Sarah Moghadam, Pharm.D - Related publications

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50 most relevant papers in past 60 days:
Year Citation  Score
2020 Pérez-González M, Mendioroz M, Badesso S, Sucunza D, Roldan M, Espelosín M, Ursua S, Luján R, Cuadrado-Tejedor M, Garcia-Osta A. PLA2G4E, a candidate gene for resilience in Alzheimer´s disease and a new target for dementia treatment. Progress in Neurobiology. 101818. PMID 32380223 DOI: 10.1016/j.pneurobio.2020.101818   
2020 Zhao Y, Qian R, Zhang J, Liu F, Iqbal K, Dai CL, Gong CX. Young blood plasma reduces Alzheimer's disease-like brain pathologies and ameliorates cognitive impairment in 3×Tg-AD mice. Alzheimer's Research & Therapy. 12: 70. PMID 32513253 DOI: 10.1186/s13195-020-00639-w   
2020 Wei JP, Wen W, Dai Y, Qin LX, Wen YQ, Duan DD, Xu SJ. Drinking water temperature affects cognitive function and progression of Alzheimer's disease in a mouse model. Acta Pharmacologica Sinica. PMID 32451415 DOI: 10.1038/s41401-020-0407-5   
2020 Zaldua S, Damen FC, Pisharody R, Thomas R, Fan KD, Ekkurthi GK, Scheinman SB, Alahmadi S, Marottoli FM, Alford S, Cai K, Tai LM. Epidermal growth factor treatment of female mice that express at an age of advanced pathology mitigates behavioral and cerebrovascular dysfunction. Heliyon. 6: e03919. PMID 32478184 DOI: 10.1016/j.heliyon.2020.e03919   
2020 Ferreiro E, Lanzillo M, Canhoto D, Carvalho da Silva AM, Mota SI, Dias IS, Ferreira IL, Fontes AR, Mastrella G, Pinheiro P, Valero J, Rego AC. Chronic hyperglycemia impairs hippocampal neurogenesis and memory in an Alzheimer's disease mouse model. Neurobiology of Aging. 92: 98-113. PMID 32417750 DOI: 10.1016/j.neurobiolaging.2020.04.003   
2020 Liu J, Yu C, Li R, Liu K, Jin G, Ge R, Tang F, Cui S. High-altitude Tibetan fermented milk ameliorated cognitive dysfunction by modified gut microbiota in Alzheimer's disease transgenic mice. Food & Function. PMID 32458851 DOI: 10.1039/c9fo03007g   
2020 Zameer S, Alam M, Hussain S, Vohora D, Ali J, Akhtar M. Neuroprotective role of alendronate against APP processing and neuroinflammation in mice fed a high fat diet. Brain Research Bulletin. PMID 32389800 DOI: 10.1016/j.brainresbull.2020.04.010   
2020 Liu B, Kou J, Li F, Huo D, Xu J, Zhou X, Meng D, Ghulam M, Artyom B, Gao X, Ma N, Han D. Lemon essential oil ameliorates age-associated cognitive dysfunction via modulating hippocampal synaptic density and inhibiting acetylcholinesterase. Aging. 12. PMID 32392535 DOI: 10.18632/aging.103179   
2020 Lin SY, Wang TQ, Xu LT, Lai XX, Shen Y, Lin JW, Gao SY, Hu HY. Qingxin Kaiqiao Recipe Improves Cognitive Performance, Inhibits Apoptosis, and Reduces Pathological Deposits in APP/PS1 Double Transgenic Mice via the PI3K/Akt Pathway. Evidence-Based Complementary and Alternative Medicine : Ecam. 2020: 3019674. PMID 32419798 DOI: 10.1155/2020/3019674   
