Eliot L. Gardner - Publications

Affiliations: 
Yeshiva University, New York, NY, United States 
Area:
Neuroscience Biology, Behavioral Psychology, Psychobiology Psychology

147 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Spiller KJ, Bi GH, He Y, Galaj E, Gardner EL, Xi ZX. Cannabinoid CB and CB receptor mechanisms underlie cannabis reward and aversion in rats. British Journal of Pharmacology. PMID 30767215 DOI: 10.1111/bph.14625  0.32
2018 You ZB, Bi GH, Galaj E, Kumar V, Cao J, Gadiano A, Rais R, Slusher BS, Gardner EL, Xi ZX, Newman AH. Dopamine DR antagonist VK4-116 attenuates oxycodone self-administration and reinstatement without compromising its antinociceptive effects. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 30555159 DOI: 10.1038/s41386-018-0284-5  0.32
2018 Gao JT, Jordan C, Bi GH, He Y, Yang HJ, Gardner EL, Xi ZX. Deletion of the type 2 metabotropic glutamate receptor increases heroin abuse vulnerability in transgenic rats. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 30283001 DOI: 10.1038/s41386-018-0231-5  0.32
2018 Zhan J, Jordan CJ, Bi GH, He XH, Gardner EL, Wang YL, Xi ZX. Genetic deletion of the dopamine D3 receptor increases vulnerability to heroin in mice. Neuropharmacology. PMID 30138692 DOI: 10.1016/j.neuropharm.2018.08.016  0.32
2018 Zhang HY, Shen H, Jordan CJ, Liu QR, Gardner EL, Bonci A, Xi ZX. CB receptor antibody signal specificity: correlations with the use of partial CB-knockout mice and anti-rat CB receptor antibodies. Acta Pharmacologica Sinica. PMID 29967455 DOI: 10.1038/s41401-018-0037-3  0.32
2018 He XH, Jordan CJ, Vemuri K, Bi GH, Zhan J, Gardner EL, Makriyannis A, Wang YL, Xi ZX. Cannabinoid CB receptor neutral antagonist AM4113 inhibits heroin self-administration without depressive side effects in rats. Acta Pharmacologica Sinica. PMID 29967454 DOI: 10.1038/s41401-018-0059-x  0.32
2018 Li X, Peng XQ, Jordan CJ, Li J, Bi GH, He Y, Yang HJ, Zhang HY, Gardner EL, Xi ZX. mGluR5 antagonism inhibits cocaine reinforcement and relapse by elevation of extracellular glutamate in the nucleus accumbens via a CB1 receptor mechanism. Scientific Reports. 8: 3686. PMID 29487381 DOI: 10.1038/s41598-018-22087-1  0.32
2017 Liu QR, Canseco-Alba A, Zhang HY, Tagliaferro P, Chung M, Dennis E, Sanabria B, Schanz N, Escosteguy-Neto JC, Ishiguro H, Lin Z, Sgro S, Leonard CM, Santos-Junior JG, Gardner EL, et al. Cannabinoid type 2 receptors in dopamine neurons inhibits psychomotor behaviors, alters anxiety, depression and alcohol preference. Scientific Reports. 7: 17410. PMID 29234141 DOI: 10.1038/s41598-017-17796-y  0.32
2017 Han X, He Y, Bi GH, Zhang HY, Song R, Liu QR, Egan JM, Gardner EL, Li J, Xi ZX. CB1 Receptor Activation on VgluT2-Expressing Glutamatergic Neurons Underlies Δ(9)-Tetrahydrocannabinol (Δ(9)-THC)-Induced Aversive Effects in Mice. Scientific Reports. 7: 12315. PMID 28951549 DOI: 10.1038/s41598-017-12399-z  0.32
2017 You ZB, Gao JT, Bi GH, He Y, Boateng C, Cao J, Gardner EL, Newman AH, Xi ZX. The novel dopamine D3 receptor antagonists/partial agonists CAB2-015 and BAK4-54 inhibit oxycodone-taking and oxycodone-seeking behavior in rats. Neuropharmacology. PMID 28888944 DOI: 10.1016/j.neuropharm.2017.09.007  0.32
2017 Zhang HY, Bi GH, Yang HJ, He Y, Xue G, Cao JJ, Tanda G, Gardner EL, Newman AH, Xi ZX. The Novel Modafinil Analog, JJC8-016, as a Potential Cocaine Abuse Pharmacotherapeutic. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 28266501 DOI: 10.1038/npp.2017.41  0.32
2016 Xi ZX, Song R, Li X, Lu GY, Peng XQ, He Y, Bi GH, Shen P, Yang HJ, Zhang H, Li J, Froimowitz M, Gardner EL. CTDP-32,476: A Promising Agonist Therapy for Treatment of Cocaine Addiction. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 27534265 DOI: 10.1038/npp.2016.155  1
2016 Zhang HY, Gao M, Shen H, Bi GH, Yang HJ, Liu QR, Wu J, Gardner EL, Bonci A, Xi ZX. Expression of functional cannabinoid CB2 receptor in VTA dopamine neurons in rats. Addiction Biology. PMID 26833913 DOI: 10.1111/adb.12367  0.32
2015 Wang XF, Bi GH, He Y, Yang HJ, Gao JT, Okunola-Bakare OM, Slack RD, Gardner EL, Xi ZX, Newman AH. R-modafinil attenuates nicotine-taking and nicotine-seeking behavior in alcohol-preferring rats. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 40: 1762-71. PMID 25613829 DOI: 10.1038/npp.2015.24  0.32
2015 Zhang HY, Bi GH, Li X, Li J, Qu H, Zhang SJ, Li CY, Onaivi ES, Gardner EL, Xi ZX, Liu QR. Species differences in cannabinoid receptor 2 and receptor responses to cocaine self-administration in mice and rats. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 40: 1037-51. PMID 25374096 DOI: 10.1038/npp.2014.297  0.32
2014 Zhang HY, Gao M, Liu QR, Bi GH, Li X, Yang HJ, Gardner EL, Wu J, Xi ZX. Cannabinoid CB2 receptors modulate midbrain dopamine neuronal activity and dopamine-related behavior in mice. Proceedings of the National Academy of Sciences of the United States of America. 111: E5007-15. PMID 25368177 DOI: 10.1073/pnas.1413210111  1
