| Year |
Citation |
Score |
| 2020 |
Zhu MJ, Shi J, Chen Y, Huang G, Zhu XW, Zhang S, Huang XF, Song GQ, Zhang HT, Ke HM, O'Donnell JM, Wang LQ, Xu Y. Phosphodiesterase 2 inhibitor Hcyb1 reverses corticosterone-induced neurotoxicity and depression-like behavior. Psychopharmacology. PMID 32926224 DOI: 10.1007/S00213-019-05401-1 |
0.347 |
|
| 2019 |
Liu N, Wang Y, An AY, Banker C, Qian Y, O'Donnell JM. Single housing-induced effects in cognitive impairment and depression-like behavior in male and female mice involve neuroplasticity related signaling. The European Journal of Neuroscience. PMID 31471985 DOI: 10.1111/ejn.14565 |
0.31 |
|
| 2019 |
Zhu X, Li W, Li Y, Xu W, Yuan Y, Zheng V, Zhang HT, O'Donnell JM, Xu Y, Yin X. The antidepressant- and anxiolytic-like effects of resveratrol: Involvement of phosphodiesterase-4D inhibition. Neuropharmacology. PMID 31026437 DOI: 10.1016/J.Neuropharm.2019.04.022 |
0.391 |
|
| 2018 |
Huang X, Xiaokaiti Y, Yang J, Pan J, Li Z, Luria V, Li Y, Song G, Zhu X, Zhang HT, O'Donnell JM, Xu Y. Inhibition of phosphodiesterase 2 reverses gp91phox oxidase-mediated depression- and anxiety-like behavior. Neuropharmacology. PMID 30268520 DOI: 10.1016/J.Neuropharm.2018.09.039 |
0.347 |
|
| 2018 |
Zhang C, Xu Y, Chowdhary A, Fox D, Gurney ME, Zhang HT, Auerbach BD, Salvi RJ, Yang M, Li G, O'Donnell JM. Memory enhancing effects of BPN14770, an allosteric inhibitor of phosphodiesterase-4D, in wild-type and humanized mice. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 30131563 DOI: 10.1038/S41386-018-0178-6 |
0.341 |
|
| 2018 |
Xu Y, Zhu N, Xu W, Ye H, Liu K, Wu F, Zhang M, Ding Y, Zhang C, Zhang H, O'Donnell J, Pan J. Inhibition of Phosphodiesterase-4 Reverses Aβ-Induced Memory Impairment by Regulation of HPA Axis Related cAMP Signaling. Frontiers in Aging Neuroscience. 10: 204. PMID 30087608 DOI: 10.3389/Fnagi.2018.00204 |
0.338 |
|
| 2018 |
Huang XF, Jiang WT, Liu L, Song FC, Zhu X, Shi GL, Ding SM, Ke HM, Wang W, O'Donnell JM, Zhang HT, Luo HB, Wan YQ, Song GQ, Xu Y. A novel PDE9 inhibitor WYQ-C36D ameliorates corticosterone-induced neurotoxicity and depression-like behaviors by cGMP-CREB-related signaling. Cns Neuroscience & Therapeutics. PMID 29722134 DOI: 10.1111/Cns.12864 |
0.301 |
|
| 2018 |
Liu L, Zheng J, Huang XF, Zhu X, Ding SM, Ke HM, O'Donnell JM, Zhang HT, Song GQ, Xu Y. The neuroprotective and antidepressant-like effects of Hcyb1, a novel selective PDE2 inhibitor. Cns Neuroscience & Therapeutics. PMID 29704309 DOI: 10.1111/Cns.12863 |
0.337 |
|
| 2017 |
Zhang C, Xu Y, Zhang HT, Gurney ME, O'Donnell JM. Comparison of the Pharmacological Profiles of Selective PDE4B and PDE4D Inhibitors in the Central Nervous System. Scientific Reports. 7: 40115. PMID 28054669 DOI: 10.1038/Srep40115 |
0.391 |
|
| 2015 |
Wang ZZ, Yang WX, Zhang Y, Zhao N, Zhang YZ, Liu YQ, Xu Y, Wilson SP, O'Donnell JM, Zhang HT, Li YF. Phosphodiesterase-4D Knock-down in the Prefrontal Cortex Alleviates Chronic Unpredictable Stress-Induced Depressive-Like Behaviors and Memory Deficits in Mice. Scientific Reports. 5: 11332. PMID 26161529 DOI: 10.1038/Srep11332 |
