molecular cascades and cell-type specific signatures in ASD revealed by single cell genomics. Biorxiv : the Preprint Server For Biology. PMID 36945369 DOI: 10.1101/2023.03.10.530869  0.401
2023 Lafferty MJ, Aygün N, Patel NK, Krupa O, Liang D, Wolter JM, Geschwind DH, de la Torre-Ubieta L, Stein JL. MicroRNA-eQTLs in the developing human neocortex link miR-4707-3p expression to brain size. Elife. 12. PMID 36629315 DOI: 10.7554/eLife.79488  0.481
2022 Gandal MJ, Haney JR, Wamsley B, Yap CX, Parhami S, Emani PS, Chang N, Chen GT, Hoftman GD, de Alba D, Ramaswami G, Hartl CL, Bhattacharya A, Luo C, Jin T, ... ... Geschwind DH, et al. Broad transcriptomic dysregulation occurs across the cerebral cortex in ASD. Nature. PMID 36323788 DOI: 10.1038/s41586-022-05377-7  0.824
2022 Chen GT, Geschwind DH. Challenges and Opportunities for Precision Medicine in Neurodevelopmental Disorders. Advanced Drug Delivery Reviews. 114564. PMID 36183905 DOI: 10.1016/j.addr.2022.114564  0.331
2022 Hoffman GE, Jaffe AE, Gandal MJ, Collado-Torres L, Sieberts SK, Devlin B, Geschwind DH, Weinberger DR, Roussos P. Comment on: What genes are differentially expressed in individuals with schizophrenia? A systematic review. Molecular Psychiatry. PMID 36123423 DOI: 10.1038/s41380-022-01781-7  0.611
2022 Berto S, Treacher AH, Caglayan E, Luo D, Haney JR, Gandal MJ, Geschwind DH, Montillo AA, Konopka G. Association between resting-state functional brain connectivity and gene expression is altered in autism spectrum disorder. Nature Communications. 13: 3328. PMID 35680911 DOI: 10.1038/s41467-022-31053-5  0.777
2021 Krebs MD, Themudo GE, Benros ME, Mors O, Børglum AD, Hougaard D, Mortensen PB, Nordentoft M, Gandal MJ, Fan CC, Geschwind DH, Schork AJ, Werge T, Thompson WK. Associations between patterns in comorbid diagnostic trajectories of individuals with schizophrenia and etiological factors. Nature Communications. 12: 6617. PMID 34785645 DOI: 10.1038/s41467-021-26903-7  0.599
2021 Vlasova RM, Iosif AM, Ryan AM, Funk LH, Murai T, Chen S, Lesh TA, Rowland DJ, Bennett J, Hogrefe CE, Maddock RJ, Gandal MJ, Geschwind DH, Schumann CM, Van de Water J, et al. Maternal immune activation during pregnancy alters postnatal brain growth and cognitive development in nonhuman primate offspring. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 34607967 DOI: 10.1523/JNEUROSCI.0378-21.2021  0.592
2021 López-Aranda MF, Chattopadhyay I, Boxx GM, Fraley ER, Silva TK, Zhou M, Phan M, Herrera I, Taloma S, Mandanas R, Bach K, Gandal M, Geschwind DH, Cheng G, Rzhetsky A, et al. Postnatal immune activation causes social deficits in a mouse model of tuberous sclerosis: Role of microglia and clinical implications. Science Advances. 7: eabf2073. PMID 34533985 DOI: 10.1126/sciadv.abf2073  0.556
2021 Aygün N, Elwell AL, Liang D, Lafferty MJ, Cheek KE, Courtney KP, Mory J, Hadden-Ford E, Krupa O, de la Torre-Ubieta L, Geschwind DH, Love MI, Stein JL. Brain-trait-associated variants impact cell-type-specific gene regulation during neurogenesis. American Journal of Human Genetics. PMID 34416157 DOI: 10.1016/j.ajhg.2021.07.011  0.59
2021 Eyring KW, Geschwind DH. Three decades of ASD genetics: Building a foundation for neurobiological understanding and treatment. Human Molecular Genetics. PMID 34313757 DOI: 10.1093/hmg/ddab176  0.374
2021 Hartl CL, Ramaswami G, Pembroke WG, Muller S, Pintacuda G, Saha A, Parsana P, Battle A, Lage K, Geschwind DH. Coexpression network architecture reveals the brain-wide and multiregional basis of disease susceptibility. Nature Neuroscience. PMID 34294919 DOI: 10.1038/s41593-021-00887-5  0.324
2021 Hu B, Won H, Mah W, Park RB, Kassim B, Spiess K, Kozlenkov A, Crowley CA, Pochareddy S, Li Y, Dracheva S, Sestan N, Akbarian S, Geschwind DH. Neuronal and glial 3D chromatin architecture informs the cellular etiology of brain disorders. Nature Communications. 12: 3968. PMID 34172755 DOI: 10.1038/s41467-021-24243-0  0.369
2021 Lawrence KE, Hernandez LM, Fuster E, Padgaonkar NT, Patterson G, Jung J, Okada NJ, Lowe JK, Hoekstra JN, Jack A, Aylward E, Gaab N, Van Horn JD, Bernier RA, McPartland JC, ... ... Geschwind DH, et al. Impact of autism genetic risk on brain connectivity: a mechanism for the female protective effect. Brain : a Journal of Neurology. PMID 34050743 DOI: 10.1093/brain/awab204  0.317
2021 Liang D, Elwell AL, Aygün N, Krupa O, Wolter JM, Kyere FA, Lafferty MJ, Cheek KE, Courtney KP, Yusupova M, Garrett ME, Ashley-Koch A, Crawford GE, Love MI, de la Torre-Ubieta L, ... Geschwind DH, et al. Cell-type-specific effects of genetic variation on chromatin accessibility during human neuronal differentiation. Nature Neuroscience. PMID 34017130 DOI: 10.1038/s41593-021-00858-w  0.602
2021 Gordon A, Yoon SJ, Tran SS, Makinson CD, Park JY, Andersen J, Valencia AM, Horvath S, Xiao X, Huguenard JR, Pașca SP, Geschwind DH. Long-term maturation of human cortical organoids matches key early postnatal transitions. Nature Neuroscience. PMID 33619405 DOI: 10.1038/s41593-021-00802-y  0.313
2021 Gandal MJ, Geschwind DH. Polygenicity in Psychiatry-Like It or Not, We Have to Understand It. Biological Psychiatry. 89: 2-4. PMID 33272361 DOI: 10.1016/j.biopsych.2020.10.002  0.588
2020 Page NF, Gandal MJ, Estes ML, Cameron S, Buth J, Parhami S, Ramaswami G, Murray K, Amaral DG, Van de Water JA, Schumann CM, Carter CS, Bauman MD, McAllister AK, Geschwind DH. Alterations in Retrotransposition, Synaptic Connectivity, and Myelination Implicated by Transcriptomic Changes Following Maternal Immune Activation in Nonhuman Primates. Biological Psychiatry. PMID 33386132 DOI: 10.1016/j.biopsych.2020.10.016  0.61
2020 Ramaswami G, Won H, Gandal MJ, Haney J, Wang JC, Wong CCY, Sun W, Prabhakar S, Mill J, Geschwind DH. Integrative genomics identifies a convergent molecular subtype that links epigenomic with transcriptomic differences in autism. Nature Communications. 11: 4873. PMID 32978376 DOI: 10.1038/s41467-020-18526-1  0.717
2020 Wamsley B, Geschwind DH. Functional genomics links genetic origins to pathophysiology in neurodegenerative and neuropsychiatric disease. Current Opinion in Genetics & Development. 65: 117-125. PMID 32634676 DOI: 10.1016/j.gde.2020.05.032  0.318
2020 Seidlitz J, Nadig A, Liu S, Bethlehem RAI, Vértes PE, Morgan SE, Váša F, Romero-Garcia R, Lalonde FM, Clasen LS, Blumenthal JD, Paquola C, Bernhardt B, Wagstyl K, Polioudakis D, ... ... Geschwind DH, et al. Transcriptomic and cellular decoding of regional brain vulnerability to neurogenetic disorders. Nature Communications. 11: 3358. PMID 32620757 DOI: 10.1038/S41467-020-17051-5  0.369
2020 Walker RL, Ramaswami G, Hartl C, Mancuso N, Gandal MJ, de la Torre-Ubieta L, Pasaniuc B, Stein JL, Geschwind DH. Genetic Control of Expression and Splicing in Developing Human Brain Informs Disease Mechanisms. Cell. 181: 745. PMID 32359439 DOI: 10.1016/j.cell.2020.04.016  0.709
2020 Walker RL, Ramaswami G, Hartl C, Mancuso N, Gandal MJ, Torre-Ubieta L, Pasaniuc B, Stein JL, Geschwind DH. Genetic Control of Expression and Splicing in Developing Human Brain Informs Disease Mechanisms. Cell. 181: 484. PMID 32302575 DOI: 10.1016/j.cell.2020.04.003  0.709
2019 Gandal MJ, Haney JR, Parikshak NN, Leppa V, Ramaswami G, Hartl C, Schork AJ, Appadurai V, Buil A, Werge TM, Liu C, White KP, Geschwind DH. Shared Molecular Neuropathology Across Major Psychiatric Disorders Parallels Polygenic Overlap. Focus (American Psychiatric Publishing). 17: 66-72. PMID 32015716 DOI: 10.1176/appi.focus.17103  0.754
2019 Gordon A, Forsingdal A, Klewe IV, Nielsen J, Didriksen M, Werge T, Geschwind DH. Transcriptomic networks implicate neuronal energetic abnormalities in three mouse models harboring autism and schizophrenia-associated mutations. Molecular Psychiatry. PMID 31705054 DOI: 10.1038/s41380-019-0576-0  0.424
2019 Walker RL, Ramaswami G, Hartl C, Mancuso N, Gandal MJ, de la Torre-Ubieta L, Pasaniuc B, Stein JL, Geschwind DH. Genetic Control of Expression and Splicing in Developing Human Brain Informs Disease Mechanisms. Cell. 179: 750-771.e22. PMID 31626773 DOI: 10.1016/J.Cell.2019.09.021  0.78
2019 Sanders SJ, Sahin M, Hostyk J, Thurm A, Jacquemont S, Avillach P, Douard E, Martin CL, Modi ME, Moreno-De-Luca A, Raznahan A, Anticevic A, Dolmetsch R, Feng G, Geschwind DH, et al. A framework for the investigation of rare genetic disorders in neuropsychiatry. Nature Medicine. PMID 31548702 DOI: 10.1038/S41591-019-0581-5  0.684
2019 Forsyth JK, Nachun D, Gandal MJ, Geschwind DH, Anderson AE, Coppola G, Bearden CE. Synaptic and Gene Regulatory Mechanisms in Schizophrenia, Autism, and 22q11.2 Copy Number Variant-Mediated Risk for Neuropsychiatric Disorders. Biological Psychiatry. PMID 31500805 DOI: 10.1016/J.Biopsych.2019.06.029  0.662
2019 Shi G, Xing L, Wu D, Bhattacharyya BJ, Jones CR, McMahon T, Chong SYC, Chen JA, Coppola G, Geschwind D, Krystal A, Ptáček LJ, Fu YH. A Rare Mutation of β-Adrenergic Receptor Affects Sleep/Wake Behaviors. Neuron. PMID 31473062 DOI: 10.1016/J.Neuron.2019.07.026  0.515
2019 Lee C, Kang EY, Gandal MJ, Eskin E, Geschwind DH. Profiling allele-specific gene expression in brains from individuals with autism spectrum disorder reveals preferential minor allele usage. Nature Neuroscience. 22: 1521-1532. PMID 31455884 DOI: 10.1038/S41593-019-0461-9  0.68