2020 Ghosh A, Mizuno K, Tiwari SS, Proitsi P, Gomez Perez-Nievas B, Glennon E, Martinez-Nunez RT, Giese KP. Alzheimer's disease-related dysregulation of mRNA translation causes key pathological features with ageing. Translational Psychiatry. 10: 192. PMID 32546772 DOI: 10.1038/s41398-020-00882-7   
2020 Mayagoitia K, Shin SD, Rubini M, Siebold L, Wilson CG, Bellinger DL, Figueroa JD, Soriano S. Short-term exposure to dietary cholesterol is associated with downregulation of interleukin-15, reduced thigmotaxis and memory impairment in mice. Behavioural Brain Research. 112779. PMID 32585301 DOI: 10.1016/j.bbr.2020.112779   
2020 Wu Q, Wang B, Li QF, Zhang X, Ntim M, Wu XF, Li N, Zhu DD, Jiang R, Yang JY, Yuan YH, Li S. SRC-1 Knockout Exerts No Effect on Amyloid β Deposition in APP/PS1 Mice. Frontiers in Aging Neuroscience. 12: 145. PMID 32625077 DOI: 10.3389/fnagi.2020.00145   
2020 Ferreira S, Pitman KA, Wang S, Summers BS, Bye N, Young KM, Cullen CL. Amyloidosis is associated with thicker myelin and increased oligodendrogenesis in the adult mouse brain. Journal of Neuroscience Research. PMID 32557778 DOI: 10.1002/jnr.24672   
2020 Zhang Y, Fung ITH, Sankar P, Chen X, Robison LS, Ye L, D'Souza SS, Salinero AE, Kuentzel ML, Chittur SV, Zhang W, Zuloaga KL, Yang Q. Depletion of NK Cells Improves Cognitive Function in the Alzheimer Disease Mouse Model. Journal of Immunology (Baltimore, Md. : 1950). PMID 32503894 DOI: 10.4049/jimmunol.2000037   
2020 Chen Y, Fang L, Chen S, Zhou H, Fan Y, Lin L, Li J, Xu J, Chen Y, Ma Y, Chen Y. Gut Microbiome Alterations Precede Cerebral Amyloidosis and Microglial Pathology in a Mouse Model of Alzheimer's Disease. Biomed Research International. 2020: 8456596. PMID 32596386 DOI: 10.1155/2020/8456596   
2020 Falangola MF, Nie X, Ward R, McKinnon ET, Dhiman S, Nietert PJ, Helpern JA, Jensen JH. Diffusion MRI detects early brain microstructure abnormalities in 2-month-old 3×Tg-AD mice. Nmr in Biomedicine. e4346. PMID 32557874 DOI: 10.1002/nbm.4346   
2020 Kim DH, Kim HA, Han YS, Jeon WK, Han JS. Recognition memory impairments and amyloid-beta deposition of the retrosplenial cortex at the early stage of 5XFAD mice. Physiology & Behavior. 112891. PMID 32442584 DOI: 10.1016/j.physbeh.2020.112891   
2020 Zhang L, Zhang Y, Hou Y, Li H, Li C, Xin J, Zhou N, Li Q, Song Y, Zhang Z. Total flavonoids of alleviates cognitive impairment in mice. Biomedical Reports. 13: 8. PMID 32607237 DOI: 10.3892/br.2020.1315   
2020 Izumi H, Kawahata I, Shinoda Y, Helmstetter FJ, Fukunaga K. SAK3 Administration Improves Spine Abnormalities and Cognitive Deficits in App Knock-in Mice by Increasing Proteasome Activity through CaMKII/Rpt6 Signaling. International Journal of Molecular Sciences. 21. PMID 32481611 DOI: 10.3390/ijms21113833   
2020 Sultan S, Taimuri U, Basnan SA, Ai-Orabi WK, Awadallah A, Almowald F, Hazazi A. Low Vitamin D and Its Association with Cognitive Impairment and Dementia. Journal of Aging Research. 2020: 6097820. PMID 32399297 DOI: 10.1155/2020/6097820   
