Year |
Citation |
Score |
2023 |
Difede J, McAleavey AA, Emrich M, Jick A, Ovalles A, Wyka K, Spielman L, Olden M, Peskin M, Becket-Davenport C, Rubenstein A, Brownstein MJ, Damiano E, Itzkowitz D, Lu SF, ... ... Simon NG, et al. A proof-of-concept randomized crossover clinical trial of a first-in-class vasopressin 1a receptor antagonist for PTSD: Design, methods, and recruitment. Contemporary Clinical Trials Communications. 33: 101116. PMID 37008794 DOI: 10.1016/j.conctc.2023.101116 |
0.445 |
|
2020 |
Lago T, Brownstein M, Beydler E, Manbeck A, Beale A, Simon N, Ernst M, Grillon C. Effects of SRX246, a Vasopressin 1a Receptor (V1a) Antagonist, on an Experimental Model of Phasic and Sustained Threat in Humans Biological Psychiatry. 87: S167-S168. DOI: 10.1016/J.Biopsych.2020.02.443 |
0.36 |
|
2019 |
Morrison TR, Kulkarni P, Cai X, Iriah S, Aggarwal D, Lu SF, Simon NG, Madularu D, Ferris CF. Treating Head Injury using a Novel Vasopressin 1a Receptor Antagonist. Neuroscience Letters. 134565. PMID 31639422 DOI: 10.1016/J.Neulet.2019.134565 |
0.575 |
|
2013 |
Lee RJ, Coccaro EF, Cremers H, McCarron R, Lu SF, Brownstein MJ, Simon NG. A novel V1a receptor antagonist blocks vasopressin-induced changes in the CNS response to emotional stimuli: an fMRI study. Frontiers in Systems Neuroscience. 7: 100. PMID 24376401 DOI: 10.3389/Fnsys.2013.00100 |
0.575 |
|
2013 |
Fabio KM, Guillon CD, Lu SF, Heindel ND, Brownstein MJ, Lacey CJ, Garippa C, Simon NG. Pharmacokinetics and metabolism of SRX246: a potent and selective vasopressin 1a antagonist. Journal of Pharmaceutical Sciences. 102: 2033-43. PMID 23471831 DOI: 10.1002/Jps.23495 |
0.56 |
|
2012 |
Fabio K, Guillon C, Lacey CJ, Lu SF, Heindel ND, Ferris CF, Placzek M, Jones G, Brownstein MJ, Simon NG. Synthesis and evaluation of potent and selective human V1a receptor antagonists as potential ligands for PET or SPECT imaging. Bioorganic & Medicinal Chemistry. 20: 1337-45. PMID 22249122 DOI: 10.1016/J.Bmc.2011.12.013 |
0.561 |
|
2009 |
Mo Q, Lu S, Garippa C, Brownstein MJ, Simon NG. Genome-wide analysis of DHEA- and DHT-induced gene expression in mouse hypothalamus and hippocampus. The Journal of Steroid Biochemistry and Molecular Biology. 114: 135-43. PMID 19429443 DOI: 10.1016/J.Jsbmb.2009.01.015 |
0.686 |
|
2008 |
Ferris CF, Stolberg T, Kulkarni P, Murugavel M, Blanchard R, Blanchard DC, Febo M, Brevard M, Simon NG. Imaging the neural circuitry and chemical control of aggressive motivation. Bmc Neuroscience. 9: 111. PMID 19014547 DOI: 10.1186/1471-2202-9-111 |
0.386 |
|
2008 |
Simon NG, Guillon C, Fabio K, Heindel ND, Lu SF, Miller M, Ferris CF, Brownstein MJ, Garripa C, Koppel GA. Vasopressin antagonists as anxiolytics and antidepressants: recent developments. Recent Patents On Cns Drug Discovery. 3: 77-93. PMID 18537767 DOI: 10.2174/157488908784534586 |
0.536 |
|
2007 |
Guillon CD, Koppel GA, Brownstein MJ, Chaney MO, Ferris CF, Lu SF, Fabio KM, Miller MJ, Heindel ND, Hunden DC, Cooper RD, Kaldor SW, Skelton JJ, Dressman BA, Clay MP, ... ... Simon NG, et al. Azetidinones as vasopressin V1a antagonists. Bioorganic & Medicinal Chemistry. 15: 2054-80. PMID 17234419 DOI: 10.1016/J.Bmc.2006.12.031 |
0.597 |
|
2006 |
Simon NG, Mo Q, Hu S, Garippa C, Lu SF. Hormonal pathways regulating intermale and interfemale aggression. International Review of Neurobiology. 73: 99-123. PMID 16737902 DOI: 10.1016/S0074-7742(06)73003-3 |
0.679 |
|
2006 |
Mo Q, Lu SF, Simon NG. Dehydroepiandrosterone and its metabolites: differential effects on androgen receptor trafficking and transcriptional activity. The Journal of Steroid Biochemistry and Molecular Biology. 99: 50-8. PMID 16524719 DOI: 10.1016/J.Jsbmb.2005.11.011 |