2019 Ruzzo EK, Pérez-Cano L, Jung JY, Wang LK, Kashef-Haghighi D, Hartl C, Singh C, Xu J, Hoekstra JN, Leventhal O, Leppä VM, Gandal MJ, Paskov K, Stockham N, Polioudakis D, ... ... Geschwind DH, et al. Inherited and De Novo Genetic Risk for Autism Impacts Shared Networks. Cell. 178: 850-866.e26. PMID 31398340 DOI: 10.1016/J.Cell.2019.07.015  0.697
2019 Polioudakis D, de la Torre-Ubieta L, Langerman J, Elkins AG, Shi X, Stein JL, Vuong CK, Nichterwitz S, Gevorgian M, Opland CK, Lu D, Connell W, Ruzzo EK, Lowe JK, Hadzic T, ... ... Geschwind DH, et al. A Single-Cell Transcriptomic Atlas of Human Neocortical Development during Mid-gestation. Neuron. PMID 31303374 DOI: 10.1016/J.Neuron.2019.06.011  0.536
2019 Wong CCY, Smith RG, Hannon E, Ramaswami G, Parikshak NN, Assary E, Troakes C, Poschmann J, Schalkwyk LC, Sun W, Prabhakar S, Geschwind DH, Mill J. Genome-wide DNA methylation profiling identifies convergent molecular signatures associated with idiopathic and syndromic autism in post-mortem human brain tissue. Human Molecular Genetics. 28: 2201-2211. PMID 31220268 DOI: 10.1093/Hmg/Ddz052  0.718
2019 Won H, Huang J, Opland CK, Hartl CL, Geschwind DH. Human evolved regulatory elements modulate genes involved in cortical expansion and neurodevelopmental disease susceptibility. Nature Communications. 10: 2396. PMID 31160561 DOI: 10.1038/s41467-019-10248-3  0.323
2019 Sharon G, Cruz NJ, Kang DW, Gandal MJ, Wang B, Kim YM, Zink EM, Casey CP, Taylor BC, Lane CJ, Bramer LM, Isern NG, Hoyt DW, Noecker C, Sweredoski MJ, ... ... Geschwind DH, et al. Human Gut Microbiota from Autism Spectrum Disorder Promote Behavioral Symptoms in Mice. Cell. 177: 1600-1618.e17. PMID 31150625 DOI: 10.1016/J.Cell.2019.05.004  0.64
2019 Chen Z, Chen JA, Shatunov A, Jones AR, Kravitz SN, Huang AY, Lawrence L, Lowe JK, Lewis CM, Payan CAM, Lieb W, Franke A, Deloukas P, Amouyel P, Tzourio C, ... ... Geschwind DH, et al. Genome-wide survey of copy number variants finds MAPT duplications in progressive supranuclear palsy. Movement Disorders : Official Journal of the Movement Disorder Society. PMID 31059154 DOI: 10.1002/Mds.27702  0.555
2019 Sullivan PF, Geschwind DH. Defining the Genetic, Genomic, Cellular, and Diagnostic Architectures of Psychiatric Disorders. Cell. 177: 162-183. PMID 30901538 DOI: 10.1016/j.cell.2019.01.015  0.337
2019 Prohaska A, Racimo F, Schork AJ, Sikora M, Stern AJ, Ilardo M, Allentoft ME, Folkersen L, Buil A, Moreno-Mayar JV, Korneliussen T, Geschwind D, Ingason A, Werge T, Nielsen R, et al. Human Disease Variation in the Light of Population Genomics. Cell. 177: 115-131. PMID 30901534 DOI: 10.1016/J.Cell.2019.01.052  0.365
2019 Grove J, Ripke S, Als TD, Mattheisen M, Walters RK, Won H, Pallesen J, Agerbo E, Andreassen OA, Anney R, Awashti S, Belliveau R, Bettella F, Buxbaum JD, Bybjerg-Grauholm J, ... ... Geschwind DH, et al. Identification of common genetic risk variants for autism spectrum disorder. Nature Genetics. PMID 30804558 DOI: 10.1038/S41588-019-0344-8  0.347
2019 Schork AJ, Won H, Appadurai V, Nudel R, Gandal M, Delaneau O, Revsbech Christiansen M, Hougaard DM, Bækved-Hansen M, Bybjerg-Grauholm J, Giørtz Pedersen M, Agerbo E, Bøcker Pedersen C, Neale BM, Daly MJ, ... ... Geschwind DH, et al. A genome-wide association study of shared risk across psychiatric disorders implicates gene regulation during fetal neurodevelopment. Nature Neuroscience. PMID 30692689 DOI: 10.1038/S41593-018-0320-0  0.685
2019 Forsyth J, Nachun D, Gandal M, Geschwind D, Anderson A, Coppola G, Bearden C. T55SYNAPTIC AND GENE REGULATORY MECHANISMS IN SCHIZOPHRENIA, AUTISM, AND 22Q11.2 CNV MEDIATED RISK FOR NEUROPSYCHIATRIC DISORDERS European Neuropsychopharmacology. 29: S244-S245. DOI: 10.1016/J.Euroneuro.2019.08.254  0.675
2019 Haney J, Parhami S, Ramaswami G, Alba D, Hartl C, Ou J, Parikshak N, Swarup V, Gandal M, Geschwind D. 2 Regional Variation In Transcriptional Dysregulation And Patterning In Postmortem Cerebral Cortex In Asd European Neuropsychopharmacology. 29. DOI: 10.1016/J.Euroneuro.2019.07.143  0.767
2019 Wang D, Gerstein M, Weng Z, Peters M, Liu C, White K, Geschwind D. UNDERSTANDING SINGLE CELL FUNCTIONAL GENOMICS FOR NEUROPSYCHIATRIC DISORDERS European Neuropsychopharmacology. 29: S46. DOI: 10.1016/J.Euroneuro.2019.07.093  0.367
2019 Ruzzo E, Pérez-Cano L, Jung J, Wang L, Kashef-Haghighi D, Hartl C, Lowe J, Prober D, Wall D, Geschwind D. Inherited And De Novo Genetic Risk For Autism Impacts Shared Biological Networks European Neuropsychopharmacology. 29. DOI: 10.1016/J.Euroneuro.2019.07.072  0.348
2019 Geschwind D, Buxbaum J. Advances In Autism Genetics European Neuropsychopharmacology. 29. DOI: 10.1016/J.Euroneuro.2019.07.071  0.346
2019 Gandal M, Zhang P, Walker R, Won H, Hadjimichael E, van Bakel H, Haney J, Jaffe A, White K, Peters M, Gerstein M, Liu C, Iakoucheva L, Pinto D, Geschwind D. SA75LARGE-SCALE TRANSCRIPTOME-WIDE CHARACTERIZATION OF ASD, SCHIZOPHRENIA, AND BIPOLAR DISORDER European Neuropsychopharmacology. 29: S1228. DOI: 10.1016/J.Euroneuro.2018.08.297  0.645
2019 Wong CCY, Smith RG, Hannon E, Assary E, Parikshak N, Prabhakar S, Geschwind D, Mill J. Convergent Methylomic Signatures Between Autism Associated With Duplications Of Chromosome 15Q And Idiopathic Autism European Neuropsychopharmacology. 29. DOI: 10.1016/J.Euroneuro.2017.08.359  0.727
2019 Francoeur N, Gandal M, Xu X, Sarpong K, Johnson J, Sklar P, van Bakel H, Geschwind D, Pinto D. ASSESSING THE ROLE OF LONG NONCODING RNAS (LNCRNAS) IN AUTISM SPECTRUM DISORDERS European Neuropsychopharmacology. 29: S960. DOI: 10.1016/j.euroneuro.2017.08.318  0.656
2019 Gandal M, Pinto D, Iakoucheva L, Liu C, Geschwind D. 238. Transcriptome-Wide Isoform-Level Dysregulation in Schizophrenia, Autism, and Bipolar Disorder Biological Psychiatry. 85: S98-S99. DOI: 10.1016/j.biopsych.2019.03.252  0.647
2018 Fan CC, McGrath JJ, Appadurai V, Buil A, Gandal MJ, Schork AJ, Mortensen PB, Agerbo E, Geschwind SA, Geschwind D, Werge T, Thompson WK, Pedersen CB. Spatial fine-mapping for gene-by-environment effects identifies risk hot spots for schizophrenia. Nature Communications. 9: 5296. PMID 30546018 DOI: 10.1038/s41467-018-07708-7  0.643
2018 Wang D, Liu S, Warrell J, Won H, Shi X, Navarro FCP, Clarke D, Gu M, Emani P, Yang YT, Xu M, Gandal MJ, Lou S, Zhang J, Park JJ, ... ... Geschwind DH, et al. Comprehensive functional genomic resource and integrative model for the human brain. Science (New York, N.Y.). 362. PMID 30545857 DOI: 10.1126/Science.Aat8464  0.698
2018 Gandal MJ, Zhang P, Hadjimichael E, Walker RL, Chen C, Liu S, Won H, van Bakel H, Varghese M, Wang Y, Shieh AW, Haney J, Parhami S, Belmont J, Kim M, ... ... Geschwind DH, et al. Transcriptome-wide isoform-level dysregulation in ASD, schizophrenia, and bipolar disorder. Science (New York, N.Y.). 362. PMID 30545856 DOI: 10.1126/Science.Aat8127  0.701
2018 Li M, Santpere G, Imamura Kawasawa Y, Evgrafov OV, Gulden FO, Pochareddy S, Sunkin SM, Li Z, Shin Y, Zhu Y, Sousa AMM, Werling DM, Kitchen RR, Kang HJ, Pletikos M, ... ... Geschwind DH, et al. Integrative functional genomic analysis of human brain development and neuropsychiatric risks. Science (New York, N.Y.). 362. PMID 30545854 DOI: 10.1126/Science.Aat7615  0.831
2018 Demontis D, Walters RK, Martin J, Mattheisen M, Als TD, Agerbo E, Baldursson G, Belliveau R, Bybjerg-Grauholm J, Bækvad-Hansen M, Cerrato F, Chambert K, Churchhouse C, Dumont A, Eriksson N, ... ... Geschwind D, et al. Discovery of the first genome-wide significant risk loci for attention deficit/hyperactivity disorder. Nature Genetics. PMID 30478444 DOI: 10.1038/S41588-018-0269-7  0.652
2018 Kimura R, Swarup V, Tomiwa K, Gandal MJ, Parikshak NN, Funabiki Y, Nakata M, Awaya T, Kato T, Iida K, Okazaki S, Matsushima K, Kato T, Murai T, Heike T, ... Geschwind DH, et al. Integrative network analysis reveals biological pathways associated with Williams syndrome. Journal of Child Psychology and Psychiatry, and Allied Disciplines. PMID 30362171 DOI: 10.1111/Jcpp.12999  0.771
2018 Parras A, Anta H, Santos-Galindo M, Swarup V, Elorza A, Nieto-González JL, Picó S, Hernández IH, Díaz-Hernández JI, Belloc E, Rodolosse A, Parikshak NN, Peñagarikano O, Fernández-Chacón R, Irimia M, ... ... Geschwind DH, et al. Autism-like phenotype and risk gene mRNA deadenylation by CPEB4 mis-splicing. Nature. PMID 30111840 DOI: 10.1038/S41586-018-0423-5  0.723
2018 Chen JA, Chen Z, Won H, Huang AY, Lowe JK, Wojta K, Yokoyama JS, Bensimon G, Leigh PN, Payan C, Shatunov A, Jones AR, Lewis CM, Deloukas P, Amouyel P, ... ... Geschwind DH, et al. Joint genome-wide association study of progressive supranuclear palsy identifies novel susceptibility loci and genetic correlation to neurodegenerative diseases. Molecular Neurodegeneration. 13: 41. PMID 30089514 DOI: 10.1186/S13024-018-0270-8  0.549
2018 Parikshak NN, Swarup V, Belgard TG, Irimia M, Ramaswami G, Gandal MJ, Hartl C, Leppa V, de la Torre Ubieta L, Huang J, Lowe JK, Blencowe BJ, Horvath S, Geschwind DH. Author Correction: Genome-wide changes in lncRNA, splicing, and regional gene expression patterns in autism. Nature. PMID 29995847 DOI: 10.1038/S41586-018-0295-8  0.791
