| Year |
Citation |
Score |
| 2013 |
Yuzefovych LV, LeDoux SP, Wilson GL, Rachek LI. Mitochondrial DNA damage via augmented oxidative stress regulates endoplasmic reticulum stress and autophagy: Crosstalk, links and signaling Plos One. 8. PMID 24349491 DOI: 10.1371/Journal.Pone.0083349 |
0.518 |
|
| 2013 |
Yuzefovych LV, Schuler AM, Chen J, Alvarez DF, Eide L, LeDoux SP, Wilson GL, Rachek LI. Alteration of mitochondrial function and insulin sensitivity in primary mouse skeletal muscle cells isolated from transgenic and knockout mice: Role of OGG1 Endocrinology. 154: 2640-2649. PMID 23748360 DOI: 10.1210/En.2013-1076 |
0.521 |
|
| 2013 |
Alexeyev M, Shokolenko I, Wilson G, LeDoux S. The maintenance of mitochondrial DNA integrity--critical analysis and update. Cold Spring Harbor Perspectives in Biology. 5: a012641. PMID 23637283 DOI: 10.1101/Cshperspect.A012641 |
0.618 |
|
| 2013 |
Yuzefovych LV, LeDoux SP, Wilson GL, Rachek LI. A schematic model of the proposed links between palmitate-induced mtDNA damage, mitochondrial dysfunction and ROS production, ER stress, autophagy and IR in L6 myotubes. Plos One. DOI: 10.1371/Journal.Pone.0083349.G004 |
0.414 |
|
| 2012 |
Ding Y, Liu Z, Desai S, Zhao Y, Liu H, Pannell LK, Yi H, Wright ER, Owen LB, Dean-Colomb W, Fodstad O, Lu J, Ledoux SP, Wilson GL, Tan M. Receptor tyrosine kinase ErbB2 translocates into mitochondria and regulates cellular metabolism Nature Communications. 3. PMID 23232401 DOI: 10.1038/Ncomms2236 |
0.395 |
|
| 2010 |
Lozano J, Muñoz P, Nore BF, Ledoux S, Segura-Aguilar J. Stable expression of short interfering RNA for DT-diaphorase induces neurotoxicity. Chemical Research in Toxicology. 23: 1492-6. PMID 20849151 DOI: 10.1021/Tx100182A |
0.314 |
|
| 2010 |
Shokolenko IN, Alexeyev MF, Ledoux SP, Wilson GL. The approaches for manipulating mitochondrial proteome Environmental and Molecular Mutagenesis. 51: 451-461. PMID 20544885 DOI: 10.1002/Em.20570 |
0.422 |
|
| 2009 |
Koczor CA, Shokolenko IN, Boyd AK, Balk SP, Wilson GL, LeDoux SP. Mitochondrial DNA damage initiates a cell cycle arrest by a Chk2-associated mechanism in mammalian cells Journal of Biological Chemistry. 284: 36191-36201. PMID 19840931 DOI: 10.1074/Jbc.M109.036020 |
0.572 |
|
| 2009 |
Rachek LI, Yuzefovych LV, LeDoux SP, Julie NL, Wilson GL. Troglitazone, but not rosiglitazone, damages mitochondrial DNA and induces mitochondrial dysfunction and cell death in human hepatocytes Toxicology and Applied Pharmacology. 240: 348-354. PMID 19632256 DOI: 10.1016/J.Taap.2009.07.021 |
0.575 |
|
| 2009 |
Koczor CA, Snyder JW, Shokolenko IN, Dobson AW, Wilson GL, Ledoux SP. Targeting repair proteins to the mitochondria of mammalian cells through stable transfection, transient transfection, viral transduction, and TAT-mediated protein transduction. Methods in Molecular Biology (Clifton, N.J.). 554: 233-249. PMID 19513678 DOI: 10.1007/978-1-59745-521-3_15 |
0.555 |
|
| 2009 |
