Alan Cowan - Publications

Temple University, Philadelphia, PA, United States 
Pharmacology, Neuroscience Biology

44 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Inan S, Huerta AT, Jensen LE, Dun NJ, Cowan A. Nalbuphine, a kappa opioid receptor agonist and mu opioid receptor antagonist attenuates pruritus, decreases IL-31, and increases IL-10 in mice with contact dermatitis. European Journal of Pharmacology. 172702. PMID 31568781 DOI: 10.1016/j.ejphar.2019.172702  0.36
2019 Chen X, Cowan A, Inan S, Geller EB, Meissler JJ, Rawls SM, Tallarida RJ, Tallarida CS, Watson MN, Adler MW, Eisenstein TK. Opioid-Sparing Effects of Cannabinoids on Morphine Analgesia: Participation of CB1 and CB2 Receptors. British Journal of Pharmacology. PMID 31218677 DOI: 10.1111/bph.14769  0.64
2019 Inan S, Watson MN, Doura M, Tallarida CS, Meissler JJ, Chen X, Geller EB, Cowan A, Rawls SM, Eisenstein TK, Adler MW. Chemokine receptor antagonists enhance the antinociceptive activity of oxycodone and meperidine on incisional pain in rats. British Journal of Anaesthesia. PMID 30916010 DOI: 10.1016/j.bja.2019.01.021  0.64
2018 Inan S, Eisenstein TK, Watson MN, Doura M, Meissler JJ, Tallarida CS, Chen X, Geller EB, Rawls SM, Cowan A, Adler MW. Co-Administration of Chemokine Receptor Antagonists with Morphine Potentiates Morphine's Analgesic Effect on Incisional Pain in Rats. The Journal of Pharmacology and Experimental Therapeutics. PMID 30249618 DOI: 10.1124/jpet.118.252890  0.64
2018 Liu JJ, Chiu YT, DiMattio KM, Chen C, Huang P, Gentile TA, Muschamp JW, Cowan A, Mann M, Liu-Chen LY. Phosphoproteomic approach for agonist-specific signaling in mouse brains: mTOR pathway is involved in κ opioid aversion. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 30082888 DOI: 10.1038/s41386-018-0155-0  0.32
2018 Lyu RM, Cowan A, Zhang Y, Chen YH, Dun SL, Chang JK, Dun NJ, Luo JJ. Phoenixin: a novel brain-gut-skin peptide with multiple bioactivity. Acta Pharmacologica Sinica. PMID 29542680 DOI: 10.1038/aps.2017.195  0.32
2016 Cowan A, Sarabia-Estrada R, Wilkerson G, McKnight P, Guarnieri M. Lack of adverse effects during a target animal safety trial of extended-release buprenorphine in Fischer 344 rats. Lab Animal. 45: 28-34. PMID 26684956 DOI: 10.1038/laban.745  0.64
2015 Qu H, Costache MC, Inan S, Cowan A, Devore D, Ducheyne P. Local, Controlled Delivery of Local Anesthetics In Vivo from Polymer - Xerogel Composites. Pharmaceutical Research. PMID 26555665 DOI: 10.1007/s11095-015-1822-z  0.36
2015 Cowan A, Lyu RM, Chen YH, Dun SL, Chang JK, Dun NJ. Phoenixin: a candidate pruritogen in the mouse. Neuroscience. PMID 26415767 DOI: 10.1016/j.neuroscience.2015.09.055  0.32
2015 Cowan A, Kehner GB, Inan S. Targeting Itch with Ligands Selective for κ Opioid Receptors. Handbook of Experimental Pharmacology. 226: 291-314. PMID 25861786 DOI: 10.1007/978-3-662-44605-8_16  0.64
2015 Zhang Y, Dun SL, Chen YH, Luo JJ, Cowan A, Dun NJ. Scratching activates microglia in the mouse spinal cord. Journal of Neuroscience Research. 93: 466-74. PMID 25354468 DOI: 10.1002/jnr.23501  0.32
2011 Wang YJ, Rasakham K, Huang P, Chudnovskaya D, Cowan A, Liu-Chen LY. Sex difference in κ-opioid receptor (KOPR)-mediated behaviors, brain region KOPR level and KOPR-mediated guanosine 5'-O-(3-[35S]thiotriphosphate) binding in the guinea pig. The Journal of Pharmacology and Experimental Therapeutics. 339: 438-50. PMID 21841040 DOI: 10.1124/jpet.111.183905  0.64
2011 Palma J, Cowan A, Geller EB, Adler MW, Benamar K. Differential antinociceptive effects of buprenorphine and methadone in the presence of HIV-gp120. Drug and Alcohol Dependence. 118: 497-9. PMID 21600706 DOI: 10.1016/j.drugalcdep.2011.04.010  0.64
2011 Kim J, Cowan A, Lisek R, Raymondi N, Rosenthal A, Hirsch DD, Rawls SM. Icilin-evoked behavioral stimulation is attenuated by alphaâ‚‚-adrenoceptor activation. Brain Research. 1384: 110-7. PMID 21315691 DOI: 10.1016/j.brainres.2011.02.002  0.64