2014 Song R, Bi GH, Zhang HY, Yang RF, Gardner EL, Li J, Xi ZX. Blockade of D3 receptors by YQA14 inhibits cocaine's rewarding effects and relapse to drug-seeking behavior in rats. Neuropharmacology. 77: 398-405. PMID 24176392 DOI: 10.1016/j.neuropharm.2013.10.010  1
2014 Keck TM, Zou MF, Bi GH, Zhang HY, Wang XF, Yang HJ, Srivastava R, Gardner EL, Xi ZX, Newman AH. A novel mGluR5 antagonist, MFZ 10-7, inhibits cocaine-taking and cocaine-seeking behavior in rats. Addiction Biology. 19: 195-209. PMID 24001208 DOI: 10.1111/adb.12086  1
2013 Song R, Zhang HY, Peng XQ, Su RB, Yang RF, Li J, Xi ZX, Gardner EL. Dopamine D(3) receptor deletion or blockade attenuates cocaine-induced conditioned place preference in mice. Neuropharmacology. 72: 82-7. PMID 23643749 DOI: 10.1016/j.neuropharm.2013.04.042  1
2013 Keck TM, Yang HJ, Bi GH, Huang Y, Zhang HY, Srivastava R, Gardner EL, Newman AH, Xi ZX. Fenobam sulfate inhibits cocaine-taking and cocaine-seeking behavior in rats: implications for addiction treatment in humans. Psychopharmacology. 229: 253-65. PMID 23615919 DOI: 10.1007/s00213-013-3106-9  1
2013 Rice OV, Heidbreder CA, Gardner EL, Schonhar CD, Ashby CR. The selective D₃ receptor antagonist SB-277011A attenuates morphine-triggered reactivation of expression of cocaine-induced conditioned place preference. Synapse (New York, N.Y.). 67: 469-75. PMID 23404528 DOI: 10.1002/syn.21653  1
2013 Xi ZX, Li X, Li J, Peng XQ, Song R, Gaál J, Gardner EL. Blockade of dopamine D3 receptors in the nucleus accumbens and central amygdala inhibits incubation of cocaine craving in rats. Addiction Biology. 18: 665-77. PMID 22913325 DOI: 10.1111/j.1369-1600.2012.00486.x  1
2012 Song R, Zhang HY, Li X, Bi GH, Gardner EL, Xi ZX. Increased vulnerability to cocaine in mice lacking dopamine D3 receptors. Proceedings of the National Academy of Sciences of the United States of America. 109: 17675-80. PMID 23045656 DOI: 10.1073/pnas.1205297109  1
2012 Srivastava R, Xi ZX, Gardner EL. Cocaine-taking and cocaine-seeking behaviors in rats remain stable after systemic administration of GYKI 52466: a non-competitive AMPA receptor antagonist. Neuroscience Letters. 508: 106-9. PMID 22206835 DOI: 10.1016/j.neulet.2011.12.028  1
2012 Rice OV, Gardner EL, Heidbreder CA, Ashby CR. The acute administration of the selective dopamine D(3) receptor antagonist SB-277011A reverses conditioned place aversion produced by naloxone precipitated withdrawal from acute morphine administration in rats. Synapse (New York, N.Y.). 66: 85-7. PMID 21905128 DOI: 10.1002/syn.20983  1
2012 Song R, Yang RF, Wu N, Su RB, Li J, Peng XQ, Li X, Gaál J, Xi ZX, Gardner EL. YQA14: a novel dopamine D3 receptor antagonist that inhibits cocaine self-administration in rats and mice, but not in D3 receptor-knockout mice. Addiction Biology. 17: 259-73. PMID 21507153 DOI: 10.1111/j.1369-1600.2011.00317.x  1
2011 Xi ZX, Peng XQ, Li X, Song R, Zhang HY, Liu QR, Yang HJ, Bi GH, Li J, Gardner EL. Brain cannabinoid CB₂ receptors modulate cocaine's actions in mice. Nature Neuroscience. 14: 1160-6. PMID 21785434 DOI: 10.1038/nn.2874  1
2011 Gardner EL. Addiction and brain reward and antireward pathways. Advances in Psychosomatic Medicine. 30: 22-60. PMID 21508625 DOI: 10.1159/000324065  1
2011 Higley AE, Kiefer SW, Li X, Gaál J, Xi ZX, Gardner EL. Dopamine D(3) receptor antagonist SB-277011A inhibits methamphetamine self-administration and methamphetamine-induced reinstatement of drug-seeking in rats. European Journal of Pharmacology. 659: 187-92. PMID 21466803 DOI: 10.1016/j.ejphar.2011.02.046  1
2011 Higley AE, Spiller K, Grundt P, Newman AH, Kiefer SW, Xi ZX, Gardner EL. PG01037, a novel dopamine D3 receptor antagonist, inhibits the effects of methamphetamine in rats. Journal of Psychopharmacology (Oxford, England). 25: 263-73. PMID 20142301 DOI: 10.1177/0269881109358201  1
2010 Peng XQ, Xi ZX, Li X, Spiller K, Li J, Chun L, Wu KM, Froimowitz M, Gardner EL. Is slow-onset long-acting monoamine transport blockade to cocaine as methadone is to heroin? Implication for anti-addiction medications. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 35: 2564-78. PMID 20827272 DOI: 10.1038/npp.2010.133  1
2010 Li X, Li J, Gardner EL, Xi ZX. Activation of mGluR7s inhibits cocaine-induced reinstatement of drug-seeking behavior by a nucleus accumbens glutamate-mGluR2/3 mechanism in rats. Journal of Neurochemistry. 114: 1368-80. PMID 20534005 DOI: 10.1111/j.1471-4159.2010.06851.x  1
2010 Peng XQ, Gardner EL, Xi ZX. Gamma-vinyl GABA increases nonvesicular release of GABA and glutamate in the nucleus accumbens in rats via action on anion channels and GABA transporters. Psychopharmacology. 208: 511-9. PMID 20033132 DOI: 10.1007/s00213-009-1753-7  1
