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George L. Sen, Ph.D. - Publications

Affiliations: 
2006 Stanford University, Palo Alto, CA 
Area:
Molecular Biology
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31 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Li J, Tiwari M, Chen Y, Luanpitpong S, Sen GL. CDK12 Is Necessary to Promote Epidermal Differentiation Through Transcription Elongation. Stem Cells (Dayton, Ohio). PMID 35325240 DOI: 10.1093/stmcls/sxac002  0.317
2021 Li J, Chen Y, Tiwari M, Bansal V, Sen GL. Regulation of integrin and extracellular matrix genes by HNRNPL is necessary for epidermal renewal. Plos Biology. 19: e3001378. PMID 34543262 DOI: 10.1371/journal.pbio.3001378  0.395
2021 Li J, Xu X, Tiwari M, Chen Y, Fuller M, Bansal V, Tamayo P, Das S, Ghosh P, Sen GL. SPT6 promotes epidermal differentiation and blockade of an intestinal-like phenotype through control of transcriptional elongation. Nature Communications. 12: 784. PMID 33542242 DOI: 10.1038/s41467-021-21067-w  0.368
2020 Li J, Bansal V, Tiwari M, Chen Y, Sen GL. ELL facilitates RNA Polymerase II mediated transcription of human epidermal proliferation genes. The Journal of Investigative Dermatology. PMID 33157094 DOI: 10.1016/j.jid.2020.09.024  0.329
2020 Jones J, Chen Y, Tiwari M, Li J, Ling J, Sen GL. KLF3 Mediates Epidermal Differentiation through the Epigenomic Writer CBP. Iscience. 23: 101320. PMID 32659720 DOI: 10.1016/J.Isci.2020.101320  0.408
2020 Jones J, Chen Y, Tiwari M, Li J, Ling J, Sen GL. BRD4 is necessary for differentiation downstream of epidermal lineage determining transcription factors. The Journal of Investigative Dermatology. PMID 32142793 DOI: 10.1016/J.Jid.2020.01.030  0.327
2019 Li J, Chen Y, Xu X, Jones J, Tiwari M, Ling J, Wang Y, Harismendy O, Sen GL. HNRNPK maintains epidermal progenitor function through transcription of proliferation genes and degrading differentiation promoting mRNAs. Nature Communications. 10: 4198. PMID 31519929 DOI: 10.1038/S41467-019-12238-X  0.494
2018 Chen F, Li G, Zhao ER, Li J, Hableel G, Lemaster JE, Bai Y, Sen GL, Jokerst JV. Cellular toxicity of silicon carbide nanomaterials as a function of morphology. Biomaterials. 179: 60-70. PMID 29980075 DOI: 10.1016/J.Biomaterials.2018.06.027  0.346
2017 Noutsou M, Li J, Ling J, Jones J, Wang Y, Chen Y, Sen GL. The Cohesin Complex Is Necessary for Epidermal Progenitor Cell Function through Maintenance of Self-Renewal Genes. Cell Reports. 20: 3005-3013. PMID 28954219 DOI: 10.1016/J.Celrep.2017.09.003  0.485
2017 Sato E, Williams MR, Sanford JA, Sen GL, Nakama T, Imafuku S, Gallo RL. The parathyroid hormone family member TIP39 interacts with sarco/endoplasmic reticulum Ca(2+) - ATPase activity by influencing calcium homeostasis. Experimental Dermatology. PMID 28094886 DOI: 10.1111/Exd.13294  0.333
2016 Wang Y, Sen GL. Enhanc(er)ing Skin Stem Cells. Cell Stem Cell. 19: 415-417. PMID 27716517 DOI: 10.1016/J.Stem.2016.09.003  0.402
2016 Li J, Sen GL. Post-Transcriptional Mechanisms Regulating Epidermal Stem and Progenitor Cell Self-Renewal and Differentiation. The Journal of Investigative Dermatology. 136: 746-52. PMID 26875726 DOI: 10.1016/J.Jid.2015.12.030  0.464
2016 Sen G, Wang Y. 683 DDX6 maintains epidermal progenitor function through the mRNA degradation and translation pathways Journal of Investigative Dermatology. 136: S121. DOI: 10.1016/J.Jid.2016.02.725  0.373
2015 Li J, Sen GL. Generation of Genetically Modified Organotypic Skin Cultures Using Devitalized Human Dermis. Journal of Visualized Experiments : Jove. e53280. PMID 26709715 DOI: 10.3791/53280  0.32
2015 Wang Y, Arribas-Layton M, Chen Y, Lykke-Andersen J, Sen GL. DDX6 Orchestrates Mammalian Progenitor Function through the mRNA Degradation and Translation Pathways. Molecular Cell. PMID 26412305 DOI: 10.1016/J.Molcel.2015.08.014  0.468
