| Year |
Citation |
Score |
| 2024 |
de Guglielmo G, Carrette L, Kallupi M, Brennan M, Boomhower B, Maturin L, Conlisk D, Sedighim S, Tieu L, Fannon MJ, Martinez AR, Velarde N, Othman D, Sichel B, Ramborger J, ... ... George O, et al. Large-scale characterization of cocaine addiction-like behaviors reveals that escalation of intake, aversion-resistant responding, and breaking-points are highly correlated measures of the same construct. Elife. 12. PMID 39484794 DOI: 10.7554/eLife.90422 |
0.798 |
|
| 2024 |
Logan R, Shelton M, Horan N, Xue X, Maturin L, Eacret D, Michaud J, Singh N, Williams B, Gamble M, Seggio J, Kuppe-Fish M, Phan B, Tseng G, Blendy J, ... ... George O, et al. Sex-specific Concordance of Striatal Transcriptional Signatures of Opioid Addiction in Human and Rodent Brains. Research Square. PMID 39399686 DOI: 10.21203/rs.3.rs-5006061/v1 |
0.803 |
|
| 2024 |
Okamoto F, Chitre AS, Sanches TM, Chen D, Munro D, Aron AT, Beeson A, Bimschleger HV, Eid M, Martinez AGG, Han W, Holl K, Jackson T, Johnson BB, King CP, ... ... George O, et al. Y and Mitochondrial Chromosomes in the Heterogeneous Stock Rat Population. G3 (Bethesda, Md.). PMID 39250761 DOI: 10.1093/g3journal/jkae213 |
0.771 |
|
| 2024 |
Shankar K, Bonnet-Zahedi S, Milan K, D'argence AR, Sneddon E, Qiao R, Chonwattangul S, Carrette LL, Kallupi M, George O. Acute nicotine activates orectic and inhibits anorectic brain regions in rats exposed to chronic nicotine. Neuropharmacology. 109959. PMID 38648925 DOI: 10.1016/j.neuropharm.2024.109959 |
0.805 |
|
| 2024 |
Mason BJ, Estey D, Roberts A, de Guglielmo G, George O, Light J, Stoolmiller M, Quello S, Skinner M, Shadan F, Begovic A, Kyle MC, Harris RA. A reverse translational study of PPAR-α agonist efficacy in human and rodent models relevant to alcohol use disorder. Neurobiology of Stress. 29: 100604. PMID 38292518 DOI: 10.1016/j.ynstr.2023.100604 |
0.66 |
|
| 2023 |
Shankar K, Ramborger J, Bonnet-Zahedi S, Carrette LLG, George O. Acute nicotine intake increases feeding behavior through decreasing glucagon signaling in dependent male and female rats. Hormones and Behavior. 105447. PMID 37926623 DOI: 10.1016/j.yhbeh.2023.105447 |
0.811 |
|
| 2023 |
Zhou JL, de Guglielmo G, Ho AJ, Kallupi M, Pokhrel N, Li HR, Chitre AS, Munro D, Mohammadi P, Carrette LLG, George O, Palmer AA, McVicker G, Telese F. Author Correction: Single-nucleus genomics in outbred rats with divergent cocaine addiction-like behaviors reveals changes in amygdala GABAergic inhibition. Nature Neuroscience. PMID 37845545 DOI: 10.1038/s41593-023-01489-z |
0.819 |
|
| 2023 |
Zhou JL, de Guglielmo G, Ho AJ, Kallupi M, Pokhrel N, Li HR, Chitre AS, Munro D, Mohammadi P, Carrette LLG, George O, Palmer AA, McVicker G, Telese F. Single-nucleus genomics in outbred rats with divergent cocaine addiction-like behaviors reveals changes in amygdala GABAergic inhibition. Nature Neuroscience. PMID 37798411 DOI: 10.1038/s41593-023-01452-y |
0.822 |
|
| 2023 |
Dulchavsky M, Mitra R, Wu K, Li J, Boer K, Liu X, Zhang Z, Vasquez C, Clark CT, Funckes K, Shankar K, Bonnet-Zahedi S, Siddiq M, Sepulveda Y, Suhandynata RT, ... ... George O, et al. Directed evolution unlocks oxygen reactivity for a nicotine-degrading flavoenzyme. Nature Chemical Biology. PMID 37770699 DOI: 10.1038/s41589-023-01426-y |
0.787 |
|
| 2023 |
Beldjoud H, Avelar A, de Guglielmo G, Kallupi M, Sedighim S, Velarde N, Boomhower B, Rizo N, Carrette LLG, George O. Chronic administration of a norepinephrine antagonist prevents and partially reverses escalation of cocaine self-administration. Addiction Biology. 28: e13316. PMID 37644893 DOI: 10.1111/adb.13316 |
0.805 |
|
| 2023 |
Meckel KR, Simpson SS, Godino A, Peck EG, Sens JP, Leonard MZ, George O, Calipari ES, Hofford RS, Kiraly DD. Microbial short-chain fatty acids regulate drug seeking and transcriptional control in a model of cocaine seeking. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 37528220 DOI: 10.1038/s41386-023-01661-w |
0.65 |
|
| 2023 |
Cheng Y, Dempsey RE, Roodsari SK, Shuboni-Mulligan DD, George O, Sanford LD, Guo ML. Cocaine Regulates NLRP3 Inflammasome Activity and CRF Signaling in a Region- and Sex-Dependent Manner in Rat Brain. Biomedicines. 11. PMID 37509440 DOI: 10.3390/biomedicines11071800 |
0.306 |
|
| 2023 |
