James Huettner, Ph.D. - Publications

Cell Biology Washington University, Saint Louis, St. Louis, MO 
glutamate receptors, stem cells

80 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Strong KL, Epplin MP, Ogden KK, Burger PB, Kaiser TM, Wilding TJ, Kusumoto H, Camp CR, Shaulsky G, Bhattacharya S, Perszyk RE, Menaldino DS, McDaniel MJ, Zhang J, Le P, ... ... Huettner JE, et al. Distinct GluN1 and GluN2 Structural Determinants for Subunit-Selective Positive Allosteric Modulation of -Methyl-d-aspartate Receptors. Acs Chemical Neuroscience. PMID 33326224 DOI: 10.1021/acschemneuro.0c00561  1
2020 Wilding TJ, Huettner JE. Cadmium activates AMPA and NMDA receptors with M3 helix cysteine substitutions. The Journal of General Physiology. 152. PMID 32342094 DOI: 10.1085/jgp.201912537  1
2018 Wilding TJ, Huettner JE. Cadmium opens GluK2 kainate receptors with cysteine substitutions at the M3 helix bundle crossing. The Journal of General Physiology. PMID 30498132 DOI: 10.1085/jgp.201812234  1
2018 Chisari M, Wilding TJ, Brunwasser S, Krishnan K, Qian M, Benz A, Huettner JE, Zorumski CF, Covey DF, Mennerick S. Visualizing pregnenolone sulfate-like modulators of NMDA receptor function reveals intracellular and plasma-membrane localization. Neuropharmacology. PMID 30332607 DOI: 10.1016/J.Neuropharm.2018.10.015  1
2017 Meganathan K, Lewis EMA, Gontarz P, Liu S, Stanley EG, Elefanty AG, Huettner JE, Zhang B, Kroll KL. Regulatory networks specifying cortical interneurons from human embryonic stem cells reveal roles for CHD2 in interneuron development. Proceedings of the National Academy of Sciences of the United States of America. PMID 29229852 DOI: 10.1073/pnas.1712365115  0.01
2017 Yang DM, Huettner JE, Bretthorst GL, Neil JJ, Garbow JR, Ackerman JJH. Intracellular water preexchange lifetime in neurons and astrocytes. Magnetic Resonance in Medicine. PMID 28675497 DOI: 10.1002/Mrm.26781  0.01
2017 Huettner JE. TARPs and AMPA Receptors: Function Follows Form. Neuron. 93: 989-991. PMID 28279361 DOI: 10.1016/j.neuron.2017.02.040  0.01
2016 Wilding TJ, Lopez MN, Huettner JE. Chimeric Glutamate Receptor Subunits Reveal the Transmembrane Domain Is Sufficient for NMDA Receptor Pore Properties but Some Positive Allosteric Modulators Require Additional Domains. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 8815-25. PMID 27559165 DOI: 10.1523/JNEUROSCI.0345-16.2016  1
2016 Iyer NR, Huettner JE, Butts JC, Brown CR, Sakiyama-Elbert SE. Generation of Highly Enriched V2a Interneurons from Mouse Embryonic Stem Cells. Experimental Neurology. PMID 26784005 DOI: 10.1016/J.Expneurol.2016.01.011  1
2015 Xu H, Iyer N, Huettner JE, Sakiyama-Elbert SE. A puromycin selectable cell line for the enrichment of mouse embryonic stem cell-derived V3 interneurons. Stem Cell Research & Therapy. 6: 220. PMID 26555777 DOI: 10.1186/S13287-015-0213-Z  1
2015 Huber S, Huettner JP, Hacker K, Bernhardt G, König J, Buschauer A. Esters of Bendamustine Are by Far More Potent Cytotoxic Agents than the Parent Compound against Human Sarcoma and Carcinoma Cells. Plos One. 10: e0133743. PMID 26196503 DOI: 10.1371/journal.pone.0133743  1