2018 Raznahan A, Parikshak NN, Chandran V, Blumenthal JD, Clasen LS, Alexander-Bloch AF, Zinn AR, Wangsa D, Wise J, Murphy DGM, Bolton PF, Ried T, Ross J, Giedd JN, Geschwind DH. Sex-chromosome dosage effects on gene expression in humans. Proceedings of the National Academy of Sciences of the United States of America. PMID 29946024 DOI: 10.1073/Pnas.1802889115  0.688
2018 Anttila V, Bulik-Sullivan B, Finucane HK, Walters RK, Bras J, Duncan L, Escott-Price V, Falcone GJ, Gormley P, Malik R, Patsopoulos NA, Ripke S, Wei Z, Yu D, ... ... Geschwind DH, et al. Analysis of shared heritability in common disorders of the brain. Science (New York, N.Y.). 360. PMID 29930110 DOI: 10.1126/Science.Aap8757  0.325
2018 Schwede M, Nagpal S, Gandal MJ, Parikshak NN, Mirnics K, Geschwind DH, Morrow EM. Strong correlation of downregulated genes related to synaptic transmission and mitochondria in post-mortem autism cerebral cortex. Journal of Neurodevelopmental Disorders. 10: 18. PMID 29859039 DOI: 10.1186/S11689-018-9237-X  0.801
2018 Gusev A, Mancuso N, Won H, Kousi M, Finucane HK, Reshef Y, Song L, Safi A, McCarroll S, Neale BM, Ophoff RA, O'Donovan MC, Crawford GE, Geschwind DH, et al. Transcriptome-wide association study of schizophrenia and chromatin activity yields mechanistic disease insights. Nature Genetics. 50: 538-548. PMID 29632383 DOI: 10.1038/S41588-018-0092-1  0.333
2018 Sanders SJ, Neale BM, Huang H, Werling DM, An JY, Dong S, Abecasis G, Arguello PA, Blangero J, Boehnke M, Daly MJ, Eggan K, Geschwind DH, Glahn DC, Goldstein DB, et al. Publisher Correction: Whole genome sequencing in psychiatric disorders: the WGSPD consortium. Nature Neuroscience. PMID 29549319 DOI: 10.1038/S41593-018-0102-8  0.775
2018 Pardiñas AF, Holmans P, Pocklington AJ, Escott-Price V, Ripke S, Carrera N, Legge SE, Bishop S, Cameron D, Hamshere ML, Han J, Hubbard L, Lynham A, Mantripragada K, Rees E, ... ... Geschwind DH, et al. Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection. Nature Genetics. PMID 29483656 DOI: 10.1038/S41588-018-0059-2  0.302
2018 Gandal MJ, Haney JR, Parikshak NN, Leppa V, Ramaswami G, Hartl C, Schork AJ, Appadurai V, Buil A, Werge TM, Liu C, White KP, ... ... Geschwind DH, et al. Shared molecular neuropathology across major psychiatric disorders parallels polygenic overlap. Science (New York, N.Y.). 359: 693-697. PMID 29439242 DOI: 10.1126/Science.Aad6469  0.804
2018 Ramaswami G, Geschwind DH. Genetics of autism spectrum disorder. Handbook of Clinical Neurology. 147: 321-329. PMID 29325621 DOI: 10.1016/B978-0-444-63233-3.00021-X  0.375
2018 de la Torre-Ubieta L, Stein JL, Won H, Opland CK, Liang D, Lu D, Geschwind DH. The Dynamic Landscape of Open Chromatin during Human Cortical Neurogenesis. Cell. PMID 29307494 DOI: 10.1016/J.Cell.2017.12.014  0.544
2018 Geschwind D. 96. Genetic and Functional Genomic Investigation of Neuropsychiatric Disorders Biological Psychiatry. 83. DOI: 10.1016/J.Biopsych.2018.02.114  0.396
2017 Sanders SJ, Neale BM, Huang H, Werling DM, An JY, Dong S, Abecasis G, Arguello PA, Blangero J, Boehnke M, Daly MJ, Eggan K, Geschwind DH, Glahn DC, Goldstein DB, et al. Whole genome sequencing in psychiatric disorders: the WGSPD consortium. Nature Neuroscience. 20: 1661-1668. PMID 29184211 DOI: 10.1038/S41593-017-0017-9  0.815
2017 Tu S, Akhtar MW, Escorihuela RM, Amador-Arjona A, Swarup V, Parker J, Zaremba JD, Holland T, Bansal N, Holohan DR, Lopez K, Ryan SD, Chan SF, Yan L, Zhang X, ... ... Geschwind DH, et al. NitroSynapsin therapy for a mouse MEF2C haploinsufficiency model of human autism. Nature Communications. 8: 1488. PMID 29133852 DOI: 10.1038/S41467-017-01563-8  0.322
2017 Ecker JR, Geschwind DH, Kriegstein AR, Ngai J, Osten P, Polioudakis D, Regev A, Sestan N, Wickersham IR, Zeng H. The BRAIN Initiative Cell Census Consortium: Lessons Learned toward Generating a Comprehensive Brain Cell Atlas. Neuron. 96: 542-557. PMID 29096072 DOI: 10.1016/J.Neuron.2017.10.007  0.504
2017 Singh T, Walters JTR, Johnstone M, Curtis D, Suvisaari J, Torniainen M, Rees E, Iyegbe C, Blackwood D, McIntosh AM, Kirov G, Geschwind D, Murray RM, Di Forti M, Bramon E, et al. The contribution of rare variants to risk of schizophrenia in individuals with and without intellectual disability. Nature Genetics. PMID 28650482 DOI: 10.1038/Ng.3903  0.661
2017 Lopez A, Lee SE, Wojta K, Ramos EM, Klein E, Chen J, Boxer AL, Gorno-Tempini ML, Geschwind DH, Schlotawa L, Ogryzko NV, Bigio EH, Rogalski E, Weintraub S, Mesulam MM, et al. A152T tau allele causes neurodegeneration that can be ameliorated in a zebrafish model by autophagy induction. Brain : a Journal of Neurology. PMID 28334843 DOI: 10.1093/Brain/Awx005  0.544
2017 Ercan E, Han JM, Di Nardo A, Winden K, Han MJ, Hoyo L, Saffari A, Leask A, Geschwind DH, Sahin M. Neuronal CTGF/CCN2 negatively regulates myelination in a mouse model of tuberous sclerosis complex. The Journal of Experimental Medicine. PMID 28183733 DOI: 10.1084/Jem.20160446  0.751
2017 Bagot R, Cates H, Purushothaman I, Lorsch Z, Geschwind D, Dong Y, Shen L, Zhang B, Nestler E. 374. Circuit-Wide Transcriptional Profiling Reveals Region Specific Gene Co-Expression Networks Regulating Depression Susceptibility Biological Psychiatry. 81: S153. DOI: 10.1016/J.Biopsych.2017.02.391  0.347
2016 Parikshak NN, Swarup V, Belgard TG, Irimia M, Ramaswami G, Gandal MJ, Hartl C, Leppa V, Ubieta LT, Huang J, Lowe JK, Blencowe BJ, Horvath S, Geschwind DH. Genome-wide changes in lncRNA, splicing, and regional gene expression patterns in autism. Nature. PMID 27919067 DOI: 10.1038/Nature20612  0.846
2016 Sun W, Poschmann J, Cruz-Herrera Del Rosario R, Parikshak NN, Hajan HS, Kumar V, Ramasamy R, Belgard TG, Elanggovan B, Wong CC, Mill J, Geschwind DH, Prabhakar S. Histone Acetylome-wide Association Study of Autism Spectrum Disorder. Cell. 167: 1385-1397.e11. PMID 27863250 DOI: 10.1016/J.Cell.2016.10.031  0.819
2016 Gandal MJ, Leppa V, Won H, Parikshak NN, Geschwind DH. The road to precision psychiatry: translating genetics into disease mechanisms. Nature Neuroscience. 19: 1397-1407. PMID 27786179 DOI: 10.1038/Nn.4409  0.789
2016 Won H, de la Torre-Ubieta L, Stein JL, Parikshak NN, Huang J, Opland CK, Gandal MJ, Sutton GJ, Hormozdiari F, Lu D, Lee C, Eskin E, Voineagu I, Ernst J, Geschwind DH. Chromosome conformation elucidates regulatory relationships in developing human brain. Nature. PMID 27760116 DOI: 10.1038/Nature19847  0.828
2016 Wu YE, Parikshak NN, Belgard TG, Geschwind DH. Genome-wide, integrative analysis implicates microRNA dysregulation in autism spectrum disorder. Nature Neuroscience. PMID 27571009 DOI: 10.1038/Nn.4373  0.797
2016 Leppa VM, Kravitz SN, Martin CL, Andrieux J, Le Caignec C, Martin-Coignard D, DyBuncio C, Sanders SJ, Lowe JK, Cantor RM, Geschwind DH. Rare Inherited and De Novo CNVs Reveal Complex Contributions to ASD Risk in Multiplex Families. American Journal of Human Genetics. PMID 27569545 DOI: 10.1016/J.Ajhg.2016.06.036  0.587
2016 Marchetto MC, Belinson H, Tian Y, Freitas BC, Fu C, Vadodaria KC, Beltrao-Braga PC, Trujillo CA, Mendes AP, Padmanabhan K, Nunez Y, Ou J, Ghosh H, Wright R, Brennand KJ, ... ... Geschwind DH, et al. Altered proliferation and networks in neural cells derived from idiopathic autistic individuals. Molecular Psychiatry. PMID 27378147 DOI: 10.1038/Mp.2016.95  0.319
2016 Bagot RC, Cates HM, Purushothaman I, Lorsch ZS, Walker DM, Wang J, Huang X, Schlüter OM, Maze I, Peña CJ, Heller EA, Issler O, Wang M, Song WM, Stein JL, ... ... Geschwind D, et al. Circuit-wide Transcriptional Profiling Reveals Brain Region-Specific Gene Networks Regulating Depression Susceptibility. Neuron. PMID 27181059 DOI: 10.1016/J.Neuron.2016.04.015  0.584
2016 de la Torre-Ubieta L, Won H, Stein JL, Geschwind DH. Advancing the understanding of autism disease mechanisms through genetics. Nature Medicine. 22: 345-361. PMID 27050589 DOI: 10.1038/Nm.4071  0.534
2016 Gandal MJ, Geschwind DH. The Genetics-Driven Revival in Neuropsychiatric Drug Development. Biological Psychiatry. 79: 628-30. PMID 26997117 DOI: 10.1016/j.biopsych.2016.02.024  0.661
2016 Singh T, Kurki MI, Curtis D, Purcell SM, Crooks L, McRae J, Suvisaari J, Chheda H, Blackwood D, Breen G, Pietiläinen O, Gerety SS, Ayub M, Blyth M, Cole T, ... ... Geschwind D, et al. Rare loss-of-function variants in SETD1A are associated with schizophrenia and developmental disorders. Nature Neuroscience. PMID 26974950 DOI: 10.1038/Nn.4267  0.367
2016 Werling DM, Parikshak NN, Geschwind DH. Gene expression in human brain implicates sexually dimorphic pathways in autism spectrum disorders. Nature Communications. 7: 10717. PMID 26892004 DOI: 10.1038/Ncomms10717  0.825
2015 Lee JA, Damianov A, Lin CH, Fontes M, Parikshak NN, Anderson ES, Geschwind DH, Black DL, Martin KC. Cytoplasmic Rbfox1 Regulates the Expression of Synaptic and Autism-Related Genes. Neuron. PMID 26687839 DOI: 10.1016/J.Neuron.2015.11.025  0.686
2015 Berg JM, Lee C, Chen L, Galvan L, Cepeda C, Chen JY, Peñagarikano O, Stein JL, Li A, Oguro-Ando A, Miller JA, Vashisht AA, Starks ME, Kite EP, Tam E, ... ... Geschwind DH, et al. JAKMIP1, a Novel Regulator of Neuronal Translation, Modulates Synaptic Function and Autistic-like Behaviors in Mouse. Neuron. PMID 26627310 DOI: 10.1016/J.Neuron.2015.10.031  0.671