Doyle MR, Martinez AR, Qiao R, Dirik S, Di Ottavio F, Pascasio G, Martin-Fardon R, Benner C, George O, Telese F, de Guglielmo G. Strain and sex-related behavioral variability of oxycodone dependence in rats. Neuropharmacology. 109635. PMID 37327971 DOI: 10.1016/j.neuropharm.2023.109635 |
0.679 |
|
| 2023 |
Carrette LLG, Kimbrough A, Davoudian PA, Kwan AC, Collazo A, George O. Hyperconnectivity of two separate long-range cholinergic systems contributes to the reorganization of the brain functional connectivity during nicotine withdrawal in male mice. Eneuro. PMID 37295945 DOI: 10.1523/ENEURO.0019-23.2023 |
0.807 |
|
| 2023 |
Kumaresan V, Lim Y, Juneja P, Tipton AE, de Guglielmo G, Carrette LLG, Kallupi M, Maturin L, Liu Y, George O, Zhang H. Abstinence from Escalation of Cocaine Intake Changes the microRNA Landscape in the Cortico-Accumbal Pathway. Biomedicines. 11. PMID 37239038 DOI: 10.3390/biomedicines11051368 |
0.782 |
|
| 2023 |
Carrette LLG, Kimbrough A, Davoudian PA, Kwan AC, Collazo A, George O. Hyperconnectivity of two separate long-range cholinergic systems contributes to the reorganization of the brain functional connectivity during nicotine withdrawal in male mice. Biorxiv : the Preprint Server For Biology. PMID 37034602 DOI: 10.1101/2023.03.29.534836 |
0.806 |
|
| 2023 |
Gabriel RA, Harjai B, Simpson S, Du AL, Tully JL, George O, Waterman R. An Ensemble Learning Approach to Improving Prediction of Case Duration for Spine Surgery: Algorithm Development and Validation. Jmir Perioperative Medicine. 6: e39650. PMID 36701181 DOI: 10.2196/39650 |
0.488 |
|
| 2022 |
de Guglielmo G, Simpson S, Kimbrough A, Conlisk D, Baker R, Cantor M, Kallupi M, George O. Voluntary and forced exposure to ethanol vapor produces similar escalation of alcohol drinking but differential recruitment of brain regions related to stress, habit, and reward in male rats. Neuropharmacology. 222: 109309. PMID 36334765 DOI: 10.1016/j.neuropharm.2022.109309 |
0.808 |
|
| 2022 |
George O, Ahmed SH, Gilpin NW. Are we compulsively chasing rainbows? Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 35982236 DOI: 10.1038/s41386-022-01419-w |
0.697 |
|
| 2022 |
Aldridge GM, Zarin TA, Brandner AJ, George O, Gilpin NW, Repunte-Canonigo V, Sanna PP, Koob GF, Vendruscolo LF, Schmeichel BE. Effects of single and dual hypocretin-receptor blockade or knockdown of hypocretin projections to the central amygdala on alcohol drinking in dependent male rats. Addiction Neuroscience. 3. PMID 35965958 DOI: 10.1016/j.addicn.2022.100028 |
0.711 |
|
| 2022 |
Duttke SH, Montilla-Perez P, Chang MW, Li H, Chen H, Carrette LLG, de Guglielmo G, George O, Palmer AA, Benner C, Telese F. Glucocorticoid Receptor-Regulated Enhancers Play a Central Role in the Gene Regulatory Networks Underlying Drug Addiction. Frontiers in Neuroscience. 16: 858427. PMID 35651629 DOI: 10.3389/fnins.2022.858427 |
0.815 |
|
| 2022 |
Carrette LLG, Corral C, Boomhower B, Brennan M, Crook C, Ortez C, Shankar K, Simpson S, Maturin L, Solberg Woods LC, Palmer AA, de Guglielmo G, George O. Leptin Protects Against the Development and Expression of Cocaine Addiction-Like Behavior in Heterogeneous Stock Rats. Frontiers in Behavioral Neuroscience. 16: 832899. PMID 35316955 DOI: 10.3389/fnbeh.2022.832899 |
0.802 |
|
| 2022 |
Shankar K, Ambroggi F, George O. Microstructural meal pattern analysis reveals a paradoxical acute increase in food intake after nicotine despite its long-term anorexigenic effects. Psychopharmacology. PMID 35129671 DOI: 10.1007/s00213-022-06071-2 |
0.804 |
|
| 2021 |
Grieder TE, Yee M, Vargas-Perez H, Maal-Bared G, George S, Ting-A-Kee R, George O, van der Kooy D. Administration of BDNF in the ventral tegmental area produces a switch from a nicotine-non-dependent D1R-mediated motivational state to a nicotine-dependent-like D2R-mediated motivational state. The European Journal of Neuroscience. PMID 34963197 DOI: 10.1111/ejn.15579 |
0.81 |
|
| 2021 |
Kallupi M, Kononoff J, Melas PA, Qvist JS, de Guglielmo G, Kandel ER, George O. Deep brain stimulation of the nucleus accumbens shell attenuates cocaine withdrawal but increases cocaine self-administration, cocaine-induced locomotor activity, and GluR1/GluA1 in the central nucleus of the amygdala in male cocaine-dependent rats. Brain Stimulation. 15: 13-22. PMID 34742997 DOI: 10.1016/j.brs.2021.11.003 |
0.815 |
|
| 2021 |
Simpson S, Mclellan R, Wellmeyer E, Matalon F, George O. Drugs and Bugs: The Gut-Brain Axis and Substance Use Disorders. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. PMID 34694571 DOI: 10.1007/s11481-021-10022-7 |
