Year |
Citation |
Score |
2021 |
Hart NJ, Weber C, Price N, Banuelos A, Schultz M, Huey B, Harnois E, Gibson C, Steyn LV, Papas KK, Lynch RM. Insulinoma-derived pseudo-islets for diabetes research. American Journal of Physiology. Cell Physiology. PMID 34106785 DOI: 10.1152/ajpcell.00466.2020 |
0.516 |
|
2020 |
Weber C, Hart N, Steyn LV, Papas K, Lynch RM. Characterization of Islet Health and Function Prior to Transplantation The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.06703 |
0.475 |
|
2020 |
Lynch RM, Aragaki KA, Harnois E, Vagner J, Weber C. Kisspeptin Amplifies GLP‐1 Potentiation of Insulin Secretion by a cAMP Independent Pathway The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.06634 |
0.302 |
|
2019 |
Hart N, Weber C, Price N, Watson A, Lynch R, Steyn L, Papas KK. 68 Transplantation. 103: S24. DOI: 10.1097/01.Tp.0000581400.53697.6D |
0.511 |
|
2018 |
Hart NJ, Weber C, Papas KK, Limesand SW, Vagner J, Lynch RM. Multivalent activation of GLP-1 and Sulfonylurea receptors modulates β-cell Second Messenger Signaling and Insulin Secretion. American Journal of Physiology. Cell Physiology. PMID 30404557 DOI: 10.1152/Ajpcell.00209.2018 |
0.607 |
|
2018 |
Kelly AC, Camacho LE, Pendarvis K, Davenport HM, Steffens NR, Smith KE, Weber CS, Lynch RM, Papas KK, Limesand SW. Adrenergic receptor stimulation suppresses oxidative metabolism in isolated rat islets and Min6 cells. Molecular and Cellular Endocrinology. PMID 29360563 DOI: 10.1016/J.Mce.2018.01.012 |
0.372 |
|
2017 |
McKay BS, Lynch RM, Stamer WD. Comment on "Identification of Novel G Protein-Coupled Receptor 143 Ligands as Pharmacologic Tools for Investigating X-Linked Ocular Albinism". Investigative Ophthalmology & Visual Science. 58: 4733-4734. PMID 28910826 DOI: 10.1167/Iovs.17-22660 |
0.302 |
|
2017 |
Smith KE, Kelly AC, Min CG, Weber CS, McCarthy FM, Steyn LV, Badarinarayana V, Stanton JB, Kitzmann JP, Strop P, Gruessner AC, Lynch RM, Limesand SW, Papas KK. Acute Ischemia Induced by High Density Culture Increases Cytokine Expression and Diminishes the Function and Viability of Highly Purified Human Islets of Langerhans. Transplantation. PMID 28263224 DOI: 10.1097/Tp.0000000000001714 |
0.332 |
|
2016 |
Chen X, Kelly AC, Yates DT, Macko AR, Lynch RM, Limesand SW. Islet adaptations in fetal sheep persist following chronic exposure to high norepinephrine. The Journal of Endocrinology. PMID 27888197 DOI: 10.1530/Joe-16-0445 |
0.333 |
|
2015 |
Steyn LV, Ananthakrishnan K, Anderson MJ, Patek R, Kelly A, Vagner J, Lynch RM, Limesand SW. A Synthetic Heterobivalent Ligand Composed of Glucagon-Like Peptide 1 and Yohimbine Specifically Targets β Cells Within the Pancreas. Molecular Imaging and Biology : Mib : the Official Publication of the Academy of Molecular Imaging. 17: 461-70. PMID 25604385 DOI: 10.1007/S11307-014-0817-1 |
0.304 |
|
2014 |
Kelly AC, Steyn LV, Kitzmann JP, Anderson MJ, Mueller KR, Hart NJ, Lynch RM, Papas KK, Limesand SW. Function and expression of sulfonylurea, adrenergic, and glucagon-like peptide 1 receptors in isolated porcine islets. Xenotransplantation. 21: 385-91. PMID 24801676 DOI: 10.1111/Xen.12101 |
0.565 |
|
2014 |
Hart NJ, Chung WJ, Weber C, Ananthakrishnan K, Anderson M, Patek R, Zhang Z, Limesand SW, Vagner J, Lynch RM. Hetero-bivalent GLP-1/glibenclamide for targeting pancreatic β-cells. Chembiochem : a European Journal of Chemical Biology. 15: 135-45. PMID 24259278 DOI: 10.1002/Cbic.201300375 |
0.569 |
|
2013 |
Escalante AM, McGrath RT, Karolak MR, Dorr RT, Lynch RM, Landowski TH. Preventing the autophagic survival response by inhibition of calpain enhances the cytotoxic activity of bortezomib in vitro and in vivo. Cancer Chemotherapy and Pharmacology. 71: 1567-76. PMID 23572175 DOI: 10.1007/S00280-013-2156-3 |
