| Year |
Citation |
Score |
| 2024 |
Li K, McClenahan SJ, Han C, Bungard JD, Rathnayake U, Boutaud O, Bauer JA, Days E, Lindsley CW, Shelton EL, Denton JS. . Molecular Pharmacology. PMID 38302135 DOI: 10.1124/molpharm.123.000783 |
0.383 |
|
| 2023 |
Dodd CJ, Chronister KS, Rathnayake U, Parr LC, Li K, Chang S, Mi D, Days EL, Bauer JA, Cho HP, Boutaud O, Denton JS, Lindsley CW, Han C. Synthesis and SAR of a novel Kir6.2/SUR1 channel opener scaffold identified by HTS. Bioorganic & Medicinal Chemistry Letters. 87: 129256. PMID 36966977 DOI: 10.1016/j.bmcl.2023.129256 |
0.339 |
|
| 2023 |
Takahashi H, Yamada T, Denton JS, Strange K, Karakas E. Cryo-EM structures of a LRRC8 chimera with native functional properties reveal heptameric assembly. Elife. 12. PMID 36897307 DOI: 10.7554/eLife.82431 |
0.403 |
|
| 2023 |
Denton JS, Delpire E. Special collection on inward rectifying K channels. American Journal of Physiology. Cell Physiology. 324: C603-C605. PMID 36689674 DOI: 10.1152/ajpcell.00457.2022 |
0.356 |
|
| 2023 |
Lyon M, Li P, Ferreira JJ, Lazarenko RM, Kharade SV, Kramer M, McClenahan SJ, Days E, Bauer JA, Spitznagel BD, Weaver CD, Borrego Alvarez A, Puga Molina LC, Lybaert P, Khambekar S, ... ... Denton J, et al. A selective inhibitor of the sperm-specific potassium channel SLO3 impairs human sperm function. Proceedings of the National Academy of Sciences of the United States of America. 120: e2212338120. PMID 36649421 DOI: 10.1073/pnas.2212338120 |
0.305 |
|
| 2022 |
McClenahan SJ, Kent C, Kharade S, Isaeva E, Williams J, Han C, Terker A, Gresham R, Lazarenko R, Days E, Romaine I, Bauer J, Boutaud O, Sulikowski G, Harris R, ... ... Denton JS, et al. . Molecular Pharmacology. PMID 35246480 DOI: 10.1124/molpharm.121.000464 |
0.439 |
|
| 2022 |
Figueroa EE, Denton JS. A SWELL time to develop the molecular pharmacology of the volume-regulated anion channel (VRAC). Channels (Austin, Tex.). 16: 27-36. PMID 35114895 DOI: 10.1080/19336950.2022.2033511 |
0.384 |
|
| 2021 |
Isaeva E, Bohovyk R, Fedoriuk M, Shalygin A, Klemens CA, Zietara A, Levchenko V, Denton JS, Staruschenko A, Palygin O. Crosstalk between epithelial sodium channels (ENaC) and basolateral potassium channels (K 4.1/K 5.1) in the cortical collecting duct. British Journal of Pharmacology. PMID 34904226 DOI: 10.1111/bph.15779 |
0.361 |
|
| 2021 |
Piermarini PM, Denton JS, Swale DR. The Molecular Physiology and Toxicology of Inward Rectifier Potassium Channels in Insects. Annual Review of Entomology. PMID 34606365 DOI: 10.1146/annurev-ento-062121-063338 |
0.404 |
|
| 2021 |
Figueroa EE, Denton JS. Zinc pyrithione activates the volume-regulated anion channel through an antioxidant-sensitive mechanism. American Journal of Physiology. Cell Physiology. PMID 33826406 DOI: 10.1152/ajpcell.00070.2021 |
0.394 |
|
| 2021 |
Weaver CD, Denton JS. Next-generation inward rectifier potassium channel modulators: Discovery and molecular pharmacology. American Journal of Physiology. Cell Physiology. PMID 33826405 DOI: 10.1152/ajpcell.00548.2020 |
0.404 |
|
| 2020 |
Yamada T, Figueroa EE, Denton JS, Strange K. LRRC8A homohexameric channels poorly recapitulate VRAC regulation and pharmacology. American Journal of Physiology. Cell Physiology. PMID 33356947 DOI: 10.1152/ajpcell.00454.2020 |
0.448 |
|
| 2020 |