0.591 |
|
| 2021 |
Avelar AJ, George O. How nicotine withdrawal symptoms fight each other: interpeduncular GABA neuron activity dynamically controls negative affect vs. coping behavior. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 34593977 DOI: 10.1038/s41386-021-01185-1 |
0.788 |
|
| 2021 |
Kimbrough A, Kallupi M, Smith LC, Simpson S, Collazo A, George O. Characterization of the brain functional architecture of psychostimulant withdrawal using single-cell whole brain imaging. Eneuro. PMID 34580158 DOI: 10.1523/ENEURO.0208-19.2021 |
0.805 |
|
| 2021 |
Sedighim S, Carrette LL, Venniro M, Shaham Y, de Guglielmo G, George O. Individual differences in addiction-like behaviors and choice between cocaine versus food in Heterogeneous Stock rats. Psychopharmacology. PMID 34415376 DOI: 10.1007/s00213-021-05961-1 |
0.821 |
|
| 2021 |
Simpson S, Chen Y, Wellmeyer E, Smith LC, Aragon Montes B, George O, Kimbrough A. The Hidden Brain: Uncovering Previously Overlooked Brain Regions by Employing Novel Preclinical Unbiased Network Approaches. Frontiers in Systems Neuroscience. 15: 595507. PMID 33967705 DOI: 10.3389/fnsys.2021.595507 |
0.775 |
|
| 2021 |
Smith LC, Tieu L, Suhandynata RT, Boomhower B, Hoffman M, Sepulveda Y, Carrette LLG, Momper JD, Fitzgerald RL, Hanham K, Dowling J, Kallupi M, George O. Cannabidiol reduces withdrawal symptoms in nicotine-dependent rats. Psychopharmacology. PMID 33909102 DOI: 10.1007/s00213-021-05845-4 |
0.821 |
|
| 2021 |
Carrette LL, de Guglielmo G, Kallupi M, Maturin L, Brennan M, Boomhower B, Conlisk D, Sedighim S, Tieu L, Fannon MJ, Velarde N, Kononoff J, Kimbrough A, Simpson S, Smith LC, ... ... George O, et al. The cocaine and oxycodone biobanks, two repositories from genetically diverse and behaviorally characterized rats for the study of addiction. Eneuro. PMID 33875455 DOI: 10.1523/ENEURO.0033-21.2021 |
0.775 |
|
| 2021 |
McGinn MA, Tunstall BJ, Schlosburg JE, Gregory-Flores A, George O, de Guglielmo G, Mason BJ, Hunt HJ, Koob GF, Vendruscolo LF. Glucocorticoid receptor modulators decrease alcohol self-administration in male rats. Neuropharmacology. 108510. PMID 33647278 DOI: 10.1016/j.neuropharm.2021.108510 |
0.807 |
|
| 2020 |
Smith LC, George O. Advances in smoking cessation pharmacotherapy: Non-nicotinic approaches in animal models. Neuropharmacology. 108225. PMID 32758566 DOI: 10.1016/J.Neuropharm.2020.108225 |
0.568 |
|
| 2020 |
Smith LC, Kallupi M, Tieu L, Shankar K, Jaquish A, Barr J, Su Y, Velarde N, Sedighim S, Carrette LLG, Klodnicki M, Sun X, de Guglielmo G, George O. Validation of a nicotine vapor self-administration model in rats with relevance to electronic cigarette use. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 32544927 DOI: 10.1038/S41386-020-0734-8 |
0.814 |
|
| 2020 |
Simpson S, Kimbrough A, Boomhower B, McLellan R, Hughes M, Shankar K, de Guglielmo G, George O. Depletion of the Microbiome Alters the Recruitment of Neuronal Ensembles of Oxycodone Intoxication and Withdrawal. Eneuro. PMID 32341122 DOI: 10.1523/ENEURO.0312-19.2020 |
0.796 |
|
| 2020 |
Simpson S, Shankar K, Kimbrough A, George O. Role of Corticotropin-Releasing Factor in Alcohol and Nicotine Addiction. Brain Research. 146850. PMID 32330519 DOI: 10.1016/J.Brainres.2020.146850 |
0.82 |
|
| 2020 |
Kimbrough A, Kononoff J, Simpson S, Kallupi M, Sedighim S, Palomino K, Conlisk D, Momper JD, de Guglielmo G, George O. Oxycodone self-administration and withdrawal behaviors in male and female Wistar rats. Psychopharmacology. PMID 32114633 DOI: 10.1007/S00213-020-05479-Y |
0.793 |
|
| 2020 |
Lee CH, George O, Kimbrough A. Chronic voluntary caffeine intake in male Wistar rats reveals individual differences in addiction-like behavior. Pharmacology, Biochemistry, and Behavior. 172880. PMID 32105663 DOI: 10.1016/J.Pbb.2020.172880 |
0.751 |
|
| 2020 |
Kimbrough A, Lurie DJ, Collazo A, Kreifeldt M, Sidhu H, Macedo GC, D'Esposito M, Contet C, George O. Brain-wide functional architecture remodeling by alcohol dependence and abstinence. Proceedings of the National Academy of Sciences of the United States of America. PMID 31937658 DOI: 10.1073/Pnas.1909915117 |
0.798 |
|
| 2020 |
Kallupi M, Carrette LLG, Kononoff J, Solberg Woods LC, Palmer AA, Schweitzer P, George O, de Guglielmo G. Nociceptin attenuates the escalation of oxycodone self-administration by normalizing CeA-GABA transmission in highly addicted rats. Proceedings of the National Academy of Sciences of the United States of America. PMID 31932450 DOI: 10.1073/Pnas.1915143117 |