0.389 |
|
| 2015 |
Xu Y, Pan J, Sun J, Ding L, Ruan L, Reed M, Yu X, Klabnik J, Lin D, Li J, Chen L, Zhang C, Zhang H, O'Donnell JM. Inhibition of phosphodiesterase 2 reverses impaired cognition and neuronal remodeling caused by chronic stress. Neurobiology of Aging. 36: 955-70. PMID 25442113 DOI: 10.1016/J.Neurobiolaging.2014.08.028 |
0.343 |
|
| 2013 |
Yu Y, Wang R, Chen C, Du X, Ruan L, Sun J, Li J, Zhang L, O'Donnell JM, Pan J, Xu Y. Antidepressant-like effect of trans-resveratrol in chronic stress model: behavioral and neurochemical evidences. Journal of Psychiatric Research. 47: 315-22. PMID 23174668 DOI: 10.1016/j.jpsychires.2012.10.018 |
0.375 |
|
| 2013 |
Wang ZZ, Zhang Y, Liu YQ, Zhao N, Zhang YZ, Yuan L, An L, Li J, Wang XY, Qin JJ, Wilson SP, O'Donnell JM, Zhang HT, Li YF. RNA interference-mediated phosphodiesterase 4D splice variants knock-down in the prefrontal cortex produces antidepressant-like and cognition-enhancing effects. British Journal of Pharmacology. 168: 1001-14. PMID 23003922 DOI: 10.1111/J.1476-5381.2012.02225.X |
0.365 |
|
| 2013 |
Xu Y, Pan J, Chen L, Zhang C, Sun J, Li J, Nguyen L, Nair N, Zhang H, O'Donnell JM. Phosphodiesterase-2 inhibitor reverses corticosterone-induced neurotoxicity and related behavioural changes via cGMP/PKG dependent pathway. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 16: 835-47. PMID 22850435 DOI: 10.1017/S146114571200065X |
0.361 |
|
| 2012 |
O'Donnell JM, Xu Y. Evidence for global reduction in brain cyclic adenosine monophosphate signaling in depression. Biological Psychiatry. 72: 524-5. PMID 22959119 DOI: 10.1016/j.biopsych.2012.07.017 |
0.348 |
|
| 2011 |
Xiao L, O'Callaghan JP, O'Donnell JM. Effects of repeated treatment with phosphodiesterase-4 inhibitors on cAMP signaling, hippocampal cell proliferation, and behavior in the forced-swim test. The Journal of Pharmacology and Experimental Therapeutics. 338: 641-7. PMID 21566211 DOI: 10.1124/jpet.111.179358 |
0.407 |
|
| 2011 |
Xu Y, Zhang C, Wang R, Govindarajan SS, Barish PA, Vernon MM, Fu C, Acharya AP, Chen L, Boykin E, Yu J, Pan J, O'Donnell JM, Ogle WO. Corticosterone induced morphological changes of hippocampal and amygdaloid cell lines are dependent on 5-HT7 receptor related signal pathway. Neuroscience. 182: 71-81. PMID 21371532 DOI: 10.1016/J.Neuroscience.2011.02.042 |
0.301 |
|
| 2011 |
Li YF, Cheng YF, Huang Y, Conti M, Wilson SP, O'Donnell JM, Zhang HT. Phosphodiesterase-4D knock-out and RNA interference-mediated knock-down enhance memory and increase hippocampal neurogenesis via increased cAMP signaling. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 172-83. PMID 21209202 DOI: 10.1523/Jneurosci.5236-10.2011 |
0.332 |
|
| 2009 |
Masood A, Huang Y, Hajjhussein H, Xiao L, Li H, Wang W, Hamza A, Zhan CG, O'Donnell JM. Anxiolytic effects of phosphodiesterase-2 inhibitors associated with increased cGMP signaling. The Journal of Pharmacology and Experimental Therapeutics. 331: 690-9. PMID 19684253 DOI: 10.1124/jpet.109.156729 |
0.395 |
|
| 2009 |