2015 Akbarian S, Liu C, Knowles JA, Vaccarino FM, Farnham PJ, Crawford GE, Jaffe AE, Pinto D, Dracheva S, Geschwind DH, Mill J, Nairn AC, Abyzov A, Pochareddy S, Prabhakar S, et al. The PsychENCODE project. Nature Neuroscience. 18: 1707-1712. PMID 26605881 DOI: 10.1038/Nn.4156  0.833
2015 Wang GZ, Belgard TG, Mao D, Chen L, Berto S, Preuss TM, Lu H, Geschwind DH, Konopka G. Correspondence between Resting-State Activity and Brain Gene Expression. Neuron. 88: 659-666. PMID 26590343 DOI: 10.1016/J.Neuron.2015.10.022  0.802
2015 Sanders SJ, He X, Willsey AJ, Ercan-Sencicek AG, Samocha KE, Cicek AE, Murtha MT, Bal VH, Bishop SL, Dong S, Goldberg AP, Jinlu C, Keaney JF, Klei L, Mandell JD, ... ... Geschwind DH, et al. Insights into Autism Spectrum Disorder Genomic Architecture and Biology from 71 Risk Loci. Neuron. 87: 1215-1233. PMID 26402605 DOI: 10.1016/J.Neuron.2015.09.016  0.818
2015 Jalbrzikowski M, Lazaro MT, Gao F, Huang A, Chow C, Geschwind DH, Coppola G, Bearden CE. Transcriptome Profiling of Peripheral Blood in 22q11.2 Deletion Syndrome Reveals Functional Pathways Related to Psychosis and Autism Spectrum Disorder. Plos One. 10: e0132542. PMID 26201030 DOI: 10.1371/Journal.Pone.0132542  0.405
2015 Kloth AD, Badura A, Li A, Cherskov A, Connolly SG, Giovannucci A, Bangash MA, Grasselli G, Peñagarikano O, Piochon C, Tsai PT, Geschwind DH, Hansel C, Sahin M, Takumi T, et al. Cerebellar associative sensory learning defects in five mouse autism models. Elife. 4. PMID 26158416 DOI: 10.7554/Elife.06085  0.348
2015 Parikshak NN, Gandal MJ, Geschwind DH. Systems biology and gene networks in neurodevelopmental and neurodegenerative disorders. Nature Reviews. Genetics. 16: 441-58. PMID 26149713 DOI: 10.1038/Nrg3934  0.799
2015 Nicolas G, Charbonnier C, de Lemos RR, Richard AC, Guillin O, Wallon D, Legati A, Geschwind D, Coppola G, Frebourg T, Campion D, de Oliveira JR, Hannequin D. Brain calcification process and phenotypes according to age and sex: Lessons from SLC20A2, PDGFB, and PDGFRB mutation carriers. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. PMID 26129893 DOI: 10.1002/Ajmg.B.32336  0.364
2015 Werling DM, Geschwind DH. Recurrence rates provide evidence for sex-differential, familial genetic liability for autism spectrum disorders in multiplex families and twins. Molecular Autism. 6: 27. PMID 25973164 DOI: 10.1186/S13229-015-0004-5  0.711
2015 Bakken TE, Miller JA, Luo R, Bernard A, Bennett JL, Lee CK, Bertagnolli D, Parikshak NN, Smith KA, Sunkin SM, Amaral DG, Geschwind DH, Lein ES. Spatiotemporal dynamics of the postnatal developing primate brain transcriptome. Human Molecular Genetics. 24: 4327-39. PMID 25954031 DOI: 10.1093/Hmg/Ddv166  0.806
2015 Raposo M, Bettencourt C, Maciel P, Gao F, Ramos A, Kazachkova N, Vasconcelos J, Kay T, Rodrigues AJ, Bettencourt B, Bruges-Armas J, Geschwind D, Coppola G, Lima M. Novel candidate blood-based transcriptional biomarkers of machado-joseph disease. Movement Disorders : Official Journal of the Movement Disorder Society. 30: 968-75. PMID 25914309 DOI: 10.1002/mds.26238  0.387
2015 Geschwind DH, State MW. Gene hunting in autism spectrum disorder: on the path to precision medicine. The Lancet. Neurology. PMID 25891009 DOI: 10.1016/S1474-4422(15)00044-7  0.628
2015 Winden KD, Bragin A, Engel J, Geschwind DH. Molecular alterations in areas generating fast ripples in an animal model of temporal lobe epilepsy. Neurobiology of Disease. 78: 35-44. PMID 25818007 DOI: 10.1016/J.Nbd.2015.02.011  0.754
2015 Martinez RA, Stein JL, Krostag AR, Nelson AM, Marken JS, Menon V, May RC, Yao Z, Kaykas A, Geschwind DH, Grimley JS. Genome engineering of isogenic human ES cells to model autism disorders. Nucleic Acids Research. 43: e65. PMID 25765640 DOI: 10.1093/Nar/Gkv164  0.563
2015 Lowe JK, Werling DM, Constantino JN, Cantor RM, Geschwind DH. Social responsiveness, an autism endophenotype: genomewide significant linkage to two regions on chromosome 8. The American Journal of Psychiatry. 172: 266-75. PMID 25727539 DOI: 10.1176/Appi.Ajp.2014.14050576  0.738
2015 Chen JA, Wang Q, Davis-Turak J, Li Y, Karydas AM, Hsu SC, Sears RL, Chatzopoulou D, Huang AY, Wojta KJ, Klein E, Lee J, Beekly DL, Boxer A, Faber KM, ... ... Geschwind DH, et al. A multiancestral genome-wide exome array study of Alzheimer disease, frontotemporal dementia, and progressive supranuclear palsy. Jama Neurology. 72: 414-22. PMID 25706306 DOI: 10.1001/Jamaneurol.2014.4040  0.495
2015 Chen JA, Peñagarikano O, Belgard TG, Swarup V, Geschwind DH. The emerging picture of autism spectrum disorder: genetics and pathology. Annual Review of Pathology. 10: 111-44. PMID 25621659 DOI: 10.1146/Annurev-Pathol-012414-040405  0.809
2015 Chaste P, Klei L, Sanders SJ, Hus V, Murtha MT, Lowe JK, Willsey AJ, Moreno-De-Luca D, Yu TW, Fombonne E, Geschwind D, Grice DE, Ledbetter DH, Mane SM, Martin DM, et al. A genome-wide association study of autism using the Simons Simplex Collection: Does reducing phenotypic heterogeneity in autism increase genetic homogeneity? Biological Psychiatry. 77: 775-84. PMID 25534755 DOI: 10.1016/J.Biopsych.2014.09.017  0.747
2015 State MW, Geschwind DH. Leveraging genetics and genomics to define the causes of mental illness. Biological Psychiatry. 77: 3-5. PMID 25483342 DOI: 10.1016/J.Biopsych.2014.11.003  0.527
2015 Werling DM, Geschwind DH. Recurrence rates provide evidence for sex-differential, familial genetic liability for autism spectrum disorders in multiplex families and twins Molecular Autism. DOI: 10.1186/s13229-015-0004-5  0.728
2014 Irimia M, Weatheritt RJ, Ellis JD, Parikshak NN, Gonatopoulos-Pournatzis T, Babor M, Quesnel-Vallières M, Tapial J, Raj B, O'Hanlon D, Barrios-Rodiles M, Sternberg MJ, Cordes SP, Roth FP, Wrana JL, ... Geschwind DH, et al. A highly conserved program of neuronal microexons is misregulated in autistic brains. Cell. 159: 1511-23. PMID 25525873 DOI: 10.1016/J.Cell.2014.11.035  0.675
2014 Tian Y, Voineagu I, Pa?ca SP, Won H, Chandran V, Horvath S, Dolmetsch RE, Geschwind DH. Alteration in basal and depolarization induced transcriptional network in iPSC derived neurons from Timothy syndrome. Genome Medicine. 6: 75. PMID 25360157 DOI: 10.1186/S13073-014-0075-5  0.349
2014 Oguro-Ando A, Rosensweig C, Herman E, Nishimura Y, Werling D, Bill BR, Berg JM, Gao F, Coppola G, Abrahams BS, Geschwind DH. Increased CYFIP1 dosage alters cellular and dendritic morphology and dysregulates mTOR. Molecular Psychiatry. PMID 25311365 DOI: 10.1038/Mp.2014.124  0.816
2014 Stein JL, de la Torre-Ubieta L, Tian Y, Parikshak NN, Hernández IA, Marchetto MC, Baker DK, Lu D, Hinman CR, Lowe JK, Wexler EM, Muotri AR, Gage FH, Kosik KS, Geschwind DH. A quantitative framework to evaluate modeling of cortical development by neural stem cells. Neuron. 83: 69-86. PMID 24991955 DOI: 10.1016/J.Neuron.2014.05.035  0.807
2014 Fogel BL, Clark MC, Geschwind DH. The neurogenetics of atypical parkinsonian disorders. Seminars in Neurology. 34: 217-24. PMID 24963681 DOI: 10.1055/S-0034-1381738  0.334
2014 Chaste P, Sanders SJ, Mohan KN, Klei L, Song Y, Murtha MT, Hus V, Lowe JK, Willsey AJ, Moreno-De-Luca D, Yu TW, Fombonne E, Geschwind D, Grice DE, Ledbetter DH, et al. Modest impact on risk for autism spectrum disorder of rare copy number variants at 15q11.2, specifically breakpoints 1 to 2. Autism Research : Official Journal of the International Society For Autism Research. 7: 355-62. PMID 24821083 DOI: 10.1002/Aur.1378  0.74
2014 Pinto D, Delaby E, Merico D, Barbosa M, Merikangas A, Klei L, Thiruvahindrapuram B, Xu X, Ziman R, Wang Z, Vorstman JA, Thompson A, Regan R, Pilorge M, Pellecchia G, ... ... Geschwind DH, et al. Convergence of genes and cellular pathways dysregulated in autism spectrum disorders. American Journal of Human Genetics. 94: 677-94. PMID 24768552 DOI: 10.1016/J.Ajhg.2014.03.018  0.359
2014 Fogel BL, Cho E, Wahnich A, Gao F, Becherel OJ, Wang X, Fike F, Chen L, Criscuolo C, De Michele G, Filla A, Collins A, Hahn AF, Gatti RA, Konopka G, ... ... Geschwind DH, et al. Mutation of senataxin alters disease-specific transcriptional networks in patients with ataxia with oculomotor apraxia type 2. Human Molecular Genetics. 23: 4758-69. PMID 24760770 DOI: 10.1093/Hmg/Ddu190  0.646
2014 Correia CT, Conceição IC, Oliveira B, Coelho J, Sousa I, Sequeira AF, Almeida J, Café C, Duque F, Mouga S, Roberts W, Gao K, Lowe JK, Thiruvahindrapuram B, Walker S, ... ... Geschwind DH, et al. Recurrent duplications of the annexin A1 gene (ANXA1) in autism spectrum disorders. Molecular Autism. 5: 28. PMID 24720851 DOI: 10.1186/2040-2392-5-28  0.364
2014 Miller JA, Ding SL, Sunkin SM, Smith KA, Ng L, Szafer A, Ebbert A, Riley ZL, Royall JJ, Aiona K, Arnold JM, Bennet C, Bertagnolli D, Brouner K, Butler S, ... ... Geschwind DH, et al. Transcriptional landscape of the prenatal human brain. Nature. 508: 199-206. PMID 24695229 DOI: 10.1038/Nature13185  0.536
2014 Li Y, Chen JA, Sears RL, Gao F, Klein ED, Karydas A, Geschwind MD, Rosen HJ, Boxer AL, Guo W, Pellegrini M, Horvath S, Miller BL, Geschwind DH, Coppola G. An epigenetic signature in peripheral blood associated with the haplotype on 17q21.31, a risk factor for neurodegenerative tauopathy. Plos Genetics. 10: e1004211. PMID 24603599 DOI: 10.1371/Journal.Pgen.1004211  0.534