Spitznagel BD, Mishra NM, Qunies AM, Prael FJ, Du Y, Kozek KA, Lazarenko RM, Denton JS, Emmitte KA, Weaver CD. VU0606170, a Selective Slack Channels Inhibitor, Decreases Calcium Oscillations in Cultured Cortical Neurons. Acs Chemical Neuroscience. 11: 3658-3671. PMID 33143429 DOI: 10.1021/acschemneuro.0c00583 |
0.44 |
|
| 2020 |
Aretz C, Kharade SV, Chronister K, Trigueros RR, Rodriguez EM, Piermarini PM, Denton JS, Hopkins CR. Further SAR on the (phenylsulfonyl)piperazine scaffold as inhibitors of the Aedes aegypti Kir1 (AeKir) channel and larvicides. Chemmedchem. PMID 32926544 DOI: 10.1002/Cmdc.202000598 |
0.462 |
|
| 2020 |
Zaborska KE, Dadi PK, Dickerson MT, Nakhe AY, Thorson AS, Schaub CM, Graff SM, Stanley JE, Kondapavuluru RS, Denton JS, Jacobson DA. Lactate activation of α-cell K channels inhibits glucagon secretion by hyperpolarizing the membrane potential and reducing Ca entry. Molecular Metabolism. 101056. PMID 32736089 DOI: 10.1016/J.Molmet.2020.101056 |
0.34 |
|
| 2020 |
Nakhe AY, Dadi P, Westover D, Days E, Denton J, Jacobson D. 2075-P: Testing the First Selective Talk-1 Inhibitors for Their Ability to Improve ß-Cell Function in Diabetes Diabetes. 69. DOI: 10.2337/Db20-2075-P |
0.398 |
|
| 2020 |
McClenahan SJ, Kharade SV, Denton JS. Development of novel therapeutics for treating edema and SeSAME/EAST syndrome targeting heteromeric Kir4.1/5.1 potassium channels The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.06158 |
0.45 |
|
| 2020 |
Isaeva E, Palygin O, Shalygin A, Bohovyk R, Fedoriuk M, Klemens C, El-Meanawy A, Denton J, Staruschenko A. Contribution of K
ir
4.1/K
ir
5.1 Channels to the Control of ENaC‐Mediated Apical Sodium Transport in the Cortical Collecting Duct The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.02233 |
0.382 |
|
| 2020 |
Figueroa EE, Denton JS. Development of Small-Molecule Inhibitors of Proton-Activated Chloride Channels Biophysical Journal. 118: 590a. DOI: 10.1016/J.Bpj.2019.11.3197 |
0.476 |
|
| 2020 |
Yamada T, Denton JS, Strange K. Functional and Pore Properties of the LRRC8A Homomeric Channel are Distinct from Those of LRRC8 Chimeras and Heteromres Biophysical Journal. 118: 418a. DOI: 10.1016/J.Bpj.2019.11.2359 |
0.471 |
|
| 2019 |
Afzal A, Figueroa EE, Kharade SV, Bittman K, Matlock BK, Flaherty DK, Denton JS. The LRRC8 volume-regulated anion channel inhibitor, DCPIB, inhibits mitochondrial respiration independently of the channel. Physiological Reports. 7: e14303. PMID 31814333 DOI: 10.14814/Phy2.14303 |
0.46 |
|
| 2019 |
Figueroa EE, Kramer M, Strange K, Denton JS. CysLT1 receptor antagonists Pranlukast and Zafirlukast inhibit LRRC8-mediated volume regulated anion channels independently of the receptor. American Journal of Physiology. Cell Physiology. PMID 31390227 DOI: 10.1016/J.Bpj.2019.11.3186 |
0.443 |
|
| 2019 |
Kharade SV, Sanchez-Andres JV, Fulton MG, Shelton EJ, Blobaum AL, Engers DW, Hofmann CS, Dadi PK, Lantier L, Jacobson DA, Lindsley CW, Denton JS. Structure-activity relationships, pharmacokinetics, and pharmacodynamics of the Kir6.2/SUR1-specific channel opener, VU0071063. The Journal of Pharmacology and Experimental Therapeutics. PMID 31201216 DOI: 10.1124/Jpet.119.257204 |
0.492 |
|
| 2019 |
