| Year |
Citation |
Score |
| 2017 |
Ke S, Anquetil V, Zamalloa JR, Maity A, Yang A, Arias MA, Kalachikov S, Russo JJ, Ju J, Chasin LA. Saturation mutagenesis reveals manifold determinants of exon definition. Genome Research. PMID 29242188 DOI: 10.1101/Gr.219683.116 |
0.629 |
|
| 2016 |
Solé A, Ciudad CJ, Chasin LA, Noé V. Correction of point mutations at the endogenous locus of the dihydrofolate reductase gene using repair-PolyPurine Reverse Hoogsteen hairpins in mammalian cells. Biochemical Pharmacology. PMID 27063945 DOI: 10.1016/j.bcp.2016.04.002 |
0.321 |
|
| 2015 |
Arias MA, Lubkin A, Chasin LA. Splicing of designer exons informs a biophysical model for exon definition. Rna (New York, N.Y.). 21: 213-29. PMID 25492963 DOI: 10.1261/rna.048009.114 |
0.496 |
|
| 2011 |
Ke S, Shang S, Kalachikov SM, Morozova I, Yu L, Russo JJ, Ju J, Chasin LA. Quantitative evaluation of all hexamers as exonic splicing elements. Genome Research. 21: 1360-74. PMID 21659425 DOI: 10.1101/Gr.119628.110 |
0.679 |
|
| 2011 |
Ke S, Chasin LA. Context-dependent splicing regulation: exon definition, co-occurring motif pairs and tissue specificity. Rna Biology. 8: 384-8. PMID 21444999 DOI: 10.4161/Rna.8.3.14458 |
0.617 |
|
| 2010 |
Ke S, Chasin LA. Intronic motif pairs cooperate across exons to promote pre-mRNA splicing. Genome Biology. 11: R84. PMID 20704715 DOI: 10.1186/Gb-2010-11-8-R84 |
0.635 |
|
| 2010 |
Arias MA, Ke S, Chasin LA. Splicing by cell type. Nature Biotechnology. 28: 686-7. PMID 20622839 DOI: 10.1038/Nbt0710-686 |
0.583 |
|
| 2009 |
Zhang XH, Arias MA, Ke S, Chasin LA. Splicing of designer exons reveals unexpected complexity in pre-mRNA splicing. Rna (New York, N.Y.). 15: 367-76. PMID 19155327 DOI: 10.1261/Rna.1498509 |
0.671 |
|
| 2008 |
Yu Y, Maroney PA, Denker JA, Zhang XHF, Dybkov O, Lührmann R, Jankowsky E, Chasin LA, Nilsen TW. Dynamic Regulation of Alternative Splicing by Silencers that Modulate 5′ Splice Site Competition Cell. 135: 1224-1236. PMID 19109894 DOI: 10.1016/J.Cell.2008.10.046 |
0.471 |
|
| 2008 |
Ke S, Zhang XH, Chasin LA. Positive selection acting on splicing motifs reflects compensatory evolution. Genome Research. 18: 533-43. PMID 18204002 DOI: 10.1101/Gr.070268.107 |
0.662 |
|
| 2007 |
Chasin LA. Searching for splicing motifs. Advances in Experimental Medicine and Biology. 623: 85-106. PMID 18380342 |
0.58 |
|
| 2006 |
Zhang XH, Chasin LA. Comparison of multiple vertebrate genomes reveals the birth and evolution of human exons. Proceedings of the National Academy of Sciences of the United States of America. 103: 13427-32. PMID 16938881 DOI: 10.1073/pnas.0603042103 |
0.329 |
|
| 2005 |
Zhang XH, Leslie CS, Chasin LA. Computational searches for splicing signals. Methods (San Diego, Calif.). 37: 292-305. PMID 16314258 DOI: 10.1016/j.ymeth.2005.07.011 |
0.467 |
|
| 2005 |
Zhang XH, Kangsamaksin T, Chao MS, Banerjee JK, Chasin LA. Exon inclusion is dependent on predictable exonic splicing enhancers. Molecular and Cellular Biology. 25: 7323-32. PMID 16055740 DOI: 10.1128/Mcb.25.16.7323-7332.2005 |
0.501 |
|
| 2005 |
Zhang XH, Leslie CS, Chasin LA. Dichotomous splicing signals in exon flanks. Genome Research. 15: 768-79. PMID 15930489 DOI: 10.1101/gr.3217705 |
0.425 |
|
| 2004 |
Zhang XH, Chasin LA. Computational definition of sequence motifs governing constitutive exon splicing. Genes & Development. 18: 1241-50. PMID 15145827 DOI: 10.1101/gad.1195304 |