0.811 |
|
| 2019 |
de Guglielmo G, Kallupi M, Sedighim S, Newman AH, George O. Dopamine D Receptor Antagonism Reverses the Escalation of Oxycodone Self-administration and Decreases Withdrawal-Induced Hyperalgesia and Irritability-Like Behavior in Oxycodone-Dependent Heterogeneous Stock Rats. Frontiers in Behavioral Neuroscience. 13: 292. PMID 31992976 DOI: 10.3389/Fnbeh.2019.00292 |
0.81 |
|
| 2019 |
de Guglielmo G, Fu Y, Chen J, Larrosa E, Hoang I, Kawamura T, Lorrai I, Zorman B, Bryant J, George O, Sumazin P, Lefebvre C, Repunte-Canonigo V, Paolo Sanna P. Increases in compulsivity, inflammation, and neural injury in HIV transgenic rats with escalated methamphetamine self-administration under extended-access conditions. Brain Research. 146502. PMID 31605699 DOI: 10.1016/J.Brainres.2019.146502 |
0.694 |
|
| 2019 |
Spierling S, de Guglielmo G, Kirson D, Kreisler A, Roberto M, George O, Zorrilla EP. Insula to ventral striatal projections mediate compulsive eating produced by intermittent access to palatable food. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 31593982 DOI: 10.1038/S41386-019-0538-X |
0.804 |
|
| 2019 |
Kallupi M, de Guglielmo G, Larrosa E, George O. Exposure to passive nicotine vapor in male adolescent rats produces a withdrawal-like state and facilitates nicotine self-administration during adulthood. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. PMID 31462388 DOI: 10.1016/J.Euroneuro.2019.08.299 |
0.804 |
|
| 2019 |
Goulding SP, de Guglielmo G, Carrette LLG, George O, Contet C. Systemic administration of the cyclin-dependent kinase inhibitor (S)-CR8 selectively reduces escalated ethanol intake in dependent rats. Alcoholism, Clinical and Experimental Research. PMID 31403700 DOI: 10.1111/Acer.14177 |
0.798 |
|
| 2019 |
de Guglielmo G, Kallupi M, Pomrenze MB, Crawford E, Simpson S, Schweitzer P, Koob GF, Messing RO, George O. Inactivation of a CRF-dependent amygdalofugal pathway reverses addiction-like behaviors in alcohol-dependent rats. Nature Communications. 10: 1238. PMID 30886240 DOI: 10.1038/S41467-019-09183-0 |
0.811 |
|
| 2018 |
Kallupi M, Xue S, Zhou B, Janda KD, George O. An enzymatic approach reverses nicotine dependence, decreases compulsive-like intake, and prevents relapse. Science Advances. 4: eaat4751. PMID 30345354 DOI: 10.1126/Sciadv.Aat4751 |
0.712 |
|
| 2018 |
Kononoff J, Melas PA, Kallupi M, de Guglielmo G, Kimbrough A, Scherma M, Fadda P, Kandel DB, Kandel ER, George O. Adolescent cannabinoid exposure induces irritability-like behavior and cocaine cross-sensitization without affecting the escalation of cocaine self-administration in adulthood. Scientific Reports. 8: 13893. PMID 30224774 DOI: 10.1038/S41598-018-31921-5 |
0.817 |
|
| 2018 |
Keller JA, Chen J, Simpson S, Wang EH, Lilascharoen V, George O, Lim BK, Stowers L. Voluntary urination control by brainstem neurons that relax the urethral sphincter. Nature Neuroscience. PMID 30104734 DOI: 10.1038/S41593-018-0204-3 |
0.584 |
|
| 2018 |
Kononoff J, Kallupi M, Kimbrough A, Conlisk D, de Guglielmo G, George O. Systemic and Intra-Habenular Activation of the Orphan G Protein-Coupled Receptor GPR139 Decreases Compulsive-Like Alcohol Drinking and Hyperalgesia in Alcohol-Dependent Rats. Eneuro. 5. PMID 29971251 DOI: 10.1523/ENEURO.0153-18.2018 |
0.81 |
|
| 2018 |
Pelloux Y, Degoulet M, Tiran-Cappello A, Cohen C, Lardeux S, George O, Koob GF, Ahmed SH, Baunez C. Subthalamic nucleus high frequency stimulation prevents and reverses escalated cocaine use. Molecular Psychiatry. PMID 29880881 DOI: 10.1038/S41380-018-0080-Y |
0.759 |
|
| 2018 |
de Guglielmo G, Conlisk DE, Barkley-Levenson AM, Palmer AA, George O. Inhibition of Glyoxalase 1 reduces alcohol self-administration in dependent and nondependent rats. Pharmacology, Biochemistry, and Behavior. PMID 29505808 DOI: 10.1016/J.Pbb.2018.03.001 |
0.811 |
|
| 2018 |
Rupprecht LE, Kreisler AD, Spierling SR, de Guglielmo G, Kallupi M, George O, Donny EC, Zorrilla EP, Sved AF. Self-administered nicotine increases fat metabolism and suppresses weight gain in male rats. Psychopharmacology. PMID 29354872 DOI: 10.1007/S00213-018-4830-Y |
0.807 |
|
| 2018 |