2011 Inan S, Dun NJ, Cowan A. Investigation of gastrin-releasing peptide as a mediator for 5'-guanidinonaltrindole-induced compulsive scratching in mice. Peptides. 32: 286-92. PMID 21126550 DOI: 10.1016/j.peptides.2010.11.022  0.64
2011 Benamar K, Palma J, Cowan A, Geller EB, Adler MW. Analgesic efficacy of buprenorphine in the presence of high levels of SDF-1α/CXCL12 in the brain. Drug and Alcohol Dependence. 114: 246-8. PMID 21112161 DOI: 10.1016/j.drugalcdep.2010.08.015  0.64
2010 Zhao P, Sharir H, Kapur A, Cowan A, Geller EB, Adler MW, Seltzman HH, Reggio PH, Heynen-Genel S, Sauer M, Chung TD, Bai Y, Chen W, Caron MG, Barak LS, et al. Targeting of the orphan receptor GPR35 by pamoic acid: a potent activator of extracellular signal-regulated kinase and β-arrestin2 with antinociceptive activity. Molecular Pharmacology. 78: 560-8. PMID 20826425 DOI: 10.1124/mol.110.066746  0.64
2009 Huang P, Liu-Chen LY, Unterwald EM, Cowan A. Hyperlocomotion and paw tremors are two highly quantifiable signs of SR141716-precipitated withdrawal from delta9-tetrahydrocannabinol in C57BL/6 mice. Neuroscience Letters. 465: 66-70. PMID 19733208 DOI: 10.1016/j.neulet.2009.08.073  0.64
2009 Inan S, Dun NJ, Cowan A. Inhibitory effect of lidocaine on pain and itch using formalin-induced nociception and 5'-guanidinonaltrindole-induced scratching models in mice: behavioral and neuroanatomical evidence. European Journal of Pharmacology. 616: 141-6. PMID 19549515 DOI: 10.1016/j.ejphar.2009.06.026  0.64
2009 Werkheiser J, Cowan A, Gomez T, Henry C, Parekh S, Chau S, Baron DA, Rawls SM. Icilin-induced wet-dog shakes in rats are dependent on NMDA receptor activation and nitric oxide production. Pharmacology, Biochemistry, and Behavior. 92: 543-8. PMID 19248800 DOI: 10.1016/j.pbb.2009.02.005  0.64
2008 Ding Z, Cowan A, Rawls SM. 5-HT reuptake and 5-HT2 receptors modulate capsaicin-evoked hypothermia in rats. Neuroscience Letters. 430: 191-6. PMID 18155835 DOI: 10.1016/j.neulet.2007.10.033  0.64
2008 Wang Y, Chen Y, Xu W, Lee DY, Ma Z, Rawls SM, Cowan A, Liu-Chen LY. 2-Methoxymethyl-salvinorin B is a potent kappa opioid receptor agonist with longer lasting action in vivo than salvinorin A. The Journal of Pharmacology and Experimental Therapeutics. 324: 1073-83. PMID 18089845 DOI: 10.1124/jpet.107.132142  0.64
2008 Ding Z, Gomez T, Werkheiser JL, Cowan A, Rawls SM. Icilin induces a hyperthermia in rats that is dependent on nitric oxide production and NMDA receptor activation. European Journal of Pharmacology. 578: 201-8. PMID 17976579 DOI: 10.1016/j.ejphar.2007.09.030  0.64
2007 Werkheiser JL, Rawls SM, Cowan A. Nalfurafine, the kappa opioid agonist, inhibits icilin-induced wet-dog shakes in rats and antagonizes glutamate release in the dorsal striatum. Neuropharmacology. 52: 925-30. PMID 17150231 DOI: 10.1016/j.neuropharm.2006.10.010  0.64
2006 Ding Z, Cowan A, Tallarida R, Rawls SM. Capsaicin and nitric oxide synthase inhibitor interact to evoke a hypothermic synergy. Neuroscience Letters. 409: 41-6. PMID 17018247 DOI: 10.1016/j.neulet.2006.09.018  0.64
2006 Werkheiser JL, Rawls SM, Cowan A. Mu and kappa opioid receptor agonists antagonize icilin-induced wet-dog shaking in rats. European Journal of Pharmacology. 547: 101-5. PMID 16945367 DOI: 10.1016/j.ejphar.2006.07.026  0.64
2006 Inan S, Cowan A. Nalfurafine, a kappa opioid receptor agonist, inhibits scratching behavior secondary to cholestasis induced by chronic ethynylestradiol injections in rats. Pharmacology, Biochemistry, and Behavior. 85: 39-43. PMID 16919318 DOI: 10.1016/j.pbb.2006.07.004  0.64
2006 Rawls SM, Ding Z, Cowan A. Role of TRPV1 and cannabinoid CB1 receptors in AM 404-evoked hypothermia in rats. Pharmacology, Biochemistry, and Behavior. 83: 508-16. PMID 16647109 DOI: 10.1016/j.pbb.2006.03.011  0.64
2006 Werkheiser JL, Rawls SM, Cowan A. Icilin evokes a dose- and time-dependent increase in glutamate within the dorsal striatum of rats. Amino Acids. 30: 307-9. PMID 16622598 DOI: 10.1007/s00726-005-0306-6  0.64