2010 Xi ZX, Li X, Peng XQ, Li J, Chun L, Gardner EL, Thomas AG, Slusher BS, Ashby CR. Inhibition of NAALADase by 2-PMPA attenuates cocaine-induced relapse in rats: a NAAG-mGluR2/3-mediated mechanism. Journal of Neurochemistry. 112: 564-76. PMID 19895667 DOI: 10.1111/j.1471-4159.2009.06478.x  1
2010 Peng XQ, Li J, Gardner EL, Ashby CR, Thomas A, Wozniak K, Slusher BS, Xi ZX. Oral administration of the NAALADase inhibitor GPI-5693 attenuates cocaine-induced reinstatement of drug-seeking behavior in rats. European Journal of Pharmacology. 627: 156-61. PMID 19887067 DOI: 10.1016/j.ejphar.2009.10.062  1
2010 Xi ZX, Kiyatkin M, Li X, Peng XQ, Wiggins A, Spiller K, Li J, Gardner EL. N-acetylaspartylglutamate (NAAG) inhibits intravenous cocaine self-administration and cocaine-enhanced brain-stimulation reward in rats. Neuropharmacology. 58: 304-13. PMID 19559037 DOI: 10.1016/j.neuropharm.2009.06.016  1
2009 Xi ZX, Spiller K, Gardner EL. Mechanism-based medication development for the treatment of nicotine dependence. Acta Pharmacologica Sinica. 30: 723-39. PMID 19434058 DOI: 10.1038/aps.2009.46  1
2009 Spiller K, Xi ZX, Li X, Ashby CR, Callahan PM, Tehim A, Gardner EL. Varenicline attenuates nicotine-enhanced brain-stimulation reward by activation of alpha4beta2 nicotinic receptors in rats. Neuropharmacology. 57: 60-6. PMID 19393252 DOI: 10.1016/j.neuropharm.2009.04.006  1
2009 Xi ZX, Kleitz HK, Deng X, Ladenheim B, Peng XQ, Li X, Gardner EL, Stein EA, Cadet JL. A single high dose of methamphetamine increases cocaine self-administration by depletion of striatal dopamine in rats. Neuroscience. 161: 392-402. PMID 19336247 DOI: 10.1016/j.neuroscience.2009.03.060  1
2009 Li X, Li J, Peng XQ, Spiller K, Gardner EL, Xi ZX. Metabotropic glutamate receptor 7 modulates the rewarding effects of cocaine in rats: involvement of a ventral pallidal GABAergic mechanism. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 34: 1783-96. PMID 19158667 DOI: 10.1038/npp.2008.236  1
2009 Peng XQ, Ashby CR, Spiller K, Li X, Li J, Thomasson N, Millan MJ, Mocaër E, MuÅ„oz C, Gardner EL, Xi ZX. The preferential dopamine D3 receptor antagonist S33138 inhibits cocaine reward and cocaine-triggered relapse to drug-seeking behavior in rats. Neuropharmacology. 56: 752-60. PMID 19136017 DOI: 10.1016/j.neuropharm.2008.12.007  1
2009 Li X, Hoffman AF, Peng XQ, Lupica CR, Gardner EL, Xi ZX. Attenuation of basal and cocaine-enhanced locomotion and nucleus accumbens dopamine in cannabinoid CB1-receptor-knockout mice. Psychopharmacology. 204: 1-11. PMID 19099297 DOI: 10.1007/s00213-008-1432-0  1
2008 Xi ZX, Gardner EL. Hypothesis-driven medication discovery for the treatment of psychostimulant addiction. Current Drug Abuse Reviews. 1: 303-27. PMID 19430578  1
2008 Gardner EL. Use of animal models to develop antiaddiction medications. Current Psychiatry Reports. 10: 377-84. PMID 18803910 DOI: 10.1007/s11920-008-0061-y  1
2008 Thanos PK, Michaelides M, Ho CW, Wang GJ, Newman AH, Heidbreder CA, Ashby CR, Gardner EL, Volkow ND. The effects of two highly selective dopamine D3 receptor antagonists (SB-277011A and NGB-2904) on food self-administration in a rodent model of obesity. Pharmacology, Biochemistry, and Behavior. 89: 499-507. PMID 18329700 DOI: 10.1016/j.pbb.2008.02.003  1
2008 Li X, Gardner EL, Xi ZX. The metabotropic glutamate receptor 7 (mGluR7) allosteric agonist AMN082 modulates nucleus accumbens GABA and glutamate, but not dopamine, in rats. Neuropharmacology. 54: 542-51. PMID 18155073 DOI: 10.1016/j.neuropharm.2007.11.005  1
2008 Peng XQ, Li X, Li J, Ramachandran PV, Gagare PD, Pratihar D, Ashby CR, Gardner EL, Xi ZX. Effects of gabapentin on cocaine self-administration, cocaine-triggered relapse and cocaine-enhanced nucleus accumbens dopamine in rats. Drug and Alcohol Dependence. 97: 207-15. PMID 18065162 DOI: 10.1016/j.drugalcdep.2007.09.019  1
2008 Peng XQ, Li X, Gilbert JG, Pak AC, Ashby CR, Brodie JD, Dewey SL, Gardner EL, Xi ZX. Gamma-vinyl GABA inhibits cocaine-triggered reinstatement of drug-seeking behavior in rats by a non-dopaminergic mechanism. Drug and Alcohol Dependence. 97: 216-25. PMID 18063319 DOI: 10.1016/j.drugalcdep.2007.10.004  1
2008 Spiller K, Xi ZX, Peng XQ, Newman AH, Ashby CR, Heidbreder C, Gaál J, Gardner EL. The selective dopamine D3 receptor antagonists SB-277011A and NGB 2904 and the putative partial D3 receptor agonist BP-897 attenuate methamphetamine-enhanced brain stimulation reward in rats. Psychopharmacology. 196: 533-42. PMID 17985117 DOI: 10.1007/s00213-007-0986-6  1
2008 Xi ZX, Spiller K, Pak AC, Gilbert J, Dillon C, Li X, Peng XQ, Gardner EL. Cannabinoid CB1 receptor antagonists attenuate cocaine's rewarding effects: experiments with self-administration and brain-stimulation reward in rats. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 33: 1735-45. PMID 17728698 DOI: 10.1038/sj.npp.1301552  1