Iwaki Y, Yashiro K, Kokubo M, Mori T, Wieting JM, McGowan KM, Bridges TM, Engers DW, Denton JS, Kurata H, Lindsley CW. Towards a TREK-1/2 (TWIK-Related K+ Channel 1 and 2) dual activator tool compound: Multi-dimensional optimization of BL-1249. Bioorganic & Medicinal Chemistry Letters. PMID 31072652 DOI: 10.1016/J.Bmcl.2019.04.048 |
0.412 |
|
| 2019 |
Aretz C, Morwitzer MJ, Sanford A, Hogan AM, Portillo M, Kharade SV, Kramer M, Mcarthey J, Trigueros RR, Piermarini PM, Denton JS, Hopkins CR. Discovery and characterization of 2-nitro-5-(4-(phenylsulfonyl)piperazin-1-yl)-N-(pyridin-4-ylmethyl)anilines as novel inhibitors of the Aedes aegypti Kir1 (AeKir1) channel. Acs Infectious Diseases. PMID 30832472 DOI: 10.1021/Acsinfecdis.8B00368 |
0.468 |
|
| 2019 |
Strange K, Yamada T, Denton JS. A 30-year journey from volume-regulated anion currents to molecular structure of the LRRC8 channel. The Journal of General Physiology. 151: 100-117. PMID 30651298 DOI: 10.1085/Jgp.201812138 |
0.482 |
|
| 2018 |
Rusconi Trigueros R, Hopkins CR, Denton JS, Piermarini PM. Pharmacological Inhibition of Inward Rectifier Potassium Channels Induces Lethality in Larval . Insects. 9. PMID 30445675 DOI: 10.3390/Insects9040163 |
0.53 |
|
| 2018 |
Carrington S, Hernandez C, Swale D, Aluko OA, Denton JS, Cone R. G protein-coupled receptors differentially regulate glycosylation and activity of the inwardly rectifying potassium channel Kir7.1. The Journal of Biological Chemistry. PMID 30257863 DOI: 10.1074/Jbc.Ra118.003238 |
0.502 |
|
| 2018 |
Piermarini PM, Inocente EA, Acosta N, Hopkins CR, Denton JS, Michel AP. Inward rectifier potassium (Kir) channels in the soybean aphid Aphis glycines: Functional characterization, pharmacology, and toxicology. Journal of Insect Physiology. 110: 57-65. PMID 30196125 DOI: 10.1016/J.Jinsphys.2018.09.001 |
0.532 |
|
| 2018 |
Kozek KA, Du Y, Sharma S, Prael FJ, Spitznagel BD, Kharade SV, Denton JS, Hopkins CR, Weaver CD. Discovery and Characterization of VU0529331, a Synthetic Small-Molecule Activator of Homomeric G Protein-gated, Inwardly-rectifying, Potassium (GIRK) Channels. Acs Chemical Neuroscience. PMID 30136838 DOI: 10.1021/Acschemneuro.8B00287 |
0.526 |
|
| 2018 |
Kharade SV, Kurata H, Bender A, Blobaum AL, Figueroa EE, Duran AM, Kramer M, Days E, Vinson P, Flores D, Satlin LM, Meiler J, Weaver CD, Lindsley CW, Hopkins CR, ... Denton JS, et al. Discovery, characterization, and effects on renal fluid and electrolyte excretion of the Kir4.1 potassium channel pore blocker, VU0134992. Molecular Pharmacology. PMID 29895592 DOI: 10.1124/Mol.118.112359 |
0.497 |
|
| 2018 |
Sammons MF, Kharade SV, Filipski KJ, Boehm M, Smith AC, Shavnya A, Fernando DP, Dowling MS, Carpino PA, Castle NA, Zellmer SG, Antonio BM, Gosset JR, Carlo A, Denton JS. Discovery and in Vitro Optimization of 3-Sulfamoylbenzamides as ROMK Inhibitors. Acs Medicinal Chemistry Letters. 9: 125-130. PMID 29456800 DOI: 10.1021/Acsmedchemlett.7B00481 |
0.366 |
|
| 2017 |
Shahi PK, Liu X, Aul B, Moyer A, Pattnaik A, Denton J, Pillers DM, Pattnaik BR. Abnormal Electroretinogram after Kir7.1 Channel Suppression Suggests Role in Retinal Electrophysiology Scientific Reports. 7: 10651-10651. PMID 28878288 DOI: 10.1038/S41598-017-11034-1 |
0.418 |
|
| 2017 |