2006 Rawls SM, Allebach C, Cowan A. Nitric oxide synthase mediates delta opioid receptor-induced hypothermia in rats. European Journal of Pharmacology. 536: 109-12. PMID 16566919 DOI: 10.1016/j.ejphar.2006.02.044  0.64
2006 Feng P, Rahim RT, Cowan A, Liu-Chen LY, Peng X, Gaughan J, Meissler JJ, Adler MW, Eisenstein TK. Effects of mu, kappa or delta opioids administered by pellet or pump on oral Salmonella infection and gastrointestinal transit. European Journal of Pharmacology. 534: 250-7. PMID 16513108 DOI: 10.1016/j.ejphar.2006.01.048  0.64
2006 Rawls SM, Cowan A. Modulation of delta opioid-evoked hypothermia in rats by WAY 100635 and fluoxetine. Neuroscience Letters. 398: 319-24. PMID 16483716 DOI: 10.1016/j.neulet.2006.01.017  0.64
2005 Ding Z, Cowan A, Rawls SM. Capsaicin evokes hypothermia independent of cannabinoid CB1 and CB2 receptors. Brain Research. 1065: 147-51. PMID 16309633 DOI: 10.1016/j.brainres.2005.10.026  0.64
2005 Inan S, Cowan A. Reduced kappa-opioid activity in a rat model of cholestasis. European Journal of Pharmacology. 518: 182-6. PMID 16054619 DOI: 10.1016/j.ejphar.2005.06.025  0.64
2005 Rawls SM, Hewson JM, Inan S, Cowan A. Brain delta2 opioid receptors mediate SNC-80-evoked hypothermia in rats. Brain Research. 1049: 61-9. PMID 15936000 DOI: 10.1016/j.brainres.2005.04.074  0.64
2005 Zhang N, Inan S, Inan S, Cowan A, Sun R, Wang JM, Rogers TJ, Caterina M, Oppenheim JJ. A proinflammatory chemokine, CCL3, sensitizes the heat- and capsaicin-gated ion channel TRPV1. Proceedings of the National Academy of Sciences of the United States of America. 102: 4536-41. PMID 15764707 DOI: 10.1073/pnas.0406030102  0.36
2005 Rawls SM, Ding Z, Gray AM, Cowan A. Peripheral kappa-opioid agonist, ICI 204448, evokes hypothermia in cold-exposed rats. Pharmacology. 74: 79-83. PMID 15687734 DOI: 10.1159/000083704  0.64
2005 Wang Y, Tang K, Inan S, Siebert D, Holzgrabe U, Lee DY, Huang P, Li JG, Cowan A, Liu-Chen LY. Comparison of pharmacological activities of three distinct kappa ligands (Salvinorin A, TRK-820 and 3FLB) on kappa opioid receptors in vitro and their antipruritic and antinociceptive activities in vivo. The Journal of Pharmacology and Experimental Therapeutics. 312: 220-30. PMID 15383632 DOI: 10.1124/jpet.104.073668  0.64
2004 Inan S, Cowan A. Kappa opioid agonists suppress chloroquine-induced scratching in mice. European Journal of Pharmacology. 502: 233-7. PMID 15476749 DOI: 10.1016/j.ejphar.2004.09.010  0.64
2003 Rawls SM, Adler MW, Gaughan JP, Baron A, Geller EB, Cowan A. NMDA receptors modulate morphine-induced hyperthermia. Brain Research. 984: 76-83. PMID 12932841 DOI: 10.1016/S0006-8993(03)03093-2  0.64
2002 De Haven-Hudkins DL, Cowan A, Cortes Burgos L, Daubert JD, Cassel JA, DeHaven RN, Kehner GB, Kumar V. Antipruritic and antihyperalgesic actions of loperamide and analogs Life Sciences. 71: 2787-2796. PMID 12383884 DOI: 10.1016/S0024-3205(02)02102-1  0.64
2002 Rahim RT, Adler MW, Meissler JJ, Cowan A, Rogers TJ, Geller EB, Eisenstein TK. Abrupt or precipitated withdrawal from morphine induces immunosuppression. Journal of Neuroimmunology. 127: 88-95. PMID 12044979 DOI: 10.1016/S0165-5728(02)00103-0  0.64
2002 Gopal S, Tzeng TB, Cowan A. Characterization of the pharmacokinetics of buprenorphine and norbuprenorphine in rats after intravenous bolus administration of buprenorphine. European Journal of Pharmaceutical Sciences : Official Journal of the European Federation For Pharmaceutical Sciences. 15: 287-93. PMID 11923061 DOI: 10.1016/S0928-0987(02)00009-X  0.64
2001 Huang P, Kehner GB, Cowan A, Liu-Chen LY. Comparison of pharmacological activities of buprenorphine and norbuprenorphine: norbuprenorphine is a potent opioid agonist. The Journal of Pharmacology and Experimental Therapeutics. 297: 688-95. PMID 11303059  0.64
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