Li YF, Huang Y, Amsdell SL, Xiao L, O'Donnell JM, Zhang HT. Antidepressant- and anxiolytic-like effects of the phosphodiesterase-4 inhibitor rolipram on behavior depend on cyclic AMP response element binding protein-mediated neurogenesis in the hippocampus. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 34: 2404-19. PMID 19516250 DOI: 10.1038/Npp.2009.66 |
0.394 |
|
| 2009 |
Zhang HT, Whisler LR, Huang Y, Xiang Y, O'Donnell JM. Postsynaptic alpha-2 adrenergic receptors are critical for the antidepressant-like effects of desipramine on behavior. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 34: 1067-77. PMID 18923403 DOI: 10.1038/npp.2008.184 |
0.4 |
|
| 2009 |
Zhao Z, Zhang HT, Bootzin E, Millan MJ, O'Donnell JM. Association of changes in norepinephrine and serotonin transporter expression with the long-term behavioral effects of antidepressant drugs. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 34: 1467-81. PMID 18923402 DOI: 10.1038/Npp.2008.183 |
0.549 |
|
| 2008 |
Masood A, Nadeem A, Mustafa SJ, O'Donnell JM. Reversal of oxidative stress-induced anxiety by inhibition of phosphodiesterase-2 in mice. The Journal of Pharmacology and Experimental Therapeutics. 326: 369-79. PMID 18456873 DOI: 10.1124/jpet.108.137208 |
0.327 |
|
| 2008 |
Zhao Z, Baros AM, Zhang HT, Lapiz MD, Bondi CO, Morilak DA, O'Donnell JM. Norepinephrine transporter regulation mediates the long-term behavioral effects of the antidepressant desipramine. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 33: 3190-200. PMID 18418364 DOI: 10.1038/Npp.2008.45 |
0.572 |
|
| 2008 |
Dlaboga D, Hajjhussein H, O'Donnell JM. Chronic haloperidol and clozapine produce different patterns of effects on phosphodiesterase-1B, -4B, and -10A expression in rat striatum. Neuropharmacology. 54: 745-54. PMID 18222493 DOI: 10.1016/j.neuropharm.2007.12.002 |
0.339 |
|
| 2008 |
Zhang HT, Huang Y, Masood A, Stolinski LR, Li Y, Zhang L, Dlaboga D, Jin SL, Conti M, O'Donnell JM. Anxiogenic-like behavioral phenotype of mice deficient in phosphodiesterase 4B (PDE4B). Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 33: 1611-23. PMID 17700644 DOI: 10.1038/Sj.Npp.1301537 |
0.332 |
|
| 2007 |
Lapiz MD, Zhao Z, Bondi CO, O'Donnell JM, Morilak DA. Blockade of autoreceptor-mediated inhibition of norepinephrine release by atipamezole is maintained after chronic reuptake inhibition. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 10: 827-33. PMID 17697440 DOI: 10.1017/S1461145707007651 |
0.534 |
|
| 2007 |
Hajjhussein H, Suvarna NU, Gremillion C, Chandler LJ, O'Donnell JM. Changes in NMDA receptor-induced cyclic nucleotide synthesis regulate the age-dependent increase in PDE4A expression in primary cortical cultures. Brain Research. 1149: 58-68. PMID 17407767 DOI: 10.1016/j.brainres.2007.02.090 |
0.339 |
|
| 2006 |
Dlaboga D, Hajjhussein H, O'Donnell JM. Regulation of phosphodiesterase-4 (PDE4) expression in mouse brain by repeated antidepressant treatment: comparison with rolipram. Brain Research. 1096: 104-12. PMID 16730340 DOI: 10.1016/j.brainres.2006.04.032 |
0.415 |
|
| 2005 |
