James T. Auman, Ph.D. - Publications

2002 Duke University, Durham, NC 
Pharmacology, Toxicology

34 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 . Comprehensive genomic characterization of head and neck squamous cell carcinomas. Nature. 517: 576-82. PMID 25631445 DOI: 10.1038/nature14129  1
2015 Abeshouse A, Ahn J, Akbani R, Ally A, Amin S, Andry CD, Annala M, Aprikian A, Armenia J, Arora A, Auman JT, Balasundaram M, Balu S, Barbieri CE, Bauer T, et al. The Molecular Taxonomy of Primary Prostate Cancer Cell. 163: 1011-1025. DOI: 10.1016/j.cell.2015.10.025  1
2015 Akbani R, Akdemir KC, Aksoy BA, Albert M, Ally A, Amin SB, Arachchi H, Arora A, Auman JT, Ayala B, Baboud J, Balasundaram M, Balu S, Barnabas N, Bartlett J, et al. Genomic Classification of Cutaneous Melanoma Cell. 161: 1681-1696. DOI: 10.1016/j.cell.2015.05.044  1
2014 . Integrated genomic characterization of papillary thyroid carcinoma. Cell. 159: 676-90. PMID 25417114 DOI: 10.1016/j.cell.2014.09.050  1
2013 Weinstein JN, Collisson EA, Mills GB, Shaw KR, Ozenberger BA, Ellrott K, Shmulevich I, Sander C, Stuart JM. The Cancer Genome Atlas Pan-Cancer analysis project. Nature Genetics. 45: 1113-20. PMID 24071849 DOI: 10.1038/ng.2764  1
2013 Wang P, Dong Q, Zhang C, Kuan PF, Liu Y, Jeck WR, Andersen JB, Jiang W, Savich GL, Tan TX, Auman JT, Hoskins JM, Misher AD, Moser CD, Yourstone SM, et al. Mutations in isocitrate dehydrogenase 1 and 2 occur frequently in intrahepatic cholangiocarcinomas and share hypermethylation targets with glioblastomas. Oncogene. 32: 3091-100. PMID 22824796 DOI: 10.1038/onc.2012.315  1
2012 Brown CC, Havener TM, Medina MW, Auman JT, Mangravite LM, Krauss RM, McLeod HL, Motsinger-Reif AA. A genome-wide association analysis of temozolomide response using lymphoblastoid cell lines shows a clinically relevant association with MGMT. Pharmacogenetics and Genomics. 22: 796-802. PMID 23047291 DOI: 10.1097/FPC.0b013e3283589c50  1
2012 Koboldt DC, Fulton RS, McLellan MD, Schmidt H, Kalicki-Veizer J, McMichael JF, Fulton LL, Dooling DJ, Ding L, Mardis ER, Wilson RK, Ally A, Balasundaram M, Butterfield YSN, Carlsen R, ... ... Auman JT, et al. Comprehensive molecular portraits of human breast tumours Nature. 490: 61-70. DOI: 10.1038/nature11412  1
2011 Cui Y, Huang Q, Auman JT, Knight B, Jin X, Blanchard KT, Chou J, Jayadev S, Paules RS. Genomic-derived markers for early detection of calcineurin inhibitor immunosuppressant-mediated nephrotoxicity. Toxicological Sciences : An Official Journal of the Society of Toxicology. 124: 23-34. PMID 21865292 DOI: 10.1093/toxsci/kfr217  1
2011 Watson VG, Motsinger-Reif A, Hardison NE, Peters EJ, Havener TM, Everitt L, Auman JT, Comins DL, McLeod HL. Identification and replication of loci involved in camptothecin-induced cytotoxicity using CEPH pedigrees. Plos One. 6: e17561. PMID 21573211 DOI: 10.1371/journal.pone.0017561  1
2010 Auman JT. Gene therapy: Have the risks associated with viral vectors been solved? Current Opinion in Molecular Therapeutics. 12: 637-638. PMID 21280375  1
2010 Watson RG, Muhale F, Thorne LB, Yu J, O'Neil BH, Hoskins JM, Meyers MO, Deal AM, Ibrahim JG, Hudson ML, Walko CM, McLeod HL, Auman JT. Amplification of thymidylate synthetase in metastatic colorectal cancer patients pretreated with 5-fluorouracil-based chemotherapy. European Journal of Cancer (Oxford, England : 1990). 46: 3358-64. PMID 20727737 DOI: 10.1016/j.ejca.2010.07.011  1
2010 Auman JT. Editorial: Cancer pharmacogenomics: Do cancer cell lines have the right stuff? Pharmacogenomics. 11: 1035-1037. PMID 20712522 DOI: 10.2217/pgs.10.107  1
2010 Auman JT, McLeod HL. Colorectal cancer cell lines lack the molecular heterogeneity of clinical colorectal tumors. Clinical Colorectal Cancer. 9: 40-7. PMID 20100687 DOI: 10.3816/CCC.2010.n.005  1
2010 Auman JT, McLeod HL. Now's the time to find biomarkers on purpose Annals of Oncology. 21: 193-194. PMID 20047974 DOI: 10.1093/annonc/mdp571  1
2010 Rakhra-Burris TK, Auman JT, Deverka P, Dressler LG, Evans JP, Goldberg RM, Havener TM, Hoskins JM, Jonas DE, Long KM, Motsinger-Reif AA, Irvin WJ, Richards KL, Roederer MW, Valgus JM, et al. Institutional profile. UNC Institute for Pharmacogenomics and Individualized Therapy: interdisciplinary research for individual care. Pharmacogenomics. 11: 13-21. PMID 20017668 DOI: 10.2217/pgs.09.167  1
2008 Auman JT, McLeod HL. Applications of genomic tools to colorectal cancer therapeutics Current Opinion in Molecular Therapeutics. 10: 548-554. PMID 19051132  1
2008 Yen-Revollo JL, Auman JT, McLeod HL. Race does not explain genetic heterogeneity in pharmacogenomic pathways Pharmacogenomics. 9: 1639-1645. PMID 19018720 DOI: 10.2217/14622416.9.11.1639  1