2014 Werling DM, Lowe JK, Luo R, Cantor RM, Geschwind DH. Replication of linkage at chromosome 20p13 and identification of suggestive sex-differential risk loci for autism spectrum disorder. Molecular Autism. 5: 13. PMID 24533643 DOI: 10.1186/2040-2392-5-13  0.772
2014 Jeste SS, Geschwind DH. Disentangling the heterogeneity of autism spectrum disorder through genetic findings. Nature Reviews. Neurology. 10: 74-81. PMID 24468882 DOI: 10.1038/nrneurol.2013.278  0.324
2014 Belgard TG, Jankovic I, Lowe JK, Geschwind DH. Population structure confounds autism genetic classifier. Molecular Psychiatry. 19: 405-7. PMID 23546168 DOI: 10.1038/mp.2013.34  0.699
2014 Schwede M, Garbett K, Mirnics K, Geschwind DH, Morrow EM. Genes for endosomal NHE6 and NHE9 are misregulated in autism brains. Molecular Psychiatry. 19: 277-9. PMID 23508127 DOI: 10.1038/Mp.2013.28  0.307
2013 Parikshak NN, Luo R, Zhang A, Won H, Lowe JK, Chandran V, Horvath S, Geschwind DH. Integrative functional genomic analyses implicate specific molecular pathways and circuits in autism. Cell. 155: 1008-21. PMID 24267887 DOI: 10.1016/J.Cell.2013.10.031  0.78
2013 Geschwind DH, Rakic P. Cortical evolution: judge the brain by its cover. Neuron. 80: 633-47. PMID 24183016 DOI: 10.1016/j.neuron.2013.10.045  0.312
2013 Lee SH, Ripke S, Neale BM, Faraone SV, Purcell SM, Perlis RH, Mowry BJ, Thapar A, Goddard ME, Witte JS, Absher D, Agartz I, Akil H, Amin F, ... ... Geschwind DH, et al. Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs. Nature Genetics. 45: 984-94. PMID 23933821 DOI: 10.1038/Ng.2711  0.75
2013 Gamsiz ED, Viscidi EW, Frederick AM, Nagpal S, Sanders SJ, Murtha MT, Schmidt M, Triche EW, Geschwind DH, State MW, Istrail S, Cook EH, Devlin B, Morrow EM. Intellectual disability is associated with increased runs of homozygosity in simplex autism. American Journal of Human Genetics. 93: 103-9. PMID 23830515 DOI: 10.1016/J.Ajhg.2013.06.004  0.745
2013 Chaste P, Klei L, Sanders SJ, Murtha MT, Hus V, Lowe JK, Willsey AJ, Moreno-De-Luca D, Yu TW, Fombonne E, Geschwind D, Grice DE, Ledbetter DH, Lord C, Mane SM, et al. Adjusting head circumference for covariates in autism: clinical correlates of a highly heritable continuous trait. Biological Psychiatry. 74: 576-84. PMID 23746936 DOI: 10.1016/J.Biopsych.2013.04.018  0.734
2013 Miller JA, Woltjer RL, Goodenbour JM, Horvath S, Geschwind DH. Genes and pathways underlying regional and cell type changes in Alzheimer's disease. Genome Medicine. 5: 48. PMID 23705665 DOI: 10.1186/Gm452  0.533
2013 Juknat A, Pietr M, Kozela E, Rimmerman N, Levy R, Gao F, Coppola G, Geschwind D, Vogel Z. Microarray and pathway analysis reveal distinct mechanisms underlying cannabinoid-mediated modulation of LPS-induced activation of BV-2 microglial cells. Plos One. 8: e61462. PMID 23637839 DOI: 10.1371/Journal.Pone.0061462  0.345
2013 Yamada T, Yang Y, Huang J, Coppola G, Geschwind DH, Bonni A. Sumoylated MEF2A coordinately eliminates orphan presynaptic sites and promotes maturation of presynaptic boutons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 4726-40. PMID 23486945 DOI: 10.1523/Jneurosci.4191-12.2013  0.577
2013 Werling DM, Geschwind DH. Understanding sex bias in autism spectrum disorder. Proceedings of the National Academy of Sciences of the United States of America. 110: 4868-9. PMID 23476067 DOI: 10.1073/Pnas.1301602110  0.714
2013 Dougherty JD, Maloney SE, Wozniak DF, Rieger MA, Sonnenblick L, Coppola G, Mahieu NG, Zhang J, Cai J, Patti GJ, Abrahams BS, Geschwind DH, Heintz N. The disruption of Celf6, a gene identified by translational profiling of serotonergic neurons, results in autism-related behaviors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 2732-53. PMID 23407934 DOI: 10.1523/Jneurosci.4762-12.2013  0.83
2013 Werling DM, Geschwind DH. Sex differences in autism spectrum disorders. Current Opinion in Neurology. 26: 146-53. PMID 23406909 DOI: 10.1097/Wco.0B013E32835Ee548  0.731
2013 Stein JL, Parikshak NN, Geschwind DH. Rare inherited variation in autism: beginning to see the forest and a few trees. Neuron. 77: 209-11. PMID 23352155 DOI: 10.1016/J.Neuron.2013.01.010  0.739
2013 Belgard TG, Geschwind DH. Retooling spare parts: gene duplication and cognition. Nature Neuroscience. 16: 6-8. PMID 23257927 DOI: 10.1038/Nn.3292  0.708
2013 Moreno-De-Luca D, Sanders SJ, Willsey AJ, Mulle JG, Lowe JK, Geschwind DH, State MW, Martin CL, Ledbetter DH. Using large clinical data sets to infer pathogenicity for rare copy number variants in autism cohorts. Molecular Psychiatry. 18: 1090-5. PMID 23044707 DOI: 10.1038/Mp.2012.138  0.722
2013 Constantino JN, Todorov A, Hilton C, Law P, Zhang Y, Molloy E, Fitzgerald R, Geschwind D. Autism recurrence in half siblings: strong support for genetic mechanisms of transmission in ASD. Molecular Psychiatry. 18: 137-8. PMID 22371046 DOI: 10.1038/Mp.2012.9  0.358
2013 Lu AT, Yoon J, Geschwind DH, Cantor RM. QTL replication and targeted association highlight the nerve growth factor gene for nonverbal communication deficits in autism spectrum disorders. Molecular Psychiatry. 18: 226-35. PMID 22105621 DOI: 10.1038/mp.2011.155  0.312
2013 Parikshak NN, Geschwind DH. Neuroscience and the Genomic Revolution: An Overview Genomic and Personalized Medicine. 2: 1018-1027. DOI: 10.1016/B978-0-12-382227-7.00084-7  0.627
2012 Klei L, Sanders SJ, Murtha MT, Hus V, Lowe JK, Willsey AJ, Moreno-De-Luca D, Yu TW, Fombonne E, Geschwind D, Grice DE, Ledbetter DH, Lord C, Mane SM, Martin CL, et al. Common genetic variants, acting additively, are a major source of risk for autism. Molecular Autism. 3: 9. PMID 23067556 DOI: 10.1186/2040-2392-3-9  0.741
2012 Hawrylycz MJ, Lein ES, Guillozet-Bongaarts AL, Shen EH, Ng L, Miller JA, van de Lagemaat LN, Smith KA, Ebbert A, Riley ZL, Abajian C, Beckmann CF, Bernard A, Bertagnolli D, Boe AF, ... ... Geschwind DH, et al. An anatomically comprehensive atlas of the adult human brain transcriptome. Nature. 489: 391-9. PMID 22996553 DOI: 10.1038/Nature11405  0.582
2012 Rudie JD, Hernandez LM, Brown JA, Beck-Pancer D, Colich NL, Gorrindo P, Thompson PM, Geschwind DH, Bookheimer SY, Levitt P, Dapretto M. Autism-associated promoter variant in MET impacts functional and structural brain networks. Neuron. 75: 904-15. PMID 22958829 DOI: 10.1016/J.Neuron.2012.07.010  0.462
2012 Zeng J, Konopka G, Hunt BG, Preuss TM, Geschwind D, Yi SV. Divergent whole-genome methylation maps of human and chimpanzee brains reveal epigenetic basis of human regulatory evolution. American Journal of Human Genetics. 91: 455-65. PMID 22922032 DOI: 10.1016/J.Ajhg.2012.07.024  0.647
2012 Konopka G, Friedrich T, Davis-Turak J, Winden K, Oldham MC, Gao F, Chen L, Wang GZ, Luo R, Preuss TM, Geschwind DH. Human-specific transcriptional networks in the brain. Neuron. 75: 601-17. PMID 22920253 DOI: 10.1016/J.Neuron.2012.05.034  0.825
2012 Berg JM, Geschwind DH. Autism genetics: searching for specificity and convergence. Genome Biology. 13: 247. PMID 22849751 DOI: 10.1186/gb4034  0.358
2012 Fogel BL, Wexler E, Wahnich A, Friedrich T, Vijayendran C, Gao F, Parikshak N, Konopka G, Geschwind DH. RBFOX1 regulates both splicing and transcriptional networks in human neuronal development. Human Molecular Genetics. 21: 4171-86. PMID 22730494 DOI: 10.1093/Hmg/Dds240  0.818
2012 Luo R, Sanders SJ, Tian Y, Voineagu I, Huang N, Chu SH, Klei L, Cai C, Ou J, Lowe JK, Hurles ME, Devlin B, State MW, Geschwind DH. Genome-wide transcriptome profiling reveals the functional impact of rare de novo and recurrent CNVs in autism spectrum disorders. American Journal of Human Genetics. 91: 38-55. PMID 22726847 DOI: 10.1016/J.Ajhg.2012.05.011  0.792
2012 Geschwind DH, Konopka G. Neuroscience: Genes and human brain evolution. Nature. 486: 481-2. PMID 22722844 DOI: 10.1038/nature11380  0.605
2012 Celestino-Soper PB, Violante S, Crawford EL, Luo R, Lionel AC, Delaby E, Cai G, Sadikovic B, Lee K, Lo C, Gao K, Person RE, Moss TJ, German JR, Huang N, ... ... Geschwind DH, et al. A common X-linked inborn error of carnitine biosynthesis may be a risk factor for nondysmorphic autism. Proceedings of the National Academy of Sciences of the United States of America. 109: 7974-81. PMID 22566635 DOI: 10.1073/Pnas.1120210109  0.649
2012 Sanders SJ, Murtha MT, Gupta AR, Murdoch JD, Raubeson MJ, Willsey AJ, Ercan-Sencicek AG, DiLullo NM, Parikshak NN, Stein JL, Walker MF, Ober GT, Teran NA, Song Y, El-Fishawy P, ... ... Geschwind DH, et al. De novo mutations revealed by whole-exome sequencing are strongly associated with autism. Nature. 485: 237-41. PMID 22495306 DOI: 10.1038/Nature10945  0.813
2012 Lunnon K, Ibrahim Z, Proitsi P, Lourdusamy A, Newhouse S, Sattlecker M, Furney S, Saleem M, Soininen H, K?oszewska I, Mecocci P, Tsolaki M, Vellas B, Coppola G, Geschwind D, et al. Mitochondrial dysfunction and immune activation are detectable in early Alzheimer's disease blood. Journal of Alzheimer's Disease : Jad. 30: 685-710. PMID 22466004 DOI: 10.3233/Jad-2012-111592  0.335
2012 Bernard A, Lubbers LS, Tanis KQ, Luo R, Podtelezhnikov AA, Finney EM, McWhorter MM, Serikawa K, Lemon T, Morgan R, Copeland C, Smith K, Cullen V, Davis-Turak J, Lee CK, ... ... Geschwind DH, et al. Transcriptional architecture of the primate neocortex. Neuron. 73: 1083-99. PMID 22445337 DOI: 10.1016/J.Neuron.2012.03.002  0.451