Zhang HT, Huang Y, Mishler K, Roerig SC, O'Donnell JM. Interaction between the antidepressant-like behavioral effects of beta adrenergic agonists and the cyclic AMP PDE inhibitor rolipram in rats. Psychopharmacology. 182: 104-15. PMID 16010541 DOI: 10.1007/s00213-005-0055-y |
0.396 |
|
| 2005 |
O'Donnell JM, Marek GJ, Seiden LS. Antidepressant effects assessed using behavior maintained under a differential-reinforcement-of-low-rate (DRL) operant schedule. Neuroscience and Biobehavioral Reviews. 29: 785-98. PMID 15893376 DOI: 10.1016/j.neubiorev.2005.03.018 |
0.396 |
|
| 2004 |
Zhang HT, Zhao Y, Huang Y, Dorairaj NR, Chandler LJ, O'Donnell JM. Inhibition of the phosphodiesterase 4 (PDE4) enzyme reverses memory deficits produced by infusion of the MEK inhibitor U0126 into the CA1 subregion of the rat hippocampus. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 29: 1432-9. PMID 15114341 DOI: 10.1038/sj.npp.1300440 |
0.356 |
|
| 2004 |
O'Donnell JM, Zhang HT. Antidepressant effects of inhibitors of cAMP phosphodiesterase (PDE4). Trends in Pharmacological Sciences. 25: 158-63. PMID 15019272 DOI: 10.1016/j.tips.2004.01.003 |
0.336 |
|
| 2003 |
O'Donnell J, Stemmelin J, Nitta A, Brouillette J, Quirion R. Gene expression profiling following chronic NMDA receptor blockade-induced learning deficits in rats. Synapse (New York, N.Y.). 50: 171-80. PMID 14515334 DOI: 10.1002/Syn.10258 |
0.34 |
|
| 2003 |
Zhao Y, Zhang HT, O'Donnell JM. Antidepressant-induced increase in high-affinity rolipram binding sites in rat brain: dependence on noradrenergic and serotonergic function. The Journal of Pharmacology and Experimental Therapeutics. 307: 246-53. PMID 12954819 DOI: 10.1124/Jpet.103.053215 |
0.355 |
|
| 2003 |
Zhang HT, Huang Y, O'Donnell JM. Antagonism of the antidepressant-like effects of clenbuterol by central administration of beta-adrenergic antagonists in rats. Psychopharmacology. 170: 102-7. PMID 12898120 DOI: 10.1007/s00213-003-1512-0 |
0.425 |
|
| 2002 |
Zhang HT, Huang Y, Jin SL, Frith SA, Suvarna N, Conti M, O'Donnell JM. Antidepressant-like profile and reduced sensitivity to rolipram in mice deficient in the PDE4D phosphodiesterase enzyme. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 27: 587-95. PMID 12377395 DOI: 10.1016/S0893-133X(02)00344-5 |
0.372 |
|
| 2002 |
Crissman AM, O'Donnell JM. Effects of antidepressants in rats trained to discriminate centrally administered isoproterenol. The Journal of Pharmacology and Experimental Therapeutics. 302: 606-11. PMID 12130722 DOI: 10.1124/jpet.102.034686 |
0.366 |
|
| 2002 |
Suvarna NU, O'Donnell JM. Hydrolysis of N-methyl-D-aspartate receptor-stimulated cAMP and cGMP by PDE4 and PDE2 phosphodiesterases in primary neuronal cultures of rat cerebral cortex and hippocampus. The Journal of Pharmacology and Experimental Therapeutics. 302: 249-56. PMID 12065724 DOI: 10.1124/Jpet.302.1.249 |
0.341 |
|
| 2001 |
Zhang HT, Frith SA, Wilkins J, O'Donnell JM. Comparison of the effects of isoproterenol administered into the hippocampus, frontal cortex, or amygdala on behavior of rats maintained by differential reinforcement of low response rate. Psychopharmacology. 159: 89-97. PMID 11797075 DOI: 10.1007/s002130100889 |