2008 Auman JT, Church R, Lee SY, Watson MA, Fleshman JW, Mcleod HL. Celecoxib pre-treatment in human colorectal adenocarcinoma patients is associated with gene expression alterations suggestive of diminished cellular proliferation. European Journal of Cancer (Oxford, England : 1990). 44: 1754-60. PMID 18653328 DOI: 10.1016/j.ejca.2008.05.010  1
2008 Lobenhofer EK, Auman JT, Blackshear PE, Boorman GA, Bushel PR, Cunningham ML, Fostel JM, Gerrish K, Heinloth AN, Irwin RD, Malarkey DE, Merrick BA, Sieber SO, Tucker CJ, Ward SM, et al. Gene expression response in target organ and whole blood varies as a function of target organ injury phenotype. Genome Biology. 9: R100. PMID 18570634 DOI: 10.1186/gb-2008-9-6-r100  1
2008 Auman JT, McLeod HL. Cancer pharmacogenomics: DNA genotyping and gene expression profiling to identify molecular determinants of chemosensitivity Drug Metabolism Reviews. 40: 303-315. PMID 18464047 DOI: 10.1080/03602530801952427  1
2007 Auman JT, Boorman GA, Wilson RE, Travlos GS, Paules RS. Heat map visualization of high-density clinical chemistry data. Physiological Genomics. 31: 352-6. PMID 17652165 DOI: 10.1152/physiolgenomics.00276.2006  1
2007 Auman JT, Chou J, Gerrish K, Huang Q, Jayadev S, Blanchard K, Paules RS. Identification of genes implicated in methapyrilene-induced hepatotoxicity by comparing differential gene expression in target and nontarget tissue. Environmental Health Perspectives. 115: 572-8. PMID 17450226 DOI: 10.1289/ehp.9396  1
2005 Fannin RD, Auman JT, Bruno ME, Sieber SO, Ward SM, Tucker CJ, Merrick BA, Paules RS. Differential gene expression profiling in whole blood during acute systemic inflammation in lipopolysaccharide-treated rats. Physiological Genomics. 21: 92-104. PMID 15781589 DOI: 10.1152/physiolgenomics.00190.2004  1
2003 Slotkin TA, Auman JT, Seidler FJ. Ontogenesis of beta-adrenoceptor signaling: implications for perinatal physiology and for fetal effects of tocolytic drugs. The Journal of Pharmacology and Experimental Therapeutics. 306: 1-7. PMID 12682213 DOI: 10.1124/jpet.102.048421  1
2002 Auman JT, Seidler FJ, Slotkin TA. Beta-adrenoceptor control of G protein function in the neonate: determinant of desensitization or sensitization. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 283: R1236-44. PMID 12376418 DOI: 10.1152/ajpregu.00409.2002  1
2002 Auman JT, Seidler FJ, Tate CA, Slotkin TA. Are developing beta-adrenoceptors able to desensitize? Acute and chronic effects of beta-agonists in neonatal heart and liver. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 283: R205-17. PMID 12069947 DOI: 10.1152/ajpregu.00122.2002  1
2002 Garofolo MC, Seidler FJ, Auman JT, Slotkin TA. beta-Adrenergic modulation of muscarinic cholinergic receptor expression and function in developing heart. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 282: R1356-63. PMID 11959676 DOI: 10.1152/ajpregu.00598.2001  1
2002 Slotkin TA, Pinkerton KE, Auman JT, Qiao D, Seidler FJ. Perinatal exposure to environmental tobacco smoke upregulates nicotinic cholinergic receptors in monkey brain. Brain Research. Developmental Brain Research. 133: 175-9. PMID 11882347  1
2001 Auman JT, Seidler FJ, Tate CA, Slotkin TA. Beta-adrenoceptor-mediated cell signaling in the neonatal heart and liver: responses to terbutaline. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 281: R1895-901. PMID 11705775  1
2001 Auman JT, Seidler FJ, Slotkin TA. Regulation of fetal cardiac and hepatic beta-adrenoceptors and adenylyl cyclase signaling: terbutaline effects. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 281: R1079-89. PMID 11557613  1
2001 Slotkin TA, Pinkerton KE, Garofolo MC, Auman JT, McCook EC, Seidler FJ. Perinatal exposure to environmental tobacco smoke induces adenylyl cyclase and alters receptor-mediated cell signaling in brain and heart of neonatal rats. Brain Research. 898: 73-81. PMID 11292450 DOI: 10.1016/S0006-8993(01)02145-X  1
2000 Auman JT, Seidler FJ, Slotkin TA. Neonatal chlorpyrifos exposure targets multiple proteins governing the hepatic adenylyl cyclase signaling cascade: implications for neurotoxicity. Brain Research. Developmental Brain Research. 121: 19-27. PMID 10837889 DOI: 10.1016/S0165-3806(00)00021-3  1
1994 Levin ED, Briggs SJ, Christopher NC, Auman JT. Working memory performance and cholinergic effects in the ventral tegmental area and substantia nigra. Brain Research. 657: 165-70. PMID 7820615 DOI: 10.1016/0006-8993(94)90964-4  1
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