Kharade S, Sheehan J, Figueroa E, Meiler J, Denton J. Pore polarity and charge determine differential block of Kir1.1 and Kir7.1 potassium channels by the small-molecule inhibitor VU590. Molecular Pharmacology. PMID 28619748 DOI: 10.1124/Mol.117.108472 |
0.486 |
|
| 2017 |
Piermarini PM, Esquivel CJ, Denton JS. Malpighian Tubules as Novel Targets for Mosquito Control. International Journal of Environmental Research and Public Health. 14. PMID 28125032 DOI: 10.3390/Ijerph14020111 |
0.379 |
|
| 2016 |
Swale DR, Engers DW, Bollinger SR, Gross A, Inocente EA, Days E, Kanga F, Johnson RM, Yang L, Bloomquist JR, Hopkins CR, Piermarini PM, Denton JS. An insecticide resistance-breaking mosquitocide targeting inward rectifier potassium channels in vectors of Zika virus and malaria. Scientific Reports. 6: 36954. PMID 27849039 DOI: 10.1038/Srep36954 |
0.459 |
|
| 2016 |
Yang Z, Statler BM, Calkins TL, Alfaro E, Esquivel CJ, Rouhier MF, Denton JS, Piermarini PM. Dynamic expression of genes encoding subunits of inward rectifier potassium (Kir) channels in the yellow fever mosquito Aedes aegypti. Comparative Biochemistry and Physiology. Part B, Biochemistry & Molecular Biology. PMID 27836744 DOI: 10.1016/J.Cbpb.2016.11.003 |
0.442 |
|
| 2016 |
Martin GM, Rex EA, Devaraneni P, Denton JS, Boodhansingh KE, DeLeon DD, Stanley CA, Shyng SL. Pharmacological Correction of Trafficking Defects in ATP-Sensitive Potassium Channels Caused by Sulfonylurea Receptor 1 Mutations. The Journal of Biological Chemistry. PMID 27573238 DOI: 10.1074/Jbc.M116.749366 |
0.53 |
|
| 2016 |
Swale DR, Kurata H, Kharade SV, Sheehan JH, Raphemot RR, Voigtritter KR, Figueroa E, Meiler J, Flobaum AL, Lindsley CW, Hopkins CR, Denton JS. ML418: The first selective, sub-micromolar pore blocker of Kir7.1 potassium channels. Acs Chemical Neuroscience. PMID 27184474 DOI: 10.1021/Acschemneuro.6B00111 |
0.502 |
|
| 2016 |
Kharade SV, Nichols C, Denton JS. The shifting landscape of KATP channelopathies and the need for 'sharper' therapeutics. Future Medicinal Chemistry. PMID 27161588 DOI: 10.4155/Fmc-2016-0005 |
0.432 |
|
| 2015 |
Beyenbach KW, Yu Y, Piermarini PM, Denton J. Targeting renal epithelial channels for the control of insect vectors. Tissue Barriers. 3: e1081861. PMID 26716074 DOI: 10.1080/21688370.2015.1081861 |
0.441 |
|
| 2015 |
Kharade SV, Flores D, Lindsley CW, Satlin LM, Denton JS. ROMK Inhibitor Actions in the Nephron Probed with Diuretics. American Journal of Physiology. Renal Physiology. ajprenal.00423.2015. PMID 26661652 DOI: 10.1152/Ajprenal.00423.2015 |
0.406 |
|
| 2015 |
Piermarini PM, Dunemann SM, Rouhier MF, Calkins TL, Raphemot R, Denton JS, Hine RM, Beyenbach KW. Localization and role of inward rectifier K(+) channels in Malpighian tubules of the yellow fever mosquito Aedes aegypti. Insect Biochemistry and Molecular Biology. 67: 59-73. PMID 26079629 DOI: 10.1016/J.Ibmb.2015.06.006 |
0.448 |
|
| 2015 |
Swale DR, Sheehan JH, Banerjee S, Husni AS, Nguyen TT, Meiler J, Denton JS. Computational and functional analyses of a small-molecule binding site in ROMK. Biophysical Journal. 108: 1094-103. PMID 25762321 DOI: 10.1016/J.Bpj.2015.01.022 |
0.428 |
|
| 2015 |
Ghamari-Langroudi M, Digby GJ, Sebag JA, Millhauser GL, Palomino R, Matthews R, Gillyard T, Panaro BL, Tough IR, Cox HM, Denton JS, Cone RD. G-protein-independent coupling of MC4R to Kir7.1 in hypothalamic neurons. Nature. 520: 94-8. PMID 25600267 DOI: 10.1038/Nature14051 |