0.563 |
|
| 2003 |
Zhang XH, Heller KA, Hefter I, Leslie CS, Chasin LA. Sequence information for the splicing of human pre-mRNA identified by support vector machine classification. Genome Research. 13: 2637-50. PMID 14656968 DOI: 10.1101/gr.1679003 |
0.528 |
|
| 2003 |
Zhang X, Lee J, Chasin LA. The effect of nonsense codons on splicing: a genomic analysis. Rna (New York, N.Y.). 9: 637-9. PMID 12756320 DOI: 10.1261/Rna.5060403 |
0.491 |
|
| 2000 |
Fairbrother WG, Chasin LA. Human genomic sequences that inhibit splicing. Molecular and Cellular Biology. 20: 6816-25. PMID 10958678 DOI: 10.1128/Mcb.20.18.6816-6825.2000 |
0.509 |
|
| 2000 |
Sun H, Chasin LA. Multiple splicing defects in an intronic false exon. Molecular and Cellular Biology. 20: 6414-25. PMID 10938119 DOI: 10.1128/Mcb.20.17.6414-6425.2000 |
0.661 |
|
| 1999 |
Noé V, Ciudad CJ, Chasin LA. Effect of differential polyadenylation and cell growth phase on dihydrofolate reductase mRNA stability Journal of Biological Chemistry. 274: 27807-27814. PMID 10488126 DOI: 10.1074/jbc.274.39.27807 |
0.331 |
|
| 1999 |
Bai Y, Lee D, Yu T, Chasin LA. Control of 3' splice site choice in vivo by ASF/SF2 and hnRNP A1 Nucleic Acids Research. 27: 1126-1134. PMID 9927747 DOI: 10.1093/nar/27.4.1126 |
0.361 |
|
| 1996 |
Kessler O, Chasin LA. Effects of nonsense mutations on nuclear and cytoplasmic adenine phosphoribosyltransferase RNA Molecular and Cellular Biology. 16: 4426-4435. PMID 8754843 |
0.363 |
|
| 1994 |
Chen IT, Chasin LA. Large exon size does not limit splicing in vivo Molecular and Cellular Biology. 14: 2140-2146. PMID 8114744 |
0.439 |
|
| 1993 |
Chen IT, Chasin LA. Direct Selection for Mutations Affecting Specific Splice Sites in a Hamster Dihydrofolate Reductase Minigene Molecular and Cellular Biology. 13: 289-300. PMID 8417332 |
0.544 |
|
| 1993 |
Kessler O, Jiang Y, Chasin LA. Order of intron removal during splicing of endogenous adenine phosphoribosyltransferase and dihydrofolate reductase pre-mRNA Molecular and Cellular Biology. 13: 6211-6222. PMID 8413221 |
0.49 |
|
| 1993 |
Carothers AM, Urlaub G, Grunberger D, Chasin LA. Splicing mutants and their second-site suppressors at the dihydrofolate reductase locus in Chinese hamster ovary cells. Molecular and Cellular Biology. 13: 5085-98. PMID 8336736 DOI: 10.1128/Mcb.13.8.5085 |
0.489 |
|
| 1993 |
Carothers AM, Urlaub G, Mucha J, Yuan W, Chasin LA, Grunberger D. A mutational hot spot induced by N-hydroxy-aminofluorene in dihydrofolate reductase mutants of Chinese hamster ovary cells. Carcinogenesis. 14: 2181-4. PMID 8222072 DOI: 10.1093/Carcin/14.10.2181 |
0.338 |
|
| 1992 |
Ciudad CJ, Morris AE, Jeng C, Chasin LA. Point mutational analysis of the hamster dihydrofolate reductase minimum promoter Journal of Biological Chemistry. 267: 3650-3656. PMID 1740417 |
0.477 |
|
| 1992 |
Morris AE, Kloss B, Mcchesney RE, Bancroft C, Chasin LA. An alternatively spliced pit-1 isoform altered in its ability to trans-activate Nucleic Acids Research. 20: 1355-1361. PMID 1561093 DOI: 10.1093/nar/20.6.1355 |
0.359 |
|
| 1990 |
Carothers AM, Urlaub G, Mucha J, Harvey RG, Chasin LA, Grunberger D. Splicing mutations in the CHO DHFR gene preferentially induced by (+/-)-3 alpha,4 beta-dihydroxy-1 alpha,2 alpha-epoxy-1,2,3,4- tetrahydrobenzo[c]phenanthrene. Proceedings of the National Academy of Sciences of the United States of America. 87: 5464-8. PMID 2371281 DOI: 10.1073/Pnas.87.14.5464 |