0.416 |
|
| 2001 |
Makhay MM, Houslay MD, O'Donnell JM. Discriminative stimulus effects of the type-4 phosphodiesterase inhibitor rolipram in rats. Psychopharmacology. 158: 297-304. PMID 11713620 DOI: 10.1007/s002130100878 |
0.402 |
|
| 2001 |
Farooqui SM, Al-Bagdadi F, Houslay MD, Bolger GB, Stout R, Specian RD, Cherry JA, Conti M, O'Donnell JM. Surgically induced cryptorchidism-related degenerative changes in spermatogonia are associated with loss of cyclic adenosine monophosphate-dependent phosphodiesterases type 4 in abdominal testes of rats. Biology of Reproduction. 64: 1583-9. PMID 11369582 DOI: 10.1095/Biolreprod64.6.1583 |
0.321 |
|
| 2001 |
Crissman AM, Makhay MM, O'Donnell JM. Discriminative stimulus effects of centrally administered isoproterenol in rats: mediation by beta-1 adrenergic receptors. Psychopharmacology. 154: 70-5. PMID 11292008 DOI: 10.1007/S002130000618 |
0.39 |
|
| 2000 |
Zhang HT, O'Donnell JM. Effects of rolipram on scopolamine-induced impairment of working and reference memory in the radial-arm maze tests in rats. Psychopharmacology. 150: 311-6. PMID 10923759 DOI: 10.1007/s002130000414 |
0.303 |
|
| 2000 |
Zavecz JH, Bueno O, Maloney RE, O'Donnell JM, Roerig SC, Battarbee HD. Cardiac excitation-contraction coupling in the portal hypertensive rat. American Journal of Physiology. Gastrointestinal and Liver Physiology. 279: G28-39. PMID 10898744 DOI: 10.1152/Ajpgi.2000.279.1.G28 |
0.304 |
|
| 2000 |
Zhang HT, Crissman AM, Dorairaj NR, Chandler LJ, O'Donnell JM. Inhibition of cyclic AMP phosphodiesterase (PDE4) reverses memory deficits associated with NMDA receptor antagonism. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 23: 198-204. PMID 10882846 DOI: 10.1016/S0893-133X(00)00108-1 |
0.366 |
|
| 2000 |
Ye Y, Jackson K, O'Donnell JM. Effects of repeated antidepressant treatment of type 4A phosphodiesterase (PDE4A) in rat brain. Journal of Neurochemistry. 74: 1257-62. PMID 10693959 DOI: 10.1046/J.1471-4159.2000.741257.X |
0.416 |
|
| 1997 |
Ye Y, Conti M, Houslay MD, Farooqui SM, Chen M, O'Donnell JM. Noradrenergic activity differentially regulates the expression of rolipram-sensitive, high-affinity cyclic AMP phosphodiesterase (PDE4) in rat brain. Journal of Neurochemistry. 69: 2397-404. PMID 9375671 DOI: 10.1046/J.1471-4159.1997.69062397.X |
0.358 |
|
| 1996 |
Ye Y, O'Donnell JM. Diminished noradrenergic stimulation reduces the activity of rolipram-sensitive, high-affinity cyclic AMP phosphodiesterase in rat cerebral cortex. Journal of Neurochemistry. 66: 1894-902. PMID 8780016 DOI: 10.1046/J.1471-4159.1996.66051894.X |
0.425 |
|
| 1995 |
Zavecz JH, Battarbee HD, O'Donnell JM. Cardiac beta-adrenoceptor-effector coupling in portal vein-stenosed rats. The American Journal of Physiology. 268: G410-5. PMID 7900802 DOI: 10.1152/Ajpgi.1995.268.3.G410 |
0.359 |
|
| 1995 |