0.329 |
|
| 2014 |
Raphemot R, Rouhier MF, Swale DR, Days E, Weaver CD, Lovell KM, Konkel LC, Engers DW, Bollinger SR, Bollinger SF, Hopkins C, Piermarini PM, Denton JS. Discovery and characterization of a potent and selective inhibitor of Aedes aegypti inward rectifier potassium channels. Plos One. 9: e110772. PMID 25375326 DOI: 10.1371/Journal.Pone.0110772 |
0.46 |
|
| 2014 |
McCloskey C, Rada C, Bailey E, McCavera S, van den Berg HA, Atia J, Rand DA, Shmygol A, Chan YW, Quenby S, Brosens JJ, Vatish M, Zhang J, Denton JS, Taggart MJ, et al. The inwardly rectifying K+ channel KIR7.1 controls uterine excitability throughout pregnancy. Embo Molecular Medicine. 6: 1161-74. PMID 25056913 DOI: 10.15252/Emmm.201403944 |
0.385 |
|
| 2014 |
Rouhier MF, Hine RM, Park ST, Raphemot R, Denton J, Piermarini PM, Beyenbach KW. Excretion of NaCl and KCl loads in mosquitoes. 2. Effects of the small molecule Kir channel modulator VU573 and its inactive analog VU342. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 307: R850-61. PMID 25056106 DOI: 10.1152/Ajpregu.00106.2014 |
0.36 |
|
| 2014 |
Rouhier MF, Raphemot R, Denton JS, Piermarini PM. Pharmacological validation of an inward-rectifier potassium (Kir) channel as an insecticide target in the yellow fever mosquito Aedes aegypti. Plos One. 9: e100700. PMID 24959745 DOI: 10.1371/Journal.Pone.0100700 |
0.498 |
|
| 2014 |
Raphemot R, Estévez-Lao TY, Rouhier MF, Piermarini PM, Denton JS, Hillyer JF. Molecular and functional characterization of Anopheles gambiae inward rectifier potassium (Kir1) channels: a novel role in egg production. Insect Biochemistry and Molecular Biology. 51: 10-9. PMID 24855023 DOI: 10.1016/J.Ibmb.2014.05.002 |
0.486 |
|
| 2014 |
Swale DR, Kharade SV, Denton JS. Cardiac and renal inward rectifier potassium channel pharmacology: emerging tools for integrative physiology and therapeutics. Current Opinion in Pharmacology. 15: 7-15. PMID 24721648 DOI: 10.1016/J.Coph.2013.11.002 |
0.485 |
|
| 2014 |
Raphemot R, Swale DR, Dadi PK, Jacobson DA, Cooper P, Wojtovich AP, Banerjee S, Nichols CG, Denton JS. Direct activation of β-cell KATP channels with a novel xanthine derivative. Molecular Pharmacology. 85: 858-65. PMID 24646456 DOI: 10.1124/Mol.114.091884 |
0.539 |
|
| 2013 |
Raphemot R, Kadakia RJ, Olsen ML, Banerjee S, Days E, Smith SS, Weaver CD, Denton JS. Development and validation of fluorescence-based and automated patch clamp-based functional assays for the inward rectifier potassium channel Kir4.1. Assay and Drug Development Technologies. 11: 532-43. PMID 24266659 DOI: 10.1089/adt.2013.544 |
0.373 |
|
| 2013 |
Denton JS, Pao AC, Maduke M. Novel diuretic targets. American Journal of Physiology. Renal Physiology. 305: F931-42. PMID 23863472 DOI: 10.1152/Ajprenal.00230.2013 |
0.434 |
|
| 2013 |
Raphemot R, Rouhier MF, Hopkins CR, Gogliotti RD, Lovell KM, Hine RM, Ghosalkar D, Longo A, Beyenbach KW, Denton JS, Piermarini PM. Eliciting renal failure in mosquitoes with a small-molecule inhibitor of inward-rectifying potassium channels. Plos One. 8: e64905. PMID 23734226 DOI: 10.1371/Journal.Pone.0064905 |
0.495 |
|
| 2013 |