2015 Huettner JE. Glutamate receptor pores. The Journal of Physiology. 593: 49-59. PMID 25556787 DOI: 10.1113/jphysiol.2014.272724  1
2015 Broady E, Huettner J, Pachler N, Wingate U. Editorial Language Learning Journal. 43: 1-5. DOI: 10.1080/09571736.2014.997459  1
2014 McCreedy DA, Brown CR, Butts JC, Xu H, Huettner JE, Sakiyama-Elbert SE. A new method for generating high purity motoneurons from mouse embryonic stem cells. Biotechnology and Bioengineering. 111: 2041-55. PMID 24842774 DOI: 10.1002/Bit.25260  1
2014 Huettner JE. Vertebrate galectins: endogenous regulators of ionotropic glutamate receptors? The Journal of Physiology. 592: 2035-6. PMID 24833729 DOI: 10.1113/jphysiol.2014.273920  1
2014 Huettner JE. Glutamate receptor pores. The Journal of Physiology. PMID 24710063 DOI: 10.1113/jphysiol.2014.272724  0.01
2014 Wilding TJ, Lopez MN, Huettner JE. Radial symmetry in a chimeric glutamate receptor pore. Nature Communications. 5: 3349. PMID 24561802 DOI: 10.1038/ncomms4349  1
2014 Schramm A, Schinner E, Huettner JP, Kees F, Tauber P, Hofmann F, Schlossmann J. Function of cGMP-dependent protein kinase II in volume load-induced diuresis. PflüGers Archiv : European Journal of Physiology. 466: 2009-18. PMID 24442122 DOI: 10.1007/s00424-014-1445-y  1
2013 Wolfertstetter S, Huettner JP, Schlossmann J. cGMP-Dependent Protein Kinase Inhibitors in Health and Disease. Pharmaceuticals (Basel, Switzerland). 6: 269-86. PMID 24275951 DOI: 10.3390/ph6020269  1
2013 Chandrasekar I, Huettner JE, Turney SG, Bridgman PC. Myosin II regulates activity dependent compensatory endocytosis at central synapses. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 16131-45. PMID 24107946 DOI: 10.1523/Jneurosci.2229-13.2013  1
2013 Lopez MN, Wilding TJ, Huettner JE. Q/R site interactions with the M3 helix in GluK2 kainate receptor channels revealed by thermodynamic mutant cycles. The Journal of General Physiology. 142: 225-39. PMID 23940260 DOI: 10.1085/jgp.201311000  1
2013 McDonald JW, Becker D, Huettner J. Spinal Cord Injury Handbook of Stem Cells. 2: 723-738. DOI: 10.1016/B978-0-12-385942-6.00062-7  1
2012 Huettner J, Kurz F, Metz G, Ziroff A. Lightweight power line communications for Smart Grid applications with standard RFID tags Globecom - Ieee Global Telecommunications Conference. 3165-3170. DOI: 10.1109/GLOCOM.2012.6503601  1
2011 Solomon IH, Khatri N, Biasini E, Massignan T, Huettner JE, Harris DA. An N-terminal polybasic domain and cell surface localization are required for mutant prion protein toxicity. The Journal of Biological Chemistry. 286: 14724-36. PMID 21385869 DOI: 10.1074/Jbc.M110.214973  1
2011 Gierlich R, Huettner J, Ziroff A, Weigel R, Huemer M. A reconfigurable MIMO system for high-precision FMCW local positioning Ieee Transactions On Microwave Theory and Techniques. 59: 3228-3238. DOI: 10.1109/TMTT.2011.2169079  1
2010 Wilding TJ, Chen K, Huettner JE. Fatty acid modulation and polyamine block of GluK2 kainate receptors analyzed by scanning mutagenesis. The Journal of General Physiology. 136: 339-52. PMID 20805577 DOI: 10.1085/jgp.201010442  1