0.676 |
|
2006 |
Ferris CF, Lu SF, Messenger T, Guillon CD, Heindel N, Miller M, Koppel G, Robert Bruns F, Simon NG. Orally active vasopressin V1a receptor antagonist, SRX251, selectively blocks aggressive behavior. Pharmacology, Biochemistry, and Behavior. 83: 169-74. PMID 16504276 DOI: 10.1016/J.Pbb.2006.01.001 |
0.632 |
|
2005 |
Hu S, Lu SF, Kaplan JR, Adams MR, Simon NG. ERbeta protein expression in female cynomolgus monkey and CF-1 mouse brain: Western analysis. Journal of Neurobiology. 64: 298-309. PMID 15898060 DOI: 10.1002/Neu.20139 |
0.584 |
|
2005 |
Simon NG, Lu SF. Androgens and Aggression Biology of Aggression. DOI: 10.1093/acprof:oso/9780195168761.003.0009 |
0.525 |
|
2004 |
Mo Q, Lu SF, Hu S, Simon NG. DHEA and DHEA sulfate differentially regulate neural androgen receptor and its transcriptional activity. Brain Research. Molecular Brain Research. 126: 165-72. PMID 15249140 DOI: 10.1016/J.Molbrainres.2004.05.001 |
0.699 |
|
2004 |
Simon NG, Kaplan JR, Hu S, Register TC, Adams MR. Increased aggressive behavior and decreased affiliative behavior in adult male monkeys after long-term consumption of diets rich in soy protein and isoflavones. Hormones and Behavior. 45: 278-84. PMID 15053944 DOI: 10.1016/J.Yhbeh.2003.12.005 |
0.379 |
|
2003 |
Lu SF, Mo Q, Hu S, Garippa C, Simon NG. Dehydroepiandrosterone upregulates neural androgen receptor level and transcriptional activity. Journal of Neurobiology. 57: 163-71. PMID 14556282 DOI: 10.1002/Neu.10260 |
0.708 |
|
2002 |
Simon NG. Hormonal Processes in the Development and Expression of Aggressive Behavior Hormones, Brain and Behavior. 339-392. DOI: 10.1016/B978-012532104-4/50007-X |
0.467 |
|
2001 |
Perché F, Young J, Robel P, Simon NG, Haug M. Prenatal testosterone treatment potentiates the aggression-inhibiting effect of the neurosteroid dehydroepiandrosterone in female mice Aggressive Behavior. 27: 130-138. DOI: 10.1002/Ab.5 |
0.43 |
|
1999 |
Lu S, Simon NG, Wang Y, Hu S. Neural androgen receptor regulation: Effects of androgen and antiandrogen Journal of Neurobiology. 41: 505-512. PMID 10590174 DOI: 10.1002/(Sici)1097-4695(199912)41:4<505::Aid-Neu6>3.0.Co;2-N |
0.648 |
|
1998 |
Cologer-Clifford A, Simon NG, Richter ML, Smoluk SA, Lu S. Androgens and estrogens modulate 5-HT(1A) and 5-HT(1B) agonist effects on aggression Physiology and Behavior. 65: 823-828. PMID 10073487 DOI: 10.1016/S0031-9384(98)00240-6 |
0.564 |
|
1998 |
Simon NG, Cologer-Clifford A, Lu SF, McKenna SE, Hu S. Testosterone and its metabolites modulate 5HT1A and 5HT1B agonist effects on intermale aggression. Neuroscience and Biobehavioral Reviews. 23: 325-36. PMID 9884126 DOI: 10.1016/S0149-7634(98)00034-7 |
0.656 |
|
1998 |
Lu SF, McKenna SE, Cologer-Clifford A, Nau EA, Simon NG. Androgen receptor in mouse brain: sex differences and similarities in autoregulation. Endocrinology. 139: 1594-601. PMID 9528939 DOI: 10.1210/Endo.139.4.5863 |
0.642 |
|
1997 |
Cologer-Clifford A, Simon NG, Lu SF, Smoluk SA. Serotonin agonist-induced decreases in intermale aggression are dependent on brain region and receptor subtype. Pharmacology, Biochemistry, and Behavior. 58: 425-30. PMID 9300602 DOI: 10.1016/S0091-3057(97)00295-5 |
0.651 |
|
1996 |
Cologer-Clifford A, Smoluk SA, Simon NG. Effects of serotonergic(1A) and (1B) agonists in androgenic versus estrogenic systems for aggression Annals of the New York Academy of Sciences. 794: 339-342. PMID 8853615 DOI: 10.1111/J.1749-6632.1996.Tb32536.X |
