Robert F. Rakowski - Related publications

Washington University, Saint Louis, St. Louis, MO 
 Rosalind Franklin University of Medicine and Science, North Chicago, IL, United States 
synaptic transmission, ion channels
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50 most relevant papers in past 60 days:
Year Citation  Score
2020 Chen X, Bründl M, Friesacher T, Stary-Weinzinger A. Computational Insights Into Voltage Dependence of Polyamine Block in a Strong Inwardly Rectifying K Channel. Frontiers in Pharmacology. 11: 721. PMID 32499707 DOI: 10.3389/fphar.2020.00721   
2020 Moreno C, Yano S, Bezanilla F, Latorre R, Holmgren M. Transient Electrical Currents Mediated by the Na/K-ATPase: A Tour from Basic Biophysics to Human Diseases. Biophysical Journal. PMID 32579966 DOI: 10.1016/j.bpj.2020.06.006   
2020 Fahanik-Babaei J, Rezaee B, Nazari M, Torabi N, Saghiri R, Sauve R, Eliassi A. A new brain mitochondrial sodium-sensitive potassium channel: effect of sodium ions on respiratory chain activity. Journal of Cell Science. PMID 32327555 DOI: 10.1242/jcs.242446   
2020 Rehman SM, Narayanan K, Nickerson AJ, Coon SD, Hoque KM, Sandle GI, Rajendran VM. Parallel intermediate conductance K (IK) and Cl (CLC2) channel activity mediates electroneutral K exit across basolateral membranes in rat distal colon. American Journal of Physiology. Gastrointestinal and Liver Physiology. PMID 32567323 DOI: 10.1152/ajpgi.00011.2020   
2020 Kuo PC, Kao ZH, Lee SW, Wu SN. Effects of Sesamin, the Major Furofuran Lignan of Sesame Oil, on the Amplitude and Gating of Voltage-Gated Na and K Currents. Molecules (Basel, Switzerland). 25. PMID 32635522 DOI: 10.3390/molecules25133062   
2020 Lewis A, McCrossan ZA, Manville RW, Popa MO, Cuello LG, Goldstein SAN. TOK channels use the two gates in classical K channels to achieve outward rectification. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 32519783 DOI: 10.1096/fj.202000545R   
2020 Sancho M, Welsh DG. K channels in the microvasculature: Regulatory properties and the lipid-hemodynamic environment. Current Topics in Membranes. 85: 227-259. PMID 32402641 DOI: 10.1016/bs.ctm.2020.01.006   
2020 Li C, Chen H, Chen Q, Shi H, Yang X, Wang K, Liu J. Lipophilic G-quadruplex Isomers as Biomimetic Ion Channels for Conformation- dependent Selective Transmembrane Transport. Analytical Chemistry. PMID 32564593 DOI: 10.1021/acs.analchem.0c02222   
2020 Peters CH, Watkins AR, Poirier OL, Ruben PC. E1784K, the most common Brugada syndrome and long-QT syndrome type 3 mutant, disrupts sodium channel inactivation through two separate mechanisms. The Journal of General Physiology. 152. PMID 32569350 DOI: 10.1085/jgp.202012595   
2020 Chan MH, Chen HH, Lo YC, Wu SN. Effectiveness in the Block by Honokiol, a Dimerized Allylphenol from , of Hyperpolarization-Activated Cation Current and Delayed-Rectifier K Current. International Journal of Molecular Sciences. 21. PMID 32549398 DOI: 10.3390/ijms21124260   
2020 Hou J, Daniels PN, Burke MD. Small Molecule Channels Harness Membrane Potential to Concentrate Potassium in trk1Δtrk2Δ Yeast. Acs Chemical Biology. PMID 32427463 DOI: 10.1021/acschembio.0c00180   
2020 Zhang Y, Zhang L, Wang Y, Wang K. A Simulation Study on the Pacing and Driving of the Biological Pacemaker. Biomed Research International. 2020: 4803172. PMID 32596315 DOI: 10.1155/2020/4803172   