Paris I, Perez-Pastene C, Couve E, Caviedes P, Ledoux S, Segura-Aguilar J. Copper dopamine complex induces mitochondrial autophagy preceding caspase-independent apoptotic cell death. The Journal of Biological Chemistry. 284: 13306-15. PMID 19265190 DOI: 10.1074/Jbc.M900323200 |
0.464 |
|
| 2009 |
Koczor C, Shokolenko I, Wilson G, LeDoux S. 49. Modulating Mitochondrial Base Excision Repair to Alter Cell Cycle Progression Mitochondrion. 9: 73. DOI: 10.1016/J.Mito.2008.12.043 |
0.516 |
|
| 2008 |
Druzhyna NM, Wilson GL, LeDoux SP. Mitochondrial DNA repair in aging and disease Mechanisms of Ageing and Development. 129: 383-390. PMID 18417187 DOI: 10.1016/J.Mad.2008.03.002 |
0.616 |
|
| 2007 |
Harrison JF, Rinne ML, Kelley MR, Druzhyna NM, Wilson GL, Ledoux SP. Altering DNA base excision repair: use of nuclear and mitochondrial-targeted N-methylpurine DNA glycosylase to sensitize astroglia to chemotherapeutic agents. Glia. 55: 1416-25. PMID 17674369 DOI: 10.1002/Glia.20556 |
0.621 |
|
| 2007 |
Ho R, Rachek LI, Xu Y, Kelley MR, LeDoux SP, Wilson GL. Yeast apurinic/apyrimidinic endonuclease Apn1 protects mammalian neuronal cell line from oxidative stress Journal of Neurochemistry. 102: 13-24. PMID 17506861 DOI: 10.1111/J.1471-4159.2007.04490.X |
0.625 |
|
| 2007 |
LeDoux SP, Druzhyna NM, Hollensworth SB, Harrison JF, Wilson GL. Mitochondrial DNA repair: a critical player in the response of cells of the CNS to genotoxic insults. Neuroscience. 145: 1249-59. PMID 17097236 DOI: 10.1016/J.Neuroscience.2006.10.002 |
0.682 |
|
| 2007 |
Rachek LI, Musiyenko SI, LeDoux SP, Wilson GL. Palmitate induced mitochondrial deoxyribonucleic acid damage and apoptosis in L6 rat skeletal muscle cells Endocrinology. 148: 293-299. PMID 17023529 DOI: 10.1210/En.2006-0998 |
0.489 |
|
| 2006 |
Rachek LI, Thornley NP, Grishko VI, LeDoux SP, Wilson GL. Protection of INS-1 cells from free fatty acid-induced apoptosis by targeting hOGG1 to mitochondria Diabetes. 55: 1022-1028. PMID 16567524 DOI: 10.2337/Diabetes.55.04.06.Db05-0865 |
0.568 |
|
| 2006 |
Rachek LI, Grishko VI, LeDoux SP, Wilson GL. Role of nitric oxide-induced mtDNA damage in mitochondrial dysfunction and apoptosis Free Radical Biology and Medicine. 40: 754-762. PMID 16520228 DOI: 10.1016/J.Freeradbiomed.2005.09.028 |
0.649 |
|
| 2006 |
Alexeyev MF, LeDoux SP, Wilson GL. Mitochondrial DNA and Aging Handbook of Models For Human Aging. 507-519. DOI: 10.1016/B978-012369391-4/50042-4 |
0.444 |
|
| 2005 |
Harrison JF, Hollensworth SB, Spitz DR, Copeland WC, Wilson GL, LeDoux SP. Oxidative stress-induced apoptosis in neurons correlates with mitochondrial DNA base excision repair pathway imbalance. Nucleic Acids Research. 33: 4660-71. PMID 16107556 DOI: 10.1093/Nar/Gki759 |
0.589 |
|
| 2005 |
Druzhyna NM, Musiyenko SI, Wilson GL, LeDoux SP. Cytokines induce nitric oxide-mediated mtDNA damage and apoptosis in oligodendrocytes. Protective role of targeting 8-oxoguanine glycosylase to mitochondria. The Journal of Biological Chemistry. 280: 21673-9. PMID 15811855 DOI: 10.1074/Jbc.M411531200 |