Murugaiah KD, O'Donnell JM. Facilitation of noradrenaline release from rat brain slices by beta-adrenoceptors. Naunyn-Schmiedeberg's Archives of Pharmacology. 351: 483-90. PMID 7643911 DOI: 10.1007/Bf00171039 |
0.372 |
|
| 1995 |
Murugaiah KD, O'Donnell JM. Facilitation of norepinephrine release from cerebral cortex is mediated by beta 2-adrenergic receptors. Life Sciences. 57: PL327-32. PMID 7475928 DOI: 10.1016/0024-3205(95)02173-G |
0.312 |
|
| 1993 |
O'Donnell JM. Effects of the beta-2 adrenergic agonist zinterol on DRL behavior and locomotor activity. Psychopharmacology. 113: 89-94. PMID 7862834 DOI: 10.1007/Bf02244339 |
0.408 |
|
| 1993 |
O'Donnell JM. Differential sensitivity to the effects of albuterol on locomotor activity and operant behavior. Psychopharmacology. 113: 243-9. PMID 7855189 DOI: 10.1007/Bf02245705 |
0.378 |
|
| 1989 |
McElroy JF, Stimmel JJ, O'Donnell JM. Effects of centrally acting beta adrenergic agonists on discrete trial conditioned avoidance behavior in rats. Psychopharmacology. 97: 108-14. PMID 2565587 DOI: 10.1007/Bf00443423 |
0.372 |
|
| 1988 |
Fowler JC, O'Donnell JM. Antagonism of the responses to isoproterenol in the rat hippocampal slice with subtype-selective antagonists. European Journal of Pharmacology. 153: 105-10. PMID 2905663 DOI: 10.1016/0014-2999(88)90593-6 |
0.357 |
|
| 1988 |
O'Donnell JM. Behavioral consequences of activation of beta adrenergic receptors by clenbuterol: evidence for mediation by the central nervous system. Brain Research Bulletin. 21: 491-7. PMID 2850845 DOI: 10.1016/0361-9230(88)90164-5 |
0.404 |
|
| 1987 |
Ordway GA, O'Donnell JM, Frazer A. Effects of clenbuterol on central beta-1 and beta-2 adrenergic receptors of the rat. The Journal of Pharmacology and Experimental Therapeutics. 241: 187-95. PMID 3033200 |
0.63 |
|
| 1985 |
O'Donnell JM, Seiden LS. Effect of the experimental antidepressant AHR-9377 on performance during differential reinforcement of low response rate. Psychopharmacology. 87: 283-5. PMID 3936083 DOI: 10.1007/BF00432708 |
0.326 |
|
| 1985 |
O'Donnell JM, Frazer A. Effects of clenbuterol and antidepressant drugs on beta adrenergic receptor/N-protein coupling in the cerebral cortex of the rat. The Journal of Pharmacology and Experimental Therapeutics. 234: 30-6. PMID 2989510 |
0.515 |
|
| 1984 |
O'Donnell JM, Wolfe BB, Frazer A. Agonist interactions with beta adrenergic receptors in rat brain. The Journal of Pharmacology and Experimental Therapeutics. 228: 640-7. PMID 6142940 |
0.502 |
|
| 1982 |
O'Donnell JM, Seiden LS. Effects of monoamine oxidase inhibitors on performance during differential reinforcement of low response rate. Psychopharmacology. 78: 214-8. PMID 6818577 DOI: 10.1007/BF00428153 |
0.325 |
|
| 1982 |
O'Donnell JM, Rider DP, Somani S, Seiden LS. The effect of repeated desipramine administration on water intake in rats. Psychopharmacology. 77: 129-33. PMID 6812130 DOI: 10.1007/BF00431934 |
0.308 |
|
| 1980 |
O'Donnell JM, Miczek KA. No tolerance to antiaggressive effect of d-amphetamine in mice. Psychopharmacology. 68: 191-6. PMID 6776565 DOI: 10.1007/Bf00432140 |
0.319 |
|
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