2020 Rohaim A, Gong L, Li J, Rui H, Blachowicz L, Roux B. Open and closed structures of a barium-blocked potassium channel. Journal of Molecular Biology. PMID 32615129 DOI: 10.1016/j.jmb.2020.06.012   
2020 Black KA, He S, Jin R, Miller DM, Bolla JR, Clarke OB, Johnson P, Windley M, Burns CJ, Hill AP, Laver D, Robinson CV, Smith BJ, Gulbis JM. A constricted opening in Kir channels does not impede potassium conduction. Nature Communications. 11: 3024. PMID 32541684 DOI: 10.1038/s41467-020-16842-0   
2020 Yang L, Pierce S, Chatterjee I, Craviso GL, Leblanc N. Paradoxical effects on voltage-gated Na+ conductance in adrenal chromaffin cells by twin vs single high intensity nanosecond electric pulses. Plos One. 15: e0234114. PMID 32516325 DOI: 10.1371/journal.pone.0234114   
2020 Zhu W, Li T, Silva JR, Chen J. Conservation and divergence in NaChBac and Na1.7 pharmacology reveals novel drug interaction mechanisms. Scientific Reports. 10: 10730. PMID 32612253 DOI: 10.1038/s41598-020-67761-5   
2020 Lee SE, Kim DH, Son SM, Choi SY, You RY, Kim CH, Choi W, Kim HS, Lim YJ, Han JY, Kim HW, Yang IJ, Xu WX, Lee SJ, Kim YC, et al. Physiological function and molecular composition of ATP-sensitive K channels in human gastric smooth muscle. Journal of Smooth Muscle Research = Nihon Heikatsukin Gakkai Kikanshi. 56: 29-45. PMID 32581184 DOI: 10.1540/jsmr.56.29   
2020 Hong S, Zou G, Kim H, Huang D, Wang P, Alshareef HN. Photothermoelectric Response of TiCT MXene Confined Ion Channels. Acs Nano. PMID 32538614 DOI: 10.1021/acsnano.0c04099   
2020 Marchal GA, Verkerk AO, Mohan RA, Wolswinkel R, Boukens BJD, Remme CA. The sodium channel Na 1.5 impacts on early murine embryonic cardiac development, structure, and function in a non-electrogenic manner. Acta Physiologica (Oxford, England). PMID 32386467 DOI: 10.1111/apha.13493   
2020 Clark MD, Contreras GF, Shen R, Perozo E. Electromechanical coupling in the hyperpolarization-activated K channel KAT1. Nature. PMID 32461693 DOI: 10.1038/s41586-020-2335-4   
2020 Collaço RC, Hyslop S, Rocha T, Dorce VAC, Rowan EG, Antunes E. Neurotoxicity of Tityus bahiensis (brown scorpion) venom in sympathetic vas deferens preparations and neuronal cells. Archives of Toxicology. PMID 32548756 DOI: 10.1007/s00204-020-02799-y   
2020 Fletcher-Taylor S, Thapa P, Sepela RJ, Kaakati R, Yarov-Yarovoy V, Sack JT, Cohen BE. Distinguishing Potassium Channel Resting State Conformations in Live Cells with Environment-Sensitive Fluorescence. Acs Chemical Neuroscience. PMID 32579336 DOI: 10.1021/acschemneuro.0c00276   
2020 Geragotelis AD, Wood ML, Göddeke H, Hong L, Webster PD, Wong EK, Freites JA, Tombola F, Tobias DJ. Voltage-dependent structural models of the human Hv1 proton channel from long-timescale molecular dynamics simulations. Proceedings of the National Academy of Sciences of the United States of America. PMID 32461356 DOI: 10.1073/pnas.1920943117   
2020 Li M, Wang XJ, Zhao Q, Wang JX, Xing HY, Zhang YZ, Zhang XX, Zhi YY, Li H, Ma J. Bufalin-induced cardiotoxicity: new findings into mechanisms. Chinese Journal of Natural Medicines. 18: 550-560. PMID 32616195 DOI: 10.1016/S1875-5364(20)30065-0   
2020 Neumaier F, Alpdogan S, Hescheler J, Schneider T. Zn2+-induced changes in Cav2.3 channel function: An electrophysiological and modeling study. The Journal of General Physiology. 152. PMID 32559275 DOI: 10.1085/jgp.202012585   