0.569 |
|
| 2005 |
Shokolenko IN, Alexeyev MF, LeDoux SP, Wilson GL. TAT-mediated protein transduction and targeted delivery of fusion proteins into mitochondria of breast cancer cells. Dna Repair. 4: 511-8. PMID 15725631 DOI: 10.1016/J.Dnarep.2004.11.009 |
0.423 |
|
| 2005 |
Grishko V, Rachek L, Musiyenko S, Ledoux SP, Wilson GL. Involvement of mtDNA damage in free fatty acid-induced apoptosis. Free Radical Biology & Medicine. 38: 755-62. PMID 15721986 DOI: 10.1016/J.Freeradbiomed.2004.11.023 |
0.546 |
|
| 2005 |
Grishko VI, Rachek LI, Spitz DR, Wilson GL, LeDoux SP. Contribution of mitochondrial DNA repair to cell resistance from oxidative stress. The Journal of Biological Chemistry. 280: 8901-5. PMID 15632148 DOI: 10.1074/Jbc.M413022200 |
0.602 |
|
| 2005 |
Ruchko M, Gorodnya O, LeDoux SP, Alexeyev MF, Al-Mehdi AB, Gillespie MN. Mitochondrial DNA damage triggers mitochondrial dysfunction and apoptosis in oxidant-challenged lung endothelial cells. American Journal of Physiology. Lung Cellular and Molecular Physiology. 288: L530-5. PMID 15563690 DOI: 10.1152/Ajplung.00255.2004 |
0.587 |
|
| 2005 |
Druzhyna NM, Musiyenko SI, Wilson GL, LeDoux SP. Cytokines induce nitric oxide-mediated mtDNA damage and apoptosis in oligodendrocytes: Protective role of targeting 8-oxoguanine glycosylase to mitochondria Journal of Biological Chemistry. 280: 21673-21679. DOI: 10.1074/jbc.M411531200 |
0.394 |
|
| 2004 |
Alexeyev MF, Ledoux SP, Wilson GL. Mitochondrial DNA and aging. Clinical Science (London, England : 1979). 107: 355-64. PMID 15279618 DOI: 10.1042/Cs20040148 |
0.466 |
|
| 2004 |
Rachek LI, Grishko VI, Alexeyev MF, Pastukh VV, LeDoux SP, Wilson GL. Endonuclease III and endonuclease VIII conditionally targeted into mitochondria enhance mitochondrial DNA repair and cell survival following oxidative stress. Nucleic Acids Research. 32: 3240-7. PMID 15199172 DOI: 10.1093/Nar/Gkh648 |
0.606 |
|
| 2003 |
Druzhyna NM, Hollensworth SB, Kelley MR, Wilson GL, Ledoux SP. Targeting human 8-oxoguanine glycosylase to mitochondria of oligodendrocytes protects against menadione-induced oxidative stress. Glia. 42: 370-8. PMID 12730957 DOI: 10.1002/Glia.10230 |
0.64 |
|
| 2003 |
Shokolenko IN, Alexeyev MF, Robertson FM, LeDoux SP, Wilson GL. The expression of Exonuclease III from E. coli in mitochondria of breast cancer cells diminishes mitochondrial DNA repair capacity and cell survival after oxidative stress. Dna Repair. 2: 471-82. PMID 12713808 DOI: 10.1016/S1568-7864(03)00019-3 |
0.634 |
|
| 2002 |
Bozner P, Wilson GL, Druzhyna NM, Bryant-Thomas TK, LeDoux SP, Wilson GL, Pappolla MA. Deficiency of chaperonin 60 in Down's syndrome. Journal of Alzheimer's Disease : Jad. 4: 479-86. PMID 12515899 DOI: 10.3233/Jad-2002-4604 |
0.388 |
|
| 2002 |