2010 Solomon IH, Huettner JE, Harris DA. Neurotoxic mutants of the prion protein induce spontaneous ionic currents in cultured cells. The Journal of Biological Chemistry. 285: 26719-26. PMID 20573963 DOI: 10.1074/Jbc.M110.134619  1
2009 Webb AB, Angelo N, Huettner JE, Herzog ED. Intrinsic, nondeterministic circadian rhythm generation in identified mammalian neurons. Proceedings of the National Academy of Sciences of the United States of America. 106: 16493-8. PMID 19805326 DOI: 10.1073/Pnas.0902768106  1
2009 Kim M, Habiba A, Doherty JM, Mills JC, Mercer RW, Huettner JE. Regulation of mouse embryonic stem cell neural differentiation by retinoic acid. Developmental Biology. 328: 456-71. PMID 19217899 DOI: 10.1016/J.Ydbio.2009.02.001  1
2009 Huettner J, Gierlich R, Ziroff A, Weigel R. A low cost Ultra-Wide-Band Pulse Radar in a guided wave gauging application European Microwave Week 2009, Eumw 2009: Science, Progress and Quality At Radiofrequencies, Conference Proceedings - 6th European Radar Conference, Eurad 2009. 101-104.  1
2008 Laezza F, Wilding TJ, Sequeira S, Craig AM, Huettner JE. The BTB/kelch protein, KRIP6, modulates the interaction of PICK1 with GluR6 kainate receptors. Neuropharmacology. 55: 1131-9. PMID 18692513 DOI: 10.1016/J.Neuropharm.2008.07.021  1
2008 Wilding TJ, Fulling E, Zhou Y, Huettner JE. Amino acid substitutions in the pore helix of GluR6 control inhibition by membrane fatty acids. The Journal of General Physiology. 132: 85-99. PMID 18562501 DOI: 10.1085/jgp.200810009  1
2007 Laezza F, Wilding TJ, Sequeira S, Coussen F, Zhang XZ, Hill-Robinson R, Mulle C, Huettner JE, Craig AM. KRIP6: a novel BTB/kelch protein regulating function of kainate receptors. Molecular and Cellular Neurosciences. 34: 539-50. PMID 17254796 DOI: 10.1016/J.Mcn.2006.12.003  1
2006 Aton SJ, Huettner JE, Straume M, Herzog ED. GABA and Gi/o differentially control circadian rhythms and synchrony in clock neurons. Proceedings of the National Academy of Sciences of the United States of America. 103: 19188-93. PMID 17138670 DOI: 10.1073/Pnas.0607466103  1
2006 Drenan RM, Doupnik CA, Jayaraman M, Buchwalter AL, Kaltenbronn KM, Huettner JE, Linder ME, Blumer KJ. R7BP augments the function of RGS7*Gbeta5 complexes by a plasma membrane-targeting mechanism. The Journal of Biological Chemistry. 281: 28222-31. PMID 16867977 DOI: 10.1074/Jbc.M604428200  1
2006 Huettner JE, Lu A, Qu Y, Wu Y, Kim M, McDonald JW. Gap junctions and connexon hemichannels in human embryonic stem cells. Stem Cells (Dayton, Ohio). 24: 1654-67. PMID 16574755 DOI: 10.1634/Stemcells.2005-0003  1
2006 Huettner J, Reinhardt S, Huemer M. Low complex IQ-imbalance compensation for low-IF receivers Proceedings - 2006 Ieee Radio and Wireless Symposium. 2006: 303-306.  1
2005 Wilding TJ, Zhou Y, Huettner JE. Q/R site editing controls kainate receptor inhibition by membrane fatty acids. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 9470-8. PMID 16221857 DOI: 10.1523/JNEUROSCI.2826-05.2005  1
2005 Leevy WM, Gammon ST, Levchenko T, Daranciang DD, Murillo O, Torchilin V, Piwnica-Worms D, Huettner JE, Gokel GW. Structure-activity relationships, kinetics, selectivity, and mechanistic studies of synthetic hydraphile channels in bacterial and mammalian cells. Organic & Biomolecular Chemistry. 3: 3544-50. PMID 16172693 DOI: 10.1039/B508157B  1