Xue S, Kallupi M, Zhou B, Smith LC, Miranda PO, George O, Janda KD. An enzymatic advance in nicotine cessation therapy. Chemical Communications (Cambridge, England). PMID 29308799 DOI: 10.1039/C7Cc09134F |
0.73 |
|
| 2017 |
Verheij MMM, Contet C, Karel P, Latour J, van der Doelen RHA, Geenen B, van Hulten JA, Meyer F, Kozicz T, George O, Koob GF, Homberg JR. Median and Dorsal Raphe Serotonergic Neurons Control Moderate Versus Compulsive Cocaine Intake. Biological Psychiatry. PMID 29357981 DOI: 10.1016/J.Biopsych.2017.10.031 |
0.776 |
|
| 2017 |
George O, Koob GF. Individual differences in the neuropsychopathology of addiction. Dialogues in Clinical Neuroscience. 19: 217-229. PMID 29302219 |
0.554 |
|
| 2017 |
Matzeu A, Kallupi M, George O, Schweitzer P, Martin-Fardon R. Dynorphin Counteracts Orexin in the Paraventricular Nucleus of the Thalamus: Cellular and Behavioral Evidence. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 29052613 DOI: 10.1038/Npp.2017.250 |
0.734 |
|
| 2017 |
Kimbrough A, de Guglielmo G, Kononoff J, Kallupi M, Zorrilla EP, George O. CRF1 receptor-dependent increases in irritability-like behavior during abstinence from chronic intermittent ethanol vapor exposure. Alcoholism, Clinical and Experimental Research. PMID 28833238 DOI: 10.1111/Acer.13484 |
0.792 |
|
| 2017 |
Vendruscolo JC, Tunstall BJ, Carmack SA, Schmeichel BE, Lowery-Gionta EG, Cole M, George O, Vandewater S, Taffe M, Koob GF, Vendruscolo LF. Compulsive-Like Sufentanil Vapor Self-Administration in the Rat. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 28812595 DOI: 10.1038/Npp.2017.172 |
0.791 |
|
| 2017 |
Kimbrough A, Kim S, Cole M, Brennan M, George O. Intermittent Access to Ethanol Drinking Facilitates the Transition to Excessive Drinking After Chronic Intermittent Ethanol Vapor Exposure. Alcoholism, Clinical and Experimental Research. PMID 28679148 DOI: 10.1111/Acer.13434 |
0.794 |
|
| 2017 |
Kallupi M, George O. Nicotine Vapor Method to Induce Nicotine Dependence in Rodents. Current Protocols in Neuroscience. 80: 8.41.1-8.41.10. PMID 28678400 DOI: 10.1002/Cpns.34 |
0.682 |
|
| 2017 |
de Guglielmo G, Matzeu A, Kononoff J, Mattioni J, Martin-Fardon R, George O. Cebranopadol blocks the escalation of cocaine intake and conditioned reinstatement of cocaine seeking in rats. The Journal of Pharmacology and Experimental Therapeutics. PMID 28645915 DOI: 10.1124/Jpet.117.241042 |
0.823 |
|
| 2017 |
Grieder TE, George O, Yee M, Bergamini MA, Chwalek M, Maal-Bared G, Vargas-Perez H, van der Kooy D. Deletion of α5 nicotine receptor subunits abolishes nicotinic aversive motivational effects in a manner that phenocopies dopamine receptor antagonism. The European Journal of Neuroscience. PMID 28498560 DOI: 10.1111/Ejn.13605 |
0.804 |
|
| 2017 |
George O, Hope BT. Cortical and amygdalar neuronal ensembles in alcohol seeking, drinking and withdrawal. Neuropharmacology. PMID 28435008 DOI: 10.1016/J.Neuropharm.2017.04.031 |
0.395 |
|
| 2017 |
Varodayan FP, de Guglielmo G, Logrip ML, George O, Roberto M. Alcohol dependence disrupts amygdalar L-type voltage-gated calcium channel mechanisms. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 28363981 DOI: 10.1523/Jneurosci.3721-16.2017 |
0.74 |
|
| 2017 |
de Guglielmo G, Kallupi M, Cole MD, George O. Voluntary induction and maintenance of alcohol dependence in rats using alcohol vapor self-administration. Psychopharmacology. PMID 28342089 DOI: 10.1007/S00213-017-4608-7 |
0.811 |
|
| 2017 |
de Guglielmo G, Kallupi M, Crawford E, Koob GF, Messing RO, George O. Optogenetic characterization of CeA CRF pathways in alcohol dependence Alcohol. 60: 235. DOI: 10.1016/J.Alcohol.2017.02.319 |
0.738 |
|
| 2017 |
George O. Chemogenetic and optogenetic control of excessive alcohol drinking through inactivation of a neuronal ensemble in the central nucleus of the amygdala Alcohol. 60: 214. DOI: 10.1016/J.Alcohol.2017.02.232 |
0.319 |
|
| 2017 |
Messing RO, Pomrenze MB, de Guglielmo G, Kallupi M, Koob GF, George O. A distributed CRF network in rat extended amygdala regulates anxiety and excessive alcohol drinking Alcohol. 60: 212. DOI: 10.1016/J.Alcohol.2017.02.221 |
0.744 |
|
| 2016 |
Harris RA, Bajo M, Bell RL, Blednov YA, Varodayan FP, Truitt J, de Guglielmo G, Lasek AW, Logrip ML, Vendruscolo LF, Roberts AJ, Roberts E, George O, Mayfield J, Billiar TR, et al. Genetic and pharmacologic manipulation of TLR4 has minimal impact on ethanol consumption in rodents. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 27986929 DOI: 10.1523/Jneurosci.2002-16.2016 |