Rachek LI, Grishko VI, Musiyenko SI, Kelley MR, LeDoux SP, Wilson GL. Conditional targeting of the DNA repair enzyme hOGG1 into mitochondria. The Journal of Biological Chemistry. 277: 44932-7. PMID 12244119 DOI: 10.1074/Jbc.M208770200 |
0.652 |
|
| 2002 |
Dobson AW, Grishko V, LeDoux SP, Kelley MR, Wilson GL, Gillespie MN. Enhanced mtDNA repair capacity protects pulmonary artery endothelial cells from oxidant-mediated death. American Journal of Physiology. Lung Cellular and Molecular Physiology. 283: L205-10. PMID 12060578 DOI: 10.1152/Ajplung.00443.2001 |
0.597 |
|
| 2002 |
Dobson AW, Kelley MR, Wilson GL, LeDoux SP. Targeting DNA repair proteins to mitochondria. Methods in Molecular Biology (Clifton, N.J.). 197: 351-62. PMID 12013809 DOI: 10.1385/1-59259-284-8:351 |
0.548 |
|
| 2001 |
Shokolenko I, Oberyszyn TM, D'Ambrosio SM, Saavedra JE, Keefer LK, LeDoux SP, Wilson GL, Robertson FM. Protection of human keratinocyte mtDNA by low-level nitric oxide. Nitric Oxide : Biology and Chemistry / Official Journal of the Nitric Oxide Society. 5: 555-60. PMID 11730362 DOI: 10.1006/Niox.2001.0381 |
0.59 |
|
| 2001 |
LeDoux SP, Wilson GL. Base excision repair of mitochondrial DNA damage in mammalian cells. Progress in Nucleic Acid Research and Molecular Biology. 68: 273-84. PMID 11554303 |
0.528 |
|
| 2001 |
Grishko V, Solomon M, Wilson GL, LeDoux SP, Gillespie MN. Oxygen radical-induced mitochondrial DNA damage and repair in pulmonary vascular endothelial cell phenotypes. American Journal of Physiology. Lung Cellular and Molecular Physiology. 280: L1300-8. PMID 11350811 DOI: 10.1152/Ajplung.2001.280.6.L1300 |
0.577 |
|
| 2001 |
Grishko V, Solomon M, Breit JF, Killilea DW, Ledoux SP, Wilson GL, Gillespie MN. Hypoxia promotes oxidative base modifications in the pulmonary artery endothelial cell VEGF gene. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 15: 1267-9. PMID 11344109 DOI: 10.1096/Fj.00-0755Fje |
0.363 |
|
| 2000 |
Druzhyna N, Smulson ME, LeDoux SP, Wilson GL. Poly(ADP-ribose) polymerase facilitates the repair of N-methylpurines in mitochondrial DNA. Diabetes. 49: 1849-55. PMID 11078451 DOI: 10.2337/Diabetes.49.11.1849 |
0.587 |
|
| 2000 |
Rodriguez H, Akman SA, Holmquist GP, Wilson GL, Driggers WJ, LeDoux SP. Mapping oxidative DNA damage using ligation-mediated polymerase chain reaction technology. Methods (San Diego, Calif.). 22: 148-56. PMID 11020329 DOI: 10.1006/Meth.2000.1055 |
0.54 |
|
| 2000 |
Dobson AW, Xu Y, Kelley MR, LeDoux SP, Wilson GL. Enhanced mitochondrial DNA repair and cellular survival after oxidative stress by targeting the human 8-oxoguanine glycosylase repair enzyme to mitochondria. The Journal of Biological Chemistry. 275: 37518-23. PMID 10982789 DOI: 10.1074/Jbc.M000831200 |
0.631 |
|
| 2000 |
Hollensworth SB, Shen C, Sim JE, Spitz DR, Wilson GL, LeDoux SP. Glial cell type-specific responses to menadione-induced oxidative stress. Free Radical Biology & Medicine. 28: 1161-74. PMID 10889445 DOI: 10.1016/S0891-5849(00)00214-8 |
0.523 |
|
| 1999 |