2007 Xi ZX, Yang Z, Li SJ, Li X, Dillon C, Peng XQ, Spiller K, Gardner EL. Levo-tetrahydropalmatine inhibits cocaine's rewarding effects: experiments with self-administration and brain-stimulation reward in rats. Neuropharmacology. 53: 771-82. PMID 17888459 DOI: 10.1016/j.neuropharm.2007.08.004  1
2007 Xi ZX, Gardner EL. Pharmacological actions of NGB 2904, a selective dopamine D3 receptor antagonist, in animal models of drug addiction. Cns Drug Reviews. 13: 240-59. PMID 17627675 DOI: 10.1111/j.1527-3458.2007.00013.x  1
2007 Heidbreder CA, Andreoli M, Marcon C, Hutcheson DM, Gardner EL, Ashby CR. Evidence for the role of dopamine D3 receptors in oral operant alcohol self-administration and reinstatement of alcohol-seeking behavior in mice. Addiction Biology. 12: 35-50. PMID 17407496 DOI: 10.1111/j.1369-1600.2007.00051.x  1
2006 Pak AC, Ashby CR, Heidbreder CA, Pilla M, Gilbert J, Xi ZX, Gardner EL. The selective dopamine D3 receptor antagonist SB-277011A reduces nicotine-enhanced brain reward and nicotine-paired environmental cue functions. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 9: 585-602. PMID 16942635 DOI: 10.1017/S1461145706006560  1
2006 Xi ZX, Gilbert JG, Peng XQ, Pak AC, Li X, Gardner EL. Cannabinoid CB1 receptor antagonist AM251 inhibits cocaine-primed relapse in rats: role of glutamate in the nucleus accumbens. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 8531-6. PMID 16914679 DOI: 10.1523/JNEUROSCI.0726-06.2006  1
2006 Gardner EL, Liu X, Paredes W, Giordano A, Spector J, Lepore M, Wu KM, Froimowitz M. A slow-onset, long-duration indanamine monoamine reuptake inhibitor as a potential maintenance pharmacotherapy for psychostimulant abuse: effects in laboratory rat models relating to addiction. Neuropharmacology. 51: 993-1003. PMID 16901516 DOI: 10.1016/j.neuropharm.2006.06.009  1
2006 Xi ZX, Newman AH, Gilbert JG, Pak AC, Peng XQ, Ashby CR, Gitajn L, Gardner EL. The novel dopamine D3 receptor antagonist NGB 2904 inhibits cocaine's rewarding effects and cocaine-induced reinstatement of drug-seeking behavior in rats. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 31: 1393-405. PMID 16205781 DOI: 10.1038/sj.npp.1300912  1
2005 O'Brien CP, Gardner EL. Critical assessment of how to study addiction and its treatment: human and non-human animal models. Pharmacology & Therapeutics. 108: 18-58. PMID 16183393 DOI: 10.1016/j.pharmthera.2005.06.018  1
2005 Xi ZX, Gilbert JG, Pak AC, Ashby CR, Heidbreder CA, Gardner EL. Selective dopamine D3 receptor antagonism by SB-277011A attenuates cocaine reinforcement as assessed by progressive-ratio and variable-cost-variable-payoff fixed-ratio cocaine self-administration in rats. The European Journal of Neuroscience. 21: 3427-38. PMID 16026480 DOI: 10.1111/j.1460-9568.2005.04159.x  1
2005 Heidbreder CA, Gardner EL, Xi ZX, Thanos PK, Mugnaini M, Hagan JJ, Ashby CR. The role of central dopamine D3 receptors in drug addiction: a review of pharmacological evidence. Brain Research. Brain Research Reviews. 49: 77-105. PMID 15960988 DOI: 10.1016/j.brainresrev.2004.12.033  1
2005 Gardner EL. Endocannabinoid signaling system and brain reward: emphasis on dopamine. Pharmacology, Biochemistry, and Behavior. 81: 263-84. PMID 15936806 DOI: 10.1016/j.pbb.2005.01.032  1
2005 Thanos PK, Katana JM, Ashby CR, Michaelides M, Gardner EL, Heidbreder CA, Volkow ND. The selective dopamine D3 receptor antagonist SB-277011-A attenuates ethanol consumption in ethanol preferring (P) and non-preferring (NP) rats. Pharmacology, Biochemistry, and Behavior. 81: 190-7. PMID 15894078 DOI: 10.1016/j.pbb.2005.03.013  1
2005 Gilbert JG, Newman AH, Gardner EL, Ashby CR, Heidbreder CA, Pak AC, Peng XQ, Xi ZX. Acute administration of SB-277011A, NGB 2904, or BP 897 inhibits cocaine cue-induced reinstatement of drug-seeking behavior in rats: role of dopamine D3 receptors. Synapse (New York, N.Y.). 57: 17-28. PMID 15858839 DOI: 10.1002/syn.20152  1
2004 Hayes RJ, Gardner EL. The basolateral complex of the amygdala mediates the modulation of intracranial self-stimulation threshold by drug-associated cues. The European Journal of Neuroscience. 20: 273-80. PMID 15245499 DOI: 10.1111/j.1460-9568.2004.03463.x  1
2004 Gorelick DA, Gardner EL, Xi ZX. Agents in development for the management of cocaine abuse. Drugs. 64: 1547-73. PMID 15233592 DOI: 10.2165/00003495-200464140-00004  1
2004 Luo F, Xi ZX, Wu G, Liu C, Gardner EL, Li SJ. Attenuation of brain response to heroin correlates with the reinstatement of heroin-seeking in rats by fMRI. Neuroimage. 22: 1328-35. PMID 15219605 DOI: 10.1016/j.neuroimage.2004.03.017  1
2004 Heidbreder CA, Andreoli M, Marcon C, Thanos PK, Ashby CR, Gardner EL. Role of dopamine D3 receptors in the addictive properties of ethanol. Drugs of Today (Barcelona, Spain : 1998). 40: 355-65. PMID 15190388 DOI: 10.1358/dot.2004.40.4.820081  1