0.358 |
|
1996 |
Simon NG, McKenna SE, Lu SF, Cologer-Clifford A. Development and expression of hormonal systems regulating aggression. Annals of the New York Academy of Sciences. 794: 8-17. PMID 8853588 DOI: 10.1111/J.1749-6632.1996.Tb32505.X |
0.623 |
|
1993 |
McKenna SE, Simon NG. Genetic differences in progestin sensitivity in CD-1 and SW female mice Physiology and Behavior. 54: 167-170. PMID 8327597 DOI: 10.1016/0031-9384(93)90060-S |
0.361 |
|
1992 |
Cologer-Clifford A, Simon NG, Jubilan BM. Genotype, uterine position, and testosterone sensitivity in older female mice Physiology and Behavior. 51: 1047-1050. PMID 1615042 DOI: 10.1016/0031-9384(92)90090-O |
0.366 |
|
1992 |
McKenna SE, Simon NG, Cologer-Clifford A. An assessment of agonist/antagonist effects of tamoxifen in the female mouse brain Hormones and Behavior. 26: 536-544. PMID 1478637 DOI: 10.1016/0018-506X(92)90020-V |
0.494 |
|
1991 |
Klein WP, Simon NG. Timing of neonatal testosterone exposure in the differentiation of estrogenic regulatory systems for aggression Physiology and Behavior. 50: 91-93. PMID 1946737 DOI: 10.1016/0031-9384(91)90503-G |
0.404 |
|
1991 |
Simon NG, Cologer-Clifford A. In utero contiguity to males does not influence morphology, behavioral sensitivity to testosterone, or hypothalamic androgen binding in CF-1 female mice Hormones and Behavior. 25: 518-530. PMID 1813378 DOI: 10.1016/0018-506X(91)90018-D |
0.407 |
|
1990 |
Chen X, Simon NG. Genetic variation in hypothalamic methyltrienolone (R1881) binding in male mice Physiology and Behavior. 47: 589-592. PMID 2359772 DOI: 10.1016/0031-9384(90)90130-V |
0.38 |
|
1988 |
Simon NG, Perry M. Medroxyprogesterone acetate and tamoxifen do not decrease aggressive behavior in CF-1 male mice Pharmacology, Biochemistry and Behavior. 30: 829-833. PMID 2976166 DOI: 10.1016/0091-3057(88)90107-4 |
0.389 |
|
1988 |
Simon NG, Masters DB. Activation of intermale aggression by combined estrogen‐androgen treatment Aggressive Behavior. 14: 291-295. DOI: 10.1002/1098-2337(1988)14:4<291::Aid-Ab2480140407>3.0.Co;2-D |
0.429 |
|
1987 |
Nyby JG, Simon NG. Nonaromatizable androgens may stimulate a male mouse reproductive behavior by binding estrogen receptors. Physiology & Behavior. 39: 147-51. PMID 3575447 DOI: 10.1016/0031-9384(87)90003-5 |
0.422 |
|
1987 |
Simon NG, Masters DB. Activation of male-typical aggression by testosterone but not its metabolites in C57BL/6J female mice Physiology and Behavior. 41: 405-407. PMID 3501596 DOI: 10.1016/0031-9384(87)90073-4 |
0.454 |
|
1987 |
Simon NG, Whalen RE. Sexual differentiation of androgen-sensitive and estrogen-sensitive regulatory systems for aggressive behavior. Hormones and Behavior. 21: 493-500. PMID 3501394 DOI: 10.1016/0018-506X(87)90007-9 |
0.439 |
|
1986 |
Wachtel S, Green R, Simon NG, Reichart A, Cahill L, Hall J, Nakamura D, Wachtel G, Futterweit W, Biber SH. On the expression of H-Y antigen in transsexuals. Archives of Sexual Behavior. 15: 51-68. PMID 3964070 DOI: 10.1007/Bf01542304 |
0.305 |
|
1986 |
Simon NG, Whalen RE. Hormonal regulation of aggression: Evidence for a relationship among genotype, receptor binding, and behavioral sensitivity to androgen and estrogen Aggressive Behavior. 12: 255-266. DOI: 10.1002/1098-2337(1986)12:4<255::Aid-Ab2480120404>3.0.Co;2-S |
0.459 |
|
1985 |
Simon NG, Whalen RE, Tate MP. Induction of male-typical aggression by androgens but not by estrogens in adult female mice. Hormones and Behavior. 19: 204-12. PMID 3874138 DOI: 10.1016/0018-506X(85)90019-4 |
0.44 |
|
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