0.8 |
|
| 2016 |
Wade CL, Kallupi M, Hernandez DO, Breysse E, de Guglielmo G, Crawford E, Koob GF, Schweitzer P, Baunez C, George O. High-Frequency Stimulation of the Subthalamic Nucleus Blocks Compulsive-Like Re-Escalation of Heroin Taking in Rats. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 27917870 DOI: 10.1038/Npp.2016.270 |
0.817 |
|
| 2016 |
de Guglielmo G, Crawford E, Kim S, Vendruscolo LF, Hope BT, Brennan M, Cole M, Koob GF, George O. Recruitment of a Neuronal Ensemble in the Central Nucleus of the Amygdala Is Required for Alcohol Dependence. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 9446-53. PMID 27605618 DOI: 10.1523/Jneurosci.1395-16.2016 |
0.795 |
|
| 2015 |
Pomrenze MB, Millan EZ, Hopf FW, Keiflin R, Maiya R, Blasio A, Dadgar J, Kharazia V, De Guglielmo G, Crawford E, Janak PH, George O, Rice KC, Messing RO. A Transgenic Rat for Investigating the Anatomy and Function of Corticotrophin Releasing Factor Circuits. Frontiers in Neuroscience. 9: 487. PMID 26733798 DOI: 10.3389/Fnins.2015.00487 |
0.655 |
|
| 2015 |
Vendruscolo LF, Estey D, Goodell V, Macshane LG, Logrip ML, Schlosburg JE, McGinn MA, Zamora-Martinez ER, Belanoff JK, Hunt HJ, Sanna PP, George O, Koob GF, Edwards S, Mason BJ. Glucocorticoid receptor antagonism decreases alcohol seeking in alcohol-dependent individuals. The Journal of Clinical Investigation. PMID 26121746 DOI: 10.1172/Jci79828 |
0.794 |
|
| 2015 |
Zhao-Shea R, DeGroot SR, Liu L, Vallaster M, Pang X, Su Q, Gao G, Rando OJ, Martin GE, George O, Gardner PD, Tapper AR. Increased CRF signalling in a ventral tegmental area-interpeduncular nucleus-medial habenula circuit induces anxiety during nicotine withdrawal. Nature Communications. 6: 6770. PMID 25898242 DOI: 10.1038/Ncomms7770 |
0.379 |
|
| 2015 |
Leão RM, Cruz FC, Vendruscolo LF, de Guglielmo G, Logrip ML, Planeta CS, Hope BT, Koob GF, George O. Chronic nicotine activates stress/reward-related brain regions and facilitates the transition to compulsive alcohol drinking. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 6241-53. PMID 25878294 DOI: 10.1523/Jneurosci.3302-14.2015 |
0.784 |
|
| 2015 |
Whitfield TW, Schlosburg JE, Wee S, Gould A, George O, Grant Y, Zamora-Martinez ER, Edwards S, Crawford E, Vendruscolo LF, Koob GF. κ Opioid receptors in the nucleus accumbens shell mediate escalation of methamphetamine intake. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 4296-305. PMID 25762676 DOI: 10.1523/Jneurosci.1978-13.2015 |
0.817 |
|
| 2015 |
Cohen A, Soleiman MT, Talia R, Koob GF, George O, Mandyam CD. Extended access nicotine self-administration with periodic deprivation increases immature neurons in the hippocampus. Psychopharmacology. 232: 453-63. PMID 25059540 DOI: 10.1007/S00213-014-3685-0 |
0.697 |
|
| 2015 |
Cohen A, Treweek J, Edwards S, Leão RM, Schulteis G, Koob GF, George O. Extended access to nicotine leads to a CRF1 receptor dependent increase in anxiety-like behavior and hyperalgesia in rats. Addiction Biology. 20: 56-68. PMID 23869743 DOI: 10.1111/Adb.12077 |
0.778 |
|
| 2014 |
Grieder TE, Herman MA, Contet C, Tan LA, Vargas-Perez H, Cohen A, Chwalek M, Maal-Bared G, Freiling J, Schlosburg JE, Clarke L, Crawford E, Koebel P, Repunte-Canonigo V, Sanna PP, ... ... George O, et al. VTA CRF neurons mediate the aversive effects of nicotine withdrawal and promote intake escalation. Nature Neuroscience. 17: 1751-8. PMID 25402857 DOI: 10.1038/Nn.3872 |
0.806 |
|
| 2014 |
Repunte-Canonigo V, Lefebvre C, George O, Kawamura T, Morales M, Koob GF, Califano A, Masliah E, Sanna PP. Gene expression changes consistent with neuroAIDS and impaired working memory in HIV-1 transgenic rats. Molecular Neurodegeneration. 9: 26. PMID 24980976 DOI: 10.1186/1750-1326-9-26 |
0.518 |
|
| 2014 |
George O, Koob GF, Vendruscolo LF. Negative reinforcement via motivational withdrawal is the driving force behind the transition to addiction. Psychopharmacology. 231: 3911-7. PMID 24923982 DOI: 10.1007/S00213-014-3623-1 |
0.542 |
|
| 2014 |
Buck CL, Malavar JC, George O, Koob GF, Vendruscolo LF. Anticipatory 50 kHz ultrasonic vocalizations are associated with escalated alcohol intake in dependent rats. Behavioural Brain Research. 271: 171-6. PMID 24914463 DOI: 10.1016/J.Bbr.2014.06.003 |
0.617 |
|
| 2014 |