2005 Drenan RM, Doupnik CA, Boyle MP, Muglia LJ, Huettner JE, Linder ME, Blumer KJ. Palmitoylation regulates plasma membrane-nuclear shuttling of R7BP, a novel membrane anchor for the RGS7 family. The Journal of Cell Biology. 169: 623-33. PMID 15897264 DOI: 10.1083/Jcb.200502007  1
2004 Leevy WM, Huettner JE, Pajewski R, Schlesinger PH, Gokel GW. Synthetic ion channel activity documented by electrophysiological methods in living cells. Journal of the American Chemical Society. 126: 15747-53. PMID 15571397 DOI: 10.1021/Ja046626X  1
2003 Huettner JE. Spine-tingling excitement from glutamate receptors. Science's Stke : Signal Transduction Knowledge Environment. 2003: pe53. PMID 14645811 DOI: 10.1126/stke.2102003pe53  1
2003 Huettner JE. Kainate receptors and synaptic transmission. Progress in Neurobiology. 70: 387-407. PMID 14511698 DOI: 10.1016/S0301-0082(03)00122-9  1
2002 Kerchner GA, Wilding TJ, Huettner JE, Zhuo M. Kainate receptor subunits underlying presynaptic regulation of transmitter release in the dorsal horn. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 8010-7. PMID 12223554 DOI: 10.1523/Jneurosci.22-18-08010.2002  1
2002 Huettner JE, Kerchner GA, Zhuo M. Glutamate and the presynaptic control of spinal sensory transmission. The Neuroscientist : a Review Journal Bringing Neurobiology, Neurology and Psychiatry. 8: 89-92. PMID 11954562 DOI: 10.1177/107385840200800204  1
2001 Kerchner GA, Wang GD, Qiu CS, Huettner JE, Zhuo M. Direct presynaptic regulation of GABA/glycine release by kainate receptors in the dorsal horn: an ionotropic mechanism. Neuron. 32: 477-88. PMID 11709158 DOI: 10.1016/S0896-6273(01)00479-2  1
2001 Huettner JE. Kainate receptors: knocking out plasticity. Trends in Neurosciences. 24: 365-6. PMID 11410255 DOI: 10.1016/S0166-2236(00)01830-0  1
2001 Wilding TJ, Huettner JE. Functional diversity and developmental changes in rat neuronal kainate receptors. The Journal of Physiology. 532: 411-21. PMID 11306660 DOI: 10.1111/j.1469-7793.2001.0411f.x  1
2001 Kerchner GA, Wilding TJ, Li P, Zhuo M, Huettner JE. Presynaptic kainate receptors regulate spinal sensory transmission. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 59-66. PMID 11150320 DOI: 10.1523/Jneurosci.21-01-00059.2001  1
1999 Gottlieb DI, Huettner JE. An in vitro pathway from embryonic stem cells to neurons and glia. Cells, Tissues, Organs. 165: 165-72. PMID 10592388 DOI: 10.1159/000016696  1
1999 Li P, Kerchner GA, Sala C, Wei F, Huettner JE, Sheng M, Zhuo M. AMPA receptor-PDZ interactions in facilitation of spinal sensory synapses. Nature Neuroscience. 2: 972-7. PMID 10526335 DOI: 10.1038/14771  1
1999 Finley MF, Devata S, Huettner JE. BMP-4 inhibits neural differentiation of murine embryonic stem cells. Journal of Neurobiology. 40: 271-87. PMID 10440729 DOI: 10.1002/(SICI)1097-4695(19990905)40:3<271::AID-NEU1>3.0.CO;2-C  1
1999 Li P, Wilding TJ, Kim SJ, Calejesan AA, Huettner JE, Zhuo M. Kainate-receptor-mediated sensory synaptic transmission in mammalian spinal cord. Nature. 397: 161-4. PMID 9923678 DOI: 10.1038/16469  1