2012 Peñagarikano O, Geschwind DH. What does CNTNAP2 reveal about autism spectrum disorder? Trends in Molecular Medicine. 18: 156-63. PMID 22365836 DOI: 10.1016/j.molmed.2012.01.003  0.361
2012 Casey JP, Magalhaes T, Conroy JM, Regan R, Shah N, Anney R, Shields DC, Abrahams BS, Almeida J, Bacchelli E, Bailey AJ, Baird G, Battaglia A, Berney T, Bolshakova N, ... ... Geschwind DH, et al. A novel approach of homozygous haplotype sharing identifies candidate genes in autism spectrum disorder. Human Genetics. 131: 565-79. PMID 21996756 DOI: 10.1007/S00439-011-1094-6  0.758
2012 Voineagu I, Huang L, Winden K, Lazaro M, Haan E, Nelson J, McGaughran J, Nguyen LS, Friend K, Hackett A, Field M, Gecz J, Geschwind D. CCDC22: a novel candidate gene for syndromic X-linked intellectual disability. Molecular Psychiatry. 17: 4-7. PMID 21826058 DOI: 10.1038/Mp.2011.95  0.762
2012 Konopka G, Wexler E, Rosen E, Mukamel Z, Osborn GE, Chen L, Lu D, Gao F, Gao K, Lowe JK, Geschwind DH. Modeling the functional genomics of autism using human neurons. Molecular Psychiatry. 17: 202-14. PMID 21647150 DOI: 10.1038/mp.2011.60  0.829
2012 Juknat A, Pietr M, Kozela E, Rimmerman N, Levy R, Coppola G, Geschwind D, Vogel Z. Differential transcriptional profiles mediated by exposure to the cannabinoids cannabidiol and Δ9-tetrahydrocannabinol in BV-2 microglial cells. British Journal of Pharmacology. 165: 2512-28. PMID 21542829 DOI: 10.1111/J.1476-5381.2011.01461.X  0.381
2012 Ehninger D, Sano Y, de Vries PJ, Dies K, Franz D, Geschwind DH, Kaur M, Lee YS, Li W, Lowe JK, Nakagawa JA, Sahin M, Smith K, Whittemore V, Silva AJ. Gestational immune activation and Tsc2 haploinsufficiency cooperate to disrupt fetal survival and may perturb social behavior in adult mice. Molecular Psychiatry. 17: 62-70. PMID 21079609 DOI: 10.1038/Mp.2010.115  0.444
2012 Ehninger D, Sano Y, De Vries PJ, Dies K, Franz D, Geschwind DH, Kaur M, Lee YS, Li W, Lowe JK, Nakagawa JA, Sahin M, Smith K, Whittemore V, Silva AJ. Gestational immune activation and Tsc2 haploinsufficiency cooperate to disrupt fetal survival and may perturb social behavior in adult mice (Molecular Psychiatry (2012) 17, (62-70) DOI:10.1038/mp.2010.115) Molecular Psychiatry. 17: 469-470. DOI: 10.1038/Mp.2011.39  0.322
2011 Pa?ca SP, Portmann T, Voineagu I, Yazawa M, Shcheglovitov A, Pa?ca AM, Cord B, Palmer TD, Chikahisa S, Nishino S, Bernstein JA, Hallmayer J, Geschwind DH, Dolmetsch RE. Using iPSC-derived neurons to uncover cellular phenotypes associated with Timothy syndrome. Nature Medicine. 17: 1657-62. PMID 22120178 DOI: 10.1038/Nm.2576  0.608
2011 Wexler EM, Geschwind DH. DISC1: a schizophrenia gene with multiple personalities. Neuron. 72: 501-3. PMID 22099453 DOI: 10.1016/j.neuron.2011.10.023  0.643
2011 Wexler EM, Rosen E, Lu D, Osborn GE, Martin E, Raybould H, Geschwind DH. Genome-wide analysis of a Wnt1-regulated transcriptional network implicates neurodegenerative pathways. Science Signaling. 4: ra65. PMID 21971039 DOI: 10.1126/Scisignal.2002282  0.741
2011 Peñagarikano O, Abrahams BS, Herman EI, Winden KD, Gdalyahu A, Dong H, Sonnenblick LI, Gruver R, Almajano J, Bragin A, Golshani P, Trachtenberg JT, Peles E, Geschwind DH. Absence of CNTNAP2 leads to epilepsy, neuronal migration abnormalities, and core autism-related deficits. Cell. 147: 235-46. PMID 21962519 DOI: 10.1016/J.Cell.2011.08.040  0.82
2011 Rosen EY, Wexler EM, Versano R, Coppola G, Gao F, Winden KD, Oldham MC, Martens LH, Zhou P, Farese RV, Geschwind DH. Functional genomic analyses identify pathways dysregulated by progranulin deficiency, implicating Wnt signaling. Neuron. 71: 1030-42. PMID 21943601 DOI: 10.1016/J.Neuron.2011.07.021  0.812
2011 Geschwind DH. Genetics of autism spectrum disorders. Trends in Cognitive Sciences. 15: 409-16. PMID 21855394 DOI: 10.1016/j.tics.2011.07.003  0.363
2011 Mukamel Z, Konopka G, Wexler E, Osborn GE, Dong H, Bergman MY, Levitt P, Geschwind DH. Regulation of MET by FOXP2, genes implicated in higher cognitive dysfunction and autism risk. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 11437-42. PMID 21832174 DOI: 10.1523/JNEUROSCI.0181-11.2011  0.801
2011 Miller JA, Cai C, Langfelder P, Geschwind DH, Kurian SM, Salomon DR, Horvath S. Strategies for aggregating gene expression data: the collapseRows R function. Bmc Bioinformatics. 12: 322. PMID 21816037 DOI: 10.1186/1471-2105-12-322  0.542
2011 Vernes SC, Oliver PL, Spiteri E, Lockstone HE, Puliyadi R, Taylor JM, Ho J, Mombereau C, Brewer A, Lowy E, Nicod J, Groszer M, Baban D, Sahgal N, Cazier JB, ... ... Geschwind DH, et al. Foxp2 regulates gene networks implicated in neurite outgrowth in the developing brain. Plos Genetics. 7: e1002145. PMID 21765815 DOI: 10.1371/Journal.Pgen.1002145  0.328
2011 Winden KD, Karsten SL, Bragin A, Kudo LC, Gehman L, Ruidera J, Geschwind DH, Engel J. A systems level, functional genomics analysis of chronic epilepsy. Plos One. 6: e20763. PMID 21695113 DOI: 10.1371/Journal.Pone.0020763  0.807
2011 Sanders SJ, Ercan-Sencicek AG, Hus V, Luo R, Murtha MT, Moreno-De-Luca D, Chu SH, Moreau MP, Gupta AR, Thomson SA, Mason CE, Bilguvar K, Celestino-Soper PB, Choi M, Crawford EL, ... ... Geschwind D, et al. Multiple recurrent de novo CNVs, including duplications of the 7q11.23 Williams syndrome region, are strongly associated with autism. Neuron. 70: 863-85. PMID 21658581 DOI: 10.1016/J.Neuron.2011.05.002  0.776
2011 Voineagu I, Wang X, Johnston P, Lowe JK, Tian Y, Horvath S, Mill J, Cantor RM, Blencowe BJ, Geschwind DH. Transcriptomic analysis of autistic brain reveals convergent molecular pathology. Nature. 474: 380-4. PMID 21614001 DOI: 10.1038/Nature10110  0.448
2011 Lu PH, Thompson PM, Leow A, Lee GJ, Lee A, Yanovsky I, Parikshak N, Khoo T, Wu S, Geschwind D, Bartzokis G. Apolipoprotein E genotype is associated with temporal and hippocampal atrophy rates in healthy elderly adults: a tensor-based morphometry study. Journal of Alzheimer's Disease : Jad. 23: 433-42. PMID 21098974 DOI: 10.3233/Jad-2010-101398  0.687
2011 Jamieson C, Petrigliano F, Belanto J, Virk M, Coppola G, Tchieu J, Fu E, Magyar C, Raheem O, Kazarian M, Morris S, Cacalano N, Geschwind D, Tetradis S, Jamieson C, et al. 1451 GENOME-WIDE EXPRESSION PROFILING OF CASTRATION-RESISTANT PROSTATE CANCER XENOGRAFTS IN THE BONE-NICHE REVEALED UP-REGULATION OF THE ANTI-APOPTOSIS GENE, YWHAZ, A NETWORK MODULE HUB GENE Journal of Urology. 185. DOI: 10.1016/J.Juro.2011.02.1364  0.335
2010 Scott-Van Zeeland AA, Abrahams BS, Alvarez-Retuerto AI, Sonnenblick LI, Rudie JD, Ghahremani D, Mumford JA, Poldrack RA, Dapretto M, Geschwind DH, Bookheimer SY. Altered functional connectivity in frontal lobe circuits is associated with variation in the autism risk gene CNTNAP2. Science Translational Medicine. 2: 56ra80. PMID 21048216 DOI: 10.1126/Scitranslmed.3001344  0.743
2010 Wang S, Chandler-Militello D, Lu G, Roy NS, Zielke A, Auvergne R, Stanwood N, Geschwind D, Coppola G, Nicolis SK, Sim FJ, Goldman SA. Prospective identification, isolation, and profiling of a telomerase-expressing subpopulation of human neural stem cells, using sox2 enhancer-directed fluorescence-activated cell sorting. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 14635-48. PMID 21048121 DOI: 10.1523/JNEUROSCI.1729-10.2010  0.342
2010 Konopka G, Geschwind DH. Human brain evolution: harnessing the genomics (r)evolution to link genes, cognition, and behavior. Neuron. 68: 231-44. PMID 20955931 DOI: 10.1016/j.neuron.2010.10.012  0.597
2010 Anney R, Klei L, Pinto D, Regan R, Conroy J, Magalhaes TR, Correia C, Abrahams BS, Sykes N, Pagnamenta AT, Almeida J, Bacchelli E, Bailey AJ, Baird G, Battaglia A, ... ... Geschwind DH, et al. A genome-wide scan for common alleles affecting risk for autism. Human Molecular Genetics. 19: 4072-82. PMID 20663923 DOI: 10.1093/Hmg/Ddq307  0.707
2010 Miller JA, Horvath S, Geschwind DH. Divergence of human and mouse brain transcriptome highlights Alzheimer disease pathways. Proceedings of the National Academy of Sciences of the United States of America. 107: 12698-703. PMID 20616000 DOI: 10.1073/Pnas.0914257107  0.557
2010 Pinto D, Pagnamenta AT, Klei L, Anney R, Merico D, Regan R, Conroy J, Magalhaes TR, Correia C, Abrahams BS, Almeida J, Bacchelli E, Bader GD, Bailey AJ, Baird G, ... ... Geschwind DH, et al. Functional impact of global rare copy number variation in autism spectrum disorders. Nature. 466: 368-72. PMID 20531469 DOI: 10.1038/Nature09146  0.78
2010 Panaitof SC, Abrahams BS, Dong H, Geschwind DH, White SA. Language-related Cntnap2 gene is differentially expressed in sexually dimorphic song nuclei essential for vocal learning in songbirds. The Journal of Comparative Neurology. 518: 1995-2018. PMID 20394055 DOI: 10.1002/Cne.22318  0.682
2010 Abrahams BS, Geschwind DH. Connecting genes to brain in the autism spectrum disorders. Archives of Neurology. 67: 395-9. PMID 20385903 DOI: 10.1001/Archneurol.2010.47  0.748
2010 Ross ME, Geschwind D. Genes and the long and winding road to cortical construction and cognition. Neurobiology of Disease. 38: 145-7. PMID 20381768 DOI: 10.1016/j.nbd.2010.03.004  0.37