2020 Wang S, Yao H, Xu Y, Hao R, Zhang W, Liu H, Huang Y, Guo W, Lu B. Therapeutic potential of a TrkB agonistic antibody for Alzheimer's disease. Theranostics. 10: 6854-6874. PMID 32550908 DOI: 10.7150/thno.44165   
2020 Kong Y, Peng Q, Lv N, Yuan J, Deng Z, Liang X, Chen S, Wang L. Paeoniflorin exerts neuroprotective effects in a transgenic mouse model of Alzheimer's disease via activation of adenosine A receptor. Neuroscience Letters. 135016. PMID 32371159 DOI: 10.1016/j.neulet.2020.135016   
2020 Wahle T, Sofranko A, Dekkers S, Miller MR, Heusinkveld HJ, Albrecht C, Cassee FR, Schins RPF. Evaluation of neurological effects of cerium dioxide nanoparticles doped with different amounts of zirconium following inhalation exposure in mouse models of Alzheimer's and vascular disease. Neurochemistry International. 104755. PMID 32422323 DOI: 10.1016/j.neuint.2020.104755   
2020 Li KY, Gong PF, Li JT, Xu NJ, Qin S. Morphological and molecular alterations of reactive astrocytes without proliferation in cerebral cortex of an APP/PS1 transgenic mouse model and Alzheimer's patients. Glia. PMID 32469469 DOI: 10.1002/glia.23845   
2020 Chen Y, Bian Y, Wang JW, Gong TT, Ying YM, Ma LF, Shan WG, Xie XQ, Zhan ZJ. Effects of α-Mangostin Derivatives on the Alzheimer's Disease Model of Rats and Their Mechanism: A Combination of Experimental Study and Computational Systems Pharmacology Analysis. Acs Omega. 5: 9846-9863. PMID 32391472 DOI: 10.1021/acsomega.0c00057   
2020 Sun Y, Sommerville NR, Liu JYH, Ngan MP, Poon D, Ponomarev ED, Lu Z, Kung JSC, Rudd JA. Intra-gastrointestinal amyloid-β1-42 oligomers perturb enteric function and induce Alzheimer's disease pathology. The Journal of Physiology. PMID 32617993 DOI: 10.1113/JP279919   
2020 Ortiz-Guerrero G, Gonzalez-Reyes RE, de-la-Torre A, Medina-Rincón G, Nava-Mesa MO. Pathophysiological Mechanisms of Cognitive Impairment and Neurodegeneration by Infection. Brain Sciences. 10. PMID 32545619 DOI: 10.3390/brainsci10060369   
2020 Wang S, Li K, Zhao S, Zhang X, Yang Z, Zhang J, Zhang T. Early-stage dysfunction of hippocampal theta and gamma oscillations and its modulation of neural network in a transgenic 5xFAD mouse model. Neurobiology of Aging. 94: 121-129. PMID 32619873 DOI: 10.1016/j.neurobiolaging.2020.05.002   
2020 Wang S, Li K, Zhao S, Zhang X, Yang Z, Zhang J, Zhang T. Early-stage dysfunction of hippocampal theta and gamma oscillations and its modulation of neural network in a transgenic 5xFAD mouse model. Neurobiology of Aging. 94: 121-129. PMID 32619873 DOI: 10.1016/j.neurobiolaging.2020.05.002   
2020 Wang S, Li K, Zhao S, Zhang X, Yang Z, Zhang J, Zhang T. Early-stage dysfunction of hippocampal theta and gamma oscillations and its modulation of neural network in a transgenic 5xFAD mouse model. Neurobiology of Aging. 94: 121-129. PMID 32619873 DOI: 10.1016/j.neurobiolaging.2020.05.002   