0.323 |
|
| 1989 |
Urlaub G, Mitchell PJ, Ciudad CJ, Chasin LA. Nonsense mutations in the dihydrofolate reductase gene affect RNA processing Molecular and Cellular Biology. 9: 2868-2880. PMID 2779551 |
0.346 |
|
| 1989 |
Carothers AM, Urlaub G, Mucha J, Grunberger D, Chasin LA. Point mutation analysis in a mammalian gene: rapid preparation of total RNA, PCR amplification of cDNA, and Taq sequencing by a novel method. Biotechniques. 7: 494-6, 498-9. PMID 2483818 |
0.43 |
|
| 1989 |
Carothers AM, Steigerwalt RW, Urlaub G, Chasin LA, Grunberger D. DNA base changes and RNA levels in N-acetoxy-2-acetylaminofluorene-induced dihydrofolate reductase mutants of Chinese hamster ovary cells. Journal of Molecular Biology. 208: 417-28. PMID 2477551 DOI: 10.1016/0022-2836(89)90506-8 |
0.369 |
|
| 1988 |
Ciudad CJ, Urlaub G, Chasin LA. Deletion analysis of the Chinese hamster dihydrofolate reductase gene promoter Journal of Biological Chemistry. 263: 16274-16282. PMID 3182792 |
0.454 |
|
| 1988 |
Carothers AM, Urlaub G, Grunberger D, Chasin LA. Mapping and characterization of mutations induced by benzo[a]pyrene diol epoxide at dihydrofolate reductase locus in CHO cells. Somatic Cell and Molecular Genetics. 14: 169-83. PMID 2831629 DOI: 10.1007/Bf01534402 |
0.431 |
|
| 1987 |
Venolia L, Urlaub G, Chasin LA. Polyadenylation of Chinese hamster dihydrofolate reductase genomic genes and minigenes after gene transfer Somatic Cell and Molecular Genetics. 13: 491-504. PMID 3477873 DOI: 10.1007/BF01534491 |
0.429 |
|
| 1987 |
Käs E, Chasin LA. Anchorage of the Chinese hamster dihydrofolate reductase gene to the nuclear scaffold occurs in an intragenic region Journal of Molecular Biology. 198: 677-692. PMID 3430625 DOI: 10.1016/0022-2836(87)90209-9 |
0.327 |
|
| 1986 |
Mitchell PJ, Urlaub G, Chasin L. Spontaneous splicing mutations at the dihydrofolate reductase locus in Chinese hamster ovary cells Molecular and Cellular Biology. 6: 1926-1935. PMID 3023911 DOI: 10.1128/Mcb.6.6.1926 |
0.524 |
|
| 1986 |
Mitchell PJ, Carothers AM, Han JH, Harding JD, Kas E, Venolia L, Chasin LA. Multiple transcription start sites, DNase I-hypersensitive sites, and an opposite-strand exon in the 5' region of the CHO dhfr gene Molecular and Cellular Biology. 6: 425-440. PMID 3023846 |
0.378 |
|
| 1986 |
Carothers AM, Urlaub G, Steigerwalt RW, Chasin LA, Grunberger D. Characterization of mutations induced by 2-(N-acetoxy-N-acetyl)aminofluorene in the dihydrofolate reductase gene of cultured hamster cells. Proceedings of the National Academy of Sciences of the United States of America. 83: 6519-23. PMID 3018736 DOI: 10.1073/Pnas.83.17.6519 |
0.337 |
|
| 1983 |
Carothers AM, Urlaub G, Ellis N, Chasin LA. Structure of the dihydrofolate reductase gene in chinese hamster ovary cells Nucleic Acids Research. 11: 1997-2012. PMID 6300788 DOI: 10.1093/nar/11.7.1997 |
0.3 |
|
| 1969 |
Kao F, Chasin L, Puck TT. Genetics of somatic mammalian cells. X. Complementation analysis of glycine-requiring mutants. Proceedings of the National Academy of Sciences of the United States of America. 64: 1284-91. PMID 5271752 DOI: 10.1073/Pnas.64.4.1284 |
0.303 |
|
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