2004 Xi ZX, Gilbert J, Campos AC, Kline N, Ashby CR, Hagan JJ, Heidbreder CA, Gardner EL. Blockade of mesolimbic dopamine D3 receptors inhibits stress-induced reinstatement of cocaine-seeking in rats. Psychopharmacology. 176: 57-65. PMID 15083257 DOI: 10.1007/s00213-004-1858-y  1
2003 Ashby CR, Paul M, Gardner EL, Heidbreder CA, Hagan JJ. Acute administration of the selective D3 receptor antagonist SB-277011A blocks the acquisition and expression of the conditioned place preference response to heroin in male rats. Synapse (New York, N.Y.). 48: 154-6. PMID 12645041 DOI: 10.1002/syn.10188  1
2003 Hayes RJ, Vorel SR, Spector J, Liu X, Gardner EL. Electrical and chemical stimulation of the basolateral complex of the amygdala reinstates cocaine-seeking behavior in the rat. Psychopharmacology. 168: 75-83. PMID 12545331 DOI: 10.1007/s00213-002-1328-3  1
2003 Sharan N, Chong VZ, Nair VD, Mishra RK, Hayes RJ, Gardner EL. Cocaine treatment increases expression of a 40 kDa catecholamine-regulated protein in discrete brain regions. Synapse (New York, N.Y.). 47: 33-44. PMID 12422371 DOI: 10.1002/syn.10140  1
2002 Gardner EL. Addictive potential of cannabinoids: the underlying neurobiology. Chemistry and Physics of Lipids. 121: 267-90. PMID 12505706 DOI: 10.1016/S0009-3084(02)00162-7  1
2002 Vorel SR, Ashby CR, Paul M, Liu X, Hayes R, Hagan JJ, Middlemiss DN, Stemp G, Gardner EL. Dopamine D3 receptor antagonism inhibits cocaine-seeking and cocaine-enhanced brain reward in rats. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 9595-603. PMID 12417684  1
2002 Gardner EL, Schiffer WK, Horan BA, Highfield D, Dewey SL, Brodie JD, Ashby CR. Gamma-vinyl GABA, an irreversible inhibitor of GABA transaminase, alters the acquisition and expression of cocaine-induced sensitization in male rats. Synapse (New York, N.Y.). 46: 240-50. PMID 12373739 DOI: 10.1002/syn.10138  1
2002 Turman JE, Lee OK, Chandler SH. Differential NR2A and NR2B expression between trigeminal neurons during early postnatal development. Synapse (New York, N.Y.). 44: 76-85. PMID 11891879 DOI: 10.1002/syn.10059  1
2001 Horan B, Gardner EL, Dewey SL, Brodie JD, Ashby CR. The selective σ1 receptor agonist, 1-(3,4-dimethoxyphenethyl)-4-(phenylpropyl)piperazine (SA4503), blocks the acquisition of the conditioned place preference response to (-)-nicotine in rats European Journal of Pharmacology. 426. PMID 11525784 DOI: 10.1016/S0014-2999(01)01229-8  1
2001 Paul M, Dewey SL, Gardner EL, Brodie JD, Ashby CR. Gamma-vinyl GABA (GVG) blocks expression of the conditioned place preference response to heroin in rats Synapse. 41: 219-220. PMID 11391783 DOI: 10.1002/syn.1078  1
2001 Vorel SR, Liu X, Hayes RJ, Spector JA, Gardner EL. Relapse to cocaine-seeking after hippocampal theta burst stimulation. Science (New York, N.Y.). 292: 1175-8. PMID 11349151 DOI: 10.1126/science.1058043  1
2001 Gerasimov MR, Schiffer WK, Gardner EL, Marsteller DA, Lennon IC, Taylor SJ, Brodie JD, Ashby CR, Dewey SL. GABAergic blockade of cocaine-associated cue-induced increases in nucleus accumbens dopamine. European Journal of Pharmacology. 414: 205-9. PMID 11239920 DOI: 10.1016/S0014-2999(01)00800-7  1
2000 Gardner EL. What we have learned about addiction from animal models of drug self-administration American Journal On Addictions. 9: 285-313. PMID 11155784 DOI: 10.1080/105504900750047355  1
2000 Froimowitz M, Wu KM, Moussa A, Haidar RM, Jurayj J, George C, Gardner EL. Slow-onset, long-duration 3-(3′,4′-dichlorophenyl)-1-indanamine monoamine reuptake blockers as potential medications to treat cocaine abuse Journal of Medicinal Chemistry. 43: 4981-4992. PMID 11150168 DOI: 10.1021/jm000201d  1
2000 Gardner EL, Ashby CR. Heterogeneity of the mesotelencephalic dopamine fibers: Physiology and pharmacology Neuroscience and Biobehavioral Reviews. 24: 115-118. PMID 10654666 DOI: 10.1016/S0149-7634(99)00048-2  1
2000 Horan B, Gardner EL, Ashby CR. Enhancement of conditioned place preference response to cocaine in rats following subchronic administration of 3,4-methylenedioxymethamphetamine (MDMA) Synapse. 35: 160-162. PMID 10611642 DOI: 10.1002/(SICI)1098-2396(200002)35:2<160::AID-SYN9>3.0.CO;2-O  1
1999 Gerasimov MR, Ashby CR, Gardner EL, Mills MJ, Brodie JD, Dewey SL. Gamma-vinyl GABA inhibits methamphetamine, heroin, or ethanol-induced increases in nucleus accumbens dopamine. Synapse (New York, N.Y.). 34: 11-9. PMID 10459167 DOI: 10.1002/(SICI)1098-2396(199910)34:1<11::AID-SYN2>3.0.CO;2-5  1
1999 Dewey SL, Brodie JD, Gerasimov M, Horan B, Gardner EL, Ashby CR. A pharmacologic strategy for the treatment of nicotine addiction Synapse. 31: 76-86. PMID 10025686 DOI: 10.1002/(SICI)1098-2396(199901)31:1<76::AID-SYN10>3.0.CO;2-Y  1
1998 Gardner EL, Vorel SR. Cannabinoid transmission and reward-related events. Neurobiology of Disease. 5: 502-33. PMID 9974181 DOI: 10.1006/nbdi.1998.0219  1