2020 Watt G, Chesworth R, Przybyla M, Ittner A, Garner B, Ittner LM, Karl T. Chronic cannabidiol (CBD) treatment did not exhibit beneficial effects in 4-month-old male TAU58/2 transgenic mice. Pharmacology, Biochemistry, and Behavior. 172970. PMID 32562718 DOI: 10.1016/j.pbb.2020.172970   
2020 Amidfar M, de Oliveira J, Kucharska E, Budni J, Kim YK. CREB and BDNF: Neurobiology and treatment of Alzheimer's disease. Life Sciences. 118020. PMID 32603820 DOI: 10.1016/j.lfs.2020.118020   
2020 Kim S, Nam Y, Kim C, Lee H, Hong S, Kim HS, Shin SJ, Park YH, Mai HN, Oh SM, Kim KS, Yoo DH, Chung WK, Chung H, Moon M. Neuroprotective and Anti-Inflammatory Effects of Low-Moderate Dose Ionizing Radiation in Models of Alzheimer's Disease. International Journal of Molecular Sciences. 21. PMID 32456197 DOI: 10.3390/ijms21103678   
2020 Beyer MMS, Lonnemann N, Remus A, Latz E, Heneka MT, Korte M. Enduring changes in neuronal function upon systemic inflammation are NLRP3 inflammasome dependent. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 32499379 DOI: 10.1523/JNEUROSCI.0200-20.2020   
2020 Huang J, van Zijl PCM, Han X, Dong CM, Cheng GWY, Tse KH, Knutsson L, Chen L, Lai JHC, Wu EX, Xu J, Chan KWY. Altered d-glucose in brain parenchyma and cerebrospinal fluid of early Alzheimer's disease detected by dynamic glucose-enhanced MRI. Science Advances. 6: eaba3884. PMID 32426510 DOI: 10.1126/sciadv.aba3884   
2020 Nakano M, Kubota K, Kobayashi E, Chikenji TS, Saito Y, Konari N, Fujimiya M. Bone marrow-derived mesenchymal stem cells improve cognitive impairment in an Alzheimer's disease model by increasing the expression of microRNA-146a in hippocampus. Scientific Reports. 10: 10772. PMID 32612165 DOI: 10.1038/s41598-020-67460-1   
2020 Schnöder L, Gasparoni G, Nordström K, Schottek A, Tomic I, Christmann A, Schäfer KH, Menger MD, Walter J, Fassbender K, Liu Y. Neuronal deficiency of p38α-MAPK ameliorates symptoms and pathology of APP or Tau-transgenic Alzheimer's mouse models. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 32475008 DOI: 10.1096/fj.201902731RR   
2020 Gao L, Li X, Meng S, Ma T, Wan L, Xu S. Chlorogenic Acid Alleviates Aβ-Induced Autophagy and Cognitive Impairment via the mTOR/TFEB Signaling Pathway. Drug Design, Development and Therapy. 14: 1705-1716. PMID 32440096 DOI: 10.2147/DDDT.S235969   
2020 Abe Y, Ikegawa N, Yoshida K, Muramatsu K, Hattori S, Kawai K, Murakami M, Tanaka T, Goda W, Goto M, Yamamoto T, Hashimoto T, Yamada K, Shibata T, Misawa H, et al. Behavioral and electrophysiological evidence for a neuroprotective role of aquaporin-4 in the 5xFAD transgenic mice model. Acta Neuropathologica Communications. 8: 67. PMID 32398151 DOI: 10.1186/s40478-020-00936-3   
2020 Uddin MS, Rahman MA, Kabir MT, Behl T, Mathew B, Perveen A, Barreto GE, Bin-Jumah MN, Abdel-Daim MM, Ashraf GM. Multifarious roles of mTOR signaling in cognitive aging and cerebrovascular dysfunction of Alzheimer's disease. Iubmb Life. PMID 32472959 DOI: 10.1002/iub.2324   