2020 Yi G, Grill WM. Kilohertz waveforms optimized to produce closed-state Na+ channel inactivation eliminate onset response in nerve conduction block. Plos Computational Biology. 16: e1007766. PMID 32542050 DOI: 10.1371/journal.pcbi.1007766   
2020 Szanto TG, Zakany F, Papp F, Varga Z, Deutsch CJ, Panyi G. The activation gate controls steady-state inactivation and recovery from inactivation in Shaker. The Journal of General Physiology. 152. PMID 32442242 DOI: 10.1085/jgp.202012591   
2020 Hernandez A, Hernández-Centeno R, Espino-Saldaña ÁE, Martínez-Torres A. HCN2 activation modulation: An electrophysiological and molecular study of the well-preserved LCI sequence in the pore channel. Archives of Biochemistry and Biophysics. 108436. PMID 32492375 DOI: 10.1016/   
2020 Nguyen HM, di Lucente J, Chen YJ, Cui Y, Ibrahim RH, Pennington MW, Jin LW, Maezawa I, Wulff H. Biophysical basis for Kv1.3 regulation of membrane potential changes induced by P2X4-mediated calcium entry in microglia. Glia. PMID 32525239 DOI: 10.1002/glia.23847   
2020 Gao S, Valinsky WC, On NC, Houlihan PR, Qu Q, Liu L, Pan X, Clapham DE, Yan N. Employing NaChBac for cryo-EM analysis of toxin action on voltage-gated Na channels in nanodisc. Proceedings of the National Academy of Sciences of the United States of America. PMID 32513729 DOI: 10.1073/pnas.1922903117   
2020 Oliveira RS, Borges BT, Leal AP, Lailowski MM, Bordon KCF, Souza VQ, Vinadé L, Santos TGD, Hyslop S, Moura S, Arantes EC, Corrado AP, Dal Belo CA. Chemical and Pharmacological Screening of (Spix 1824) Toad Parotoid Secretion in Avian Preparations. Toxins. 12. PMID 32549266 DOI: 10.3390/toxins12060396   
2020 Jackson WF. Ion channels and the regulation of myogenic tone in peripheral arterioles. Current Topics in Membranes. 85: 19-58. PMID 32402640 DOI: 10.1016/bs.ctm.2020.01.002   
2020 Mohr CJ, Schroth W, Mürdter TE, Gross D, Maier S, Stegen B, Dragoi A, Steudel FA, Stehling S, Hoppe R, Madden S, Ruth P, Huber SM, Brauch H, Lukowski R. BK channel subunits promote breast cancer development and modulate endocrine treatment response in pre-clinical models. British Journal of Pharmacology. PMID 32468618 DOI: 10.1111/bph.15147   
2020 Zybura AS, Baucum AJ, Rush AM, Cummins TR, Hudmon A. CaMKII enhances voltage-gated sodium channel Nav1.6 activity and neuronal excitability. The Journal of Biological Chemistry. PMID 32611770 DOI: 10.1074/jbc.RA120.014062   
2020 Brewer KR, Kuenze G, Vanoye CG, George AL, Meiler J, Sanders CR. Structures Illuminate Cardiac Ion Channel Functions in Health and in Long QT Syndrome. Frontiers in Pharmacology. 11: 550. PMID 32431610 DOI: 10.3389/fphar.2020.00550   
2020 Chang WT, Ragazzi E, Liu PY, Wu SN. Effective block by pirfenidone, an antifibrotic pyridone compound (5-methyl-1-phenylpyridin-2[H-1]-one), on hyperpolarization-activated cation current: An additional but distinctive target. European Journal of Pharmacology. 173237. PMID 32525005 DOI: 10.1016/j.ejphar.2020.173237   
2020 Wang D, Himaya SWA, Giacomotto J, Hasan MM, Cardoso FC, Ragnarsson L, Lewis RJ. Characterisation of d-Conotoxin TxVIA as a Mammalian T-Type Calcium Channel Modulator. Marine Drugs. 18. PMID 32629781 DOI: 10.3390/md18070343   
2020 Wang H, Li S, Wang X, He C, Wang T, Wang Y, Guo W. Vasodilation activity of dipfluzine metabolites in isolated rat basilar arteries and their underlying mechanisms. Environmental Toxicology and Pharmacology. 103430. PMID 32544426 DOI: 10.1016/j.etap.2020.103430   