Pappolla MA, Chyan YJ, Poeggeler B, Bozner P, Ghiso J, LeDoux SP, Wilson GL. Alzheimer beta protein mediated oxidative damage of mitochondrial DNA: prevention by melatonin. Journal of Pineal Research. 27: 226-9. PMID 10551770 DOI: 10.1111/J.1600-079X.1999.Tb00619.X |
0.429 |
|
| 1999 |
Grishko VI, Druzhyna N, LeDoux SP, Wilson GL. Nitric oxide-induced damage to mtDNA and its subsequent repair. Nucleic Acids Research. 27: 4510-6. PMID 10536162 DOI: 10.1093/Nar/27.22.4510 |
0.641 |
|
| 1999 |
LeDoux SP, Driggers WJ, Hollensworth BS, Wilson GL. Repair of alkylation and oxidative damage in mitochondrial DNA. Mutation Research. 434: 149-59. PMID 10486589 DOI: 10.1016/S0921-8777(99)00026-9 |
0.638 |
|
| 1998 |
Druzhyna N, Nair RG, LeDoux SP, Wilson GL. Defective repair of oxidative damage in mitochondrial DNA in Down's syndrome. Mutation Research. 409: 81-9. PMID 9838924 DOI: 10.1016/S0921-8777(98)00042-1 |
0.579 |
|
| 1998 |
Ledoux SP, Shen CC, Grishko VI, Fields PA, Gard AL, Wilson GL. Glial cell-specific differences in response to alkylation damage. Glia. 24: 304-12. PMID 9775981 DOI: 10.1002/(Sici)1098-1136(199811)24:3<304::Aid-Glia4>3.0.Co;2-1 |
0.624 |
|
| 1997 |
Bozner P, Grishko V, LeDoux SP, Wilson GL, Chyan YC, Pappolla MA. The amyloid beta protein induces oxidative damage of mitochondrial DNA. Journal of Neuropathology and Experimental Neurology. 56: 1356-62. PMID 9413284 DOI: 10.1097/00005072-199712000-00010 |
0.541 |
|
| 1997 |
Driggers WJ, Holmquist GP, LeDoux SP, Wilson GL. Mapping frequencies of endogenous oxidative damage and the kinetic response to oxidative stress in a region of rat mtDNA. Nucleic Acids Research. 25: 4362-9. PMID 9336469 DOI: 10.1093/Nar/25.21.4362 |
0.606 |
|
| 1997 |
Grishko VI, Driggers WJ, LeDoux SP, Wilson GL. Repair of oxidative damage in nuclear DNA sequences with different transcriptional activities. Mutation Research. 384: 73-80. PMID 9298116 DOI: 10.1016/S0921-8777(97)00017-7 |
0.585 |
|
| 1997 |
Wilson GL, Patton NJ, LeDoux SP. Mitochondrial DNA in beta-cells is a sensitive target for damage by nitric oxide. Diabetes. 46: 1291-5. PMID 9231653 DOI: 10.2337/Diab.46.8.1291 |
0.543 |
|
| 1997 |
Bozner L, Wilson G, Ledoux S, Chvan J, Pappolla MA. OXIDATIVE DAMAGE OF MITOCHODRIAL DNA IN PC 12 CELLS FOLLOWING EXPOSURE TO AN AMYLOID (3-PROTEIN Journal of Neuropathology and Experimental Neurology. 56: 574. DOI: 10.1097/00005072-199705000-00027 |
0.539 |
|
| 1996 |
LeDoux SP, Williams BA, Hollensworth BS, Shen C, Thomale J, Rajewsky MF, Brent TP, Wilson GL. Glial cell-specific differences in repair of O6-methylguanine. Cancer Research. 56: 5615-9. PMID 8971165 |
0.618 |
|
| 1996 |
Ray LS, Chatterjee S, Berger NA, Grishko VI, LeDoux SP, Wilson GL. Catalytic activity of poly(ADP-ribose) polymerase is necessary for repair of N-methylpurines in nontranscribed, but not in transcribed, nuclear DNA sequences. Mutation Research. 363: 105-14. PMID 8676924 DOI: 10.1016/0921-8777(96)00005-5 |
0.559 |