1998 Huettner JE, Stack E, Wilding TJ. Antagonism of neuronal kainate receptors by lanthanum and gadolinium. Neuropharmacology. 37: 1239-47. PMID 9849661 DOI: 10.1016/S0028-3908(98)00082-3  1
1998 Wilding TJ, Chai YH, Huettner JE. Inhibition of rat neuronal kainate receptors by cis-unsaturated fatty acids. The Journal of Physiology. 513: 331-9. PMID 9806986  1
1997 Jones KA, Wilding TJ, Huettner JE, Costa AM. Desensitization of kainate receptors by kainate, glutamate and diastereomers of 4-methylglutamate. Neuropharmacology. 36: 853-63. PMID 9225313 DOI: 10.1016/S0028-3908(97)00066-X  1
1997 Wilding TJ, Huettner JE. Activation and desensitization of hippocampal kainate receptors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 2713-21. PMID 9092592  1
1996 Guzikowski AP, Cai SX, Espitia SA, Hawkinson JE, Huettner JE, Nogales DF, Tran M, Woodward RM, Weber E, Keana JF. Analogs of 3-hydroxy-1H-1-benzazepine-2,5-dione: structure-activity relationship at N-methyl-D-aspartate receptor glycine sites. Journal of Medicinal Chemistry. 39: 4643-53. PMID 8917653 DOI: 10.1021/Jm960479Z  1
1996 Canzoniero LM, Sensi SL, Turetsky DM, Finley MF, Choi DW, Huettner JE. Glutamate receptor-mediated calcium entry in neurons derived from P19 embryonal carcinoma cells. Journal of Neuroscience Research. 45: 226-36. PMID 8841983 DOI: 10.1002/(Sici)1097-4547(19960801)45:3<226::Aid-Jnr4>3.0.Co;2-F  1
1996 Wilding TJ, Huettner JE. Antagonist pharmacology of kainate- and alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid-preferring receptors. Molecular Pharmacology. 49: 540-6. PMID 8643094  1
1996 Finley MF, Kulkarni N, Huettner JE. Synapse formation and establishment of neuronal polarity by P19 embryonic carcinoma cells and embryonic stem cells. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 16: 1056-65. PMID 8558234  1
1995 Woodward RM, Huettner JE, Tran M, Guastella J, Keana JF, Weber E. Pharmacology of 5-chloro-7-trifluoromethyl-1,4-dihydro-2,3-quinoxalinedione: a novel systemically active ionotropic glutamate receptor antagonist. The Journal of Pharmacology and Experimental Therapeutics. 275: 1209-18. PMID 8531083  1
1995 Bain G, Kitchens D, Yao M, Huettner JE, Gottlieb DI. Embryonic stem cells express neuronal properties in vitro. Developmental Biology. 168: 342-57. PMID 7729574 DOI: 10.1006/dbio.1995.1085  1
1995 Wilding TJ, Huettner JE. Differential antagonism of alpha-amino-3-hydroxy-5-methyl-4- isoxazolepropionic acid-preferring and kainate-preferring receptors by 2,3-benzodiazepines. Molecular Pharmacology. 47: 582-7. PMID 7700255  1
1995 Woodward RM, Huettner JE, Guastella J, Keana JF, Weber E. In vitro pharmacology of ACEA-1021 and ACEA-1031: systemically active quinoxalinediones with high affinity and selectivity for N-methyl-D-aspartate receptor glycine sites. Molecular Pharmacology. 47: 568-81. PMID 7700254  1
1994 Schensul SL, Eisenberg MR, Glasgow J, Huettner J. Translating state data into local programs: targeted research for intervention planning (TRIP) American Journal of Public Health. 84: 671-2. PMID 8154577 DOI: 10.2105/AJPH.84.4.671  1