1998 Dewey SL, Morgan AE, Ashby CR, Horan B, Kushner SA, Logan J, Volkow ND, Fowler JS, Gardner EL, Brodie JD. A novel strategy for the treatment of cocaine addiction. Synapse (New York, N.Y.). 30: 119-29. PMID 9723781 DOI: 10.1002/(SICI)1098-2396(199810)30:2<119::AID-SYN1>3.0.CO;2-F  1
1998 Minabe Y, Gardner EL, Ashby CR. Differential effects of chronic haloperidol administration on midbrain dopamine neurons in Sprague-Dawley, fischer 344, and lewis rats: An in vivo electrophysiological study Synapse. 29: 269-271. PMID 9635897 DOI: 10.1002/(SICI)1098-2396(199807)29:3<269::AID-SYN9>3.0.CO;2-4  1
1997 Gifford AN, Gardner EL, Ashby CR. The effect of intravenous administration of delta-9-tetrahydrocannabinol on the activity of A10 dopamine neurons recorded in vivo in anesthetized rats Neuropsychobiology. 36: 96-99. PMID 9267859  1
1997 Horan B, Smith M, Gardner EL, Lepore M, Ashby CR. (-)-Nicotine produces conditioned place preference in Lewis, but not Fischer 344 rats Synapse. 26: 93-94. PMID 9097409 DOI: 10.1002/(SICI)1098-2396(199705)26:1<93::AID-SYN10>3.0.CO;2-W  1
1996 Lepore M, Liu X, Savage V, Matalon D, Gardner EL. Genetic differences in delta 9-tetrahydrocannabinol-induced facilitation of brain stimulation reward as measured by a rate-frequency curve-shift electrical brain stimulation paradigm in three different rat strains. Life Sciences. 58: PL365-72. PMID 8649214 DOI: 10.1016/0024-3205(96)00237-8  1
1996 Chen J, Marmur R, Paredes W, Pulles A, Gardner EL. Systemic cocaine challenge after chronic cocaine treatment reveals sensitization of extracellular dopamine levels in nucleus accumbens but direct cocaine perfusion into nucleus accumbens does not: Implications for the neural locus of cocaine sensitization Life Sciences. 58. PMID 8594313  1
1995 Lepore M, Vorel SR, Lowinson J, Gardner EL. Conditioned place preference induced by delta 9-tetrahydrocannabinol: comparison with cocaine, morphine, and food reward. Life Sciences. 56: 2073-80. PMID 7776834 DOI: 10.1016/0024-3205(95)00191-8  1
1994 Gardner EL, Chen J, Paredes W. Clozapine produces potent antidopaminergic effects anatomically specific to the mesolimbic system Journal of Clinical Psychiatry. 55: 15-22. PMID 7961561  1
1993 Gardner EL, Chen J, Paredes W. Overview of chemical sampling techniques Journal of Neuroscience Methods. 48: 173-197. PMID 8412302 DOI: 10.1016/0165-0270(93)90091-5  1
1993 Jabotinsky-Rubin K, Durst R, Levitin LA, Moscovich DG, Silver H, Lerner J, Van Praag H, Gardner EL. Effects of haloperidol on human plasma magnesium. Journal of Psychiatric Research. 27: 155-9. PMID 8366466 DOI: 10.1016/0022-3956(93)90003-K  1
1993 Chen J, Marmur R, Pulles A, Paredes W, Gardner EL. Ventral tegmental microinjection of Δ9-tetrahydrocannabinol enhances ventral tegmental somatodendritic dopamine levels but not forebrain dopamine levels: evidence for local neural action by marijuana's psychoactive ingredient Brain Research. 621: 65-70. PMID 8221074 DOI: 10.1016/0006-8993(93)90298-2  1
1993 Gardner EL, Walker LS, Paredes W. Clozapine's functional mesolimbic selectivity is not duplicated by the addition of anticholinergic action to haloperidol: a brain stimulation study in the rat Psychopharmacology. 110: 119-124. PMID 7870870 DOI: 10.1007/BF02246960  1
1993 Gardner EL, Lowinson JH. Drug craving and positive/negative hedonic brain substrates activated by addicting drugs Seminars in Neuroscience. 5: 359-368. DOI: 10.1016/S1044-5765(05)80044-2  1
1993 Gardner EL. Introduction: The neurobiology of drug addiction/dependency Seminars in Neuroscience. 5: 313-314. DOI: 10.1016/S1044-5765(05)80037-5  1
1992 Chen J, Ruan D, Paredes W, Gardner EL. Effects of acute and chronic clozapine on dopaminergic function in medial prefrontal cortex of awake, freely moving rats Brain Research. 571: 235-241. PMID 1611497 DOI: 10.1016/0006-8993(92)90660-2  1
1992 Chen J, Paredes W, Van Praag HM, Lowinson JH, Gardner EL. Presynaptic dopamine release is enhanced by 5-HT3 receptor activation in medial prefrontal cortex of freely moving rats. Synapse (New York, N.Y.). 10: 264-6. PMID 1557698 DOI: 10.1002/syn.890100308  1
1992 Chen J, Paredes W, van Praag HM, Gardner EL. Serotonin denervation enhances responsiveness of presynaptic dopamine efflux to acute clozapine in nucleus accumbens but not in caudate-putamen. Brain Research. 582: 173-9. PMID 1379872 DOI: 10.1016/0006-8993(92)90335-7  1
1991 Chen J, Paredes W, Gardner EL. Chronic treatment with clozapine selectively decreases basal dopamine release in nucleus accumbens but not in caudate-putamen as measured by in vivo brain microdialysis: Further evidence for depolarization block Neuroscience Letters. 122: 127-131. PMID 2057129 DOI: 10.1016/0304-3940(91)90209-C  1
1991 Gardner EL, Lowinson JH. Marijuana's interaction with brain reward systems: Update 1991 Pharmacology, Biochemistry and Behavior. 40: 571-580. PMID 1806947 DOI: 10.1016/0091-3057(91)90365-9  1