2015 Li G, Xu F, Zhu J, Krawczyk M, Zhang Y, Yuan J, Patel S, Wang Y, Lin Y, Zhang M, Cai H, Chen D, Zhang M, Cao G, Yeh E, ... ... Sen GL, et al. Transcription factor Paired Box 6 controls limbal stem cell lineage in development and disease. The Journal of Biological Chemistry. PMID 26045558 DOI: 10.1074/Jbc.M115.662940  0.398
2015 Mistry DS, Chen Y, Wang Y, Sen GL. Transcriptional profiling of SNAI2 regulated genes in primary human keratinocytes. Genomics Data. 4: 43-46. PMID 25793155 DOI: 10.1016/J.Gdata.2015.02.002  0.469
2014 Mistry DS, Chen Y, Wang Y, Zhang K, Sen GL. SNAI2 controls the undifferentiated state of human epidermal progenitor cells. Stem Cells (Dayton, Ohio). 32: 3209-18. PMID 25100569 DOI: 10.1002/Stem.1809  0.429
2014 Chen Y, Mistry DS, Sen GL. Highly rapid and efficient conversion of human fibroblasts to keratinocyte-like cells. The Journal of Investigative Dermatology. 134: 335-44. PMID 23921950 DOI: 10.1038/Jid.2013.327  0.442
2012 Zarnegar BJ, Webster DE, Lopez-Pajares V, Vander Stoep Hunt B, Qu K, Yan KJ, Berk DR, Sen GL, Khavari PA. Genomic profiling of a human organotypic model of AEC syndrome reveals ZNF750 as an essential downstream target of mutant TP63. American Journal of Human Genetics. 91: 435-43. PMID 22922031 DOI: 10.1016/J.Ajhg.2012.07.007  0.355
2012 Mistry DS, Chen Y, Sen GL. Progenitor function in self-renewing human epidermis is maintained by the exosome. Cell Stem Cell. 11: 127-35. PMID 22770246 DOI: 10.1016/J.Stem.2012.04.022  0.467
2012 Sen GL, Boxer LD, Webster DE, Bussat RT, Qu K, Zarnegar BJ, Johnston D, Siprashvili Z, Khavari PA. ZNF750 is a p63 target gene that induces KLF4 to drive terminal epidermal differentiation. Developmental Cell. 22: 669-77. PMID 22364861 DOI: 10.1016/J.Devcel.2011.12.001  0.4
2011 Sen GL. Remembering one's identity: the epigenetic basis of stem cell fate decisions. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 25: 2123-8. PMID 21441350 DOI: 10.1096/Fj.11-182774  0.386
2010 Khavari DA, Sen GL, Rinn JL. DNA methylation and epigenetic control of cellular differentiation. Cell Cycle (Georgetown, Tex.). 9: 3880-3. PMID 20890116 DOI: 10.4161/Cc.9.19.13385  0.446
2010 Sen GL, Reuter JA, Webster DE, Zhu L, Khavari PA. DNMT1 maintains progenitor function in self-renewing somatic tissue. Nature. 463: 563-7. PMID 20081831 DOI: 10.1038/Nature08683  0.445
2008 Sen GL, Webster DE, Barragan DI, Chang HY, Khavari PA. Control of differentiation in a self-renewing mammalian tissue by the histone demethylase JMJD3. Genes & Development. 22: 1865-70. PMID 18628393 DOI: 10.1101/Gad.1673508  0.423
2007 Zhang F, Pomerantz JH, Sen G, Palermo AT, Blau HM. Active tissue-specific DNA demethylation conferred by somatic cell nuclei in stable heterokaryons. Proceedings of the National Academy of Sciences of the United States of America. 104: 4395-400. PMID 17360535 DOI: 10.1073/Pnas.0700181104  0.623
2006 Sen GL, Blau HM. A brief history of RNAi: the silence of the genes. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 20: 1293-9. PMID 16816104 DOI: 10.1096/Fj.06-6014Rev  0.59
2005 Sen GL, Wehrman TS, Blau HM. mRNA translation is not a prerequisite for small interfering RNA-mediated mRNA cleavage. Differentiation; Research in Biological Diversity. 73: 287-93. PMID 16138829 DOI: 10.1111/J.1432-0436.2005.00029.X  0.661
2005 Sen GL, Blau HM. Argonaute 2/RISC resides in sites of mammalian mRNA decay known as cytoplasmic bodies. Nature Cell Biology. 7: 633-6. PMID 15908945 DOI: 10.1038/Ncb1265  0.561
2004 Sen G, Wehrman TS, Myers JW, Blau HM. Restriction enzyme-generated siRNA (REGS) vectors and libraries. Nature Genetics. 36: 183-9. PMID 14704668 DOI: 10.1038/Ng1288  0.674
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