|
| 1996 |
Driggers WJ, Grishko VI, LeDoux SP, Wilson GL. Defective repair of oxidative damage in the mitochondrial DNA of a xeroderma pigmentosum group A cell line. Cancer Research. 56: 1262-6. PMID 8640811 |
0.558 |
|
| 1995 |
Shen Cc, Wertelecki W, Driggers WJ, LeDoux SP, Wilson GL. Repair of mitochondrial DNA damage induced by bleomycin in human cells Mutation Research-Dna Repair. 337: 19-23. PMID 7541109 DOI: 10.1016/0921-8777(95)00008-8 |
0.644 |
|
| 1993 |
LeDoux SP, Patton NJ, Avery LJ, Wilson GL. Repair of N-methylpurines in the mitochondrial DNA of xeroderma pigmentosum complementation group D cells Carcinogenesis. 14: 913-917. PMID 8504484 DOI: 10.1093/carcin/14.5.913 |
0.494 |
|
| 1993 |
Driggers WJ, LeDoux SP, Wilson GL. Repair of oxidative damage within the mitochondrial DNA of RINr 38 cells Journal of Biological Chemistry. 268: 22042-22045. PMID 8408062 |
0.612 |
|
| 1993 |
Nelson JW, Ledoux SP, Wilson GL. Repair of O6-methylguanine in Rat pancreatic β-cells after exposure to N-methyl-N-nitrosourea Diabetes. 42: 1187-1194. PMID 8325451 DOI: 10.2337/Diab.42.8.1187 |
0.475 |
|
| 1992 |
LeDoux SP, Wilson GL, Beecham EJ, Stevnsner T, Wassermann K, Bohr VA. Repair of mitochondrial DNA after various types of DNA damage in Chinese hamster ovary cells Carcinogenesis. 13: 1967-1973. PMID 1423864 DOI: 10.1093/Carcin/13.11.1967 |
0.653 |
|
| 1991 |
LeDoux SP, Bohr VA, Thangada M, Wilson GL. Heterogeneous Repair of Methylnitrosourea-induced Alkali-labile Sites in Different DNA Sequences Cancer Research. 51: 775-779. PMID 1899045 |
0.333 |
|
| 1991 |
Pettepher CC, LeDoux SP, Bohr VA, Wilson GL. Repair of alkali-labile sites within the mitochondrial DNA of RINr 38 cells after exposure to the nitrosourea streptozotocin Journal of Biological Chemistry. 266: 3113-3117. PMID 1825207 |
0.554 |
|
| 1990 |
LeDoux SP, Patton NJ, Nelson JW, Bohr VA, Wilson GL. Preferential DNA repair of alkali-labile sites within the active insulin gene Journal of Biological Chemistry. 265: 14875-14880. PMID 2203764 |
0.314 |
|
| 1988 |
LeDoux SP, Hall CR, Forbes PM, Patton NJ, Wilson GL. Mechanisms of nicotinamide and thymidine protection from alloxan and streptozocin toxicity. Diabetes. 37: 1015-9. PMID 2968936 DOI: 10.2337/Diab.37.8.1015 |
0.485 |
|
| 1988 |
Wilson GL, Hartig PC, Patton NJ, LeDoux SP. Mechanisms of nitrosourea-induced β-cell damage. Activation of poly(ADP-ribose) synthetase and cellular distribution Diabetes. 37: 213-216. PMID 2968935 DOI: 10.2337/Diab.37.2.213 |
0.423 |
|
| 1986 |
LeDoux SP, Woodley SE, Patton NJ, Wilson GL. Mechanisms of nitrosourea-induced beta-cell damage. Alterations in DNA. Diabetes. 35: 866-72. PMID 2942432 DOI: 10.2337/Diab.35.8.866 |
0.545 |
|
| 1984 |
Ledoux SP, Wilson GL. Effects of streptozotocin on a clonal isolate of rat insulinoma cells Bba - Molecular Cell Research. 804: 387-392. PMID 6087920 DOI: 10.1016/0167-4889(84)90064-8 |
0.512 |
|
| Show low-probability matches. |