1991 Chen JP, van Praag HM, Gardner EL. Activation of 5-HT3 receptor by 1-phenylbiguanide increases dopamine release in the rat nucleus accumbens. Brain Research. 543: 354-7. PMID 1711914 DOI: 10.1016/0006-8993(91)90050-6  1
1991 Chen J, Paredes W, Lowinson JH, Gardner EL. Strain-specific facilitation of dopamine efflux by Δ9-tetrahydrocannabinol in the nucleus accumbens of rat: An in vivo microdialysis study Neuroscience Letters. 129: 136-140. PMID 1656336 DOI: 10.1016/0304-3940(91)90739-G  1
1990 Chen J, Paredes W, Li J, Smith D, Lowinson J, Gardner EL. Δ9-Tetrahydrocannabinol produces naloxone-blockable enhancement of presynaptic basal dopamine efflux in nucleus accumbens of conscious, freely-moving rats as measured by intracerebral microdialysis Psychopharmacology. 102: 156-162. PMID 2177204 DOI: 10.1007/BF02245916  1
1990 Jianping C, Paredes W, Lowinson JH, Gardner EL. Δ9-Tetrahydroeannabinol enhances presynaptic dopamine efflux In medial prefrontal cortex European Journal of Pharmacology. 190: 259-262. PMID 1963849 DOI: 10.1016/0014-2999(90)94136-L  1
1990 Gardner EL, Chen J, Paredes W, Smith D, Li J, Lowinson J. Enhancement of presynaptic dopamine efflux in brain by Δ9-tetrahydro-cannabinol is mediated by an endogenous opioid mechanism New Leads in Opioid Research: Proceedings of the International Narcotics Research Conference. Ics914. 243.  1
1988 Ng Cheong Ton JM, Gerhardt GA, Friedemann M, Etgen AM, Rose GM, Sharpless NS, Gardner EL. The effects of delta 9-tetrahydrocannabinol on potassium-evoked release of dopamine in the rat caudate nucleus: an in vivo electrochemical and in vivo microdialysis study. Brain Research. 451: 59-68. PMID 2855215 DOI: 10.1016/0006-8993(88)90749-4  1
1988 Gardner EL, Paredes W, Smith D, Donner A, Milling C, Cohen D, Morrison D. Facilitation of brain stimulation reward by Δ 9-tetrahydrocannabinol Psychopharmacology. 96: 142-144. PMID 2852376 DOI: 10.1007/BF02431546  1
1988 Gardner EL, Seeger TF. Anatomically selective action of atypical neuroleptics on the mesocorticolimbic dopamine system Annals of the New York Academy of Sciences. 537: 502-504.  1
1987 Vaysse PJ, Gardner EL, Zukin RS. Modulation of rat brain opioid receptors by cannabinoids. The Journal of Pharmacology and Experimental Therapeutics. 241: 534-9. PMID 3033219  1
1987 Eghbali M, Santoro C, Paredes W, Gardner EL, Zukin RS. Visualization of multiple opioid-receptor types in rat striatum after specific mesencephalic lesions. Proceedings of the National Academy of Sciences of the United States of America. 84: 6582-6. PMID 2819882  1
1986 Zukin SR, Tempel A, Gardner EL, Zukin RS. Interaction of [3H](-)-SKF-10,047 with brain sigma receptors: characterization and autoradiographic visualization. Journal of Neurochemistry. 46: 1032-41. PMID 3005501 DOI: 10.1111/j.1471-4159.1986.tb00614.x  1
1985 Tempel A, Gardner EL, Zukin RS. Neurochemical and functional correlates of naltrexone-induced opiate receptor up-regulation. The Journal of Pharmacology and Experimental Therapeutics. 232: 439-44. PMID 2982011  1
1984 Broderick PA, Gardner EL, Van Praag HM. In vivo electrochemical and behavioral evidence for specific neural substrates modulated differentially by enkephalin in rat stimulant stereotypy and locomotion Biological Psychiatry. 19: 45-54. PMID 6538442  1
1984 Tempel A, Gardner EL, Zukin RS. Visualization of opiate receptor upregulation by light microscopy autoradiography. Proceedings of the National Academy of Sciences of the United States of America. 81: 3893-7. PMID 6328530  1
1984 Zukin RS, Tempel A, Gardner EL. Opiate receptor upregulation and functional supersensitivity. Nida Research Monograph. 54: 146-61. PMID 6099871  1
1983 Broderick PA, Gardner EL, van Praag HM. Similar effects of an enkephalin analog on mesolimbic dopamine release and hyperactivity in rats Life Sciences. 33: 635-638. PMID 6686641 DOI: 10.1016/0024-3205(83)90583-0  1
1983 Gardner EL, Seeger TF. Neurobehavioral evidence for mesolimbic specificity of action by clozapine: Studies using electrical intracranial self-stimulation Biological Psychiatry. 18: 1357-1362. PMID 6661466  1
1983 Hirschhorn ID, Hittner D, Gardner EL, Cubells J, Makman MH. Evidence for a role of endogenous opioids in the nigrostriatal system: Influence of naloxone and morphine on nigrostriatal dopaminergic supersensitivity Brain Research. 270: 109-117. PMID 6409355 DOI: 10.1016/0006-8993(83)90796-5  1
1982 Marotta RF, Logan N, Riverso S, Gardner EL. Mitigation of the septal lesion syndrome by pre-lesion chronic treatment with haloperidol Pharmacology, Biochemistry and Behavior. 16: 769-775. PMID 7089035 DOI: 10.1016/0091-3057(82)90233-7  1
1982 Seeger TF, Thal L, Gardner EL. Behavioral and biochemical aspects of neuroleptic-induced dopaminergic supersensitivity: Studies with chronic clozapine and haloperidol Psychopharmacology. 76: 182-187. PMID 6805029 DOI: 10.1007/BF00435275  1