Kaufmann K, Romaine I, Days E, Pascual C, Malik A, Yang L, Zou B, Du Y, Sliwoski G, Morrison RD, Denton J, Niswender CM, Daniels JS, Sulikowski GA, Xie XS, et al. ML297 (VU0456810), the first potent and selective activator of the GIRK potassium channel, displays antiepileptic properties in mice. Acs Chemical Neuroscience. 4: 1278-86. PMID 23730969 DOI: 10.1021/Cn400062A |
0.479 |
|
| 2013 |
Raphemot R, Weaver CD, Denton JS. High-throughput screening for small-molecule modulators of inward rectifier potassium channels. Journal of Visualized Experiments : Jove. PMID 23381507 DOI: 10.3791/4209 |
0.485 |
|
| 2012 |
Denton JS, Jacobson DA. Channeling dysglycemia: Ion-channel variations perturbing glucose homeostasis Trends in Endocrinology and Metabolism. 23: 41-48. PMID 22134088 DOI: 10.1016/J.Tem.2011.09.004 |
0.397 |
|
| 2011 |
Raphemot R, Lonergan DF, Nguyen TT, Utley T, Lewis LM, Kadakia R, Weaver CD, Gogliotti R, Hopkins C, Lindsley CW, Denton JS. Discovery, characterization, and structure-activity relationships of an inhibitor of inward rectifier potassium (Kir) channels with preference for Kir2.3, Kir3.x, and Kir7.1. Frontiers in Pharmacology. 2: 75. PMID 22275899 DOI: 10.3389/Fphar.2011.00075 |
0.532 |
|
| 2011 |
Bhave G, Chauder BA, Liu W, Dawson ES, Kadakia R, Nguyen TT, Lewis LM, Meiler J, Weaver CD, Satlin LM, Lindsley CW, Denton JS. Development of a selective small-molecule inhibitor of Kir1.1, the renal outer medullary potassium channel. Molecular Pharmacology. 79: 42-50. PMID 20926757 DOI: 10.1124/Mol.110.066928 |
0.466 |
|
| 2010 |
Bhave G, Lonergan D, Chauder BA, Denton JS. Small-molecule modulators of inward rectifier K+ channels: recent advances and future possibilities. Future Medicinal Chemistry. 2: 757-74. PMID 20543968 DOI: 10.4155/Fmc.10.179 |
0.491 |
|
| 2010 |
Bhave G, Chauder BA, Kadakia R, Dawson ES, Lindsley CW, Weaver CD, Denton JS. 55: Rational Synthesis of a Selective Renal Outer Medullary Potassium Channel (ROMK) Antagonist American Journal of Kidney Diseases. 55: B45. DOI: 10.1053/J.Ajkd.2010.02.062 |
0.431 |
|
| 2010 |
Denton JS, Chauder BA, Kadakia R, Dawson ES, Lindsley C, Weaver CD, Bhave G. Chemical Synthesis of a Highly Selective Probe of the Renal Outer Medullary Potassium Channel (ROMK) Biophysical Journal. 98: 755a. DOI: 10.1016/J.Bpj.2009.12.4144 |
0.484 |
|
| 2009 |
Lewis LM, Bhave G, Chauder BA, Banerjee S, Lornsen KA, Redha R, Fallen K, Lindsley CW, Weaver CD, Denton JS. High-throughput screening reveals a small-molecule inhibitor of the renal outer medullary potassium channel and Kir7.1. Molecular Pharmacology. 76: 1094-103. PMID 19706730 DOI: 10.1124/Mol.109.059840 |
0.5 |
|
| 2009 |
Fallen K, Banerjee S, Sheehan J, Addison D, Lewis LM, Meiler J, Denton JS. The Kir channel immunoglobulin domain is essential for Kir1.1 (ROMK) thermodynamic stability, trafficking and gating. Channels (Austin, Tex.). 3: 57-68. PMID 19221509 DOI: 10.4161/Chan.3.1.7817 |
0.475 |
|
| 2007 |
Denton JS, McCann FV, Leiter JC. CO2 chemosensitivity in Helix aspersa: three potassium currents mediate pH-sensitive neuronal spike timing. American Journal of Physiology. Cell Physiology. 292: C292-304. PMID 16928774 DOI: 10.1152/Ajpcell.00172.2006 |
0.674 |
|
| 2007 |
Chernov MM, Daubenspeck JA, Denton JS, Pfeiffer JR, Putnam RW, Leiter JC. A computational analysis of central CO2 chemosensitivity in Helix aspersa. American Journal of Physiology. Cell Physiology. 292: C278-91. PMID 16928773 DOI: 10.1152/Ajpcell.00173.2006 |