1993 Turetsky DM, Huettner JE, Gottlieb DI, Goldberg MP, Choi DW. Glutamate receptor-mediated currents and toxicity in embryonal carcinoma cells. Journal of Neurobiology. 24: 1157-69. PMID 7691990 DOI: 10.1002/Neu.480240904  1
1992 Swartz KJ, Koroshetz WJ, Rees AH, Huettner JE. Competitive antagonism of glutamate receptor channels by substituted benzazepines in cultured cortical neurons. Molecular Pharmacology. 41: 1130-41. PMID 1352036  1
1991 Huettner JE. Competitive antagonism of glycine at the N-methyl-D-aspartate (NMDA) receptor. Biochemical Pharmacology. 41: 9-16. PMID 1824750 DOI: 10.1016/0006-2952(91)90004-O  1
1990 Huettner JE. Glutamate receptor channels in rat DRG neurons: activation by kainate and quisqualate and blockade of desensitization by Con A. Neuron. 5: 255-66. PMID 2169266 DOI: 10.1016/0896-6273(90)90163-A  1
1990 Huettner JE. Antagonists of NMDA-activated current in cortical neurons: competition with glycine and blockade of open channels. Advances in Experimental Medicine and Biology. 268: 35-43. PMID 2150155  1
1990 Davis WL, Schmid KO, Huettner JW, Farmer GR, Jacoby BH, Goodman DB. Immunolocalization of secretory protein-I or chromogranin A in amphibian urinary bladder granular cell granules. Cell Biology International Reports. 14: 601-12. PMID 2118425 DOI: 10.1016/0309-1651(90)90040-6  1
1989 Huettner JE. Indole-2-carboxylic acid: a competitive antagonist of potentiation by glycine at the NMDA receptor. Science (New York, N.Y.). 243: 1611-3. PMID 2467381  1
1988 Huettner JE, Baughman RW. The pharmacology of synapses formed by identified corticocollicular neurons in primary cultures of rat visual cortex. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 8: 160-75. PMID 3339406 DOI: 10.1523/Jneurosci.08-01-00160.1988  1
1988 Huettner JE, Bean BP. Block of N-methyl-D-aspartate-activated current by the anticonvulsant MK-801: selective binding to open channels. Proceedings of the National Academy of Sciences of the United States of America. 85: 1307-11. PMID 2448800 DOI: 10.1073/Pnas.85.4.1307  1
1986 Huettner JE, Baughman RW. Primary culture of identified neurons from the visual cortex of postnatal rats. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 6: 3044-60. PMID 3760948 DOI: 10.1523/Jneurosci.06-10-03044.1986  1
1983 Briggs TG, Huettner J. Detection of the alcoholic patient in the acute care setting. Minnesota Medicine. 66: 245-8. PMID 6855740  1
1982 Eichhorn HJ, Huettner J. Influence of different individual doses and fractionation numbers on the effect of radiation: Autopsy-histologic investigations of bronchial carcinomas | DER EINFLUSS UNTERSCHIEDLICHER EINZELDOSEN UND FRAKTIONSZAHLEN AUF DIE STRAHLENWIRKUNG. AUTOPTISCH-HISTOLOGISCHE UNTERSUCHUNGEN AM BRONCHIALKARZINOM Strahlentherapie. 158: 151-155. PMID 7071877  1
1974 Huettner J, Eichhorn HJ, Dalluege KH. The role of mammography in the therapy of cancer of the breast | DIE AUFGABEN DER MAMMOGRAPHIE IM RAHMEN DER THERAPIE DES MAMMAKARZINOMS Deutsche Gesundheitswesen. 29: 1414-1420.  1
1968 Robertson JS, Moeller G. Compuation of continuous decompression schedules for deep sea dives. BNL-50104 T[Echnical Report]. Brookhaven National Laboratory. 1-37. PMID 5305460  0.48
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