1982 Tempel A, Zukin RS, Gardner EL. Supersensitivity of brain opiate receptor subtypes after chronic naltrexone treatment. Life Sciences. 31: 1401-4. PMID 6292636 DOI: 10.1016/0024-3205(82)90391-5  1
1982 Zukin RS, Sugarman JR, Fitz-Syage ML, Gardner EL, Zukin SR, Gintzler AR. Naltrexone-induced opiate receptor supersensitivity. Brain Research. 245: 285-92. PMID 6289965 DOI: 10.1016/0006-8993(82)90811-3  1
1981 Nazzaro JM, Seeger TF, Gardner EL. Morphine differentially affects ventral tegmental and substantia nigra brain reward thresholds Pharmacology, Biochemistry and Behavior. 14: 325-331. PMID 7232458 DOI: 10.1016/0091-3057(81)90398-1  1
1981 Seeger TF, Gardner EL, Bridger WF. Increase in mesolimbic electrical self-stimulation after chronic haloperidol: reversal by L-DOPA or lithium Brain Research. 215: 404-409. PMID 6790126 DOI: 10.1016/0006-8993(81)90525-4  1
1981 Walczak SA, Makman MH, Gardner EL. Acetylmethadol metabolites influence opiate receptors and adenylate cyclase in amygdala European Journal of Pharmacology. 72: 343-349. PMID 6268422 DOI: 10.1016/0014-2999(81)90573-2  1
1980 Seeger TF, Nazzaro JM, Gardner EL. Selective inhibition of mesolimbic behavioral supersensitivity by naloxone European Journal of Pharmacology. 65: 435-438. PMID 7408948  1
1980 Nazzaro J, Gardner EL. GABA antagonism lowers self-stimulation thresholds in the ventral tegmental area Brain Research. 189: 279-283. PMID 7363095 DOI: 10.1016/0006-8993(80)90029-3  1
1980 Gardner EL, Zukin RS, Makman MH. Modulation of opiate receptor binding in striatum and amygdala by selective mesencephalic lesions. Brain Research. 194: 232-9. PMID 6247033 DOI: 10.1016/0006-8993(80)91335-9  1
1980 Hirschhorn ID, Makman MH, Gardner EL. Changes in guanine nucleotide sensitive and insensitive 3H-ADTN binding in striatum following substantia nigra lesions European Journal of Pharmacology. 62: 123-124. PMID 6154585 DOI: 10.1016/0014-2999(80)90490-2  1
1979 Thal L, Mishra RK, Gardner EL, Horowitz SG, Varmuza S, Makman MH. Dopamine antagonist binding increases in two behaviorally distinct striatal denervation syndromes Brain Research. 170: 381-386. PMID 572733 DOI: 10.1016/0006-8993(79)90119-7  1
1979 Rosenfeld MR, Seeger TF, Sharpless NS, Gardner EL, Makman MH. Denervation supersensitivity in the mesolimbic system: involvement of dopamine-stimulated adenylate cyclase Brain Research. 173: 572-576. PMID 487111 DOI: 10.1016/0006-8993(79)90255-5  1
1979 Seeger TF, Gardner EL. Enhancement of self-stimulation behavior in rats and monkeys after chronic neuroleptic treatment: Evidence for mesolimbic supersensitivity Brain Research. 175: 49-57. PMID 114275 DOI: 10.1016/0006-8993(79)90513-4  1
1977 Marotta RF, Logan N, Potegal M, Glusman M, Gardner EL. Dopamine agonists induce recovery from surgically-induced septal rage Nature. 269: 513-515. PMID 909599 DOI: 10.1038/269513a0  1
1976 Gardner EL, Mishra RK, Iordanidis P. Catalytic and receptor components of enhanced dopamine stimulated adenylate cyclase in 2 behaviorally distinct striatal denervation syndromes Federation Proceedings. 35.  1
1974 Mishra RK, Gardner EL, Katzman R, Makman MH. Enhancement of dopamine-stimulated adenylate cyclase activity in rat caudate after lesions in substantia nigra: evidence for denervation supersensitivity. Proceedings of the National Academy of Sciences of the United States of America. 71: 3883-7. PMID 4372596  1
1974 Jackson WJ, Gardner EL. Modulation of hypothalamic ICSS by concurrent limbic stimulation Physiology and Behavior. 12: 177-182. PMID 4205808 DOI: 10.1016/0031-9384(74)90170-X  1
1974 Mishra RK, Gardner EL, Wolotsky P. Changes in adenylate cyclase activity in rat caudate nuclei following lesions in substantia nigra Trans.Amer.Soc.Neurochem.. 5.  1
1972 Gardner EL, Glick SD, Jarvik ME. ECS dissociation of learning and one-way cross-dissociation with physostigmine and scopolamine. Physiology & Behavior. 8: 11-5. PMID 4677196 DOI: 10.1016/0031-9384(72)90121-7  1
1971 Routtenberg A, Gardner EL, Huang YH. Self-stimulation pathways in the monkey, Macaca mulatta. Experimental Neurology. 33: 213-24. PMID 4107565 DOI: 10.1016/0014-4886(71)90115-4  1
1971 Gardner EL, Engel DR. Imitational and social facilitatory aspects of observational learning in the laboratory rat Psychonomic Science. 25: 5-6. DOI: 10.3758/BF03335828  1
1971 Gardner EL. An improved technique for determining brain reward thresholds in primates Behavior Research Methods &Amp; Instrumentation. 3: 273-274. DOI: 10.3758/BF03208404  1
1970 Jackson WJ, Gardner EL. A method for rapid implantation of several intracranial electrodes Physiology and Behavior. 5: 827-829. PMID 4941876 DOI: 10.1016/0031-9384(70)90288-X  1
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