0.686 |
|
| 2007 |
Yin X, Denton J, Yan X, Strange K. Characterization of a novel voltage-dependent outwardly rectifying anion current in Caenorhabditis elegans oocytes. American Journal of Physiology. Cell Physiology. 292: C269-77. PMID 16899547 DOI: 10.1152/Ajpcell.00298.2006 |
0.498 |
|
| 2006 |
He L, Denton J, Nehrke K, Strange K. Carboxy terminus splice variation alters ClC channel gating and extracellular cysteine reactivity. Biophysical Journal. 90: 3570-81. PMID 16500974 DOI: 10.1529/Biophysj.105.078295 |
0.397 |
|
| 2006 |
Denton J, Nehrke K, Yin X, Beld AM, Strange K. Altered gating and regulation of a carboxy-terminal ClC channel mutant expressed in the Caenorhabditis elegans oocyte. American Journal of Physiology. Cell Physiology. 290: C1109-18. PMID 16306126 DOI: 10.1152/Ajpcell.00423.2005 |
0.511 |
|
| 2005 |
Denton J, Nehrke K, Yin X, Morrison R, Strange K. GCK-3, a newly identified Ste20 kinase, binds to and regulates the activity of a cell cycle-dependent ClC anion channel. The Journal of General Physiology. 125: 113-25. PMID 15684092 DOI: 10.1085/Jgp.200409215 |
0.463 |
|
| 2004 |
Denton J, Nehrke K, Rutledge E, Morrison R, Strange K. Alternative splicing of N- and C-termini of a C. elegans ClC channel alters gating and sensitivity to external Cl- and H+. The Journal of Physiology. 555: 97-114. PMID 14565992 DOI: 10.1113/Jphysiol.2003.053165 |
0.474 |
|
| 2002 |
Denton JS, Leiter JC. Anomalous effects of external TEA on permeation and gating of the A-type potassium current in H. aspersa neuronal somata. The Journal of Membrane Biology. 190: 17-28. PMID 12422269 DOI: 10.1007/s00232-002-1021-9 |
0.631 |
|
| 2002 |
Rutledge E, Denton J, Strange K. Cell cycle- and swelling-induced activation of a Caenorhabditis elegans ClC channel is mediated by CeGLC-7alpha/beta phosphatases. The Journal of Cell Biology. 158: 435-44. PMID 12163466 DOI: 10.1083/Jcb.200204142 |
0.517 |
|
| 2000 |
Moyer BD, Duhaime M, Shaw C, Denton J, Reynolds D, Karlson KH, Pfeiffer J, Wang S, Mickle JE, Milewski M, Cutting GR, Guggino WB, Li M, Stanton BA. The PDZ-interacting domain of cystic fibrosis transmembrane conductance regulator is required for functional expression in the apical plasma membrane. The Journal of Biological Chemistry. 275: 27069-74. PMID 10852925 DOI: 10.1074/Jbc.M004951200 |
0.625 |
|
| 1999 |
Moyer BD, Denton J, Karlson KH, Reynolds D, Wang S, Mickle JE, Milewski M, Cutting GR, Guggino WB, Li M, Stanton BA. A PDZ-interacting domain in CFTR is an apical membrane polarization signal. The Journal of Clinical Investigation. 104: 1353-61. PMID 10562297 DOI: 10.1172/Jci7453 |
0.374 |
|
| 1999 |
Chalfant ML, Denton JS, Langloh AL, Karlson KH, Loffing J, Benos DJ, Stanton BA. The NH(2) terminus of the epithelial sodium channel contains an endocytic motif. The Journal of Biological Chemistry. 274: 32889-96. PMID 10551853 DOI: 10.1074/Jbc.274.46.32889 |
0.425 |
|
| 1999 |
Chalfant ML, Denton JS, Berdiev BK, Ismailov II, Benos DJ, Stanton BA. Intracellular H+ regulates the α-subunit of ENaC, the epithelial Na+ channel American Journal of Physiology - Cell Physiology. 276. PMID 9950776 DOI: 10.1152/Ajpcell.1999.276.2.C477 |
0.468 |
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