Cohen A, Whitfield TW, Kreifeldt M, Koebel P, Kieffer BL, Contet C, George O, Koob GF. Virus-mediated shRNA knockdown of prodynorphin in the rat nucleus accumbens attenuates depression-like behavior and cocaine locomotor sensitization. Plos One. 9: e97216. PMID 24816773 DOI: 10.1371/Journal.Pone.0097216 |
0.821 |
|
| 2014 |
Buck CL, Vendruscolo LF, Koob GF, George O. Dopamine D1 and μ-opioid receptor antagonism blocks anticipatory 50 kHz ultrasonic vocalizations induced by palatable food cues in Wistar rats. Psychopharmacology. 231: 929-37. PMID 24221826 DOI: 10.1007/S00213-013-3307-2 |
0.601 |
|
| 2014 |
Koob GF, Buck CL, Cohen A, Edwards S, Park PE, Schlosburg JE, Schmeichel B, Vendruscolo LF, Wade CL, Whitfield TW, George O. Addiction as a stress surfeit disorder. Neuropharmacology. 76: 370-82. PMID 23747571 DOI: 10.1016/J.Neuropharm.2013.05.024 |
0.809 |
|
| 2014 |
Kallupi M, Vendruscolo LF, Carmichael CY, George O, Koob GF, Gilpin NW. Neuropeptide YY(2)R blockade in the central amygdala reduces anxiety-like behavior but not alcohol drinking in alcohol-dependent rats. Addiction Biology. 19: 755-7. PMID 23639035 DOI: 10.1111/Adb.12059 |
0.805 |
|
| 2014 |
Deschaux O, Vendruscolo LF, Schlosburg JE, Diaz-Aguilar L, Yuan CJ, Sobieraj JC, George O, Koob GF, Mandyam CD. Hippocampal neurogenesis protects against cocaine-primed relapse. Addiction Biology. 19: 562-74. PMID 23278919 DOI: 10.1111/Adb.12019 |
0.792 |
|
| 2014 |
Gilpin NW, Whitaker AM, Baynes B, Abdel AY, Weil MT, George O. Nicotine vapor inhalation escalates nicotine self-administration. Addiction Biology. 19: 587-92. PMID 23240929 DOI: 10.1111/Adb.12021 |
0.668 |
|
| 2013 |
Schlosburg JE, Whitfield TW, Park PE, Crawford EF, George O, Vendruscolo LF, Koob GF. Long-term antagonism of κ opioid receptors prevents escalation of and increased motivation for heroin intake. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 19384-92. PMID 24305833 DOI: 10.1523/Jneurosci.1979-13.2013 |
0.786 |
|
| 2013 |
Cohen A, George O. Animal models of nicotine exposure: relevance to second-hand smoking, electronic cigarette use, and compulsive smoking. Frontiers in Psychiatry. 4: 41. PMID 23761766 DOI: 10.3389/Fpsyt.2013.00041 |
0.574 |
|
| 2013 |
George O, Koob GF. Control of craving by the prefrontal cortex. Proceedings of the National Academy of Sciences of the United States of America. 110: 4165-6. PMID 23483010 DOI: 10.1073/Pnas.1301245110 |
0.562 |
|
| 2012 |
George O, Sanders C, Freiling J, Grigoryan E, Vu S, Allen CD, Crawford E, Mandyam CD, Koob GF. Recruitment of medial prefrontal cortex neurons during alcohol withdrawal predicts cognitive impairment and excessive alcohol drinking. Proceedings of the National Academy of Sciences of the United States of America. 109: 18156-61. PMID 23071333 DOI: 10.1073/Pnas.1116523109 |
0.603 |
|
| 2012 |
Cohen A, Koob GF, George O. Robust escalation of nicotine intake with extended access to nicotine self-administration and intermittent periods of abstinence. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 37: 2153-60. PMID 22549121 DOI: 10.1038/Npp.2012.67 |
0.699 |
|
| 2012 |
Tobey KM, Walentiny DM, Wiley JL, Carroll FI, Damaj MI, Azar MR, Koob GF, George O, Harris LS, Vann RE. Effects of the specific α4β2 nAChR antagonist, 2-fluoro-3-(4-nitrophenyl) deschloroepibatidine, on nicotine reward-related behaviors in rats and mice. Psychopharmacology. 223: 159-68. PMID 22526534 DOI: 10.1007/S00213-012-2703-3 |
0.626 |
|
| 2012 |
Goeders NE, Cohen A, Fox BS, Azar MR, George O, Koob GF. Effects of the combination of metyrapone and oxazepam on intravenous nicotine self-administration in rats. Psychopharmacology. 223: 17-25. PMID 22418732 DOI: 10.1007/S00213-012-2682-4 |
0.691 |
|
| 2012 |
Grieder TE, George O, Tan H, George SR, Le Foll B, Laviolette SR, van der Kooy D. Phasic D1 and tonic D2 dopamine receptor signaling double dissociate the motivational effects of acute nicotine and chronic nicotine withdrawal. Proceedings of the National Academy of Sciences of the United States of America. 109: 3101-6. PMID 22308372 DOI: 10.1073/Pnas.1114422109 |
0.812 |
|
| 2012 |
Recinto P, Samant AR, Chavez G, Kim A, Yuan CJ, Soleiman M, Grant Y, Edwards S, Wee S, Koob GF, George O, Mandyam CD. Levels of neural progenitors in the hippocampus predict memory impairment and relapse to drug seeking as a function of excessive methamphetamine self-administration. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 37: 1275-87. PMID 22205547 DOI: 10.1038/Npp.2011.315 |