0.331 |
|
2013 |
Brabez N, Saunders K, Nguyen KL, Jayasundera TB, Weber C, Lynch RM, Chassaing G, Lavielle S, Hruby VJ. Multivalent Interactions: Synthesis and Evaluation of Melanotropin Multimers - Tools for Melanoma Targeting. Acs Medicinal Chemistry Letters. 4: 98-102. PMID 23524643 DOI: 10.1021/Ml300312B |
0.303 |
|
2013 |
Martinez-Zaguilan R, Tompkins LS, Gillies RJ, Lynch RM. Simultaneous analysis of intracellular pH and Ca²⺠from cell populations. Methods in Molecular Biology (Clifton, N.J.). 937: 253-71. PMID 23007592 DOI: 10.1007/978-1-62703-086-1_16 |
0.611 |
|
2013 |
Martinez-Zaguilan R, Tompkins LS, Gillies RJ, Lynch RM. Simultaneous analysis of intracellular pH and Ca2+ from cell populations Methods in Molecular Biology. 937: 253-271. DOI: 10.1007/978-1-62703-86-1_16 |
0.606 |
|
2012 |
Xu L, Josan JS, Vagner J, Caplan MR, Hruby VJ, Mash EA, Lynch RM, Morse DL, Gillies RJ. Heterobivalent ligands target cell-surface receptor combinations in vivo. Proceedings of the National Academy of Sciences of the United States of America. 109: 21295-300. PMID 23236171 DOI: 10.1073/Pnas.1211762109 |
0.305 |
|
2012 |
Green AS, Chen X, Macko AR, Anderson MJ, Kelly AC, Hart NJ, Lynch RM, Limesand SW. Chronic pulsatile hyperglycemia reduces insulin secretion and increases accumulation of reactive oxygen species in fetal sheep islets. The Journal of Endocrinology. 212: 327-42. PMID 22182602 DOI: 10.1530/Joe-11-0300 |
0.539 |
|
2011 |
Josan JS, Handl HL, Sankaranarayanan R, Xu L, Lynch RM, Vagner J, Mash EA, Hruby VJ, Gillies RJ. Cell-specific targeting by heterobivalent ligands. Bioconjugate Chemistry. 22: 1270-8. PMID 21639139 DOI: 10.1021/Bc1004284 |
0.335 |
|
2010 |
Pritchard TJ, Bowman PS, Jefferson A, Tosun M, Lynch RM, Paul RJ. Na(+)-K(+)-ATPase and Ca(2+) clearance proteins in smooth muscle: a functional unit. American Journal of Physiology. Heart and Circulatory Physiology. 299: H548-56. PMID 20543086 DOI: 10.1152/Ajpheart.00527.2009 |
0.316 |
|
2010 |
De Silva CR, Vagner J, Lynch R, Gillies RJ, Hruby VJ. Optimization of time-resolved fluorescence assay for detection of europium-tetraazacyclododecyltetraacetic acid-labeled ligand-receptor interactions. Analytical Biochemistry. 398: 15-23. PMID 19852924 DOI: 10.1016/J.Ab.2009.10.031 |
0.306 |
|
2009 |
Xu L, Vagner J, Josan J, Lynch RM, Morse DL, Baggett B, Han H, Mash EA, Hruby VJ, Gillies RJ. Enhanced targeting with heterobivalent ligands. Molecular Cancer Therapeutics. 8: 2356-65. PMID 19671749 DOI: 10.1158/1535-7163.Mct-08-1183 |
0.329 |
|
2008 |
Xu H, Chen H, Dong J, Lynch R, Ghishan FK. Gastrointestinal distribution and kinetic characterization of the sodium-hydrogen exchanger isoform 8 (NHE8). Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology. 21: 109-16. PMID 18209477 DOI: 10.1159/000113752 |
0.325 |
|
2008 |
Lynch RM, Weber CS, Nullmeyer KD, Moore ED, Paul RJ. Clearance of store-released Ca2+ by the Na+-Ca2+ exchanger is diminished in aortic smooth muscle from Na+-K+-ATPase alpha 2-isoform gene-ablated mice. American Journal of Physiology. Heart and Circulatory Physiology. 294: H1407-16. PMID 18192219 DOI: 10.1152/Ajpheart.00855.2007 |
0.316 |
|
2008 |
Landowski TH, Escalante AM, Jefferson A, Dorr RT, Lynch R. Inhibition of Autophagy Promotes Bortezomib-Mediated Cell Death in Myeloma Cells Blood. 112: 3677-3677. DOI: 10.1182/Blood.V112.11.3677.3677 |
0.345 |
|
2007 |
Lynch RM, Barthelson R, Cates J, Brooks HL, Galbraith DW. Nucleomics of glucose sensing cells: methodology for cell‐type specific analysis of gene expression The Faseb Journal. 21. DOI: 10.1096/Fasebj.21.5.A476-D |