2020 Zhang H, Chen W, Tan Z, Zhang L, Dong Z, Cui W, Zhao K, Wang H, Jing H, Cao R, Kim C, Safar JG, Xiong WC, Mei L. A role of low-density lipoprotein receptor-related protein 4 (LRP4) in astrocytic Aβ clearance. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 32457076 DOI: 10.1523/JNEUROSCI.0250-20.2020   
2020 Xu Y, Hu R, He D, Zhou G, Wu H, Xu C, He B, Wu L, Wang Y, Chang Y, Ma R, Xie M, Xiao Z. Bisdemethoxycurcumin inhibits oxidative stress and antagonizes Alzheimer's disease by up-regulating SIRT1. Brain and Behavior. e01655. PMID 32441492 DOI: 10.1002/brb3.1655   
2020 He Z, Yang Y, Xing Z, Zuo Z, Wang R, Gu H, Qi F, Yao Z. Intraperitoneal injection of IFN-γ restores microglial autophagy, promotes amyloid-β clearance and improves cognition in APP/PS1 mice. Cell Death & Disease. 11: 440. PMID 32514180 DOI: 10.1038/s41419-020-2644-4   
2020 Tsuji M, Ohshima M, Yamamoto Y, Saito S, Hattori Y, Tanaka E, Taguchi A, Ihara M, Ogawa Y. Cilostazol, a Phosphodiesterase 3 Inhibitor, Moderately Attenuates Behaviors Depending on Sex in the Ts65Dn Mouse Model of Down Syndrome. Frontiers in Aging Neuroscience. 12: 106. PMID 32372946 DOI: 10.3389/fnagi.2020.00106   
2020 Liu Y, Xu S, Bian H, Qian Y, Li H, Shu S, Chen J, Cao X, Gu Y, Jin J, Zhang X, Xu Y, Zhu X. Xingnaojing ameliorates synaptic plasticity and memory deficits in an Aβ induced mouse model of Alzheimer's disease. Journal of Pharmacological Sciences. PMID 32482409 DOI: 10.1016/j.jphs.2020.05.002   
2020 Bracko O, Vinarcsik LK, Cruz Hernández JC, Ruiz-Uribe NE, Haft-Javaherian M, Falkenhain K, Ramanauskaite EM, Ali M, Mohapatra A, Swallow MA, Njiru BN, Muse V, Michelucci PE, Nishimura N, Schaffer CB. High fat diet worsens Alzheimer's disease-related behavioral abnormalities and neuropathology in APP/PS1 mice, but not by synergistically decreasing cerebral blood flow. Scientific Reports. 10: 9884. PMID 32555372 DOI: 10.1038/s41598-020-65908-y   
2020 Do J, Kim N, Jeon SH, Gee MS, Ju YJ, Kim JH, Oh MS, Lee JK. Trans-Cinnamaldehyde Alleviates Amyloid-Beta Pathogenesis via the SIRT1-PGC1α-PPARγ Pathway in 5XFAD Transgenic Mice. International Journal of Molecular Sciences. 21. PMID 32599846 DOI: 10.3390/ijms21124492   
2020 Li W, Wu M, Zhang Y, Wei X, Zang J, Liu Y, Wang Y, Gong CX, Wei W. Intermittent fasting promotes adult hippocampal neuronal differentiation by activating GSK-3β in 3xTg-AD mice. Journal of Neurochemistry. PMID 32578216 DOI: 10.1111/jnc.15105   
2020 Park D, Choi EK, Cho TH, Joo SS, Kim YB. Human Neural Stem Cells Encoding ChAT Gene Restore Cognitive Function via Acetylcholine Synthesis, Aβ Elimination, and Neuroregeneration in APPswe/PS1dE9 Mice. International Journal of Molecular Sciences. 21. PMID 32486466 DOI: 10.3390/ijms21113958   
2020 Cui W, Sun C, Ma Y, Wang S, Wang X, Zhang Y. Neuroprotective effect of tormentic acid against memory impairment and neuro‑inflammation in an Alzheimer's disease mouse model. Molecular Medicine Reports. PMID 32468017 DOI: 10.3892/mmr.2020.11154