2010 Strom SP, Stone JL, Ten Bosch JR, Merriman B, Cantor RM, Geschwind DH, Nelson SF. High-density SNP association study of the 17q21 chromosomal region linked to autism identifies CACNA1G as a novel candidate gene. Molecular Psychiatry. 15: 996-1005. PMID 19455149 DOI: 10.1038/mp.2009.41  0.333
2010 Voineagu I, Gao F, Horvath S, Geschwind D. [P2.57]: Identification of shared molecular pathways involved in autism by brain transcriptome profiling International Journal of Developmental Neuroscience. 28: 706-706. DOI: 10.1016/j.ijdevneu.2010.07.187  0.354
2009 Konopka G, Bomar JM, Winden K, Coppola G, Jonsson ZO, Gao F, Peng S, Preuss TM, Wohlschlegel JA, Geschwind DH. Human-specific transcriptional regulation of CNS development genes by FOXP2. Nature. 462: 213-7. PMID 19907493 DOI: 10.1038/Nature08549  0.793
2009 Geschwind DH, Konopka G. Neuroscience in the era of functional genomics and systems biology. Nature. 461: 908-15. PMID 19829370 DOI: 10.1038/nature08537  0.596
2009 Winden KD, Oldham MC, Mirnics K, Ebert PJ, Swan CH, Levitt P, Rubenstein JL, Horvath S, Geschwind DH. The organization of the transcriptional network in specific neuronal classes. Molecular Systems Biology. 5: 291. PMID 19638972 DOI: 10.1038/Msb.2009.46  0.738
2009 Bucan M, Abrahams BS, Wang K, Glessner JT, Herman EI, Sonnenblick LI, Alvarez Retuerto AI, Imielinski M, Hadley D, Bradfield JP, Kim C, Gidaya NB, Lindquist I, Hutman T, Sigman M, ... ... Geschwind DH, et al. Genome-wide analyses of exonic copy number variants in a family-based study point to novel autism susceptibility genes. Plos Genetics. 5: e1000536. PMID 19557195 DOI: 10.1371/Journal.Pgen.1000536  0.745
2009 Zai L, Ferrari C, Subbaiah S, Havton LA, Coppola G, Strittmatter S, Irwin N, Geschwind D, Benowitz LI. Inosine alters gene expression and axonal projections in neurons contralateral to a cortical infarct and improves skilled use of the impaired limb. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 8187-97. PMID 19553458 DOI: 10.1523/Jneurosci.0414-09.2009  0.324
2009 Bill BR, Geschwind DH. Genetic advances in autism: heterogeneity and convergence on shared pathways. Current Opinion in Genetics & Development. 19: 271-8. PMID 19477629 DOI: 10.1016/J.Gde.2009.04.004  0.776
2009 Johnson MB, Kawasawa YI, Mason CE, Krsnik Z, Coppola G, Bogdanovi? D, Geschwind DH, Mane SM, State MW, Sestan N. Functional and evolutionary insights into human brain development through global transcriptome analysis. Neuron. 62: 494-509. PMID 19477152 DOI: 10.1016/J.Neuron.2009.03.027  0.624
2009 Wexler EM, Paucer A, Kornblum HI, Palmer TD, Plamer TD, Geschwind DH. Endogenous Wnt signaling maintains neural progenitor cell potency. Stem Cells (Dayton, Ohio). 27: 1130-41. PMID 19418460 DOI: 10.1002/stem.36  0.726
2009 Wang K, Zhang H, Ma D, Bucan M, Glessner JT, Abrahams BS, Salyakina D, Imielinski M, Bradfield JP, Sleiman PM, Kim CE, Hou C, Frackelton E, Chiavacci R, Takahashi N, ... ... Geschwind DH, et al. Common genetic variants on 5p14.1 associate with autism spectrum disorders. Nature. 459: 528-33. PMID 19404256 DOI: 10.1038/Nature07999  0.789
2009 Kumar RA, Marshall CR, Badner JA, Babatz TD, Mukamel Z, Aldinger KA, Sudi J, Brune CW, Goh G, Karamohamed S, Sutcliffe JS, Cook EH, Geschwind DH, Dobyns WB, Scherer SW, et al. Association and mutation analyses of 16p11.2 autism candidate genes. Plos One. 4: e4582. PMID 19242545 DOI: 10.1371/Journal.Pone.0004582  0.395
2009 Nagahara AH, Merrill DA, Coppola G, Tsukada S, Schroeder BE, Shaked GM, Wang L, Blesch A, Kim A, Conner JM, Rockenstein E, Chao MV, Koo EH, Geschwind D, Masliah E, et al. Neuroprotective effects of brain-derived neurotrophic factor in rodent and primate models of Alzheimer's disease. Nature Medicine. 15: 331-7. PMID 19198615 DOI: 10.1038/Nm.1912  0.329
2009 Coppola G, Winden K, Konopka G, Gao F, Geschwind D. Expression and network analysis of Illumina microarray data Nature Protocols. DOI: 10.1038/Nprot.2009.215  0.778
2008 Loat CS, Curran S, Lewis CM, Duvall J, Geschwind D, Bolton P, Craig IW. Methyl-CpG-binding protein 2 polymorphisms and vulnerability to autism. Genes, Brain, and Behavior. 7: 754-60. PMID 19125863 DOI: 10.1111/J.1601-183X.2008.00414.X  0.346
2008 Vernes SC, Newbury DF, Abrahams BS, Winchester L, Nicod J, Groszer M, Alarcón M, Oliver PL, Davies KE, Geschwind DH, Monaco AP, Fisher SE. A functional genetic link between distinct developmental language disorders. The New England Journal of Medicine. 359: 2337-45. PMID 18987363 DOI: 10.1056/Nejmoa0802828  0.7
2008 Geschwind DH. Autism: many genes, common pathways? Cell. 135: 391-5. PMID 18984147 DOI: 10.1016/j.cell.2008.10.016  0.337
2008 Karsten SL, Kudo LC, Geschwind DH. Gene expression analysis of neural cells and tissues using DNA microarrays. Current Protocols in Neuroscience / Editorial Board, Jacqueline N. Crawley ... [Et Al.]. Unit 4.28. PMID 18972379 DOI: 10.1002/0471142301.Ns0428S45  0.714
2008 Oldham MC, Konopka G, Iwamoto K, Langfelder P, Kato T, Horvath S, Geschwind DH. Functional organization of the transcriptome in human brain. Nature Neuroscience. 11: 1271-82. PMID 18849986 DOI: 10.1038/nn.2207  0.624
2008 Alvarez Retuerto AI, Cantor RM, Gleeson JG, Ustaszewska A, Schackwitz WS, Pennacchio LA, Geschwind DH. Association of common variants in the Joubert syndrome gene (AHI1) with autism. Human Molecular Genetics. 17: 3887-96. PMID 18782849 DOI: 10.1093/Hmg/Ddn291  0.385
2008 Abrahams BS, Geschwind DH. Advances in autism genetics: on the threshold of a new neurobiology. Nature Reviews. Genetics. 9: 341-55. PMID 18414403 DOI: 10.1038/Nrg2346  0.733
2008 Krystal JH, Carter CS, Geschwind D, Manji HK, March JS, Nestler EJ, Zubieta JK, Charney DS, Goldman D, Gur RE, Lieberman JA, Roy-Byrne P, Rubinow DR, Anderson SA, Barondes S, et al. It is time to take a stand for medical research and against terrorism targeting medical scientists. Biological Psychiatry. 63: 725-7. PMID 18371494 DOI: 10.1016/J.Biopsych.2008.03.005  0.4
2008 Miller JA, Oldham MC, Geschwind DH. A systems level analysis of transcriptional changes in Alzheimer's disease and normal aging. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 1410-20. PMID 18256261 DOI: 10.1523/Jneurosci.4098-07.2008  0.515
2008 Bakkaloglu B, O'Roak BJ, Louvi A, Gupta AR, Abelson JF, Morgan TM, Chawarska K, Klin A, Ercan-Sencicek AG, Stillman AA, Tanriover G, Abrahams BS, Duvall JA, Robbins EM, Geschwind DH, et al. Molecular cytogenetic analysis and resequencing of contactin associated protein-like 2 in autism spectrum disorders. American Journal of Human Genetics. 82: 165-73. PMID 18179895 DOI: 10.1016/J.Ajhg.2007.09.017  0.786
2008 Alarcón M, Abrahams BS, Stone JL, Duvall JA, Perederiy JV, Bomar JM, Sebat J, Wigler M, Martin CL, Ledbetter DH, Nelson SF, Cantor RM, Geschwind DH. Linkage, association, and gene-expression analyses identify CNTNAP2 as an autism-susceptibility gene. American Journal of Human Genetics. 82: 150-9. PMID 18179893 DOI: 10.1016/J.Ajhg.2007.09.005  0.748
2008 Wexler EM, Geschwind DH, Palmer TD. Lithium regulates adult hippocampal progenitor development through canonical Wnt pathway activation. Molecular Psychiatry. 13: 285-92. PMID 17968353 DOI: 10.1038/sj.mp.4002093  0.728
2008 Geschwind D. S2-03-04: Role of aminopeptidase NPPS in tauopathy Alzheimers & Dementia. 4. DOI: 10.1016/J.Jalz.2008.05.286  0.316
2008 Lu P, Thompson P, Leow A, Lee G, Lee A, Geschwind D, Stewart S, Bartzokis G. IC-P3-197: Apolipoprotein genotype predicts rate of brain atrophy in healthy elderly adults: A tensor-based morphometry study Alzheimers & Dementia. 4. DOI: 10.1016/J.Jalz.2008.05.141  0.364
2008 Geschwind D. [SY2.0]: Autism: from gene to brain to behavior International Journal of Developmental Neuroscience. 26: 830-830. DOI: 10.1016/j.ijdevneu.2008.09.018  0.373
2007 Wexler EM, Geschwind DH. Out FOXing Parkinson disease: where development meets neurodegeneration. Plos Biology. 5: e334. PMID 18092892 DOI: 10.1371/journal.pbio.0050334  0.618
2007 Vernes SC, Spiteri E, Nicod J, Groszer M, Taylor JM, Davies KE, Geschwind DH, Fisher SE. High-throughput analysis of promoter occupancy reveals direct neural targets of FOXP2, a gene mutated in speech and language disorders. American Journal of Human Genetics. 81: 1232-50. PMID 17999362 DOI: 10.1086/522238  0.341
2007 Spiteri E, Konopka G, Coppola G, Bomar J, Oldham M, Ou J, Vernes SC, Fisher SE, Ren B, Geschwind DH. Identification of the transcriptional targets of FOXP2, a gene linked to speech and language, in developing human brain. American Journal of Human Genetics. 81: 1144-57. PMID 17999357 DOI: 10.1086/522237  0.614
2007 Abrahams BS, Tentler D, Perederiy JV, Oldham MC, Coppola G, Geschwind DH. Genome-wide analyses of human perisylvian cerebral cortical patterning. Proceedings of the National Academy of Sciences of the United States of America. 104: 17849-54. PMID 17978184 DOI: 10.1073/Pnas.0706128104  0.735
2007 Geschwind D. Autism: searching for coherence. Biological Psychiatry. 62: 949-50. PMID 17950066 DOI: 10.1016/j.biopsych.2007.09.001  0.367