2020 Zhang D, Li H, Wang Z, Emara AM, He Z. Effects of NaCl substitutes on physicochemical properties of salted pork. Meat Science. 169: 108205. PMID 32599419 DOI: 10.1016/j.meatsci.2020.108205   
2020 Zhang DM, Lin YF. Functional Modulation of Sarcolemmal K Channels by Atrial Natriuretic Peptide-Elicited Intracellular Signaling in Adult Rabbit Ventricular Cardiomyocytes. American Journal of Physiology. Cell Physiology. PMID 32432931 DOI: 10.1152/ajpcell.00409.2019   
2020 Al-Sabi A, Daly D, Rooney M, Hughes C, Kinsella GK, Kaza SK, Nolan K, Oliver Dolly J. Development of a selective inhibitor for Kv1.1 channels prevalent in demyelinated nerves. Bioorganic Chemistry. 100: 103918. PMID 32428746 DOI: 10.1016/j.bioorg.2020.103918   
2020 Marques AAM, da Silva CHF, de Souza P, de Almeida CLB, Cechinel-Filho V, Lourenço ELB, Gasparotto A. Nitric oxide and Ca-activated high-conductance K channels mediate nothofagin-induced endothelium-dependent vasodilation in the perfused rat kidney. Chemico-Biological Interactions. 109182. PMID 32554038 DOI: 10.1016/j.cbi.2020.109182   
2020 Zou X, Conrad LJ, Koschinsky K, Schlichthörl G, Preisig-Müller R, Netz E, Krüger J, Daut J, Renigunta V. The Phosphodiesterase Inhibitor IBMX Blocks the Potassium Channel THIK-1 from the Extracellular Side. Molecular Pharmacology. 98: 143-155. PMID 32616523 DOI: 10.1124/mol.120.000011   
2020 Segura-Covarrubias G, Aréchiga-Figueroa IA, De Jesús-Pérez JJ, Sánchez-Solano A, Pérez-Cornejo P, Arreola J. Voltage-Dependent Protonation of the Calcium Pocket Enable Activation of the Calcium-Activated Chloride Channel Anoctamin-1 (TMEM16A). Scientific Reports. 10: 6644. PMID 32313203 DOI: 10.1038/s41598-020-62860-9   
2020 Li B, He X, Wang P, Liu Q, Qiu W, Ma J. Opposite impacts of K and Ca on membrane fouling by humic acid and cleaning process: Evaluation and mechanism investigation. Water Research. 183: 116006. PMID 32585389 DOI: 10.1016/j.watres.2020.116006   
2020 Isaac E, Cooper SM, Jones SA, Loubani M. Do age-associated changes of voltage-gated sodium channel isoforms expressed in the mammalian heart predispose the elderly to atrial fibrillation? World Journal of Cardiology. 12: 123-135. PMID 32431783 DOI: 10.4330/wjc.v12.i4.123   
2020 Rupasinghe DB, Herzig V, Vetter I, Dekan Z, Gilchrist J, Bosmans F, Alewood PF, Lewis RJ, King GF. Mutational analysis of ProTx-I and the novel venom peptide Pe1b provide insight into residues responsible for selective inhibition of the analgesic drug target Na1.7. Biochemical Pharmacology. 114080. PMID 32511987 DOI: 10.1016/j.bcp.2020.114080   
2020 Zou X, Liu L, Xu J, Wang H, Tang WM. Few-Layered MoS2 Field-Effect Transistors with a Vertical Channel of Sub-10 nm. Acs Applied Materials & Interfaces. PMID 32610894 DOI: 10.1021/acsami.0c09060   
2020 Shin DH, Kim M, Kim Y, Jun I, Jung J, Nam JH, Cheng MH, Lee MG. Bicarbonate permeation through anion channels: its role in health and disease. Pflugers Archiv : European Journal of Physiology. PMID 32621085 DOI: 10.1007/s00424-020-02425-x   
2020 Wan Y, Liu J, Wang Y, Cheng X, Sha S, Jia W, Hu D, Li X, Guo F. [Effect of calmodulin and its mutants on binding to Na1.2 IQ]. Zhejiang Da Xue Xue Bao. Yi Xue Ban = Journal of Zhejiang University. Medical Sciences. 49: 71-75. PMID 32621420