0.704 |
|
| 2012 |
George O, Le Moal M, Koob GF. Allostasis and addiction: role of the dopamine and corticotropin-releasing factor systems. Physiology & Behavior. 106: 58-64. PMID 22108506 DOI: 10.1016/J.Physbeh.2011.11.004 |
0.722 |
|
| 2011 |
George O, Koob GF. Craving, context and the cortex. Nature Neuroscience. 14: 409-10. PMID 21445066 DOI: 10.1038/Nn.2787 |
0.548 |
|
| 2011 |
George O, Lloyd A, Carroll FI, Damaj MI, Koob GF. Varenicline blocks nicotine intake in rats with extended access to nicotine self-administration. Psychopharmacology. 213: 715-22. PMID 20924754 DOI: 10.1007/S00213-010-2024-3 |
0.618 |
|
| 2010 |
George O, Koob GF. Individual differences in prefrontal cortex function and the transition from drug use to drug dependence. Neuroscience and Biobehavioral Reviews. 35: 232-47. PMID 20493211 DOI: 10.1016/J.Neubiorev.2010.05.002 |
0.578 |
|
| 2010 |
George O, Vallée M, Vitiello S, Le Moal M, Piazza PV, Mayo W. Low brain allopregnanolone levels mediate flattened circadian activity associated with memory impairments in aged rats. Biological Psychiatry. 68: 956-63. PMID 20471631 DOI: 10.1016/J.Biopsych.2010.03.022 |
0.779 |
|
| 2010 |
George O, Grieder TE, Cole M, Koob GF. Exposure to chronic intermittent nicotine vapor induces nicotine dependence. Pharmacology, Biochemistry, and Behavior. 96: 104-7. PMID 20420848 DOI: 10.1016/J.Pbb.2010.04.013 |
0.803 |
|
| 2009 |
Orio L, Edwards S, George O, Parsons LH, Koob GF. A role for the endocannabinoid system in the increased motivation for cocaine in extended-access conditions. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 4846-57. PMID 19369553 DOI: 10.1523/Jneurosci.0563-09.2009 |
0.831 |
|
| 2008 |
George O, Mandyam CD, Wee S, Koob GF. Extended access to cocaine self-administration produces long-lasting prefrontal cortex-dependent working memory impairments. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 33: 2474-82. PMID 18033234 DOI: 10.1038/Sj.Npp.1301626 |
0.602 |
|
| 2007 |
George O, Ghozland S, Azar MR, Cottone P, Zorrilla EP, Parsons LH, O'Dell LE, Richardson HN, Koob GF. CRF-CRF1 system activation mediates withdrawal-induced increases in nicotine self-administration in nicotine-dependent rats. Proceedings of the National Academy of Sciences of the United States of America. 104: 17198-203. PMID 17921249 DOI: 10.1073/Pnas.0707585104 |
0.817 |
|
| 2006 |
Lemaire V, Billard JM, Dutar P, George O, Piazza PV, Epelbaum J, Le Moal M, Mayo W. Motherhood-induced memory improvement persists across lifespan in rats but is abolished by a gestational stress. The European Journal of Neuroscience. 23: 3368-74. PMID 16820026 DOI: 10.1111/J.1460-9568.2006.04870.X |
0.779 |
|
| 2006 |
Rabat A, Bouyer JJ, George O, Le Moal M, Mayo W. Chronic exposure of rats to noise: relationship between long-term memory deficits and slow wave sleep disturbances. Behavioural Brain Research. 171: 303-12. PMID 16716416 DOI: 10.1016/J.Bbr.2006.04.007 |
0.743 |
|
| 2006 |
George O, Vallée M, Le Moal M, Mayo W. Neurosteroids and cholinergic systems: implications for sleep and cognitive processes and potential role of age-related changes. Psychopharmacology. 186: 402-13. PMID 16416333 DOI: 10.1007/S00213-005-0254-6 |
0.73 |
|
| 2006 |
George O, Parducz A, Dupret D, Kharouby M, Le Moal M, Piazza PV, Mayo W. Smad-dependent alterations of PPT cholinergic neurons as a pathophysiological mechanism of age-related sleep-dependent memory impairments. Neurobiology of Aging. 27: 1848-58. PMID 16316709 DOI: 10.1016/J.Neurobiolaging.2005.10.014 |
0.773 |
|
| 2004 |
Vallée M, George O, Vitiello S, Le Moal M, Mayo W. New insights into the role of neuroactive steroids in cognitive aging. Experimental Gerontology. 39: 1695-704. PMID 15582285 DOI: 10.1016/J.Exger.2004.07.012 |
0.732 |
|
| 2004 |
Darbra S, George O, Bouyer JJ, Piazza PV, Le Moal M, Mayo W. Sleep-wake states and cortical synchronization control by pregnenolone sulfate into the pedunculopontine nucleus. Journal of Neuroscience Research. 76: 742-7. PMID 15139033 DOI: 10.1002/Jnr.20074 |
0.765 |
|
| 2003 |
Mayo W, George O, Darbra S, Bouyer JJ, Vallée M, Darnaudéry M, Pallarès M, Lemaire-Mayo V, Le Moal M, Piazza PV, Abrous N. Individual differences in cognitive aging: implication of pregnenolone sulfate. Progress in Neurobiology. 71: 43-8. PMID 14611866 DOI: 10.1016/J.Pneurobio.2003.09.006 |
0.774 |
|
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