2007 Francks C, Maegawa S, Laurén J, Abrahams BS, Velayos-Baeza A, Medland SE, Colella S, Groszer M, McAuley EZ, Caffrey TM, Timmusk T, Pruunsild P, Koppel I, Lind PA, Matsumoto-Itaba N, ... ... Geschwind DH, et al. LRRTM1 on chromosome 2p12 is a maternally suppressed gene that is associated paternally with handedness and schizophrenia. Molecular Psychiatry. 12: 1129-39, 1057. PMID 17667961 DOI: 10.1038/Sj.Mp.4002053  0.743
2007 Nishimura Y, Martin CL, Vazquez-Lopez A, Spence SJ, Alvarez-Retuerto AI, Sigman M, Steindler C, Pellegrini S, Schanen NC, Warren ST, Geschwind DH. Genome-wide expression profiling of lymphoblastoid cell lines distinguishes different forms of autism and reveals shared pathways. Human Molecular Genetics. 16: 1682-98. PMID 17519220 DOI: 10.1093/Hmg/Ddm116  0.389
2007 Martin CL, Duvall JA, Ilkin Y, Simon JS, Arreaza MG, Wilkes K, Alvarez-Retuerto A, Whichello A, Powell CM, Rao K, Cook E, Geschwind DH. Cytogenetic and molecular characterization of A2BP1/FOX1 as a candidate gene for autism. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 144: 869-76. PMID 17503474 DOI: 10.1002/ajmg.b.30530  0.348
2007 Nakano I, Dougherty JD, Kim K, Klement I, Geschwind DH, Kornblum HI. Phosphoserine phosphatase is expressed in the neural stem cell niche and regulates neural stem and progenitor cell proliferation. Stem Cells (Dayton, Ohio). 25: 1975-84. PMID 17495110 DOI: 10.1634/Stemcells.2007-0046  0.511
2007 Szatmari P, Paterson AD, Zwaigenbaum L, Roberts W, Brian J, Liu XQ, Vincent JB, Skaug JL, Thompson AP, Senman L, Feuk L, Qian C, Bryson SE, Jones MB, ... ... Geschwind DH, et al. Mapping autism risk loci using genetic linkage and chromosomal rearrangements. Nature Genetics. 39: 319-28. PMID 17322880 DOI: 10.1038/Ng1985  0.602
2007 Geschwind DH, Levitt P. Autism spectrum disorders: developmental disconnection syndromes. Current Opinion in Neurobiology. 17: 103-11. PMID 17275283 DOI: 10.1016/j.conb.2007.01.009  0.307
2007 Kudo LC, Karsten SL, Chen J, Levitt P, Geschwind DH. Genetic analysis of anterior posterior expression gradients in the developing mammalian forebrain. Cerebral Cortex (New York, N.Y. : 1991). 17: 2108-22. PMID 17150988 DOI: 10.1093/Cercor/Bhl118  0.755
2006 Coppola G, Geschwind DH. Technology Insight: querying the genome with microarrays--progress and hope for neurological disease. Nature Clinical Practice. Neurology. 2: 147-58. PMID 16932541 DOI: 10.1038/ncpneuro0133  0.338
2006 Geschwind D. From genes to neurons to brain. Genes, Brain, and Behavior. 5: 1-4. PMID 16681796 DOI: 10.1111/j.1601-183X.2006.00222.x  0.355
2006 Coppola G, Choi SH, Santos MM, Miranda CJ, Tentler D, Wexler EM, Pandolfo M, Geschwind DH. Gene expression profiling in frataxin deficient mice: microarray evidence for significant expression changes without detectable neurodegeneration. Neurobiology of Disease. 22: 302-11. PMID 16442805 DOI: 10.1016/j.nbd.2005.11.014  0.688
2006 Groszer M, Erickson R, Scripture-Adams DD, Dougherty JD, Le Belle J, Zack JA, Geschwind DH, Liu X, Kornblum HI, Wu H. PTEN negatively regulates neural stem cell self-renewal by modulating G0-G1 cell cycle entry. Proceedings of the National Academy of Sciences of the United States of America. 103: 111-6. PMID 16373498 DOI: 10.1073/Pnas.0509939103  0.522
2006 Chen GK, Kono N, Geschwind DH, Cantor RM. Quantitative trait locus analysis of nonverbal communication in autism spectrum disorder. Molecular Psychiatry. 11: 214-20. PMID 16189504 DOI: 10.1038/sj.mp.4001753  0.321
2006 Sebat J, Lakshmi B, Troge J, Martin C, Spence S, Ledbetter D, Gilliam TC, Ye K, Geschwind D, Sutcliffe J, Wigler MH. High-resolution analysis of genome copy number variation in autism International Journal of Developmental Neuroscience. 24: 474. DOI: 10.1016/J.Ijdevneu.2006.09.013  0.326
2006 Geschwind D. [S9]: Deciphering complexity in autism genetics: Endophenotypes and pathway analysis International Journal of Developmental Neuroscience. 24: 474-474. DOI: 10.1016/j.ijdevneu.2006.09.012  0.337
2005 Dougherty JD, Garcia AD, Nakano I, Livingstone M, Norris B, Polakiewicz R, Wexler EM, Sofroniew MV, Kornblum HI, Geschwind DH. PBK/TOPK, a proliferating neural progenitor-specific mitogen-activated protein kinase kinase. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 10773-85. PMID 16291951 DOI: 10.1523/Jneurosci.3207-05.2005  0.723
2005 Nakano I, Paucar AA, Bajpai R, Dougherty JD, Zewail A, Kelly TK, Kim KJ, Ou J, Groszer M, Imura T, Freije WA, Nelson SF, Sofroniew MV, Wu H, Liu X, ... ... Geschwind DH, et al. Maternal embryonic leucine zipper kinase (MELK) regulates multipotent neural progenitor proliferation. The Journal of Cell Biology. 170: 413-27. PMID 16061694 DOI: 10.1083/Jcb.200412115  0.546
2005 Dougherty JD, Geschwind DH. Progress in realizing the promise of microarrays in systems neurobiology. Neuron. 45: 183-5. PMID 15664168 DOI: 10.1016/J.Neuron.2005.01.007  0.522
2004 Karsten SL, Kudo LC, Geschwind DH. Microarray platforms: introduction and application to neurobiology. International Review of Neurobiology. 60: 1-23. PMID 15474585 DOI: 10.1016/S0074-7742(04)60001-8  0.714
2004 Jen JC, Chan WM, Bosley TM, Wan J, Carr JR, Rüb U, Shattuck D, Salamon G, Kudo LC, Ou J, Lin DD, Salih MA, Kansu T, Al Dhalaan H, Al Zayed Z, ... ... Geschwind DH, et al. Mutations in a human ROBO gene disrupt hindbrain axon pathway crossing and morphogenesis. Science (New York, N.Y.). 304: 1509-13. PMID 15105459 DOI: 10.1126/Science.1096437  0.698
2004 Teramitsu I, Kudo LC, London SE, Geschwind DH, White SA. Parallel FoxP1 and FoxP2 expression in songbird and human brain predicts functional interaction. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 3152-63. PMID 15056695 DOI: 10.1523/Jneurosci.5589-03.2004  0.74
2004 Hedlund E, Karsten SL, Kudo L, Geschwind DH, Carpenter EM. Identification of a Hoxd10-regulated transcriptional network and combinatorial interactions with Hoxa10 during spinal cord development. Journal of Neuroscience Research. 75: 307-19. PMID 14743444 DOI: 10.1002/Jnr.10844  0.748
2003 Easterday MC, Dougherty JD, Jackson RL, Ou J, Nakano I, Paucar AA, Roobini B, Dianati M, Irvin DK, Weissman IL, Terskikh AV, Geschwind DH, Kornblum HI. Neural progenitor genes. Germinal zone expression and analysis of genetic overlap in stem cell populations. Developmental Biology. 264: 309-22. PMID 14651920 DOI: 10.1016/J.Ydbio.2003.09.003  0.811
2003 Simpson JL, de la Cruz F, Swerdloff RS, Samango-Sprouse C, Skakkebaek NE, Graham JM, Hassold T, Aylstock M, Meyer-Bahlburg HF, Willard HF, Hall JG, Salameh W, Boone K, Staessen C, Geschwind D, et al. Klinefelter syndrome: expanding the phenotype and identifying new research directions. Genetics in Medicine : Official Journal of the American College of Medical Genetics. 5: 460-8. PMID 14614399 DOI: 10.1097/01.Gim.0000095626.54201.D0  0.302
2003 Cáceres M, Lachuer J, Zapala MA, Redmond JC, Kudo L, Geschwind DH, Lockhart DJ, Preuss TM, Barlow C. Elevated gene expression levels distinguish human from non-human primate brains. Proceedings of the National Academy of Sciences of the United States of America. 100: 13030-5. PMID 14557539 DOI: 10.1073/Pnas.2135499100  0.749
2003 Karsten SL, Kudo LC, Jackson R, Sabatti C, Kornblum HI, Geschwind DH. Global analysis of gene expression in neural progenitors reveals specific cell-cycle, signaling, and metabolic networks. Developmental Biology. 261: 165-82. PMID 12941627 DOI: 10.1016/S0012-1606(03)00274-4  0.746
2003 Geschwind DH. DNA microarrays: translation of the genome from laboratory to clinic. The Lancet. Neurology. 2: 275-82. PMID 12849181  0.326
2002 Ohira R, Zhang YH, Guo W, Dipple K, Shih SL, Doerr J, Huang BL, Fu LJ, Abu-Khalil A, Geschwind D, McCabe ER. Human ARX gene: genomic characterization and expression. Molecular Genetics and Metabolism. 77: 179-88. PMID 12359145 DOI: 10.1016/S1096-7192(02)00126-9  0.441
2002 Dougherty JD, Geschwind DH. Subtraction-coupled custom microarray analysis for gene discovery and gene expression studies in the CNS. Chemical Senses. 27: 293-8. PMID 11923191 DOI: 10.1093/Chemse/27.3.293  0.572
2001 Liu J, Nyholt DR, Magnussen P, Parano E, Pavone P, Geschwind D, Lord C, Iversen P, Hoh J, Ott J, Gilliam TC. A genomewide screen for autism susceptibility loci. American Journal of Human Genetics. 69: 327-40. PMID 11452361 DOI: 10.1086/321980  0.345
2001 Terskikh AV, Easterday MC, Li L, Hood L, Kornblum HI, Geschwind DH, Weissman IL. From hematopoiesis to neuropoiesis: evidence of overlapping genetic programs. Proceedings of the National Academy of Sciences of the United States of America. 98: 7934-9. PMID 11438738 DOI: 10.1046/J.1471-4159.81.S1.105.X  0.803
2001 Geschwind DH, Ou J, Easterday MC, Dougherty JD, Jackson RL, Chen Z, Antoine H, Terskikh A, Weissman IL, Nelson SF, Kornblum HI. A genetic analysis of neural progenitor differentiation. Neuron. 29: 325-39. PMID 11239426 DOI: 10.1016/S0896-6273(01)00209-4  0.816
2001 Wilhelmsen KC, Miller B, Geschwind D. Neuronal subpopulations and genetic background in tauopathies: A catch 22 story? Commentary Neurobiology of Aging. 22: 119-121. PMID 11164284 DOI: 10.1016/S0197-4580(00)00198-6  0.304
1989 Geschwind D, Hockfield S. Identification of proteins that are developmentally regulated during early cerebral corticogenesis in the rat. The Journal of Neuroscience. 9: 4303-4317. DOI: 10.1523/Jneurosci.09-12-04303.1989  0.612
Show low-probability matches.