0.34 |
|
2006 |
Martinez-Zaguilan R, Tompkins LS, Gillies RJ, Lynch RM. Simultaneous analysis of intracellular pH and Ca2+ from cell populations. Methods in Molecular Biology (Clifton, N.J.). 312: 269-87. PMID 16422205 |
0.606 |
|
2005 |
Martinez-Zaguilan R, Tompkins LS, Gillies RJ, Lynch RM. Simultaneous analysis of intracellular pH and Ca²+ from cell populations. Methods in Molecular Biology (Clifton, N.J.). 312: 269-87. PMID 21341106 DOI: 10.1385/1-59259-949-4:269 |
0.645 |
|
2005 |
Landowski TH, Megli CJ, Nullmeyer KD, Lynch RM, Dorr RT. Mitochondrial-mediated disregulation of Ca2+ is a critical determinant of Velcade (PS-341/bortezomib) cytotoxicity in myeloma cell lines. Cancer Research. 65: 3828-36. PMID 15867381 DOI: 10.1158/0008-5472.Can-04-3684 |
0.354 |
|
2005 |
Sutherland VL, McReynolds M, Tompkins LS, Brooks HL, Lynch RM. Developmental expression of glucokinase in rat hypothalamus. Brain Research. Developmental Brain Research. 154: 255-8. PMID 15707679 DOI: 10.1016/J.Devbrainres.2004.11.001 |
0.707 |
|
2002 |
Tompkins LS, Nullmeyer KD, Murphy SM, Weber CS, Lynch RM. Regulation of secretory granule pH in insulin-secreting cells. American Journal of Physiology. Cell Physiology. 283: C429-37. PMID 12107052 DOI: 10.1152/Ajpcell.01066.2000 |
0.65 |
|
2001 |
Gillies RJ, Lynch RM. Frontiers in the measurement of cell and tissue pH. Novartis Foundation Symposium. 240: 7-19; discussion 19-. PMID 11727938 DOI: 10.1002/0470868716.Ch2 |
0.311 |
|
2000 |
Lynch RM, Tompkins LS, Brooks HL, Dunn-Meynell AA, Levin BE. Localization of glucokinase gene expression in the rat brain. Diabetes. 49: 693-700. PMID 10905475 DOI: 10.2337/Diabetes.49.5.693 |
0.594 |
|
1999 |
Martinez-Zaguilan R, Tompkins LS, Gillies RJ, Lynch RM. Simultaneous analysis of intracellular pH and Ca2+ from cell populations. Methods in Molecular Biology (Clifton, N.J.). 114: 287-306. PMID 10081026 DOI: 10.1385/1-59259-250-3:287 |
0.606 |
|
1997 |
Tompkins LS, Stickney GS, Parnami G, Lynch RM. Identification of Ca 2+ fluoro-probe loaded and GFP targeted compartments in single cells Faseb Journal. 11: A273. |
0.582 |
|
1996 |
Martínez-Zaguilán R, Parnami G, Lynch RM. Selection of fluorescent ion indicators for simultaneous measurements of pH and Ca2+ Cell Calcium. 19: 337-349. PMID 8983854 DOI: 10.1016/S0143-4160(96)90074-3 |
0.364 |
|
1996 |
Martínez-Zaguilán R, Gurulé MW, Lynch RM. Simultaneous measurement of intracellular pH and Ca2+ in insulin-secreting cells by spectral imaging microscopy American Journal of Physiology - Cell Physiology. 270. PMID 8967445 DOI: 10.1152/Ajpcell.1996.270.5.C1438 |
0.392 |
|
1996 |
Lynch RM, Carrington W, Fogarty KE, Fay FS. Metabolic modulation of hexokinase association with mitochondria in living smooth muscle cells American Journal of Physiology - Cell Physiology. 270. PMID 8779911 DOI: 10.1152/Ajpcell.1996.270.2.C488 |
0.332 |
|
1996 |
Becker TC, Noel RJ, Johnson JH, Lynch RM, Hirose H, Tokuyama Y, Bell GI, Newgard CB. Differential effects of overexpressed glucokinase and hexokinase I in isolated islets. Evidence for functional segregation of the high and low Km enzymes. The Journal of Biological Chemistry. 271: 390-4. PMID 8550593 DOI: 10.1074/Jbc.271.1.390 |
0.387 |
|
1993 |
Martinez-Zaguilan R, Lynch RM, Martinez GM, Gillies RJ. Vacuolar-type H(+)-ATPases are functionally expressed in plasma membranes of human tumor cells. The American Journal of Physiology. 265: C1015-29. PMID 8238296 DOI: 10.1152/Ajpcell.1993.265.4.C1015 |
0.309 |
|
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